Danio rerio

0 known processes

usp12a

ubiquitin specific peptidase 12a

(Aliases: usp12,sb:eu882,MGC136837,wu:fi09d12)

usp12a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.465
agingGO:000756820.191
cellular nitrogen compound metabolic processGO:00346412900.153
cellular aromatic compound metabolic processGO:00067252950.126
cellular protein catabolic processGO:004425740.098
regulation of developmental processGO:00507932470.096
organic cyclic compound metabolic processGO:19013603010.086
nucleobase containing compound metabolic processGO:00061392740.083
protein importGO:001703830.082
establishment of protein localization to organelleGO:007259440.082
regulation of peptidyl tyrosine phosphorylationGO:005073010.080
nuclear transportGO:005116940.080
single organism organelle organizationGO:19025891990.079
signal transductionGO:00071654550.078
nitrogen compound metabolic processGO:00068073190.077
positive regulation of biological processGO:00485182530.076
protein metabolic processGO:00195381830.073
heterocycle metabolic processGO:00464832900.072
cellular macromolecule metabolic processGO:00442603910.072
single organism metabolic processGO:00447102170.068
fertilizationGO:000956630.067
amine metabolic processGO:000930820.067
organelle organizationGO:00069962270.066
regulation of macromolecule metabolic processGO:00602553170.066
regulation of response to stimulusGO:00485832690.065
heart developmentGO:00075073130.064
organic cyclic compound biosynthetic processGO:19013622230.064
regulation of protein import into nucleusGO:004230620.063
single fertilizationGO:000733830.063
nuclear importGO:005117030.062
regulation of protein ubiquitinationGO:003139630.059
regulation of signalingGO:00230512350.056
small molecule metabolic processGO:0044281770.055
protein import into nucleusGO:000660630.054
organic substance biosynthetic processGO:19015762890.054
regulation of cellular amine metabolic processGO:003323800.054
regulation of rna metabolic processGO:00512522240.054
regulation of nitrogen compound metabolic processGO:00511712510.054
cognitionGO:005089010.053
neuron differentiationGO:00301823530.053
regionalizationGO:00030022740.052
regulation of nucleobase containing compound metabolic processGO:00192192500.052
rna metabolic processGO:00160702190.052
biosynthetic processGO:00090582940.052
nucleocytoplasmic transportGO:000691340.051
regulation of signal transductionGO:00099662250.051
heterocycle biosynthetic processGO:00181302150.051
gene expressionGO:00104672520.051
regulation of establishment of protein localizationGO:007020140.050
regulation of cellular amino acid metabolic processGO:000652100.050
positive regulation of cellular metabolic processGO:0031325940.050
compound eye developmentGO:004874920.050
regulation of primary metabolic processGO:00800903110.049
single organism nuclear importGO:190259330.049
cell surface receptor signaling pathwayGO:00071663250.049
regulation of metabolic processGO:00192223590.049
cell morphogenesis involved in differentiationGO:00009041950.048
regulation of protein modification by small protein conjugation or removalGO:190332030.048
cellular biosynthetic processGO:00442492860.048
regulation of cellular metabolic processGO:00313233200.047
cell projection organizationGO:00300302840.046
cellular amine metabolic processGO:004410620.046
aromatic compound biosynthetic processGO:00194382170.046
negative regulation of cytoplasmic transportGO:190365020.046
sensory organ developmentGO:00074233930.045
regulation of transcription dna templatedGO:00063552130.045
proteolysis involved in cellular protein catabolic processGO:005160330.045
regulation of cytoplasmic transportGO:190364940.045
lipid storageGO:001991510.045
cytokinesisGO:000091030.044
cellular component movementGO:00069283350.044
negative regulation of kinase activityGO:003367340.044
cellular component morphogenesisGO:00329893360.044
nucleic acid metabolic processGO:00903042440.043
regulation of intracellular protein transportGO:003315730.043
locomotor rhythmGO:004547530.043
nuclear migrationGO:000709730.043
pole plasm assemblyGO:000731540.043
