Danio rerio

0 known processes

slc6a8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

(Aliases: chot1)

slc6a8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic organ developmentGO:00485683810.574
heart developmentGO:00075073130.486
regulation of cell projection organizationGO:0031344440.279
regulation of signalingGO:00230512350.259
Zebrafish
visual perceptionGO:0007601170.213
heart morphogenesisGO:00030071560.211
signal transductionGO:00071654550.199
ribonucleotide biosynthetic processGO:0009260200.171
cell migration involved in heart developmentGO:0060973220.169
regulation of cgmp metabolic processGO:003082360.168
negative regulation of response to cytokine stimulusGO:006076120.149
cell surface receptor signaling pathwayGO:00071663250.148
negative regulation of cytokine mediated signaling pathwayGO:000196020.142
outflow tract morphogenesisGO:000315110.129
maintenance of locationGO:005123540.128
cardioblast migration to the midline involved in heart field formationGO:006097570.128
single organism metabolic processGO:00447102170.127
glial cell migrationGO:000834730.125
morphogenesis of an epitheliumGO:00020093330.114
retina development in camera type eyeGO:00600411460.112
cellular modified amino acid metabolic processGO:000657530.110
regionalizationGO:00030022740.110
central nervous system developmentGO:00074173870.104
ribose phosphate biosynthetic processGO:0046390200.100
embryonic heart tube developmentGO:00350501330.095
regulation of synapse organizationGO:005080730.095
embryonic organ morphogenesisGO:00485622740.093
ribose phosphate metabolic processGO:0019693270.092
retina layer formationGO:0010842240.092
negative regulation of cellular processGO:00485232830.091
blood vessel morphogenesisGO:00485142160.089
regulation of cyclic nucleotide metabolic processGO:0030799150.085
regulation of cell developmentGO:00602841000.084
negative regulation of cell differentiationGO:0045596460.083
localization of cellGO:00516742440.083
digestive system developmentGO:00551232890.082
ameboidal type cell migrationGO:00016671430.082
regulation of cell morphogenesisGO:0022604420.082
response to ketoneGO:190165410.080
fertilizationGO:000956630.078
convergent extension involved in organogenesisGO:0060029100.078
sympathetic nervous system developmentGO:004848530.077
generation of neuronsGO:00486993850.074
gland developmentGO:00487321430.074
positive regulation of biological processGO:00485182530.073
positive regulation of nervous system developmentGO:0051962250.073
regulation of cell communicationGO:00106462320.073
Zebrafish
biosynthetic processGO:00090582940.068
axon ensheathment in central nervous systemGO:003229120.068
cell migrationGO:00164772370.066
mesoderm morphogenesisGO:0048332510.066
response to chemicalGO:00422213200.064
epithelial cell migrationGO:0010631250.063
negative regulation of cell growthGO:003030870.063
regulation of biological qualityGO:00650082630.062
Zebrafish
single organism biosynthetic processGO:0044711710.061
digestive tract mesoderm developmentGO:000750210.061
photoreceptor cell differentiationGO:0046530550.061
small molecule metabolic processGO:0044281770.060
negative regulation of cell communicationGO:0010648960.059
response to vitaminGO:003327330.057
gastrulationGO:00073692080.057
cellular response to radiationGO:007147840.056
locomotionGO:00400113130.056
cell substrate adhesionGO:003158940.054
blood vessel developmentGO:00015682460.054
neural crest cell migrationGO:0001755420.054
gene expressionGO:00104672520.053
regulation of synapse assemblyGO:005196330.052
cellular lipid catabolic processGO:004424230.052
regulation of response to stimulusGO:00485832690.051
purine nucleotide biosynthetic processGO:0006164200.051
lateral inhibitionGO:004633110.050
multicellular organism growthGO:003526440.049
organonitrogen compound metabolic processGO:1901564740.048
regulation of signal transductionGO:00099662250.048
negative regulation of synapse assemblyGO:005196420.047
brain developmentGO:00074202930.047
tube morphogenesisGO:00352393490.047
negative regulation of biological processGO:00485193040.046
response to organic substanceGO:00100331530.046
regulation of response to cytokine stimulusGO:006075930.046
purine containing compound biosynthetic processGO:0072522200.046
