Danio rerio

20 known processes

c3b

complement component c3b

(Aliases: C3-1,C3-2)

c3b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
activation of immune responseGO:000225390.844
protein activation cascadeGO:007237660.757
complement activationGO:000695630.721
positive regulation of immune system processGO:0002684170.597
phagocytosisGO:000690930.493
positive regulation of immune responseGO:0050778110.401
regulation of cytokine productionGO:000181730.380
regulation of immune system processGO:0002682340.348
lipid storageGO:001991510.316
positive regulation of cytokine productionGO:000181920.303
immune effector processGO:0002252230.300
humoral immune responseGO:000695950.285
immune system processGO:00023762410.280
positive regulation of transportGO:005105020.272
maintenance of locationGO:005123540.193
regulation of immune responseGO:0050776140.138
positive regulation of response to stimulusGO:0048584800.133
g protein coupled receptor signaling pathwayGO:0007186740.132
immune responseGO:0006955280.126
signal transductionGO:00071654550.115
cellular biosynthetic processGO:00442492860.102
regulation of multicellular organismal processGO:00512392770.101
regulation of response to stimulusGO:00485832690.093
carbohydrate transportGO:0008643130.092
establishment of localizationGO:00512342440.091
regulation of glucose transportGO:001082710.090
protein metabolic processGO:00195381830.089
response to stressGO:00069502630.089
single organism transportGO:00447652060.086
regulation of vesicle mediated transportGO:006062790.079
defense responseGO:0006952470.077
cell surface receptor signaling pathwayGO:00071663250.076
regulation of gene expressionGO:00104682650.073
regulation of biosynthetic processGO:00098892500.069
positive regulation of glucose transportGO:001082810.068
agingGO:000756820.067
positive regulation of biological processGO:00485182530.062
regulation of primary metabolic processGO:00800903110.059
biosynthetic processGO:00090582940.058
transportGO:00068102200.057
cellular macromolecule metabolic processGO:00442603910.056
regulation of cellular biosynthetic processGO:00313262450.055
regulation of metabolic processGO:00192223590.055
organic substance biosynthetic processGO:19015762890.054
larval developmentGO:000216420.053
single organism metabolic processGO:00447102170.053
regulation of cellular metabolic processGO:00313233200.050
regulation of endocytosisGO:003010070.050
protein modification processGO:00362111000.050
regulation of macromolecule metabolic processGO:00602553170.049
cellular response to external stimulusGO:007149620.048
regulation of signalingGO:00230512350.046
glycerolipid biosynthetic processGO:004501710.044
multicellular organism growthGO:003526440.043
regulation of cell communicationGO:00106462320.041
immunoglobulin mediated immune responseGO:001606430.041
regulation of signal transductionGO:00099662250.040
apoptotic processGO:00069151160.039
positive regulation of secretion by cellGO:190353210.036
regulation of multicellular organism growthGO:004001440.035
lipid biosynthetic processGO:0008610220.035
regulation of protein transportGO:005122330.034
single organism nuclear importGO:190259330.034
positive regulation of cellular processGO:00485222010.033
autophagyGO:000691440.033
positive regulation of multicellular organismal processGO:0051240520.032
response to external biotic stimulusGO:0043207970.032
nucleocytoplasmic transportGO:000691340.032
positive regulation of immune effector processGO:000269930.031
proteolysis involved in cellular protein catabolic processGO:005160330.031
cellular response to extracellular stimulusGO:003166820.031
angiogenesisGO:00015251580.030
blood vessel morphogenesisGO:00485142160.030
positive regulation of cellular metabolic processGO:0031325940.030
negative regulation of biological processGO:00485193040.030
nuclear transportGO:005116940.030
response to monosaccharideGO:003428430.029
vasculature developmentGO:00019442780.029
regulation of establishment of protein localizationGO:007020140.029
multi organism processGO:00517041340.029
cellular protein catabolic processGO:004425740.029
ameboidal type cell migrationGO:00016671430.029
response to carbohydrateGO:000974330.029
leukocyte mediated cytotoxicityGO:000190910.028
