Danio rerio

0 known processes

atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

(Aliases: wu:fb26e12,wu:fb52h08,MGC66223,wu:fb94e07,zgc:66223,atrxl)

atrx biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.524
mitotic dna integrity checkpointGO:004477440.359
regulation of primary metabolic processGO:00800903110.196
regulation of metabolic processGO:00192223590.195
cellular component movementGO:00069283350.193
immune system processGO:00023762410.166
agingGO:000756820.163
immune system developmentGO:00025201910.162
cellular macromolecule metabolic processGO:00442603910.162
embryo development ending in birth or egg hatchingGO:00097922710.159
negative regulation of cellular processGO:00485232830.155
nuclear migrationGO:000709730.154
fertilizationGO:000956630.152
localization of cellGO:00516742440.149
mitotic g2 m transition checkpointGO:004481830.144
negative regulation of ras protein signal transductionGO:004658010.140
hematopoietic or lymphoid organ developmentGO:00485341910.138
locomotionGO:00400113130.136
organic cyclic compound metabolic processGO:19013603010.128
regulation of gene expressionGO:00104682650.125
single organism reproductive processGO:0044702400.119
regulation of multicellular organismal developmentGO:20000262230.109
neuron developmentGO:00486662620.104
positive regulation of biological processGO:00485182530.102
negative regulation of biological processGO:00485193040.100
hemopoiesisGO:00300971830.094
cytokinesisGO:000091030.091
cell migrationGO:00164772370.088
multicellular organism reproductionGO:0032504350.086
heterocycle metabolic processGO:00464832900.082
intracellular estrogen receptor signaling pathwayGO:003052030.080
regulation of macromolecule metabolic processGO:00602553170.080
positive regulation of myeloid cell differentiationGO:004563920.080
multicellular organism growthGO:003526440.078
reproductive processGO:0022414400.077
cellular component biogenesisGO:00440851780.077
cell motilityGO:00488702440.077
spindle assemblyGO:005122520.077
single organism organelle organizationGO:19025891990.076
gene expressionGO:00104672520.076
organelle organizationGO:00069962270.076
gastrulationGO:00073692080.074
mitotic dna damage checkpointGO:004477340.072
nucleobase containing compound metabolic processGO:00061392740.072
response to stressGO:00069502630.070
single fertilizationGO:000733830.070
nitrogen compound metabolic processGO:00068073190.070
ubiquitin dependent protein catabolic processGO:000651130.068
cellular component disassemblyGO:002241110.067
heterocycle biosynthetic processGO:00181302150.066
mitotic cell cycleGO:0000278640.066
axon developmentGO:00615641660.066
protein metabolic processGO:00195381830.066
meiotic nuclear divisionGO:000712640.065
mrna metabolic processGO:0016071200.064
regulation of rna metabolic processGO:00512522240.061
regulation of biological qualityGO:00650082630.061
negative regulation of nitrogen compound metabolic processGO:0051172590.060
homeostasis of number of cellsGO:0048872620.060
regulation of cell shapeGO:000836010.058
positive regulation of transcription dna templatedGO:0045893570.058
g2 dna damage checkpointGO:003157230.057
negative regulation of tor signalingGO:003200720.056
autophagyGO:000691440.055
positive regulation of macromolecule metabolic processGO:0010604930.054
cell cycle processGO:0022402530.054
organic substance biosynthetic processGO:19015762890.053
rna metabolic processGO:00160702190.053
nuclear transportGO:005116940.053
cellular protein metabolic processGO:00442671290.051
cellular nitrogen compound metabolic processGO:00346412900.051
mrna splicing via spliceosomeGO:0000398100.051
erythrocyte differentiationGO:0030218540.050
negative regulation of signalingGO:0023057960.050
negative regulation of mitotic cell cycleGO:0045930110.049
regulation of biosynthetic processGO:00098892500.049
mitotic g2 dna damage checkpointGO:000709530.048
cellular component morphogenesisGO:00329893360.048
regulation of apoptotic processGO:0042981980.048
maintenance of locationGO:005123540.047
cellular biosynthetic processGO:00442492860.046
regulation of cellular metabolic processGO:00313233200.045
regulation of cell developmentGO:00602841000.045
regulation of anatomical structure morphogenesisGO:00226031300.045
negative regulation of small gtpase mediated signal transductionGO:005105810.045
g2 m transition of mitotic cell cycleGO:000008640.044
deathGO:00162651210.044
hatchingGO:003518840.043
cytoskeleton organizationGO:0007010960.043
regulation of mrna processingGO:005068430.043
regulation of nitrogen compound metabolic processGO:00511712510.043
homeostatic processGO:00425921420.043
multi organism processGO:00517041340.042
growthGO:00400071740.042
cell surface receptor signaling pathwayGO:00071663250.041
