Danio rerio

33 known processes

isca1

iron-sulfur cluster assembly 1

(Aliases: zgc:114185)

isca1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.088
agingGO:000756820.069
positive regulation of cell cycleGO:004578730.043
nitrogen compound metabolic processGO:00068073190.042
proteolysis involved in cellular protein catabolic processGO:005160330.040
protein localization to nucleusGO:003450430.040
multicellular organism growthGO:003526440.039
positive regulation of transportGO:005105020.039
positive regulation of catabolic processGO:000989640.039
establishment of protein localization to organelleGO:007259440.038
regulation of establishment of protein localizationGO:007020140.038
maintenance of locationGO:005123540.038
nucleocytoplasmic transportGO:000691340.037
nuclear transportGO:005116940.037
guanosine containing compound catabolic processGO:190106920.037
positive regulation of cellular catabolic processGO:003133130.037
protein import into nucleusGO:000660630.037
sensory organ developmentGO:00074233930.036
cellular protein catabolic processGO:004425740.036
heterocycle metabolic processGO:00464832900.036
regulation of protein transportGO:005122330.036
single organism nuclear importGO:190259330.036
cellular nitrogen compound metabolic processGO:00346412900.035
autophagyGO:000691440.035
negative regulation of protein phosphorylationGO:000193340.034
cellular amine metabolic processGO:004410620.034
amine metabolic processGO:000930820.033
protein targeting to nucleusGO:004474430.033
gtp metabolic processGO:004603940.033
cellular macromolecule metabolic processGO:00442603910.033
immune system processGO:00023762410.032
regulation of intracellular protein transportGO:003315730.032
cellular response to external stimulusGO:007149620.032
cellular aromatic compound metabolic processGO:00067252950.032
modification dependent protein catabolic processGO:001994130.031
nuclear importGO:005117030.031
regulation of cellular amino acid metabolic processGO:000652100.031
lipid storageGO:001991510.030
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.030
signal transductionGO:00071654550.030
protein importGO:001703830.030
guanosine containing compound metabolic processGO:190106840.030
regulation of biological qualityGO:00650082630.030
ubiquitin dependent protein catabolic processGO:000651130.030
modification dependent macromolecule catabolic processGO:004363230.030
morphogenesis of an epitheliumGO:00020093330.029
regulation of cytokine productionGO:000181730.029
regulation of protein localization to nucleusGO:190018020.029
regulation of cellular amine metabolic processGO:003323800.028
eye developmentGO:00016542770.028
regulation of protein targetingGO:190353320.028
positive regulation of cellular component biogenesisGO:004408930.028
cell surface receptor signaling pathwayGO:00071663250.028
mitochondrion organizationGO:000700540.027
organonitrogen compound metabolic processGO:1901564740.027
embryonic organ developmentGO:00485683810.027
gtp catabolic processGO:000618420.027
central nervous system developmentGO:00074173870.026
stem cell maintenanceGO:001982740.026
single organism metabolic processGO:00447102170.026
positive regulation of cellular amine metabolic processGO:003324000.026
proteasomal protein catabolic processGO:001049820.026
regulation of protein import into nucleusGO:004230620.026
regulation of multicellular organism growthGO:004001440.026
regulation of protein catabolic processGO:004217610.026
cellular response to nutrient levelsGO:003166920.026
negative regulation of biological processGO:00485193040.026
response to stressGO:00069502630.026
regulation of nucleocytoplasmic transportGO:004682220.025
regulation of cytoplasmic transportGO:190364940.025
response to drugGO:004249330.025
head developmentGO:00603223030.025
locomotionGO:00400113130.025
regulation of cellular ketone metabolic processGO:001056570.025
response to chemicalGO:00422213200.024
positive regulation of cellular amino acid metabolic processGO:004576400.024
gene expressionGO:00104672520.024
regulation of metabolic processGO:00192223590.024
negative regulation of protein kinase activityGO:000646940.024
meiotic nuclear divisionGO:000712640.024
small molecule metabolic processGO:0044281770.024
cellular ketone metabolic processGO:0042180110.024
phagocytosisGO:000690930.024
regulation of neural precursor cell proliferationGO:200017730.023
cellular response to extracellular stimulusGO:003166820.023
nucleobase containing compound metabolic processGO:00061392740.023
regulation of macromolecule metabolic processGO:00602553170.023
regulation of purine nucleotide catabolic processGO:003312120.023
regulation of nucleotide catabolic processGO:003081120.023
centrosome organizationGO:005129710.023
positive regulation of purine nucleotide catabolic processGO:003312310.023
regulation of bindingGO:005109830.022
