Danio rerio

0 known processes

LOC100000500

sclerostin-like

LOC100000500 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
skeletal system morphogenesisGO:00487051020.659
embryonic organ developmentGO:00485683810.654
chordate embryonic developmentGO:00430092710.600
embryonic viscerocranium morphogenesisGO:0048703520.588
embryonic skeletal system morphogenesisGO:0048704930.527
connective tissue developmentGO:0061448990.459
cellular nitrogen compound biosynthetic processGO:00442712180.438
embryonic skeletal system developmentGO:0048706970.431
skeletal system developmentGO:00015011810.430
embryo development ending in birth or egg hatchingGO:00097922710.345
regulation of transcription dna templatedGO:00063552130.293
embryonic organ morphogenesisGO:00485622740.292
sensory organ morphogenesisGO:00905962000.290
regulation of multicellular organismal processGO:00512392770.263
embryonic cranial skeleton morphogenesisGO:0048701900.244
cartilage development involved in endochondral bone morphogenesisGO:006035180.241
negative regulation of biological processGO:00485193040.238
sensory organ developmentGO:00074233930.233
regulation of gene expressionGO:00104682650.211
cartilage developmentGO:0051216960.207
digestive tract developmentGO:00485652650.200
cell surface receptor signaling pathwayGO:00071663250.200
heterocycle biosynthetic processGO:00181302150.198
cartilage morphogenesisGO:0060536130.181
transcription dna templatedGO:00063511810.179
regulation of cellular macromolecule biosynthetic processGO:20001122220.174
mesoderm morphogenesisGO:0048332510.167
regulation of metabolic processGO:00192223590.163
nucleobase containing compound biosynthetic processGO:00346542050.161
nucleic acid templated transcriptionGO:00976591810.159
regulation of nitrogen compound metabolic processGO:00511712510.150
bone morphogenesisGO:0060349110.150
heart developmentGO:00075073130.144
cellular macromolecule metabolic processGO:00442603910.143
macromolecule biosynthetic processGO:00090592270.139
regulation of nucleobase containing compound metabolic processGO:00192192500.132
regulation of signalingGO:00230512350.129
signal transductionGO:00071654550.126
morphogenesis of an epitheliumGO:00020093330.121
regulation of cellular biosynthetic processGO:00313262450.119
regulation of multicellular organismal developmentGO:20000262230.112
growth plate cartilage developmentGO:000341720.110
nitrogen compound metabolic processGO:00068073190.109
regulation of developmental processGO:00507932470.107
positive regulation of canonical wnt signaling pathwayGO:009026340.104
cellular component morphogenesisGO:00329893360.101
blood vessel developmentGO:00015682460.095
cellular macromolecule biosynthetic processGO:00346452240.094
system processGO:00030081850.093
regulation of cellular metabolic processGO:00313233200.092
regulation of nucleic acid templated transcriptionGO:19035062130.092
rna biosynthetic processGO:00327741810.088
inner ear developmentGO:00488391260.088
kidney developmentGO:0001822920.087
determination of left right symmetryGO:00073681790.086
regulation of macromolecule metabolic processGO:00602553170.086
fin regenerationGO:0031101510.086
cell morphogenesisGO:00009022890.085
olfactory bulb developmentGO:002177240.085
response to external stimulusGO:00096052640.080
regulation of signal transductionGO:00099662250.080
regulation of response to stimulusGO:00485832690.079
chondrocyte developmentGO:000206340.079
developmental growthGO:00485891660.079
mesoderm formationGO:0001707430.074
aromatic compound biosynthetic processGO:00194382170.073
regulation of anatomical structure morphogenesisGO:00226031300.072
notch signaling pathwayGO:0007219350.071
negative regulation of gene expressionGO:0010629650.071
cellular component movementGO:00069283350.070
regulation of epithelial to mesenchymal transitionGO:001071730.069
cardiac chamber morphogenesisGO:0003206120.068
protein metabolic processGO:00195381830.068
regulation of rna metabolic processGO:00512522240.067
cellular response to chemical stimulusGO:00708871570.067
organic cyclic compound biosynthetic processGO:19013622230.067
negative regulation of macromolecule metabolic processGO:0010605760.064
cellular biosynthetic processGO:00442492860.064
neurological system processGO:0050877620.063
response to chemicalGO:00422213200.063
determination of bilateral symmetryGO:00098552040.062
auditory receptor cell fate commitmentGO:000991240.062
negative regulation of cellular processGO:00485232830.061
