Danio rerio

3 known processes

comta

catechol-O-methyltransferase a

(Aliases: zgc:114157,MGC114157,comt)

comta biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to biotic stimulusGO:0009607970.443
response to copper ionGO:0046688130.316
sulfur compound metabolic processGO:0006790130.302
response to stressGO:00069502630.283
defense responseGO:0006952470.257
estrogen metabolic processGO:000821020.234
regulation of nucleic acid templated transcriptionGO:19035062130.222
response to other organismGO:0051707970.221
response to organic substanceGO:00100331530.218
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.203
defense response to other organismGO:0098542330.196
regulation of epithelial cell proliferationGO:005067830.195
macromolecule glycosylationGO:004341390.195
xenobiotic metabolic processGO:000680540.194
positive regulation of jnk cascadeGO:004633030.186
hepatocyte proliferationGO:007257420.156
response to external biotic stimulusGO:0043207970.153
cellular amine metabolic processGO:004410620.141
periodic partitioningGO:000736510.139
organic acid metabolic processGO:0006082310.139
response to external stimulusGO:00096052640.136
oxoacid metabolic processGO:0043436310.120
response to bacteriumGO:0009617580.120
cellular nitrogen compound metabolic processGO:00346412900.119
regulation of i kappab kinase nf kappab signalingGO:004312240.116
positive regulation of stress activated mapk cascadeGO:003287430.113
epithelial cell proliferation involved in liver morphogenesisGO:007257520.109
amine metabolic processGO:000930820.108
cytoplasmic pattern recognition receptor signaling pathwayGO:000275310.103
positive regulation of epithelial cell proliferationGO:005067910.102
biosynthetic processGO:00090582940.102
defense response to bacteriumGO:0042742220.092
nucleic acid metabolic processGO:00903042440.092
heterocycle metabolic processGO:00464832900.090
osteoclast differentiationGO:003031610.089
multi organism processGO:00517041340.088
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.083
cellular ketone metabolic processGO:0042180110.078
myeloid cell differentiationGO:0030099860.076
regulation of peptidyl tyrosine phosphorylationGO:005073010.076
response to chemicalGO:00422213200.076
positive regulation of erk1 and erk2 cascadeGO:007037420.074
symbiosis encompassing mutualism through parasitismGO:004440340.071
response to inorganic substanceGO:0010035380.069
response to metal ionGO:0010038340.068
organelle assemblyGO:00709251100.068
cell projection assemblyGO:0030031640.068
muscle organ developmentGO:00075171010.068
cellular aromatic compound metabolic processGO:00067252950.067
muscle structure developmentGO:00610611960.066
positive regulation of cellular amino acid metabolic processGO:004576400.065
regulation of anterior head developmentGO:200074220.063
innate immune responseGO:0045087130.063
positive regulation of secretion by cellGO:190353210.063
regulation of cellular amine metabolic processGO:003323800.062
mitochondrion organizationGO:000700540.062
carboxylic acid metabolic processGO:0019752220.061
regulation of erk1 and erk2 cascadeGO:007037240.061
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.060
cellular response to xenobiotic stimulusGO:0071466350.060
regulation of rna biosynthetic processGO:20011412130.059
regulation of transcription dna templatedGO:00063552130.058
regulation of cellular amino acid metabolic processGO:000652100.058
regulation of mitochondrion organizationGO:001082110.057
erk1 and erk2 cascadeGO:007037140.055
cellular macromolecule biosynthetic processGO:00346452240.054
cell cycle g1 s phase transitionGO:004484310.054
organic substance biosynthetic processGO:19015762890.052
positive regulation of immune effector processGO:000269930.052
autophagyGO:000691440.052
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.052
cell deathGO:00082191210.051
regulation of cellular ketone metabolic processGO:001056570.050
macromolecule biosynthetic processGO:00090592270.050
positive regulation of notch signaling pathwayGO:004574730.049
glycosphingolipid biosynthetic processGO:000668810.049
response to uvGO:000941130.048
regulation of gene expressionGO:00104682650.048
cellular biosynthetic processGO:00442492860.047
nitrogen compound metabolic processGO:00068073190.047
cellular component assembly involved in morphogenesisGO:00109271070.047
response to xenobiotic stimulusGO:0009410450.046
protein secretionGO:000930610.045
hepatic duct developmentGO:006101120.045
maintenance of locationGO:005123540.045
thrombocyte differentiationGO:000257440.045
positive regulation of catabolic processGO:000989640.044
