Danio rerio

22 known processes

aurkb

aurora kinase B

(Aliases: MGC85918,fa09g06,wu:fa09g06,CHUNP6896,stka)

aurkb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spindle assemblyGO:005122520.838
Yeast Worm
positive regulation of cellular processGO:00485222010.826
Yeast
regulation of meiotic cell cycleGO:005144510.799
spindle assembly involved in meiosisGO:009030610.789
regulation of chromosome segregationGO:005198310.784
cell cycleGO:0007049930.768
single organism reproductive processGO:0044702400.757
Worm
organelle organizationGO:00069962270.754
cleavage furrow formationGO:003608920.715
meiotic nuclear divisionGO:000712640.670
Yeast Worm
macromolecule biosynthetic processGO:00090592270.628
female meiotic divisionGO:000714320.627
meiosis iiGO:000713510.610
Yeast
cellular aromatic compound metabolic processGO:00067252950.597
Worm
cellular macromolecule metabolic processGO:00442603910.590
Human Yeast Worm
reproductive processGO:0022414400.563
Worm
meiosis iGO:000712710.493
Yeast
positive regulation of cell cycleGO:004578730.491
Yeast
oocyte maturationGO:000155640.479
mitotic cell cycleGO:0000278640.475
ubiquitin dependent protein catabolic processGO:000651130.474
regulation of primary metabolic processGO:00800903110.474
mitotic nuclear divisionGO:0007067180.457
Yeast Zebrafish Worm
heart developmentGO:00075073130.441
mitotic cell cycle processGO:1903047480.425
heterocycle metabolic processGO:00464832900.401
Worm
regulation of developmental processGO:00507932470.398
centrosome cycleGO:000709810.388
mitotic dna integrity checkpointGO:004477440.380
Yeast
organic substance biosynthetic processGO:19015762890.379
proteolysis involved in cellular protein catabolic processGO:005160330.377
meiotic spindle organizationGO:000021210.376
regulation of mitotic cell cycle phase transitionGO:190199080.365
Yeast
microtubule depolymerizationGO:000701910.363
sister chromatid segregationGO:000081960.360
Yeast
cell cycle processGO:0022402530.356
single organism organelle organizationGO:19025891990.354
modification dependent macromolecule catabolic processGO:004363230.345
microtubule organizing center organizationGO:003102310.344
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.334
nuclear migrationGO:000709730.331
mitotic metaphase plate congressionGO:000708010.331
heterocycle biosynthetic processGO:00181302150.324
histone phosphorylationGO:001657220.320
modification dependent protein catabolic processGO:001994130.314
regulation of protein import into nucleusGO:004230620.311
Yeast
meiotic chromosome segregationGO:004513230.308
Yeast
fertilizationGO:000956630.302
spindle assembly involved in female meiosisGO:000705610.300
nucleobase containing compound biosynthetic processGO:00346542050.290
cellular nitrogen compound metabolic processGO:00346412900.286
Worm
regulation of gene expressionGO:00104682650.280
microtubule based processGO:0007017600.276
positive regulation of chromosome segregationGO:005198410.271
pronuclear migrationGO:003504610.268
embryo development ending in birth or egg hatchingGO:00097922710.268
Worm
aromatic compound biosynthetic processGO:00194382170.267
reproductionGO:0000003400.266
Yeast Worm
cellular protein catabolic processGO:004425740.261
regulation of multicellular organismal processGO:00512392770.254
positive regulation of chromosome organizationGO:200125210.247
mitotic sister chromatid segregationGO:000007060.243
nuclear transportGO:005116940.243
Yeast
positive regulation of biological processGO:00485182530.239
Yeast
negative regulation of chromosome organizationGO:200125110.236
centrosome organizationGO:005129710.235
single fertilizationGO:000733830.234
regulation of apoptotic processGO:0042981980.229
regulation of biological qualityGO:00650082630.229
Yeast
meiotic cell cycle processGO:190304630.227
Yeast
cellular biosynthetic processGO:00442492860.225
cellular localizationGO:0051641970.224
Yeast
mitotic spindle organizationGO:000705250.223
Yeast Worm
histone modificationGO:0016570200.218
regulation of macromolecule biosynthetic processGO:00105562250.208
regulation of protein metabolic processGO:0051246560.206
regulation of transcription dna templatedGO:00063552130.206
cellular component biogenesisGO:00440851780.205
Yeast Worm
nuclear divisionGO:0000280230.201
Yeast Zebrafish Worm
multi organism reproductive processGO:0044703360.198
regulation of nucleocytoplasmic transportGO:004682220.194
Yeast
cytokinetic processGO:003250620.192
