Danio rerio

27 known processes

cacna1da

calcium channel, voltage-dependent, L type, alpha 1D subunit, a

(Aliases: si:dz136d19.3,cav1.3a,si:dz223c6.1,cacna1d,isl)

cacna1da biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
detection of mechanical stimulus involved in sensory perceptionGO:0050974110.985
detection of mechanical stimulusGO:0050982110.889
detection of external stimulusGO:0009581240.752
detection of stimulusGO:0051606290.707
detection of abiotic stimulusGO:0009582240.686
neuromuscular process controlling balanceGO:005088530.645
sensory perception of mechanical stimulusGO:0050954160.594
reflexGO:006000420.499
neuron neuron synaptic transmissionGO:000727010.492
morphogenesis of an epitheliumGO:00020093330.487
sensory organ developmentGO:00074233930.473
neuron differentiationGO:00301823530.464
transmembrane transportGO:00550851200.386
Zebrafish Mouse Worm
generation of neuronsGO:00486993850.349
cellular component biogenesisGO:00440851780.339
embryonic organ morphogenesisGO:00485622740.337
Zebrafish
sensory perceptionGO:0007600390.329
response to mechanical stimulusGO:0009612240.319
neuron developmentGO:00486662620.296
microtubule based movementGO:0007018330.290
inorganic ion transmembrane transportGO:0098660570.282
Zebrafish Mouse Worm
epithelial cell differentiationGO:00308551160.253
establishment of localizationGO:00512342440.241
Zebrafish Mouse Worm Fly
larval developmentGO:000216420.236
inner ear receptor stereocilium organizationGO:006012280.227
ion transportGO:00068111140.226
Zebrafish Mouse Worm
ion transmembrane transportGO:0034220910.225
Zebrafish Mouse Worm
cilium assemblyGO:0042384580.223
dicarboxylic acid transportGO:000683510.222
equilibrioceptionGO:005095720.217
response to external stimulusGO:00096052640.213
inner ear receptor cell differentiationGO:0060113290.213
regulation of response to cytokine stimulusGO:006075930.204
hair cell differentiationGO:0035315320.199
cilium organizationGO:0044782710.197
regulation of cell shapeGO:000836010.186
single organism organelle organizationGO:19025891990.176
neuron projection developmentGO:00311751800.175
neuromast developmentGO:0048884460.167
auditory receptor cell morphogenesisGO:000209340.163
epidermal cell differentiationGO:0009913360.163
detection of stimulus involved in sensory perceptionGO:0050906210.162
cell projection organizationGO:00300302840.161
endosome organizationGO:000703220.157
regulation of synapse organizationGO:005080730.154
nonmotile primary cilium assemblyGO:003505820.149
regulation of multicellular organism growthGO:004001440.148
tyrosine phosphorylation of stat proteinGO:000726010.142
transportGO:00068102200.141
Zebrafish Mouse Worm Fly
regulation of multicellular organismal processGO:00512392770.140
Zebrafish Mouse
locomotionGO:00400113130.139
inner ear developmentGO:00488391260.139
embryonic organ developmentGO:00485683810.136
Zebrafish
cation transmembrane transportGO:0098655650.135
Zebrafish Mouse Worm
detection of visible lightGO:0009584120.135
epithelial cilium movementGO:0003351150.133
synaptic transmissionGO:0007268350.132
positive regulation of cellular processGO:00485222010.132
inner ear receptor cell developmentGO:0060119200.130
epidermis developmentGO:0008544480.123
cellular component assembly involved in morphogenesisGO:00109271070.119
multicellular organism growthGO:003526440.117
amino acid transportGO:000686520.117
inorganic cation transmembrane transportGO:0098662500.115
Zebrafish Mouse Worm
proteolysis involved in cellular protein catabolic processGO:005160330.114
organelle assemblyGO:00709251100.114
regulation of cellular component organizationGO:0051128860.114
cartilage developmentGO:0051216960.113
synaptic vesicle recyclingGO:003646510.111
neurological system processGO:0050877620.104
cell projection morphogenesisGO:00488582440.102
cell projection assemblyGO:0030031640.102
skin developmentGO:0043588540.098
