Danio rerio

60 known processes

gmds

GDP-mannose 4,6-dehydratase

(Aliases: MGC63772,zgc:63772,si:ch211-231n5.3,dZ84G17.1)

gmds biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mechanosensory lateral line system developmentGO:0048881490.816
axon developmentGO:00615641660.559
signal transductionGO:00071654550.550
neuron developmentGO:00486662620.516
cellular component movementGO:00069283350.473
digestive tract morphogenesisGO:00485462310.378
cell projection morphogenesisGO:00488582440.343
taxisGO:00423301090.334
regulation of biological qualityGO:00650082630.303
neuron differentiationGO:00301823530.291
cellular macromolecule metabolic processGO:00442603910.265
cell projection organizationGO:00300302840.262
generation of neuronsGO:00486993850.258
digestive tract developmentGO:00485652650.239
neuron projection developmentGO:00311751800.234
regulation of signal transductionGO:00099662250.230
morphogenesis of an epitheliumGO:00020093330.214
chemotaxisGO:00069351040.211
negative regulation of biological processGO:00485193040.208
response to chemicalGO:00422213200.207
Worm
regulation of synaptic growth at neuromuscular junctionGO:000858210.198
cell morphogenesis involved in differentiationGO:00009041950.195
neuron projection morphogenesisGO:00488121610.188
axonogenesisGO:00074091520.187
response to external stimulusGO:00096052640.187
actin filament based processGO:0030029640.184
Worm
cellular component assembly involved in morphogenesisGO:00109271070.169
Worm
negative regulation of cellular processGO:00485232830.168
sensory organ developmentGO:00074233930.160
organelle assemblyGO:00709251100.160
Worm
regulation of multicellular organismal developmentGO:20000262230.159
lateral line system developmentGO:0048925760.158
larval developmentGO:000216420.155
Worm
cell migrationGO:00164772370.155
positive regulation of cellular processGO:00485222010.152
biological adhesionGO:0022610400.151
cell motilityGO:00488702440.149
posterior lateral line system developmentGO:0048915460.140
neuron projection guidanceGO:0097485860.137
ameboidal type cell migrationGO:00016671430.135
embryonic organ developmentGO:00485683810.129
locomotionGO:00400113130.123
Worm
convergent extension involved in gastrulationGO:0060027710.119
regulation of response to stimulusGO:00485832690.114
cell morphogenesisGO:00009022890.113
cell fate commitmentGO:0045165990.111
vasculature developmentGO:00019442780.109
cell part morphogenesisGO:00329902460.106
localization of cellGO:00516742440.103
lateral line developmentGO:0048882660.102
regulation of developmental processGO:00507932470.099
cell morphogenesis involved in neuron differentiationGO:00486671630.096
muscle cell developmentGO:00550011150.095
Worm
regulation of neurogenesisGO:0050767870.092
heart loopingGO:0001947940.091
heart developmentGO:00075073130.090
homeostatic processGO:00425921420.090
multi organism processGO:00517041340.090
Worm
brain developmentGO:00074202930.088
blood vessel morphogenesisGO:00485142160.087
single organism localizationGO:19025782250.083
hemopoiesisGO:00300971830.082
positive regulation of cellular component biogenesisGO:004408930.082
tube morphogenesisGO:00352393490.081
regulation of cell differentiationGO:00455951420.079
gastrulationGO:00073692080.078
cell surface receptor signaling pathwayGO:00071663250.076
negative regulation of multicellular organismal processGO:0051241690.076
biosynthetic processGO:00090582940.073
Worm
central nervous system developmentGO:00074173870.072
cellular component assemblyGO:00226071700.071
Worm
erythrocyte differentiationGO:0030218540.069
myeloid cell homeostasisGO:0002262560.067
maternal determination of anterior posterior axis embryoGO:000835840.065
response to stressGO:00069502630.063
Worm
convergent extensionGO:00600261180.063
neuron migrationGO:0001764220.060
blood vessel developmentGO:00015682460.060