regulation of cellular metabolic processGO:00313233200.190
nitrogen compound metabolic processGO:00068073190.190
Worm
regulation of organelle organizationGO:0033043290.190
Yeast
microtubule based movementGO:0007018330.189
peptidyl serine phosphorylationGO:001810510.188
Worm
dna metabolic processGO:0006259270.185
Worm
cytoskeleton dependent cytokinesisGO:006164030.181
larval developmentGO:000216420.181
male meiosisGO:000714020.175
negative regulation of mitosisGO:004583930.170
mitotic cell cycle embryonicGO:004544820.168
proteasomal protein catabolic processGO:001049820.166
cell projection organizationGO:00300302840.166
cytoskeleton organizationGO:0007010960.163
negative regulation of cell deathGO:0060548600.161
cell cycle g2 m phase transitionGO:004483940.160
nucleic acid templated transcriptionGO:00976591810.159
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.155
biosynthetic processGO:00090582940.153
spindle assembly involved in mitosisGO:009030710.153
Yeast Worm
regulation of protein ubiquitinationGO:003139630.151
positive regulation of multicellular organismal processGO:0051240520.146
organelle localizationGO:0051640490.146
organelle fusionGO:004828430.143
astral microtubule organizationGO:003095310.142
positive regulation of metabolic processGO:00098931080.139
regulation of metabolic processGO:00192223590.136
regulation of cell cycleGO:0051726520.133
Yeast Worm
organic cyclic compound biosynthetic processGO:19013622230.133
meiotic cell cycleGO:005132150.132
Yeast Worm
organelle fissionGO:0048285230.131
Yeast Zebrafish Worm
response to stressGO:00069502630.130
regulation of nucleobase containing compound metabolic processGO:00192192500.130
macromolecule catabolic processGO:0009057150.130
multi organism processGO:00517041340.129
positive regulation of transportGO:005105020.129
regulation of rna metabolic processGO:00512522240.128
rna metabolic processGO:00160702190.127
nucleocytoplasmic transportGO:000691340.126
Yeast
mitotic cell cycle checkpointGO:000709350.123
Yeast
establishment of protein localization to organelleGO:007259440.122
Yeast
sexual reproductionGO:0019953360.122
regulation of protein catabolic processGO:004217610.121
negative regulation of catabolic processGO:000989530.121
cellular process involved in reproduction in multicellular organismGO:0022412280.119
regulation of establishment of protein localizationGO:007020140.119
Yeast
positive regulation of catabolic processGO:000989640.118
positive regulation of macromolecule metabolic processGO:0010604930.118
protein metabolic processGO:00195381830.117
Human Yeast Worm
organic cyclic compound metabolic processGO:19013603010.117
Worm
regulation of rna biosynthetic processGO:20011412130.117
regulation of reproductive processGO:200024140.116
negative regulation of cellular processGO:00485232830.115
Yeast
protein localization to nucleusGO:003450430.109
Yeast
negative regulation of protein localization to nucleusGO:190018120.108
Yeast
regulation of cellular component organizationGO:0051128860.106
Yeast
phosphorus metabolic processGO:00067931090.102
Human Yeast Worm
microtubule polymerization or depolymerizationGO:003110930.102
negative regulation of gene expressionGO:0010629650.101
protein complex subunit organizationGO:0071822460.099
Yeast Worm
developmental process involved in reproductionGO:0003006270.099
Worm
generation of neuronsGO:00486993850.098
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.097
gene expressionGO:00104672520.097
regulation of bindingGO:005109830.097
microtubule polymerizationGO:004678520.094
cell projection morphogenesisGO:00488582440.092
single organism nuclear importGO:190259330.090
Yeast
growthGO:00400071740.090
peptidyl threonine phosphorylationGO:001810710.090
Worm
establishment of localizationGO:00512342440.089
Yeast Worm
cellular nitrogen compound biosynthetic processGO:00442712180.087
response to chemicalGO:00422213200.087
regulation of heart growthGO:006042020.087
nuclear importGO:005117030.086
Yeast
centrosome duplicationGO:005129810.085
rna processingGO:0006396250.084
developmental growthGO:00485891660.082
organic substance catabolic processGO:1901575280.082
cellular protein metabolic processGO:00442671290.082
Human Yeast Worm
multicellular organismal reproductive processGO:0048609350.081
regulation of protein transportGO:005122330.080
Yeast
protein targeting to nucleusGO:004474430.080
Yeast
protein modification processGO:00362111000.080
Human Yeast Worm
cellular component assemblyGO:00226071700.079