single fertilizationGO:000733830.022
female gonad developmentGO:000858540.022
aromatic compound biosynthetic processGO:00194382170.022
regulation of developmental processGO:00507932470.022
cellular component movementGO:00069283350.022
neuron differentiationGO:00301823530.022
response to uvGO:000941130.022
organic cyclic compound metabolic processGO:19013603010.022
cellular response to lipopolysaccharideGO:007122230.022
regulation of cell shapeGO:000836010.022
regulation of synapse organizationGO:005080730.022
brain developmentGO:00074202930.021
determination of bilateral symmetryGO:00098552040.021
cognitionGO:005089010.021
rna localizationGO:000640340.021
tube morphogenesisGO:00352393490.021
cellular amino acid metabolic processGO:000652070.021
regulation of reproductive processGO:200024140.021
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.021
cellular response to starvationGO:000926710.021
oxoacid metabolic processGO:0043436310.021
regulation of primary metabolic processGO:00800903110.021
extrinsic apoptotic signaling pathwayGO:009719130.021
somatic muscle developmentGO:000752540.021
negative regulation of kinase activityGO:003367340.020
regulation of gtp catabolic processGO:003312420.020
peptide transportGO:001583310.020
muscle structure developmentGO:00610611960.020
negative regulation of catabolic processGO:000989530.020
symbiosis encompassing mutualism through parasitismGO:004440340.020
synaptic growth at neuromuscular junctionGO:005112420.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
positive regulation of secretionGO:005104710.020
nucleic acid metabolic processGO:00903042440.020
regulation of autophagyGO:001050630.020
meiotic cell cycle processGO:190304630.020
cytokinesisGO:000091030.020
adult behaviorGO:003053420.020
single organism organelle organizationGO:19025891990.020
peptidyl lysine acetylationGO:001839420.020
regulation of synapse assemblyGO:005196330.020
response to carbohydrateGO:000974330.020
digestive system developmentGO:00551232890.020
determination of left right symmetryGO:00073681790.020
organic acid metabolic processGO:0006082310.020
chordate embryonic developmentGO:00430092710.020
organelle organizationGO:00069962270.019
stem cell proliferationGO:007208940.019
protein metabolic processGO:00195381830.019
hemopoiesisGO:00300971830.019
regulation of reactive oxygen species metabolic processGO:200037720.019
response to external stimulusGO:00096052640.019
macromolecule biosynthetic processGO:00090592270.019
response to hexoseGO:000974630.019
positive regulation of nucleoside metabolic processGO:004597910.019
cellular component disassemblyGO:002241110.019
regulation of signal transductionGO:00099662250.019
heart developmentGO:00075073130.019
organic substance biosynthetic processGO:19015762890.019
immune system developmentGO:00025201910.019
negative regulation of cellular processGO:00485232830.019
carboxylic acid metabolic processGO:0019752220.019
single organism transportGO:00447652060.019
organic cyclic compound biosynthetic processGO:19013622230.019
cell part morphogenesisGO:00329902460.019
cellular component biogenesisGO:00440851780.018
cellular nitrogen compound biosynthetic processGO:00442712180.018
atp catabolic processGO:000620040.018
regulation of nitrogen compound metabolic processGO:00511712510.018
regionalizationGO:00030022740.018
heterocycle biosynthetic processGO:00181302150.018
localization of cellGO:00516742440.018
response to glucoseGO:000974930.018
regulation of cell activationGO:005086510.018
cell projection morphogenesisGO:00488582440.018
interspecies interaction between organismsGO:004441940.018
positive regulation of cytokine productionGO:000181920.018
regulation of response to stimulusGO:00485832690.018
endosomal transportGO:001619720.018
i kappab kinase nf kappab signalingGO:000724940.018
regulation of signalingGO:00230512350.018
post embryonic organ developmentGO:004856940.018
cellular macromolecule biosynthetic processGO:00346452240.018
negative regulation of cellular catabolic processGO:003133030.018
cellular response to biotic stimulusGO:007121630.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
camera type eye developmentGO:00430102220.018
rna metabolic processGO:00160702190.018
post embryonic morphogenesisGO:000988640.018
ribonucleoside monophosphate catabolic processGO:000915840.018
somitogenesisGO:0001756870.018
regulation of multicellular organismal developmentGO:20000262230.018
regulation of nucleoside metabolic processGO:000911820.018
single organism localizationGO:19025782250.018
single organism membrane fusionGO:004480120.018
internal protein amino acid acetylationGO:000647520.018
positive regulation of nucleotide catabolic processGO:003081310.018
generation of neuronsGO:00486993850.018
positive regulation of secretion by cellGO:190353210.017
biosynthetic processGO:00090582940.017