leukocyte proliferationGO:007066110.028
regulation of cellular component organizationGO:0051128860.028
regulation of developmental processGO:00507932470.027
hexose transportGO:000864560.027
protein import into nucleusGO:000660630.027
regulation of inflammatory responseGO:005072720.026
protein importGO:001703830.026
protein targeting to nucleusGO:004474430.026
nuclear importGO:005117030.026
establishment of protein localization to organelleGO:007259440.026
defense response to other organismGO:0098542330.025
cellular response to starvationGO:000926710.025
positive regulation of lymphocyte mediated immunityGO:000270810.025
blood vessel developmentGO:00015682460.025
positive regulation of cell activationGO:005086710.025
programmed cell deathGO:00125011190.025
glucose transportGO:001575860.025
stem cell proliferationGO:007208940.024
positive regulation of leukocyte mediated cytotoxicityGO:000191210.024
digestive tract morphogenesisGO:00485462310.024
cell motilityGO:00488702440.024
tube morphogenesisGO:00352393490.024
cellular response to molecule of bacterial originGO:007121930.024
hematopoietic or lymphoid organ developmentGO:00485341910.024
cellular response to lipopolysaccharideGO:007122230.024
response to hexoseGO:000974630.023
protein localization to nucleusGO:003450430.023
macromolecule modificationGO:00434121110.023
regulation of cellular amine metabolic processGO:003323800.023
cellular lipid metabolic processGO:0044255360.023
regulation of reactive oxygen species metabolic processGO:200037720.023
gastrulationGO:00073692080.023
reactive oxygen species biosynthetic processGO:190340910.023
regulation of wound healingGO:006104120.023
regulation of leukocyte mediated immunityGO:000270310.022
regulation of cell activationGO:005086510.022
monosaccharide transportGO:001574960.022
cellular protein modification processGO:00064641000.022
regulation of cellular protein metabolic processGO:0032268520.022
amine metabolic processGO:000930820.022
transcription dna templatedGO:00063511810.022
heterocycle metabolic processGO:00464832900.022
mesenchymal cell differentiationGO:0048762870.022
regulation of biological qualityGO:00650082630.022
response to alkaloidGO:004327920.022
response to external stimulusGO:00096052640.021
circadian sleep wake cycleGO:004274520.021
cellular protein metabolic processGO:00442671290.021
wound healingGO:0042060900.021
regulation of protein ubiquitinationGO:003139630.021
positive regulation of inflammatory responseGO:005072910.021
digestive system developmentGO:00551232890.021
positive regulation of dna metabolic processGO:005105410.021
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.021
growthGO:00400071740.021
cellular response to nutrient levelsGO:003166920.021
regulation of localizationGO:00328791040.020
b cell mediated immunityGO:001972430.020
peptide transportGO:001583310.020
regulation of tube sizeGO:003515020.020
gtp metabolic processGO:004603940.020
modification dependent macromolecule catabolic processGO:004363230.020
regulation of cytoplasmic transportGO:190364940.020
modification dependent protein catabolic processGO:001994130.020
regulation of programmed cell deathGO:00430671010.020
sensory organ developmentGO:00074233930.020
lipid metabolic processGO:0006629520.020
symbiosis encompassing mutualism through parasitismGO:004440340.020
ubiquitin dependent protein catabolic processGO:000651130.020
cell killingGO:000190620.020
aromatic compound biosynthetic processGO:00194382170.020
response to glucoseGO:000974930.020
interspecies interaction between organismsGO:004441940.020
guanosine containing compound catabolic processGO:190106920.019
defense response to bacteriumGO:0042742220.019
hemopoiesisGO:00300971830.019
regulation of blood vessel sizeGO:005088020.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.019
positive regulation of protein metabolic processGO:0051247230.019
negative regulation of protein phosphorylationGO:000193340.019
regulation of nucleobase containing compound metabolic processGO:00192192500.019
positive regulation of macromolecule metabolic processGO:0010604930.019
mononuclear cell proliferationGO:003294310.019
glucose importGO:004632320.018
regulation of autophagyGO:001050630.018