regulation of ion transmembrane transportGO:0034765180.095
Zebrafish Mouse Worm
cation transportGO:0006812810.093
Zebrafish Mouse Worm
organelle organizationGO:00069962270.091
regulation of neurotransmitter transportGO:005158810.087
endomembrane system organizationGO:0010256130.082
cellular carbohydrate metabolic processGO:004426240.079
tyrosine phosphorylation of stat3 proteinGO:004250310.079
mechanosensory lateral line system developmentGO:0048881490.078
sensory perception of soundGO:000760590.078
synaptic vesicle endocytosisGO:004848810.077
adult behaviorGO:003053420.076
positive regulation of transportGO:005105020.075
cilium morphogenesisGO:0060271850.075
single organism transportGO:00447652060.075
Zebrafish Mouse Worm Fly
locomotory behaviorGO:0007626340.074
cell motilityGO:00488702440.073
regulation of synapse assemblyGO:005196330.070
regulation of synapse structure and activityGO:005080350.069
heterocycle metabolic processGO:00464832900.067
organism emergence from protective structureGO:007168440.067
regulation of signalingGO:00230512350.065
golgi vesicle transportGO:004819330.064
detection of mechanical stimulus involved in sensory perception of soundGO:005091030.063
regulation of jak stat cascadeGO:004642530.063
synaptic vesicle localizationGO:009747910.060
cellular amine metabolic processGO:004410620.059
regulation of synaptic growth at neuromuscular junctionGO:000858210.059
cell part morphogenesisGO:00329902460.057
cellular component assemblyGO:00226071700.054
central nervous system neuron axonogenesisGO:0021955180.054
positive regulation of biological processGO:00485182530.054
positive regulation of cellular amine metabolic processGO:003324000.054
cellular protein modification processGO:00064641000.053
lateral line system developmentGO:0048925760.052
melanin metabolic processGO:000658220.051
neurotransmitter transportGO:000683620.051
single organism localizationGO:19025782250.050
Zebrafish Mouse Worm Fly
regulation of neurotransmitter secretionGO:004692810.049
inositol phosphate metabolic processGO:004364710.049
regulation of cellular amino acid metabolic processGO:000652100.049
cortical actin cytoskeleton organizationGO:003086610.048
muscle structure developmentGO:00610611960.048
cellular component movementGO:00069283350.048
cellular component disassemblyGO:002241110.047
regulation of transportGO:0051049450.047
Zebrafish Mouse Worm
regulation of establishment of protein localizationGO:007020140.045
embryonic limb morphogenesisGO:003032620.045
epithelial cell morphogenesisGO:000338220.045
carbohydrate metabolic processGO:0005975120.045
regulation of epithelial cell proliferationGO:005067830.044
cilium movementGO:0003341260.044
convergent extension involved in gastrulationGO:0060027710.044
cellular protein catabolic processGO:004425740.044
regulation of biological qualityGO:00650082630.043
Mouse
regulation of neuron differentiationGO:0045664560.043
establishment of protein localization to plasma membraneGO:009000210.043
cytoskeleton organizationGO:0007010960.043
startle responseGO:000196440.043
regulation of ion transmembrane transporter activityGO:003241220.043
Mouse
regulation of reproductive processGO:200024140.042
negative regulation of reproductive processGO:200024230.042
regulation of developmental processGO:00507932470.042
regulation of tyrosine phosphorylation of stat3 proteinGO:004251610.041
macromolecule biosynthetic processGO:00090592270.041
cortical cytoskeleton organizationGO:003086510.041
actin cytoskeleton organizationGO:0030036630.040
negative regulation of response to stimulusGO:00485851040.040
regulation of exocytosisGO:001715710.040
regulation of dendrite morphogenesisGO:004881430.039
positive regulation of cellular amino acid metabolic processGO:004576400.039
regulation of circadian rhythmGO:004275240.038
neurotransmitter secretionGO:000726920.038
