Danio rerio

5 known processes

alp

alkaline phosphatase

(Aliases: zgc:56672,Akp2,MGC56672)

alp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of signalingGO:00230512350.460
regulation of response to stimulusGO:00485832690.398
response to external stimulusGO:00096052640.395
response to abiotic stimulusGO:00096281220.308
cellular component movementGO:00069283350.302
regulation of cell communicationGO:00106462320.298
central nervous system developmentGO:00074173870.294
regulation of neurotransmitter transportGO:005158810.266
locomotionGO:00400113130.221
signal transductionGO:00071654550.218
cell migrationGO:00164772370.201
positive regulation of biological processGO:00485182530.200
regulation of signal transductionGO:00099662250.188
cellular nitrogen compound biosynthetic processGO:00442712180.180
positive regulation of transportGO:005105020.176
larval developmentGO:000216420.175
neurotransmitter transportGO:000683620.159
embryonic organ developmentGO:00485683810.158
neuron projection guidanceGO:0097485860.155
neurotransmitter secretionGO:000726920.155
biosynthetic processGO:00090582940.145
single organism transportGO:00447652060.138
positive regulation of muscle tissue developmentGO:190186310.135
response to woundingGO:00096111160.132
axon guidanceGO:0007411860.128
establishment of localizationGO:00512342440.125
single organism metabolic processGO:00447102170.119
ion homeostasisGO:0050801410.118
taxisGO:00423301090.115
chordate embryonic developmentGO:00430092710.114
cation homeostasisGO:0055080330.113
cell surface receptor signaling pathwayGO:00071663250.109
cell proliferationGO:0008283800.108
regulation of inflammatory responseGO:005072720.108
heterocycle biosynthetic processGO:00181302150.106
protein targeting to nucleusGO:004474430.106
positive regulation of nervous system developmentGO:0051962250.104
cellular aromatic compound metabolic processGO:00067252950.102
regulation of biological qualityGO:00650082630.095
nucleobase containing compound biosynthetic processGO:00346542050.094
oxoacid metabolic processGO:0043436310.093
organic substance biosynthetic processGO:19015762890.090
small molecule metabolic processGO:0044281770.088
modification dependent protein catabolic processGO:001994130.087
programmed cell deathGO:00125011190.085
positive regulation of cellular catabolic processGO:003133130.081
angiogenesisGO:00015251580.079
cell morphogenesisGO:00009022890.078
skeletal system developmentGO:00015011810.077
Mouse
regulation of receptor activityGO:001046920.077
cellular component assemblyGO:00226071700.076
regulation of cellular macromolecule biosynthetic processGO:20001122220.075
response to drugGO:004249330.073
regulation of gene expressionGO:00104682650.073
positive regulation of muscle organ developmentGO:004863610.073
positive regulation of catabolic processGO:000989640.072
somite developmentGO:0061053960.071
eye developmentGO:00016542770.070
ubiquitin dependent protein catabolic processGO:000651130.070
chemotaxisGO:00069351040.069
response to mechanical stimulusGO:0009612240.069
head developmentGO:00603223030.065
regulation of apoptotic processGO:0042981980.065
apoptotic processGO:00069151160.062
cellular response to oxygen levelsGO:007145310.062
cellular biosynthetic processGO:00442492860.062
biological adhesionGO:0022610400.062
immune system processGO:00023762410.062
inflammatory responseGO:000695480.061
vasculature developmentGO:00019442780.061
tissue migrationGO:0090130370.061
dicarboxylic acid transportGO:000683510.060
cellular protein catabolic processGO:004425740.060
aromatic compound biosynthetic processGO:00194382170.060
negative regulation of signal transductionGO:0009968940.060
blood vessel developmentGO:00015682460.058
cellular amine metabolic processGO:004410620.058
developmental growthGO:00485891660.058
regulation of cellular ketone metabolic processGO:001056570.058
macromolecule modificationGO:00434121110.058
cellular macromolecule metabolic processGO:00442603910.058
epithelial tube morphogenesisGO:00605621480.057
blood vessel morphogenesisGO:00485142160.057
