Danio rerio

0 known processes

LOC559147

novel protein similar to vertebrate hairy and enhancer of split 2 (Drosophila) (HES2)

LOC559147 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.113
signal transductionGO:00071654550.108
larval developmentGO:000216420.103
tube morphogenesisGO:00352393490.084
lipid catabolic processGO:001604240.058
maintenance of locationGO:005123540.057
g protein coupled receptor signaling pathwayGO:0007186740.056
cell surface receptor signaling pathwayGO:00071663250.054
response to external stimulusGO:00096052640.053
lipid storageGO:001991510.052
embryonic organ developmentGO:00485683810.051
stem cell maintenanceGO:001982740.048
morphogenesis of an epitheliumGO:00020093330.046
phagocytosisGO:000690930.044
aromatic compound biosynthetic processGO:00194382170.041
nitrogen compound metabolic processGO:00068073190.040
chordate embryonic developmentGO:00430092710.039
transportGO:00068102200.039
brain developmentGO:00074202930.038
heart developmentGO:00075073130.038
biosynthetic processGO:00090582940.038
sensory organ developmentGO:00074233930.037
digestive tract morphogenesisGO:00485462310.037
regulation of signal transductionGO:00099662250.036
specification of symmetryGO:00097992040.036
determination of bilateral symmetryGO:00098552040.036
heterocycle metabolic processGO:00464832900.036
muscle structure developmentGO:00610611960.036
negative regulation of protein phosphorylationGO:000193340.036
head developmentGO:00603223030.035
response to drugGO:004249330.035
central nervous system developmentGO:00074173870.035
eye developmentGO:00016542770.035
amine metabolic processGO:000930820.035
regulation of establishment of protein localizationGO:007020140.035
cellular nitrogen compound metabolic processGO:00346412900.034
digestive system developmentGO:00551232890.034
cellular amine metabolic processGO:004410620.034
small molecule metabolic processGO:0044281770.034
rna metabolic processGO:00160702190.034
cellular macromolecule metabolic processGO:00442603910.033
determination of left right symmetryGO:00073681790.033
system processGO:00030081850.033
adult behaviorGO:003053420.032
regulation of signalingGO:00230512350.032
regionalizationGO:00030022740.031
regulation of neural precursor cell proliferationGO:200017730.031
nuclear transportGO:005116940.030
cellular response to external stimulusGO:007149620.030
vasculature developmentGO:00019442780.030
regulation of protein transportGO:005122330.030
regulation of multicellular organism growthGO:004001440.030
regulation of metal ion transportGO:001095940.030
carboxylic acid metabolic processGO:0019752220.030
protein importGO:001703830.029
regulation of inflammatory responseGO:005072720.029
establishment of protein localization to organelleGO:007259440.029
nucleocytoplasmic transportGO:000691340.029
organic substance biosynthetic processGO:19015762890.029
regulation of macromolecule metabolic processGO:00602553170.029
regulation of cellular metabolic processGO:00313233200.029
nuclear importGO:005117030.029
digestive tract developmentGO:00485652650.029
protein targeting to nucleusGO:004474430.029
response to vitaminGO:003327330.029
protein localization to nucleusGO:003450430.029
gastrulationGO:00073692080.028
organonitrogen compound metabolic processGO:1901564740.028
oxoacid metabolic processGO:0043436310.028
response to nutrientGO:000758430.028
cellular ketone metabolic processGO:0042180110.028
response to chemicalGO:00422213200.028
sensory organ morphogenesisGO:00905962000.028
regulation of cellular amine metabolic processGO:003323800.028
embryonic organ morphogenesisGO:00485622740.028
cellular biosynthetic processGO:00442492860.028
organic acid metabolic processGO:0006082310.027
stem cell proliferationGO:007208940.027
response to stressGO:00069502630.027
urea transportGO:0015840110.027
regulation of biological qualityGO:00650082630.027
muscle cell differentiationGO:00426921390.027
generation of neuronsGO:00486993850.027
regulation of protein catabolic processGO:004217610.027
regulation of cellular ketone metabolic processGO:001056570.027
heart loopingGO:0001947940.026
negative regulation of protein kinase activityGO:000646940.026
single organism metabolic processGO:00447102170.026
response to monosaccharideGO:003428430.026
single organism transportGO:00447652060.026
regulation of cytokine productionGO:000181730.026
positive regulation of catabolic processGO:000989640.026
locomotionGO:00400113130.026
establishment of localizationGO:00512342440.026
positive regulation of transportGO:005105020.026
