Danio rerio

30 known processes

nr4a2a

nuclear receptor subfamily 4, group A, member 2a

nr4a2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
central nervous system developmentGO:00074173870.366
brain developmentGO:00074202930.250
cellular biosynthetic processGO:00442492860.242
Human Mouse Worm
adult behaviorGO:003053420.207
Mouse
head developmentGO:00603223030.204
cellular aromatic compound metabolic processGO:00067252950.171
Human Mouse Worm
nitrogen compound metabolic processGO:00068073190.158
Human Mouse Worm
dopaminergic neuron differentiationGO:0071542140.142
organic substance biosynthetic processGO:19015762890.139
Human Mouse Worm
regulation of multicellular organismal processGO:00512392770.131
Mouse Worm Fly
response to amineGO:001407510.129
Mouse
cellular nitrogen compound metabolic processGO:00346412900.127
Human Mouse Worm
generation of neuronsGO:00486993850.111
cellular nitrogen compound biosynthetic processGO:00442712180.111
Human Mouse Worm
camera type eye developmentGO:00430102220.106
organic cyclic compound metabolic processGO:19013603010.106
Human Mouse Worm
negative regulation of biological processGO:00485193040.101
Mouse
organic cyclic compound biosynthetic processGO:19013622230.098
Human Mouse Worm
gabaergic neuron differentiationGO:009715420.096
nucleic acid templated transcriptionGO:00976591810.096
Human Mouse Worm
regulation of nucleobase containing compound metabolic processGO:00192192500.095
Mouse Worm
gene expressionGO:00104672520.094
Human Mouse Worm
regulation of anatomical structure morphogenesisGO:00226031300.088
sensory perception of chemical stimulusGO:000760630.086
signal transductionGO:00071654550.085
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.085
multicellular organism growthGO:003526440.085
regulation of nitrogen compound metabolic processGO:00511712510.084
Mouse Worm
positive regulation of nucleic acid templated transcriptionGO:1903508570.083
Mouse Worm
diencephalon developmentGO:0021536580.082
Mouse
positive regulation of biological processGO:00485182530.082
Mouse Worm
positive regulation of cellular biosynthetic processGO:0031328680.080
Mouse Worm
amine metabolic processGO:000930820.078
Mouse
regulation of cellular amine metabolic processGO:003323800.076
Mouse
cellular component movementGO:00069283350.076
Mouse
central nervous system neuron axonogenesisGO:0021955180.075
Mouse
cell migrationGO:00164772370.074
Mouse
neuron projection morphogenesisGO:00488121610.071
Mouse
macromolecule biosynthetic processGO:00090592270.071
Human Mouse Worm
cellular amine metabolic processGO:004410620.070
Mouse
central nervous system neuron differentiationGO:0021953740.069
regulation of cellular amino acid metabolic processGO:000652100.067
locomotionGO:00400113130.066
Mouse
regulation of metabolic processGO:00192223590.063
Mouse Worm
regulation of blood pressureGO:000821710.061
neuron differentiationGO:00301823530.060
stem cell maintenanceGO:001982740.060
nucleobase containing compound metabolic processGO:00061392740.059
Human Mouse Worm
response to abiotic stimulusGO:00096281220.059
Mouse
limbic system developmentGO:0021761160.058
response to organic substanceGO:00100331530.057
Mouse
negative regulation of cellular processGO:00485232830.056
Mouse
neurological system processGO:0050877620.055
cellular amino acid metabolic processGO:000652070.055
cellular macromolecule metabolic processGO:00442603910.055
Human Mouse Worm
behaviorGO:0007610740.055
Mouse
regulation of cellular macromolecule biosynthetic processGO:20001122220.055
Mouse Worm
sensory organ developmentGO:00074233930.054
regulation of cell deathGO:00109411030.054
Mouse
heterocycle biosynthetic processGO:00181302150.052
Human Mouse Worm
regulation of cellular biosynthetic processGO:00313262450.052
Mouse Worm
eye developmentGO:00016542770.051
cognitionGO:005089010.051
single organism transportGO:00447652060.050
Fly
regulation of macromolecule metabolic processGO:00602553170.049
Mouse Worm
response to hexoseGO:000974630.049
transcription dna templatedGO:00063511810.049
Human Mouse Worm
regulation of biosynthetic processGO:00098892500.048
Mouse Worm
response to chemicalGO:00422213200.048
Mouse Rat
organonitrogen compound metabolic processGO:1901564740.047
Mouse
rna biosynthetic processGO:00327741810.045
Human Mouse Worm
positive regulation of nitrogen compound metabolic processGO:0051173690.045