positive regulation of synapse assemblyGO:005196510.045
axon midline choice point recognitionGO:001619940.045
positive regulation of cellular metabolic processGO:0031325940.045
negative regulation of chemotaxisGO:005092240.045
small gtpase mediated signal transductionGO:000726480.044
digestive tract morphogenesisGO:00485462310.044
cellular biosynthetic processGO:00442492860.044
negative regulation of nervous system developmentGO:0051961220.044
camera type eye developmentGO:00430102220.043
carboxylic acid metabolic processGO:0019752220.043
regulation of developmental processGO:00507932470.043
central nervous system neuron axonogenesisGO:0021955180.043
regulation of macromolecule metabolic processGO:00602553170.042
neuron differentiationGO:00301823530.042
negative regulation of developmental processGO:0051093650.041
heart formationGO:0060914130.041
regulation of inflammatory responseGO:005072720.041
cell migration involved in heart formationGO:0060974100.040
regulation of bindingGO:005109830.039
response to nutrientGO:000758430.039
intracellular signal transductionGO:0035556850.039
negative regulation of innate immune responseGO:004582420.038
neural retina developmentGO:0003407490.037
response to amino acidGO:004320020.037
neuron projection morphogenesisGO:00488121610.037
positive regulation of cell adhesionGO:004578510.037
cranial ganglion developmentGO:006155030.037
cell migration to the midline involved in heart developmentGO:0003318120.036
gliogenesisGO:0042063450.035
retina morphogenesis in camera type eyeGO:0060042790.035
positive regulation of cyclic nucleotide biosynthetic processGO:003080480.035
cellular response to oxygen levelsGO:007145310.035
negative regulation of cell developmentGO:0010721260.034
digestive tract developmentGO:00485652650.034
cardiac cell developmentGO:0055006210.034
neuron developmentGO:00486662620.034
cytokinesisGO:000091030.033
response to steroid hormoneGO:0048545350.033
pole plasm assemblyGO:000731540.033
response to corticosteroidGO:003196010.033
cellular macromolecule metabolic processGO:00442603910.033
protein alkylationGO:0008213130.033
positive regulation of cellular processGO:00485222010.033
lipid homeostasisGO:005508830.032
eye developmentGO:00016542770.032
alpha amino acid metabolic processGO:190160530.032
response to external stimulusGO:00096052640.032
nitrogen compound metabolic processGO:00068073190.031
cgmp metabolic processGO:004606870.031
regulation of protein metabolic processGO:0051246560.031
nucleoside phosphate biosynthetic processGO:1901293210.031
transportGO:00068102200.030
Zebrafish
negative regulation of signal transductionGO:0009968940.030
regulation of primary metabolic processGO:00800903110.030
camera type eye photoreceptor cell differentiationGO:0060219190.030
regulation of interferon gamma mediated signaling pathwayGO:006033410.030
cellular response to nutrient levelsGO:003166920.029
response to hormoneGO:0009725480.029
heart loopingGO:0001947940.029
cardioblast migrationGO:000326070.029
regulation of cytokine mediated signaling pathwayGO:000195930.029
anterior posterior pattern specificationGO:00099521520.029
light adaptionGO:003636710.028
cellular component disassemblyGO:002241110.028
response to glucocorticoidGO:005138410.027
sensory organ developmentGO:00074233930.027
regulation of neuron differentiationGO:0045664560.027
myelin assemblyGO:003228810.027
hydrogen peroxide metabolic processGO:004274320.027
cellular component movementGO:00069283350.027
regulation of cellular component organizationGO:0051128860.027
cellular component morphogenesisGO:00329893360.026
guanosine containing compound catabolic processGO:190106920.026
negative regulation of signalingGO:0023057960.026
agingGO:000756820.026
cell projection morphogenesisGO:00488582440.026
cellular amino acid metabolic processGO:000652070.026
positive regulation of cgmp biosynthetic processGO:003082860.026
golgi vesicle transportGO:004819330.026
forebrain cell migrationGO:002188510.026
dopamine metabolic processGO:004241720.026
cellular response to extracellular stimulusGO:003166820.026
response to drugGO:004249330.026
positive regulation of metabolic processGO:00098931080.025
hormone transportGO:000991420.025
chordate embryonic developmentGO:00430092710.025
