| organelle organization | GO:0006996 | 227 | 0.248 | |
| multicellular organism growth | GO:0035264 | 4 | 0.161 | |
| aging | GO:0007568 | 2 | 0.113 | |
| protein localization to nucleus | GO:0034504 | 3 | 0.112 | |
| positive regulation of transport | GO:0051050 | 2 | 0.102 | |
| regulation of protein transport | GO:0051223 | 3 | 0.101 | |
| regulation of establishment of protein localization | GO:0070201 | 4 | 0.099 | |
| single organism organelle organization | GO:1902589 | 199 | 0.098 | |
| g2 dna damage checkpoint | GO:0031572 | 3 | 0.095 | |
| regulation of macromolecule metabolic process | GO:0060255 | 317 | 0.095 | |
| meiotic nuclear division | GO:0007126 | 4 | 0.093 | |
| mitotic g2 dna damage checkpoint | GO:0007095 | 3 | 0.090 | |
| regulation of metabolic process | GO:0019222 | 359 | 0.089 | |
| transport | GO:0006810 | 220 | 0.089 | |
| protein metabolic process | GO:0019538 | 183 | 0.088 | |
| nuclear transport | GO:0051169 | 4 | 0.087 | |
| regulation of intracellular protein transport | GO:0033157 | 3 | 0.086 | |
| single fertilization | GO:0007338 | 3 | 0.086 | |
| positive regulation of cell cycle | GO:0045787 | 3 | 0.085 | |
| regulation of protein import into nucleus | GO:0042306 | 2 | 0.080 | |
| regulation of protein localization to nucleus | GO:1900180 | 2 | 0.080 | |
| cognition | GO:0050890 | 1 | 0.079 | |
| mitotic g2 m transition checkpoint | GO:0044818 | 3 | 0.077 | |
| signal transduction | GO:0007165 | 455 | 0.076 | |
| cellular macromolecule metabolic process | GO:0044260 | 391 | 0.072 | |
| establishment of protein localization to organelle | GO:0072594 | 4 | 0.071 | |
| regulation of protein targeting | GO:1903533 | 2 | 0.069 | |
| meiotic cell cycle process | GO:1903046 | 3 | 0.069 | |
| spindle assembly | GO:0051225 | 2 | 0.066 | |
| protein import | GO:0017038 | 3 | 0.063 | |
| establishment of localization | GO:0051234 | 244 | 0.061 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 271 | 0.060 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 2 | 0.060 | |
| regulation of signaling | GO:0023051 | 235 | 0.059 | |
| cell migration | GO:0016477 | 237 | 0.057 | |
| nucleocytoplasmic transport | GO:0006913 | 4 | 0.056 | |
| nuclear import | GO:0051170 | 3 | 0.054 | |
| stem cell division | GO:0017145 | 1 | 0.051 | |
| protein import into nucleus | GO:0006606 | 3 | 0.051 | |
| cell motility | GO:0048870 | 244 | 0.050 | |
| response to abiotic stimulus | GO:0009628 | 122 | 0.050 | |
| system process | GO:0003008 | 185 | 0.049 | |
| gtp catabolic process | GO:0006184 | 2 | 0.049 | |
| mitotic dna integrity checkpoint | GO:0044774 | 4 | 0.048 | |
| single organism localization | GO:1902578 | 225 | 0.048 | |
| microtubule based process | GO:0007017 | 60 | 0.047 | |
| autophagy | GO:0006914 | 4 | 0.046 | |
| response to chemical | GO:0042221 | 320 | 0.043 | |
| single organism transport | GO:0044765 | 206 | 0.042 | |
| cell cycle | GO:0007049 | 93 | 0.042 | |
| regulation of cytoplasmic transport | GO:1903649 | 4 | 0.041 | |
| regulation of response to stimulus | GO:0048583 | 269 | 0.039 | |
| fertilization | GO:0009566 | 3 | 0.039 | |
| organic cyclic compound metabolic process | GO:1901360 | 301 | 0.039 | |
| cell projection organization | GO:0030030 | 284 | 0.039 | |
| single organism metabolic process | GO:0044710 | 217 | 0.037 | |
| small molecule metabolic process | GO:0044281 | 77 | 0.037 | |
| negative regulation of cellular process | GO:0048523 | 283 | 0.037 | |
| cellular protein modification process | GO:0006464 | 100 | 0.036 | |
| modification dependent protein catabolic process | GO:0019941 | 3 | 0.036 | |
| regulation of nucleoside metabolic process | GO:0009118 | 2 | 0.036 | |
| regulation of multicellular organismal process | GO:0051239 | 277 | 0.036 | |
| organic acid metabolic process | GO:0006082 | 31 | 0.036 | |