regulation of response to stimulusGO:00485832690.041
developmental maturationGO:0021700340.040
regulation of chromosome segregationGO:005198310.039
negative regulation of rna metabolic processGO:0051253480.039
regulation of cell cycleGO:0051726520.039
melanin metabolic processGO:000658220.038
regulation of locomotionGO:0040012550.038
cellular aromatic compound metabolic processGO:00067252950.038
cell morphogenesisGO:00009022890.037
negative regulation of gene expressionGO:0010629650.037
aromatic compound biosynthetic processGO:00194382170.037
regulation of multicellular organism growthGO:004001440.036
chromosome organizationGO:0051276310.036
establishment of localizationGO:00512342440.036
cell cycle g2 m phase transitionGO:004483940.035
cell cycleGO:0007049930.035
regulation of programmed cell deathGO:00430671010.035
protein complex disassemblyGO:004324110.035
central nervous system developmentGO:00074173870.034
response to external stimulusGO:00096052640.034
cell deathGO:00082191210.034
transportGO:00068102200.033
regulation of macromolecule biosynthetic processGO:00105562250.033
positive regulation of cellular catabolic processGO:003133130.033
positive regulation of cell cycleGO:004578730.033
generation of neuronsGO:00486993850.033
regulation of protein complex assemblyGO:004325430.033
developmental growthGO:00485891660.033
proteolysis involved in cellular protein catabolic processGO:005160330.033
nucleocytoplasmic transportGO:000691340.033
rna processingGO:0006396250.032
positive regulation of cellular processGO:00485222010.032
regulation of cellular macromolecule biosynthetic processGO:20001122220.032
regulation of cell differentiationGO:00455951420.032
protein modification processGO:00362111000.032
rna transportGO:005065820.032
myeloid cell differentiationGO:0030099860.031
establishment of localization in cellGO:0051649770.031
regulation of reproductive processGO:200024140.031
rna biosynthetic processGO:00327741810.031
regulation of nucleic acid templated transcriptionGO:19035062130.031
mitotic cell cycle phase transitionGO:004477290.031
neuron differentiationGO:00301823530.030
transcription dna templatedGO:00063511810.030
neuron remodelingGO:001632210.030
negative regulation of metabolic processGO:0009892860.030
regulation of establishment of protein localizationGO:007020140.029
cell projection organizationGO:00300302840.029
erythrocyte homeostasisGO:0034101550.029
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.029
positive regulation of programmed cell deathGO:0043068290.029
mitotic cell cycle checkpointGO:000709350.028
cellular protein catabolic processGO:004425740.028
regulation of developmental processGO:00507932470.028
digestive system developmentGO:00551232890.028
negative regulation of cell communicationGO:0010648960.028
macromolecular complex disassemblyGO:003298410.028
positive regulation of catabolic processGO:000989640.028
protein polymerizationGO:005125840.028
negative regulation of macromolecule metabolic processGO:0010605760.028
sensory organ developmentGO:00074233930.027
negative regulation of intracellular signal transductionGO:1902532220.027
apoptotic processGO:00069151160.027
nucleobase containing compound biosynthetic processGO:00346542050.027
mitotic metaphase plate congressionGO:000708010.027
regulation of cytoplasmic transportGO:190364940.027
embryonic limb morphogenesisGO:003032620.027
regulation of mrna splicing via spliceosomeGO:004802430.026
myeloid cell homeostasisGO:0002262560.026
regenerationGO:0031099910.026
negative regulation of mitotic cell cycle phase transitionGO:190199150.026
stem cell divisionGO:001714510.026
developmental process involved in reproductionGO:0003006270.026
stem cell maintenanceGO:001982740.026
cellular carbohydrate metabolic processGO:004426240.026
positive regulation of reproductive processGO:200024320.026
signal transductionGO:00071654550.025
nucleobase containing compound transportGO:001593120.025
positive regulation of dna templated transcription elongationGO:003278610.025
modification dependent macromolecule catabolic processGO:004363230.025
multi organism reproductive processGO:0044703360.025
regulation of protein ubiquitinationGO:003139630.025
proteasomal protein catabolic processGO:001049820.024
stem cell proliferationGO:007208940.024
negative regulation of cytoplasmic transportGO:190365020.024
establishment or maintenance of cell polarityGO:0007163290.024
rna export from nucleusGO:000640510.024
positive regulation of metabolic processGO:00098931080.024
defense responseGO:0006952470.024
positive regulation of cellular biosynthetic processGO:0031328680.024
sexual reproductionGO:0019953360.023
rna localizationGO:000640340.023
nucleic acid metabolic processGO:00903042440.023