lymphocyte proliferationGO:004665110.018
regulation of apoptotic processGO:0042981980.018
proteasomal protein catabolic processGO:001049820.018
protein secretionGO:000930610.018
localization of cellGO:00516742440.018
embryonic organ developmentGO:00485683810.018
regulation of cell killingGO:003134120.018
positive regulation of secretionGO:005104710.018
response to woundingGO:00096111160.018
gene expressionGO:00104672520.018
nucleic acid templated transcriptionGO:00976591810.018
locomotionGO:00400113130.018
cellular amine metabolic processGO:004410620.018
regulation of dna replicationGO:000627530.018
rna metabolic processGO:00160702190.017
cell migrationGO:00164772370.017
protein acetylationGO:000647320.017
response to other organismGO:0051707970.017
regulation of protein complex assemblyGO:004325430.017
organic cyclic compound biosynthetic processGO:19013622230.017
positive regulation of map kinase activityGO:004340630.017
regulation of cellular amino acid metabolic processGO:000652100.017
response to bacteriumGO:0009617580.017
mitochondrion organizationGO:000700540.017
negative regulation of catabolic processGO:000989530.017
positive regulation of cell communicationGO:0010647560.017
organonitrogen compound metabolic processGO:1901564740.017
nucleic acid metabolic processGO:00903042440.017
cytokine productionGO:000181640.017
positive regulation of signalingGO:0023056560.016
nitric oxide metabolic processGO:004620920.016
regulation of protein metabolic processGO:0051246560.016
regulation of intracellular protein transportGO:003315730.016
sensory perception of chemical stimulusGO:000760630.016
inositol lipid mediated signalingGO:004801720.016
cell deathGO:00082191210.016
positive regulation of metabolic processGO:00098931080.016
somatic muscle developmentGO:000752540.016
negative regulation of cellular catabolic processGO:003133030.016
cellular nitrogen compound metabolic processGO:00346412900.016
pyruvate metabolic processGO:000609010.016
phosphorus metabolic processGO:00067931090.016
positive regulation of signal transductionGO:0009967560.016
neural crest cell migrationGO:0001755420.016
organic acid metabolic processGO:0006082310.016
organism emergence from protective structureGO:007168440.016
regulation of protein import into nucleusGO:004230620.016
gtp catabolic processGO:000618420.016
regulation of protein catabolic processGO:004217610.016
cell migration involved in gastrulationGO:0042074790.016
glucose homeostasisGO:004259310.016
regulation of bindingGO:005109830.016
organic substance transportGO:0071702580.016
regulation of cell deathGO:00109411030.016
regulation of circadian rhythmGO:004275240.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
mitotic dna damage checkpointGO:004477340.016
positive regulation of leukocyte mediated immunityGO:000270510.015
response to glucocorticoidGO:005138410.015
cellular response to biotic stimulusGO:007121630.015
macromolecule biosynthetic processGO:00090592270.015
regulation of protein targetingGO:190353320.015
regulation of circadian sleep wake cycle sleepGO:004518710.015
b cell activationGO:004211320.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
regulation of cellular ketone metabolic processGO:001056570.015
neuron differentiationGO:00301823530.015
phosphate containing compound metabolic processGO:00067961080.015
neural crest cell differentiationGO:0014033720.015
oxoacid metabolic processGO:0043436310.015
cellular amide metabolic processGO:004360340.015
ear developmentGO:00435831270.015
female sex differentiationGO:004666040.014
response to nutrientGO:000758430.014
regulation of nucleocytoplasmic transportGO:004682220.014
reactive nitrogen species metabolic processGO:200105700.014
regulation of nitrogen compound metabolic processGO:00511712510.014
cellular nitrogen compound biosynthetic processGO:00442712180.014
membrane invaginationGO:001032410.014
neuron neuron synaptic transmissionGO:000727010.014
negative regulation of defense responseGO:003134820.014
macroautophagyGO:001623610.014
regulation of cellular protein catabolic processGO:190336210.014
immune system developmentGO:00025201910.014
regulation of reproductive processGO:200024140.014
single organism localizationGO:19025782250.014
peptidyl lysine acetylationGO:001839420.014