female sex differentiationGO:004666040.026
cellular nitrogen compound biosynthetic processGO:00442712180.025
regulation of cellular amino acid metabolic processGO:000652100.025
positive regulation of cell cycleGO:004578730.025
mitochondrion organizationGO:000700540.025
regulation of tube sizeGO:003515020.025
neuron differentiationGO:00301823530.025
nucleobase containing compound metabolic processGO:00061392740.025
regulation of developmental processGO:00507932470.025
single organism nuclear importGO:190259330.024
protein import into nucleusGO:000660630.024
multicellular organism growthGO:003526440.024
cognitionGO:005089010.024
sensory perception of chemical stimulusGO:000760630.024
regulation of nitrogen compound metabolic processGO:00511712510.024
response to carbohydrateGO:000974330.023
regulation of cell communicationGO:00106462320.023
single organism localizationGO:19025782250.023
determination of heart left right asymmetryGO:00613711170.023
single organism biosynthetic processGO:0044711710.023
negative regulation of cellular processGO:00485232830.023
somitogenesisGO:0001756870.023
regulation of metabolic processGO:00192223590.023
cellular aromatic compound metabolic processGO:00067252950.023
nucleobase containing compound biosynthetic processGO:00346542050.023
negative regulation of protein transportGO:005122430.023
negative regulation of kinase activityGO:003367340.022
regulation of blood vessel sizeGO:005088020.022
regulation of protein complex assemblyGO:004325430.022
regulation of intracellular protein transportGO:003315730.022
somite developmentGO:0061053960.022
regulation of cytoplasmic transportGO:190364940.022
positive regulation of cellular catabolic processGO:003133130.022
macromolecule biosynthetic processGO:00090592270.022
regulation of protein localization to nucleusGO:190018020.022
epithelial tube morphogenesisGO:00605621480.022
cellular macromolecule biosynthetic processGO:00346452240.021
regulation of protein targetingGO:190353320.021
regulation of cell activationGO:005086510.021
hindbrain developmentGO:0030902910.021
heart morphogenesisGO:00030071560.021
cellular component morphogenesisGO:00329893360.021
response to bacteriumGO:0009617580.021
cellular amino acid metabolic processGO:000652070.021
regulation of protein import into nucleusGO:004230620.021
blood vessel developmentGO:00015682460.021
regulation of multicellular organismal processGO:00512392770.021
lipid homeostasisGO:005508830.021
cellular carbohydrate metabolic processGO:004426240.021
carbohydrate homeostasisGO:003350010.021
response to hexoseGO:000974630.021
response to corticosteroidGO:003196010.020
guanosine containing compound metabolic processGO:190106840.020
neurological system processGO:0050877620.020
regulation of nucleocytoplasmic transportGO:004682220.020
response to biotic stimulusGO:0009607970.020
stem cell divisionGO:001714510.020
muscle cell developmentGO:00550011150.020
regulation of blood pressureGO:000821710.020
cellular response to nutrient levelsGO:003166920.020
modification dependent macromolecule catabolic processGO:004363230.020
gtp catabolic processGO:000618420.020
development of primary female sexual characteristicsGO:004654540.020
positive regulation of inflammatory responseGO:005072910.020
heterocycle biosynthetic processGO:00181302150.020
fluid transportGO:0042044170.020
regulation of reactive oxygen species metabolic processGO:200037720.020
negative regulation of biological processGO:00485193040.019
regulation of macromolecule biosynthetic processGO:00105562250.019
chemosensory behaviorGO:000763510.019
xenobiotic metabolic processGO:000680540.019
response to uvGO:000941130.019
regulation of primary metabolic processGO:00800903110.019
camera type eye developmentGO:00430102220.019
guanosine containing compound catabolic processGO:190106920.019
response to endogenous stimulusGO:0009719830.019
cellular aldehyde metabolic processGO:000608140.019
multi organism processGO:00517041340.019
cellular response to extracellular stimulusGO:003166820.019
nucleic acid metabolic processGO:00903042440.018
organic cyclic compound metabolic processGO:19013603010.018
meiotic cell cycle processGO:190304630.018
striated muscle cell differentiationGO:00511461290.018
response to glucoseGO:000974930.018
triglyceride homeostasisGO:007032820.018
cellular response to biotic stimulusGO:007121630.018
regulation of gene expressionGO:00104682650.018
embryonic heart tube developmentGO:00350501330.018
embryonic heart tube morphogenesisGO:00031431080.018
polyol transportGO:001579170.018
