Danio rerio

82 known processes

lrrc50

leucine rich repeat containing 50

(Aliases: dnaaf1,zgc:56169)

lrrc50 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cilium movementGO:0003341260.976
Human
digestive tract developmentGO:00485652650.919
specification of symmetryGO:00097992040.907
cilium organizationGO:0044782710.890
embryonic organ developmentGO:00485683810.880
microtubule bundle formationGO:000157890.858
cilium assemblyGO:0042384580.855
cellular component biogenesisGO:00440851780.853
cilium morphogenesisGO:0060271850.837
determination of bilateral symmetryGO:00098552040.821
cell projection organizationGO:00300302840.758
embryonic heart tube morphogenesisGO:00031431080.741
organelle assemblyGO:00709251100.727
localization of cellGO:00516742440.694
determination of left right symmetryGO:00073681790.676
tube morphogenesisGO:00352393490.627
cellular component movementGO:00069283350.573
brain developmentGO:00074202930.567
epithelial cilium movement involved in determination of left right asymmetryGO:006028780.527
urogenital system developmentGO:0001655970.506
morphogenesis of an epitheliumGO:00020093330.482
heart loopingGO:0001947940.473
renal tubule morphogenesisGO:006133310.469
kidney developmentGO:0001822920.467
cell migrationGO:00164772370.445
nephron morphogenesisGO:007202820.416
determination of heart left right asymmetryGO:00613711170.399
digestive system developmentGO:00551232890.398
embryonic organ morphogenesisGO:00485622740.380
cell projection morphogenesisGO:00488582440.361
renal system developmentGO:0072001940.345
organelle organizationGO:00069962270.341
compound eye developmentGO:004874920.332
nephron epithelium morphogenesisGO:007208810.328
nephron tubule morphogenesisGO:007207810.328
cellular component assemblyGO:00226071700.325
pronephros developmentGO:0048793690.305
gastrulationGO:00073692080.305
cell projection assemblyGO:0030031640.299
cell morphogenesisGO:00009022890.286
hard palate developmentGO:006002240.286
digestive tract morphogenesisGO:00485462310.272
ear developmentGO:00435831270.272
positive regulation of rna biosynthetic processGO:1902680570.255
regulation of primary metabolic processGO:00800903110.252
heart developmentGO:00075073130.234
cell motilityGO:00488702440.234
cell part morphogenesisGO:00329902460.230
heart joggingGO:0003146400.223
epithelial cilium movementGO:0003351150.217
microtubule based movementGO:0007018330.206
Human
positive regulation of biological processGO:00485182530.199
positive regulation of nitrogen compound metabolic processGO:0051173690.196
regulation of macromolecule metabolic processGO:00602553170.196
dorsal ventral pattern formationGO:00099531250.196
axonemal dynein complex assemblyGO:007028650.180
Human
sensory system developmentGO:0048880760.178
positive regulation of blood circulationGO:190352420.177
locomotionGO:00400113130.172
larval developmentGO:000216420.164
motile cilium assemblyGO:004445840.163
Human
signal transductionGO:00071654550.156
chordate embryonic developmentGO:00430092710.155
multi organism reproductive processGO:0044703360.154
regulation of cellular macromolecule biosynthetic processGO:20001122220.151
central nervous system developmentGO:00074173870.151
aorta morphogenesisGO:003590930.146
neural tube developmentGO:0021915620.145
neuron developmentGO:00486662620.142
cellular component assembly involved in morphogenesisGO:00109271070.140
regulation of nitrogen compound metabolic processGO:00511712510.139
photoreceptor cell developmentGO:0042461400.137
microtubule based processGO:0007017600.136
neuron differentiationGO:00301823530.134
multi organism processGO:00517041340.131
protein metabolic processGO:00195381830.130
sensory organ morphogenesisGO:00905962000.124
eye photoreceptor cell differentiationGO:0001754450.120
heterocycle biosynthetic processGO:00181302150.119
organic cyclic compound biosynthetic processGO:19013622230.118
regulation of cellular metabolic processGO:00313233200.117