nucleic acid transportGO:005065720.023
embryonic organ developmentGO:00485683810.023
multi organism cellular processGO:004476420.022
protein localization to nucleusGO:003450430.022
nuclear importGO:005117030.022
regulation of response to external stimulusGO:0032101310.022
viral processGO:001603210.022
axon extensionGO:0048675450.022
stem cell differentiationGO:00488631170.022
internal peptidyl lysine acetylationGO:001839320.022
biosynthetic processGO:00090582940.021
symbiosis encompassing mutualism through parasitismGO:004440340.021
positive regulation of transportGO:005105020.021
single organism metabolic processGO:00447102170.021
regulation of transcription dna templatedGO:00063552130.021
response to uvGO:000941130.021
regulation of nervous system developmentGO:0051960900.021
reproductionGO:0000003400.020
meiotic spindle organizationGO:000021210.020
heart developmentGO:00075073130.020
negative regulation of nucleobase containing compound metabolic processGO:0045934590.020
cell maturationGO:0048469230.020
negative regulation of cell deathGO:0060548600.020
negative regulation of axon regenerationGO:004868140.020
histone lysine demethylationGO:007007620.020
regulation of extrinsic apoptotic signaling pathwayGO:200123630.020
regulation of cell migrationGO:0030334400.020
establishment of spindle localizationGO:0051293120.020
inner ear developmentGO:00488391260.020
positive regulation of rna metabolic processGO:0051254590.020
negative regulation of programmed cell deathGO:0043069580.019
negative regulation of kinase activityGO:003367340.019
regulation of cellular protein catabolic processGO:190336210.019
protein targeting to nucleusGO:004474430.019
cellular response to external stimulusGO:007149620.019
regulation of protein localization to nucleusGO:190018020.019
muscle structure developmentGO:00610611960.019
negative regulation of neuron projection regenerationGO:007057140.019
positive regulation of cellular amine metabolic processGO:003324000.019
negative regulation of nuclear divisionGO:005178430.019
regulation of cell cycle phase transitionGO:190198780.019
lipid storageGO:001991510.019
single organism localizationGO:19025782250.019
regulation of alternative mrna splicing via spliceosomeGO:000038110.019
histone h3 k4 methylationGO:005156820.019
regulation of neurological system processGO:003164420.019
regulation of anatomical structure sizeGO:0090066330.019
dna templated transcription elongationGO:000635430.019
determination of dorsal identityGO:0048263130.019
histone h3 k9 modificationGO:006164750.019
ribonucleoprotein complex biogenesisGO:0022613130.019
negative regulation of dna metabolic processGO:005105340.018
regulation of neurogenesisGO:0050767870.018
protein importGO:001703830.018
cellular component assemblyGO:00226071700.018
secondary metabolic processGO:001974830.018
response to woundingGO:00096111160.018
regulation of protein targetingGO:190353320.018
microtubule cytoskeleton organizationGO:0000226330.018
positive regulation of multicellular organismal processGO:0051240520.018
regulation of cell activationGO:005086510.018
immune effector processGO:0002252230.018
chemosensory behaviorGO:000763510.018
protein complex subunit organizationGO:0071822460.018
positive regulation of apoptotic signaling pathwayGO:200123510.018
organic cyclic compound biosynthetic processGO:19013622230.018
regulation of cellular component movementGO:0051270550.018
oocyte differentiationGO:0009994140.018
regulation of nucleobase containing compound metabolic processGO:00192192500.017
intracellular signal transductionGO:0035556850.017
cell cycle phase transitionGO:004477090.017
oogenesisGO:0048477140.017
regulation of mitotic cell cycleGO:0007346250.017
regulation of cell deathGO:00109411030.017
internal protein amino acid acetylationGO:000647520.017
mitotic cell cycle processGO:1903047480.017
tube morphogenesisGO:00352393490.017
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.017
meiotic cell cycle processGO:190304630.017
negative regulation of rna splicingGO:003311910.017
dna catabolic processGO:000630810.017
digestive tract morphogenesisGO:00485462310.017
regulation of cell motilityGO:2000145460.017
mesenchymal cell differentiationGO:0048762870.016
establishment of mitotic spindle localizationGO:0040001120.016
negative regulation of cell cycle phase transitionGO:190198850.016
establishment of rna localizationGO:005123630.016
negative regulation of protein kinase activityGO:000646940.016
modification dependent protein catabolic processGO:001994130.016
positive regulation of cell deathGO:0010942290.016
rna stabilizationGO:004348940.016
nuclear exportGO:005116810.016
cellular response to extracellular stimulusGO:003166820.016
response to virusGO:0009615210.016
