Danio rerio

0 known processes

gins2

GINS complex subunit 2

(Aliases: si:dkey-265o13.3,zgc:112262)

gins2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
double strand break repair via homologous recombinationGO:000072410.766
recombinational repairGO:000072510.611
histone phosphorylationGO:001657220.458
double strand break repairGO:000630230.316
regulation of dna recombinationGO:000001820.307
meiotic nuclear divisionGO:000712640.233
mitotic dna integrity checkpointGO:004477440.230
organelle organizationGO:00069962270.166
response to alkaloidGO:004327920.151
cellular response to radiationGO:007147840.149
regulation of meiotic cell cycleGO:005144510.145
nucleobase containing compound metabolic processGO:00061392740.145
protein acylationGO:004354330.144
cellular macromolecule metabolic processGO:00442603910.144
cellular nitrogen compound metabolic processGO:00346412900.136
chromosome organizationGO:0051276310.132
organic cyclic compound metabolic processGO:19013603010.132
response to drugGO:004249330.124
meiotic cell cycle processGO:190304630.123
nitrogen compound metabolic processGO:00068073190.115
histone h3 k4 methylationGO:005156820.112
response to stressGO:00069502630.111
intra s dna damage checkpointGO:003157310.096
organic substance biosynthetic processGO:19015762890.091
cellular biosynthetic processGO:00442492860.090
regulation of dna replicationGO:000627530.090
cell cycle g2 m phase transitionGO:004483940.087
protein acetylationGO:000647320.084
signal transduction by p53 class mediatorGO:0072331130.082
regulation of cellular amine metabolic processGO:003323800.082
positive regulation of histone modificationGO:003105810.077
sister chromatid cohesionGO:000706220.075
meiosis iGO:000712710.070
negative regulation of cellular processGO:00485232830.069
positive regulation of chromatin modificationGO:190331010.068
regulation of protein import into nucleusGO:004230620.065
amine metabolic processGO:000930820.064
mitotic dna damage checkpointGO:004477340.064
protein metabolic processGO:00195381830.063
cellular response to external stimulusGO:007149620.061
macromolecule biosynthetic processGO:00090592270.060
heterocycle metabolic processGO:00464832900.060
peptidyl lysine acetylationGO:001839420.058
chromosome organization involved in meiosisGO:007019210.056
positive regulation of catabolic processGO:000989640.056
establishment of protein localization to organelleGO:007259440.055
meiotic chromosome segregationGO:004513230.053
specification of axis polarityGO:006500140.053
positive regulation of cellular catabolic processGO:003133130.051
cellular amino acid metabolic processGO:000652070.051
regulation of cellular amino acid metabolic processGO:000652100.051
negative regulation of protein localization to nucleusGO:190018120.051
response to organic substanceGO:00100331530.049
modification dependent protein catabolic processGO:001994130.048
single organism nuclear importGO:190259330.048
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233290.046
cellular aromatic compound metabolic processGO:00067252950.046
cellular response to light stimulusGO:007148240.044
single organism organelle organizationGO:19025891990.044
negative regulation of cytoplasmic transportGO:190365020.044
small molecule metabolic processGO:0044281770.043
negative regulation of mitosisGO:004583930.043
cellular ketone metabolic processGO:0042180110.042
protein targeting to nucleusGO:004474430.042
purine nucleoside monophosphate catabolic processGO:000912840.042
macromolecular complex subunit organizationGO:0043933740.042
peptidyl serine phosphorylationGO:001810510.041
internal peptidyl lysine acetylationGO:001839320.041
regulation of establishment of protein localizationGO:007020140.041
dna metabolic processGO:0006259270.041
protein modification processGO:00362111000.041
cellular protein catabolic processGO:004425740.039
response to chemicalGO:00422213200.039
cellular amine metabolic processGO:004410620.039
regulation of protein targetingGO:190353320.038
negative regulation of dna metabolic processGO:005105340.038
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.038
histone modificationGO:0016570200.037
organic acid metabolic processGO:0006082310.037
negative regulation of cell cycle g2 m phase transitionGO:190275010.037
regulation of dna templated transcription in response to stressGO:004362000.036
cellular protein modification processGO:00064641000.036
organonitrogen compound metabolic processGO:1901564740.035
negative regulation of chromosome organizationGO:200125110.035
protein importGO:001703830.034
regulation of nitrogen compound metabolic processGO:00511712510.034
nucleic acid metabolic processGO:00903042440.034
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.034
regulation of protein ubiquitinationGO:003139630.033
agingGO:000756820.033
oxoacid metabolic processGO:0043436310.033
dna recombinationGO:000631050.033
macromolecule modificationGO:00434121110.033
cellular macromolecule biosynthetic processGO:00346452240.032
ribonucleoside monophosphate catabolic processGO:000915840.032
carboxylic acid metabolic processGO:0019752220.032
embryo development ending in birth or egg hatchingGO:00097922710.032