positive regulation of cellular processGO:00485222010.114
head developmentGO:00603223030.113
axoneme assemblyGO:003508290.112
regulation of blood pressureGO:000821710.111
inner ear developmentGO:00488391260.111
sensory organ developmentGO:00074233930.110
response to stressGO:00069502630.108
pronephric nephron developmentGO:0039019140.104
positive regulation of biosynthetic processGO:0009891680.104
positive regulation of gene expressionGO:0010628710.103
multicellular organism reproductionGO:0032504350.103
hemopoiesisGO:00300971830.100
rna metabolic processGO:00160702190.099
distal tubule developmentGO:007201710.097
regulation of anatomical structure morphogenesisGO:00226031300.097
macromolecule biosynthetic processGO:00090592270.096
inner ear receptor cell differentiationGO:0060113290.096
positive regulation of rna metabolic processGO:0051254590.095
macromolecular complex subunit organizationGO:0043933740.095
Human
muscle structure developmentGO:00610611960.094
developmental growthGO:00485891660.094
stem cell maintenanceGO:001982740.094
cellular nitrogen compound metabolic processGO:00346412900.093
nucleobase containing compound metabolic processGO:00061392740.093
nitrogen compound metabolic processGO:00068073190.093
embryo development ending in birth or egg hatchingGO:00097922710.092
convergent extensionGO:00600261180.091
biosynthetic processGO:00090582940.090
renal tubule developmentGO:006132650.085
cilium movement involved in cell motilityGO:006029430.085
positive regulation of catabolic processGO:000989640.083
reproductive processGO:0022414400.082
regulation of signal transductionGO:00099662250.079
positive regulation of cellular biosynthetic processGO:0031328680.078
regulation of nucleobase containing compound metabolic processGO:00192192500.077
cellular aromatic compound metabolic processGO:00067252950.076
mesenchyme developmentGO:00604851270.076
regulation of multicellular organismal developmentGO:20000262230.076
single organism localizationGO:19025782250.076
lateral line system developmentGO:0048925760.074
otic vesicle developmentGO:0071599420.071
response to drugGO:004249330.071
establishment of localizationGO:00512342440.070
regulation of localizationGO:00328791040.069
Human
spemann organizer formationGO:0060061100.069
response to chemicalGO:00422213200.068
cellular macromolecule biosynthetic processGO:00346452240.068
regulation of protein complex assemblyGO:004325430.067
eye morphogenesisGO:00485921440.066
kidney morphogenesisGO:0060993150.066
neurological system processGO:0050877620.065
sexual reproductionGO:0019953360.064
inner ear morphogenesisGO:0042472630.063
positive regulation of nucleic acid templated transcriptionGO:1903508570.062
transcription dna templatedGO:00063511810.060
regulation of transcription from rna polymerase ii promoterGO:00063571140.060
hormone transportGO:000991420.059
regulation of rna biosynthetic processGO:20011412130.058
cytoskeleton organizationGO:0007010960.057
cellular protein metabolic processGO:00442671290.056
regulation of signalingGO:00230512350.055
nephron developmentGO:0072006310.054
single organism transportGO:00447652060.054
protein modification processGO:00362111000.053
reproductionGO:0000003400.053
gamete generationGO:0007276330.052
positive regulation of cell communicationGO:0010647560.052
kidney vasculature developmentGO:006144020.052
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:1900094170.051
nonmotile primary cilium assemblyGO:003505820.051
regulation of rna metabolic processGO:00512522240.050
pharyngeal muscle developmentGO:004328240.050
regulation of heart growthGO:006042020.050
endocardium morphogenesisGO:000316040.050
aromatic compound biosynthetic processGO:00194382170.049
bmp signaling pathway involved in heart joggingGO:0003303140.049
regulation of retina development in camera type eyeGO:190286620.048
positive regulation of signal transductionGO:0009967560.048