cellular amino acid metabolic processGO:000652070.057
positive regulation of cellular component biogenesisGO:004408930.057
transportGO:00068102200.056
regulation of reproductive processGO:200024140.054
regulation of ion transmembrane transporter activityGO:003241220.054
regulation of cellular component organizationGO:0051128860.054
regulation of transcription dna templatedGO:00063552130.053
cell deathGO:00082191210.053
negative regulation of cellular processGO:00485232830.053
regulation of cellular amine metabolic processGO:003323800.052
regulation of cytokine productionGO:000181730.052
cellular macromolecule biosynthetic processGO:00346452240.052
positive regulation of inflammatory responseGO:005072910.052
regulation of neurological system processGO:003164420.052
heterocycle metabolic processGO:00464832900.051
regulation of nervous system developmentGO:0051960900.051
regulation of cell differentiationGO:00455951420.050
maintenance of locationGO:005123540.050
positive regulation of striated muscle tissue developmentGO:004584410.049
deathGO:00162651210.048
regulation of multicellular organismal processGO:00512392770.048
regulation of nitrogen compound metabolic processGO:00511712510.048
negative regulation of cell deathGO:0060548600.048
neuroblast proliferationGO:000740520.047
metal ion homeostasisGO:0055065260.046
ion transportGO:00068111140.046
cellular ketone metabolic processGO:0042180110.046
lipid catabolic processGO:001604240.046
modification dependent macromolecule catabolic processGO:004363230.046
growthGO:00400071740.046
cell projection organizationGO:00300302840.045
regulation of epithelial cell proliferationGO:005067830.045
negative regulation of biological processGO:00485193040.044
single organism localizationGO:19025782250.043
anion transportGO:0006820380.043
protein importGO:001703830.043
regulation of defense responseGO:0031347140.041
positive regulation of cellular processGO:00485222010.041
cellular response to hypoxiaGO:007145610.040
regulation of neurotransmitter secretionGO:004692810.039
organic cyclic compound biosynthetic processGO:19013622230.039
regulation of protein ubiquitinationGO:003139630.039
leukocyte proliferationGO:007066110.039
epithelial cell proliferationGO:0050673170.038
peptidyl serine phosphorylationGO:001810510.038
positive regulation of cell proliferationGO:0008284150.038
organic cyclic compound metabolic processGO:19013603010.038
regulation of cardiac muscle tissue developmentGO:005502410.037
cell adhesionGO:0007155400.037
positive regulation of secretion by cellGO:190353210.037
localization of cellGO:00516742440.037
carboxylic acid metabolic processGO:0019752220.037
regulation of multicellular organismal developmentGO:20000262230.037
agingGO:000756820.037
organic acid metabolic processGO:0006082310.036
positive regulation of neural precursor cell proliferationGO:200017910.036
regulation of oligodendrocyte differentiationGO:004871310.036
response to organic substanceGO:00100331530.036
Mouse
segmentationGO:0035282970.035
proteolysis involved in cellular protein catabolic processGO:005160330.035
regulation of nucleobase containing compound metabolic processGO:00192192500.035
hindbrain developmentGO:0030902910.034
positive regulation of protein kinase b signalingGO:005189710.034
positive regulation of signal transductionGO:0009967560.034
neuron neuron synaptic transmissionGO:000727010.034
regulation of circadian rhythmGO:004275240.034
enzyme linked receptor protein signaling pathwayGO:00071671060.033
regulation of cell activationGO:005086510.033
proteolysisGO:0006508380.033
mononuclear cell proliferationGO:003294310.033
regulation of peptidyl tyrosine phosphorylationGO:005073010.033
camera type eye developmentGO:00430102220.033
regulation of neural precursor cell proliferationGO:200017730.033
cellular nitrogen compound metabolic processGO:00346412900.033
neuromuscular synaptic transmissionGO:000727420.032
regulation of metabolic processGO:00192223590.032
peptidyl serine modificationGO:001820920.032
cell substrate adhesionGO:003158940.032