organic substance biosynthetic processGO:19015762890.061
rna metabolic processGO:00160702190.060
angiogenesisGO:00015251580.059
notochord developmentGO:0030903540.059
pectoral fin developmentGO:0033339500.059
regulation of biosynthetic processGO:00098892500.059
central nervous system developmentGO:00074173870.058
negative regulation of signalingGO:0023057960.058
negative regulation of cell communicationGO:0010648960.057
locomotionGO:00400113130.056
regulation of gastrulationGO:0010470240.055
negative regulation of signal transductionGO:0009968940.053
negative regulation of metabolic processGO:0009892860.053
regulation of primary metabolic processGO:00800903110.053
tissue regenerationGO:0042246740.052
central nervous system neuron differentiationGO:0021953740.052
biosynthetic processGO:00090582940.051
heterocycle metabolic processGO:00464832900.051
neuron differentiationGO:00301823530.050
embryonic digestive tract morphogenesisGO:004855730.049
positive regulation of cellular processGO:00485222010.049
blood coagulationGO:0007596120.048
cellular nitrogen compound metabolic processGO:00346412900.048
inner ear receptor cell fate commitmentGO:006012040.048
sulfur compound metabolic processGO:0006790130.048
positive regulation of transcription dna templatedGO:0045893570.047
positive regulation of cell differentiationGO:0045597300.047
regionalizationGO:00030022740.047
adult behaviorGO:003053420.047
regulation of embryonic developmentGO:0045995470.046
positive regulation of signal transductionGO:0009967560.045
positive regulation of stem cell proliferationGO:200064810.044
positive regulation of response to stimulusGO:0048584800.044
wound healingGO:0042060900.044
embryonic digestive tract developmentGO:004856640.043
dorsal ventral pattern formationGO:00099531250.043
nucleobase containing compound metabolic processGO:00061392740.043
negative regulation of response to stimulusGO:00485851040.043
gabaergic neuron differentiationGO:009715420.042
protein importGO:001703830.042
protein targeting to nucleusGO:004474430.042
carboxylic acid metabolic processGO:0019752220.041
enzyme linked receptor protein signaling pathwayGO:00071671060.041
regulation of cell communicationGO:00106462320.041
cellular aromatic compound metabolic processGO:00067252950.040
collagen fibril organizationGO:003019910.040
embryonic limb morphogenesisGO:003032620.040
positive regulation of biosynthetic processGO:0009891680.040
agingGO:000756820.040
olfactory lobe developmentGO:002198840.039
ossificationGO:0001503230.039
regulation of extrinsic apoptotic signaling pathwayGO:200123630.039
regulation of mesenchymal cell proliferationGO:001046410.039
organic cyclic compound metabolic processGO:19013603010.039
ectodermal placode developmentGO:0071696370.039
heart morphogenesisGO:00030071560.038
nuclear transportGO:005116940.038
response to organic substanceGO:00100331530.038
protein import into nucleusGO:000660630.037
endochondral bone growthGO:000341620.036
positive regulation of nitrogen compound metabolic processGO:0051173690.036
negative regulation of cellular metabolic processGO:0031324770.035
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.035
regulation of reproductive processGO:200024140.035
inner ear morphogenesisGO:0042472630.035
digestive system developmentGO:00551232890.035
cranial suture morphogenesisGO:006036310.034
forebrain developmentGO:0030900960.034
response to woundingGO:00096111160.033
urogenital system developmentGO:0001655970.033
blood vessel morphogenesisGO:00485142160.033
positive regulation of nucleic acid templated transcriptionGO:1903508570.033
growth plate cartilage morphogenesisGO:000342210.033
catechol containing compound metabolic processGO:000971220.033
regulation of cell developmentGO:00602841000.033
cell projection organizationGO:00300302840.033
single organism metabolic processGO:00447102170.033
specification of organ identityGO:001009220.033
gastrulationGO:00073692080.032
vasculature developmentGO:00019442780.032
extrinsic apoptotic signaling pathwayGO:009719130.032
transcription from rna polymerase ii promoterGO:0006366800.032
anterior posterior pattern specificationGO:00099521520.032
glomerulus developmentGO:0032835270.032
regulation of locomotionGO:0040012550.032
positive regulation of mesenchymal cell proliferationGO:000205310.031
fin developmentGO:0033333770.031
taxisGO:00423301090.031
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.031
mesenchymal cell proliferationGO:001046310.031
