Danio rerio

0 known processes

spice1

spindle and centriole associated protein 1

(Aliases: ccdc52,zgc:101558)

spice1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.096
agingGO:000756820.059
maintenance of locationGO:005123540.042
positive regulation of transportGO:005105020.042
multicellular organism growthGO:003526440.038
establishment of protein localization to organelleGO:007259440.037
regulation of multicellular organism growthGO:004001440.036
phagocytosisGO:000690930.036
nucleocytoplasmic transportGO:000691340.036
mitochondrion organizationGO:000700540.034
nuclear transportGO:005116940.034
amine metabolic processGO:000930820.033
nitrogen compound metabolic processGO:00068073190.033
proteolysis involved in cellular protein catabolic processGO:005160330.033
protein localization to nucleusGO:003450430.033
negative regulation of protein phosphorylationGO:000193340.031
lipid storageGO:001991510.031
positive regulation of cellular component biogenesisGO:004408930.031
cellular macromolecule metabolic processGO:00442603910.030
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.030
cellular protein catabolic processGO:004425740.030
meiotic nuclear divisionGO:000712640.030
ubiquitin dependent protein catabolic processGO:000651130.030
cellular response to external stimulusGO:007149620.030
signal transductionGO:00071654550.030
cellular nitrogen compound metabolic processGO:00346412900.029
modification dependent protein catabolic processGO:001994130.029
regulation of cytokine productionGO:000181730.029
protein import into nucleusGO:000660630.029
protein targeting to nucleusGO:004474430.029
positive regulation of catabolic processGO:000989640.028
cellular amine metabolic processGO:004410620.028
modification dependent macromolecule catabolic processGO:004363230.028
single organism nuclear importGO:190259330.028
regulation of establishment of protein localizationGO:007020140.028
organic cyclic compound metabolic processGO:19013603010.028
protein importGO:001703830.028
cell substrate adhesionGO:003158940.027
proteasomal protein catabolic processGO:001049820.027
positive regulation of cellular catabolic processGO:003133130.027
regulation of cellular amine metabolic processGO:003323800.027
regulation of protein transportGO:005122330.026
guanosine containing compound catabolic processGO:190106920.026
positive regulation of cell cycleGO:004578730.026
regulation of macromolecule metabolic processGO:00602553170.026
regulation of protein targetingGO:190353320.026
regulation of meiotic cell cycleGO:005144510.025
nuclear importGO:005117030.025
heterocycle metabolic processGO:00464832900.025
gtp metabolic processGO:004603940.025
guanosine containing compound metabolic processGO:190106840.025
cellular response to extracellular stimulusGO:003166820.025
cellular ketone metabolic processGO:0042180110.025
gtp catabolic processGO:000618420.025
cellular aromatic compound metabolic processGO:00067252950.024
gene expressionGO:00104672520.024
stem cell maintenanceGO:001982740.024
rna localizationGO:000640340.024
regulation of cytoplasmic transportGO:190364940.024
regulation of cellular amino acid metabolic processGO:000652100.024
organic acid catabolic processGO:001605430.024
regulation of protein localization to nucleusGO:190018020.024
regulation of mrna processingGO:005068430.024
nucleobase containing compound metabolic processGO:00061392740.024
organic substance biosynthetic processGO:19015762890.024
autophagyGO:000691440.024
single organism metabolic processGO:00447102170.023
response to chemicalGO:00422213200.023
small molecule metabolic processGO:0044281770.023
cognitionGO:005089010.023
cellular response to nutrient levelsGO:003166920.023
regulation of nucleocytoplasmic transportGO:004682220.023
atp catabolic processGO:000620040.023
biosynthetic processGO:00090582940.023
regulation of intracellular protein transportGO:003315730.023
regulation of synapse organizationGO:005080730.023
regulation of protein import into nucleusGO:004230620.023
protein acetylationGO:000647320.022