regulation of developmental processGO:00507932470.048
cellular component morphogenesisGO:00329893360.047
pronephros morphogenesisGO:0072114140.045
system processGO:00030081850.044
retina morphogenesis in camera type eyeGO:0060042790.044
pronephric glomerulus morphogenesisGO:003577560.044
homeostatic processGO:00425921420.042
positive regulation of macromolecule metabolic processGO:0010604930.042
eye developmentGO:00016542770.042
regulation of neurogenesisGO:0050767870.042
regulation of autophagyGO:001050630.042
establishment of localization in cellGO:0051649770.042
pericardium developmentGO:006003910.042
regulation of transmembrane transporter activityGO:002289820.042
regulation of anatomical structure sizeGO:0090066330.041
generation of neuronsGO:00486993850.041
cilium or flagellum dependent cell motilityGO:000153940.041
gene expressionGO:00104672520.041
otolith developmentGO:0048840320.040
negative regulation of biological processGO:00485193040.040
epithelial tube morphogenesisGO:00605621480.040
posterior lateral line system developmentGO:0048915460.040
regulation of neural retina developmentGO:006107420.039
regulation of phGO:000688530.038
cellular response to organic substanceGO:00713101050.038
kupffer s vesicle developmentGO:0070121500.037
endoderm developmentGO:0007492490.037
response to oxygen containing compoundGO:1901700550.037
vestibular receptor cell differentiationGO:006011430.037
ameboidal type cell migrationGO:00016671430.036
regulation of neuron differentiationGO:0045664560.036
pronephric glomerulus developmentGO:0039021130.036
axis specificationGO:0009798430.035
regulation of inner ear receptor cell differentiationGO:200098010.035
regulation of cell communicationGO:00106462320.035
semicircular canal morphogenesisGO:0048752180.035
photoreceptor cell differentiationGO:0046530550.035
embryonic skeletal system developmentGO:0048706970.034
positive regulation of transcription dna templatedGO:0045893570.034
regulation of ion transmembrane transporter activityGO:003241220.033
pronephric nephron tubule developmentGO:003902020.033
regulation of response to stimulusGO:00485832690.033
membrane repolarizationGO:008600920.033
cellular nitrogen compound biosynthetic processGO:00442712180.033
regulation of gene expressionGO:00104682650.033
posterior lateral line developmentGO:0048916380.033
positive regulation of nucleobase containing compound metabolic processGO:0045935690.033
cellular response to endogenous stimulusGO:0071495680.033
cellular response to nutrient levelsGO:003166920.033
mesoderm developmentGO:0007498880.032
axial mesoderm formationGO:004832040.032
growthGO:00400071740.032
positive regulation of embryonic developmentGO:004001930.031
nephron tubule epithelial cell differentiationGO:007216010.031
taxisGO:00423301090.031
neurotransmitter transportGO:000683620.031
response to endogenous stimulusGO:0009719830.031
organic cyclic compound metabolic processGO:19013603010.030
homeostasis of number of cellsGO:0048872620.030
cellular localizationGO:0051641970.030
central nervous system neuron differentiationGO:0021953740.030
stem cell differentiationGO:00488631170.030
single organism reproductive processGO:0044702400.030
negative regulation of oocyte developmentGO:006028320.029
tube closureGO:006060610.029
auditory receptor cell fate commitmentGO:000991240.028
kidney rudiment formationGO:007200330.028
ventral spinal cord interneuron fate commitmentGO:006057930.028
ear morphogenesisGO:0042471640.028
vasculature developmentGO:00019442780.028
hematopoietic or lymphoid organ developmentGO:00485341910.028
rna biosynthetic processGO:00327741810.028
hair cell differentiationGO:0035315320.028
regulation of neurotransmitter transportGO:005158810.028
negative regulation of blood vessel endothelial cell migrationGO:004353710.028
cellular response to hormone stimulusGO:0032870390.028
developmental programmed cell deathGO:001062340.027