developmental growth involved in morphogenesisGO:0060560860.031
tube morphogenesisGO:00352393490.031
circulatory system processGO:0003013870.031
endoderm developmentGO:0007492490.030
appendage developmentGO:0048736800.030
regulation of rna biosynthetic processGO:20011412130.030
nucleic acid metabolic processGO:00903042440.030
negative regulation of protein phosphorylationGO:000193340.030
regulation of mesodermal cell fate specificationGO:004266190.029
regulation of macromolecule biosynthetic processGO:00105562250.029
negative regulation of nitrogen compound metabolic processGO:0051172590.029
ear developmentGO:00435831270.029
epidermis developmentGO:0008544480.029
regulation of meiotic cell cycleGO:005144510.029
positive regulation of signalingGO:0023056560.028
formation of primary germ layerGO:0001704620.028
negative regulation of gastrulationGO:2000542110.028
neuron developmentGO:00486662620.028
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.027
leukocyte proliferationGO:007066110.027
muscle cell differentiationGO:00426921390.027
cell fate specificationGO:0001708680.027
cellular component assembly involved in morphogenesisGO:00109271070.027
oxoacid metabolic processGO:0043436310.026
organic acid metabolic processGO:0006082310.026
sensory system developmentGO:0048880760.026
intracellular signal transductionGO:0035556850.026
cellular amide metabolic processGO:004360340.026
pharyngeal system developmentGO:0060037180.026
muscle cell developmentGO:00550011150.026
bmp signaling pathwayGO:0030509520.025
otic vesicle formationGO:0030916270.025
hepaticobiliary system developmentGO:0061008980.025
positive regulation of cellular metabolic processGO:0031325940.025
regulation of dna replicationGO:000627530.025
deathGO:00162651210.025
bone developmentGO:0060348140.025
swim bladder developmentGO:0048794190.025
positive regulation of macromolecule metabolic processGO:0010604930.025
odontogenesis of dentin containing toothGO:004247510.025
generation of neuronsGO:00486993850.025
positive regulation of metabolic processGO:00098931080.025
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.024
epithelial tube morphogenesisGO:00605621480.024
striated muscle cell developmentGO:00550021080.024
negative regulation of transcription dna templatedGO:0045892450.024
regenerationGO:0031099910.023
erk1 and erk2 cascadeGO:007037140.023
aminoglycan metabolic processGO:000602290.023
positive regulation of biological processGO:00485182530.023
cell deathGO:00082191210.023
regulation of stem cell differentiationGO:200073640.023
extracellular structure organizationGO:0043062270.023
regulation of cell fate commitmentGO:0010453220.023
development of primary female sexual characteristicsGO:004654540.022
negative regulation of kinase activityGO:003367340.022
ectodermal placode morphogenesisGO:0071697320.022
regulation of stem cell proliferationGO:007209120.022
regulation of cellular component movementGO:0051270550.022
proteoglycan metabolic processGO:0006029140.022
single organism nuclear importGO:190259330.022
regulation of cell deathGO:00109411030.022
epidermal cell fate specificationGO:000995740.022
regulation of mesoderm developmentGO:2000380110.021
optic placode formation involved in camera type eye formationGO:004661930.021
mesenchyme developmentGO:00604851270.021
immune system developmentGO:00025201910.021
eye developmentGO:00016542770.021
regulation of protein ubiquitinationGO:003139630.021
mononuclear cell proliferationGO:003294310.021
head developmentGO:00603223030.021
positive regulation of macromolecule biosynthetic processGO:0010557590.020
stem cell proliferationGO:007208940.020
mesodermal cell fate specificationGO:0007501120.020
gene expressionGO:00104672520.020
positive regulation of cellular biosynthetic processGO:0031328680.020
phosphorus metabolic processGO:00067931090.020
nucleocytoplasmic transportGO:000691340.020
regulation of cytokine productionGO:000181730.019
cardiac chamber developmentGO:0003205190.019
stem cell divisionGO:001714510.019
establishment of protein localization to organelleGO:007259440.019
regulation of wnt signaling pathwayGO:0030111530.019
auditory receptor cell fate specificationGO:004266720.019
specification of symmetryGO:00097992040.019
embryonic hemopoiesisGO:0035162530.019
positive regulation of rna metabolic processGO:0051254590.019
regulation of cell activationGO:005086510.019
embryonic camera type eye formationGO:0060900100.019
positive regulation of cell activationGO:005086710.019