ribonucleoside monophosphate catabolic processGO:000915840.022
regulation of metal ion transportGO:001095940.022
regulation of nucleoside metabolic processGO:000911820.022
regulation of cellular ketone metabolic processGO:001056570.022
meiotic cell cycle processGO:190304630.022
regulation of protein catabolic processGO:004217610.022
oxoacid metabolic processGO:0043436310.022
cellular amino acid metabolic processGO:000652070.022
organic acid metabolic processGO:0006082310.022
regulation of cellular metabolic processGO:00313233200.022
regulation of bindingGO:005109830.022
regulation of cell activationGO:005086510.021
rna metabolic processGO:00160702190.021
morphogenesis of an epitheliumGO:00020093330.021
negative regulation of protein kinase activityGO:000646940.021
negative regulation of biological processGO:00485193040.021
negative regulation of kinase activityGO:003367340.021
female sex differentiationGO:004666040.021
cell surface receptor signaling pathwayGO:00071663250.021
extrinsic apoptotic signaling pathwayGO:009719130.021
regulation of nucleotide catabolic processGO:003081120.021
regulation of cell shapeGO:000836010.021
regulation of reproductive processGO:200024140.021
organelle fusionGO:004828430.021
cytokinesisGO:000091030.021
single organism membrane fusionGO:004480120.020
sensory organ developmentGO:00074233930.020
tube morphogenesisGO:00352393490.020
synaptic growth at neuromuscular junctionGO:005112420.020
cellular biosynthetic processGO:00442492860.020
nucleoside monophosphate catabolic processGO:000912540.020
organonitrogen compound metabolic processGO:1901564740.020
immune system processGO:00023762410.020
regulation of protein complex assemblyGO:004325430.020
regulation of purine nucleotide catabolic processGO:003312120.020
stem cell proliferationGO:007208940.020
regulation of primary metabolic processGO:00800903110.020
membrane fusionGO:006102520.020
regulation of synapse assemblyGO:005196330.020
central nervous system developmentGO:00074173870.020
peptidyl lysine acetylationGO:001839420.020
aromatic compound biosynthetic processGO:00194382170.020
cellular response to starvationGO:000926710.020
carboxylic acid metabolic processGO:0019752220.020
purine nucleoside monophosphate catabolic processGO:000912840.020
regulation of mrna splicing via spliceosomeGO:004802430.020
regulation of metabolic processGO:00192223590.019
locomotionGO:00400113130.019
nucleic acid metabolic processGO:00903042440.019
negative regulation of cellular processGO:00485232830.019
heterocycle biosynthetic processGO:00181302150.019
regulation of nitrogen compound metabolic processGO:00511712510.019
response to drugGO:004249330.019
golgi vesicle transportGO:004819330.019
spermatid developmentGO:000728620.019
cellular component movementGO:00069283350.019
regulation of gtp catabolic processGO:003312420.019
response to carbohydrateGO:000974330.019
protein localization to plasma membraneGO:007265910.019
regulation of response to stimulusGO:00485832690.019
regulation of protein modification by small protein conjugation or removalGO:190332030.019
organic cyclic compound biosynthetic processGO:19013622230.019
microtubule organizing center organizationGO:003102310.019
protein metabolic processGO:00195381830.019
digestive system developmentGO:00551232890.018
leukocyte proliferationGO:007066110.018
response to uvGO:000941130.018
carboxylic acid catabolic processGO:004639530.018
macromolecule biosynthetic processGO:00090592270.018
internal protein amino acid acetylationGO:000647520.018
regulation of neural precursor cell proliferationGO:200017730.018
cell projection organizationGO:00300302840.018
cellular component disassemblyGO:002241110.018
regulation of biosynthetic processGO:00098892500.018
lipid catabolic processGO:001604240.018
cellular macromolecule biosynthetic processGO:00346452240.018
spermatid differentiationGO:004851520.018
cell cycle g1 s phase transitionGO:004484310.018
purine ribonucleoside monophosphate catabolic processGO:000916940.018