embryo development ending in birth or egg hatchingGO:00097922710.043
regulation of synapse organizationGO:005080730.042
negative regulation of biological processGO:00485193040.042
regulation of cellular ketone metabolic processGO:001056570.042
small gtpase mediated signal transductionGO:000726480.042
cellular ketone metabolic processGO:0042180110.041
single organism localizationGO:19025782250.041
synaptic growth at neuromuscular junctionGO:005112420.040
protein targeting to nucleusGO:004474430.040
positive regulation of transportGO:005105020.039
protein dephosphorylationGO:000647030.039
adult behaviorGO:003053420.039
generation of neuronsGO:00486993850.039
multicellular organism growthGO:003526440.039
regulation of protein complex assemblyGO:004325430.038
cellular protein metabolic processGO:00442671290.038
cell agingGO:000756920.038
macromolecule biosynthetic processGO:00090592270.038
single organism transportGO:00447652060.038
regulation of biosynthetic processGO:00098892500.038
positive regulation of cellular processGO:00485222010.038
regulation of multicellular organism growthGO:004001440.038
regulation of multicellular organismal processGO:00512392770.037
cell morphogenesisGO:00009022890.037
endosomal transportGO:001619720.037
establishment of localizationGO:00512342440.036
protein localization to nucleusGO:003450430.036
phosphorus metabolic processGO:00067931090.036
eye developmentGO:00016542770.036
positive regulation of catabolic processGO:000989640.036
negative regulation of response to stimulusGO:00485851040.035
phosphate containing compound metabolic processGO:00067961080.035
intracellular mrna localizationGO:000829810.035
maintenance of locationGO:005123540.035
cellular amino acid metabolic processGO:000652070.034
regulation of protein targetingGO:190353320.034
negative regulation of protein kinase activityGO:000646940.034
cellular component biogenesisGO:00440851780.034
regulation of protein transportGO:005122330.033
rna localizationGO:000640340.033
regulation of rna biosynthetic processGO:20011412130.033
microtubule based processGO:0007017600.032
carboxylic acid metabolic processGO:0019752220.032
positive regulation of cellular amino acid metabolic processGO:004576400.032
negative regulation of protein phosphorylationGO:000193340.032
regulation of cell differentiationGO:00455951420.032
positive regulation of cellular amine metabolic processGO:003324000.031
negative regulation of map kinase activityGO:004340720.031
stem cell proliferationGO:007208940.030
neuron developmentGO:00486662620.030
macromolecule modificationGO:00434121110.030
positive regulation of cellular catabolic processGO:003133130.030
locomotionGO:00400113130.030
homeostatic processGO:00425921420.030
regulation of synaptic growth at neuromuscular junctionGO:000858210.030
neuron projection developmentGO:00311751800.030
negative regulation of cellular processGO:00485232830.029
cellular component assemblyGO:00226071700.029
regulation of macromolecule biosynthetic processGO:00105562250.029
negative regulation of nucleocytoplasmic transportGO:004682320.029
pronuclear migrationGO:003504610.029
golgi vesicle transportGO:004819330.029
regulation of purine nucleotide catabolic processGO:003312120.029
organic acid metabolic processGO:0006082310.029
neuron projection morphogenesisGO:00488121610.029
protein polyubiquitinationGO:000020940.029
organic substance transportGO:0071702580.029
negative regulation of protein localization to nucleusGO:190018120.028
macromolecule localizationGO:0033036540.028
organonitrogen compound metabolic processGO:1901564740.028
nucleic acid templated transcriptionGO:00976591810.028
phosphorylationGO:0016310690.028
protein polymerizationGO:005125840.028
transcription dna templatedGO:00063511810.028
stem cell maintenanceGO:001982740.027
mitochondrion organizationGO:000700540.027
regulation of multicellular organismal developmentGO:20000262230.027
sleepGO:003043110.027
positive regulation of cell cycleGO:004578730.027
regulation of cellular macromolecule biosynthetic processGO:20001122220.027
axonogenesisGO:00074091520.027
regulation of molecular functionGO:0065009700.027
