Danio rerio

79 known processes

atp1a2a

ATPase, Na+/K+ transporting, alpha 2a polypeptide

(Aliases: cb702,atpa2,wu:fa10d05,atp1a2,atp[a]2,fa10d05,fa10d04)

atp1a2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
skeletal muscle tissue developmentGO:0007519670.710
muscle structure developmentGO:00610611960.684
larval developmentGO:000216420.675
Worm
single organism transportGO:00447652060.668
skeletal muscle organ developmentGO:0060538780.620
actomyosin structure organizationGO:0031032530.505
chordate embryonic developmentGO:00430092710.499
Zebrafish
anterior posterior pattern specificationGO:00099521520.493
Zebrafish
single organism localizationGO:19025782250.479
heart developmentGO:00075073130.478
regulation of nucleic acid templated transcriptionGO:19035062130.452
ion transmembrane transportGO:0034220910.427
Zebrafish Mouse Rat Worm Fly
organic cyclic compound biosynthetic processGO:19013622230.414
regulation of nitrogen compound metabolic processGO:00511712510.389
developmental growthGO:00485891660.376
Fly
somite developmentGO:0061053960.364
specification of axis polarityGO:006500140.348
monovalent inorganic cation transportGO:0015672420.346
Zebrafish Mouse Rat Worm Fly
regulation of cellular metabolic processGO:00313233200.341
specification of symmetryGO:00097992040.338
cellular biosynthetic processGO:00442492860.330
embryonic heart tube developmentGO:00350501330.319
specification of organ axis polarityGO:001008420.313
somitogenesisGO:0001756870.303
cellular nitrogen compound metabolic processGO:00346412900.298
Zebrafish Mouse Rat Worm Fly
myofibril assemblyGO:0030239480.296
biosynthetic processGO:00090582940.282
regionalizationGO:00030022740.279
Zebrafish
single organism organelle organizationGO:19025891990.272
muscle cell differentiationGO:00426921390.271
adult behaviorGO:003053420.249
Mouse Fly
morphogenesis of an epitheliumGO:00020093330.241
establishment of localizationGO:00512342440.241
gene expressionGO:00104672520.238
rna biosynthetic processGO:00327741810.228
metal ion transportGO:0030001580.225
Zebrafish Mouse Rat Worm Fly
actin filament based processGO:0030029640.223
Rat
transportGO:00068102200.219
myotube differentiationGO:0014902450.210
regulation of cellular macromolecule biosynthetic processGO:20001122220.207
macromolecule biosynthetic processGO:00090592270.192
cellular component assemblyGO:00226071700.188
Fly
regulation of rna biosynthetic processGO:20011412130.188
negative regulation of heart contractionGO:004582220.181
Mouse
striated muscle cell developmentGO:00550021080.179
determination of bilateral symmetryGO:00098552040.179
nucleic acid templated transcriptionGO:00976591810.178
maintenance of locationGO:005123540.167
taxisGO:00423301090.165
striated muscle cell differentiationGO:00511461290.160
regulation of macromolecule biosynthetic processGO:00105562250.158
cation transportGO:0006812810.157
Zebrafish Mouse Rat Worm Fly
agingGO:000756820.157
Fly
regulation of metabolic processGO:00192223590.156
ion transportGO:00068111140.154
Zebrafish Mouse Rat Worm Fly
potassium ion transmembrane transportGO:0071805100.152
Zebrafish Mouse Rat Worm Fly
striated muscle tissue developmentGO:00147061100.150
potassium ion transportGO:0006813100.143
Zebrafish Mouse Rat Worm Fly
determination of heart left right asymmetryGO:00613711170.141
hepatocyte proliferationGO:007257420.138
regulation of transcription dna templatedGO:00063552130.137
cation transmembrane transportGO:0098655650.135
Zebrafish Mouse Rat Worm Fly
semicircular canal developmentGO:0060872240.134
Zebrafish
lipid storageGO:001991510.133
segmentationGO:0035282970.128
transcription dna templatedGO:00063511810.128