cellular nitrogen compound biosynthetic processGO:00442712180.018
positive regulation of purine nucleotide catabolic processGO:003312310.018
regulation of signal transductionGO:00099662250.018
cell migrationGO:00164772370.018
response to monosaccharideGO:003428430.018
negative regulation of catabolic processGO:000989530.018
transcription dna templatedGO:00063511810.018
adult behaviorGO:003053420.017
single organism localizationGO:19025782250.017
locomotor rhythmGO:004547530.017
positive regulation of cellular amine metabolic processGO:003324000.017
positive regulation of nucleoside metabolic processGO:004597910.017
establishment of localizationGO:00512342440.017
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
positive regulation of cytokine productionGO:000181920.017
internal peptidyl lysine acetylationGO:001839320.017
positive regulation of immune effector processGO:000269930.017
positive regulation of protein complex assemblyGO:003133420.017
negative regulation of cytoplasmic transportGO:190365020.017
regulation of synaptic growth at neuromuscular junctionGO:000858210.017
positive regulation of dna metabolic processGO:005105410.017
regulation of alternative mrna splicing via spliceosomeGO:000038110.017
cell projection morphogenesisGO:00488582440.017
transportGO:00068102200.017
cellular carbohydrate metabolic processGO:004426240.017
phagocytosis engulfmentGO:000691110.017
positive regulation of secretionGO:005104710.017
neuron differentiationGO:00301823530.017
eye developmentGO:00016542770.017
heart developmentGO:00075073130.017
response to stressGO:00069502630.017
i kappab kinase nf kappab signalingGO:000724940.017
nucleobase containing compound biosynthetic processGO:00346542050.017
post embryonic organ developmentGO:004856940.017
cellular component morphogenesisGO:00329893360.017
regulation of nucleobase containing compound metabolic processGO:00192192500.017
regionalizationGO:00030022740.016
regulation of autophagyGO:001050630.016
camera type eye developmentGO:00430102220.016
protein acylationGO:004354330.016
head developmentGO:00603223030.016
g1 s transition of mitotic cell cycleGO:000008210.016
digestive tract developmentGO:00485652650.016
erk1 and erk2 cascadeGO:007037140.016
fertilizationGO:000956630.016
cell matrix adhesionGO:000716040.016
adherens junction organizationGO:003433240.016
regulation of gtpase activityGO:004308720.016
regulation of protein ubiquitinationGO:003139630.016
cell part morphogenesisGO:00329902460.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
endosomal transportGO:001619720.016
regulation of stem cell proliferationGO:007209120.016
positive regulation of gtp catabolic processGO:003312610.016
protein complex disassemblyGO:004324110.016
exocytosisGO:000688710.016
regulation of gene expressionGO:00104682650.016
positive regulation of nucleotide catabolic processGO:003081310.016
regulation of signalingGO:00230512350.016
cellular response to oxygen levelsGO:007145310.016
cell morphogenesisGO:00009022890.016
convergent extensionGO:00600261180.016
regulation of cellular biosynthetic processGO:00313262450.016
nuclear exportGO:005116810.016
macromolecular complex disassemblyGO:003298410.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
regulation of erk1 and erk2 cascadeGO:007037240.016
positive regulation of cell activationGO:005086710.016
positive regulation of gtpase activityGO:004354710.016
regulation of inflammatory responseGO:005072720.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
regulation of rna metabolic processGO:00512522240.016
embryonic organ developmentGO:00485683810.016
mitotic dna integrity checkpointGO:004477440.016
mononuclear cell proliferationGO:003294310.016
negative regulation of sequestering of calcium ionGO:005128340.016
membrane invaginationGO:001032410.015
generation of neuronsGO:00486993850.015
positive regulation of secretion by cellGO:190353210.015
neuroblast proliferationGO:000740520.015
localization of cellGO:00516742440.015
regulation of biological qualityGO:00650082630.015
