Danio rerio

46 known processes

ca2

carbonic anhydrase II

(Aliases: wu:fk91a02,cb1082,wu:fb50f02)

ca2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of phGO:000688530.976
monovalent inorganic cation transportGO:0015672420.975
cation homeostasisGO:0055080330.972
ion transportGO:00068111140.956
monovalent inorganic cation homeostasisGO:005506790.949
sodium ion transportGO:0006814240.917
hypotonic responseGO:000697150.906
ion homeostasisGO:0050801410.880
regulation of cellular phGO:003064110.868
Mouse
metal ion transportGO:0030001580.864
chloride transportGO:000682180.848
Mouse
inorganic cation transmembrane transportGO:0098662500.843
hypotonic salinity responseGO:004253950.837
homeostatic processGO:00425921420.831
ion transmembrane transportGO:0034220910.831
response to osmotic stressGO:0006970110.829
single organism transportGO:00447652060.826
cation transmembrane transportGO:0098655650.788
one carbon compound transportGO:0019755140.764
transmembrane transportGO:00550851200.736
sodium ion importGO:009736930.725
response to salt stressGO:0009651100.711
carbon dioxide transportGO:001567030.663
response to chemicalGO:00422213200.584
agingGO:000756820.579
organic cyclic compound metabolic processGO:19013603010.575
heart morphogenesisGO:00030071560.568
embryo development ending in birth or egg hatchingGO:00097922710.545
single organism localizationGO:19025782250.501
transportGO:00068102200.488
cell motilityGO:00488702440.487
cellular nitrogen compound metabolic processGO:00346412900.485
response to metal ionGO:0010038340.466
establishment of localizationGO:00512342440.427
response to transition metal nanoparticleGO:1990267280.418
response to abiotic stimulusGO:00096281220.408
chemical homeostasisGO:0048878490.402
regulation of cellular metabolic processGO:00313233200.400
response to stressGO:00069502630.397
cell migrationGO:00164772370.395
inorganic ion transmembrane transportGO:0098660570.394
response to drugGO:004249330.392
negative regulation of biological processGO:00485193040.388
lateral line developmentGO:0048882660.385
cellular amide metabolic processGO:004360340.344
nitrogen compound metabolic processGO:00068073190.335
regulation of response to stimulusGO:00485832690.327
bicarbonate transportGO:001570140.325
brain developmentGO:00074202930.320
Zebrafish
anion homeostasisGO:005508190.309
regulation of macromolecule metabolic processGO:00602553170.291
regulation of endothelial cell proliferationGO:000193610.281
embryonic organ morphogenesisGO:00485622740.272
response to phGO:000926820.271
morphogenesis of an epitheliumGO:00020093330.268
Mouse
cellular response to xenobiotic stimulusGO:0071466350.262
cellular response to external stimulusGO:007149620.253
muscle organ developmentGO:00075171010.249
response to xenobiotic stimulusGO:0009410450.245
behaviorGO:0007610740.244
Zebrafish
ammonia homeostasisGO:009727230.244
cellular macromolecule metabolic processGO:00442603910.241
ammonium transmembrane transportGO:007248820.240
head developmentGO:00603223030.240
Zebrafish
neuromast developmentGO:0048884460.238
central nervous system developmentGO:00074173870.235
Zebrafish
larval developmentGO:000216420.232
heart developmentGO:00075073130.227
response to hormoneGO:0009725480.221
sodium ion transmembrane transportGO:0035725210.215
signal transductionGO:00071654550.211
Human
positive regulation of cellular processGO:00485222010.207
Mouse
regulation of metabolic processGO:00192223590.206
response to decreased oxygen levelsGO:0036293250.206
response to nutrientGO:000758430.202
regulation of sodium ion transportGO:000202820.189
locomotionGO:00400113130.187
Worm
system processGO:00030081850.176
multicellular organism growthGO:003526440.175
regulation of actin filament based movementGO:190311510.167
gene expressionGO:00104672520.166
cellular response to extracellular stimulusGO:003166820.166
regulation of rna biosynthetic processGO:20011412130.164
regulation of transcription dna templatedGO:00063552130.163
nucleic acid templated transcriptionGO:00976591810.161
regulation of metal ion transportGO:001095940.161