| regulation of localization | GO:0032879 | 104 | 0.036 | |
| locomotion | GO:0040011 | 313 | 0.034 | |
| cellular localization | GO:0051641 | 97 | 0.034 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 7 | 0.034 | |
| negative regulation of protein transport | GO:0051224 | 3 | 0.033 | |
| positive regulation of biological process | GO:0048518 | 253 | 0.033 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 4 | 0.032 | |
| macromolecular complex subunit organization | GO:0043933 | 74 | 0.032 | |
| cellular aromatic compound metabolic process | GO:0006725 | 295 | 0.032 | |
| endosomal transport | GO:0016197 | 2 | 0.032 | |
| positive regulation of catabolic process | GO:0009896 | 4 | 0.032 | |
| guanosine containing compound catabolic process | GO:1901069 | 2 | 0.031 | |
| positive regulation of secretion | GO:0051047 | 1 | 0.030 | |
| proteasomal protein catabolic process | GO:0010498 | 2 | 0.030 | |
| response to uv | GO:0009411 | 3 | 0.030 | |
| positive regulation of cellular catabolic process | GO:0031331 | 3 | 0.030 | |
| cellular amine metabolic process | GO:0044106 | 2 | 0.029 | |
| adult behavior | GO:0030534 | 2 | 0.029 | |
| negative regulation of biological process | GO:0048519 | 304 | 0.029 | |
| erk1 and erk2 cascade | GO:0070371 | 4 | 0.029 | |
| regulation of cellular biosynthetic process | GO:0031326 | 245 | 0.029 | |
| gtp metabolic process | GO:0046039 | 4 | 0.029 | |
| tube morphogenesis | GO:0035239 | 349 | 0.029 | |
| protein localization | GO:0008104 | 40 | 0.029 | |
| regionalization | GO:0003002 | 274 | 0.028 | |
| oxoacid metabolic process | GO:0043436 | 31 | 0.028 | |
| regulation of cell cycle | GO:0051726 | 52 | 0.028 | |
| maintenance of location | GO:0051235 | 4 | 0.028 | |
| negative regulation of protein kinase activity | GO:0006469 | 4 | 0.028 | |
| cytokinesis | GO:0000910 | 3 | 0.027 | |
| cytoskeleton organization | GO:0007010 | 96 | 0.027 | |
| nitrogen compound metabolic process | GO:0006807 | 319 | 0.027 | |
| regulation of primary metabolic process | GO:0080090 | 311 | 0.027 | |
| regulation of developmental process | GO:0050793 | 247 | 0.027 | |
| chordate embryonic development | GO:0043009 | 271 | 0.026 | |
| regulation of cellular amine metabolic process | GO:0033238 | 0 | 0.026 | |
| phagocytosis | GO:0006909 | 3 | 0.026 | |
| regulation of protein catabolic process | GO:0042176 | 1 | 0.025 | |
| growth | GO:0040007 | 174 | 0.025 | |
| positive regulation of secretion by cell | GO:1903532 | 1 | 0.025 | |
| stem cell proliferation | GO:0072089 | 4 | 0.025 | |
| mitotic dna damage checkpoint | GO:0044773 | 4 | 0.024 | |
| response to drug | GO:0042493 | 3 | 0.024 | |
| regulation of gene expression | GO:0010468 | 265 | 0.024 | |
| amine metabolic process | GO:0009308 | 2 | 0.024 | |
| regulation of gtp catabolic process | GO:0033124 | 2 | 0.024 | |
| larval development | GO:0002164 | 2 | 0.024 | |
| golgi vesicle transport | GO:0048193 | 3 | 0.023 | |
| carboxylic acid metabolic process | GO:0019752 | 22 | 0.023 | |
| negative regulation of kinase activity | GO:0033673 | 4 | 0.023 | |
| gene expression | GO:0010467 | 252 | 0.023 | |
| regulation of meiotic cell cycle | GO:0051445 | 1 | 0.023 | |
| intracellular signal transduction | GO:0035556 | 85 | 0.023 | |
| regulation of nucleotide catabolic process | GO:0030811 | 2 | 0.023 | |
| neuroblast proliferation | GO:0007405 | 2 | 0.023 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 2 | 0.022 | |
| cellular component disassembly | GO:0022411 | 1 | 0.022 | |
| protein phosphorylation | GO:0006468 | 47 | 0.022 | |
| macromolecule localization | GO:0033036 | 54 | 0.022 | |
| cellular nitrogen compound metabolic process | GO:0034641 | 290 | 0.022 | |
| central nervous system development | GO:0007417 | 387 | 0.022 | |
| localization of cell | GO:0051674 | 244 | 0.022 | |