digestive system processGO:002260090.025
maternal determination of anterior posterior axis embryoGO:000835840.025
atrioventricular valve developmentGO:0003171110.025
developmental growth involved in morphogenesisGO:0060560860.025
organic acid metabolic processGO:0006082310.025
retinal cone cell differentiationGO:0042670120.024
mesodermal cell migrationGO:0008078120.024
single organism localizationGO:19025782250.024
Zebrafish
protein localizationGO:0008104400.024
stem cell maintenanceGO:001982740.024
establishment of synaptic vesicle localizationGO:009748010.024
immune responseGO:0006955280.024
lipoprotein biosynthetic processGO:004215830.023
olfactory lobe developmentGO:002198840.023
glucose homeostasisGO:004259310.023
cellular amino acid biosynthetic processGO:000865220.023
embryonic cranial skeleton morphogenesisGO:0048701900.023
cell projection organizationGO:00300302840.023
regulation of localizationGO:00328791040.023
inflammatory responseGO:000695480.023
lipid catabolic processGO:001604240.022
response to estrogenGO:0043627270.022
regulation of cell differentiationGO:00455951420.022
response to lipidGO:0033993600.022
embryo development ending in birth or egg hatchingGO:00097922710.021
histone h3 k4 methylationGO:005156820.021
single organismal cell cell adhesionGO:0016337290.021
regulation of neurogenesisGO:0050767870.021
positive regulation of nitrogen compound metabolic processGO:0051173690.021
cellular nitrogen compound metabolic processGO:00346412900.021
developmental cell growthGO:0048588520.021
central nervous system neuron differentiationGO:0021953740.021
negative regulation of protein kinase activityGO:000646940.021
cellular response to steroid hormone stimulusGO:0071383310.021
phosphate containing compound metabolic processGO:00067961080.020
organic substance transportGO:0071702580.020
Zebrafish
regulation of molecular functionGO:0065009700.020
oxoacid metabolic processGO:0043436310.020
endosomal transportGO:001619720.020
regulation of biosynthetic processGO:00098892500.020
positive regulation of cellular component biogenesisGO:004408930.020
positive regulation of cell cycleGO:004578730.020
positive regulation of neurogenesisGO:0050769240.020
response to light intensityGO:000964210.020
negative regulation of kinase activityGO:003367340.020
long chain fatty acid transportGO:001590910.019
programmed cell deathGO:00125011190.019
organonitrogen compound biosynthetic processGO:1901566470.019
regulation of lyase activityGO:0051339120.019
neuron neuron synaptic transmissionGO:000727010.019
Zebrafish
regulation of cellular metabolic processGO:00313233200.019
negative regulation of defense responseGO:003134820.019
purine ribonucleotide biosynthetic processGO:0009152200.019
system processGO:00030081850.019
regulation of multicellular organismal developmentGO:20000262230.019
response to carbohydrateGO:000974330.019
regulation of guanylate cyclase activityGO:003128260.019
ventricular cardiac muscle tissue developmentGO:000322930.019
dna biosynthetic processGO:007189730.019
regulation of neuron migrationGO:200122220.019
ectodermal placode formationGO:0060788260.018
response to stressGO:00069502630.018
proximal distal pattern formationGO:000995410.018
positive regulation of purine nucleotide biosynthetic processGO:190037380.018
acylglycerol homeostasisGO:005509020.018
regulation of stem cell differentiationGO:200073640.018
photoreceptor cell fate commitmentGO:004655210.018
post golgi vesicle mediated transportGO:000689210.018
alcohol biosynthetic processGO:004616520.018
phototransductionGO:000760220.018
stem cell proliferationGO:007208940.018
single organism transportGO:00447652060.018
Zebrafish
cytoplasm organizationGO:000702840.017
regulation of response to interferon gammaGO:006033010.017
regulation of glial cell differentiationGO:004568540.017
cellular response to external stimulusGO:007149620.017
sleepGO:003043110.017
cell projection assemblyGO:0030031640.017
phosphorus metabolic processGO:00067931090.017
photoreceptor cell developmentGO:0042461400.017
enzyme linked receptor protein signaling pathwayGO:00071671060.017
phototransduction visible lightGO:000760320.016
protein metabolic processGO:00195381830.016
nucleobase containing compound metabolic processGO:00061392740.016
neurotransmitter transportGO:000683620.016