sympathetic nervous system developmentGO:004848530.160
ameboidal type cell migrationGO:00016671430.157
sensory system developmentGO:0048880760.156
generation of neuronsGO:00486993850.152
response to organic cyclic compoundGO:0014070510.149
cellular response to prostaglandin stimulusGO:007137930.147
heterocycle biosynthetic processGO:00181302150.145
cellular response to chemical stimulusGO:00708871570.145
organic anion transportGO:0015711150.145
response to vitaminGO:003327330.144
regulation of muscle contractionGO:000693730.136
lateral line system developmentGO:0048925760.135
cellular nitrogen compound biosynthetic processGO:00442712180.134
response to external stimulusGO:00096052640.130
cellular response to organic substanceGO:00713101050.129
anion transportGO:0006820380.128
Human Mouse
regulation of nitrogen compound metabolic processGO:00511712510.127
cellular ion homeostasisGO:0006873170.125
Mouse
regulation of biological qualityGO:00650082630.124
ammonium transportGO:001569660.120
inorganic anion transportGO:0015698250.119
Mouse
regulation of synaptic plasticityGO:004816710.117
cellular cation homeostasisGO:0030003170.116
Mouse
regulation of multicellular organism growthGO:004001440.114
cellular amine metabolic processGO:004410620.114
embryonic heart tube developmentGO:00350501330.113
response to glucocorticoidGO:005138410.111
response to mechanical stimulusGO:0009612240.111
mononuclear cell proliferationGO:003294310.111
regulation of establishment of protein localizationGO:007020140.110
embryonic organ developmentGO:00485683810.110
response to vitamin b3GO:003355220.110
heterocycle metabolic processGO:00464832900.109
regulation of blood pressureGO:000821710.102
tube morphogenesisGO:00352393490.102
rna biosynthetic processGO:00327741810.098
response to extracellular stimulusGO:0009991100.097
nucleic acid metabolic processGO:00903042440.097
cation transportGO:0006812810.097
response to alkaloidGO:004327920.097
positive regulation of cell activationGO:005086710.093
divalent inorganic cation homeostasisGO:0072507220.093
regulation of nucleic acid templated transcriptionGO:19035062130.093
regulation of molecular functionGO:0065009700.093
cellular biosynthetic processGO:00442492860.092
regulation of neuronal synaptic plasticityGO:004816810.092
regulation of sequence specific dna binding transcription factor activityGO:005109090.092
membrane repolarizationGO:008600920.091
positive regulation of transportGO:005105020.087
Mouse
locomotory behaviorGO:0007626340.086
Zebrafish
regulation of cellular biosynthetic processGO:00313262450.085
rna metabolic processGO:00160702190.085
digestive tract morphogenesisGO:00485462310.083
response to steroid hormoneGO:0048545350.083
cellular response to nutrient levelsGO:003166920.082
response to inorganic substanceGO:0010035380.080
multi organism processGO:00517041340.079
regulation of biosynthetic processGO:00098892500.079
response to estradiolGO:003235560.078
regulation of wound healingGO:006104120.077
localization of cellGO:00516742440.077
cellular monovalent inorganic cation homeostasisGO:003000420.077
Mouse
muscle tissue developmentGO:00605371100.076
nucleobase containing compound metabolic processGO:00061392740.076
response to endogenous stimulusGO:0009719830.075
water homeostasisGO:003010440.075
protein metabolic processGO:00195381830.074
regionalizationGO:00030022740.074
positive regulation of signalingGO:0023056560.073
Mouse
reactive oxygen species biosynthetic processGO:190340910.073
organelle organizationGO:00069962270.073
interferon beta productionGO:003260810.073
cellular component movementGO:00069283350.072
protein secretionGO:000930610.072
response to lipidGO:0033993600.071
transcription dna templatedGO:00063511810.069
regulation of signal transductionGO:00099662250.069
regulation of developmental processGO:00507932470.068
positive regulation of nitrogen compound metabolic processGO:0051173690.067
single organism cell adhesionGO:0098602290.067
regulation of signalingGO:00230512350.066
Mouse
regulation of intracellular phGO:005145310.066
Mouse
negative regulation of multicellular organismal processGO:0051241690.066