negative regulation of response to cytokine stimulusGO:006076120.038
behaviorGO:0007610740.037
Worm
amine metabolic processGO:000930820.037
regulation of neurogenesisGO:0050767870.037
positive regulation of tyrosine phosphorylation of stat3 proteinGO:004251710.037
regulation of dendrite developmentGO:005077330.037
system processGO:00030081850.036
multi organism processGO:00517041340.036
Worm
post golgi vesicle mediated transportGO:000689210.036
reproductive processGO:0022414400.036
Worm
modification dependent macromolecule catabolic processGO:004363230.035
regulation of muscle contractionGO:000693730.035
neuromuscular processGO:005090570.035
ear developmentGO:00435831270.035
positive regulation of signalingGO:0023056560.035
polyol metabolic processGO:001975110.034
synaptic growth at neuromuscular junctionGO:005112420.034
cellular ketone metabolic processGO:0042180110.034
regulation of cell differentiationGO:00455951420.034
sodium ion transportGO:0006814240.033
positive regulation of catabolic processGO:000989640.033
cell morphogenesisGO:00009022890.033
skeletal system developmentGO:00015011810.033
Zebrafish
nitrogen compound transportGO:0071705230.033
renal filtrationGO:0097205100.032
nitrogen compound metabolic processGO:00068073190.032
response to abiotic stimulusGO:00096281220.032
regulation of response to stimulusGO:00485832690.032
Worm
stem cell divisionGO:001714510.032
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.032
small molecule metabolic processGO:0044281770.032
cellular macromolecule metabolic processGO:00442603910.031
regulation of cellular biosynthetic processGO:00313262450.031
nucleus organizationGO:000699770.031
regulation of primary metabolic processGO:00800903110.030
synaptic vesicle transportGO:004848910.030
myofibril assemblyGO:0030239480.029
regulation of cell communicationGO:00106462320.029
mechanoreceptor differentiationGO:0042490370.029
inner ear morphogenesisGO:0042472630.029
negative regulation of synapse assemblyGO:005196420.029
digestive tract developmentGO:00485652650.029
regulation of bindingGO:005109830.029
regulation of cellular ketone metabolic processGO:001056570.029
regulation of tyrosine phosphorylation of stat proteinGO:004250910.029
nuclear transportGO:005116940.028
protein metabolic processGO:00195381830.028
regulation of cell developmentGO:00602841000.028
organic cyclic compound biosynthetic processGO:19013622230.028
regulation of metal ion transportGO:001095940.027
Mouse
cellular protein metabolic processGO:00442671290.027
sensory perception of touchGO:005097520.027
regulation of cytokine mediated signaling pathwayGO:000195930.027
axonogenesisGO:00074091520.027
muscle cell developmentGO:00550011150.027
regulation of macromolecule biosynthetic processGO:00105562250.027
cellular response to chemical stimulusGO:00708871570.027
monovalent inorganic cation transportGO:0015672420.026
Mouse
endocytosisGO:0006897160.026
cell migrationGO:00164772370.026
sodium ion transmembrane transportGO:0035725210.026
response to lipidGO:0033993600.025
regulation of protein bindingGO:004339330.025
exocytosisGO:000688710.025
lateral line developmentGO:0048882660.025
sensory organ morphogenesisGO:00905962000.024
axon developmentGO:00615641660.024
negative regulation of biological processGO:00485193040.024
regulation of protein metabolic processGO:0051246560.024
response to light stimulusGO:0009416460.024
cognitionGO:005089010.024
regulation of nucleoside metabolic processGO:000911820.024
regulation of cellular amine metabolic processGO:003323800.023
spermatid developmentGO:000728620.023
positive regulation of small gtpase mediated signal transductionGO:005105710.023
protein import into nucleusGO:000660630.023
multicellular organism reproductionGO:0032504350.023
Worm
regulation of localizationGO:00328791040.023
Zebrafish Mouse Worm
cellular nitrogen compound metabolic processGO:00346412900.023