Worm
mitotic g2 dna damage checkpointGO:000709530.032
cell cycle g1 s phase transitionGO:004484310.031
regulation of cellular ketone metabolic processGO:001056570.031
maintenance of locationGO:005123540.031
negative regulation of protein transportGO:005122430.031
g2 m transition of mitotic cell cycleGO:000008640.031
organism emergence from protective structureGO:007168440.030
macromolecular complex disassemblyGO:003298410.030
chromatin organizationGO:0006325220.030
rna metabolic processGO:00160702190.029
hatchingGO:003518840.029
female meiotic divisionGO:000714320.029
positive regulation of dna metabolic processGO:005105410.029
macromolecule methylationGO:0043414190.029
regulation of protein modification by small protein conjugation or removalGO:190332030.029
protein import into nucleusGO:000660630.028
negative regulation of protein import into nucleusGO:004230820.028
multicellular organism growthGO:003526440.028
histone lysine methylationGO:0034968120.028
peptidyl serine modificationGO:001820920.027
regulation of protein catabolic processGO:004217610.027
gene expressionGO:00104672520.026
positive regulation of chromosome organizationGO:200125210.026
regulation of cell cycleGO:0051726520.026
i kappab kinase nf kappab signalingGO:000724940.026
centrosome organizationGO:005129710.026
negative regulation of intracellular transportGO:003238730.025
g1 s transition of mitotic cell cycleGO:000008210.025
reciprocal dna recombinationGO:003582510.025
single organism metabolic processGO:00447102170.025
deoxyribose phosphate metabolic processGO:001969210.025
spindle assemblyGO:005122520.025
cell cycleGO:0007049930.025
phosphorus metabolic processGO:00067931090.025
cellular response to dna damage stimulusGO:0006974240.024
methylationGO:0032259220.024
organic cyclic compound biosynthetic processGO:19013622230.024
nuclear transportGO:005116940.024
cellular protein metabolic processGO:00442671290.024
cellular component biogenesisGO:00440851780.024
g2 dna damage checkpointGO:003157230.024
negative regulation of cell cycleGO:0045786140.024
negative regulation of response to dna damage stimulusGO:200102130.023
nuclear importGO:005117030.023
regulation of macromolecule biosynthetic processGO:00105562250.023
cognitionGO:005089010.023
regulation of response to stimulusGO:00485832690.023
biosynthetic processGO:00090582940.023
response to uvGO:000941130.022
microtubule organizing center organizationGO:003102310.022
response to inorganic substanceGO:0010035380.022
protein methylationGO:0006479130.022
synapsisGO:000712910.022
sex determinationGO:000753010.022
dorsal ventral pattern formationGO:00099531250.022
regulation of metabolic processGO:00192223590.022
regulation of histone methylationGO:003106030.021
regulation of dna metabolic processGO:0051052110.021
positive regulation of cellular processGO:00485222010.021
telomere maintenanceGO:000072310.021
establishment of localizationGO:00512342440.021
Worm
protein localization to nucleusGO:003450430.021
organic substance catabolic processGO:1901575280.020
nucleoside monophosphate catabolic processGO:000912540.020
covalent chromatin modificationGO:0016569200.020
dna repairGO:000628160.020
proteolysis involved in cellular protein catabolic processGO:005160330.020
proteasomal protein catabolic processGO:001049820.019
lipid storageGO:001991510.019
negative regulation of nucleocytoplasmic transportGO:004682320.019
regulation of nucleocytoplasmic transportGO:004682220.019
single organism reproductive processGO:0044702400.019
Worm
sensory organ developmentGO:00074233930.019
regulation of chromosome segregationGO:005198310.018
intracellular signal transductionGO:0035556850.018
negative regulation of i kappab kinase nf kappab signalingGO:004312410.018
response to amino acidGO:004320020.018
aromatic compound biosynthetic processGO:00194382170.018
programmed cell deathGO:00125011190.018
cellular response to stressGO:0033554620.018
dna damage checkpointGO:000007760.018
regulation of macromolecule metabolic processGO:00602553170.018
positive regulation of macromolecule metabolic processGO:0010604930.018
oocyte maturationGO:000155640.018
larval developmentGO:000216420.018
Worm
dna catabolic processGO:000630810.018
response to organic cyclic compoundGO:0014070510.018
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.017
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.017
specification of symmetryGO:00097992040.017
organelle fissionGO:0048285230.017
nuclear divisionGO:0000280230.017
phosphate containing compound metabolic processGO:00067961080.017
cellular response to organic substanceGO:00713101050.017
gtp catabolic processGO:000618420.017
chemosensory behaviorGO:000763510.017
cellular response to endogenous stimulusGO:0071495680.016
regulation of mitotic cell cycleGO:0007346250.016
positive regulation of cell cycleGO:004578730.016
modification dependent macromolecule catabolic processGO:004363230.016
regulation of cellular metabolic processGO:00313233200.016
organ regenerationGO:003110010.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.016
positive regulation of biological processGO:00485182530.016