regulation of circadian rhythmGO:004275240.026
cytoskeleton dependent cytokinesisGO:006164030.026
central nervous system neuron differentiationGO:0021953740.026
negative regulation of metabolic processGO:0009892860.026
establishment of synaptic vesicle localizationGO:009748010.026
regulation of nucleocytoplasmic transportGO:004682220.026
development of primary female sexual characteristicsGO:004654540.026
rna biosynthetic processGO:00327741810.026
response to drugGO:004249330.026
regulation of dendrite developmentGO:005077330.026
response to stressGO:00069502630.026
regulation of nervous system developmentGO:0051960900.026
cellular nitrogen compound biosynthetic processGO:00442712180.026
autophagyGO:000691440.026
phagocytosisGO:000690930.026
cellular macromolecule biosynthetic processGO:00346452240.025
germ line stem cell maintenanceGO:003071820.025
modification dependent protein catabolic processGO:001994130.025
regulation of cell activationGO:005086510.025
extrinsic apoptotic signaling pathwayGO:009719130.025
regulation of gene expressionGO:00104682650.025
peptidyl threonine phosphorylationGO:001810710.025
intracellular signal transductionGO:0035556850.025
regulation of protein localization to nucleusGO:190018020.024
negative regulation of protein serine threonine kinase activityGO:007190120.024
negative regulation of signal transductionGO:0009968940.024
regulation of cell communicationGO:00106462320.024
oxoacid metabolic processGO:0043436310.024
negative regulation of protein import into nucleusGO:004230820.024
regulation of catalytic activityGO:0050790550.024
regulation of oocyte developmentGO:006028130.024
neuron neuron synaptic transmissionGO:000727010.024
morphogenesis of an epitheliumGO:00020093330.024
negative regulation of intracellular protein transportGO:009031730.024
negative regulation of signalingGO:0023057960.024
regulation of cell shapeGO:000836010.023
transportGO:00068102200.023
protein acetylationGO:000647320.023
ubiquitin dependent protein catabolic processGO:000651130.023
cell projection morphogenesisGO:00488582440.023
nucleobase containing compound biosynthetic processGO:00346542050.023
regulation of biological qualityGO:00650082630.023
positive regulation of metabolic processGO:00098931080.023
response to abiotic stimulusGO:00096281220.023
cellular localizationGO:0051641970.023
vasculature developmentGO:00019442780.022
spermatid developmentGO:000728620.022
modification dependent macromolecule catabolic processGO:004363230.022
regulation of neurological system processGO:003164420.022
centrosome organizationGO:005129710.022
stem cell divisionGO:001714510.022
response to chemicalGO:00422213200.022
regulation of gtp catabolic processGO:003312420.022
regulation of reproductive processGO:200024140.022
cellular response to nutrient levelsGO:003166920.022
cellular response to external stimulusGO:007149620.022
somatic muscle developmentGO:000752540.022
peptidyl serine phosphorylationGO:001810510.022
synaptic vesicle localizationGO:009747910.022
cell substrate adhesionGO:003158940.022
negative regulation of intracellular transportGO:003238730.022
stem cell developmentGO:0048864820.022
positive regulation of purine nucleotide catabolic processGO:003312310.022
regulation of nucleotide catabolic processGO:003081120.021
regulation of cellular protein metabolic processGO:0032268520.021
ras protein signal transductionGO:000726570.021
nucleoside monophosphate catabolic processGO:000912540.021
protein acylationGO:004354330.021
response to alkaloidGO:004327920.021
spermatid differentiationGO:004851520.020
forebrain cell migrationGO:002188510.020
mononuclear cell proliferationGO:003294310.020
meiotic nuclear divisionGO:000712640.020
ion transportGO:00068111140.020
female sex differentiationGO:004666040.020
positive regulation of nucleotide catabolic processGO:003081310.020
immune system processGO:00023762410.020
system processGO:00030081850.020
lateral inhibitionGO:004633110.020
immune system developmentGO:00025201910.020
proteasomal protein catabolic processGO:001049820.020
regulation of reactive oxygen species metabolic processGO:200037720.020