positive regulation of catabolic processGO:000989640.014
leukocyte mediated immunityGO:000244360.014
peptidyl serine phosphorylationGO:001810510.014
guanosine containing compound metabolic processGO:190106840.014
response to drugGO:004249330.014
cellular carbohydrate metabolic processGO:004426240.014
adult behaviorGO:003053420.014
cellular component movementGO:00069283350.014
mesenchyme developmentGO:00604851270.014
carboxylic acid metabolic processGO:0019752220.014
meiotic cell cycle processGO:190304630.014
digestive tract developmentGO:00485652650.014
multicellular organismal response to stressGO:003355520.014
positive regulation of cell cycleGO:004578730.014
protein acylationGO:004354330.014
response to vitaminGO:003327330.014
i kappab kinase nf kappab signalingGO:000724940.014
peptide metabolic processGO:000651810.014
regulation of phosphorus metabolic processGO:0051174430.013
negative regulation of cytokine productionGO:000181810.013
nitrogen compound metabolic processGO:00068073190.013
positive regulation of cell killingGO:003134320.013
nucleobase containing compound biosynthetic processGO:00346542050.013
hatchingGO:003518840.013
brain developmentGO:00074202930.013
innate immune responseGO:0045087130.013
cognitionGO:005089010.013
internal peptidyl lysine acetylationGO:001839320.013
protein polyubiquitinationGO:000020940.013
antimicrobial humoral responseGO:001973020.013
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.013
regulation of anatomical structure morphogenesisGO:00226031300.013
endosomal transportGO:001619720.013
stem cell divisionGO:001714510.013
phagocytosis engulfmentGO:000691110.013
embryonic organ morphogenesisGO:00485622740.013
dicarboxylic acid transportGO:000683510.013
cellular monovalent inorganic cation homeostasisGO:003000420.013
regulation of synaptic plasticityGO:004816710.013
regulation of leukocyte mediated cytotoxicityGO:000191010.013
single fertilizationGO:000733830.013
regulation of rna metabolic processGO:00512522240.013
response to biotic stimulusGO:0009607970.013
nucleobase containing compound metabolic processGO:00061392740.013
toll like receptor signaling pathwayGO:000222440.013
phosphatidylinositol mediated signalingGO:004801520.013
positive regulation of cellular component biogenesisGO:004408930.013
chordate embryonic developmentGO:00430092710.013
sleepGO:003043110.013
regulation of phGO:000688530.013
response to corticosteroidGO:003196010.013
heart developmentGO:00075073130.013
positive regulation of myeloid cell differentiationGO:004563920.013
erk1 and erk2 cascadeGO:007037140.013
response to abiotic stimulusGO:00096281220.013
inner ear developmentGO:00488391260.013
developmental growthGO:00485891660.013
deathGO:00162651210.013
cellular ketone metabolic processGO:0042180110.013
positive regulation of cellular amine metabolic processGO:003324000.013
regenerationGO:0031099910.013
regulation of transportGO:0051049450.013
negative regulation of protein kinase activityGO:000646940.013
regulation of protein maturationGO:1903317100.012
internal protein amino acid acetylationGO:000647520.012
negative regulation of programmed cell deathGO:0043069580.012
regulation of jak stat cascadeGO:004642530.012
small molecule metabolic processGO:0044281770.012
circadian sleep wake cycle sleepGO:005080210.012
pericardium developmentGO:006003910.012
regulation of multicellular organismal developmentGO:20000262230.012
negative regulation of response to stimulusGO:00485851040.012
cellular component disassemblyGO:002241110.012
regulation of response to extracellular stimulusGO:003210410.012
natural killer cell mediated cytotoxicityGO:004226710.012
regulation of production of molecular mediator of immune responseGO:000270010.012
cytokinesisGO:000091030.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
regulation of natural killer cell mediated immunityGO:000271510.012
tissue remodelingGO:004877140.012
regulation of protein localization to nucleusGO:190018020.012
carbohydrate homeostasisGO:003350010.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
morphogenesis of an epitheliumGO:00020093330.012
negative regulation of autophagyGO:001050710.012
development of primary female sexual characteristicsGO:004654540.012