| negative regulation of metabolic process | GO:0009892 | 86 | 0.022 | |
| organonitrogen compound metabolic process | GO:1901564 | 74 | 0.022 | |
| regulation of multicellular organism growth | GO:0040014 | 4 | 0.021 | |
| regulation of metal ion transport | GO:0010959 | 4 | 0.021 | |
| spermatid development | GO:0007286 | 2 | 0.021 | |
| protein complex subunit organization | GO:0071822 | 46 | 0.021 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 3 | 0.021 | |
| nucleic acid metabolic process | GO:0090304 | 244 | 0.020 | |
| chemosensory behavior | GO:0007635 | 1 | 0.020 | |
| establishment of localization in cell | GO:0051649 | 77 | 0.020 | |
| single organism nuclear import | GO:1902593 | 3 | 0.020 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 2 | 0.020 | |
| morphogenesis of an epithelium | GO:0002009 | 333 | 0.020 | |
| wnt signaling pathway | GO:0016055 | 80 | 0.020 | |
| regulation of response to extracellular stimulus | GO:0032104 | 1 | 0.020 | |
| neuron neuron synaptic transmission | GO:0007270 | 1 | 0.019 | |
| negative regulation of intracellular protein transport | GO:0090317 | 3 | 0.019 | |
| translational initiation | GO:0006413 | 3 | 0.019 | |
| negative regulation of mapk cascade | GO:0043409 | 4 | 0.019 | |
| exocytosis | GO:0006887 | 1 | 0.019 | |
| peptidyl serine phosphorylation | GO:0018105 | 1 | 0.019 | |
| regulation of biological quality | GO:0065008 | 263 | 0.019 | |
| regulation of synapse assembly | GO:0051963 | 3 | 0.019 | |
| regulation of reproductive process | GO:2000241 | 4 | 0.019 | |
| cellular catabolic process | GO:0044248 | 27 | 0.019 | |
| mitotic cell cycle | GO:0000278 | 64 | 0.019 | |
| regulation of cell communication | GO:0010646 | 232 | 0.019 | |
| positive regulation of exocytosis | GO:0045921 | 1 | 0.019 | |
| negative regulation of protein phosphorylation | GO:0001933 | 4 | 0.019 | |
| lipid storage | GO:0019915 | 1 | 0.018 | |
| regulation of signal transduction | GO:0009966 | 225 | 0.018 | |
| protein targeting to nucleus | GO:0044744 | 3 | 0.018 | |
| protein complex assembly | GO:0006461 | 30 | 0.018 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 76 | 0.018 | |
| negative regulation of nucleocytoplasmic transport | GO:0046823 | 2 | 0.018 | |
| membrane invagination | GO:0010324 | 1 | 0.018 | |
| cell morphogenesis | GO:0000902 | 289 | 0.018 | |
| nucleobase containing compound metabolic process | GO:0006139 | 274 | 0.018 | |
| regulation of protein complex assembly | GO:0043254 | 3 | 0.017 | |
| rna localization | GO:0006403 | 4 | 0.017 | |
| regulation of cellular component organization | GO:0051128 | 86 | 0.017 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 0 | 0.017 | |
| cellular amino acid metabolic process | GO:0006520 | 7 | 0.017 | |
| digestive system development | GO:0055123 | 289 | 0.017 | |
| synaptic growth at neuromuscular junction | GO:0051124 | 2 | 0.017 | |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 1 | 0.017 | |
| phagocytosis engulfment | GO:0006911 | 1 | 0.017 | |
| spermatid differentiation | GO:0048515 | 2 | 0.017 | |
| cellular protein metabolic process | GO:0044267 | 129 | 0.017 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 3 | 0.017 | |
| protein dephosphorylation | GO:0006470 | 3 | 0.017 | |
| positive regulation of cellular process | GO:0048522 | 201 | 0.017 | |
| cellular component biogenesis | GO:0044085 | 178 | 0.017 | |
| regulation of dendrite development | GO:0050773 | 3 | 0.017 | |
| protein modification process | GO:0036211 | 100 | 0.017 | |
| guanosine containing compound metabolic process | GO:1901068 | 4 | 0.017 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 3 | 0.016 | |
| response to stress | GO:0006950 | 263 | 0.016 | |
| regulation of multicellular organismal development | GO:2000026 | 223 | 0.016 | |