single organism transportGO:00447652060.019
otic vesicle morphogenesisGO:0071600340.019
cell motilityGO:00488702440.018
mesodermal cell fate commitmentGO:0001710140.018
endocrine processGO:005088620.018
response to radiationGO:0009314510.018
ubiquitin dependent protein catabolic processGO:000651130.018
cellular component assemblyGO:00226071700.018
protein acylationGO:004354330.018
regulation of neurogenesisGO:0050767870.018
regulation of endothelial cell proliferationGO:000193610.018
ventricular cardiac muscle tissue morphogenesisGO:005501020.018
positive regulation of developmental processGO:0051094500.018
regulation of cartilage developmentGO:006103570.018
lateral line system developmentGO:0048925760.018
response to glucoseGO:000974930.018
determination of heart left right asymmetryGO:00613711170.017
cellular response to external stimulusGO:007149620.017
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.017
negative regulation of epithelial cell proliferationGO:005068010.017
regulation of nervous system developmentGO:0051960900.017
cartilage condensationGO:000150230.017
cell projection assemblyGO:0030031640.017
lymphocyte proliferationGO:004665110.017
larval developmentGO:000216420.017
cellular response to radiationGO:007147840.017
hemopoiesisGO:00300971830.017
regulation of epithelial cell proliferationGO:005067830.017
cell migrationGO:00164772370.016
regulation of biological qualityGO:00650082630.016
regulation of cell morphogenesis involved in differentiationGO:0010769380.016
nephron developmentGO:0072006310.016
negative regulation of cellular biosynthetic processGO:0031327550.016
regulation of wnt signaling pathway involved in digestive tract morphogenesisGO:200005620.016
negative regulation of developmental processGO:0051093650.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
negative regulation of protein serine threonine kinase activityGO:007190120.016
embryonic neurocranium morphogenesisGO:0048702150.016
epithelial cell differentiationGO:00308551160.016
central nervous system myelinationGO:002201020.016
optic placode formationGO:000174340.016
regulation of cytoplasmic transportGO:190364940.016
organelle assemblyGO:00709251100.015
apoptotic processGO:00069151160.015
organonitrogen compound metabolic processGO:1901564740.015
response to monosaccharideGO:003428430.015
embryonic camera type eye morphogenesisGO:0048596190.015
growthGO:00400071740.015
regulation of protein modification by small protein conjugation or removalGO:190332030.015
response to nutrientGO:000758430.015
b cell activationGO:004211320.015
regulation of transcription from rna polymerase ii promoterGO:00063571140.015
negative regulation of rna metabolic processGO:0051253480.015
cell proliferationGO:0008283800.015
camera type eye developmentGO:00430102220.015
positive regulation of notch signaling pathwayGO:004574730.015
pancreas developmentGO:0031016840.015
regulation of lipase activityGO:006019120.014
cellular protein modification processGO:00064641000.014
epithelial cell proliferation involved in liver morphogenesisGO:007257520.014
renal system developmentGO:0072001940.014
appendage morphogenesisGO:0035107560.014
regulation of programmed cell deathGO:00430671010.014
positive regulation of nucleobase containing compound metabolic processGO:0045935690.014
multicellular organismal metabolic processGO:004423620.014
eye field cell fate commitment involved in camera type eye formationGO:006089830.014
regulation of cell fate specificationGO:0042659200.014
negative regulation of embryonic developmentGO:0045992110.014
regulation of protein targetingGO:190353320.014
negative regulation of dna metabolic processGO:005105340.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.014
mesenchymal cell differentiationGO:0048762870.014
axonogenesisGO:00074091520.014
endocrine system developmentGO:0035270650.014
golgi vesicle transportGO:004819330.014
cellular amino acid metabolic processGO:000652070.013
small molecule metabolic processGO:0044281770.013
endodermal cell differentiationGO:0035987190.013
regulation of intracellular protein transportGO:003315730.013
negative regulation of stem cell differentiationGO:200073720.013
single organism organelle organizationGO:19025891990.013
convergent extensionGO:00600261180.013
retina morphogenesis in camera type eyeGO:0060042790.013
convergent extension involved in organogenesisGO:0060029100.013
endodermal digestive tract morphogenesisGO:006103120.013