Mouse Worm
regulation of rna biosynthetic processGO:20011412130.045
Mouse Worm
regulation of programmed cell deathGO:00430671010.045
Mouse
phagocytosisGO:000690930.045
Fly
sensory organ morphogenesisGO:00905962000.044
forebrain developmentGO:0030900960.044
regulation of signalingGO:00230512350.044
negative regulation of gliogenesisGO:001401410.044
regulation of primary metabolic processGO:00800903110.043
Mouse Worm
regulation of cell differentiationGO:00455951420.043
transcription from rna polymerase ii promoterGO:0006366800.043
Mouse Worm
positive regulation of transcription dna templatedGO:0045893570.042
Mouse Worm
aromatic compound biosynthetic processGO:00194382170.042
Human Mouse Worm
positive regulation of cellular amino acid metabolic processGO:004576400.042
single organism metabolic processGO:00447102170.042
stem cell proliferationGO:007208940.041
neuron projection extensionGO:1990138450.041
nucleic acid metabolic processGO:00903042440.041
Human Mouse Worm
stem cell differentiationGO:00488631170.041
cellular ketone metabolic processGO:0042180110.041
regulation of gene expressionGO:00104682650.041
Mouse Worm
muscle structure developmentGO:00610611960.041
cell differentiation in spinal cordGO:0021515400.040
embryonic organ developmentGO:00485683810.040
carboxylic acid metabolic processGO:0019752220.040
monoamine transportGO:001584410.040
response to external stimulusGO:00096052640.040
Human Mouse
positive regulation of cellular amine metabolic processGO:003324000.040
organonitrogen compound biosynthetic processGO:1901566470.039
Mouse
regulation of developmental processGO:00507932470.039
Fly
biosynthetic processGO:00090582940.039
Human Mouse Worm
regulation of cellular metabolic processGO:00313233200.038
Mouse Worm
cell part morphogenesisGO:00329902460.038
Mouse
system processGO:00030081850.038
positive regulation of cellular metabolic processGO:0031325940.037
Mouse Worm
regulation of cell communicationGO:00106462320.037
rna metabolic processGO:00160702190.037
Human Mouse Worm
larval developmentGO:000216420.036
Worm
cell surface receptor signaling pathwayGO:00071663250.036
glutamate receptor signaling pathwayGO:000721510.035
cellular protein catabolic processGO:004425740.035
regulation of macromolecule biosynthetic processGO:00105562250.035
Mouse Worm
maintenance of locationGO:005123540.035
regulation of cellular ketone metabolic processGO:001056570.035
cell motilityGO:00488702440.034
Mouse
heterocycle metabolic processGO:00464832900.033
Human Mouse Worm
regulation of transcription from rna polymerase ii promoterGO:00063571140.033
Mouse Worm
ear developmentGO:00435831270.033
cell morphogenesis involved in differentiationGO:00009041950.033
Mouse
regulation of molecular functionGO:0065009700.033
Mouse
homeostatic processGO:00425921420.033
muscle tissue developmentGO:00605371100.032
response to stressGO:00069502630.032
Mouse
digestive system developmentGO:00551232890.031
midbrain hindbrain boundary developmentGO:0030917230.031
guanosine containing compound metabolic processGO:190106840.031
inner ear developmentGO:00488391260.030
localization of cellGO:00516742440.030
Mouse
developmental growth involved in morphogenesisGO:0060560860.030
agingGO:000756820.030
response to amphetamineGO:000197510.030
Mouse
neuron developmentGO:00486662620.030
catecholamine metabolic processGO:000658420.030
Mouse
programmed cell deathGO:00125011190.030
Mouse
regulation of biological qualityGO:00650082630.029
lateral inhibitionGO:004633110.029
phagocytosis engulfmentGO:000691110.029
chordate embryonic developmentGO:00430092710.029
regulation of rna metabolic processGO:00512522240.029
Mouse Worm
positive regulation of rna biosynthetic processGO:1902680570.029
Mouse Worm
cellular pigmentationGO:0033059300.029
forebrain neuron developmentGO:002188470.029
multicellular organismal response to stressGO:003355520.028
Mouse
gland developmentGO:00487321430.028
organic acid metabolic processGO:0006082310.028
positive regulation of macromolecule metabolic processGO:0010604930.028
Mouse Worm
protein metabolic processGO:00195381830.028
modification dependent macromolecule catabolic processGO:004363230.027
proteolysis involved in cellular protein catabolic processGO:005160330.027
neuron projection developmentGO:00311751800.026
Mouse
response to biotic stimulusGO:0009607970.026
