Danio rerio

112 known processes

htt

huntingtin

(Aliases: ZHD,hd)

htt biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.161
embryonic organ developmentGO:00485683810.159
response to alkaloidGO:004327920.085
immune system developmentGO:00025201910.072
agingGO:000756820.065
Mouse
signal transductionGO:00071654550.059
regionalizationGO:00030022740.057
Mouse
embryonic skeletal system developmentGO:0048706970.053
digestive tract developmentGO:00485652650.053
Mouse
meiotic nuclear divisionGO:000712640.051
embryonic organ morphogenesisGO:00485622740.050
cellular response to extracellular stimulusGO:003166820.049
multicellular organism growthGO:003526440.048
organic substance biosynthetic processGO:19015762890.046
Mouse
establishment of localizationGO:00512342440.044
Mouse
extracellular structure organizationGO:0043062270.043
negative regulation of nucleocytoplasmic transportGO:004682320.042
regulation of multicellular organism growthGO:004001440.039
compound eye developmentGO:004874920.038
organonitrogen compound metabolic processGO:1901564740.038
Mouse
meiotic chromosome segregationGO:004513230.036
cellular macromolecule biosynthetic processGO:00346452240.036
embryonic skeletal system morphogenesisGO:0048704930.035
maintenance of locationGO:005123540.033
nitrogen compound metabolic processGO:00068073190.032
Mouse
regulation of protein catabolic processGO:004217610.031
regulation of biological qualityGO:00650082630.031
extracellular matrix organizationGO:0030198270.031
peptidyl serine phosphorylationGO:001810510.030
rna transportGO:005065820.030
cellular response to starvationGO:000926710.030
meiotic cell cycle processGO:190304630.029
cellular nitrogen compound metabolic processGO:00346412900.028
Mouse
protein metabolic processGO:00195381830.028
negative regulation of defense responseGO:003134820.027
cortical cytoskeleton organizationGO:003086510.027
phagocytosisGO:000690930.027
cell surface receptor signaling pathwayGO:00071663250.026
synaptic growth at neuromuscular junctionGO:005112420.026
erk1 and erk2 cascadeGO:007037140.026
mitochondrion organizationGO:000700540.026
Mouse
rna localizationGO:000640340.026
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
system processGO:00030081850.026
Mouse
embryonic cranial skeleton morphogenesisGO:0048701900.026
erythrocyte homeostasisGO:0034101550.025
positive regulation of notch signaling pathwayGO:004574730.025
regulation of bindingGO:005109830.025
microtubule cytoskeleton organization involved in mitosisGO:190285010.025
cellular protein catabolic processGO:004425740.025
cellular biosynthetic processGO:00442492860.024
Mouse
small molecule metabolic processGO:0044281770.024
Mouse
regulation of circadian rhythmGO:004275240.024
cellular response to external stimulusGO:007149620.024
regulation of synapse organizationGO:005080730.023
cellular response to nutrient levelsGO:003166920.023
regulation of peptidyl tyrosine phosphorylationGO:005073010.023
dorsal ventral pattern formationGO:00099531250.023
regulation of protein complex assemblyGO:004325430.023
nucleoside monophosphate catabolic processGO:000912540.023
erythrocyte differentiationGO:0030218540.023
nucleic acid transportGO:005065720.022
cartilage developmentGO:0051216960.022
regulation of neurological system processGO:003164420.022
regulation of erk1 and erk2 cascadeGO:007037240.022
spindle assemblyGO:005122520.022
hematopoietic or lymphoid organ developmentGO:00485341910.022
carbohydrate homeostasisGO:003350010.021
inner ear developmentGO:00488391260.021
cell substrate adhesionGO:003158940.021
myeloid cell homeostasisGO:0002262560.021
adult behaviorGO:003053420.021
protein targeting to nucleusGO:004474430.021
Mouse
determination of bilateral symmetryGO:00098552040.021
peptidyl serine modificationGO:001820920.021
somatic muscle developmentGO:000752540.021
positive regulation of cellular catabolic processGO:003133130.020
synaptic target recognitionGO:000803910.020
lipid storageGO:001991510.020
extrinsic apoptotic signaling pathwayGO:009719130.020
regulation of cytoplasmic transportGO:190364940.020
response to uvGO:000941130.020
myeloid cell developmentGO:0061515320.020
centrosome organizationGO:005129710.020
protein import into nucleusGO:000660630.020
Mouse
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.020
stem cell maintenanceGO:001982740.020
gtp catabolic processGO:000618420.020
cellular modified amino acid metabolic processGO:000657530.020
Mouse
organic acid metabolic processGO:0006082310.020
Mouse
positive regulation of nucleoside metabolic processGO:004597910.020
erythrocyte developmentGO:0048821240.020
protein localization to nucleusGO:003450430.019
Mouse
embryo development ending in birth or egg hatchingGO:00097922710.019
cell morphogenesisGO:00009022890.019
skeletal system developmentGO:00015011810.019
negative regulation of cytoplasmic transportGO:190365020.019
mitotic dna integrity checkpointGO:004477440.019
regulation of molecular functionGO:0065009700.019
regulation of synapse assemblyGO:005196330.019
regulation of protein ubiquitinationGO:003139630.019
ribosomal small subunit biogenesisGO:004227420.019