| response to hydrogen peroxide | GO:0042542 | 3 | 0.016 | |
| immune system process | GO:0002376 | 241 | 0.016 | |
| negative regulation of cytoplasmic transport | GO:1903650 | 2 | 0.016 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 1 | 0.016 | |
| positive regulation of jnk cascade | GO:0046330 | 3 | 0.016 | |
| rho protein signal transduction | GO:0007266 | 5 | 0.016 | |
| cellular response to stress | GO:0033554 | 62 | 0.016 | |
| microtubule organizing center organization | GO:0031023 | 1 | 0.016 | |
| negative regulation of intracellular transport | GO:0032387 | 3 | 0.016 | |
| neurological system process | GO:0050877 | 62 | 0.016 | |
| multi organism process | GO:0051704 | 134 | 0.016 | |
| cellular ketone metabolic process | GO:0042180 | 11 | 0.016 | |
| negative regulation of map kinase activity | GO:0043407 | 2 | 0.016 | |
| muscle structure development | GO:0061061 | 196 | 0.016 | |
| positive regulation of cell activation | GO:0050867 | 1 | 0.015 | |
| small gtpase mediated signal transduction | GO:0007264 | 8 | 0.015 | |
| response to light stimulus | GO:0009416 | 46 | 0.015 | |
| regulation of cell activation | GO:0050865 | 1 | 0.015 | |
| positive regulation of cell adhesion | GO:0045785 | 1 | 0.015 | |
| cellular response to nutrient levels | GO:0031669 | 2 | 0.015 | |
| heterocycle metabolic process | GO:0046483 | 290 | 0.015 | |
| response to organic substance | GO:0010033 | 153 | 0.015 | |
| peptide transport | GO:0015833 | 1 | 0.015 | |
| positive regulation of map kinase activity | GO:0043406 | 3 | 0.015 | |
| synaptic vesicle localization | GO:0097479 | 1 | 0.014 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 3 | 0.014 | |
| hormone secretion | GO:0046879 | 2 | 0.014 | |
| regulation of organelle organization | GO:0033043 | 29 | 0.014 | |
| actin filament based process | GO:0030029 | 64 | 0.014 | |
| positive regulation of stress activated protein kinase signaling cascade | GO:0070304 | 3 | 0.014 | |
| organelle assembly | GO:0070925 | 110 | 0.014 | |
| forebrain cell migration | GO:0021885 | 1 | 0.014 | |
| regulation of synapse organization | GO:0050807 | 3 | 0.014 | |
| macromolecule biosynthetic process | GO:0009059 | 227 | 0.014 | |
| regulation of translational initiation | GO:0006446 | 1 | 0.014 | |
| cellular response to chemical stimulus | GO:0070887 | 157 | 0.014 | |
| mitotic cell cycle checkpoint | GO:0007093 | 5 | 0.014 | |
| carbohydrate homeostasis | GO:0033500 | 1 | 0.014 | |
| macromolecule modification | GO:0043412 | 111 | 0.014 | |
| cell cycle process | GO:0022402 | 53 | 0.014 | |
| regulation of exocytosis | GO:0017157 | 1 | 0.014 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 191 | 0.014 | |
| negative regulation of protein complex assembly | GO:0031333 | 1 | 0.014 | |
| intracellular mrna localization | GO:0008298 | 1 | 0.014 | |
| response to external stimulus | GO:0009605 | 264 | 0.014 | |
| regulation of synaptic plasticity | GO:0048167 | 1 | 0.013 | |
| meiosis i | GO:0007127 | 1 | 0.013 | |
| regulation of gtpase activity | GO:0043087 | 2 | 0.013 | |
| positive regulation of i kappab kinase nf kappab signaling | GO:0043123 | 3 | 0.013 | |
| negative regulation of protein localization to nucleus | GO:1900181 | 2 | 0.013 | |
| establishment or maintenance of cell polarity | GO:0007163 | 29 | 0.013 | |
| meiotic spindle organization | GO:0000212 | 1 | 0.013 | |
| cellular component movement | GO:0006928 | 335 | 0.013 | |
| microtubule cytoskeleton organization | GO:0000226 | 33 | 0.013 | |
| ras protein signal transduction | GO:0007265 | 7 | 0.013 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 0 | 0.013 | |
| regulation of rho protein signal transduction | GO:0035023 | 2 | 0.013 | |
| regulation of cell differentiation | GO:0045595 | 142 | 0.013 | |
| cell part morphogenesis | GO:0032990 | 246 | 0.013 | |