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.016
monocyte differentiationGO:003022420.016
transcription from rna polymerase ii promoterGO:0006366800.016
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.016
regulation of protein catabolic processGO:004217610.016
organism emergence from protective structureGO:007168440.016
response to other organismGO:0051707970.016
positive regulation of chromosome organizationGO:200125210.016
translational initiationGO:000641330.016
mrna transportGO:005102820.016
positive regulation of carbohydrate metabolic processGO:004591310.015
centrosome organizationGO:005129710.015
regulation of protein metabolic processGO:0051246560.015
regulation of multicellular organismal processGO:00512392770.015
cellular macromolecule biosynthetic processGO:00346452240.015
neuron projection regenerationGO:0031102160.015
negative regulation of nucleocytoplasmic transportGO:004682320.015
negative regulation of cellular metabolic processGO:0031324770.015
macromolecule modificationGO:00434121110.015
locomotor rhythmGO:004547530.015
mesoderm developmentGO:0007498880.015
regulation of mitotic cell cycle phase transitionGO:190199080.015
cell projection morphogenesisGO:00488582440.015
establishment of protein localization to organelleGO:007259440.015
negative regulation of signal transductionGO:0009968940.015
protein import into nucleusGO:000660630.015
development of primary female sexual characteristicsGO:004654540.015
segment polarity determinationGO:000736710.015
cellular response to dsrnaGO:007135910.015
regulation of cellular protein metabolic processGO:0032268520.015
dorsal ventral pattern formationGO:00099531250.015
cellular protein modification processGO:00064641000.015
positive regulation of immune system processGO:0002684170.015
regulation of localizationGO:00328791040.015
mononuclear cell proliferationGO:003294310.015
positive regulation of apoptotic processGO:0043065290.015
neuroblast proliferationGO:000740520.014
positive regulation of cell activationGO:005086710.014
pronuclear migrationGO:003504610.014
positive regulation of cellular carbohydrate metabolic processGO:001067610.014
positive regulation of biosynthetic processGO:0009891680.014
positive regulation of nucleic acid templated transcriptionGO:1903508570.014
mitotic cytokinesisGO:000028130.014
response to organic substanceGO:00100331530.014
activation of mapk activityGO:000018730.014
positive regulation of multi organism processGO:004390230.014
single organism nuclear importGO:190259330.014
polyol metabolic processGO:001975110.014
neuron projection morphogenesisGO:00488121610.014
establishment of organelle localizationGO:0051656450.014
cell proliferationGO:0008283800.014
positive regulation of chromosome segregationGO:005198410.014
protein polyubiquitinationGO:000020940.014
anterior posterior pattern specificationGO:00099521520.014
somatic muscle developmentGO:000752540.014
chromosome localizationGO:005000020.014
regulation of establishment of planar polarityGO:009017540.014
macroautophagyGO:001623610.013
pole plasm assemblyGO:000731540.013
response to superoxideGO:000030320.013
astral microtubule organizationGO:003095310.013
negative regulation of translationGO:001714810.013
regulation of cell projection organizationGO:0031344440.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.013
regulation of cell communicationGO:00106462320.013
production of molecular mediator of immune responseGO:000244020.013
cell death in response to oxidative stressGO:003647320.013
protein modification by small protein removalGO:007064610.013
protein demethylationGO:000648220.013
multicellular organismal reproductive processGO:0048609350.013
maternal determination of anterior posterior axis embryoGO:000835840.013
embryonic organ morphogenesisGO:00485622740.013
chromosome segregationGO:0007059120.013
mrna stabilizationGO:004825540.013
cognitionGO:005089010.013
mrna catabolic processGO:000640260.013
response to drugGO:004249330.013
cellular macromolecule localizationGO:0070727210.013
female gamete generationGO:0007292140.013
system processGO:00030081850.013
regulation of nucleocytoplasmic transportGO:004682220.013
wnt signaling pathwayGO:0016055800.013
germ cell developmentGO:0007281220.013
regulation of protein depolymerizationGO:190187910.013
response to oxygen radicalGO:000030520.012
spliceosomal snrnp assemblyGO:000038720.012
extrinsic apoptotic signaling pathwayGO:009719130.012
regulation of dna templated transcription elongationGO:003278430.012
positive regulation of secretionGO:005104710.012
multicellular organismal macromolecule metabolic processGO:004425920.012
cell substrate adherens junction assemblyGO:000704510.012
axon regenerationGO:0031103140.012
negative regulation of macromolecule biosynthetic processGO:0010558480.012