cellular component morphogenesisGO:00329893360.058
Worm
regulation of signalingGO:00230512350.058
regulation of cell developmentGO:00602841000.058
muscle structure developmentGO:00610611960.057
Worm
gtp metabolic processGO:004603940.057
stem cell proliferationGO:007208940.056
chordate embryonic developmentGO:00430092710.053
regulation of anatomical structure morphogenesisGO:00226031300.052
regulation of multicellular organismal processGO:00512392770.052
erythrocyte homeostasisGO:0034101550.051
regulation of cell projection assemblyGO:006049140.050
fertilizationGO:000956630.050
regulation of synapse organizationGO:005080730.049
agingGO:000756820.049
transportGO:00068102200.048
heart morphogenesisGO:00030071560.047
cell adhesionGO:0007155400.047
stem cell divisionGO:001714510.047
spindle assembly involved in mitosisGO:009030710.045
regulation of synaptic plasticityGO:004816710.045
regulation of synapse assemblyGO:005196330.045
regulation of nervous system developmentGO:0051960900.045
camera type eye developmentGO:00430102220.043
nerve developmentGO:0021675450.043
meiotic nuclear divisionGO:000712640.043
organelle organizationGO:00069962270.042
Worm
peripheral nervous system developmentGO:0007422550.042
exocytosisGO:000688710.042
angiogenesisGO:00015251580.041
dorsal ventral pattern formationGO:00099531250.041
embryonic organ morphogenesisGO:00485622740.041
regulation of endothelial cell proliferationGO:000193610.040
cilium organizationGO:0044782710.040
specification of symmetryGO:00097992040.039
embryo development ending in birth or egg hatchingGO:00097922710.039
auditory receptor cell morphogenesisGO:000209340.039
central nervous system neuron differentiationGO:0021953740.039
neuroblast proliferationGO:000740520.038
regulation of gene expressionGO:00104682650.038
cellular response to chemical stimulusGO:00708871570.038
Worm
aromatic compound biosynthetic processGO:00194382170.038
Worm
polarized epithelial cell differentiationGO:003085940.038
canonical wnt signaling pathwayGO:0060070480.037
tissue migrationGO:0090130370.037
single organism carbohydrate metabolic processGO:0044723120.036
forebrain generation of neuronsGO:0021872140.036
multi organism reproductive processGO:0044703360.036
Worm
stem cell maintenanceGO:001982740.036
forebrain developmentGO:0030900960.036
positive regulation of signal transductionGO:0009967560.035
cranial nerve developmentGO:0021545420.035
regulation of cellular component organizationGO:0051128860.035
regulation of cell communicationGO:00106462320.035
cell migration involved in gastrulationGO:0042074790.035
single organism metabolic processGO:00447102170.035
single organism cellular localizationGO:1902580460.034
behaviorGO:0007610740.034
Worm
regulation of primary metabolic processGO:00800903110.034
epithelium migrationGO:0090132250.033
sensory system developmentGO:0048880760.033
cellular component biogenesisGO:00440851780.033
Worm
establishment of epithelial cell apical basal polarityGO:004519820.033
epithelial cell migrationGO:0010631250.033
regulation of glial cell differentiationGO:004568540.033
growthGO:00400071740.033
regulation of mrna processingGO:005068430.032
regulation of wnt signaling pathwayGO:0030111530.032
formation of primary germ layerGO:0001704620.032
spindle assemblyGO:005122520.032
digestive system developmentGO:00551232890.032
single organismal cell cell adhesionGO:0016337290.031
embryonic heart tube morphogenesisGO:00031431080.031
oocyte anterior posterior axis specificationGO:000731440.031
diencephalon developmentGO:0021536580.031
regulation of ectoderm developmentGO:200038320.031
cell deathGO:00082191210.031
embryonic heart tube developmentGO:00350501330.031
glycoprotein biosynthetic processGO:0009101210.030
g protein coupled receptor signaling pathwayGO:0007186740.030
actomyosin structure organizationGO:0031032530.030
Worm
head developmentGO:00603223030.030