positive regulation of purine nucleotide catabolic processGO:003312310.027
myelination of lateral line nerve axonsGO:004889750.027
regulation of cellular biosynthetic processGO:00313262450.026
heart morphogenesisGO:00030071560.026
glomerulus vasculature developmentGO:007201220.026
single organism organelle organizationGO:19025891990.026
regulation of microtubule based movementGO:006063230.026
Human
cellular response to starvationGO:000926710.025
synaptic vesicle localizationGO:009747910.025
regulation of cell proliferation involved in heart morphogenesisGO:200013620.025
cardiogenic plate morphogenesisGO:000314210.025
transmission of nerve impulseGO:0019226190.025
regulation of cell cycleGO:0051726520.025
protein complex biogenesisGO:0070271300.025
Human
cell fate commitment involved in formation of primary germ layerGO:0060795260.025
proximal tubule developmentGO:007201430.025
inner ear receptor stereocilium organizationGO:006012280.025
regulation of cellular protein metabolic processGO:0032268520.024
multicellular organismal signalingGO:0035637220.024
positive regulation of nucleoside metabolic processGO:004597910.024
smooth muscle tissue developmentGO:004874510.024
bmp signaling pathway involved in determination of left right symmetryGO:0003154140.024
positive regulation of nucleotide catabolic processGO:003081310.024
multicellular organismal reproductive processGO:0048609350.024
nucleic acid templated transcriptionGO:00976591810.023
skeletal system morphogenesisGO:00487051020.023
response to external stimulusGO:00096052640.023
response to organic cyclic compoundGO:0014070510.023
spemann organizer formation at the embryonic shieldGO:006006320.023
synaptic growth at neuromuscular junctionGO:005112420.023
neurotransmitter secretionGO:000726920.023
lateral line developmentGO:0048882660.023
neuromast developmentGO:0048884460.022
embryonic cranial skeleton morphogenesisGO:0048701900.022
positive regulation of transportGO:005105020.022
atrial ventricular junction remodelingGO:000329420.022
cell cycle processGO:0022402530.022
positive regulation of macromolecule biosynthetic processGO:0010557590.022
regulation of organ growthGO:004662030.022
synaptic transmission cholinergicGO:000727140.022
neural plate developmentGO:0001840100.022
mitotic cytokinesisGO:000028130.022
neuromuscular junction developmentGO:000752890.022
aorta developmentGO:003590440.022
microtubule cytoskeleton organizationGO:0000226330.022
formation of primary germ layerGO:0001704620.022
neuron projection guidanceGO:0097485860.022
embryonic skeletal joint developmentGO:007249830.021
regulation of multicellular organismal processGO:00512392770.021
response to organic substanceGO:00100331530.021
exocytosisGO:000688710.021
otic placode formationGO:0043049230.021
regulation of wnt signaling pathway calcium modulating pathwayGO:000859130.021
regulation of circadian rhythmGO:004275240.021
negative regulation of cell communicationGO:0010648960.021
photoreceptor cell fate specificationGO:004370410.020
positive regulation of metabolic processGO:00098931080.020
positive regulation of cellular catabolic processGO:003133130.020
agingGO:000756820.020
negative regulation of ras protein signal transductionGO:004658010.020
transcription from rna polymerase ii promoterGO:0006366800.020
regulation of transporter activityGO:003240920.020
embryonic heart tube developmentGO:00350501330.020
vestibular reflexGO:006000520.020
regulation of systemic arterial blood pressureGO:000307310.020
regulation of establishment of protein localizationGO:007020140.020
chemotaxisGO:00069351040.020
regulation of biological qualityGO:00650082630.020
otolith morphogenesisGO:003247480.020
cell fate specificationGO:0001708680.019
positive regulation of ras gtpase activityGO:003232010.019
spermatid developmentGO:000728620.019
regulation of system processGO:0044057400.019
regulation of cellular component organizationGO:0051128860.019
pancreas developmentGO:0031016840.018
Human
