Danio rerio

0 known processes

hmgb1b

high-mobility group box 1b

(Aliases: MGC165618,wu:fb13a05,wu:fa96c07,zgc:165618)

hmgb1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
3 utr mediated mrna stabilizationGO:007093530.959
regulation of bindingGO:005109830.546
Human
rna stabilizationGO:004348940.533
b cell differentiationGO:003018310.357
extrinsic apoptotic signaling pathwayGO:009719130.343
regulation of nuclease activityGO:003206910.341
nucleic acid templated transcriptionGO:00976591810.292
Human Mouse
cellular aromatic compound metabolic processGO:00067252950.234
Human Mouse
negative regulation of leukocyte differentiationGO:190210610.208
response to coldGO:000940940.201
negative regulation of macromolecule biosynthetic processGO:0010558480.197
Human
organic cyclic compound metabolic processGO:19013603010.184
Human Mouse
regulation of transcription dna templatedGO:00063552130.176
Human Mouse
regulation of rna biosynthetic processGO:20011412130.174
Human Mouse
regulation of gene expressionGO:00104682650.148
Human Mouse
positive regulation of cell cycleGO:004578730.132
spermatid differentiationGO:004851520.126
organic cyclic compound biosynthetic processGO:19013622230.113
Human Mouse
regulation of cellular metabolic processGO:00313233200.111
Human Mouse
negative regulation of nucleobase containing compound metabolic processGO:0045934590.110
Human
regulation of mrna splicing via spliceosomeGO:004802430.106
cellular macromolecule biosynthetic processGO:00346452240.104
Human Mouse
response to external stimulusGO:00096052640.104
response to uvGO:000941130.103
myeloid cell differentiationGO:0030099860.100
Mouse
regulation of nitrogen compound metabolic processGO:00511712510.100
Human Mouse
regulation of hematopoietic progenitor cell differentiationGO:190153210.098
positive regulation of nuclease activityGO:003207510.096
muscle structure developmentGO:00610611960.094
response to other organismGO:0051707970.090
response to external biotic stimulusGO:0043207970.089
response to vitaminGO:003327330.089
cellular component movementGO:00069283350.087
negative regulation of myeloid cell differentiationGO:004563810.085
cellular component biogenesisGO:00440851780.080
Human
cellular nitrogen compound biosynthetic processGO:00442712180.078
Human Mouse
macromolecule biosynthetic processGO:00090592270.077
Human Mouse
regulation of cellular macromolecule biosynthetic processGO:20001122220.076
Human Mouse
positive regulation of transportGO:005105020.073
negative regulation of rna biosynthetic processGO:1902679450.072
Human
nucleobase containing compound biosynthetic processGO:00346542050.071
Human Mouse
regulation of neural precursor cell proliferationGO:200017730.068
cytoskeleton dependent cytokinesisGO:006164030.065
aromatic compound biosynthetic processGO:00194382170.064
Human Mouse
nucleic acid metabolic processGO:00903042440.063
Human Mouse
nucleobase containing compound metabolic processGO:00061392740.062
Human Mouse
melanin metabolic processGO:000658220.062
response to chemicalGO:00422213200.061
Mouse
cell proliferationGO:0008283800.061
organelle organizationGO:00069962270.060
cell cycle processGO:0022402530.058
regulation of cell activationGO:005086510.058
b cell activationGO:004211320.058
organic substance biosynthetic processGO:19015762890.054
Human Mouse
smoothened signaling pathwayGO:0007224300.054
negative regulation of ras protein signal transductionGO:004658010.054
response to temperature stimulusGO:0009266150.054
startle responseGO:000196440.053
negative regulation of biosynthetic processGO:0009890550.051
Human
biosynthetic processGO:00090582940.051
Human Mouse
regulation of erythrocyte differentiationGO:004564620.050
regulation of cellular biosynthetic processGO:00313262450.050
Human Mouse
regulation of myeloid cell differentiationGO:004563780.049
Mouse
regulation of multicellular organismal developmentGO:20000262230.048
Mouse
rna transportGO:005065820.047
negative regulation of cellular biosynthetic processGO:0031327550.046
Human
