Danio rerio

0 known processes

appl1

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

appl1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell morphogenesisGO:00009022890.289
heart morphogenesisGO:00030071560.282
signal transductionGO:00071654550.270
tube morphogenesisGO:00352393490.218
neural tube patterningGO:0021532330.214
gastrulationGO:00073692080.208
epithelial cell developmentGO:0002064420.194
stem cell divisionGO:001714510.193
cell part morphogenesisGO:00329902460.185
cell projection morphogenesisGO:00488582440.184
cell morphogenesis involved in neuron differentiationGO:00486671630.178
cilium assemblyGO:0042384580.177
blood vessel developmentGO:00015682460.176
sensory organ developmentGO:00074233930.172
vasculature developmentGO:00019442780.164
cellular biosynthetic processGO:00442492860.160
morphogenesis of an epitheliumGO:00020093330.157
regulation of protein complex assemblyGO:004325430.152
taxisGO:00423301090.152
neuron projection morphogenesisGO:00488121610.150
cellular component morphogenesisGO:00329893360.148
generation of neuronsGO:00486993850.147
cilium organizationGO:0044782710.147
organic cyclic compound metabolic processGO:19013603010.146
cell motilityGO:00488702440.144
embryonic heart tube developmentGO:00350501330.144
cellular aromatic compound metabolic processGO:00067252950.142
determination of left right symmetryGO:00073681790.140
neuroblast proliferationGO:000740520.140
regulation of cell shapeGO:000836010.138
microtubule based movementGO:0007018330.137
cell morphogenesis involved in differentiationGO:00009041950.136
regulation of protein localization to nucleusGO:190018020.134
specification of symmetryGO:00097992040.130
cilium morphogenesisGO:0060271850.130
cell projection assemblyGO:0030031640.127
positive regulation of exocytosisGO:004592110.126
localization of cellGO:00516742440.123
actin polymerization or depolymerizationGO:000815420.123
brain developmentGO:00074202930.122
regulation of wound healingGO:006104120.117
cortical actin cytoskeleton organizationGO:003086610.116
positive regulation of muscle cell differentiationGO:005114910.116
cell projection organizationGO:00300302840.114
stem cell proliferationGO:007208940.113
nucleic acid metabolic processGO:00903042440.113
biosynthetic processGO:00090582940.111
sensory perception of touchGO:005097520.111
negative regulation of biological processGO:00485193040.109
regulation of nitrogen compound metabolic processGO:00511712510.108
phagocytosisGO:000690930.106
regulation of protein transportGO:005122330.106
larval developmentGO:000216420.105
neuron differentiationGO:00301823530.105
heart loopingGO:0001947940.105
sensory organ morphogenesisGO:00905962000.101
cytokinesisGO:000091030.101
establishment of cell polarityGO:0030010180.098
determination of bilateral symmetryGO:00098552040.097
cellular component biogenesisGO:00440851780.097
cellular component movementGO:00069283350.096
embryonic organ developmentGO:00485683810.095
establishment of mitotic spindle orientationGO:0000132100.094
establishment of localizationGO:00512342440.093
cellular nitrogen compound metabolic processGO:00346412900.092
positive regulation of transportGO:005105020.091
digestive tract morphogenesisGO:00485462310.090
regulation of macromolecule biosynthetic processGO:00105562250.087
microtubule based processGO:0007017600.087
mechanoreceptor differentiationGO:0042490370.086
organelle organizationGO:00069962270.086
heart developmentGO:00075073130.085
positive regulation of secretion by cellGO:190353210.083
auditory receptor cell fate commitmentGO:000991240.083
cell migrationGO:00164772370.082
eye developmentGO:00016542770.082
neuron developmentGO:00486662620.081
spindle assemblyGO:005122520.081
regulation of establishment of protein localizationGO:007020140.081
regulation of neural precursor cell proliferationGO:200017730.080
striated muscle cell differentiationGO:00511461290.080
blood vessel morphogenesisGO:00485142160.079
embryonic organ morphogenesisGO:00485622740.078
embryonic heart tube morphogenesisGO:00031431080.077
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.076