transcription dna templatedGO:00063511810.044
cellular macromolecule metabolic processGO:00442603910.044
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.044
cellular response to chemical stimulusGO:00708871570.043
glycoprotein metabolic processGO:0009100230.043
negative regulation of anterior neural cell fate commitment of the neural plateGO:002200110.042
response to carbohydrateGO:000974330.042
larval developmentGO:000216420.042
extrinsic apoptotic signaling pathwayGO:009719130.042
regulation of cytokine productionGO:000181730.041
chemosensory behaviorGO:000763510.041
nucleic acid templated transcriptionGO:00976591810.041
regulation of extrinsic apoptotic signaling pathwayGO:200123630.041
positive regulation of nitrogen compound metabolic processGO:0051173690.040
regulation of establishment of protein localizationGO:007020140.040
single organism localizationGO:19025782250.040
signal transduction in absence of ligandGO:003803410.039
transportGO:00068102200.039
organic cyclic compound metabolic processGO:19013603010.038
cytoskeleton organizationGO:0007010960.038
regulation of nucleobase containing compound metabolic processGO:00192192500.038
neuron projection morphogenesisGO:00488121610.037
purine nucleoside monophosphate catabolic processGO:000912840.037
regulation of cellular biosynthetic processGO:00313262450.037
nephron tubule morphogenesisGO:007207810.037
positive regulation of signalingGO:0023056560.037
hemopoiesisGO:00300971830.037
cell matrix adhesionGO:000716040.037
tissue remodelingGO:004877140.037
nephron epithelium morphogenesisGO:007208810.036
morphogenesis of follicular epitheliumGO:001633310.036
glycoprotein biosynthetic processGO:0009101210.035
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.035
peptide metabolic processGO:000651810.035
regulation of protein modification by small protein conjugation or removalGO:190332030.035
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.034
guanosine containing compound catabolic processGO:190106920.034
bone remodelingGO:004684920.034
neuron projection developmentGO:00311751800.034
agingGO:000756820.034
positive regulation of i kappab kinase nf kappab signalingGO:004312330.034
positive regulation of cellular amine metabolic processGO:003324000.034
antibacterial humoral responseGO:001973120.034
positive regulation of jun kinase activityGO:004350720.033
cellular amino acid metabolic processGO:000652070.033
regulation of response to stimulusGO:00485832690.033
response to cadmium ionGO:0046686140.033
positive regulation of map kinase activityGO:004340630.033
regulation of protein ubiquitinationGO:003139630.033
protein o linked glycosylationGO:000649340.033
gall bladder developmentGO:006101010.033
reflexGO:006000420.033
sister chromatid cohesionGO:000706220.033
ectodermal placode developmentGO:0071696370.032
ganglioside metabolic processGO:000157330.032
monocarboxylic acid biosynthetic processGO:0072330120.032
urogenital system developmentGO:0001655970.032
cell part morphogenesisGO:00329902460.031
organelle organizationGO:00069962270.031
regulation of biological qualityGO:00650082630.031
activation of mapk activityGO:000018730.031
striated muscle tissue developmentGO:00147061100.029
rna localizationGO:000640340.029
regulation of protein catabolic processGO:004217610.028
liver developmentGO:0001889960.028
positive regulation of muscle tissue developmentGO:190186310.028
interspecies interaction between organismsGO:004441940.028
cellular response to molecule of bacterial originGO:007121930.028
regulation of signalingGO:00230512350.028
cell morphogenesisGO:00009022890.028
melanin metabolic processGO:000658220.028
trabecula morphogenesisGO:006138320.028
heterocycle biosynthetic processGO:00181302150.027
negative regulation of cytokine productionGO:000181810.027
regulation of rna metabolic processGO:00512522240.027
regulation of cell communicationGO:00106462320.027
regulation of wnt signaling pathway involved in digestive tract morphogenesisGO:200005620.027
segmentationGO:0035282970.027
sialylationGO:009750340.026
regulation of nucleoside metabolic processGO:000911820.026
nucleobase containing compound metabolic processGO:00061392740.026
cytokinetic processGO:003250620.026
positive regulation of protein complex assemblyGO:003133420.026
macromolecule modificationGO:00434121110.026
positive regulation of cellular catabolic processGO:003133130.025
regulation of bone remodelingGO:004685020.025
protein glycosylationGO:000648690.025
phagocytosisGO:000690930.025
g1 s transition of mitotic cell cycleGO:000008210.025