cell projection organizationGO:00300302840.017
response to monosaccharideGO:003428430.017
transportGO:00068102200.017
specification of symmetryGO:00097992040.017
regulation of protein complex assemblyGO:004325430.017
regulation of epithelial cell proliferationGO:005067830.017
vasculature developmentGO:00019442780.017
hematopoietic or lymphoid organ developmentGO:00485341910.017
blood vessel developmentGO:00015682460.017
zymogen activationGO:003163830.017
negative regulation of protein transportGO:005122430.017
secondary metabolic processGO:001974830.017
hormone transportGO:000991420.017
cell substrate adhesionGO:003158940.017
protein secretionGO:000930610.017
regulation of hormone secretionGO:004688320.017
adherens junction organizationGO:003433240.017
regulation of cellular protein catabolic processGO:190336210.017
digestive tract morphogenesisGO:00485462310.017
embryonic organ morphogenesisGO:00485622740.017
microtubule organizing center organizationGO:003102310.017
antimicrobial humoral responseGO:001973020.017
negative regulation of protein localization to nucleusGO:190018120.017
cellular component assemblyGO:00226071700.017
cellular component morphogenesisGO:00329893360.017
cell morphogenesisGO:00009022890.016
tissue remodelingGO:004877140.016
protein acetylationGO:000647320.016
lipid catabolic processGO:001604240.016
compound eye developmentGO:004874920.016
positive regulation of gtpase activityGO:004354710.016
regulation of protein ubiquitinationGO:003139630.016
establishment of localizationGO:00512342440.016
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.016
cellular protein metabolic processGO:00442671290.016
somatic stem cell maintenanceGO:003501910.016
multicellular organismal metabolic processGO:004423620.016
leukocyte proliferationGO:007066110.016
regulation of blood pressureGO:000821710.016
hormone secretionGO:004687920.016
response to corticosteroidGO:003196010.016
internal peptidyl lysine acetylationGO:001839320.016
regulation of cell communicationGO:00106462320.016
synaptic transmission cholinergicGO:000727140.016
b cell activationGO:004211320.016
nucleoside monophosphate catabolic processGO:000912540.016
carbohydrate homeostasisGO:003350010.016
multi organism cellular processGO:004476420.016
response to nutrientGO:000758430.016
purine ribonucleoside monophosphate catabolic processGO:000916940.016
regulation of synaptic plasticityGO:004816710.016
regulation of gtpase activityGO:004308720.016
membrane invaginationGO:001032410.016
regulation of multicellular organismal processGO:00512392770.016
development of primary female sexual characteristicsGO:004654540.016
fertilizationGO:000956630.016
exocytosisGO:000688710.015
nucleobase containing compound biosynthetic processGO:00346542050.015
positive regulation of biological processGO:00485182530.015
protein localization to plasma membraneGO:007265910.015
glucose homeostasisGO:004259310.015
negative regulation of cytoplasmic transportGO:190365020.015
cellular biosynthetic processGO:00442492860.015
protein acylationGO:004354330.015
amino acid transportGO:000686520.015
retina development in camera type eyeGO:00600411460.015
positive regulation of dna metabolic processGO:005105410.015
germ line stem cell maintenanceGO:003071820.015
positive regulation of gtp catabolic processGO:003312610.015
mononuclear cell proliferationGO:003294310.015
positive regulation of cell divisionGO:005178120.015
transcription dna templatedGO:00063511810.015
regulation of cellular metabolic processGO:00313233200.015
purine nucleoside monophosphate catabolic processGO:000912840.015
positive regulation of map kinase activityGO:004340630.015
female sex differentiationGO:004666040.015
regulation of metal ion transportGO:001095940.015
embryo development ending in birth or egg hatchingGO:00097922710.015
peptidyl serine modificationGO:001820920.015
mitotic dna integrity checkpointGO:004477440.015
system processGO:00030081850.014
production of molecular mediator of immune responseGO:000244020.014
developmental programmed cell deathGO:001062340.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
gland developmentGO:00487321430.014
lymphocyte proliferationGO:004665110.014
primary neural tube formationGO:001402010.014
cellular response to chemical stimulusGO:00708871570.014
negative regulation of nucleocytoplasmic transportGO:004682320.014
negative regulation of intracellular transportGO:003238730.014
blood vessel morphogenesisGO:00485142160.014
regulation of biosynthetic processGO:00098892500.014
positive regulation of immune effector processGO:000269930.014
cell motilityGO:00488702440.014
regulation of gene expressionGO:00104682650.014
negative regulation of mapk cascadeGO:004340940.014
protein complex disassemblyGO:004324110.014
regulation of organ growthGO:004662030.014
organelle fusionGO:004828430.014
protein polymerizationGO:005125840.014