regulation of wnt signaling pathwayGO:0030111530.032
negative regulation of defense responseGO:003134820.032
organelle assemblyGO:00709251100.032
photoperiodismGO:0009648110.031
neuron projection morphogenesisGO:00488121610.031
positive regulation of cell cycleGO:004578730.031
amino acid transportGO:000686520.031
cellular response to decreased oxygen levelsGO:003629410.031
protein metabolic processGO:00195381830.031
axonogenesisGO:00074091520.030
positive regulation of cell communicationGO:0010647560.030
ameboidal type cell migrationGO:00016671430.029
positive regulation of developmental processGO:0051094500.029
protein modification processGO:00362111000.029
regulation of cell migrationGO:0030334400.029
cell morphogenesis involved in neuron differentiationGO:00486671630.028
protein localization to nucleusGO:003450430.028
embryo development ending in birth or egg hatchingGO:00097922710.028
connective tissue developmentGO:0061448990.028
bone developmentGO:0060348140.028
Mouse
anterior posterior pattern specificationGO:00099521520.028
positive regulation of cell adhesionGO:004578510.027
lipid storageGO:001991510.027
astrocyte differentiationGO:004870810.027
multicellular organismal response to stressGO:003355520.026
cellular component biogenesisGO:00440851780.026
lymphocyte proliferationGO:004665110.026
phosphate containing compound metabolic processGO:00067961080.026
Mouse
nitrogen compound metabolic processGO:00068073190.026
regulation of cell proliferationGO:0042127370.026
organophosphate biosynthetic processGO:0090407230.025
proteasomal protein catabolic processGO:001049820.025
skeletal system morphogenesisGO:00487051020.025
Mouse
nuclear importGO:005117030.025
regulation of rna biosynthetic processGO:20011412130.025
purine ribonucleoside monophosphate catabolic processGO:000916940.025
nucleic acid templated transcriptionGO:00976591810.025
rna metabolic processGO:00160702190.025
regulation of primary metabolic processGO:00800903110.025
regionalizationGO:00030022740.025
regulation of behaviorGO:0050795240.025
amine metabolic processGO:000930820.024
cognitionGO:005089010.024
positive regulation of epithelial cell proliferationGO:005067910.024
sensory organ developmentGO:00074233930.024
eye morphogenesisGO:00485921440.024
nucleic acid metabolic processGO:00903042440.024
macromolecule biosynthetic processGO:00090592270.024
cell fate commitmentGO:0045165990.023
positive regulation of macromolecule metabolic processGO:0010604930.023
oligodendrocyte differentiationGO:0048709230.023
cellular biogenic amine metabolic processGO:000657620.023
regulation of cellular protein catabolic processGO:190336210.023
spermatid developmentGO:000728620.023
epithelial cell morphogenesisGO:000338220.023
nucleocytoplasmic transportGO:000691340.023
regulation of biosynthetic processGO:00098892500.023
extracellular matrix assemblyGO:008502910.022
regulation of dna templated transcription in response to stressGO:004362000.022
peptidyl threonine phosphorylationGO:001810710.022
ossificationGO:0001503230.022
Mouse
regulation of glial cell differentiationGO:004568540.022
protein complex disassemblyGO:004324110.022
single organismal cell cell adhesionGO:0016337290.022
regulation of cellular amino acid metabolic processGO:000652100.022
transmembrane transportGO:00550851200.022
muscle tissue developmentGO:00605371100.022
circadian sleep wake cycle processGO:002241020.022
neural precursor cell proliferationGO:0061351200.022
segment polarity determinationGO:000736710.021
cellular protein modification processGO:00064641000.021
negative regulation of cell communicationGO:0010648960.021
peptidyl amino acid modificationGO:0018193160.021
rna biosynthetic processGO:00327741810.021
nucleoside monophosphate catabolic processGO:000912540.021
regulation of endothelial cell proliferationGO:000193610.021
locomotor rhythmGO:004547530.020
transcription dna templatedGO:00063511810.020
actin filament based processGO:0030029640.020
regulation of macromolecule biosynthetic processGO:00105562250.020
negative regulation of protein phosphorylationGO:000193340.020