protein metabolic processGO:00195381830.018
cellular response to chemical stimulusGO:00708871570.018
regulation of synaptic plasticityGO:004816710.018
gene expressionGO:00104672520.018
regulation of response to stimulusGO:00485832690.018
protein acetylationGO:000647320.018
positive regulation of cytokine productionGO:000181920.018
nucleic acid templated transcriptionGO:00976591810.017
cellular component biogenesisGO:00440851780.017
embryo development ending in birth or egg hatchingGO:00097922710.017
gtp metabolic processGO:004603940.017
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.017
organelle organizationGO:00069962270.017
cell morphogenesisGO:00009022890.017
positive regulation of biological processGO:00485182530.017
cellular component assembly involved in morphogenesisGO:00109271070.017
response to hormoneGO:0009725480.017
regulation of sodium ion transportGO:000202820.017
modification dependent protein catabolic processGO:001994130.017
neurotransmitter secretionGO:000726920.017
regulation of reproductive processGO:200024140.017
regulation of rna biosynthetic processGO:20011412130.017
angiogenesisGO:00015251580.017
ubiquitin dependent protein catabolic processGO:000651130.017
female gonad developmentGO:000858540.017
regulation of stem cell proliferationGO:007209120.017
regulation of bindingGO:005109830.017
positive regulation of secretion by cellGO:190353210.017
compound eye developmentGO:004874920.017
autophagyGO:000691440.017
long chain fatty acid transportGO:001590910.017
regulation of biosynthetic processGO:00098892500.016
positive regulation of dna metabolic processGO:005105410.016
regulation of cellular biosynthetic processGO:00313262450.016
synaptic growth at neuromuscular junctionGO:005112420.016
regulation of rna metabolic processGO:00512522240.016
phosphate containing compound metabolic processGO:00067961080.016
negative regulation of secretion by cellGO:190353120.016
negative regulation of nucleocytoplasmic transportGO:004682320.016
negative regulation of catabolic processGO:000989530.016
cellular response to starvationGO:000926710.016
phagocytosis engulfmentGO:000691110.016
gland developmentGO:00487321430.016
anterior posterior pattern specificationGO:00099521520.016
regulation of ion transmembrane transporter activityGO:003241220.016
cell motilityGO:00488702440.016
transcription from rna polymerase ii promoterGO:0006366800.016
regulation of dna replicationGO:000627530.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
hemopoiesisGO:00300971830.015
homeostatic processGO:00425921420.015
nucleoside phosphate biosynthetic processGO:1901293210.015
localization of cellGO:00516742440.015
glucose homeostasisGO:004259310.015
negative regulation of protein complex assemblyGO:003133310.015
cell projection morphogenesisGO:00488582440.015
regulation of nucleoside metabolic processGO:000911820.015
germ line stem cell maintenanceGO:003071820.015
positive regulation of cellular amine metabolic processGO:003324000.015
urogenital system developmentGO:0001655970.015
rna biosynthetic processGO:00327741810.015
negative regulation of mapk cascadeGO:004340940.015
segmentationGO:0035282970.015
response to external biotic stimulusGO:0043207970.015
ion transportGO:00068111140.015
regulation of organ growthGO:004662030.015
neuron neuron synaptic transmissionGO:000727010.015
proteolysis involved in cellular protein catabolic processGO:005160330.015
response to organic substanceGO:00100331530.015
meiotic nuclear divisionGO:000712640.015
response to other organismGO:0051707970.015
b cell activationGO:004211320.015
peptidyl lysine acetylationGO:001839420.015
negative regulation of intracellular transportGO:003238730.015
ovulation cycleGO:004269820.015
peptide transportGO:001583310.015
cellular response to lipopolysaccharideGO:007122230.015
energy reserve metabolic processGO:000611220.015
response to glucocorticoidGO:005138410.014
regulation of carbohydrate metabolic processGO:000610940.014
glycerol transportGO:001579370.014
morphogenesis of an epithelial sheetGO:0002011490.014
regulation of transporter activityGO:003240920.014
negative regulation of cytoplasmic transportGO:190365020.014
protein secretionGO:000930610.014
regulation of circadian rhythmGO:004275240.014
protein homooligomerizationGO:005126030.014
endocrine processGO:005088620.014
response to metal ionGO:0010038340.014
lateral line system developmentGO:0048925760.014
transcription dna templatedGO:00063511810.014
sensory system developmentGO:0048880760.014
protein acylationGO:004354330.014