positive regulation of endothelial cell migrationGO:001059520.013
positive regulation of epithelial cell migrationGO:001063420.013
regulation of multicellular organism growthGO:004001440.013
regulation of cell shapeGO:000836010.013
multi organism reproductive processGO:0044703360.013
protein modification processGO:00362111000.013
specification of axis polarityGO:006500140.013
negative regulation of multicellular organismal processGO:0051241690.013
multicellular organismal reproductive processGO:0048609350.013
positive regulation of cell communicationGO:0010647560.013
heart joggingGO:0003146400.013
negative regulation of nucleobase containing compound metabolic processGO:0045934590.012
neuromast developmentGO:0048884460.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
negative regulation of cell fate specificationGO:0009996110.012
ear morphogenesisGO:0042471640.012
cell morphogenesis involved in differentiationGO:00009041950.012
skin developmentGO:0043588540.012
somitogenesisGO:0001756870.012
digestive tract morphogenesisGO:00485462310.012
branching morphogenesis of an epithelial tubeGO:0048754150.012
cell projection morphogenesisGO:00488582440.012
otic vesicle developmentGO:0071599420.012
outflow tract morphogenesisGO:000315110.012
regulation of apoptotic processGO:0042981980.012
fat soluble vitamin metabolic processGO:000677540.012
regulation of protein localization to nucleusGO:190018020.012
brain developmentGO:00074202930.012
response to carbohydrateGO:000974330.012
regulation of cellular component organizationGO:0051128860.012
mitochondrion organizationGO:000700540.012
regulation of myotube differentiationGO:001083020.012
endochondral bone morphogenesisGO:006035080.012
cellular response to fibroblast growth factor stimulusGO:0044344220.012
glial cell migrationGO:000834730.012
cardiac atrium developmentGO:000323040.012
cellular response to growth factor stimulusGO:0071363390.011
collagen biosynthetic processGO:003296420.011
liver developmentGO:0001889960.011
cilium assemblyGO:0042384580.011
phosphate containing compound metabolic processGO:00067961080.011
female sex differentiationGO:004666040.011
negative regulation of dna replicationGO:000815620.011
muscle organ developmentGO:00075171010.011
negative regulation of macromolecule biosynthetic processGO:0010558480.011
embryonic heart tube developmentGO:00350501330.011
mesoderm developmentGO:0007498880.011
peptidyl serine modificationGO:001820920.011
regulation of production of molecular mediator of immune responseGO:000270010.011
regulation of protein catabolic processGO:004217610.011
regulation of transcription involved in cell fate commitmentGO:006085010.011
pronephros developmentGO:0048793690.011
amine metabolic processGO:000930820.011
positive regulation of cellular catabolic processGO:003133130.011
monocarboxylic acid catabolic processGO:007232930.011
carbohydrate homeostasisGO:003350010.011
negative regulation of cell differentiationGO:0045596460.011
nerve developmentGO:0021675450.011
regulation of endodermal cell differentiationGO:1903224150.011
release of sequestered calcium ion into cytosolGO:005120930.011
actin filament based processGO:0030029640.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
positive regulation of gene expressionGO:0010628710.011
response to abiotic stimulusGO:00096281220.011
glycoprotein metabolic processGO:0009100230.011
macromolecule modificationGO:00434121110.011
secondary metabolic processGO:001974830.011
positive regulation of catabolic processGO:000989640.011
catecholamine biosynthetic processGO:004242320.011
cilium morphogenesisGO:0060271850.011
olfactory placode morphogenesisGO:007169970.011
canonical wnt signaling pathwayGO:0060070480.011
positive regulation of blood circulationGO:190352420.010
regulation of cellular amine metabolic processGO:003323800.010
multicellular organism growthGO:003526440.010
anterior commissure morphogenesisGO:002196030.010
regulation of protein import into nucleusGO:004230620.010
cellular response to extracellular stimulusGO:003166820.010
female gonad developmentGO:000858540.010
cellular response to organic substanceGO:00713101050.010
multi organism processGO:00517041340.010
peptidyl lysine acetylationGO:001839420.010
endodermal cell fate determinationGO:000749320.010

LOC100000500 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.039
disease of anatomical entityDOID:700.039
bone diseaseDOID:008000100.039
musculoskeletal system diseaseDOID:1700.039
bone development diseaseDOID:008000600.031