protein modification processGO:00362111000.020
cell maturationGO:0048469230.020
positive regulation of cell divisionGO:005178120.020
mitotic cell cycleGO:0000278640.020
negative regulation of protein complex assemblyGO:003133310.019
digestive system developmentGO:00551232890.019
oocyte developmentGO:0048599140.019
negative regulation of protein transportGO:005122430.019
positive regulation of gtp catabolic processGO:003312610.019
dicarboxylic acid transportGO:000683510.019
peptidyl threonine modificationGO:001821010.019
cellular response to chemical stimulusGO:00708871570.019
cell migrationGO:00164772370.019
regulation of protein metabolic processGO:0051246560.019
chordate embryonic developmentGO:00430092710.019
regulation of phosphate metabolic processGO:0019220430.019
synaptic vesicle transportGO:004848910.019
regulation of nucleoside metabolic processGO:000911820.019
internal protein amino acid acetylationGO:000647520.019
axon developmentGO:00615641660.019
centrosome cycleGO:000709810.019
atp catabolic processGO:000620040.019
positive regulation of gtpase activityGO:004354710.018
organelle localizationGO:0051640490.018
post golgi vesicle mediated transportGO:000689210.018
regulation of neural precursor cell proliferationGO:200017730.018
regulation of synapse assemblyGO:005196330.018
membrane invaginationGO:001032410.018
neuroblast proliferationGO:000740520.018
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.018
peptidyl serine modificationGO:001820920.018
protein homooligomerizationGO:005126030.018
cell deathGO:00082191210.018
regulation of i kappab kinase nf kappab signalingGO:004312240.018
negative regulation of mapk cascadeGO:004340940.018
histone h3 k4 methylationGO:005156820.018
actin polymerization or depolymerizationGO:000815420.018
gtp metabolic processGO:004603940.018
mitotic cytokinesisGO:000028130.018
axis specificationGO:0009798430.018
regulation of dendrite morphogenesisGO:004881430.018
cellular response to radiationGO:007147840.018
negative regulation of reproductive processGO:200024230.018
protein localization to plasma membraneGO:007265910.018
maternal determination of anterior posterior axis embryoGO:000835840.017
regulation of gtpase activityGO:004308720.017
negative regulation of cellular biosynthetic processGO:0031327550.017
positive regulation of cellular component biogenesisGO:004408930.017
developmental maturationGO:0021700340.017
purine ribonucleoside monophosphate catabolic processGO:000916940.017
phagocytosis engulfmentGO:000691110.017
response to fluid shear stressGO:003440520.017
dorsal ventral pattern formationGO:00099531250.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
gtp catabolic processGO:000618420.017
positive regulation of nucleoside metabolic processGO:004597910.017
i kappab kinase nf kappab signalingGO:000724940.017
hemopoiesisGO:00300971830.017
multi organism processGO:00517041340.017
regulation of anatomical structure morphogenesisGO:00226031300.017
leukocyte proliferationGO:007066110.017
positive regulation of stem cell proliferationGO:200064810.017
regulation of cell developmentGO:00602841000.017
cellular response to extracellular stimulusGO:003166820.016
positive regulation of chromosome organizationGO:200125210.016
cellular response to starvationGO:000926710.016
b cell activationGO:004211320.016
spindle assemblyGO:005122520.016
oocyte differentiationGO:0009994140.016
regulation of cell substrate adhesionGO:001081010.016
female gonad developmentGO:000858540.016
intracellular transportGO:0046907320.016
blood vessel developmentGO:00015682460.016
cytoskeleton organizationGO:0007010960.016
secondary metabolic processGO:001974830.016
cytoplasm organizationGO:000702840.016
epithelial cell differentiationGO:00308551160.016
hatchingGO:003518840.016
regulation of rho protein signal transductionGO:003502320.016
regulation of neurogenesisGO:0050767870.016
response to uvGO:000941130.016
regulation of cellular biosynthetic processGO:00313262450.016
positive regulation of chromatin modificationGO:190331010.016
cellular component disassemblyGO:002241110.016
neuromuscular synaptic transmissionGO:000727420.016