cortical cytoskeleton organizationGO:003086510.076
single organism nuclear importGO:190259330.076
embryonic limb morphogenesisGO:003032620.075
skin developmentGO:0043588540.074
neuron projection developmentGO:00311751800.074
cell fate commitmentGO:0045165990.073
angiogenesisGO:00015251580.073
nucleobase containing compound metabolic processGO:00061392740.073
regulation of multicellular organismal processGO:00512392770.072
negative regulation of cellular processGO:00485232830.070
positive regulation of secretionGO:005104710.069
regulation of biosynthetic processGO:00098892500.068
axon developmentGO:00615641660.068
regulation of primary metabolic processGO:00800903110.067
regulation of synapse assemblyGO:005196330.066
spindle assembly involved in mitosisGO:009030710.065
exocytosisGO:000688710.065
proteolysis involved in cellular protein catabolic processGO:005160330.065
actin filament polymerizationGO:003004120.064
protein localization to nucleusGO:003450430.064
cellular nitrogen compound biosynthetic processGO:00442712180.063
regulation of gene expressionGO:00104682650.063
regulation of exocytosisGO:001715710.062
cytoskeleton organizationGO:0007010960.062
positive regulation of wound healingGO:009030310.062
neutrophil mediated immunityGO:000244610.061
regulation of cytoplasmic transportGO:190364940.061
muscle fiber developmentGO:0048747520.061
regulation of protein polymerizationGO:003227120.060
regulation of cellular biosynthetic processGO:00313262450.060
peptidyl serine phosphorylationGO:001810510.060
neuron fate determinationGO:004866420.059
regulation of carbohydrate metabolic processGO:000610940.059
organelle localizationGO:0051640490.057
regulation of cellular metabolic processGO:00313233200.057
positive regulation of cell cycleGO:004578730.057
carboxylic acid metabolic processGO:0019752220.057
nucleocytoplasmic transportGO:000691340.057
cell migration involved in gastrulationGO:0042074790.056
nitrogen compound metabolic processGO:00068073190.056
ameboidal type cell migrationGO:00016671430.056
rho protein signal transductionGO:000726650.056
cellular localizationGO:0051641970.055
somatic stem cell maintenanceGO:003501910.055
gene expressionGO:00104672520.055
nucleic acid templated transcriptionGO:00976591810.054
inner ear receptor cell fate commitmentGO:006012040.054
regulation of cell projection assemblyGO:006049140.054
pronephros developmentGO:0048793690.053
regulation of dna replicationGO:000627530.053
regulation of signalingGO:00230512350.053
cognitionGO:005089010.052
epithelial cell morphogenesisGO:000338220.051
cellular response to radiationGO:007147840.051
heterocycle metabolic processGO:00464832900.051
membrane fusionGO:006102520.051
rna metabolic processGO:00160702190.051
endothelial cell migrationGO:0043542190.051
carbohydrate derivative metabolic processGO:1901135610.051
rna biosynthetic processGO:00327741810.050
chemotaxisGO:00069351040.050
cellular macromolecule biosynthetic processGO:00346452240.050
regulation of cell communicationGO:00106462320.050
regulation of developmental processGO:00507932470.050
regulation of protein import into nucleusGO:004230620.049
regulation of filopodium assemblyGO:005148920.049
establishment of localization in cellGO:0051649770.048
cell surface receptor signaling pathwayGO:00071663250.048
cellular component assemblyGO:00226071700.048
inner ear developmentGO:00488391260.048
regulation of synapse organizationGO:005080730.048
nuclear importGO:005117030.047
meiotic cell cycle processGO:190304630.047
regulation of stem cell proliferationGO:007209120.047
phosphatidylinositol 3 kinase signalingGO:001406520.047
maintenance of locationGO:005123540.046
positive regulation of striated muscle tissue developmentGO:004584410.046
actin filament organizationGO:0007015150.045
regulation of signal transductionGO:00099662250.045
startle responseGO:000196440.045
neuroblast differentiationGO:001401610.045
nuclear transportGO:005116940.045
establishment of protein localization to organelleGO:007259440.044
negative regulation of ras protein signal transductionGO:004658010.044