cellular component movementGO:00069283350.014
positive regulation of cellular component biogenesisGO:004408930.014
internal peptidyl lysine acetylationGO:001839320.014
water homeostasisGO:003010440.014
positive regulation of blood circulationGO:190352420.014
regulation of purine nucleotide catabolic processGO:003312120.014
regulation of nucleotide catabolic processGO:003081120.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
growthGO:00400071740.014
cellular response to radiationGO:007147840.014
spermatid developmentGO:000728620.014
immune system developmentGO:00025201910.014
positive regulation of secretionGO:005104710.014
neuroblast proliferationGO:000740520.014
retina development in camera type eyeGO:00600411460.014
cellular protein catabolic processGO:004425740.014
cellular response to hormone stimulusGO:0032870390.014
dorsal ventral pattern formationGO:00099531250.014
regulation of localizationGO:00328791040.013
regulation of nucleobase containing compound metabolic processGO:00192192500.013
blood vessel morphogenesisGO:00485142160.013
regulation of synapse organizationGO:005080730.013
single organism organelle organizationGO:19025891990.013
alcohol biosynthetic processGO:004616520.013
cellular response to endogenous stimulusGO:0071495680.013
nucleotide biosynthetic processGO:0009165210.013
regulation of anatomical structure morphogenesisGO:00226031300.013
regulation of cell differentiationGO:00455951420.013
negative regulation of dna metabolic processGO:005105340.013
negative regulation of defense responseGO:003134820.013
long chain fatty acid metabolic processGO:000167610.013
response to oxygen containing compoundGO:1901700550.013
lymphocyte proliferationGO:004665110.013
internal protein amino acid acetylationGO:000647520.013
organelle assemblyGO:00709251100.013
regulation of autophagyGO:001050630.013
negative regulation of neural precursor cell proliferationGO:200017810.013
developmental growthGO:00485891660.013
regulation of hormone secretionGO:004688320.013
regulation of transcription from rna polymerase ii promoterGO:00063571140.013
organic cyclic compound biosynthetic processGO:19013622230.013
cellular response to molecule of bacterial originGO:007121930.013
regulation of gtp catabolic processGO:003312420.013
cell part morphogenesisGO:00329902460.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
response to abiotic stimulusGO:00096281220.013
inositol lipid mediated signalingGO:004801720.013
intracellular signal transductionGO:0035556850.013
cellular protein modification processGO:00064641000.012
somatic muscle developmentGO:000752540.012
regulation of dendrite developmentGO:005077330.012
regulation of transcription dna templatedGO:00063552130.012
cellular component assemblyGO:00226071700.012
ear developmentGO:00435831270.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
cell projection organizationGO:00300302840.012
cellular response to organic substanceGO:00713101050.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
gas transportGO:001566930.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
regulation of nucleic acid templated transcriptionGO:19035062130.012
response to woundingGO:00096111160.012
regulation of epithelial cell proliferationGO:005067830.012
phosphorus metabolic processGO:00067931090.012
mononuclear cell proliferationGO:003294310.012
organophosphate biosynthetic processGO:0090407230.012
regulation of gtpase activityGO:004308720.012
negative regulation of secretionGO:005104820.012
cell migrationGO:00164772370.012
negative regulation of cell communicationGO:0010648960.012
renal system developmentGO:0072001940.012
intracellular receptor signaling pathwayGO:0030522300.012
response to acid chemicalGO:0001101170.012
cellular component disassemblyGO:002241110.012
leukocyte proliferationGO:007066110.012
positive regulation of cell activationGO:005086710.012
negative regulation of multicellular organismal processGO:0051241690.012
carbohydrate biosynthetic processGO:001605110.012
ovulation cycle processGO:002260220.012
interspecies interaction between organismsGO:004441940.012
negative regulation of response to stimulusGO:00485851040.012
hormone secretionGO:004687920.012
lateral line developmentGO:0048882660.012
cell morphogenesis involved in neuron differentiationGO:00486671630.012
neuronal action potentialGO:0019228180.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
negative regulation of protein localization to nucleusGO:190018120.012
protein modification processGO:00362111000.012
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.012