secondary metabolic processGO:001974830.015
small molecule catabolic processGO:004428230.015
compound eye developmentGO:004874920.015
lateral inhibitionGO:004633110.015
rna biosynthetic processGO:00327741810.015
negative regulation of cellular catabolic processGO:003133030.015
response to glucoseGO:000974930.015
regulation of rna biosynthetic processGO:20011412130.015
regulation of cellular protein catabolic processGO:190336210.015
regulation of organ growthGO:004662030.015
specification of symmetryGO:00097992040.015
regulation of macromolecule biosynthetic processGO:00105562250.015
cytoskeleton dependent cytokinesisGO:006164030.015
meiotic chromosome segregationGO:004513230.015
nucleic acid transportGO:005065720.015
response to external stimulusGO:00096052640.015
protein polymerizationGO:005125840.015
developmental programmed cell deathGO:001062340.015
regulation of cell communicationGO:00106462320.015
negative regulation of intracellular protein transportGO:009031730.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.015
tissue remodelingGO:004877140.015
organelle organizationGO:00069962270.015
cell motilityGO:00488702440.015
gastrulationGO:00073692080.015
response to hexoseGO:000974630.015
interspecies interaction between organismsGO:004441940.015
positive regulation of biological processGO:00485182530.015
regulation of multicellular organismal processGO:00512392770.015
single organism transportGO:00447652060.015
positive regulation of erk1 and erk2 cascadeGO:007037420.015
lymphocyte proliferationGO:004665110.015
regulation of developmental processGO:00507932470.015
negative regulation of intracellular transportGO:003238730.014
chordate embryonic developmentGO:00430092710.014
cellular component assemblyGO:00226071700.014
response to nutrientGO:000758430.014
primary neural tube formationGO:001402010.014
sleepGO:003043110.014
peptidyl serine modificationGO:001820920.014
vasculature developmentGO:00019442780.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
single fertilizationGO:000733830.014
cilium morphogenesisGO:0060271850.014
peptide transportGO:001583310.014
regulation of stem cell differentiationGO:200073640.014
sequestering of metal ionGO:005123830.014
negative regulation of mapk cascadeGO:004340940.014
digestive tract morphogenesisGO:00485462310.014
regulation of blood pressureGO:000821710.014
regulation of sequestering of calcium ionGO:005128240.014
macroautophagyGO:001623610.014
positive regulation of cytoskeleton organizationGO:005149530.014
growthGO:00400071740.014
negative regulation of cytokine productionGO:000181810.014
neurotransmitter transportGO:000683620.014
mitotic dna damage checkpointGO:004477340.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
cellular amide metabolic processGO:004360340.014
signal transduction in absence of ligandGO:003803410.014
viral processGO:001603210.014
positive regulation of translationGO:004572710.014
intracellular mrna localizationGO:000829810.013
centrosome duplicationGO:005129810.013
cellular response to radiationGO:007147840.013
development of primary female sexual characteristicsGO:004654540.013
cellular component biogenesisGO:00440851780.013
cellular response to chemical stimulusGO:00708871570.013
single organism organelle organizationGO:19025891990.013
regulation of jak stat cascadeGO:004642530.013
negative regulation of protein transportGO:005122430.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
regulation of transcription dna templatedGO:00063552130.013
production of molecular mediator of immune responseGO:000244020.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
cytoplasm organizationGO:000702840.013
germ line stem cell maintenanceGO:003071820.013
nucleobase containing compound transportGO:001593120.013
b cell activationGO:004211320.013
regulation of circadian rhythmGO:004275240.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
stem cell divisionGO:001714510.013
glucose homeostasisGO:004259310.013
establishment of protein localization to plasma membraneGO:009000210.013