positive regulation of cell adhesionGO:004578510.066
response to fatty acidGO:007054250.066
regulation of heart contractionGO:0008016320.066
maintenance of locationGO:005123540.065
single organism organelle organizationGO:19025891990.065
response to corticosteroidGO:003196010.065
regulation of blood circulationGO:1903522320.065
intracellular receptor signaling pathwayGO:0030522300.064
cognitionGO:005089010.063
regulation of peptidyl tyrosine phosphorylationGO:005073010.063
response to oxygen containing compoundGO:1901700550.062
regulation of cardiac muscle tissue developmentGO:005502410.062
response to alcoholGO:0097305140.061
aromatic compound biosynthetic processGO:00194382170.061
hydrogen peroxide metabolic processGO:004274320.060
cellular homeostasisGO:0019725260.060
Mouse
hormone mediated signaling pathwayGO:000975590.059
biosynthetic processGO:00090582940.059
regulation of primary metabolic processGO:00800903110.058
skeletal system developmentGO:00015011810.057
circulatory system processGO:0003013870.057
epithelial tube morphogenesisGO:00605621480.056
regulation of rna metabolic processGO:00512522240.056
peptide transportGO:001583310.055
Mouse
regulation of erk1 and erk2 cascadeGO:007037240.055
establishment of localization in cellGO:0051649770.055
response to acidic phGO:001044720.054
digestive system developmentGO:00551232890.054
negative regulation of protein phosphorylationGO:000193340.053
regulation of intracellular signal transductionGO:1902531570.052
synaptic transmissionGO:0007268350.052
Mouse
intracellular signal transductionGO:0035556850.052
regulation of cellular macromolecule biosynthetic processGO:20001122220.051
cell morphogenesisGO:00009022890.050
negative regulation of cytokine mediated signaling pathwayGO:000196020.049
cranial nerve developmentGO:0021545420.048
regulation of interferon beta productionGO:003264810.048
catechol containing compound metabolic processGO:000971220.048
cellular response to hormone stimulusGO:0032870390.047
regulation of cell activationGO:005086510.047
gamete generationGO:0007276330.046
positive regulation of metabolic processGO:00098931080.046
metal ion homeostasisGO:0055065260.046
regulation of cell communicationGO:00106462320.045
Mouse
response to hypoxiaGO:0001666250.045
organonitrogen compound metabolic processGO:1901564740.045
reproductionGO:0000003400.045
cellular response to oxygen levelsGO:007145310.045
regulation of macromolecule biosynthetic processGO:00105562250.044
muscle contractionGO:0006936180.044
response to oxygen levelsGO:0070482250.043
multicellular organismal metabolic processGO:004423620.043
adult behaviorGO:003053420.043
biological adhesionGO:0022610400.043
negative regulation of epithelial cell migrationGO:001063310.042
sensory organ developmentGO:00074233930.042
regulation of locomotionGO:0040012550.042
positive regulation of cell cycleGO:004578730.042
positive regulation of cellular amino acid metabolic processGO:004576400.042
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.042
cellular response to fatty acidGO:007139830.042
immune system developmentGO:00025201910.041
regulation of cytokine productionGO:000181730.041
response to monosaccharideGO:003428430.041
cellular response to oxygen containing compoundGO:1901701200.040
neurological system processGO:0050877620.040
eye developmentGO:00016542770.040
fatty acid transportGO:001590810.040
calcium ion homeostasisGO:0055074190.040
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.039
renal absorptionGO:007029310.039
regulation of dna templated transcription in response to stressGO:004362000.038
cellular aromatic compound metabolic processGO:00067252950.038
deathGO:00162651210.038
cellular response to decreased oxygen levelsGO:003629410.037
actin cytoskeleton organizationGO:0030036630.037
membrane hyperpolarizationGO:006008110.037
negative regulation of response to cytokine stimulusGO:006076120.037
heart loopingGO:0001947940.037
regulation of cellular component movementGO:0051270550.037
negative regulation of endothelial cell migrationGO:001059610.037