aromatic compound biosynthetic processGO:00194382170.122
cellular component biogenesisGO:00440851780.120
Fly
muscle organ developmentGO:00075171010.118
growthGO:00400071740.117
Worm Fly
regulation of cellular biosynthetic processGO:00313262450.113
nucleoside monophosphate catabolic processGO:000912540.111
Zebrafish Mouse Rat Worm Fly
muscle tissue developmentGO:00605371100.109
positive regulation of biological processGO:00485182530.108
sensory organ developmentGO:00074233930.108
Zebrafish
cellular aromatic compound metabolic processGO:00067252950.106
Zebrafish Mouse Rat Worm Fly
small molecule metabolic processGO:0044281770.105
Zebrafish Mouse Rat Worm Fly
rna metabolic processGO:00160702190.105
regulation of biological qualityGO:00650082630.101
regulation of metal ion transportGO:001095940.101
Rat
epithelial tube morphogenesisGO:00605621480.099
mesoderm morphogenesisGO:0048332510.098
organelle organizationGO:00069962270.097
membrane repolarizationGO:008600920.095
protein metabolic processGO:00195381830.093
Worm
connective tissue developmentGO:0061448990.090
blood circulationGO:0008015870.087
tissue regenerationGO:0042246740.087
cell migrationGO:00164772370.086
Zebrafish
otolith developmentGO:0048840320.082
Zebrafish
inorganic cation transmembrane transportGO:0098662500.082
Zebrafish Mouse Rat Worm Fly
cell projection organizationGO:00300302840.081
stem cell proliferationGO:007208940.081
locomotionGO:00400113130.080
renal tubule morphogenesisGO:006133310.079
heart morphogenesisGO:00030071560.079
regulation of blood circulationGO:1903522320.079
Mouse Rat
nucleobase containing compound biosynthetic processGO:00346542050.079
response to abiotic stimulusGO:00096281220.078
Mouse Rat Fly
nitrogen compound metabolic processGO:00068073190.078
Zebrafish Mouse Rat Worm Fly
myotube cell developmentGO:0014904350.077
heterocycle biosynthetic processGO:00181302150.077
organic acid metabolic processGO:0006082310.075
mitochondrion organizationGO:000700540.075
skeletal muscle fiber developmentGO:0048741350.075
pharyngeal muscle developmentGO:004328240.075
regulation of biosynthetic processGO:00098892500.074
cell morphogenesisGO:00009022890.072
Fly
regulation of multicellular organismal processGO:00512392770.072
Mouse Rat Worm
regulation of transcription from rna polymerase ii promoterGO:00063571140.072
oxoacid metabolic processGO:0043436310.071
regulation of signalingGO:00230512350.071
anatomical structure homeostasisGO:0060249360.069
Fly
positive regulation of transportGO:005105020.066
positive regulation of rna metabolic processGO:0051254590.066
modification dependent protein catabolic processGO:001994130.064
inorganic ion transmembrane transportGO:0098660570.064
Zebrafish Mouse Rat Worm Fly
regulation of primary metabolic processGO:00800903110.062
purine ribonucleoside monophosphate catabolic processGO:000916940.061
Zebrafish Mouse Rat Worm Fly
epithelial cell proliferation involved in liver morphogenesisGO:007257520.061
epithalamus developmentGO:0021538100.060
cellular component movementGO:00069283350.059
Zebrafish Mouse Rat
regulation of system processGO:0044057400.059
Mouse Rat Worm
cation homeostasisGO:0055080330.058
modification dependent macromolecule catabolic processGO:004363230.057
regulation of stem cell proliferationGO:007209120.057
mitotic cell cycle processGO:1903047480.057
skeletal system developmentGO:00015011810.056
organic cyclic compound metabolic processGO:19013603010.055
Zebrafish Mouse Rat Worm Fly
determination of left right symmetryGO:00073681790.055
cell matrix adhesionGO:000716040.053
regulation of transportGO:0051049450.052
Rat
apical junction assemblyGO:004329710.052
Fly
cell motilityGO:00488702440.052