oxoacid metabolic processGO:0043436310.023
regulation of cell projection organizationGO:0031344440.022
metal ion transportGO:0030001580.022
Zebrafish Mouse Worm
positive regulation of synapse assemblyGO:005196510.022
gene expressionGO:00104672520.022
developmental maturationGO:0021700340.022
actin filament organizationGO:0007015150.022
compound eye developmentGO:004874920.022
regulation of cell morphogenesis involved in differentiationGO:0010769380.022
dendrite developmentGO:001635890.021
cell morphogenesis involved in neuron differentiationGO:00486671630.021
developmental cell growthGO:0048588520.021
nucleic acid metabolic processGO:00903042440.021
cellular component morphogenesisGO:00329893360.021
regulation of cytoplasmic transportGO:190364940.021
synaptic target recognitionGO:000803910.021
axon guidanceGO:0007411860.021
regulation of synaptic transmissionGO:005080440.021
guanosine containing compound metabolic processGO:190106840.021
directional locomotionGO:003305810.021
regulation of metabolic processGO:00192223590.021
positive regulation of exocytosisGO:004592110.020
positive regulation of signal transductionGO:0009967560.020
gtp metabolic processGO:004603940.020
macromolecule modificationGO:00434121110.020
stem cell proliferationGO:007208940.020
embryonic cranial skeleton morphogenesisGO:0048701900.020
Zebrafish
organic substance biosynthetic processGO:19015762890.020
single organism carbohydrate metabolic processGO:0044723120.020
hatchingGO:003518840.020
purine nucleoside monophosphate catabolic processGO:000912840.020
positive regulation of cellular catabolic processGO:003133130.020
actin filament based movementGO:003004810.020
post embryonic morphogenesisGO:000988640.020
positive regulation of secretion by cellGO:190353210.019
positive regulation of cell communicationGO:0010647560.019
neuroblast proliferationGO:000740520.019
regulation of protein modification by small protein conjugation or removalGO:190332030.019
regulation of wnt signaling pathwayGO:0030111530.019
somatic muscle developmentGO:000752540.019
divalent inorganic cation homeostasisGO:0072507220.019
regulation of synaptic plasticityGO:004816710.019
membrane organizationGO:0061024210.019
posterior lateral line neuromast primordium migrationGO:0048920120.019
organic cyclic compound metabolic processGO:19013603010.019
connective tissue developmentGO:0061448990.019
signal transductionGO:00071654550.019
Mouse
toll like receptor signaling pathwayGO:000222440.018
extrinsic apoptotic signaling pathwayGO:009719130.018
cation homeostasisGO:0055080330.018
regulation of retina development in camera type eyeGO:190286620.018
membrane invaginationGO:001032410.018
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.018
mechanosensory behaviorGO:000763820.018
cellular localizationGO:0051641970.018
positive regulation of response to stimulusGO:0048584800.018
striated muscle cell differentiationGO:00511461290.018
nucleobase containing compound biosynthetic processGO:00346542050.018
positive regulation of apoptotic signaling pathwayGO:200123510.018
muscle cell migrationGO:001481240.018
post embryonic organ morphogenesisGO:004856310.018
cell morphogenesis involved in differentiationGO:00009041950.018
regulation of protein complex disassemblyGO:004324410.018
spindle localizationGO:0051653120.017
peripheral nervous system developmentGO:0007422550.017
energy reserve metabolic processGO:000611220.017
regulation of transmembrane transportGO:0034762180.017
Zebrafish Mouse Worm
organelle transport along microtubuleGO:007238410.017
embryonic hemopoiesisGO:0035162530.017
negative regulation of epithelial cell proliferationGO:005068010.017
modification dependent protein catabolic processGO:001994130.017
chemotaxisGO:00069351040.017
regulation of vesicle mediated transportGO:006062790.017
positive regulation of nucleoside metabolic processGO:004597910.017
regulation of sodium ion transportGO:000202820.017