hair cell differentiationGO:0035315320.044
regulation of cardiac muscle tissue developmentGO:005502410.044
striated muscle tissue developmentGO:00147061100.044
regulation of multicellular organismal developmentGO:20000262230.044
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.044
organic substance biosynthetic processGO:19015762890.044
protein importGO:001703830.043
somite developmentGO:0061053960.043
auditory receptor cell differentiationGO:0042491150.043
positive regulation of cellular component biogenesisGO:004408930.043
regulation of multicellular organism growthGO:004001440.043
cellular amine metabolic processGO:004410620.043
regulation of blood coagulationGO:003019310.043
aorta developmentGO:003590440.043
regulation of cellular extravasationGO:000269110.042
muscle tissue developmentGO:00605371100.042
single organism organelle organizationGO:19025891990.042
protein targeting to nucleusGO:004474430.042
epithelial tube morphogenesisGO:00605621480.042
chordate embryonic developmentGO:00430092710.042
regulation of intracellular protein transportGO:003315730.042
neural tube developmentGO:0021915620.041
aromatic compound biosynthetic processGO:00194382170.041
regulation of nucleocytoplasmic transportGO:004682220.041
lateral inhibitionGO:004633110.041
erk1 and erk2 cascadeGO:007037140.040
gtp catabolic processGO:000618420.040
regulation of rna metabolic processGO:00512522240.040
protein import into nucleusGO:000660630.040
ear developmentGO:00435831270.039
regulation of response to stimulusGO:00485832690.039
organic cyclic compound biosynthetic processGO:19013622230.039
single organism biosynthetic processGO:0044711710.039
keratinocyte differentiationGO:003021600.038
protein secretionGO:000930610.038
digestive system developmentGO:00551232890.038
regulation of nucleic acid templated transcriptionGO:19035062130.038
glial cell migrationGO:000834730.037
regulation of cellular amine metabolic processGO:003323800.037
guanosine containing compound catabolic processGO:190106920.037
regulation of transcription dna templatedGO:00063552130.037
leukocyte homeostasisGO:000177620.036
immune system processGO:00023762410.036
regulation of protein targetingGO:190353320.036
spindle localizationGO:0051653120.036
positive regulation of cellular component movementGO:0051272110.036
regulation of circadian rhythmGO:004275240.035
camera type eye developmentGO:00430102220.035
single organism localizationGO:19025782250.035
regulation of metabolic processGO:00192223590.035
synaptic growth at neuromuscular junctionGO:005112420.035
stem cell maintenanceGO:001982740.035
purine nucleoside monophosphate catabolic processGO:000912840.034
detection of external stimulusGO:0009581240.034
regulation of canonical wnt signaling pathwayGO:0060828340.034
ubiquitin dependent protein catabolic processGO:000651130.034
macromolecule biosynthetic processGO:00090592270.034
chemosensory behaviorGO:000763510.034
oxoacid metabolic processGO:0043436310.034
negative regulation of protein transportGO:005122430.033
cell cycle g1 s phase transitionGO:004484310.033
hemopoiesisGO:00300971830.033
segment polarity determinationGO:000736710.033
regulation of cellular macromolecule biosynthetic processGO:20001122220.033
regulation of synaptic growth at neuromuscular junctionGO:000858210.033
digestive tract developmentGO:00485652650.032
trabecula morphogenesisGO:006138320.032
carbohydrate derivative biosynthetic processGO:1901137430.032
cellular macromolecule metabolic processGO:00442603910.032
cellular extravasationGO:004512310.032
retina development in camera type eyeGO:00600411460.031
positive regulation of striated muscle cell differentiationGO:005115510.031
glycoprotein biosynthetic processGO:0009101210.031
centrosome cycleGO:000709810.031
g1 s transition of mitotic cell cycleGO:000008210.031
enzyme linked receptor protein signaling pathwayGO:00071671060.031
pigment granule localizationGO:0051875250.031
organic acid metabolic processGO:0006082310.030
cation transportGO:0006812810.030
regulation of stem cell differentiationGO:200073640.030