determination of left right symmetryGO:00073681790.030
regulation of oligodendrocyte differentiationGO:004871310.030
reproductionGO:0000003400.029
Worm
muscle cell differentiationGO:00426921390.029
Worm
medulla oblongata developmentGO:002155040.029
cellular localizationGO:0051641970.028
protein importGO:001703830.028
wnt signaling pathwayGO:0016055800.028
regulation of cellular metabolic processGO:00313233200.028
positive regulation of transportGO:005105020.028
organelle localizationGO:0051640490.028
regulation of macromolecule metabolic processGO:00602553170.028
regulation of response to cytokine stimulusGO:006075930.027
gliogenesisGO:0042063450.027
meiotic cell cycle processGO:190304630.027
regulation of muscle contractionGO:000693730.027
immune system developmentGO:00025201910.026
cellular nitrogen compound metabolic processGO:00346412900.026
Worm
deathGO:00162651210.026
immune system processGO:00023762410.026
positive regulation of signalingGO:0023056560.026
anatomical structure arrangementGO:004853220.026
multicellular organismal signalingGO:0035637220.026
developmental growthGO:00485891660.026
homeostasis of number of cellsGO:0048872620.026
apoptotic processGO:00069151160.025
mitochondrion organizationGO:000700540.025
protein import into nucleusGO:000660630.025
astrocyte differentiationGO:004870810.025
single fertilizationGO:000733830.025
cytoskeleton organizationGO:0007010960.025
Worm
receptor recyclingGO:000188140.025
regulation of stem cell differentiationGO:200073640.024
regulation of reproductive processGO:200024140.024
phosphorylationGO:0016310690.024
maintenance of locationGO:005123540.024
epithelial cell morphogenesisGO:000338220.024
posterior lateral line developmentGO:0048916380.024
protein glycosylationGO:000648690.024
erk1 and erk2 cascadeGO:007037140.024
cell junction organizationGO:0034330110.024
regulation of cellular amine metabolic processGO:003323800.024
notch signaling pathwayGO:0007219350.023
cellular biosynthetic processGO:00442492860.023
Worm
central nervous system neuron developmentGO:0021954290.023
phagocytosisGO:000690930.023
regulation of embryonic developmentGO:0045995470.023
system processGO:00030081850.023
negative regulation of nervous system developmentGO:0051961220.023
ribonucleoside monophosphate catabolic processGO:000915840.023
guanosine containing compound metabolic processGO:190106840.023
regionalizationGO:00030022740.023
female sex differentiationGO:004666040.023
single organism transportGO:00447652060.023
cellular amino acid metabolic processGO:000652070.023
ectodermal cell fate specificationGO:000171520.023
glial cell differentiationGO:0010001420.022
regulation of glucose importGO:004632410.022
protein modification processGO:00362111000.022
striated muscle cell developmentGO:00550021080.022
Worm
cellular protein modification processGO:00064641000.022
negative regulation of signalingGO:0023057960.022
nuclear exportGO:005116810.021
regulation of multicellular organism growthGO:004001440.021
developmental maturationGO:0021700340.021
cellular amine metabolic processGO:004410620.021
regulation of cellular amino acid metabolic processGO:000652100.021
dorsal motor nucleus of vagus nerve developmentGO:002174440.021
actin filament based movementGO:003004810.021
posterior lateral line neuromast developmentGO:0048919200.021
epithelial tube morphogenesisGO:00605621480.021
actin cytoskeleton organizationGO:0030036630.021
Worm
cellular ketone metabolic processGO:0042180110.021
cellular aromatic compound metabolic processGO:00067252950.021
Worm
axon guidanceGO:0007411860.020
pole plasm assemblyGO:000731540.020
lipid storageGO:001991510.020
neurotransmitter transportGO:000683620.020
cardiac muscle tissue developmentGO:0048738480.020
small molecule metabolic processGO:0044281770.020
Worm
regulation of peptidyl tyrosine phosphorylationGO:005073010.020
cellular protein metabolic processGO:00442671290.020