cation transportGO:0006812810.020
oocyte maturationGO:000155640.020
signal transduction in absence of ligandGO:003803410.020
cellular carbohydrate metabolic processGO:004426240.020
axon extensionGO:0048675450.020
g1 s transition of mitotic cell cycleGO:000008210.020
intracellular signal transductionGO:0035556850.020
cellular component disassemblyGO:002241110.020
negative regulation of programmed cell deathGO:0043069580.020
response to oxygen levelsGO:0070482250.020
negative regulation of response to stimulusGO:00485851040.019
positive regulation of gliogenesisGO:001401520.019
regulation of programmed cell deathGO:00430671010.019
gene expressionGO:00104672520.019
positive regulation of secretionGO:005104710.019
regulation of protein catabolic processGO:004217610.019
cell growthGO:0016049570.019
cellular component morphogenesisGO:00329893360.019
positive regulation of cytokine productionGO:000181920.019
alcohol biosynthetic processGO:004616520.019
regulation of catalytic activityGO:0050790550.019
organonitrogen compound metabolic processGO:1901564740.019
regulation of cell motilityGO:2000145460.018
glycerophospholipid biosynthetic processGO:004647410.018
cell projection morphogenesisGO:00488582440.018
reactive nitrogen species metabolic processGO:200105700.018
regulation of phospholipase c activityGO:190027410.018
negative regulation of signalingGO:0023057960.018
peptidyl tyrosine phosphorylationGO:001810850.018
regulation of protein transportGO:005122330.018
catabolic processGO:0009056320.018
response to uvGO:000941130.018
transcription from rna polymerase ii promoterGO:0006366800.018
regulation of neurogenesisGO:0050767870.018
intramembranous ossificationGO:000195730.018
cellular protein metabolic processGO:00442671290.018
ion transmembrane transportGO:0034220910.017
purine nucleoside monophosphate catabolic processGO:000912840.017
ribonucleoside monophosphate catabolic processGO:000915840.017
regulation of purine nucleotide catabolic processGO:003312120.017
positive regulation of cell activationGO:005086710.017
regulation of molecular functionGO:0065009700.017
axon developmentGO:00615641660.017
sensory perception of painGO:001923310.017
lipid oxidationGO:003444010.017
negative regulation of histone modificationGO:003105710.017
odontogenesis of dentin containing toothGO:004247510.017
neuron projection developmentGO:00311751800.017
regulation of response to external stimulusGO:0032101310.017
regulation of nucleocytoplasmic transportGO:004682220.016
regulation of wound healingGO:006104120.016
negative regulation of cellular metabolic processGO:0031324770.016
protein phosphorylationGO:0006468470.016
developmental process involved in reproductionGO:0003006270.016
Mouse
response to organic cyclic compoundGO:0014070510.016
Mouse
extracellular structure organizationGO:0043062270.016
skeletal muscle organ developmentGO:0060538780.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
epithelium migrationGO:0090132250.016
peptide transportGO:001583310.016
membrane invaginationGO:001032410.016
positive regulation of multicellular organismal processGO:0051240520.016
developmental maturationGO:0021700340.016
regulation of macromolecule metabolic processGO:00602553170.016
regulation of establishment of protein localizationGO:007020140.016
positive regulation of map kinase activityGO:004340630.016
cell maturationGO:0048469230.016
regulation of nucleoside metabolic processGO:000911820.016
nucleobase containing compound metabolic processGO:00061392740.016
erk1 and erk2 cascadeGO:007037140.015
cell part morphogenesisGO:00329902460.015
axis specificationGO:0009798430.015
neuron projection extensionGO:1990138450.015
regulation of localizationGO:00328791040.015
response to endogenous stimulusGO:0009719830.015
macromolecular complex disassemblyGO:003298410.015
regulation of hormone secretionGO:004688320.015
positive regulation of response to stimulusGO:0048584800.015
response to light stimulusGO:0009416460.015
embryonic skeletal joint developmentGO:007249830.015