cell fate commitmentGO:0045165990.037
single organismal cell cell adhesionGO:0016337290.037
intracellular estrogen receptor signaling pathwayGO:003052030.037
positive regulation of biological processGO:00485182530.036
Mouse
cellular sodium ion homeostasisGO:000688310.036
dendrite guidanceGO:007098300.036
smooth muscle contractionGO:000693920.036
positive regulation of programmed cell deathGO:0043068290.036
multicellular organismal water homeostasisGO:005089110.035
response to immobilization stressGO:003590210.035
urea transportGO:0015840110.035
regulation of protein transportGO:005122330.035
cellular response to endogenous stimulusGO:0071495680.035
regulation of striated muscle contractionGO:000694220.035
inner ear developmentGO:00488391260.035
negative regulation of cytokine productionGO:000181810.035
single organism metabolic processGO:00447102170.034
Worm
vesicle mediated transportGO:0016192220.034
macromolecule biosynthetic processGO:00090592270.034
gland developmentGO:00487321430.034
response to foodGO:003209410.034
regulation of cell migrationGO:0030334400.034
amine metabolic processGO:000930820.033
blood circulationGO:0008015870.032
angiogenesisGO:00015251580.032
regulation of protein phosphorylationGO:0001932180.032
response to estrogenGO:0043627270.032
cellular protein metabolic processGO:00442671290.032
cellular macromolecule biosynthetic processGO:00346452240.032
cellular response to lipidGO:0071396390.031
hemopoiesisGO:00300971830.031
liver developmentGO:0001889960.031
nerve developmentGO:0021675450.031
regulation of autophagyGO:001050630.031
cellular response to steroid hormone stimulusGO:0071383310.031
ph reductionGO:004585110.031
Mouse
regulation of gene expressionGO:00104682650.031
determination of bilateral symmetryGO:00098552040.031
regulation of transmembrane transportGO:0034762180.031
Mouse
multi organism reproductive processGO:0044703360.030
potassium ion transmembrane transportGO:0071805100.030
regulation of response to biotic stimulusGO:000283120.030
regulation of transportGO:0051049450.030
Human Mouse
transcription from rna polymerase ii promoterGO:0006366800.030
cellular divalent inorganic cation homeostasisGO:0072503130.030
skeletal muscle organ developmentGO:0060538780.029
negative regulation of protein serine threonine kinase activityGO:007190120.029
cellular component morphogenesisGO:00329893360.029
neuromast hair cell differentiationGO:0048886120.029
sensory perception of painGO:001923310.029
ear developmentGO:00435831270.029
blood vessel developmentGO:00015682460.029
positive regulation of defense response to virus by hostGO:000223000.029
growthGO:00400071740.029
posterior lateral line nerve glial cell differentiationGO:004893150.029
response to ketoneGO:190165410.028
cell cell signalingGO:0007267520.028
Mouse
sodium ion homeostasisGO:005507830.027
response to ethanolGO:004547160.027
negative regulation of mitosisGO:004583930.027
organic substance transportGO:0071702580.027
establishment of endothelial barrierGO:006102830.027
response to carbohydrateGO:000974330.027
positive regulation of locomotionGO:0040017140.027
striated muscle contractionGO:0006941120.027
peptidyl serine phosphorylationGO:001810510.027
divalent inorganic anion homeostasisGO:007250550.026
cellular component assemblyGO:00226071700.026
neuron developmentGO:00486662620.026
response to nicotineGO:003509420.026
chordate embryonic developmentGO:00430092710.026
digestive tract developmentGO:00485652650.026
posterior lateral line developmentGO:0048916380.026
cellular component assembly involved in morphogenesisGO:00109271070.026
macromolecule modificationGO:00434121110.026
cytokine mediated signaling pathwayGO:001922170.026
regulation of cellular ketone metabolic processGO:001056570.026
muscle structure developmentGO:00610611960.026
oxoacid metabolic processGO:0043436310.026
cell maturationGO:0048469230.025
regulation of protein metabolic processGO:0051246560.025
negative regulation of heart contractionGO:004582220.025
regulation of catalytic activityGO:0050790550.025
posterior lateral line nerve glial cell developmentGO:004894150.025