adherens junction organizationGO:003433240.016
regulation of synaptic plasticityGO:004816710.016
actin filament polymerizationGO:003004120.016
mitotic g2 m transition checkpointGO:004481830.015
negative regulation of nitrogen compound metabolic processGO:0051172590.015
positive regulation of i kappab kinase nf kappab signalingGO:004312330.015
ribonucleoside monophosphate catabolic processGO:000915840.015
oocyte anterior posterior axis specificationGO:000731440.015
regulation of bindingGO:005109830.015
mitochondrial transportGO:000683920.015
macromolecular complex subunit organizationGO:0043933740.015
organism emergence from protective structureGO:007168440.015
sensory perception of painGO:001923310.015
meiotic chromosome segregationGO:004513230.014
microtubule organizing center organizationGO:003102310.014
digestive tract developmentGO:00485652650.014
regulation of protein catabolic processGO:004217610.014
guanosine containing compound metabolic processGO:190106840.014
macromolecular complex disassemblyGO:003298410.014
small molecule catabolic processGO:004428230.014
mitotic dna integrity checkpointGO:004477440.014
segmentationGO:0035282970.014
cell part morphogenesisGO:00329902460.014
peptidyl lysine acetylationGO:001839420.014
locomotory behaviorGO:0007626340.014
regulation of wnt signaling pathwayGO:0030111530.014
blood vessel morphogenesisGO:00485142160.014
centrosome duplicationGO:005129810.014
hormone secretionGO:004687920.014
wnt signaling pathwayGO:0016055800.014
protein complex disassemblyGO:004324110.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
purine nucleoside monophosphate catabolic processGO:000912840.014
response to hydrogen peroxideGO:004254230.014
regulation of stem cell proliferationGO:007209120.014
cellular carbohydrate metabolic processGO:004426240.013
positive regulation of stress activated mapk cascadeGO:003287430.013
cellular protein modification processGO:00064641000.013
localization of cellGO:00516742440.013
regulation of organ growthGO:004662030.013
circadian sleep wake cycle processGO:002241020.013
regulation of cytokine productionGO:000181730.013
establishment of localization in cellGO:0051649770.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.013
lymphocyte proliferationGO:004665110.013
positive regulation of response to stimulusGO:0048584800.013
cell cycle arrestGO:000705010.013
establishment of organelle localizationGO:0051656450.013
negative regulation of synapse assemblyGO:005196420.013
regulation of epithelial cell proliferationGO:005067830.013
mitotic g2 dna damage checkpointGO:000709530.013
sex determinationGO:000753010.013
cation transportGO:0006812810.013
oocyte constructionGO:000730850.013
negative regulation of nucleobase containing compound metabolic processGO:0045934590.013
neurotransmitter transportGO:000683620.013
growthGO:00400071740.013
negative regulation of macromolecule metabolic processGO:0010605760.013
central nervous system developmentGO:00074173870.013
positive regulation of histone modificationGO:003105810.013
lipid catabolic processGO:001604240.013
positive regulation of map kinase activityGO:004340630.013
membrane fusionGO:006102520.013
positive regulation of protein complex assemblyGO:003133420.013
regulation of ion transmembrane transporter activityGO:003241220.013
protein targeting to membraneGO:000661210.013
guanosine containing compound catabolic processGO:190106920.013
protein phosphorylationGO:0006468470.013
protein secretionGO:000930610.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
meiotic cell cycle processGO:190304630.013
sphingolipid biosynthetic processGO:003014820.013
apoptotic processGO:00069151160.013
negative regulation of catabolic processGO:000989530.013
cellular lipid catabolic processGO:004424230.013
regulation of cellular component organizationGO:0051128860.012
response to nutrientGO:000758430.012
regulation of neuron differentiationGO:0045664560.012
positive regulation of cell activationGO:005086710.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
regulation of meiotic cell cycleGO:005144510.012