multicellular organismal signalingGO:0035637220.016
regulation of stem cell proliferationGO:007209120.016
cell morphogenesisGO:00009022890.016
central nervous system myelin formationGO:003228910.016
positive regulation of cellular catabolic processGO:003133130.016
negative regulation of neuron projection developmentGO:001097790.016
cellular component biogenesisGO:00440851780.016
defense responseGO:0006952470.016
nucleobase containing compound biosynthetic processGO:00346542050.016
development of primary female sexual characteristicsGO:004654540.016
hindbrain developmentGO:0030902910.016
regulation of phosphate metabolic processGO:0019220430.016
regulation of fatty acid metabolic processGO:001921710.016
synaptic vesicle localizationGO:009747910.016
organ formationGO:0048645170.016
axon developmentGO:00615641660.016
regulation of reproductive processGO:200024140.015
protein complex disassemblyGO:004324110.015
hormone secretionGO:004687920.015
chloride transmembrane transportGO:190247640.015
cell motilityGO:00488702440.015
regulation of carbohydrate metabolic processGO:000610940.015
glial cell differentiationGO:0010001420.015
intracellular mrna localizationGO:000829810.015
single organism cell adhesionGO:0098602290.015
organophosphate biosynthetic processGO:0090407230.015
eye morphogenesisGO:00485921440.015
formation of primary germ layerGO:0001704620.015
regulation of anatomical structure morphogenesisGO:00226031300.015
growthGO:00400071740.015
olfactory bulb developmentGO:002177240.015
regulation of neurotransmitter secretionGO:004692810.015
positive regulation of purine nucleotide metabolic processGO:190054490.015
polarized epithelial cell differentiationGO:003085940.015
organic cyclic compound biosynthetic processGO:19013622230.015
response to foodGO:003209410.015
action potentialGO:0001508190.015
establishment of epithelial cell polarityGO:009016220.015
blood circulationGO:0008015870.015
regulation of metabolic processGO:00192223590.015
neural tube patterningGO:0021532330.014
synaptic vesicle transportGO:004848910.014
mesoderm formationGO:0001707430.014
neurotransmitter secretionGO:000726920.014
single organism organelle organizationGO:19025891990.014
negative regulation of protein phosphorylationGO:000193340.014
negative regulation of multicellular organismal processGO:0051241690.014
regulation of phosphorus metabolic processGO:0051174430.014
neural crest cell developmentGO:0014032620.014
camera type eye morphogenesisGO:00485931080.014
carbohydrate homeostasisGO:003350010.014
anterior posterior axis specificationGO:0009948200.014
immune system processGO:00023762410.014
axonal defasciculationGO:000741420.014
negative regulation of axon guidanceGO:190266810.014
apoptotic processGO:00069151160.014
determination of bilateral symmetryGO:00098552040.014
regulation of nervous system developmentGO:0051960900.014
guanosine containing compound metabolic processGO:190106840.013
establishment of localizationGO:00512342440.013
Zebrafish
eye photoreceptor cell differentiationGO:0001754450.013
protein modification by small protein removalGO:007064610.013
dna alkylationGO:000630580.013
central nervous system myelinationGO:002201020.013
negative regulation of immune responseGO:005077720.013
intracellular receptor signaling pathwayGO:0030522300.013
embryonic heart tube morphogenesisGO:00031431080.013
cell deathGO:00082191210.013
negative regulation of cell projection organizationGO:003134590.013
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.013
cyclic purine nucleotide metabolic processGO:0052652180.013
intrahepatic bile duct developmentGO:0035622110.013
circadian sleep wake cycle sleepGO:005080210.013
hatching gland developmentGO:004878530.013
cgmp biosynthetic processGO:000618270.013
cellular component assemblyGO:00226071700.013
response to biotic stimulusGO:0009607970.013
response to light stimulusGO:0009416460.013
calcium mediated signalingGO:001972220.013
positive regulation of cell morphogenesis involved in differentiationGO:001077060.013
forebrain developmentGO:0030900960.013
regulation of apoptotic processGO:0042981980.013
axonogenesisGO:00074091520.013
transmission of nerve impulseGO:0019226190.013
female sex differentiationGO:004666040.013
head developmentGO:00603223030.013