developmental growthGO:00485891660.025
regulation of nucleoside metabolic processGO:000911820.025
s adenosylmethionine metabolic processGO:004650010.025
action potentialGO:0001508190.025
phosphorylationGO:0016310690.025
cellular protein modification processGO:00064641000.025
cellular component maintenanceGO:004395430.025
gtp catabolic processGO:000618420.025
regulation of cellular amine metabolic processGO:003323800.025
positive regulation of gene expressionGO:0010628710.025
response to biotic stimulusGO:0009607970.024
response to organic substanceGO:00100331530.024
positive regulation of cytokine productionGO:000181920.024
gas transportGO:001566930.024
myelination of lateral line nerve axonsGO:004889750.024
neural nucleus developmentGO:0048857150.024
response to superoxideGO:000030320.024
hydrogen transportGO:000681870.024
positive regulation of cellular biosynthetic processGO:0031328680.024
regulation of cellular component organizationGO:0051128860.024
negative regulation of cell communicationGO:0010648960.024
regulation of heart growthGO:006042020.024
positive regulation of erk1 and erk2 cascadeGO:007037420.023
regulation of membrane potentialGO:0042391230.023
cellular response to hypoxiaGO:007145610.023
positive regulation of wound healingGO:009030310.023
lymph vessel morphogenesisGO:0036303250.023
lipid storageGO:001991510.023
positive regulation of lymphocyte mediated immunityGO:000270810.023
lipid digestionGO:004424130.023
epiboly involved in gastrulation with mouth forming secondGO:0055113350.022
regulation of localizationGO:00328791040.022
Human Mouse
female sex differentiationGO:004666040.022
endothelial cell proliferationGO:0001935110.022
lymphocyte proliferationGO:004665110.022
positive regulation of nucleobase containing compound metabolic processGO:0045935690.022
phagocytosisGO:000690930.022
cellular component biogenesisGO:00440851780.022
regulation of cardiac muscle cell contractionGO:008600410.022
negative regulation of cellular processGO:00485232830.022
stem cell fate commitmentGO:004886510.021
regulation of cardiac muscle contractionGO:005511720.021
mitochondrion organizationGO:000700540.021
nucleobase containing compound biosynthetic processGO:00346542050.021
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.021
actin filament based processGO:0030029640.021
negative regulation of locomotionGO:0040013180.021
positive regulation of cytoskeleton organizationGO:005149530.021
mitotic cell cycleGO:0000278640.021
myeloid cell homeostasisGO:0002262560.021
fin morphogenesisGO:0033334530.021
positive regulation of immune system processGO:0002684170.021
regulation of reactive oxygen species metabolic processGO:200037720.020
pigmentationGO:0043473850.020
positive regulation of transcription dna templatedGO:0045893570.020
negative regulation of blood vessel endothelial cell migrationGO:004353710.020
regulation of cytokine mediated signaling pathwayGO:000195930.020
neural crest cell differentiationGO:0014033720.020
hepaticobiliary system developmentGO:0061008980.020
regulation of response to cytokine stimulusGO:006075930.019
nuclear transportGO:005116940.019
autonomic nervous system developmentGO:0048483190.019
regulation of photoreceptor cell differentiationGO:004653220.019
leukocyte differentiationGO:0002521250.019
cellular response to starvationGO:000926710.019
stem cell maintenanceGO:001982740.019
cell deathGO:00082191210.019
heart processGO:0003015710.019
hindbrain developmentGO:0030902910.019
Zebrafish
regulation of calcium ion transportGO:005192420.019
cell proliferationGO:0008283800.019
positive regulation of cellular metabolic processGO:0031325940.019
positive regulation of signal transductionGO:0009967560.019
regulation of myeloid cell differentiationGO:004563780.018
thermosensory behaviorGO:004004010.018
determination of left right symmetryGO:00073681790.018
glucocorticoid biosynthetic processGO:000670410.018
regulation of cell shapeGO:000836010.018
cell migration involved in heart developmentGO:0060973220.018
epithelial cell differentiationGO:00308551160.018
oligodendrocyte differentiationGO:0048709230.018