positive regulation of i kappab kinase nf kappab signalingGO:004312330.013
translational initiationGO:000641330.013
regulation of transporter activityGO:003240920.013
multi organism cellular processGO:004476420.013
developmental growthGO:00485891660.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
brain developmentGO:00074202930.013
monocarboxylic acid catabolic processGO:007232930.013
protein homooligomerizationGO:005126030.013
carbohydrate homeostasisGO:003350010.013
positive regulation of map kinase activityGO:004340630.013
protein stabilizationGO:005082120.013
alcohol biosynthetic processGO:004616520.013
positive regulation of cell adhesionGO:004578510.013
tube closureGO:006060610.013
somatic muscle developmentGO:000752540.013
inositol lipid mediated signalingGO:004801720.013
blood vessel developmentGO:00015682460.013
multi organism processGO:00517041340.013
rna transportGO:005065820.013
regulation of neurotransmitter transportGO:005158810.013
cell cycle arrestGO:000705010.013
neuron developmentGO:00486662620.013
apoptotic process involved in developmentGO:190274220.013
hematopoietic or lymphoid organ developmentGO:00485341910.012
cellular lipid catabolic processGO:004424230.012
release of sequestered calcium ion into cytosolGO:005120930.012
blood vessel morphogenesisGO:00485142160.012
somatic stem cell maintenanceGO:003501910.012
cellular protein metabolic processGO:00442671290.012
negative regulation of nuclear divisionGO:005178430.012
regulation of epithelial cell proliferationGO:005067830.012
nucleic acid templated transcriptionGO:00976591810.012
cellular response to decreased oxygen levelsGO:003629410.012
protein dephosphorylationGO:000647030.012
positive regulation of chromatin modificationGO:190331010.012
response to organic substanceGO:00100331530.012
regulation of cell substrate adhesionGO:001081010.012
cellular response to hypoxiaGO:007145610.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
embryonic organ morphogenesisGO:00485622740.012
regulation of calcium ion transportGO:005192420.012
chemosensory behaviorGO:000763510.012
protein secretionGO:000930610.012
homeostatic processGO:00425921420.012
peptidyl serine phosphorylationGO:001810510.012
lipid oxidationGO:003444010.012
centrosome cycleGO:000709810.012
rna modificationGO:000945120.012
hemopoiesisGO:00300971830.012
angiogenesisGO:00015251580.012
intracellular signal transductionGO:0035556850.012
sequestering of calcium ionGO:005120830.012
establishment of rna localizationGO:005123630.012
cytosolic calcium ion transportGO:006040130.012
ovulation cycleGO:004269820.012
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.012
determination of left right symmetryGO:00073681790.012
toll like receptor signaling pathwayGO:000222440.012
alternative mrna splicing via spliceosomeGO:000038010.012
negative regulation of protein localization to nucleusGO:190018120.012
regulation of production of molecular mediator of immune responseGO:000270010.012
embryo development ending in birth or egg hatchingGO:00097922710.012
rna 3 end processingGO:003112320.012
response to topologically incorrect proteinGO:003596620.012
regulation of response to biotic stimulusGO:000283120.012
negative regulation of protein import into nucleusGO:004230820.012
negative regulation of macromolecule metabolic processGO:0010605760.012
mitochondrial transportGO:000683920.012
neuromuscular synaptic transmissionGO:000727420.012
female gonad developmentGO:000858540.012
peptidyl threonine phosphorylationGO:001810710.012
regulation of chromosome segregationGO:005198310.012
transcription from rna polymerase ii promoterGO:0006366800.012
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
macromolecule modificationGO:00434121110.012
dorsal ventral pattern formationGO:00099531250.012
negative regulation of defense responseGO:003134820.012
positive regulation of chromosome organizationGO:200125210.012
cellular response to light stimulusGO:007148240.011
cellular response to biotic stimulusGO:007121630.011
hormone transportGO:000991420.011