cell substrate adherens junction assemblyGO:000704510.025
regulation of wnt signaling pathway calcium modulating pathwayGO:000859130.025
neurotransmitter transportGO:000683620.025
rna metabolic processGO:00160702190.025
establishment of localizationGO:00512342440.025
response to corticosteroidGO:003196010.025
negative regulation of defense responseGO:003134820.025
adult behaviorGO:003053420.024
regulation of gtp catabolic processGO:003312420.024
single organism organelle organizationGO:19025891990.024
positive regulation of transportGO:005105020.024
muscle cell differentiationGO:00426921390.024
acylglycerol homeostasisGO:005509020.024
single organism transportGO:00447652060.024
positive regulation of cellular metabolic processGO:0031325940.023
positive regulation of cellular processGO:00485222010.023
i kappab kinase nf kappab signalingGO:000724940.023
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.023
programmed cell deathGO:00125011190.023
cellular protein catabolic processGO:004425740.023
regulation of endothelial cell proliferationGO:000193610.023
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.023
stem cell proliferationGO:007208940.023
positive regulation of cellular component biogenesisGO:004408930.023
regulation of cell activationGO:005086510.023
regulation of macromolecule biosynthetic processGO:00105562250.022
regulation of bindingGO:005109830.022
response to transition metal nanoparticleGO:1990267280.022
cytoskeleton dependent cytokinesisGO:006164030.022
defense response to gram positive bacteriumGO:005083060.022
leukocyte differentiationGO:0002521250.022
regulation of autophagyGO:001050630.022
response to woundingGO:00096111160.022
skeletal system developmentGO:00015011810.021
cellular response to extracellular stimulusGO:003166820.021
cellular component disassemblyGO:002241110.021
mannosylationGO:009750230.021
cytokinesisGO:000091030.021
purine ribonucleoside monophosphate catabolic processGO:000916940.021
actin filament based processGO:0030029640.021
response to dsrnaGO:004333170.021
regulation of nucleotide catabolic processGO:003081120.021
mesenchyme developmentGO:00604851270.021
protein metabolic processGO:00195381830.021
protein modification processGO:00362111000.020
cell projection organizationGO:00300302840.020
smad protein complex assemblyGO:000718310.020
regulation of cell maturationGO:190342910.020
positive regulation of neuron apoptotic processGO:004352510.020
regulation of inflammatory responseGO:005072720.020
regulation of jun kinase activityGO:004350630.020
hematopoietic or lymphoid organ developmentGO:00485341910.020
regulation of hormone levelsGO:0010817210.020
response to virusGO:0009615210.019
regulation of neural precursor cell proliferationGO:200017730.019
rna biosynthetic processGO:00327741810.019
regulation of rac protein signal transductionGO:003502010.019
lipid homeostasisGO:005508830.019
cellular response to nutrient levelsGO:003166920.019
chromosome organization involved in meiosisGO:007019210.019
phagocytosis engulfmentGO:000691110.019
negative regulation of secretionGO:005104820.019
response to nutrientGO:000758430.018
regulation of protein transportGO:005122330.018
cell substrate adhesionGO:003158940.018
proteasomal protein catabolic processGO:001049820.018
neutrophil chemotaxisGO:0030593100.018
gland developmentGO:00487321430.018
stem cell maintenanceGO:001982740.018
anterior head developmentGO:009706520.018
neuron developmentGO:00486662620.018
microtubule depolymerizationGO:000701910.018
positive regulation of biological processGO:00485182530.018
positive regulation of cytoskeleton organizationGO:005149530.018
cellular response to external stimulusGO:007149620.018
chondrocyte intercalation involved in growth plate cartilage morphogenesisGO:000342810.018
gene expressionGO:00104672520.018
production of molecular mediator of immune responseGO:000244020.018
cellular response to endogenous stimulusGO:0071495680.018
cellular response to starvationGO:000926710.017
protein acylationGO:004354330.017
regulation of tissue remodelingGO:003410320.017
cognitionGO:005089010.017
nucleobase containing compound biosynthetic processGO:00346542050.017
muscle tissue developmentGO:00605371100.017
cellular nitrogen compound biosynthetic processGO:00442712180.017
embryonic limb morphogenesisGO:003032620.017
response to oxygen containing compoundGO:1901700550.017
guanosine containing compound metabolic processGO:190106840.017
oocyte developmentGO:0048599140.017
immune effector processGO:0002252230.017
regulation of melanocyte differentiationGO:004563420.017