phagocytosisGO:000690930.017
cell surface receptor signaling pathwayGO:00071663250.017
Mouse
regulation of neuron projection developmentGO:0010975400.017
response to chemicalGO:00422213200.017
cellular response to light stimulusGO:007148240.016
auditory receptor cell developmentGO:006011780.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
l amino acid transportGO:001580710.016
growthGO:00400071740.016
cellular amino acid metabolic processGO:000652070.016
proteasomal protein catabolic processGO:001049820.016
regulation of organ growthGO:004662030.016
negative regulation of protein phosphorylationGO:000193340.016
negative regulation of cytokine mediated signaling pathwayGO:000196020.016
posterior lateral line system developmentGO:0048915460.016
response to radiationGO:0009314510.015
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.015
meiotic nuclear divisionGO:000712640.015
fat soluble vitamin metabolic processGO:000677540.015
actin mediated cell contractionGO:007025210.015
cell deathGO:00082191210.015
axon extensionGO:0048675450.015
neuromuscular synaptic transmissionGO:000727420.015
sarcomere organizationGO:0045214260.015
cardiac atrium developmentGO:000323040.015
lipid storageGO:001991510.015
negative regulation of behaviorGO:004852160.015
multi organism reproductive processGO:0044703360.015
Worm
neuromast hair cell differentiationGO:0048886120.015
vesicle mediated transportGO:0016192220.015
innate immune responseGO:0045087130.015
maintenance of locationGO:005123540.015
positive regulation of cytokine productionGO:000181920.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.014
guanosine containing compound catabolic processGO:190106920.014
nephron epithelium morphogenesisGO:007208810.014
leukocyte proliferationGO:007066110.014
homeostasis of number of cells within a tissueGO:004887340.014
regulation of protein transportGO:005122330.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
regulation of systemic arterial blood pressureGO:000307310.014
regulation of oxidative stress induced cell deathGO:190320120.014
regulation of protein localization to nucleusGO:190018020.014
regulation of transporter activityGO:003240920.014
Mouse
neural precursor cell proliferationGO:0061351200.014
cellular protein complex disassemblyGO:004362410.014
positive regulation of neuron projection developmentGO:001097690.014
organic substance transportGO:0071702580.014
positive regulation of secretionGO:005104710.014
primary neural tube formationGO:001402010.014
developmental programmed cell deathGO:001062340.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
positive regulation of multicellular organismal processGO:0051240520.013
heterocycle biosynthetic processGO:00181302150.013
macromolecular complex disassemblyGO:003298410.013
secondary metabolic processGO:001974830.013
membrane fusionGO:006102520.013
glial cell migrationGO:000834730.013
regulation of intracellular protein transportGO:003315730.013
regulation of axonogenesisGO:0050770320.013
golgi organizationGO:000703010.013
establishment of synaptic vesicle localizationGO:009748010.013
visual perceptionGO:0007601170.013
post embryonic organ developmentGO:004856940.013
organic acid metabolic processGO:0006082310.013
central nervous system projection neuron axonogenesisGO:0021952150.013
tube morphogenesisGO:00352393490.013
spermatid differentiationGO:004851520.013
regulation of purine nucleotide catabolic processGO:003312120.013
anterior lateral line system developmentGO:004889890.013
anterior posterior axon guidanceGO:003356450.013
protein dephosphorylationGO:000647030.013
phosphorus metabolic processGO:00067931090.013
macromolecule localizationGO:0033036540.013
embryo development ending in birth or egg hatchingGO:00097922710.013
Zebrafish
camera type eye developmentGO:00430102220.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.013