i kappab kinase nf kappab signalingGO:000724940.012
production of molecular mediator of immune responseGO:000244020.011
neuron developmentGO:00486662620.011
extrinsic apoptotic signaling pathwayGO:009719130.011
negative regulation of developmental processGO:0051093650.011
eye morphogenesisGO:00485921440.011
cyclic nucleotide metabolic processGO:0009187180.011
negative regulation of intracellular protein transportGO:009031730.011
negative regulation of reproductive processGO:200024230.011
immune system processGO:00023762410.011
g1 s transition of mitotic cell cycleGO:000008210.011
stem cell differentiationGO:00488631170.011
regulation of multicellular organismal developmentGO:20000262230.011
smooth muscle contractionGO:000693920.011
regulation of myotube differentiationGO:001083020.011
hepaticobiliary system developmentGO:0061008980.011
reactive oxygen species biosynthetic processGO:190340910.011
macromolecule localizationGO:0033036540.011
spermatid differentiationGO:004851520.011
water transportGO:0006833150.011
cellular response to reactive oxygen speciesGO:003461420.011
positive regulation of nucleotide catabolic processGO:003081310.011
neuromast developmentGO:0048884460.011
oocyte maturationGO:000155640.011
positive regulation of nucleoside metabolic processGO:004597910.011
ion transmembrane transportGO:0034220910.011
regulation of transmembrane transporter activityGO:002289820.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
protein stabilizationGO:005082120.011
small molecule catabolic processGO:004428230.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
kidney developmentGO:0001822920.011
regulation of synapse assemblyGO:005196330.011
blood circulationGO:0008015870.011
fatty acid transportGO:001590810.011
positive regulation of myeloid cell differentiationGO:004563920.011
camera type eye morphogenesisGO:00485931080.011
cyclic purine nucleotide metabolic processGO:0052652180.011
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.011
muscle organ developmentGO:00075171010.011
regulation of cellular protein catabolic processGO:190336210.011
organism emergence from protective structureGO:007168440.011
acylglycerol homeostasisGO:005509020.011
cell proliferationGO:0008283800.011
negative regulation of epithelial cell proliferationGO:005068010.011
negative regulation of signal transductionGO:0009968940.011
cell matrix adhesionGO:000716040.011
skeletal system developmentGO:00015011810.011
regulation of calcium ion transportGO:005192420.011
tissue remodelingGO:004877140.011
negative regulation of cellular catabolic processGO:003133030.011
regulation of meiotic cell cycleGO:005144510.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
hormone transportGO:000991420.010
regulation of lipid transportGO:003236840.010
complement activationGO:000695630.010
response to alkaloidGO:004327920.010
neurotransmitter transportGO:000683620.010
membrane invaginationGO:001032410.010
negative regulation of protein import into nucleusGO:004230820.010
neural retina developmentGO:0003407490.010
cell cycle g1 s phase transitionGO:004484310.010
nucleoside triphosphate biosynthetic processGO:000914220.010
regulation of protein ubiquitinationGO:003139630.010
regulation of protein modification by small protein conjugation or removalGO:190332030.010
response to unfolded proteinGO:000698620.010
regulation of programmed cell deathGO:00430671010.010
pancreas developmentGO:0031016840.010
regulation of i kappab kinase nf kappab signalingGO:004312240.010
cellular response to light stimulusGO:007148240.010
cell substrate adhesionGO:003158940.010
multicellular organismal metabolic processGO:004423620.010
purine ribonucleotide biosynthetic processGO:0009152200.010
macromolecule modificationGO:00434121110.010
macromolecular complex disassemblyGO:003298410.010
regulation of cell shapeGO:000836010.010
regulation of response to extracellular stimulusGO:003210410.010
inorganic anion transportGO:0015698250.010
rna localizationGO:000640340.010
lipid metabolic processGO:0006629520.010
regulation of dna recombinationGO:000001820.010

LOC559147 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
nervous system diseaseDOID:86300.020
eye and adnexa diseaseDOID:149200.016
sensory system diseaseDOID:005015500.016
eye diseaseDOID:561400.016
disease of cellular proliferationDOID:1456600.014
organ system cancerDOID:005068600.013
cancerDOID:16200.013
disease of metabolismDOID:001466700.013
musculoskeletal system diseaseDOID:1700.013
cardiovascular system diseaseDOID:128700.010