heterocycle biosynthetic processGO:00181302150.030
axon guidanceGO:0007411860.030
regulation of cellular carbohydrate metabolic processGO:001067540.030
gtp metabolic processGO:004603940.030
response to external stimulusGO:00096052640.030
organonitrogen compound metabolic processGO:1901564740.029
regulation of nucleobase containing compound metabolic processGO:00192192500.029
epidermal cell differentiationGO:0009913360.029
neurological system processGO:0050877620.029
protein metabolic processGO:00195381830.029
guanosine containing compound metabolic processGO:190106840.029
single fertilizationGO:000733830.029
positive regulation of epithelial cell proliferationGO:005067910.029
establishment of spindle orientationGO:0051294100.029
locomotionGO:00400113130.028
modification dependent macromolecule catabolic processGO:004363230.028
regulation of rho protein signal transductionGO:003502320.028
regulation of organ growthGO:004662030.028
adrenal gland developmentGO:0030325100.028
mitotic nuclear divisionGO:0007067180.028
regulation of developmental growthGO:0048638380.028
neuron projection guidanceGO:0097485860.028
ion homeostasisGO:0050801410.028
regulation of cellular protein catabolic processGO:190336210.028
myeloid leukocyte mediated immunityGO:000244410.027
regulation of macromolecule metabolic processGO:00602553170.027
epidermis developmentGO:0008544480.027
muscle structure developmentGO:00610611960.027
regulation of cellular amino acid metabolic processGO:000652100.027
small molecule metabolic processGO:0044281770.027
neutrophil extravasationGO:007267210.027
sensory perception of mechanical stimulusGO:0050954160.026
axonogenesisGO:00074091520.026
chemical homeostasisGO:0048878490.026
regulation of cellular component sizeGO:0032535300.026
stem cell fate commitmentGO:004886510.026
somatic muscle developmentGO:000752540.026
transcription from rna polymerase ii promoterGO:0006366800.026
renal system developmentGO:0072001940.026
positive regulation of dna metabolic processGO:005105410.026
establishment of endothelial barrierGO:006102830.026
multicellular organism growthGO:003526440.025
b cell activationGO:004211320.025
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.025
cardiac muscle tissue developmentGO:0048738480.025
neuron neuron synaptic transmissionGO:000727010.025
myoblast fusionGO:0007520100.025
epithelial cell differentiationGO:00308551160.025
female meiotic divisionGO:000714320.025
small molecule catabolic processGO:004428230.025
amine metabolic processGO:000930820.024
compound eye developmentGO:004874920.024
cellular amino acid metabolic processGO:000652070.024
i kappab kinase nf kappab signalingGO:000724940.024
regulation of protein kinase b signalingGO:005189680.024
melanosome transportGO:0032402190.024
microtubule cytoskeleton organization involved in mitosisGO:190285010.024
single organism transportGO:00447652060.024
cellular ketone metabolic processGO:0042180110.024
cellular macromolecular complex assemblyGO:0034622240.024
proteasomal protein catabolic processGO:001049820.024
granulocyte migrationGO:0097530110.024
regulation of cell projection organizationGO:0031344440.024
spindle assembly involved in meiosisGO:009030610.024
negative regulation of mapk cascadeGO:004340940.023
positive regulation of cellular extravasationGO:000269310.023
positive regulation of multicellular organismal processGO:0051240520.023
mesenchymal cell developmentGO:0014031780.023
actin cytoskeleton organizationGO:0030036630.023
negative regulation of synapse assemblyGO:005196420.023
posterior lateral line neuromast developmentGO:0048919200.023
glycoprotein metabolic processGO:0009100230.023
regulation of anatomical structure morphogenesisGO:00226031300.023
response to woundingGO:00096111160.023
establishment or maintenance of cell polarityGO:0007163290.023
meiotic chromosome segregationGO:004513230.022
meiotic nuclear divisionGO:000712640.022
negative regulation of cell communicationGO:0010648960.022
regulation of establishment of planar polarityGO:009017540.022
regulation of cell developmentGO:00602841000.022
regulation of leukocyte mediated immunityGO:000270310.022