locomotionGO:00400113130.016
somatic stem cell maintenanceGO:003501910.016
regulation of cell matrix adhesionGO:000195210.016
response to superoxideGO:000030320.016
single organism metabolic processGO:00447102170.016
cellular protein modification processGO:00064641000.016
glycosylationGO:0070085110.016
cellular component morphogenesisGO:00329893360.016
neuroblast proliferationGO:000740520.016
modification dependent protein catabolic processGO:001994130.016
positive regulation of neuron deathGO:190121610.016
aromatic compound biosynthetic processGO:00194382170.016
regulation of biosynthetic processGO:00098892500.016
cell projection morphogenesisGO:00488582440.016
response to monosaccharideGO:003428430.016
morphogenesis of an epithelial foldGO:006057110.016
positive regulation of macromolecule biosynthetic processGO:0010557590.016
tissue regenerationGO:0042246740.016
lipid metabolic processGO:0006629520.015
segment polarity determinationGO:000736710.015
cellular response to stressGO:0033554620.015
triglyceride homeostasisGO:007032820.015
organelle fusionGO:004828430.015
membrane invaginationGO:001032410.015
immune system processGO:00023762410.015
cell morphogenesis involved in neuron differentiationGO:00486671630.015
positive regulation of lymphocyte mediated immunityGO:000270810.015
lamellipodium assemblyGO:003003210.015
proteolysis involved in cellular protein catabolic processGO:005160330.015
mesenchymal cell differentiationGO:0048762870.015
cellular response to biotic stimulusGO:007121630.015
rna modificationGO:000945120.014
oocyte differentiationGO:0009994140.014
cellular amide metabolic processGO:004360340.014
positive regulation of chromosome segregationGO:005198410.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
protein polymerizationGO:005125840.014
regulation of purine nucleotide catabolic processGO:003312120.014
developmental programmed cell deathGO:001062340.014
ear developmentGO:00435831270.014
macromolecule localizationGO:0033036540.014
chemotaxisGO:00069351040.014
cell cycle g2 m phase transitionGO:004483940.014
regulation of mrna processingGO:005068430.014
mediolateral intercalationGO:006003130.014
extracellular matrix assemblyGO:008502910.014
viral processGO:001603210.014
signal transductionGO:00071654550.014
homeostatic processGO:00425921420.014
regulation of gtpase activityGO:004308720.014
cell proliferation in forebrainGO:002184630.014
positive regulation of lipid metabolic processGO:004583410.014
glycosaminoglycan biosynthetic processGO:000602480.014
anterior posterior pattern specificationGO:00099521520.014
nephron morphogenesisGO:007202820.014
male meiosisGO:000714020.014
response to drugGO:004249330.013
sequestering of calcium ionGO:005120830.013
ribonucleoside monophosphate catabolic processGO:000915840.013
microtubule polymerizationGO:004678520.013
negative regulation of mitosisGO:004583930.013
lamellipodium organizationGO:009758110.013
endocardial cushion morphogenesisGO:000320330.013
response to growth factorGO:0070848390.013
positive regulation of nucleoside metabolic processGO:004597910.013
regulation of leukocyte mediated immunityGO:000270310.013
positive regulation of muscle organ developmentGO:004863610.013
somite developmentGO:0061053960.013
optic placode formation involved in camera type eye formationGO:004661930.013
atp synthesis coupled electron transportGO:004277310.013
cytokine metabolic processGO:004210710.013
spinal cord anterior posterior patterningGO:002151210.013
retinal rod cell developmentGO:004654840.013
cellular response to oxygen levelsGO:007145310.013
gtp catabolic processGO:000618420.013
regulation of developmental processGO:00507932470.013
optic placode formationGO:000174340.013
pigment granule organizationGO:004875340.013
peptidyl serine phosphorylationGO:001810510.013
generation of neuronsGO:00486993850.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
behaviorGO:0007610740.013
detection of chemical stimulusGO:000959340.013
activation of jun kinase activityGO:000725720.013
cell morphogenesis involved in differentiationGO:00009041950.013
regulation of phGO:000688530.013
carbohydrate homeostasisGO:003350010.013
response to alkaloidGO:004327920.012
cartilage developmentGO:0051216960.012
cellular response to hypoxiaGO:007145610.012
immunoglobulin productionGO:000237710.012
multicellular organism growthGO:003526440.012
wound healingGO:0042060900.012
regulation of nitrogen compound metabolic processGO:00511712510.012
digestive system developmentGO:00551232890.012
regulation of intracellular signal transductionGO:1902531570.012