regulation of synaptic plasticityGO:004816710.011
female meiotic divisionGO:000714320.011
regulation of dna replicationGO:000627530.011
negative regulation of map kinase activityGO:004340720.011
immune system developmentGO:00025201910.011
actin filament polymerizationGO:003004120.011
er to golgi vesicle mediated transportGO:000688810.011
positive regulation of epithelial cell proliferationGO:005067910.011
sensory organ morphogenesisGO:00905962000.011
fatty acid catabolic processGO:000906210.011
phosphatidylinositol mediated signalingGO:004801520.011
positive regulation of cellular processGO:00485222010.011
response to corticosteroidGO:003196010.011
regulation of dendrite developmentGO:005077330.011
regulation of neurotransmitter secretionGO:004692810.011
somite developmentGO:0061053960.011
hormone secretionGO:004687920.011
calcium ion transport into cytosolGO:006040230.011
negative regulation of reproductive processGO:200024230.011
synaptic vesicle localizationGO:009747910.011
system processGO:00030081850.011
positive regulation of epithelial cell migrationGO:001063420.011
regulation of protein bindingGO:004339330.011
mitotic cytokinesisGO:000028130.011
neuron neuron synaptic transmissionGO:000727010.011
g2 dna damage checkpointGO:003157230.011
neurotransmitter secretionGO:000726920.011
regulation of reactive oxygen species metabolic processGO:200037720.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
regulation of protein complex disassemblyGO:004324410.011
antimicrobial humoral responseGO:001973020.011
actin polymerization or depolymerizationGO:000815420.011
cell agingGO:000756920.011
protein heterooligomerizationGO:005129110.011
positive regulation of stress activated mapk cascadeGO:003287430.011
cell substrate junction assemblyGO:000704420.011
regulation of blood vessel sizeGO:005088020.011
negative regulation of metabolic processGO:0009892860.011
double strand break repairGO:000630230.011
cellular respirationGO:004533330.011
cell deathGO:00082191210.011
establishment of synaptic vesicle localizationGO:009748010.011
enzyme linked receptor protein signaling pathwayGO:00071671060.010
protein modification processGO:00362111000.010
deathGO:00162651210.010
muscle structure developmentGO:00610611960.010
vacuolar transportGO:000703420.010
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.010
positive regulation of cell divisionGO:005178120.010
response to hydrogen peroxideGO:004254230.010
ameboidal type cell migrationGO:00016671430.010
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.010
negative regulation of rna splicingGO:003311910.010
synaptic vesicle transportGO:004848910.010
retina development in camera type eyeGO:00600411460.010
regulation of carbohydrate metabolic processGO:000610940.010
negative regulation of multi organism processGO:004390130.010
cellular response to molecule of bacterial originGO:007121930.010
anterior posterior pattern specificationGO:00099521520.010
lipid homeostasisGO:005508830.010
regulation of multicellular organismal developmentGO:20000262230.010
protein polyubiquitinationGO:000020940.010
regulation of response to extracellular stimulusGO:003210410.010
cellular transition metal ion homeostasisGO:004691630.010
organelle assemblyGO:00709251100.010
cilium organizationGO:0044782710.010
startle responseGO:000196440.010
double strand break repair via homologous recombinationGO:000072410.010
axon developmentGO:00615641660.010
determination of bilateral symmetryGO:00098552040.010
response to abiotic stimulusGO:00096281220.010

spice1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
nervous system diseaseDOID:86300.021
musculoskeletal system diseaseDOID:1700.019
cancerDOID:16200.015
organ system cancerDOID:005068600.015
disease of cellular proliferationDOID:1456600.015
disease of metabolismDOID:001466700.015
muscular diseaseDOID:008000000.014
muscle tissue diseaseDOID:6600.014
immune system diseaseDOID:291400.012
myopathyDOID:42300.011
sensory system diseaseDOID:005015500.011
inherited metabolic disorderDOID:65500.011