determination of heart left right asymmetryGO:00613711170.022
regulation of localizationGO:00328791040.022
nuclear migrationGO:000709730.022
macromolecular complex subunit organizationGO:0043933740.022
response to glucoseGO:000974930.022
primary neural tube formationGO:001402010.022
establishment of organelle localizationGO:0051656450.022
regulation of embryonic developmentGO:0045995470.021
astrocyte differentiationGO:004870810.021
small gtpase mediated signal transductionGO:000726480.021
otolith developmentGO:0048840320.021
regulation of cell motilityGO:2000145460.021
regulation of actin filament based processGO:003297090.021
regulation of neutrophil extravasationGO:200038910.021
regulation of wnt signaling pathwayGO:0030111530.021
mitotic cell cycleGO:0000278640.021
eye morphogenesisGO:00485921440.021
regulation of biological qualityGO:00650082630.021
actin filament based processGO:0030029640.021
regulation of hemostasisGO:190004610.021
nucleobase containing compound biosynthetic processGO:00346542050.020
embryonic digestive tract morphogenesisGO:004855730.020
negative regulation of protein kinase b signalingGO:005189820.020
positive regulation of cell fate commitmentGO:001045510.020
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.020
positive regulation of map kinase activityGO:004340630.020
response to hexoseGO:000974630.020
modification dependent protein catabolic processGO:001994130.020
positive regulation of protein kinase b signalingGO:005189710.020
secondary metabolic processGO:001974830.020
fertilizationGO:000956630.020
convergent extension involved in gastrulationGO:0060027710.020
regulation of neurogenesisGO:0050767870.020
epidermal cell fate specificationGO:000995740.020
cytoskeleton dependent cytokinesisGO:006164030.020
epithelial cell migrationGO:0010631250.020
cardiac cell fate commitmentGO:006091110.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.020
negative regulation of cell deathGO:0060548600.020
regulation of muscle contractionGO:000693730.020
epithelium migrationGO:0090132250.020
regulation of erk1 and erk2 cascadeGO:007037240.020
head developmentGO:00603223030.020
metal ion transportGO:0030001580.020
regulation of cellular component movementGO:0051270550.019
positive regulation of neutrophil extravasationGO:200039110.019
negative regulation of response to stimulusGO:00485851040.019
transportGO:00068102200.019
spermatid developmentGO:000728620.019
regulation of cytokine productionGO:000181730.019
macromolecular complex disassemblyGO:003298410.019
b cell mediated immunityGO:001972430.019
nucleoside monophosphate catabolic processGO:000912540.019
positive regulation of leukocyte migrationGO:000268720.019
protein polymerizationGO:005125840.019
meiosis iGO:000712710.019
agingGO:000756820.019
neuron recognitionGO:0008038180.019
canonical wnt signaling pathwayGO:0060070480.019
single organism metabolic processGO:00447102170.019
actin filament based movementGO:003004810.019
wound healingGO:0042060900.019
cellular lipid metabolic processGO:0044255360.019
isoprenoid biosynthetic processGO:000829970.018
organelle fusionGO:004828430.018
negative regulation of signal transductionGO:0009968940.018
deathGO:00162651210.018
inner ear receptor cell differentiationGO:0060113290.018
transcription dna templatedGO:00063511810.018
regulation of glial cell differentiationGO:004568540.018
ribonucleoside monophosphate catabolic processGO:000915840.018
melanin metabolic processGO:000658220.018
positive regulation of cytoskeleton organizationGO:005149530.018
endocardial cushion formationGO:000327220.018
dicarboxylic acid transportGO:000683510.018
exocrine system developmentGO:0035272280.018
positive regulation of protein complex assemblyGO:003133420.018
developmental growthGO:00485891660.018
forebrain regionalizationGO:002187140.018
phosphatidylinositol mediated signalingGO:004801520.018
ras protein signal transductionGO:000726570.018
system processGO:00030081850.017
epithelial to mesenchymal transitionGO:0001837210.017
cardiac muscle cell fate commitmentGO:006092310.017