regulation of membrane potentialGO:0042391230.012
Zebrafish
response to inorganic substanceGO:0010035380.012
histone methylationGO:0016571130.012
segmentationGO:0035282970.012
convergent extensionGO:00600261180.012
multi organism processGO:00517041340.012
determination of heart left right asymmetryGO:00613711170.012
positive regulation of translationGO:004572710.012
retinal cone cell developmentGO:004654980.012
negative regulation of programmed cell deathGO:0043069580.012
fatty acid transportGO:001590810.012
regulation of neuron projection developmentGO:0010975400.012
negative regulation of response to stimulusGO:00485851040.012
cellular response to light stimulusGO:007148240.012
negative regulation of axon extension involved in axon guidanceGO:004884310.012
neuroblast proliferationGO:000740520.012
negative regulation of behaviorGO:004852160.012
pancreas developmentGO:0031016840.012
regulation of metal ion transportGO:001095940.012
endocardial progenitor cell migration to the midline involved in heart field formationGO:000326240.012
regulation of multicellular organism growthGO:004001440.012
regulation of cellular ketone metabolic processGO:001056570.012
response to amphetamineGO:000197510.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
neuron projection extensionGO:1990138450.011
epidermal cell fate specificationGO:000995740.011
columnar cuboidal epithelial cell differentiationGO:0002065380.011
regulation of embryonic developmentGO:0045995470.011
actin cytoskeleton organizationGO:0030036630.011
organic cyclic compound metabolic processGO:19013603010.011
negative regulation of growthGO:0045926100.011
energy reserve metabolic processGO:000611220.011
gtp catabolic processGO:000618420.011
regulation of protein bindingGO:004339330.011
regulation of myelinationGO:003164110.011
cellular respirationGO:004533330.011
formation of anatomical boundaryGO:0048859140.011
antimicrobial humoral responseGO:001973020.011
circadian sleep wake cycleGO:004274520.011
protein modification processGO:00362111000.011
regulation of cytoplasmic transportGO:190364940.011
bmp signaling pathwayGO:0030509520.011
retinoic acid receptor signaling pathwayGO:0048384160.011
specification of axis polarityGO:006500140.011
calcium ion dependent exocytosisGO:001715610.011
regulation of purine nucleotide biosynthetic processGO:1900371150.011
stem cell differentiationGO:00488631170.011
cytoskeleton dependent cytokinesisGO:006164030.011
larval developmentGO:000216420.011
regulation of epithelial cell migrationGO:001063250.011
actin filament based processGO:0030029640.011
muscle system processGO:0003012200.011
cellular response to hypoxiaGO:007145610.011
heterocycle biosynthetic processGO:00181302150.011
aromatic compound biosynthetic processGO:00194382170.010
neuron projection developmentGO:00311751800.010
left right pattern formationGO:0060972190.010
regulation of cell motilityGO:2000145460.010
neural crest cell differentiationGO:0014033720.010
macromolecule methylationGO:0043414190.010
oocyte anterior posterior axis specificationGO:000731440.010
regulation of cell morphogenesis involved in differentiationGO:0010769380.010
regulation of transcription involved in cell fate commitmentGO:006085010.010
negative regulation of translationGO:001714810.010
response to bacteriumGO:0009617580.010
homeostasis of number of cells within a tissueGO:004887340.010
cyclic nucleotide biosynthetic processGO:0009190180.010
retinal rod cell developmentGO:004654840.010
organic substance biosynthetic processGO:19015762890.010
response to cortisolGO:005141410.010

slc6a8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.066
immune system diseaseDOID:291400.022
nervous system diseaseDOID:86300.017
eye and adnexa diseaseDOID:149200.017
retinal diseaseDOID:567900.017
eye diseaseDOID:561400.017
sensory system diseaseDOID:005015500.017
retinal degenerationDOID:846600.016
disease of metabolismDOID:001466700.015
Human
physical disorderDOID:008001500.012
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011
cancerDOID:16200.011
type 2 diabetes mellitusDOID:935200.010
carbohydrate metabolism diseaseDOID:005001300.010
diabetes mellitusDOID:935100.010
glucose metabolism diseaseDOID:419400.010
acquired metabolic diseaseDOID:006015800.010