sensory organ morphogenesisGO:00905962000.014
regulation of endothelial cell proliferationGO:000193610.014
regulation of meiotic cell cycleGO:005144510.014
tube closureGO:006060610.014
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.014
negative regulation of cytokine productionGO:000181810.014
positive regulation of stress activated mapk cascadeGO:003287430.014
digestive tract developmentGO:00485652650.014
regulation of protein bindingGO:004339330.014
nucleic acid templated transcriptionGO:00976591810.014
stem cell divisionGO:001714510.014
positive regulation of epithelial cell differentiationGO:003085820.014
cellular carbohydrate metabolic processGO:004426240.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
gastrulationGO:00073692080.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
centrosome cycleGO:000709810.013
regulation of production of molecular mediator of immune responseGO:000270010.013
positive regulation of canonical wnt signaling pathwayGO:009026340.013
macromolecule modificationGO:00434121110.013
positive regulation of epithelial cell proliferationGO:005067910.013
regulation of response to biotic stimulusGO:000283120.013
regulation of mrna processingGO:005068430.013
regulation of rho protein signal transductionGO:003502320.013
cell migrationGO:00164772370.013
cellular response to oxygen levelsGO:007145310.013
positive regulation of cytoskeleton organizationGO:005149530.013
macroautophagyGO:001623610.013
membrane fusionGO:006102520.013
transcription from rna polymerase ii promoterGO:0006366800.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
regulation of stem cell differentiationGO:200073640.013
regulation of transcription dna templatedGO:00063552130.013
phagocytosis engulfmentGO:000691110.013
golgi vesicle transportGO:004819330.013
positive regulation of protein complex assemblyGO:003133420.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
lateral line system developmentGO:0048925760.013
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.013
nucleic acid transportGO:005065720.013
regulation of organelle assemblyGO:190211540.013
homeostatic processGO:00425921420.013
positive regulation of translationGO:004572710.013
neuron developmentGO:00486662620.013
response to alkaloidGO:004327920.013
positive regulation of jnk cascadeGO:004633030.013
protein dephosphorylationGO:000647030.013
myeloid cell differentiationGO:0030099860.013
sensory perception of chemical stimulusGO:000760630.013
anterior posterior pattern specificationGO:00099521520.013
liver developmentGO:0001889960.013
skeletal system developmentGO:00015011810.013
muscle cell developmentGO:00550011150.013
regulation of dendrite developmentGO:005077330.013
regulation of rna metabolic processGO:00512522240.013
angiogenesisGO:00015251580.013
macromolecular complex disassemblyGO:003298410.013
negative regulation of map kinase activityGO:004340720.013
cell deathGO:00082191210.012
hepaticobiliary system developmentGO:0061008980.012
protein modification processGO:00362111000.012
cilium morphogenesisGO:0060271850.012
negative regulation of epithelial cell proliferationGO:005068010.012
positive regulation of cellular processGO:00485222010.012
striated muscle cell differentiationGO:00511461290.012
intracellular signal transductionGO:0035556850.012
convergent extensionGO:00600261180.012
phosphorus metabolic processGO:00067931090.012
eye morphogenesisGO:00485921440.012
positive regulation of epithelial cell migrationGO:001063420.012
negative regulation of secretionGO:005104820.012
cellular localizationGO:0051641970.012
somite developmentGO:0061053960.012
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.012
negative regulation of protein import into nucleusGO:004230820.012
pigmentationGO:0043473850.012
rna biosynthetic processGO:00327741810.012
apoptotic process involved in developmentGO:190274220.012
response to glucocorticoidGO:005138410.012
lateral inhibitionGO:004633110.012
positive regulation of chromosome organizationGO:200125210.012
striated muscle cell developmentGO:00550021080.012
nuclear exportGO:005116810.012
regulation of jak stat cascadeGO:004642530.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
determination of heart left right asymmetryGO:00613711170.012
dorsal ventral pattern formationGO:00099531250.012
cell matrix adhesionGO:000716040.012
cellular response to molecule of bacterial originGO:007121930.012
response to organic substanceGO:00100331530.012
heart morphogenesisGO:00030071560.012
regulation of cellular biosynthetic processGO:00313262450.012
cellular response to radiationGO:007147840.012
spermatid developmentGO:000728620.012
developmental growthGO:00485891660.012
spermatid differentiationGO:004851520.012
ventricular cardiac muscle tissue developmentGO:000322930.012
regulation of rna biosynthetic processGO:20011412130.012