negative regulation of nitrogen compound metabolic processGO:0051172590.045
Human
peptidyl lysine acetylationGO:001839420.045
negative regulation of gene expressionGO:0010629650.045
Human
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.045
regulation of immune system processGO:0002682340.045
Mouse
signal transductionGO:00071654550.044
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.044
regulation of response to stimulusGO:00485832690.043
negative regulation of signalingGO:0023057960.042
regulation of mrna stabilityGO:004348840.042
cellular component morphogenesisGO:00329893360.042
alternative mrna splicing via spliceosomeGO:000038010.042
negative regulation of rna metabolic processGO:0051253480.042
Human
eye developmentGO:00016542770.041
Mouse
regulation of biosynthetic processGO:00098892500.041
Human Mouse
mitotic cell cycle processGO:1903047480.040
cellular response to chemical stimulusGO:00708871570.040
mitotic cytokinesisGO:000028130.040
regulation of oligodendrocyte differentiationGO:004871310.040
negative regulation of biological processGO:00485193040.040
Human Mouse
spermatid developmentGO:000728620.040
positive regulation of neural precursor cell proliferationGO:200017910.039
cognitionGO:005089010.038
nucleic acid transportGO:005065720.037
cellular biosynthetic processGO:00442492860.036
Human Mouse
muscle tissue developmentGO:00605371100.036
cell cycleGO:0007049930.035
embryonic digestive tract developmentGO:004856640.035
striated muscle tissue developmentGO:00147061100.035
rna splicingGO:0008380160.034
cellular response to organic substanceGO:00713101050.034
cell surface receptor signaling pathwayGO:00071663250.033
rna metabolic processGO:00160702190.033
Human Mouse
regulation of apoptotic processGO:0042981980.033
Human
cytokinesisGO:000091030.033
larval developmentGO:000216420.032
axon developmentGO:00615641660.032
nuclear body organizationGO:003057520.032
regulation of cell communicationGO:00106462320.032
sensory organ developmentGO:00074233930.031
Mouse
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377100.031
regulation of endothelial cell proliferationGO:000193610.031
female gonad developmentGO:000858540.030
embryonic digestive tract morphogenesisGO:004855730.030
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.029
regulation of epithelial cell proliferationGO:005067830.029
heterocycle biosynthetic processGO:00181302150.028
Human Mouse
regulation of programmed cell deathGO:00430671010.028
Human
determination of left right symmetryGO:00073681790.028
single organism organelle organizationGO:19025891990.028
cellular response to molecule of bacterial originGO:007121930.028
establishment of rna localizationGO:005123630.028
hemopoiesisGO:00300971830.027
Mouse
stem cell proliferationGO:007208940.027
positive regulation of biological processGO:00485182530.027
Human Mouse
regulation of reproductive processGO:200024140.027
signal transduction in absence of ligandGO:003803410.027
cell part morphogenesisGO:00329902460.027
erythrocyte differentiationGO:0030218540.026
stem cell maintenanceGO:001982740.026
chemotaxisGO:00069351040.026
response to lipidGO:0033993600.026
Mouse
mrna stabilizationGO:004825540.026
protein acylationGO:004354330.026
cellular response to lipidGO:0071396390.026
positive regulation of multi organism processGO:004390230.026
regulation of protein bindingGO:004339330.026
megakaryocyte differentiationGO:003021910.025
positive regulation of reproductive processGO:200024320.025
protein acetylationGO:000647320.025
adult behaviorGO:003053420.025
cell projection organizationGO:00300302840.025
hematopoietic progenitor cell differentiationGO:0002244230.025
regulation of nucleic acid templated transcriptionGO:19035062130.024
Human Mouse
sister chromatid cohesionGO:000706220.024
negative regulation of cellular processGO:00485232830.024
Human
regulation of nucleotide catabolic processGO:003081120.024
carboxylic acid metabolic processGO:0019752220.024
positive regulation of immune effector processGO:000269930.023