regulation of neuron differentiationGO:0045664560.020
protein targeting to nucleusGO:004474430.020
cell proliferationGO:0008283800.019
macromolecule glycosylationGO:004341390.019
regulation of neuron projection developmentGO:0010975400.019
negative regulation of kinase activityGO:003367340.019
cellular process involved in reproduction in multicellular organismGO:0022412280.019
pigment cell differentiationGO:0050931380.019
negative regulation of response to stimulusGO:00485851040.019
microtubule cytoskeleton organization involved in mitosisGO:190285010.019
nitrogen compound metabolic processGO:00068073190.019
Worm
gtp catabolic processGO:000618420.019
negative regulation of synapse assemblyGO:005196420.019
cellular macromolecule biosynthetic processGO:00346452240.019
regulation of tube sizeGO:003515020.019
negative regulation of metabolic processGO:0009892860.018
notochord developmentGO:0030903540.018
erythrocyte developmentGO:0048821240.018
positive regulation of epithelial cell migrationGO:001063420.018
negative regulation of developmental processGO:0051093650.018
single organism reproductive processGO:0044702400.018
regulation of microtubule depolymerizationGO:003111410.018
epithelial cell differentiationGO:00308551160.018
photoreceptor cell differentiationGO:0046530550.018
oxoacid metabolic processGO:0043436310.018
inner ear receptor cell fate commitmentGO:006012040.018
protein metabolic processGO:00195381830.018
regulation of cell shapeGO:000836010.018
regulation of phosphorylationGO:0042325260.018
carboxylic acid metabolic processGO:0019752220.017
rna localizationGO:000640340.017
response to glucocorticoidGO:005138410.017
organic substance transportGO:0071702580.017
heart processGO:0003015710.017
positive regulation of cell cycleGO:004578730.017
establishment of epithelial cell polarityGO:009016220.017
neuroblast fate commitmentGO:001401710.017
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.017
negative regulation of cell differentiationGO:0045596460.017
regulation of eye photoreceptor cell developmentGO:004247820.017
spermatid differentiationGO:004851520.017
adherens junction organizationGO:003433240.017
epidermal cell differentiationGO:0009913360.017
establishment of monopolar cell polarityGO:006116220.017
macromolecule modificationGO:00434121110.017
regulation of cell proliferation involved in heart morphogenesisGO:200013620.017
determination of bilateral symmetryGO:00098552040.016
synaptic growth at neuromuscular junctionGO:005112420.016
cell cycle processGO:0022402530.016
eye morphogenesisGO:00485921440.016
regulation of developmental growthGO:0048638380.016
macromolecular complex disassemblyGO:003298410.016
programmed cell deathGO:00125011190.016
tube closureGO:006060610.016
stem cell fate commitmentGO:004886510.016
regulation of cell morphogenesisGO:0022604420.016
response to woundingGO:00096111160.016
centrosome organizationGO:005129710.016
macromolecule localizationGO:0033036540.016
nucleocytoplasmic transportGO:000691340.016
mesoderm developmentGO:0007498880.016
regulation of epithelial to mesenchymal transitionGO:001071730.016
establishment of apical basal cell polarityGO:003508920.016
cellular response to oxygen levelsGO:007145310.016
cell junction maintenanceGO:003433120.016
cell growthGO:0016049570.016
anterior posterior pattern specificationGO:00099521520.015
multicellular organismal reproductive processGO:0048609350.015
Worm
membrane fusionGO:006102520.015
regulation of receptor recyclingGO:000191930.015
negative regulation of protein kinase activityGO:000646940.015
positive regulation of blood circulationGO:190352420.015
guanosine containing compound catabolic processGO:190106920.015
cellular response to external stimulusGO:007149620.015
neuroblast differentiationGO:001401610.015
regulation of circadian rhythmGO:004275240.015