nucleobase containing compound biosynthetic processGO:00346542050.026
Human Mouse Worm
positive regulation of cellular component biogenesisGO:004408930.026
regulation of stem cell proliferationGO:007209120.026
regionalizationGO:00030022740.026
positive regulation of transportGO:005105020.025
gastrulationGO:00073692080.025
sensory perception of painGO:001923310.025
regulation of signal transductionGO:00099662250.025
embryo development ending in birth or egg hatchingGO:00097922710.025
Worm
sleepGO:003043110.025
retina development in camera type eyeGO:00600411460.024
forebrain cell migrationGO:002188510.024
neuron neuron synaptic transmissionGO:000727010.024
catechol containing compound biosynthetic processGO:000971320.024
Mouse
regulation of dendrite developmentGO:005077330.024
protein localization to nucleusGO:003450430.024
endocrine processGO:005088620.024
response to glucoseGO:000974930.023
peptidyl serine phosphorylationGO:001810510.023
cellular protein modification processGO:00064641000.023
deathGO:00162651210.023
Mouse
small molecule metabolic processGO:0044281770.023
regulation of glial cell differentiationGO:004568540.023
cellular macromolecule biosynthetic processGO:00346452240.023
Human Mouse Worm
extrinsic apoptotic signaling pathwayGO:009719130.023
centrosome cycleGO:000709810.023
growthGO:00400071740.022
regulation of apoptotic processGO:0042981980.022
Mouse
cellular component morphogenesisGO:00329893360.022
Mouse
epithelial cell differentiationGO:00308551160.022
negative regulation of neural precursor cell proliferationGO:200017810.022
neural tube patterningGO:0021532330.022
positive regulation of cell cycleGO:004578730.022
regulation of gonadotropin secretionGO:003227610.022
membrane invaginationGO:001032410.022
axon extensionGO:0048675450.021
oxoacid metabolic processGO:0043436310.021
positive regulation of metabolic processGO:00098931080.021
Mouse Worm
modification dependent protein catabolic processGO:001994130.021
digestive tract morphogenesisGO:00485462310.021
centrosome organizationGO:005129710.021
directional locomotionGO:003305810.021
taxisGO:00423301090.021
neuron projection guidanceGO:0097485860.021
negative regulation of catabolic processGO:000989530.021
developmental growthGO:00485891660.020
regulation of multicellular organism growthGO:004001440.020
regulation of reproductive processGO:200024140.020
Worm
response to carbohydrateGO:000974330.020
positive regulation of biosynthetic processGO:0009891680.020
Mouse Worm
developmental cell growthGO:0048588520.020
camera type eye morphogenesisGO:00485931080.020
mitochondrion organizationGO:000700540.020
sequestering of metal ionGO:005123830.020
regulation of transcription dna templatedGO:00063552130.020
Mouse Worm
protein targeting to nucleusGO:004474430.020
transportGO:00068102200.020
Fly
response to monosaccharideGO:003428430.020
protein importGO:001703830.020
guanosine containing compound catabolic processGO:190106920.020
regulation of dendrite morphogenesisGO:004881430.020
spinal cord developmentGO:0021510460.020
regulation of nucleotide catabolic processGO:003081120.020
regulation of cell morphogenesisGO:0022604420.020
sprouting angiogenesisGO:0002040530.019
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.019
positive regulation of apoptotic signaling pathwayGO:200123510.019
gtp metabolic processGO:004603940.019
ubiquitin dependent protein catabolic processGO:000651130.019
establishment of localizationGO:00512342440.019
Fly
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.019
regulation of extrinsic apoptotic signaling pathwayGO:200123630.019
renal system developmentGO:0072001940.019
cell morphogenesisGO:00009022890.019
Mouse
stem cell divisionGO:001714510.019
hypothalamus developmentGO:0021854140.019
axon developmentGO:00615641660.019
Mouse
single organism localizationGO:19025782250.019
Fly
regulation of catalytic activityGO:0050790550.019
Mouse
semicircular canal developmentGO:0060872240.019
interspecies interaction between organismsGO:004441940.019
positive regulation of cellular processGO:00485222010.019
Mouse Worm
protein import into nucleusGO:000660630.019
regulation of gtp catabolic processGO:003312420.019
tube morphogenesisGO:00352393490.018
mesoderm developmentGO:0007498880.018
regulation of synaptic plasticityGO:004816710.018
regulation of nucleoside metabolic processGO:000911820.018
vasculature developmentGO:00019442780.018