| positive regulation of cell division | GO:0051781 | 2 | 0.013 | |
| cytoplasm organization | GO:0007028 | 4 | 0.013 | |
| neuron differentiation | GO:0030182 | 353 | 0.013 | |
| cellular response to organic substance | GO:0071310 | 105 | 0.013 | |
| pole plasm assembly | GO:0007315 | 4 | 0.013 | |
| neuron projection morphogenesis | GO:0048812 | 161 | 0.013 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 14 | 0.013 | |
| regulation of autophagy | GO:0010506 | 3 | 0.012 | |
| somatic muscle development | GO:0007525 | 4 | 0.012 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 1 | 0.012 | |
| negative regulation of protein import into nucleus | GO:0042308 | 2 | 0.012 | |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 2 | 0.012 | |
| cell surface receptor signaling pathway | GO:0007166 | 325 | 0.012 | |
| regulation of protein polymerization | GO:0032271 | 2 | 0.012 | |
| response to radiation | GO:0009314 | 51 | 0.012 | |
| regulation of mitotic cell cycle | GO:0007346 | 25 | 0.012 | |
| phosphorylation | GO:0016310 | 69 | 0.012 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 107 | 0.012 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 1 | 0.012 | |
| regulation of transport | GO:0051049 | 45 | 0.012 | |
| phosphate containing compound metabolic process | GO:0006796 | 108 | 0.012 | |
| locomotor rhythm | GO:0045475 | 3 | 0.012 | |
| cellular response to extracellular stimulus | GO:0031668 | 2 | 0.012 | |
| positive regulation of response to stimulus | GO:0048584 | 80 | 0.012 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 1 | 0.012 | |
| cell projection morphogenesis | GO:0048858 | 244 | 0.012 | |
| hemopoiesis | GO:0030097 | 183 | 0.011 | |
| urogenital system development | GO:0001655 | 97 | 0.011 | |
| embryonic organ morphogenesis | GO:0048562 | 274 | 0.011 | |
| digestive tract development | GO:0048565 | 265 | 0.011 | |
| blood vessel development | GO:0001568 | 246 | 0.011 | |
| mitotic cell cycle phase transition | GO:0044772 | 9 | 0.011 | |
| lateral inhibition | GO:0046331 | 1 | 0.011 | |
| cellular carbohydrate metabolic process | GO:0044262 | 4 | 0.011 | |
| sensory organ development | GO:0007423 | 393 | 0.011 | |
| regulation of cell cycle process | GO:0010564 | 20 | 0.011 | |
| regulation of programmed cell death | GO:0043067 | 101 | 0.011 | |
| regulation of cellular metabolic process | GO:0031323 | 320 | 0.011 | |
| developmental growth | GO:0048589 | 166 | 0.011 | |
| establishment of cell polarity | GO:0030010 | 18 | 0.011 | |
| negative regulation of jnk cascade | GO:0046329 | 1 | 0.011 | |
| brain development | GO:0007420 | 293 | 0.011 | |
| cilium morphogenesis | GO:0060271 | 85 | 0.011 | |
| regulation of chromosome segregation | GO:0051983 | 1 | 0.011 | |
| osteoclast differentiation | GO:0030316 | 1 | 0.011 | |
| interspecies interaction between organisms | GO:0044419 | 4 | 0.011 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 8 | 0.010 | |
| positive regulation of stem cell proliferation | GO:2000648 | 1 | 0.010 | |
| regulation of glial cell differentiation | GO:0045685 | 4 | 0.010 | |
| negative regulation of response to stimulus | GO:0048585 | 104 | 0.010 | |
| phosphorus metabolic process | GO:0006793 | 109 | 0.010 | |
| regulation of calcium ion transport | GO:0051924 | 2 | 0.010 | |
| negative regulation of small gtpase mediated signal transduction | GO:0051058 | 1 | 0.010 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 1 | 0.010 | |
| protein complex disassembly | GO:0043241 | 1 | 0.010 | |
| axis specification | GO:0009798 | 43 | 0.010 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 4 | 0.010 | |
| centrosome cycle | GO:0007098 | 1 | 0.010 | |
| negative regulation of ras protein signal transduction | GO:0046580 | 1 | 0.010 | |
| er to golgi vesicle mediated transport | GO:0006888 | 1 | 0.010 | |