glycerolipid biosynthetic processGO:004501710.015
cellular monovalent inorganic cation homeostasisGO:003000420.015
regulation of nucleotide catabolic processGO:003081120.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
cellular response to chemical stimulusGO:00708871570.015
Mouse
regulation of cell developmentGO:00602841000.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.015
xanthophore differentiationGO:005093630.014
regulation of transmembrane transporter activityGO:002289820.014
regulation of calcium ion transportGO:005192420.014
establishment of synaptic vesicle localizationGO:009748010.014
cellular component assembly involved in morphogenesisGO:00109271070.014
protein polymerizationGO:005125840.014
determination of heart left right asymmetryGO:00613711170.014
generation of neuronsGO:00486993850.014
reactive oxygen species biosynthetic processGO:190340910.014
oocyte developmentGO:0048599140.014
positive regulation of transcription dna templatedGO:0045893570.014
regulation of cell deathGO:00109411030.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
tube morphogenesisGO:00352393490.014
regulation of mitotic cell cycleGO:0007346250.014
sequestering of metal ionGO:005123830.014
regulation of rna metabolic processGO:00512522240.014
protein localizationGO:0008104400.014
embryonic organ morphogenesisGO:00485622740.014
regulation of carbohydrate metabolic processGO:000610940.014
detection of external stimulusGO:0009581240.014
response to decreased oxygen levelsGO:0036293250.014
somitogenesisGO:0001756870.014
negative regulation of reproductive processGO:200024230.014
negative regulation of apoptotic processGO:0043066550.014
regulation of cellular carbohydrate metabolic processGO:001067540.013
neurological system processGO:0050877620.013
positive regulation of cell substrate adhesionGO:001081110.013
regulation of sequestering of calcium ionGO:005128240.013
positive regulation of cellular amine metabolic processGO:003324000.013
regulation of erk1 and erk2 cascadeGO:007037240.013
regulation of skeletal muscle tissue developmentGO:004864140.013
response to hypoxiaGO:0001666250.013
synaptic vesicle transportGO:004848910.013
negative regulation of kinase activityGO:003367340.013
tissue remodelingGO:004877140.013
sequestering of calcium ionGO:005120830.013
cellular response to extracellular stimulusGO:003166820.013
regulation of cellular component movementGO:0051270550.013
cellular response to external stimulusGO:007149620.013
liver developmentGO:0001889960.013
positive regulation of stem cell proliferationGO:200064810.013
negative regulation of nucleic acid templated transcriptionGO:1903507450.013
regulation of cellular biosynthetic processGO:00313262450.013
phagocytosisGO:000690930.013
neural crest cell differentiationGO:0014033720.013
carbohydrate derivative metabolic processGO:1901135610.012
regulation of cellular metabolic processGO:00313233200.012
neuron developmentGO:00486662620.012
entrainment of circadian clock by photoperiodGO:004315310.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
regulation of synaptic plasticityGO:004816710.012
regulation of metal ion transportGO:001095940.012
protein import into nucleusGO:000660630.012
response to nutrientGO:000758430.012
regulation of striated muscle tissue developmentGO:001620260.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
cell matrix adhesionGO:000716040.012
circadian sleep wake cycleGO:004274520.012
cellular lipid metabolic processGO:0044255360.012
protein secretionGO:000930610.012
alcohol metabolic processGO:0006066110.012
regulation of response to woundingGO:1903034110.012
cellular response to light stimulusGO:007148240.012
fin morphogenesisGO:0033334530.012
striated muscle cell differentiationGO:00511461290.012
chemical homeostasisGO:0048878490.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
negative regulation of epithelial cell proliferationGO:005068010.012
positive regulation of glial cell differentiationGO:004568710.012
regulation of mesenchymal cell proliferationGO:001046410.012