modification of morphology or physiology of other organismGO:003582140.012
protein phosphorylationGO:0006468470.012
tissue regenerationGO:0042246740.012
heterocycle biosynthetic processGO:00181302150.012
nitric oxide biosynthetic processGO:000680920.012
regulation of hormone secretionGO:004688320.012
regulation of transporter activityGO:003240920.012
humoral immune response mediated by circulating immunoglobulinGO:000245530.012
protein stabilizationGO:005082120.012
peptidyl serine modificationGO:001820920.012
regulation of circadian sleep wake cycleGO:004274910.012
liver developmentGO:0001889960.012
positive regulation of cell adhesionGO:004578510.012
somatic cell dna recombinationGO:001644410.012
intracellular signal transductionGO:0035556850.012
organic cyclic compound metabolic processGO:19013603010.011
ribonucleoside monophosphate catabolic processGO:000915840.011
hormone secretionGO:004687920.011
skeletal system developmentGO:00015011810.011
negative regulation of cellular processGO:00485232830.011
regulation of protein bindingGO:004339330.011
regulation of innate immune responseGO:0045088110.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
response to hydrogen peroxideGO:004254230.011
regulation of rna biosynthetic processGO:20011412130.011
stem cell maintenanceGO:001982740.011
central nervous system developmentGO:00074173870.011
negative regulation of macromolecule metabolic processGO:0010605760.011
regulation of lipid biosynthetic processGO:004689080.011
positive regulation of wound healingGO:009030310.011
extrinsic apoptotic signaling pathwayGO:009719130.011
cellular aromatic compound metabolic processGO:00067252950.011
negative regulation of multi organism processGO:004390130.011
phosphatidylinositol 3 kinase signalingGO:001406520.011
neural crest cell developmentGO:0014032620.011
hormone transportGO:000991420.011
response to virusGO:0009615210.011
ribonucleoside triphosphate biosynthetic processGO:000920120.011
cell cycle g1 s phase transitionGO:004484310.011
estrogen metabolic processGO:000821020.011
rna biosynthetic processGO:00327741810.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
sulfur compound transportGO:007234830.011
determination of bilateral symmetryGO:00098552040.011
spermatid developmentGO:000728620.011
spermatid differentiationGO:004851520.011
membrane repolarizationGO:008600920.011
collagen metabolic processGO:003296320.011
cellular response to chemical stimulusGO:00708871570.011
sensory perception of painGO:001923310.011
negative regulation of protein transportGO:005122430.011
meiotic nuclear divisionGO:000712640.011
regulation of stem cell proliferationGO:007209120.010
negative regulation of protein localization to nucleusGO:190018120.010
production of molecular mediator of immune responseGO:000244020.010
homeostatic processGO:00425921420.010
positive regulation of leukocyte differentiationGO:190210710.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
dorsal ventral pattern formationGO:00099531250.010
specification of symmetryGO:00097992040.010
response to chemicalGO:00422213200.010
positive regulation of i kappab kinase nf kappab signalingGO:004312330.010
cellular respirationGO:004533330.010
negative regulation of cell deathGO:0060548600.010
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.010
regulation of response to external stimulusGO:0032101310.010
positive regulation of blood circulationGO:190352420.010
positive regulation of stem cell proliferationGO:200064810.010
head developmentGO:00603223030.010
neurotransmitter secretionGO:000726920.010
positive regulation of cell divisionGO:005178120.010
regulation of metal ion transportGO:001095940.010
dna templated transcription elongationGO:000635430.010
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.010

c3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.156
nervous system diseaseDOID:86300.156
eye diseaseDOID:561400.138
sensory system diseaseDOID:005015500.138
eye and adnexa diseaseDOID:149200.138
immune system diseaseDOID:291400.076
hematopoietic system diseaseDOID:7400.076
retinal diseaseDOID:567900.065
retinal degenerationDOID:846600.048
disease of metabolismDOID:001466700.019
anemiaDOID:235500.016
inherited metabolic disorderDOID:65500.013