protein localizationGO:0008104400.018
neural crest cell migrationGO:0001755420.018
regulation of macromolecule biosynthetic processGO:00105562250.018
heterocycle metabolic processGO:00464832900.018
regulation of nervous system developmentGO:0051960900.018
retina homeostasisGO:0001895120.018
cellular response to external stimulusGO:007149620.018
vesicle localizationGO:0051648270.018
transportGO:00068102200.018
tissue homeostasisGO:0001894250.018
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.018
regulation of tube sizeGO:003515020.018
positive regulation of multicellular organismal processGO:0051240520.017
cellular response to oxygen containing compoundGO:1901701200.017
positive regulation of cellular metabolic processGO:0031325940.017
regulation of transcription dna templatedGO:00063552130.017
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.017
embryonic limb morphogenesisGO:003032620.017
forebrain regionalizationGO:002187140.017
cell deathGO:00082191210.017
cardiac atrium morphogenesisGO:000320920.017
mitotic cell cycle processGO:1903047480.016
synapse organizationGO:0050808210.016
regulation of cellular component movementGO:0051270550.016
Human
skeletal system developmentGO:00015011810.016
regulation of gtpase activityGO:004308720.016
cellular response to extracellular stimulusGO:003166820.016
regulation of mechanoreceptor differentiationGO:004563110.016
regulation of cell differentiationGO:00455951420.016
cell morphogenesis involved in neuron differentiationGO:00486671630.016
regulation of metabolic processGO:00192223590.016
nuclear transportGO:005116940.016
cell cell signalingGO:0007267520.016
ectodermal placode morphogenesisGO:0071697320.016
response to lipidGO:0033993600.016
axon developmentGO:00615641660.016
regulation of epithelial cell proliferationGO:005067830.016
positive regulation of signalingGO:0023056560.016
regulation of photoreceptor cell differentiationGO:004653220.015
immune system processGO:00023762410.015
immune system developmentGO:00025201910.015
peripheral nervous system developmentGO:0007422550.015
muscle cell differentiationGO:00426921390.015
thrombocyte differentiationGO:000257440.015
cardiac cell fate commitmentGO:006091110.015
regulation of molecular functionGO:0065009700.015
smoothened signaling pathwayGO:0007224300.015
regulation of nucleoside metabolic processGO:000911820.015
cellular response to growth factor stimulusGO:0071363390.015
organic substance biosynthetic processGO:19015762890.015
establishment of synaptic vesicle localizationGO:009748010.015
blood vessel developmentGO:00015682460.015
apoptotic process involved in developmentGO:190274220.015
wound healingGO:0042060900.015
ventral spinal cord interneuron differentiationGO:0021514120.014
cell cycleGO:0007049930.014
embryonic digestive tract morphogenesisGO:004855730.014
cell proliferation involved in heart morphogenesisGO:006132320.014
vestibular receptor cell developmentGO:006011830.014
photoreceptor cell fate commitmentGO:004655210.014
lateral line nerve glial cell morphogenesis involved in differentiationGO:004893850.014
cellular monovalent inorganic cation homeostasisGO:003000420.014
regulation of purine nucleotide catabolic processGO:003312120.014
cell migration involved in gastrulationGO:0042074790.014
muscle cell fate determinationGO:000752110.014
osteoclast developmentGO:003603510.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.014
multicellular organism growthGO:003526440.014
positive regulation of epithelial cell differentiationGO:003085820.014
posterior lateral line nerve glial cell morphogenesis involved in differentiationGO:004894250.014
regulation of multicellular organism growthGO:004001440.013
axon guidanceGO:0007411860.013
regulation of membrane potentialGO:0042391230.013
negative regulation of macromolecule metabolic processGO:0010605760.013
mechanosensory lateral line system developmentGO:0048881490.013