Zebrafish Mouse Rat
positive regulation of catabolic processGO:000989640.050
transmembrane transportGO:00550851200.050
Zebrafish Mouse Rat Worm Fly
muscle cell developmentGO:00550011150.050
positive regulation of cellular component biogenesisGO:004408930.049
tube morphogenesisGO:00352393490.049
heterocycle metabolic processGO:00464832900.049
Zebrafish Mouse Rat Worm Fly
organic substance biosynthetic processGO:19015762890.048
positive regulation of cellular processGO:00485222010.047
organic substance catabolic processGO:1901575280.047
Zebrafish Mouse Rat Worm Fly
sodium ion transmembrane transportGO:0035725210.047
Zebrafish Mouse Rat Worm Fly
protein targeting to nucleusGO:004474430.047
single organism behaviorGO:0044708240.045
Mouse Fly
nucleoside metabolic processGO:0009116110.044
Zebrafish Mouse Rat Worm Fly
cell surface receptor signaling pathwayGO:00071663250.044
embryonic organ developmentGO:00485683810.043
organonitrogen compound metabolic processGO:1901564740.043
Zebrafish Mouse Rat Worm Fly
organelle assemblyGO:00709251100.043
central nervous system developmentGO:00074173870.043
Zebrafish
purine ribonucleotide metabolic processGO:0009150270.042
Zebrafish Mouse Rat Worm Fly
positive regulation of cellular catabolic processGO:003133130.042
positive regulation of nucleobase containing compound metabolic processGO:0045935690.041
actin cytoskeleton organizationGO:0030036630.041
purine nucleoside monophosphate catabolic processGO:000912840.040
Zebrafish Mouse Rat Worm Fly
limb bud formationGO:006017420.039
forebrain developmentGO:0030900960.039
meiotic nuclear divisionGO:000712640.038
macromolecular complex subunit organizationGO:0043933740.037
eye field cell fate commitment involved in camera type eye formationGO:006089830.037
morphogenesis of an epithelial foldGO:006057110.037
establishment of protein localization to organelleGO:007259440.037
negative regulation of blood circulationGO:190352320.036
Mouse
programmed cell deathGO:00125011190.036
optic placode formationGO:000174340.036
regulation of localizationGO:00328791040.036
Rat
homeostatic processGO:00425921420.036
regulation of rna metabolic processGO:00512522240.035
mesoderm developmentGO:0007498880.035
sensory perceptionGO:0007600390.035
Fly
fatty acid oxidationGO:001939510.035
system processGO:00030081850.035
response to stressGO:00069502630.035
membrane hyperpolarizationGO:006008110.034
cilium morphogenesisGO:0060271850.034
single organism metabolic processGO:00447102170.034
Zebrafish Mouse Rat Worm Fly
localization of cellGO:00516742440.034
Zebrafish Mouse Rat
nucleobase containing compound metabolic processGO:00061392740.033
Zebrafish Mouse Rat Worm Fly
regulation of cell matrix adhesionGO:000195210.033
embryonic skeletal system developmentGO:0048706970.033
intracellular signal transductionGO:0035556850.033
cartilage developmentGO:0051216960.032
proteolysis involved in cellular protein catabolic processGO:005160330.032
cardiocyte differentiationGO:0035051440.032
Zebrafish
regulation of gene expressionGO:00104682650.032
positive regulation of nucleic acid templated transcriptionGO:1903508570.032
cellular component assembly involved in morphogenesisGO:00109271070.032
catabolic processGO:0009056320.031
Zebrafish Mouse Rat Worm Fly
cellular localizationGO:0051641970.031
carboxylic acid metabolic processGO:0019752220.030
cell substrate adhesionGO:003158940.030
response to external stimulusGO:00096052640.030
regulation of nucleobase containing compound metabolic processGO:00192192500.030
cellular response to external stimulusGO:007149620.029
Rat
positive regulation of nucleotide catabolic processGO:003081310.029