neural crest cell developmentGO:0014032620.018
nucleocytoplasmic transportGO:000691340.018
establishment of protein localization to organelleGO:007259440.018
axon guidanceGO:0007411860.018
regulation of nucleic acid templated transcriptionGO:19035062130.018
Mouse Worm
development of primary female sexual characteristicsGO:004654540.018
negative regulation of sequestering of calcium ionGO:005128340.018
cellular response to external stimulusGO:007149620.018
Human Mouse
negative regulation of cell communicationGO:0010648960.017
primary amino compound metabolic processGO:190116010.017
regulation of n methyl d aspartate selective glutamate receptor activityGO:200031010.017
regulation of protein complex assemblyGO:004325430.017
apoptotic processGO:00069151160.017
Mouse
skeletal system developmentGO:00015011810.017
positive regulation of macromolecule biosynthetic processGO:0010557590.017
Mouse Worm
regulation of epithelial cell proliferationGO:005067830.017
neuroblast proliferationGO:000740520.017
protein modification processGO:00362111000.017
regulation of neural precursor cell proliferationGO:200017730.016
regulation of axon guidanceGO:190266780.016
regulation of localizationGO:00328791040.016
nuclear importGO:005117030.016
positive regulation of rna metabolic processGO:0051254590.016
Mouse Worm
somitogenesisGO:0001756870.016
response to decreased oxygen levelsGO:0036293250.016
Mouse
cell fate commitmentGO:0045165990.016
response to hypoxiaGO:0001666250.016
Mouse
phosphate containing compound metabolic processGO:00067961080.016
neural crest cell differentiationGO:0014033720.016
response to external biotic stimulusGO:0043207970.016
microtubule organizing center organizationGO:003102310.016
negative regulation of protein phosphorylationGO:000193340.016
organelle organizationGO:00069962270.016
cell projection morphogenesisGO:00488582440.015
Mouse
endocrine hormone secretionGO:006098620.015
pancreatic d cell differentiationGO:000331120.015
symbiosis encompassing mutualism through parasitismGO:004440340.015
central nervous system neuron developmentGO:0021954290.015
multi organism processGO:00517041340.015
Worm
g protein coupled receptor signaling pathwayGO:0007186740.015
regulation of response to stimulusGO:00485832690.015
regulation of neurogenesisGO:0050767870.015
axonal defasciculationGO:000741420.015
dopamine metabolic processGO:004241720.015
Mouse
embryonic organ morphogenesisGO:00485622740.015
locomotory behaviorGO:0007626340.015
Mouse
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.015
cellular protein metabolic processGO:00442671290.015
positive regulation of immune effector processGO:000269930.015
regulation of oligodendrocyte differentiationGO:004871310.015
spinal cord motor neuron differentiationGO:0021522260.015
spindle assemblyGO:005122520.015
tyrosine phosphorylation of stat proteinGO:000726010.015
multi organism cellular processGO:004476420.015
ear morphogenesisGO:0042471640.014
type b pancreatic cell developmentGO:000332340.014
response to corticosteroidGO:003196010.014
regulation of cellular response to oxidative stressGO:190040720.014
digestive tract developmentGO:00485652650.014
gtp catabolic processGO:000618420.014
heart developmentGO:00075073130.014
regulation of gtpase activityGO:004308720.014
regulation of cell activationGO:005086510.014
regulation of lipid transportGO:003236840.014
regulation of cell developmentGO:00602841000.014
regulation of cell shapeGO:000836010.014
rostrocaudal neural tube patterningGO:0021903290.014
negative regulation of signalingGO:0023057960.013
negative regulation of developmental processGO:0051093650.013
negative regulation of cellular metabolic processGO:0031324770.013
axonogenesisGO:00074091520.013
Mouse
meiotic nuclear divisionGO:000712640.013
regulation of tissue remodelingGO:003410320.013
tissue remodelingGO:004877140.013
regulation of transporter activityGO:003240920.013
hypothalamus cell differentiationGO:002197940.013
glial cell fate specificationGO:002178040.013
oligodendrocyte differentiationGO:0048709230.013
chemotaxisGO:00069351040.013
negative regulation of protein kinase activityGO:000646940.013
establishment of synaptic vesicle localizationGO:009748010.013
ventral spinal cord developmentGO:0021517350.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.013
Mouse Worm
photoreceptor cell differentiationGO:0046530550.013