cell morphogenesis involved in differentiationGO:00009041950.019
cell matrix adhesionGO:000716040.018
biosynthetic processGO:00090582940.018
Mouse
sensory organ developmentGO:00074233930.018
cartilage morphogenesisGO:0060536130.018
generation of neuronsGO:00486993850.018
regulation of cell communicationGO:00106462320.018
positive regulation of catabolic processGO:000989640.018
er to golgi vesicle mediated transportGO:000688810.018
Mouse
wnt signaling pathwayGO:0016055800.018
regulation of transmembrane transporter activityGO:002289820.018
regulation of response to stimulusGO:00485832690.017
sensory perception of mechanical stimulusGO:0050954160.017
regulation of establishment of protein localizationGO:007020140.017
proteolysis involved in cellular protein catabolic processGO:005160330.017
axon developmentGO:00615641660.017
locomotionGO:00400113130.017
cellular macromolecule metabolic processGO:00442603910.017
establishment of rna localizationGO:005123630.017
regulation of cell activationGO:005086510.017
ear developmentGO:00435831270.017
nuclear transportGO:005116940.017
Mouse
protein acetylationGO:000647320.017
response to stressGO:00069502630.017
regulation of carbohydrate metabolic processGO:000610940.017
negative regulation of protein kinase activityGO:000646940.017
immune system processGO:00023762410.017
regulation of cellular amino acid metabolic processGO:000652100.017
ribonucleoside monophosphate catabolic processGO:000915840.016
myeloid cell differentiationGO:0030099860.016
cellular amine metabolic processGO:004410620.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
cortical actin cytoskeleton organizationGO:003086610.016
protein modification processGO:00362111000.016
regulation of protein bindingGO:004339330.016
locomotor rhythmGO:004547530.016
response to chemicalGO:00422213200.016
Mouse
regulation of protein transportGO:005122330.016
establishment of synaptic vesicle localizationGO:009748010.016
neuron projection morphogenesisGO:00488121610.016
gtp metabolic processGO:004603940.016
response to organic substanceGO:00100331530.016
nucleobase containing compound biosynthetic processGO:00346542050.016
regulation of protein import into nucleusGO:004230620.016
ameboidal type cell migrationGO:00016671430.016
organism emergence from protective structureGO:007168440.016
cytokinesisGO:000091030.016
mesenchymal cell differentiationGO:0048762870.016
digestive system developmentGO:00551232890.016
Mouse
organelle organizationGO:00069962270.016
Mouse
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
positive regulation of dna metabolic processGO:005105410.016
membrane invaginationGO:001032410.015
microtubule organizing center organizationGO:003102310.015
negative regulation of kinase activityGO:003367340.015
negative regulation of intracellular transportGO:003238730.015
actin filament based movementGO:003004810.015
cellular component biogenesisGO:00440851780.015
protein polymerizationGO:005125840.015
macromolecule biosynthetic processGO:00090592270.015
post embryonic organ developmentGO:004856940.015
regulation of ion transmembrane transporter activityGO:003241220.015
synaptic vesicle localizationGO:009747910.015
cardiac atrium developmentGO:000323040.015
response to hydrogen peroxideGO:004254230.015
positive regulation of transportGO:005105020.015
regulation of protein modification by small protein conjugation or removalGO:190332030.015
protein dephosphorylationGO:000647030.015
phagocytosis engulfmentGO:000691110.015
amine metabolic processGO:000930820.015
neurotransmitter secretionGO:000726920.015
exocytosisGO:000688710.015
negative regulation of tor signalingGO:003200720.015
morphogenesis of an epitheliumGO:00020093330.014
meiotic spindle organizationGO:000021210.014
autophagyGO:000691440.014
hatchingGO:003518840.014
positive regulation of cell divisionGO:005178120.014
chordate embryonic developmentGO:00430092710.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
b cell activationGO:004211320.014
heart loopingGO:0001947940.014
negative regulation of ras protein signal transductionGO:004658010.014
cellular component disassemblyGO:002241110.014
lateral line developmentGO:0048882660.014
internal protein amino acid acetylationGO:000647520.014
central nervous system developmentGO:00074173870.014
single organism localizationGO:19025782250.014
Mouse
negative regulation of protein phosphorylationGO:000193340.014
defense responseGO:0006952470.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
gastrulationGO:00073692080.014
Mouse
proteasomal protein catabolic processGO:001049820.014
regulation of jak stat cascadeGO:004642530.014
spermatid developmentGO:000728620.014
positive regulation of erk1 and erk2 cascadeGO:007037420.014
protein polyubiquitinationGO:000020940.014
single organism metabolic processGO:00447102170.014
Mouse
oxoacid metabolic processGO:0043436310.013
Mouse
regulation of response to extracellular stimulusGO:003210410.013
lipid catabolic processGO:001604240.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
regulation of cellular amine metabolic processGO:003323800.013