centrosome cycleGO:000709810.012
negative regulation of map kinase activityGO:004340720.012
programmed cell deathGO:00125011190.012
protein acetylationGO:000647320.012
protein acylationGO:004354330.012
cytoplasm organizationGO:000702840.012
single organism biosynthetic processGO:0044711710.012
membrane organizationGO:0061024210.012
sister chromatid segregationGO:000081960.012
heart contractionGO:0060047710.012
protein dealkylationGO:000821420.012
regulation of production of molecular mediator of immune responseGO:000270010.012
regulation of reactive oxygen species metabolic processGO:200037720.012
organelle fissionGO:0048285230.012
positive regulation of canonical wnt signaling pathwayGO:009026340.012
meiotic chromosome segregationGO:004513230.012
regulation of myelinationGO:003164110.012
organonitrogen compound metabolic processGO:1901564740.012
mrna 3 end processingGO:003112420.012
innate immune responseGO:0045087130.012
neuromuscular synaptic transmissionGO:000727420.012
golgi vesicle transportGO:004819330.012
head developmentGO:00603223030.012
positive regulation of macromolecule biosynthetic processGO:0010557590.012
posttranscriptional regulation of gene expressionGO:0010608140.011
macromolecule biosynthetic processGO:00090592270.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
regulation of neuron differentiationGO:0045664560.011
carbohydrate biosynthetic processGO:001605110.011
protein depolymerizationGO:005126110.011
myeloid cell developmentGO:0061515320.011
regulation of meiotic cell cycleGO:005144510.011
cellular amine metabolic processGO:004410620.011
regulation of neuron projection developmentGO:0010975400.011
dna integrity checkpointGO:003157060.011
regulation of rho protein signal transductionGO:003502320.011
neurotransmitter transportGO:000683620.011
cellular nitrogen compound biosynthetic processGO:00442712180.011
oocyte constructionGO:000730850.011
negative regulation of biosynthetic processGO:0009890550.011
protein secretionGO:000930610.011
negative regulation of intracellular transportGO:003238730.011
organelle localizationGO:0051640490.011
meiosis iGO:000712710.011
regulation of organelle assemblyGO:190211540.011
immune responseGO:0006955280.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
regulation of mitosisGO:000708890.011
interspecies interaction between organismsGO:004441940.011
macromolecular complex subunit organizationGO:0043933740.011
protein stabilizationGO:005082120.011
regulation of cellular amine metabolic processGO:003323800.011
canonical wnt signaling pathwayGO:0060070480.011
spliceosomal complex assemblyGO:000024510.011
mrna processingGO:0006397140.011
brain developmentGO:00074202930.011
negative regulation of response to stimulusGO:00485851040.011
positive regulation of cell divisionGO:005178120.011
nucleic acid templated transcriptionGO:00976591810.011
specification of organ identityGO:001009220.011
regulation of intracellular protein transportGO:003315730.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
tissue regenerationGO:0042246740.011
ribosomal small subunit biogenesisGO:004227420.011
negative regulation of multi organism processGO:004390130.011
neuron projection developmentGO:00311751800.011
cell substrate junction assemblyGO:000704420.010
peptidyl lysine trimethylationGO:001802310.010
meiosis iiGO:000713510.010
regulation of neural precursor cell proliferationGO:200017730.010
response to axon injuryGO:0048678140.010
regulation of neuron projection regenerationGO:007057070.010
single organism transportGO:00447652060.010
negative regulation of cell cycle processGO:001094890.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
epithelial cell morphogenesisGO:000338220.010
response to oxygen containing compoundGO:1901700550.010
regulation of cellular component sizeGO:0032535300.010
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.010
carboxylic acid metabolic processGO:0019752220.010
muscle system processGO:0003012200.010
positive regulation of cytoskeleton organizationGO:005149530.010
negative regulation of synapse assemblyGO:005196420.010
cellular ketone metabolic processGO:0042180110.010
regulation of cellular ketone metabolic processGO:001056570.010

atrx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.202
nervous system diseaseDOID:86300.048
motor neuron diseaseDOID:23100.034
neurodegenerative diseaseDOID:128900.034
amyotrophic lateral sclerosisDOID:33200.034
central nervous system diseaseDOID:33100.034
disease of cellular proliferationDOID:1456600.030
cancerDOID:16200.030
organ system cancerDOID:005068600.027
musculoskeletal system diseaseDOID:1700.024
thoracic cancerDOID:509300.018
myopathyDOID:42300.011
muscle tissue diseaseDOID:6600.011
muscular diseaseDOID:008000000.011