sexual reproductionGO:0019953360.018
regulation of ion transmembrane transportGO:0034765180.018
positive regulation of secretion by cellGO:190353210.018
negative regulation of protein transportGO:005122430.018
negative regulation of blood circulationGO:190352320.018
nitric oxide metabolic processGO:004620920.018
reactive nitrogen species metabolic processGO:200105700.017
response to temperature stimulusGO:0009266150.017
chloride transmembrane transportGO:190247640.017
striated muscle tissue developmentGO:00147061100.017
regulation of cellular amino acid metabolic processGO:000652100.017
positive regulation of response to stimulusGO:0048584800.017
positive regulation of ras protein signal transductionGO:004657910.017
response to cadmium ionGO:0046686140.017
determination of heart left right asymmetryGO:00613711170.017
oxidative demethylationGO:007098910.017
negative regulation of signalingGO:0023057960.017
negative regulation of nuclear divisionGO:005178430.017
regulation of retina development in camera type eyeGO:190286620.017
myelinationGO:0042552180.017
positive regulation of cellular amine metabolic processGO:003324000.016
cell cycle processGO:0022402530.016
response to other organismGO:0051707970.016
erk1 and erk2 cascadeGO:007037140.016
regulation of system processGO:0044057400.016
astrocyte differentiationGO:004870810.016
response to acid chemicalGO:0001101170.016
wound healingGO:0042060900.016
neural tube developmentGO:0021915620.016
organic substance biosynthetic processGO:19015762890.016
organic cyclic compound biosynthetic processGO:19013622230.016
potassium ion transportGO:0006813100.016
embryonic heart tube morphogenesisGO:00031431080.016
carboxylic acid metabolic processGO:0019752220.016
axonogenesis involved in innervationGO:006038510.016
positive regulation of cell deathGO:0010942290.016
positive regulation of neuron deathGO:190121610.016
cellular nitrogen compound catabolic processGO:0044270150.016
peripheral nervous system developmentGO:0007422550.016
regulation of nucleotide catabolic processGO:003081120.016
response to hexoseGO:000974630.016
sensory organ morphogenesisGO:00905962000.016
negative regulation of leukocyte differentiationGO:190210610.016
mechanosensory lateral line system developmentGO:0048881490.015
nucleocytoplasmic transportGO:000691340.015
macromolecule catabolic processGO:0009057150.015
vasculature developmentGO:00019442780.015
cellular modified amino acid metabolic processGO:000657530.015
amide transportGO:0042886120.015
Mouse
cellular response to topologically incorrect proteinGO:003596720.015
steroid hormone mediated signaling pathwayGO:004340190.015
cell adhesionGO:0007155400.015
multicellular organism reproductionGO:0032504350.015
i kappab kinase nf kappab signalingGO:000724940.015
catabolic processGO:0009056320.015
positive regulation of cell communicationGO:0010647560.015
Mouse
phosphate containing compound metabolic processGO:00067961080.015
gliogenesisGO:0042063450.015
collagen metabolic processGO:003296320.015
protein modification processGO:00362111000.015
myelination of posterior lateral line nerve axonsGO:004893250.014
positive regulation of molecular functionGO:0044093330.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
long chain fatty acid transportGO:001590910.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
regulation of protein complex assemblyGO:004325430.014
aromatic compound catabolic processGO:0019439150.014
ensheathment of neuronsGO:0007272180.014
inorganic anion transmembrane transportGO:0098661100.014
heart contractionGO:0060047710.014
superoxide metabolic processGO:000680120.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014

ca2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.518
Human
neuropathyDOID:87000.110
charcot marie tooth diseaseDOID:1059500.110
nervous system diseaseDOID:86300.110
neuromuscular diseaseDOID:44000.110
charcot marie tooth disease type 4DOID:005054100.110
organ system cancerDOID:005068600.078
cancerDOID:16200.078
disease of cellular proliferationDOID:1456600.078
musculoskeletal system diseaseDOID:1700.065
Human