i kappab kinase nf kappab signalingGO:000724940.015
protein localization to nucleusGO:003450430.015
positive regulation of catabolic processGO:000989640.015
negative regulation of gene expressionGO:0010629650.015
regulation of cell projection organizationGO:0031344440.015
amine metabolic processGO:000930820.015
protein homooligomerizationGO:005126030.015
establishment of synaptic vesicle localizationGO:009748010.015
response to drugGO:004249330.015
forebrain cell migrationGO:002188510.015
positive regulation of gliogenesisGO:001401520.015
regulation of nucleoside metabolic processGO:000911820.015
developmental growth involved in morphogenesisGO:0060560860.014
intracellular signal transductionGO:0035556850.014
cellular response to nutrient levelsGO:003166920.014
regulation of apoptotic processGO:0042981980.014
fin morphogenesisGO:0033334530.014
protein complex disassemblyGO:004324110.014
auditory receptor cell differentiationGO:0042491150.014
primitive hemopoiesisGO:0060215270.014
autophagyGO:000691440.014
regulation of blood vessel sizeGO:005088020.014
morphogenesis of an epithelial sheetGO:0002011490.014
regulation of cellular ketone metabolic processGO:001056570.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
regulation of blood pressureGO:000821710.014
cellular response to decreased oxygen levelsGO:003629410.014
carbohydrate derivative metabolic processGO:1901135610.014
Worm
regulation of cell deathGO:00109411030.014
cell cell junction organizationGO:0045216100.013
cellular response to hypoxiaGO:007145610.013
striated muscle cell differentiationGO:00511461290.013
Worm
primary neural tube formationGO:001402010.013
sexual reproductionGO:0019953360.013
cell recognitionGO:0008037190.013
cellular response to starvationGO:000926710.013
neuron projection extensionGO:1990138450.013
protein complex assemblyGO:0006461300.013
Worm
actin mediated cell contractionGO:007025210.013
axonal fasciculationGO:0007413110.013
pigment cell developmentGO:007028530.013
regulation of wnt signaling pathway involved in heart developmentGO:000330720.013
negative regulation of epithelial cell proliferationGO:005068010.013
protein complex localizationGO:003150310.013
adherens junction maintenanceGO:003433420.013
stem cell differentiationGO:00488631170.013
cellular response to stressGO:0033554620.013
Worm
septum transversum developmentGO:000334340.013
cellular response to extracellular stimulusGO:003166820.013
cytoskeleton dependent cytokinesisGO:006164030.013
nuclear importGO:005117030.013
regulation of cellular biosynthetic processGO:00313262450.012
auditory receptor cell developmentGO:006011780.012
embryonic skeletal joint developmentGO:007249830.012
organ formationGO:0048645170.012
blood circulationGO:0008015870.012
regulation of striated muscle contractionGO:000694220.012
positive regulation of response to stimulusGO:0048584800.012
positive regulation of canonical wnt signaling pathwayGO:009026340.012
response to light stimulusGO:0009416460.012
regulation of macromolecule biosynthetic processGO:00105562250.012
protein localizationGO:0008104400.012
gene expressionGO:00104672520.012
phosphorus metabolic processGO:00067931090.012
Worm
heart formationGO:0060914130.012
single organism organelle organizationGO:19025891990.012
Worm
cation transportGO:0006812810.012
cellular component disassemblyGO:002241110.012
single organism membrane fusionGO:004480120.012
regulation of biosynthetic processGO:00098892500.012
proepicardium developmentGO:000334240.012
intracellular mrna localizationGO:000829810.012
myeloid cell differentiationGO:0030099860.012
macromolecule biosynthetic processGO:00090592270.012
motor neuron migrationGO:009747540.012
positive regulation of biological processGO:00485182530.012
nucleobase containing compound biosynthetic processGO:00346542050.012
Worm
neurotransmitter secretionGO:000726920.012
glial cell migrationGO:000834730.012