notochord developmentGO:0030903540.029
cellular nitrogen compound biosynthetic processGO:00442712180.028
nucleic acid metabolic processGO:00903042440.028
positive regulation of cellular metabolic processGO:0031325940.028
embryonic eye morphogenesisGO:0048048300.028
negative regulation of anterior neural cell fate commitment of the neural plateGO:002200110.028
regulation of neural precursor cell proliferationGO:200017730.028
embryonic heart tube morphogenesisGO:00031431080.028
cardiac atrium developmentGO:000323040.028
eye developmentGO:00016542770.028
cellular amine metabolic processGO:004410620.027
voluntary skeletal muscle contractionGO:000301040.027
signal transductionGO:00071654550.027
negative regulation of cellular metabolic processGO:0031324770.027
actin mediated cell contractionGO:007025210.027
Rat
regulation of actin filament based processGO:003297090.027
Rat
protein complex subunit organizationGO:0071822460.026
heart loopingGO:0001947940.026
multicellular organism growthGO:003526440.025
regulation of programmed cell deathGO:00430671010.025
vestibular receptor cell differentiationGO:006011430.025
myoblast fusionGO:0007520100.025
epithelial cell fate commitmentGO:0072148110.025
muscle fiber developmentGO:0048747520.025
sensory system developmentGO:0048880760.025
synaptic growth at neuromuscular junctionGO:005112420.025
Fly
glutamate receptor signaling pathwayGO:000721510.025
cellular sodium ion homeostasisGO:000688310.025
somatic muscle developmentGO:000752540.025
response to oxygen containing compoundGO:1901700550.025
Mouse Rat
endocardial cushion formationGO:000327220.025
positive regulation of macromolecule metabolic processGO:0010604930.024
embryo development ending in birth or egg hatchingGO:00097922710.024
Zebrafish Worm Fly
negative regulation of cellular processGO:00485232830.024
Rat
transcription from rna polymerase ii promoterGO:0006366800.024
muscle system processGO:0003012200.023
Mouse Rat Worm
protein localization to nucleusGO:003450430.023
positive regulation of metabolic processGO:00098931080.023
regenerationGO:0031099910.023
regulation of signal transductionGO:00099662250.022
regulation of sodium ion transportGO:000202820.022
Rat
central nervous system neuron differentiationGO:0021953740.022
kupffer s vesicle developmentGO:0070121500.022
metal ion homeostasisGO:0055065260.022
single organism nuclear importGO:190259330.022
protein oligomerizationGO:005125970.022
regulation of cell substrate adhesionGO:001081010.021
tissue remodelingGO:004877140.021
lipid oxidationGO:003444010.021
regulation of skeletal muscle tissue developmentGO:004864140.021
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.021
rhombomere 5 developmentGO:002157140.021
peripheral nervous system neuron differentiationGO:0048934280.021
midbrain hindbrain boundary developmentGO:0030917230.021
Zebrafish
cellular response to organic substanceGO:00713101050.021
Mouse Rat
wound healingGO:0042060900.020
head developmentGO:00603223030.020
Zebrafish
bmp signaling pathwayGO:0030509520.020
regulation of cell communicationGO:00106462320.020
cellular amino acid metabolic processGO:000652070.020
regulation of nucleocytoplasmic transportGO:004682220.020
hepatic duct developmentGO:006101120.020
protein complex assemblyGO:0006461300.020
autophagyGO:000691440.020
regulation of meiotic cell cycleGO:005144510.020
diencephalon developmentGO:0021536580.019
positive regulation of transcription dna templatedGO:0045893570.019
regulation of transporter activityGO:003240920.019
Rat
protein import into nucleusGO:000660630.019
rostrocaudal neural tube patterningGO:0021903290.019
Zebrafish
regulation of nucleoside metabolic processGO:000911820.019