heart loopingGO:0001947940.023
regulation of signal transductionGO:00099662250.023
development of primary female sexual characteristicsGO:004654540.023
retina layer formationGO:0010842240.023
positive regulation of nucleotide catabolic processGO:003081310.023
negative regulation of programmed cell deathGO:0043069580.022
mitochondrion organizationGO:000700540.022
female germ line stem cell maintenanceGO:003609910.022
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.022
Human
multi organism processGO:00517041340.022
negative regulation of signal transductionGO:0009968940.022
gtp metabolic processGO:004603940.022
organic acid metabolic processGO:0006082310.022
nucleus organizationGO:000699770.022
neuroblast proliferationGO:000740520.021
positive regulation of cytosolic calcium ion concentrationGO:000720440.021
cellular response to external stimulusGO:007149620.021
positive chemotaxisGO:005091850.021
regulation of myelinationGO:003164110.021
regulation of production of molecular mediator of immune responseGO:000270010.021
negative regulation of response to stimulusGO:00485851040.020
covalent chromatin modificationGO:0016569200.020
translational initiationGO:000641330.020
cellular nitrogen compound metabolic processGO:00346412900.020
Human Mouse
protein localization to plasma membraneGO:007265910.020
head developmentGO:00603223030.020
nitrogen compound metabolic processGO:00068073190.020
Human Mouse
response to glucocorticoidGO:005138410.020
Mouse
rna export from nucleusGO:000640510.019
determination of bilateral symmetryGO:00098552040.019
regulation of mrna processingGO:005068430.019
negative regulation of apoptotic processGO:0043066550.019
negative regulation of transcription dna templatedGO:0045892450.019
Human
response to virusGO:0009615210.019
cilium morphogenesisGO:0060271850.019
meiotic nuclear divisionGO:000712640.019
cell cycle g1 s phase transitionGO:004484310.018
meiotic cell cycle processGO:190304630.018
embryonic organ developmentGO:00485683810.018
negative regulation of cell communicationGO:0010648960.018
cytoskeleton organizationGO:0007010960.018
aorta developmentGO:003590440.018
mrna metabolic processGO:0016071200.018
guanosine containing compound metabolic processGO:190106840.017
cellular response to oxygen containing compoundGO:1901701200.017
ubiquitin dependent protein catabolic processGO:000651130.017
immunoglobulin productionGO:000237710.017
positive regulation of hydrolase activityGO:0051345130.017
Human
regulation of muscle contractionGO:000693730.017
atrioventricular valve developmentGO:0003171110.017
brain morphogenesisGO:0048854180.017
cell projection morphogenesisGO:00488582440.017
epithelial cell differentiationGO:00308551160.017
negative regulation of cell deathGO:0060548600.016
oxidation reduction processGO:0055114410.016
Mouse
modification of morphology or physiology of other organismGO:003582140.016
regulation of response to biotic stimulusGO:000283120.016
cellular response to organic cyclic compoundGO:0071407380.016
regulation of macromolecule biosynthetic processGO:00105562250.016
Human Mouse
negative regulation of nucleic acid templated transcriptionGO:1903507450.016
Human
regulation of purine nucleotide catabolic processGO:003312120.016
neural retina developmentGO:0003407490.016
positive regulation of cellular metabolic processGO:0031325940.016
Human Mouse
positive regulation of cellular catabolic processGO:003133130.016
Mouse
stem cell developmentGO:0048864820.016
internal peptidyl lysine acetylationGO:001839320.016
positive regulation of striated muscle cell differentiationGO:005115510.016
regulation of cell cycleGO:0051726520.016
negative regulation of metabolic processGO:0009892860.016
Human
hematopoietic or lymphoid organ developmentGO:00485341910.016
Mouse
dorsal ventral pattern formationGO:00099531250.016
microtubule based processGO:0007017600.016
regulation of transcription from rna polymerase ii promoterGO:00063571140.015
Human Mouse
histone modificationGO:0016570200.015