establishment of localization in cellGO:0051649770.012
regulation of receptor mediated endocytosisGO:004825940.012
positive regulation of ras protein signal transductionGO:004657910.012
regulation of cell proliferationGO:0042127370.012
small gtpase mediated signal transductionGO:000726480.012
odontogenesis of dentin containing toothGO:004247510.012
regulation of cell motilityGO:2000145460.012
negative chemotaxisGO:005091910.012
regenerationGO:0031099910.012
endoderm formationGO:0001706290.012
regulation of establishment of protein localizationGO:007020140.012
regulation of membrane potentialGO:0042391230.012
organonitrogen compound metabolic processGO:1901564740.012
synaptic vesicle localizationGO:009747910.012
cell proliferation involved in heart morphogenesisGO:006132320.012
mitotic cell cycle embryonicGO:004544820.011
regulation of epithelial cell proliferationGO:005067830.011
neurological system processGO:0050877620.011
cellular carbohydrate metabolic processGO:004426240.011
cytokinesisGO:000091030.011
cellular nitrogen compound biosynthetic processGO:00442712180.011
Worm
multicellular organism growthGO:003526440.011
regulation of axonogenesisGO:0050770320.011
regulation of organ growthGO:004662030.011
establishment or maintenance of apical basal cell polarityGO:0035088120.011
cardiac conduction system developmentGO:000316110.011
embryonic axis specificationGO:0000578120.011
somatic stem cell maintenanceGO:003501910.011
establishment of localizationGO:00512342440.011
epidermis developmentGO:0008544480.011
regulation of stem cell proliferationGO:007209120.011
regulation of blood coagulationGO:003019310.011
fatty acid biosynthetic processGO:000663340.011
protein localization to membraneGO:007265790.011
transmission of nerve impulseGO:0019226190.011
cranial nerve morphogenesisGO:0021602150.011
response to corticosteroidGO:003196010.011
regulation of metabolic processGO:00192223590.011
mitotic cell cycle processGO:1903047480.011
antimicrobial humoral responseGO:001973020.011
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.011
mitochondrial transportGO:000683920.011
establishment of protein localization to organelleGO:007259440.011
hair cell differentiationGO:0035315320.010
regulation of cytoplasmic transportGO:190364940.010
positive regulation of developmental processGO:0051094500.010
somite developmentGO:0061053960.010
cardiac cell fate commitmentGO:006091110.010
positive regulation of glucose transportGO:001082810.010
striated muscle contractionGO:0006941120.010
cytoplasm organizationGO:000702840.010
transcription dna templatedGO:00063511810.010
positive regulation of cellular catabolic processGO:003133130.010
ras protein signal transductionGO:000726570.010
positive regulation of neuron deathGO:190121610.010
establishment of protein localization to plasma membraneGO:009000210.010
establishment or maintenance of bipolar cell polarityGO:0061245120.010
cell cell adhesion involved in mesendodermal cell migrationGO:000337010.010
proximal distal pattern formationGO:000995410.010
regulation of i kappab kinase nf kappab signalingGO:004312240.010
endoderm developmentGO:0007492490.010

gmds disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
muscular diseaseDOID:008000000.023
musculoskeletal system diseaseDOID:1700.023
muscle tissue diseaseDOID:6600.023
myopathyDOID:42300.021
intrinsic cardiomyopathyDOID:006003600.016
cardiovascular system diseaseDOID:128700.016
heart diseaseDOID:11400.016
cardiomyopathyDOID:005070000.016
nonsyndromic deafnessDOID:005056300.015
sensory system diseaseDOID:005015500.015
auditory system diseaseDOID:274200.015
nervous system diseaseDOID:86300.015
immune system diseaseDOID:291400.012
autosomal dominant nonsyndromic deafnessDOID:005056400.012
disease of metabolismDOID:001466700.011
inherited metabolic disorderDOID:65500.010
lysosomal storage diseaseDOID:321100.010