dorsal aorta developmentGO:003590740.017
developmental cell growthGO:0048588520.017
positive regulation of cell killingGO:003134320.017
convergent extensionGO:00600261180.017
muscle cell differentiationGO:00426921390.017
optic placode formation involved in camera type eye formationGO:004661930.017
regulation of cellular ketone metabolic processGO:001056570.017
outflow tract morphogenesisGO:000315110.017
positive regulation of cellular amine metabolic processGO:003324000.017
regulation of bmp signaling pathwayGO:0030510390.017
modification of morphology or physiology of other organismGO:003582140.017
periodic partitioningGO:000736510.017
inositol lipid mediated signalingGO:004801720.017
stem cell fate determinationGO:004886710.017
positive regulation of cellular catabolic processGO:003133130.017
endothelial cell fate commitmentGO:006083930.016
spermatid differentiationGO:004851520.016
i kappab phosphorylationGO:000725210.016
response to chemicalGO:00422213200.016
regulation of establishment or maintenance of cell polarityGO:003287820.016
negative regulation of signalingGO:0023057960.016
dendrite morphogenesisGO:004881350.016
sensory perceptionGO:0007600390.016
proximal distal pattern formationGO:000995410.016
establishment of mitotic spindle localizationGO:0040001120.016
stem cell differentiationGO:00488631170.016
diencephalon developmentGO:0021536580.016
neuroblast fate commitmentGO:001401710.016
segmentationGO:0035282970.016
regulation of protein depolymerizationGO:190187910.016
epithelial cell morphogenesis involved in gastrulationGO:000338110.016
aorta morphogenesisGO:003590930.016
kupffer s vesicle developmentGO:0070121500.016
phagocytosis engulfmentGO:000691110.016
glomerular epithelium developmentGO:0072010120.016
endocardium morphogenesisGO:000316040.016
regulation of transcription from rna polymerase ii promoterGO:00063571140.016
mesoderm morphogenesisGO:0048332510.016
establishment of pigment granule localizationGO:0051905220.016
immune effector processGO:0002252230.016
embryo development ending in birth or egg hatchingGO:00097922710.016
protein localization to plasma membraneGO:007265910.016
endocrine processGO:005088620.016
regulation of metal ion transportGO:001095940.016
phosphorus metabolic processGO:00067931090.016
regulation of neutrophil migrationGO:190262260.015
positive regulation of cell projection organizationGO:003134690.015
positive regulation of cytokine productionGO:000181920.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
negative regulation of protein phosphorylationGO:000193340.015
polarized epithelial cell differentiationGO:003085940.015
regulation of chromosome segregationGO:005198310.015
myeloid leukocyte migrationGO:0097529120.015
cellular pigmentationGO:0033059300.015
regulation of cell activationGO:005086510.015
cell activationGO:0001775160.015
response to drugGO:004249330.015
b cell differentiationGO:003018310.015
multi organism processGO:00517041340.015
response to stressGO:00069502630.015
regulation of endocrine processGO:004406020.015
atp catabolic processGO:000620040.015
regulation of heart growthGO:006042020.015
response to other organismGO:0051707970.015
positive regulation of biological processGO:00485182530.015
response to uvGO:000941130.015
cellular protein catabolic processGO:004425740.015
wnt signaling pathwayGO:0016055800.015
central nervous system developmentGO:00074173870.015
hematopoietic or lymphoid organ developmentGO:00485341910.015
regulation of neurological system processGO:003164420.015
leukocyte proliferationGO:007066110.015
tissue migrationGO:0090130370.015
brain morphogenesisGO:0048854180.015
negative regulation of jnk cascadeGO:004632910.015
regulation of rna biosynthetic processGO:20011412130.015
segment specificationGO:0007379120.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.015
single organism membrane fusionGO:004480120.015

appl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
muscular diseaseDOID:008000000.022
musculoskeletal system diseaseDOID:1700.022
myopathyDOID:42300.018
muscle tissue diseaseDOID:6600.018
disease of metabolismDOID:001466700.017