skeletal muscle fiber developmentGO:0048741350.012
vesicle organizationGO:001605060.012
regulation of cell substrate adhesionGO:001081010.012
synapse organizationGO:0050808210.012
anion transmembrane transportGO:0098656120.012
negative regulation of cytokine productionGO:000181810.012
lamellipodium organizationGO:009758110.012
odontogenesis of dentin containing toothGO:004247510.012
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.012
atp catabolic processGO:000620040.012
regulation of biosynthetic processGO:00098892500.012
phagocytosis engulfmentGO:000691110.012
cell cycle g2 m phase transitionGO:004483940.012
apoptotic processGO:00069151160.012
regulation of epidermis developmentGO:004568220.012
lytic vacuole organizationGO:008017110.012
auditory receptor cell differentiationGO:0042491150.012
regulation of neural precursor cell proliferationGO:200017730.012
anatomical structure homeostasisGO:0060249360.012
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.012
determination of left right symmetryGO:00073681790.012
Worm
convergent extensionGO:00600261180.012
regulation of nervous system developmentGO:0051960900.012
locomotor rhythmGO:004547530.012
striated muscle cell developmentGO:00550021080.012
glomerulus developmentGO:0032835270.011
regulation of multicellular organismal developmentGO:20000262230.011
reproductionGO:0000003400.011
Worm
lamellipodium assemblyGO:003003210.011
protein modification processGO:00362111000.011
membrane hyperpolarizationGO:006008110.011
carbohydrate derivative biosynthetic processGO:1901137430.011
aromatic compound biosynthetic processGO:00194382170.011
single organism behaviorGO:0044708240.011
epithelial tube morphogenesisGO:00605621480.011
protein localization to nucleusGO:003450430.011
glutamate receptor signaling pathwayGO:000721510.011
nucleocytoplasmic transportGO:000691340.011
regulation of signal transductionGO:00099662250.011
sequestering of calcium ionGO:005120830.011
regulation of protein targetingGO:190353320.011
regulation of synaptic vesicle transportGO:190280310.011
rna export from nucleusGO:000640510.011
negative chemotaxisGO:005091910.011
entrainment of circadian clockGO:000964920.011
regulation of cellular protein catabolic processGO:190336210.011
localization of cellGO:00516742440.011
apoptotic process involved in developmentGO:190274220.011
calcium ion transportGO:0006816180.011
Zebrafish Mouse Worm
ubiquitin dependent protein catabolic processGO:000651130.011
central nervous system neuron differentiationGO:0021953740.011
tube closureGO:006060610.011
detection of light stimulusGO:0009583120.011
membrane repolarizationGO:008600920.010
Mouse
cellular aromatic compound metabolic processGO:00067252950.010
gtp catabolic processGO:000618420.010
positive regulation of canonical wnt signaling pathwayGO:009026340.010
negative regulation of multi organism processGO:004390130.010
regulation of stem cell differentiationGO:200073640.010
oocyte anterior posterior axis specificationGO:000731440.010
multicellular organismal reproductive processGO:0048609350.010
Worm
sensory perception of light stimulusGO:0050953190.010
protein homooligomerizationGO:005126030.010
phosphate containing compound metabolic processGO:00067961080.010
response to axon injuryGO:0048678140.010
nucleoside monophosphate catabolic processGO:000912540.010
response to glucocorticoidGO:005138410.010
regulation of protein ubiquitinationGO:003139630.010
fat soluble vitamin biosynthetic processGO:004236220.010
protein targeting to nucleusGO:004474430.010
cell matrix adhesionGO:000716040.010

cacna1da disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
auditory system diseaseDOID:274200.134
nervous system diseaseDOID:86300.134
disease of anatomical entityDOID:700.134
nonsyndromic deafnessDOID:005056300.134
sensory system diseaseDOID:005015500.134
autosomal dominant nonsyndromic deafnessDOID:005056400.011