purine nucleoside monophosphate catabolic processGO:000912840.015
positive regulation of epithelial cell differentiationGO:003085820.015
regulation of molecular functionGO:0065009700.015
Human Mouse
ribosomal small subunit biogenesisGO:004227420.015
morphogenesis of an epitheliumGO:00020093330.015
central nervous system neuron differentiationGO:0021953740.015
cell cycle g2 m phase transitionGO:004483940.015
embryonic cranial skeleton morphogenesisGO:0048701900.015
deathGO:00162651210.015
Human
negative regulation of cellular metabolic processGO:0031324770.015
Human
positive regulation of nitrogen compound metabolic processGO:0051173690.015
Human Mouse
central nervous system developmentGO:00074173870.014
response to oxygen containing compoundGO:1901700550.014
internal protein amino acid acetylationGO:000647520.014
regulation of signalingGO:00230512350.014
regulation of rna splicingGO:004348480.014
positive regulation of response to stimulusGO:0048584800.014
exocrine pancreas developmentGO:0031017280.014
locomotionGO:00400113130.014
neuron developmentGO:00486662620.014
ribose phosphate metabolic processGO:0019693270.014
viral processGO:001603210.013
cell deathGO:00082191210.013
Human
actin polymerization or depolymerizationGO:000815420.013
response to biotic stimulusGO:0009607970.013
regulation of multicellular organismal processGO:00512392770.013
Mouse
response to organic cyclic compoundGO:0014070510.013
Mouse
mitotic cell cycle embryonicGO:004544820.013
nucleotide metabolic processGO:0009117280.013
astrocyte differentiationGO:004870810.013
regulation of catalytic activityGO:0050790550.013
Human Mouse
mesenchymal cell proliferationGO:001046310.013
positive regulation of secretionGO:005104710.013
positive regulation of secretion by cellGO:190353210.013
cellular response to oxygen levelsGO:007145310.013
cellular macromolecule metabolic processGO:00442603910.012
Human Mouse
growthGO:00400071740.012
rna localizationGO:000640340.012
positive regulation of carbohydrate metabolic processGO:004591310.012
Mouse
chromatin modificationGO:0016568210.012
dendrite guidanceGO:007098300.012
dorsal aorta developmentGO:003590740.012
intra s dna damage checkpointGO:003157310.012
response to organic substanceGO:00100331530.012
Mouse
endomembrane system organizationGO:0010256130.012
small molecule catabolic processGO:004428230.012
retinal cell programmed cell deathGO:004666620.012
leukocyte differentiationGO:0002521250.012
positive regulation of gastrulationGO:200054320.012
regulation of intracellular protein transportGO:003315730.011
negative regulation of dna metabolic processGO:005105340.011
mesenchyme developmentGO:00604851270.011
response to hexoseGO:000974630.011
determination of heart left right asymmetryGO:00613711170.011
camera type eye developmentGO:00430102220.011
positive regulation of neuron apoptotic processGO:004352510.011
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.011
atp catabolic processGO:000620040.010
regulation of cytoplasmic transportGO:190364940.010
microtubule cytoskeleton organizationGO:0000226330.010
lateral inhibitionGO:004633110.010
cellular component assemblyGO:00226071700.010
Human
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.010
nucleobase containing compound transportGO:001593120.010
cardiac atrium morphogenesisGO:000320920.010
carbohydrate derivative metabolic processGO:1901135610.010
cell death in response to oxidative stressGO:003647320.010
response to endogenous stimulusGO:0009719830.010
Mouse

hmgb1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
physical disorderDOID:008001500.111
disease of cellular proliferationDOID:1456600.021
cancerDOID:16200.021
congenital nervous system abnormalityDOID:249000.017
lissencephalyDOID:005045300.012
organ system cancerDOID:005068600.011
central nervous system diseaseDOID:33100.011
disease of anatomical entityDOID:700.011
motor neuron diseaseDOID:23100.011
neurodegenerative diseaseDOID:128900.011
nervous system diseaseDOID:86300.011
amyotrophic lateral sclerosisDOID:33200.011