nucleobase containing compound biosynthetic processGO:00346542050.013
cellular process involved in reproduction in multicellular organismGO:0022412280.013
inner ear receptor cell developmentGO:0060119200.013
posterior lateral line nerve glial cell differentiationGO:004893150.013
fin regenerationGO:0031101510.013
regulation of tyrosine phosphorylation of stat3 proteinGO:004251610.013
retinal cone cell differentiationGO:0042670120.013
cell surface receptor signaling pathwayGO:00071663250.013
developmental growth involved in morphogenesisGO:0060560860.013
epithelial cell proliferationGO:0050673170.013
spermatid differentiationGO:004851520.013
positive regulation of gtpase activityGO:004354710.013
cell differentiation in spinal cordGO:0021515400.013
regulation of hormone secretionGO:004688320.013
regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:1901213150.013
reactive oxygen species metabolic processGO:007259360.013
regulation of gtp catabolic processGO:003312420.013
protein complex assemblyGO:0006461300.013
Human
blood circulationGO:0008015870.012
negative regulation of secretionGO:005104820.012
pectoral fin developmentGO:0033339500.012
negative regulation of gliogenesisGO:001401410.012
kidney epithelium developmentGO:0072073230.012
striated muscle cell differentiationGO:00511461290.012
specification of axis polarityGO:006500140.012
regulation of protein metabolic processGO:0051246560.012
floor plate formationGO:0021508120.012
embryonic skeletal system morphogenesisGO:0048704930.012
cellular macromolecule metabolic processGO:00442603910.012
nephron tubule developmentGO:007208040.012
regulation of oocyte developmentGO:006028130.012
hindbrain developmentGO:0030902910.012
negative regulation of stem cell differentiationGO:200073720.012
vasculogenesisGO:0001570410.012
regulation of cell shapeGO:000836010.012
cell maturationGO:0048469230.011
cell cycle g1 s phase transitionGO:004484310.011
pectoral fin morphogenesisGO:0035138290.011
venous endothelial cell migration involved in lymph vessel developmentGO:006085540.011
myelination of posterior lateral line nerve axonsGO:004893250.011
skeletal muscle fiber developmentGO:0048741350.011
circulatory system processGO:0003013870.011
regulation of anterior head developmentGO:200074220.011
endodermal cell fate specificationGO:0001714170.011
regulation of bmp signaling pathway involved in heart joggingGO:2000223120.011
mechanoreceptor differentiationGO:0042490370.011
bmp signaling pathway involved in heart developmentGO:0061312150.011
organelle localizationGO:0051640490.011
otic vesicle formationGO:0030916270.011
response to hexoseGO:000974630.011
otic vesicle morphogenesisGO:0071600340.011
palate developmentGO:006002180.011
regulation of response to external stimulusGO:0032101310.011
guanosine containing compound metabolic processGO:190106840.011
positive regulation of cgmp metabolic processGO:003082560.011
positive regulation of gtp catabolic processGO:003312610.011
cytokinesisGO:000091030.011
positive regulation of fibroblast growth factor receptor signaling pathwayGO:004574390.010
positive regulation of response to stimulusGO:0048584800.010
morphogenesis of embryonic epitheliumGO:0016331300.010
small gtpase mediated signal transductionGO:000726480.010
developmental process involved in reproductionGO:0003006270.010
nephron epithelium developmentGO:0072009160.010
semicircular canal developmentGO:0060872240.010
autophagyGO:000691440.010
protein localization to nucleusGO:003450430.010
regionalizationGO:00030022740.010
Human
hormone secretionGO:004687920.010
gliogenesisGO:0042063450.010
regulation of cytokine productionGO:000181730.010

lrrc50 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
kidney diseaseDOID:55700.036
urinary system diseaseDOID:1800.036
disease of anatomical entityDOID:700.036
disease of cellular proliferationDOID:1456600.020
organ system cancerDOID:005068600.020
urinary system cancerDOID:399600.020
cancerDOID:16200.020