macromolecular complex subunit organizationGO:0043933740.012
regulation of myotube differentiationGO:001083020.012
multicellular organism growthGO:003526440.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
regulation of gtp catabolic processGO:003312420.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
regulation of locomotionGO:0040012550.012
positive regulation of signalingGO:0023056560.012
regulation of transportGO:0051049450.012
cgmp metabolic processGO:004606870.012
divalent inorganic cation homeostasisGO:0072507220.012
morphogenesis of an epitheliumGO:00020093330.012
negative regulation of rna metabolic processGO:0051253480.012
metal ion transportGO:0030001580.012
bone remodelingGO:004684920.012
cell motilityGO:00488702440.011
cellular response to toxic substanceGO:009723710.011
negative regulation of cellular catabolic processGO:003133030.011
regulation of neuron differentiationGO:0045664560.011
stem cell maintenanceGO:001982740.011
homeostatic processGO:00425921420.011
regulation of cell migration involved in sprouting angiogenesisGO:009004930.011
positive regulation of cell differentiationGO:0045597300.011
response to alkaloidGO:004327920.011
organophosphate metabolic processGO:0019637370.011
positive regulation of phospholipase c activityGO:001086310.011
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.011
periodic partitioningGO:000736510.011
heart developmentGO:00075073130.011
negative regulation of protein complex assemblyGO:003133310.011
single organism biosynthetic processGO:0044711710.011
guanosine containing compound metabolic processGO:190106840.011
positive regulation of gene expressionGO:0010628710.011
rna stabilizationGO:004348940.011
regulation of protein complex assemblyGO:004325430.011
i kappab kinase nf kappab signalingGO:000724940.011
synaptic transmissionGO:0007268350.011
response to chemicalGO:00422213200.011
Mouse
apoptotic signaling pathwayGO:0097190230.011
regulation of histone h3 k9 methylationGO:005157020.011
detection of abiotic stimulusGO:0009582240.011
multicellular organismal metabolic processGO:004423620.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
regulation of axonogenesisGO:0050770320.011
negative regulation of biosynthetic processGO:0009890550.011
cellular localizationGO:0051641970.011
regulation of transcription from rna polymerase iii promoterGO:000635910.011
regulation of cytoplasmic transportGO:190364940.011
reproductionGO:0000003400.011
notch signaling pathwayGO:0007219350.011
phagocytosis engulfmentGO:000691110.011
mesenchymal cell proliferationGO:001046310.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.011
cell cycle g1 s phase transitionGO:004484310.010
negative regulation of muscle cell differentiationGO:005114810.010
glucocorticoid biosynthetic processGO:000670410.010
transmission of nerve impulseGO:0019226190.010
b cell activationGO:004211320.010
organic substance transportGO:0071702580.010
response to monosaccharideGO:003428430.010
regulation of cell cycleGO:0051726520.010
ribose phosphate metabolic processGO:0019693270.010
smooth muscle contractionGO:000693920.010
circadian sleep wake cycle sleepGO:005080210.010
positive regulation of purine nucleotide catabolic processGO:003312310.010
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.010
negative regulation of protein kinase activityGO:000646940.010
regulation of membrane potentialGO:0042391230.010
regulation of developmental processGO:00507932470.010
response to stressGO:00069502630.010
wound healingGO:0042060900.010
adult behaviorGO:003053420.010
regulation of intracellular signal transductionGO:1902531570.010
extracellular matrix organizationGO:0030198270.010
negative regulation of cellular biosynthetic processGO:0031327550.010
regulation of heart growthGO:006042020.010

alp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.059
nervous system diseaseDOID:86300.030
brain diseaseDOID:93600.030
central nervous system diseaseDOID:33100.030
musculoskeletal system diseaseDOID:1700.027
cardiovascular system diseaseDOID:128700.017
disease of metabolismDOID:001466700.010