regulation of signal transductionGO:00099662250.013
b cell differentiationGO:003018310.013
neuron differentiationGO:00301823530.013
digestive tract morphogenesisGO:00485462310.013
Mouse
guanosine containing compound metabolic processGO:190106840.013
positive regulation of map kinase activityGO:004340630.013
nucleic acid templated transcriptionGO:00976591810.013
glucose homeostasisGO:004259310.013
glycoprotein metabolic processGO:0009100230.013
circadian sleep wake cycleGO:004274520.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
negative regulation of map kinase activityGO:004340720.013
cellular amino acid metabolic processGO:000652070.013
Mouse
g2 dna damage checkpointGO:003157230.013
response to carbohydrateGO:000974330.013
somitogenesisGO:0001756870.013
cell projection morphogenesisGO:00488582440.012
positive regulation of epithelial cell migrationGO:001063420.012
heart morphogenesisGO:00030071560.012
apoptotic process involved in developmentGO:190274220.012
cell growthGO:0016049570.012
heterocycle biosynthetic processGO:00181302150.012
Mouse
neuron developmentGO:00486662620.012
positive regulation of immune effector processGO:000269930.012
negative regulation of protein import into nucleusGO:004230820.012
hormone secretionGO:004687920.012
Mouse
meiosis iiGO:000713510.012
positive regulation of canonical wnt signaling pathwayGO:009026340.012
pigment cell differentiationGO:0050931380.012
negative chemotaxisGO:005091910.012
positive regulation of cellular component biogenesisGO:004408930.012
muscle structure developmentGO:00610611960.012
circadian sleep wake cycle sleepGO:005080210.012
negative regulation of immune responseGO:005077720.012
development of primary female sexual characteristicsGO:004654540.012
neurotransmitter transportGO:000683620.012
small gtpase mediated signal transductionGO:000726480.012
hemopoiesisGO:00300971830.012
forebrain developmentGO:0030900960.012
Mouse
regulation of locomotionGO:0040012550.012
positive regulation of cell activationGO:005086710.012
cell part morphogenesisGO:00329902460.012
response to hexoseGO:000974630.012
homeostasis of number of cellsGO:0048872620.012
erythrocyte maturationGO:004324980.011
taxisGO:00423301090.011
response to nutrientGO:000758430.011
regulation of nucleocytoplasmic transportGO:004682220.011
neural crest cell differentiationGO:0014033720.011
regulation of nitrogen compound metabolic processGO:00511712510.011
vasculature developmentGO:00019442780.011
regulation of nucleic acid templated transcriptionGO:19035062130.011
negative regulation of small gtpase mediated signal transductionGO:005105810.011
pole plasm assemblyGO:000731540.011
localization of cellGO:00516742440.011
negative regulation of intracellular protein transportGO:009031730.011
nucleobase containing compound transportGO:001593120.011
positive regulation of cell cycleGO:004578730.011
response to woundingGO:00096111160.011
rna modificationGO:000945120.011
rna metabolic processGO:00160702190.011
brain developmentGO:00074202930.011
Mouse
periodic partitioningGO:000736510.011
cellular protein metabolic processGO:00442671290.011
protein acylationGO:004354330.011
regulation of transporter activityGO:003240920.011
centrosome cycleGO:000709810.011
response to biotic stimulusGO:0009607970.011
epithelial cell morphogenesisGO:000338220.011
sensory perception of smellGO:000760820.011
cardiac atrium morphogenesisGO:000320920.011
cellular aromatic compound metabolic processGO:00067252950.011
leukocyte differentiationGO:0002521250.011
regulation of rna biosynthetic processGO:20011412130.011
specification of symmetryGO:00097992040.011
nucleocytoplasmic transportGO:000691340.011
Mouse
activation of mapk activityGO:000018730.011
convergent extension involved in gastrulationGO:0060027710.011
protein importGO:001703830.011
Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.011
Mouse
negative regulation of protein serine threonine kinase activityGO:007190120.011
atp catabolic processGO:000620040.010
regulation of intracellular protein transportGO:003315730.010
regulation of autophagyGO:001050630.010
determination of intestine left right asymmetryGO:007190820.010
primitive hemopoiesisGO:0060215270.010
gene expressionGO:00104672520.010
cellular amide metabolic processGO:004360340.010
Mouse
response to external biotic stimulusGO:0043207970.010
chondroitin sulfate proteoglycan metabolic processGO:005065480.010
tissue remodelingGO:004877140.010
mesenchymal cell developmentGO:0014031780.010
negative regulation of multi organism processGO:004390130.010
heterocycle metabolic processGO:00464832900.010
Mouse
regulation of cellular carbohydrate metabolic processGO:001067540.010
positive regulation of gtpase activityGO:004354710.010
regulation of nucleotide catabolic processGO:003081120.010
cellular ketone metabolic processGO:0042180110.010
chemotaxisGO:00069351040.010

htt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.029
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
sensory system diseaseDOID:005015500.013
nervous system diseaseDOID:86300.013
eye and adnexa diseaseDOID:149200.013
organ system cancerDOID:005068600.012