regulation of multicellular organismal processGO:00512392770.012
positive regulation of secretionGO:005104710.012
liver morphogenesisGO:007257680.012
development of primary female sexual characteristicsGO:004654540.012
specification of symmetryGO:00097992040.012
sulfur compound biosynthetic processGO:004427290.012
peptidyl serine modificationGO:001820920.012
pole plasm assemblyGO:000731540.012
response to amino acidGO:004320020.012
epithelial cell proliferationGO:0050673170.012
positive regulation of multi organism processGO:004390230.012
regulation of myeloid leukocyte differentiationGO:000276150.012
negative regulation of i kappab kinase nf kappab signalingGO:004312410.012
extracellular structure organizationGO:0043062270.012
gtp metabolic processGO:004603940.012
trabecula formationGO:006034320.012
regulation of behaviorGO:0050795240.012
response to methylmercuryGO:0051597110.012
cell junction maintenanceGO:003433120.012
negative regulation of cell deathGO:0060548600.012
fatty acid oxidationGO:001939510.011
establishment of localization in cellGO:0051649770.011
regulation of skeletal muscle tissue developmentGO:004864140.011
oxidative phosphorylationGO:000611910.011
intracellular signal transductionGO:0035556850.011
gland morphogenesisGO:0022612130.011
keratinocyte differentiationGO:003021600.011
regulation of signal transductionGO:00099662250.011
cellular response to oxygen containing compoundGO:1901701200.011
wnt signaling pathway planar cell polarity pathwayGO:006007140.011
endocardial cushion formationGO:000327220.011
aminoglycan biosynthetic processGO:000602380.011
negative regulation of protein kinase activityGO:000646940.011
protein acetylationGO:000647320.011
spliceosomal complex assemblyGO:000024510.011
microtubule cytoskeleton organization involved in mitosisGO:190285010.011
response to light stimulusGO:0009416460.011
positive regulation of dna metabolic processGO:005105410.011
regulation of protein complex assemblyGO:004325430.011
regulation of cellular metabolic processGO:00313233200.011
phosphate containing compound metabolic processGO:00067961080.011
actin filament polymerizationGO:003004120.011
glycolipid biosynthetic processGO:000924710.011
epithelial cell developmentGO:0002064420.011
positive regulation of nucleotide catabolic processGO:003081310.011
positive regulation of mrna metabolic processGO:190331320.011
morphogenesis of an epitheliumGO:00020093330.011
cell surface receptor signaling pathwayGO:00071663250.011
positive regulation of cytokine productionGO:000181920.011
chordate embryonic developmentGO:00430092710.011
female gonad developmentGO:000858540.011
cytoplasm organizationGO:000702840.011
protein n linked glycosylationGO:000648710.011
negative regulation of kinase activityGO:003367340.011
erythrocyte differentiationGO:0030218540.011
regulation of molecular functionGO:0065009700.011
regulation of protein bindingGO:004339330.011
organonitrogen compound metabolic processGO:1901564740.011
negative regulation of leukocyte differentiationGO:190210610.011
regulation of wnt signaling pathway involved in heart developmentGO:000330720.011
response to molecule of bacterial originGO:0002237140.010
specification of organ identityGO:001009220.010
amide biosynthetic processGO:004360410.010
female meiotic divisionGO:000714320.010
mesenchymal cell proliferationGO:001046310.010
immune system developmentGO:00025201910.010
arterial endothelial cell differentiationGO:006084220.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
protein depolymerizationGO:005126110.010
nuclear importGO:005117030.010
negative regulation of signalingGO:0023057960.010
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathwayGO:002200210.010
regulation of establishment or maintenance of cell polarityGO:003287820.010
negative regulation of cell communicationGO:0010648960.010
apoptotic processGO:00069151160.010
positive regulation of production of molecular mediator of immune responseGO:000270210.010
energy reserve metabolic processGO:000611220.010
negative regulation of multi organism processGO:004390130.010
regulation of primary metabolic processGO:00800903110.010
chemical homeostasisGO:0048878490.010
sensory perception of touchGO:005097520.010

comta disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
disease of cellular proliferationDOID:1456600.014
organ system cancerDOID:005068600.014
cancerDOID:16200.014
gastrointestinal system cancerDOID:311900.014
hematopoietic system diseaseDOID:7400.014
anemiaDOID:235500.014
bone marrow diseaseDOID:496100.014
aplastic anemiaDOID:1244900.014
immune system diseaseDOID:291400.014