Yeast Worm
nucleobase containing compound metabolic processGO:00061392740.078
Worm
protein destabilizationGO:003164810.077
single organism metabolic processGO:00447102170.076
Worm
regulation of macromolecule metabolic processGO:00602553170.076
neuron differentiationGO:00301823530.074
chromosome localizationGO:005000020.074
macromolecular complex subunit organizationGO:0043933740.074
Yeast Worm
nuclear envelope organizationGO:000699820.074
negative regulation of protein transportGO:005122430.074
Yeast
regulation of cellular macromolecule biosynthetic processGO:20001122220.073
negative regulation of cellular catabolic processGO:003133030.072
nucleus organizationGO:000699770.071
protein importGO:001703830.071
Yeast
embryonic cleavageGO:004001630.070
cell deathGO:00082191210.068
g2 m transition of mitotic cell cycleGO:000008640.068
multicellular organism reproductionGO:0032504350.067
microtubule cytoskeleton organization involved in mitosisGO:190285010.067
Yeast Worm
negative regulation of metabolic processGO:0009892860.067
regulation of cellular biosynthetic processGO:00313262450.067
spindle organizationGO:000705150.066
Yeast Worm
catabolic processGO:0009056320.066
regulation of intracellular protein transportGO:003315730.065
Yeast
regulation of cellular protein catabolic processGO:190336210.065
regulation of protein targetingGO:190353320.063
Yeast
regulation of protein modification by small protein conjugation or removalGO:190332030.062
female meiosis iiGO:000714710.061
negative regulation of macromolecule metabolic processGO:0010605760.060
macromolecule modificationGO:00434121110.059
Human Yeast Worm
programmed cell deathGO:00125011190.058
positive regulation of cellular catabolic processGO:003133130.058
mitotic g2 m transition checkpointGO:004481830.058
negative regulation of programmed cell deathGO:0043069580.058
germ cell developmentGO:0007281220.057
g2 dna damage checkpointGO:003157230.057
rna localizationGO:000640340.056
regulation of cell cycle processGO:0010564200.056
Yeast Worm
regulation of chromosome organizationGO:003304450.056
establishment of organelle localizationGO:0051656450.056
single organism localizationGO:19025782250.055
Yeast
male gamete generationGO:004823270.055
regulation of cellular protein metabolic processGO:0032268520.054
positive regulation of histone modificationGO:003105810.053
regulation of cell deathGO:00109411030.053
cytokinesisGO:000091030.052
maintenance of locationGO:005123540.052
Yeast
cell morphogenesisGO:00009022890.052
transportGO:00068102200.052
Yeast
leukocyte homeostasisGO:000177620.051
positive regulation of cellular metabolic processGO:0031325940.051
cellular response to dna damage stimulusGO:0006974240.051
nucleic acid metabolic processGO:00903042440.051
Worm
regulation of transportGO:0051049450.050
Yeast
protein polymerizationGO:005125840.049
cellular protein modification processGO:00064641000.048
Human Yeast Worm
digestive system developmentGO:00551232890.047
establishment of localization in cellGO:0051649770.047
Yeast
smoothened signaling pathwayGO:0007224300.047
negative regulation of intracellular protein transportGO:009031730.045
Yeast
oocyte developmentGO:0048599140.045
regulation of nitrogen compound metabolic processGO:00511712510.044
peptidyl serine modificationGO:001820920.044
Worm
cell proliferationGO:0008283800.043
regulation of multicellular organism growthGO:004001440.043
small molecule metabolic processGO:0044281770.042
karyogamyGO:000074120.042
determination of bilateral symmetryGO:00098552040.041
apoptotic processGO:00069151160.041
establishment of chromosome localizationGO:005130320.041
negative regulation of neural precursor cell proliferationGO:200017810.041
protein depolymerizationGO:005126110.040
chromosome segregationGO:0007059120.040
positive regulation of protein metabolic processGO:0051247230.040
female meiosis chromosome segregationGO:001632110.040
regulation of cellular ketone metabolic processGO:001056570.039
negative regulation of intracellular transportGO:003238730.039
Yeast
oogenesisGO:0048477140.039
chromosome organization involved in meiosisGO:007019210.039
Yeast
mitotic cytokinesisGO:000028130.038
immune system processGO:00023762410.038
negative regulation of mitotic cell cycle phase transitionGO:190199150.037
Yeast
nucleoside phosphate metabolic processGO:0006753280.037
cellular macromolecule catabolic processGO:0044265120.037
single organism transportGO:00447652060.036