alcohol biosynthetic processGO:004616520.012
regulation of protein polymerizationGO:003227120.012
internal peptidyl lysine acetylationGO:001839320.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
regulation of mrna processingGO:005068430.012
ovulation cycleGO:004269820.012
positive regulation of lipid metabolic processGO:004583410.012
regulation of dna templated transcription in response to stressGO:004362000.012
regulation of receptor activityGO:001046920.012
developmental growthGO:00485891660.012
negative regulation of cellular metabolic processGO:0031324770.012
regulation of sodium ion transportGO:000202820.012
positive regulation of neural precursor cell proliferationGO:200017910.012
multi organism reproductive processGO:0044703360.012
regulation of intracellular signal transductionGO:1902531570.012
response to organic substanceGO:00100331530.012
regulation of cell projection organizationGO:0031344440.012
developmental programmed cell deathGO:001062340.011
circadian sleep wake cycle sleepGO:005080210.011
forebrain developmentGO:0030900960.011
rna transportGO:005065820.011
gastrulationGO:00073692080.011
neurotransmitter secretionGO:000726920.011
nucleobase containing compound transportGO:001593120.011
positive regulation of macromolecule metabolic processGO:0010604930.011
microtubule cytoskeleton organizationGO:0000226330.011
single organism cellular localizationGO:1902580460.011
regulation of programmed cell deathGO:00430671010.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
cellular respirationGO:004533330.011
thermosensory behaviorGO:004004010.011
negative regulation of ras protein signal transductionGO:004658010.011
anterior posterior pattern specificationGO:00099521520.011
regulation of transporter activityGO:003240920.011
ameboidal type cell migrationGO:00016671430.011
erk1 and erk2 cascadeGO:007037140.011
endocrine processGO:005088620.011
regulation of metal ion transportGO:001095940.011
response to temperature stimulusGO:0009266150.011
gland developmentGO:00487321430.011
multicellular organismal macromolecule metabolic processGO:004425920.011
cellular amide metabolic processGO:004360340.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
regulation of protein modification processGO:0031399290.011
regulation of erk1 and erk2 cascadeGO:007037240.011
biological adhesionGO:0022610400.011
macroautophagyGO:001623610.011
dna templated transcription elongationGO:000635430.011
negative regulation of cell deathGO:0060548600.011
carboxylic acid catabolic processGO:004639530.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
regulation of ras gtpase activityGO:003231820.011
cellular response to endogenous stimulusGO:0071495680.011
cellular component maintenanceGO:004395430.011
photoreceptor cell differentiationGO:0046530550.011
positive regulation of molecular functionGO:0044093330.011
tube closureGO:006060610.011
positive regulation of small gtpase mediated signal transductionGO:005105710.011
response to endogenous stimulusGO:0009719830.011
regulation of lipid transportGO:003236840.011
multicellular organismal metabolic processGO:004423620.011
protein localizationGO:0008104400.010
stem cell differentiationGO:00488631170.010
taxisGO:00423301090.010
cell motilityGO:00488702440.010
oxidoreduction coenzyme metabolic processGO:000673310.010
cilium organizationGO:0044782710.010
regulation of chromosome segregationGO:005198310.010
skin developmentGO:0043588540.010
amino acid transportGO:000686520.010
embryonic organ developmentGO:00485683810.010
carbohydrate homeostasisGO:003350010.010
glucose homeostasisGO:004259310.010

usp12a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.062
nervous system diseaseDOID:86300.023
disease of metabolismDOID:001466700.012
musculoskeletal system diseaseDOID:1700.012
eye and adnexa diseaseDOID:149200.012
sensory system diseaseDOID:005015500.012
eye diseaseDOID:561400.012
central nervous system diseaseDOID:33100.011
neurodegenerative diseaseDOID:128900.011
myopathyDOID:42300.011
muscle tissue diseaseDOID:6600.011
muscular diseaseDOID:008000000.011
disease of cellular proliferationDOID:1456600.010
cancerDOID:16200.010