anterior posterior pattern specificationGO:00099521520.013
cell projection organizationGO:00300302840.013
Mouse
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.013
peptidyl serine modificationGO:001820920.013
convergent extensionGO:00600261180.013
autophagyGO:000691440.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
Mouse
negative regulation of metabolic processGO:0009892860.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
proteasomal protein catabolic processGO:001049820.013
cellular amino acid biosynthetic processGO:000865220.013
response to drugGO:004249330.013
regulation of metal ion transportGO:001095940.012
regulation of cell motilityGO:2000145460.012
positive regulation of catabolic processGO:000989640.012
negative regulation of protein complex assemblyGO:003133310.012
single organism nuclear importGO:190259330.012
actomyosin structure organizationGO:0031032530.012
regulation of endocrine processGO:004406020.012
neural tube developmentGO:0021915620.012
kidney developmentGO:0001822920.012
response to glucocorticoidGO:005138410.012
positive regulation of gene expressionGO:0010628710.012
Mouse Worm
regulation of sequestering of calcium ionGO:005128240.012
brain morphogenesisGO:0048854180.012
optokinetic behaviorGO:000763490.012
protein acylationGO:004354330.012
regulation of blood vessel sizeGO:005088020.012
serotonin metabolic processGO:004242810.012
response to bacteriumGO:0009617580.012
positive regulation of multi organism processGO:004390230.012
positive regulation of response to stimulusGO:0048584800.012
regulation of multicellular organismal developmentGO:20000262230.012
Fly
negative regulation of leukocyte differentiationGO:190210610.012
female sex differentiationGO:004666040.011
mesenchymal cell differentiationGO:0048762870.011
urogenital system developmentGO:0001655970.011
intracellular signal transductionGO:0035556850.011
positive regulation of nucleotide catabolic processGO:003081310.011
response to uvGO:000941130.011
negative regulation of macromolecule metabolic processGO:0010605760.011
response to hydrogen peroxideGO:004254230.011
cell fate specificationGO:0001708680.011
cellular response to oxygen levelsGO:007145310.011
convergent extension involved in gastrulationGO:0060027710.011
antimicrobial humoral responseGO:001973020.011
thermosensory behaviorGO:004004010.011
response to oxygen levelsGO:0070482250.011
Mouse
regulation of neuron projection developmentGO:0010975400.011
regulation of purine nucleotide catabolic processGO:003312120.011
regulation of bindingGO:005109830.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
blood vessel developmentGO:00015682460.011
regulation of tube sizeGO:003515020.011
interaction with hostGO:005170140.011
morphogenesis of an epitheliumGO:00020093330.011
regulation of protein metabolic processGO:0051246560.011
fertilizationGO:000956630.011
cellular component assemblyGO:00226071700.011
positive regulation of secretionGO:005104710.011
cellular response to hypoxiaGO:007145610.011
blood vessel morphogenesisGO:00485142160.011
fatty acid catabolic processGO:000906210.011
cellular component biogenesisGO:00440851780.011
regulation of calcium ion transportGO:005192420.011
cellular response to reactive oxygen speciesGO:003461420.011
regulation of organ growthGO:004662030.011
stem cell developmentGO:0048864820.011
blood circulationGO:0008015870.011
regulation of ras gtpase activityGO:003231820.011
lipid storageGO:001991510.010
receptor internalizationGO:003162320.010
lipid catabolic processGO:001604240.010
sequestering of calcium ionGO:005120830.010
tyrosine phosphorylation of stat3 proteinGO:004250310.010
somatic stem cell maintenanceGO:003501910.010
regulation of establishment of protein localizationGO:007020140.010
liver developmentGO:0001889960.010
regulation of protein ubiquitinationGO:003139630.010
protein acetylationGO:000647320.010
positive regulation of cellular catabolic processGO:003133130.010
response to oxygen containing compoundGO:1901700550.010

nr4a2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.024
disease of anatomical entityDOID:700.018
central nervous system diseaseDOID:33100.011
synucleinopathyDOID:005089000.011
neurodegenerative diseaseDOID:128900.011
parkinson s diseaseDOID:1433000.011
nervous system diseaseDOID:86300.011
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011