nuclear divisionGO:0000280230.019
proteasomal protein catabolic processGO:001049820.019
response to growth factorGO:0070848390.019
regulation of nucleotide catabolic processGO:003081120.018
macromolecular complex assemblyGO:0065003350.018
multicellular organismal homeostasisGO:0048871290.018
Fly
cell migration involved in heart developmentGO:0060973220.018
Zebrafish
apoptotic processGO:00069151160.018
regulation of cellular component movementGO:0051270550.018
Rat
cytoskeleton organizationGO:0007010960.018
habenula developmentGO:002198690.018
positive regulation of biosynthetic processGO:0009891680.017
ubiquitin dependent protein catabolic processGO:000651130.017
cell projection assemblyGO:0030031640.017
nuclear importGO:005117030.017
positive regulation of mesenchymal cell proliferationGO:000205310.017
mediolateral intercalationGO:006003130.017
positive regulation of cellular biosynthetic processGO:0031328680.017
digestive tract morphogenesisGO:00485462310.017
protein homooligomerizationGO:005126030.017
positive regulation of purine nucleotide catabolic processGO:003312310.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
negative regulation of dna metabolic processGO:005105340.017
cell cycle arrestGO:000705010.017
embryonic camera type eye formationGO:0060900100.016
mesoderm formationGO:0001707430.016
glucocorticoid biosynthetic processGO:000670410.016
chemical homeostasisGO:0048878490.016
action potentialGO:0001508190.016
Worm
regulation of cellular amine metabolic processGO:003323800.016
positive regulation of cell adhesionGO:004578510.016
cellular protein catabolic processGO:004425740.015
response to carbohydrateGO:000974330.015
regulation of response to cytokine stimulusGO:006075930.015
heart formationGO:0060914130.015
positive regulation of skeletal muscle tissue developmentGO:004864310.015
tissue homeostasisGO:0001894250.015
Fly
ion homeostasisGO:0050801410.015
protein modification processGO:00362111000.015
negative regulation of biological processGO:00485193040.015
Mouse Rat
regulation of myotube differentiationGO:001083020.015
cell part morphogenesisGO:00329902460.015
nuclear transportGO:005116940.015
sensory perception of mechanical stimulusGO:0050954160.015
Fly
pharyngeal system developmentGO:0060037180.015
regulation of multicellular organism growthGO:004001440.015
regulation of membrane potentialGO:0042391230.015
Mouse Worm
cell substrate junction assemblyGO:000704420.015
sodium ion transportGO:0006814240.015
Zebrafish Mouse Rat Worm Fly
peptidyl serine modificationGO:001820920.015
cellular macromolecule biosynthetic processGO:00346452240.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
positive regulation of cell activationGO:005086710.014
endocardial cushion morphogenesisGO:000320330.014
endothelial cell fate commitmentGO:006083930.014
nucleocytoplasmic transportGO:000691340.014
regulation of reproductive processGO:200024140.014
regulation of epithelial cell proliferationGO:005067830.014
macromolecule localizationGO:0033036540.014
regulation of cell proliferationGO:0042127370.014
mitotic cell cycleGO:0000278640.014
positive regulation of rna biosynthetic processGO:1902680570.014
regulation of purine nucleotide catabolic processGO:003312120.014
cardiac atrium morphogenesisGO:000320920.013
positive regulation of macromolecule biosynthetic processGO:0010557590.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
organic acid catabolic processGO:001605430.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.013
cellular component morphogenesisGO:00329893360.013
Fly
neurological system processGO:0050877620.013
Mouse Fly
thrombocyte differentiationGO:000257440.013