Yeast
regulation of programmed cell deathGO:00430671010.036
protein polyubiquitinationGO:000020940.036
negative regulation of biological processGO:00485193040.036
Yeast
cell cycle checkpointGO:000007570.035
Yeast
negative regulation of developmental processGO:0051093650.035
female gamete generationGO:0007292140.035
macromolecular complex disassemblyGO:003298410.035
Yeast
negative regulation of cell cycle phase transitionGO:190198850.035
Yeast
gamete generationGO:0007276330.035
protein localization to microtubule cytoskeletonGO:007269810.034
dna biosynthetic processGO:007189730.034
cellular component disassemblyGO:002241110.034
Yeast
homologous chromosome segregationGO:004514310.034
Yeast
negative regulation of nucleobase containing compound metabolic processGO:0045934590.034
rna biosynthetic processGO:00327741810.034
deathGO:00162651210.033
regulation of protein localization to nucleusGO:190018020.033
Yeast
regulation of nucleic acid templated transcriptionGO:19035062130.033
regulation of proteolysisGO:0030162240.032
oocyte differentiationGO:0009994140.032
chromatin modificationGO:0016568210.031
regulation of biosynthetic processGO:00098892500.030
negative regulation of mitotic cell cycleGO:0045930110.030
Yeast
mitotic g2 dna damage checkpointGO:000709530.030
chromosome organizationGO:0051276310.029
Yeast Worm
regulation of oocyte developmentGO:006028130.029
protein complex disassemblyGO:004324110.029
Yeast
transcription dna templatedGO:00063511810.029
nucleus localizationGO:005164780.028
developmental maturationGO:0021700340.028
organonitrogen compound metabolic processGO:1901564740.028
positive regulation of oocyte developmentGO:006028210.028
negative regulation of cellular metabolic processGO:0031324770.027
cellular catabolic processGO:0044248270.027
regulation of mitotic cell cycleGO:0007346250.027
Yeast
cellular ketone metabolic processGO:0042180110.027
phosphate containing compound metabolic processGO:00067961080.027
Human Yeast Worm
reproductive structure developmentGO:004860850.026
Worm
regulation of gene expression epigeneticGO:0040029110.026
multicellular organism growthGO:003526440.026
organic acid metabolic processGO:0006082310.026
positive regulation of nitrogen compound metabolic processGO:0051173690.025
negative regulation of nucleocytoplasmic transportGO:004682320.025
Yeast
establishment of rna localizationGO:005123630.025
transcription from rna polymerase ii promoterGO:0006366800.025
negative regulation of cytoplasmic transportGO:190365020.025
Yeast
response to lipidGO:0033993600.024
mrna processingGO:0006397140.024
peptidyl threonine modificationGO:001821010.024
Worm
phosphorylationGO:0016310690.024
Human Yeast Worm
regulation of localizationGO:00328791040.024
Yeast
oxoacid metabolic processGO:0043436310.024
organic substance transportGO:0071702580.024
Yeast
digestive tract developmentGO:00485652650.024
translational initiationGO:000641330.023
cellular protein complex disassemblyGO:004362410.022
negative regulation of apoptotic processGO:0043066550.022
anterior posterior pattern specificationGO:00099521520.022
regulation of multicellular organismal developmentGO:20000262230.022
spermatid differentiationGO:004851520.022
reciprocal dna recombinationGO:003582510.021
neuron projection developmentGO:00311751800.021
negative regulation of nuclear divisionGO:005178430.021
cellular component movementGO:00069283350.021
cell death in response to oxidative stressGO:003647320.020
rna 3 end processingGO:003112320.020
spermatid developmentGO:000728620.020
stem cell maintenanceGO:001982740.020
positive regulation of chromatin modificationGO:190331010.020
regulation of cell differentiationGO:00455951420.020
regulation of cell cycle phase transitionGO:190198780.019
Yeast
response to drugGO:004249330.019
regulation of protein complex disassemblyGO:004324410.019
g1 s transition of mitotic cell cycleGO:000008210.019
protein localizationGO:0008104400.019
Yeast Worm
macromolecular complex assemblyGO:0065003350.019
Yeast Worm
mitotic dna damage checkpointGO:004477340.019
cellular macromolecule biosynthetic processGO:00346452240.019
cell maturationGO:0048469230.019
response to abiotic stimulusGO:00096281220.019
positive regulation of multi organism processGO:004390230.019
response to organic cyclic compoundGO:0014070510.019
regulation of cytoplasmic transportGO:190364940.018
Yeast
neuroblast fate determinationGO:000740010.018
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.018