g1 s transition of mitotic cell cycleGO:000008210.012
cilium assemblyGO:0042384580.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
locomotor rhythmGO:004547530.012
inositol lipid mediated signalingGO:004801720.012
astrocyte differentiationGO:004870810.012
regulation of tube sizeGO:003515020.012
protein homooligomerizationGO:005126030.012
ameboidal type cell migrationGO:00016671430.012
ovulation cycle processGO:002260220.012
regulation of blood vessel sizeGO:005088020.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
epithelial tube morphogenesisGO:00605621480.012
negative regulation of intracellular protein transportGO:009031730.012
cellular response to organic substanceGO:00713101050.012
regulation of macromolecule biosynthetic processGO:00105562250.012
regulation of cell differentiationGO:00455951420.012
protein complex localizationGO:003150310.012
erk1 and erk2 cascadeGO:007037140.011
mesenchyme developmentGO:00604851270.011
positive regulation of striated muscle cell differentiationGO:005115510.011
neurotransmitter transportGO:000683620.011
negative regulation of secretion by cellGO:190353120.011
rna transportGO:005065820.011
protein polyubiquitinationGO:000020940.011
positive regulation of neuron deathGO:190121610.011
sensory system developmentGO:0048880760.011
ventricular cardiac muscle tissue morphogenesisGO:005501020.011
growthGO:00400071740.011
mitotic dna damage checkpointGO:004477340.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
cell cycle g1 s phase transitionGO:004484310.011
programmed cell deathGO:00125011190.011
response to xenobiotic stimulusGO:0009410450.011
regulation of cell substrate adhesionGO:001081010.011
cilium organizationGO:0044782710.011
ovulation cycleGO:004269820.011
regulation of inflammatory responseGO:005072720.011
b cell mediated immunityGO:001972430.011
negative regulation of dna metabolic processGO:005105340.011
regulation of dna replicationGO:000627530.011
establishment of protein localization to plasma membraneGO:009000210.011
regulation of stem cell proliferationGO:007209120.011
b cell differentiationGO:003018310.011
peptidyl threonine phosphorylationGO:001810710.011
actin filament polymerizationGO:003004120.011
regulation of neurotransmitter transportGO:005158810.011
cytoskeleton organizationGO:0007010960.011
positive regulation of cell activationGO:005086710.011
negative regulation of chromosome organizationGO:200125110.011
apoptotic processGO:00069151160.011
chemosensory behaviorGO:000763510.011
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.011
cell cycle arrestGO:000705010.011
cytoplasm organizationGO:000702840.011
response to other organismGO:0051707970.011
regulation of cell deathGO:00109411030.011
positive regulation of cell adhesionGO:004578510.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
positive regulation of myeloid cell differentiationGO:004563920.011
startle responseGO:000196440.011
viral processGO:001603210.011
cytoskeleton dependent cytokinesisGO:006164030.011
phosphate containing compound metabolic processGO:00067961080.011
cellular component assembly involved in morphogenesisGO:00109271070.011
regulation of calcium ion transportGO:005192420.011
reactive nitrogen species metabolic processGO:200105700.011
monocyte differentiationGO:003022420.011
phosphatidylinositol mediated signalingGO:004801520.011
regulation of neurotransmitter secretionGO:004692810.011
cellular response to hypoxiaGO:007145610.011
negative regulation of multi organism processGO:004390130.011
ear developmentGO:00435831270.010
response to biotic stimulusGO:0009607970.010
positive regulation of metabolic processGO:00098931080.010
toll like receptor signaling pathwayGO:000222440.010
establishment of rna localizationGO:005123630.010
mitochondrial transportGO:000683920.010
lateral line developmentGO:0048882660.010
response to amino acidGO:004320020.010
regulation of cell projection assemblyGO:006049140.010
cellular protein modification processGO:00064641000.010
segmentationGO:0035282970.010
regulation of transporter activityGO:003240920.010
positive regulation of lymphocyte mediated immunityGO:000270810.010
neuroblast proliferationGO:000740520.010
regulation of circadian rhythmGO:004275240.010
rna 3 end processingGO:003112320.010

isca1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.041
immune system diseaseDOID:291400.020
musculoskeletal system diseaseDOID:1700.019
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
organ system cancerDOID:005068600.016
nervous system diseaseDOID:86300.014
disease of metabolismDOID:001466700.014
cardiovascular system diseaseDOID:128700.013
connective tissue diseaseDOID:6500.011
bone marrow diseaseDOID:496100.011
hematopoietic system diseaseDOID:7400.011
myopathyDOID:42300.011
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011
sensory system diseaseDOID:005015500.010