negative regulation of macromolecule metabolic processGO:0010605760.013
cellular ketone metabolic processGO:0042180110.013
organelle fissionGO:0048285230.013
regulation of cell shapeGO:000836010.013
Fly
digestive system developmentGO:00551232890.012
regulation of insulin like growth factor receptor signaling pathwayGO:004356710.012
regulation of autophagyGO:001050630.012
positive regulation of cytoskeleton organizationGO:005149530.012
pronephros developmentGO:0048793690.012
liver developmentGO:0001889960.012
protein importGO:001703830.012
negative regulation of dna replicationGO:000815620.012
phosphorylationGO:0016310690.012
nephron epithelium morphogenesisGO:007208810.012
olfactory bulb developmentGO:002177240.012
positive regulation of muscle organ developmentGO:004863610.012
synaptic transmissionGO:0007268350.012
Mouse Fly
negative regulation of signalingGO:0023057960.012
embryonic pattern specificationGO:0009880440.012
dorsal ventral pattern formationGO:00099531250.011
ossificationGO:0001503230.011
embryonic neurocranium morphogenesisGO:0048702150.011
growth plate cartilage developmentGO:000341720.011
apoptotic process involved in developmentGO:190274220.011
carboxylic acid catabolic processGO:004639530.011
response to temperature stimulusGO:0009266150.011
Fly
extracellular structure organizationGO:0043062270.011
Zebrafish
negative regulation of muscle tissue developmentGO:190186220.011
behaviorGO:0007610740.011
Zebrafish Mouse Fly
semicircular canal morphogenesisGO:0048752180.011
Zebrafish
response to organic cyclic compoundGO:0014070510.011
Mouse Rat
hormone biosynthetic processGO:004244630.011
cellular calcium ion homeostasisGO:0006874130.011
nucleobase containing compound catabolic processGO:0034655150.011
Zebrafish Mouse Rat Worm Fly
cell deathGO:00082191210.011
cellular response to starvationGO:000926710.011
embryonic skeletal system morphogenesisGO:0048704930.011
negative regulation of multicellular organismal processGO:0051241690.011
Mouse
endochondral bone growthGO:000341620.011
fatty acid beta oxidationGO:000663510.011
ribonucleoside monophosphate catabolic processGO:000915840.011
Zebrafish Mouse Rat Worm Fly
regulation of ion transmembrane transporter activityGO:003241220.011
Rat
generation of neuronsGO:00486993850.011
cellular response to organic cyclic compoundGO:0071407380.011
Mouse Rat
ear developmentGO:00435831270.011
Zebrafish
protein catabolic processGO:003016370.011
Worm
regulation of mesenchymal cell proliferationGO:001046410.011
phosphorus metabolic processGO:00067931090.011
Zebrafish Mouse Rat Worm Fly
amine metabolic processGO:000930820.011
peptidyl serine phosphorylationGO:001810510.011
cellular macromolecule metabolic processGO:00442603910.010
regulation of dna templated transcription elongationGO:003278430.010
negative regulation of cellular biosynthetic processGO:0031327550.010
negative regulation of mitosisGO:004583930.010
regulation of locomotionGO:0040012550.010
negative regulation of mapk cascadeGO:004340940.010
regulation of cell proliferation involved in heart morphogenesisGO:200013620.010
nephron tubule morphogenesisGO:007207810.010

atp1a2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.090
musculoskeletal system diseaseDOID:1700.045
muscle tissue diseaseDOID:6600.031
myopathyDOID:42300.031
muscular diseaseDOID:008000000.031
nervous system diseaseDOID:86300.024
heart diseaseDOID:11400.019
cardiomyopathyDOID:005070000.019
cardiovascular system diseaseDOID:128700.019
intrinsic cardiomyopathyDOID:006003600.011
charcot marie tooth disease type 2DOID:005053900.011
neuropathyDOID:87000.011
neuromuscular diseaseDOID:44000.011
charcot marie tooth diseaseDOID:1059500.011