negative regulation of nitrogen compound metabolic processGO:0051172590.018
regulation of organelle assemblyGO:190211540.017
Yeast
muscle structure developmentGO:00610611960.017
regulation of cellular amino acid metabolic processGO:000652100.017
positive regulation of cell divisionGO:005178120.017
regulation of transcription from rna polymerase ii promoterGO:00063571140.017
negative regulation of macromolecule biosynthetic processGO:0010558480.016
negative regulation of cell cycleGO:0045786140.016
Yeast
agingGO:000756820.016
regulation of embryonic developmentGO:0045995470.016
protein import into nucleusGO:000660630.016
Yeast
positive regulation of cellular protein metabolic processGO:0032270220.016
negative regulation of protein maturationGO:1903318100.016
microtubule cytoskeleton organizationGO:0000226330.016
positive regulation of gene expressionGO:0010628710.016
membrane organizationGO:0061024210.016
regulation of protein bindingGO:004339330.016
protein localization to centrosomeGO:007153910.016
system processGO:00030081850.015
nucleotide metabolic processGO:0009117280.015
negative regulation of rna biosynthetic processGO:1902679450.015
single organism cellular localizationGO:1902580460.015
Yeast
regulation of molecular functionGO:0065009700.015
cellular component morphogenesisGO:00329893360.015
metaphase plate congressionGO:005131020.015
negative regulation of nucleic acid templated transcriptionGO:1903507450.015
response to endogenous stimulusGO:0009719830.015
Yeast
posttranscriptional regulation of gene expressionGO:0010608140.015
cell morphogenesis involved in neuron differentiationGO:00486671630.015
embryonic organ developmentGO:00485683810.015
interspecies interaction between organismsGO:004441940.015
hematopoietic or lymphoid organ developmentGO:00485341910.014
negative regulation of cell divisionGO:005178240.014
peptidyl amino acid modificationGO:0018193160.014
Worm
aromatic compound catabolic processGO:0019439150.014
homeostasis of number of cellsGO:0048872620.014
developmental cell growthGO:0048588520.014
amine metabolic processGO:000930820.014
positive regulation of cellular biosynthetic processGO:0031328680.014
cellular response to light stimulusGO:007148240.014
regulation of histone modificationGO:003105650.013
positive regulation of cellular component organizationGO:0051130130.013
cellular response to biotic stimulusGO:007121630.013
Yeast
small gtpase mediated signal transductionGO:000726480.013
regulation of protein modification processGO:0031399290.013
cellular amine metabolic processGO:004410620.013
cardiac muscle cell developmentGO:0055013200.013
hemopoiesisGO:00300971830.013
chromatin organizationGO:0006325220.013
rna transportGO:005065820.013
regulation of purine nucleotide catabolic processGO:003312120.012
pyrimidine containing compound metabolic processGO:007252730.012
regulation of protein depolymerizationGO:190187910.012
developmental growth involved in morphogenesisGO:0060560860.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
Yeast
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.012
regulation of cell maturationGO:190342910.012
protein phosphorylationGO:0006468470.012
Human Yeast Worm
regulation of cellular amine metabolic processGO:003323800.012
cellular amino acid metabolic processGO:000652070.012
macromolecule localizationGO:0033036540.011
Yeast Worm
posttranscriptional gene silencingGO:001644130.011
signal transductionGO:00071654550.011
behaviorGO:0007610740.011
regulation of cell divisionGO:0051302120.011
Yeast Worm
regulation of neural precursor cell proliferationGO:200017730.011
guanosine containing compound catabolic processGO:190106920.011
posttranscriptional gene silencing by rnaGO:003519430.011
specification of symmetryGO:00097992040.011
lateral inhibitionGO:004633110.011
guanosine containing compound metabolic processGO:190106840.011
striated muscle cell developmentGO:00550021080.011
vesicle mediated transportGO:0016192220.010
cellular protein complex assemblyGO:0043623190.010
Worm
regulation of nucleotide catabolic processGO:003081120.010
regulation of synapse organizationGO:005080730.010
dna integrity checkpointGO:003157060.010
Yeast

aurkb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.093
organ system cancerDOID:005068600.065
cancerDOID:16200.065
large intestine cancerDOID:567200.030
intestinal cancerDOID:1015500.030
gastrointestinal system cancerDOID:311900.030
thoracic cancerDOID:509300.011