regulation of biological qualityGO:00650082630.016
regulation of response to stressGO:0080134360.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
lipid catabolic processGO:001604240.016
ubiquitin dependent protein catabolic processGO:000651130.016
centrosome cycleGO:000709810.015
cellular response to organic cyclic compoundGO:0071407380.015
response to nitrogen compoundGO:1901698190.015
negative regulation of mapk cascadeGO:004340940.015
determination of left right symmetryGO:00073681790.015
regulation of protein localization to nucleusGO:190018020.015
atp catabolic processGO:000620040.015
organelle assemblyGO:00709251100.015
immunoglobulin mediated immune responseGO:001606430.015
chromosome segregationGO:0007059120.015
regulation of multicellular organism growthGO:004001440.015
nucleocytoplasmic transportGO:000691340.015
negative regulation of cell divisionGO:005178240.014
lipid homeostasisGO:005508830.014
cellular macromolecule catabolic processGO:0044265120.014
regulation of biosynthetic processGO:00098892500.014
rna localizationGO:000640340.014
cytoskeleton organizationGO:0007010960.014
cellular response to oxygen levelsGO:007145310.014
dna biosynthetic processGO:007189730.014
regulation of bindingGO:005109830.014
cell morphogenesisGO:00009022890.014
regulation of transcription dna templatedGO:00063552130.014
mitotic g2 m transition checkpointGO:004481830.014
blood vessel morphogenesisGO:00485142160.014
pyrimidine containing compound metabolic processGO:007252730.013
protein complex biogenesisGO:0070271300.013
negative regulation of protein phosphorylationGO:000193340.013
adult behaviorGO:003053420.013
cell cycle arrestGO:000705010.013
mitotic cell cycle processGO:1903047480.013
regulation of nucleobase containing compound metabolic processGO:00192192500.013
apoptotic processGO:00069151160.013
response to abiotic stimulusGO:00096281220.013
carbohydrate derivative biosynthetic processGO:1901137430.013
regulation of rna metabolic processGO:00512522240.013
carbohydrate derivative metabolic processGO:1901135610.013
intracellular mrna localizationGO:000829810.013
negative regulation of intracellular protein transportGO:009031730.013
response to metal ionGO:0010038340.013
regulation of programmed cell deathGO:00430671010.013
transcription dna templatedGO:00063511810.013
transcription from rna polymerase ii promoterGO:0006366800.013
regulation of cysteine type endopeptidase activityGO:2000116210.012
regulation of cellular protein metabolic processGO:0032268520.012
cellular response to chemical stimulusGO:00708871570.012
positive regulation of cellular amine metabolic processGO:003324000.012
meiotic cell cycleGO:005132150.012
regulation of stem cell proliferationGO:007209120.012
response to light stimulusGO:0009416460.012
macromolecule catabolic processGO:0009057150.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
immune system processGO:00023762410.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
production of molecular mediator of immune responseGO:000244020.012
reciprocal meiotic recombinationGO:000713110.012
b cell activationGO:004211320.012
regulation of mitotic cell cycle phase transitionGO:190199080.012
chromatin modificationGO:0016568210.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
regulation of cytoplasmic transportGO:190364940.012
cellular nitrogen compound biosynthetic processGO:00442712180.011
nucleobase containing small molecule metabolic processGO:0055086320.011
regulation of cellular component organizationGO:0051128860.011
positive regulation of metabolic processGO:00098931080.011
regulation of mitochondrion organizationGO:001082110.011
pyrimidine containing compound biosynthetic processGO:007252820.011
response to glucoseGO:000974930.011
energy reserve metabolic processGO:000611220.011
response to monosaccharideGO:003428430.011
protein alkylationGO:0008213130.011
developmental programmed cell deathGO:001062340.011
determination of bilateral symmetryGO:00098552040.011
positive regulation of gene expressionGO:0010628710.011
development of primary female sexual characteristicsGO:004654540.011
negative regulation of biological processGO:00485193040.011
regulation of apoptotic processGO:0042981980.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
cellular localizationGO:0051641970.011
mitotic cell cycle checkpointGO:000709350.011
cellular lipid catabolic processGO:004424230.010
regulation of cell deathGO:00109411030.010
zymogen activationGO:003163830.010
regulation of cell cycle g2 m phase transitionGO:190274940.010
positive regulation of nitrogen compound metabolic processGO:0051173690.010
secondary metabolic processGO:001974830.010
mitotic cell cycle embryonicGO:004544820.010
cellular component assemblyGO:00226071700.010
cellular response to extracellular stimulusGO:003166820.010
regulation of peptidase activityGO:0052547230.010

gins2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.032
cancerDOID:16200.032
thoracic cancerDOID:509300.028
organ system cancerDOID:005068600.028
disease of metabolismDOID:001466700.026
inherited metabolic disorderDOID:65500.026
disease of anatomical entityDOID:700.018
immune system diseaseDOID:291400.013