Danio rerio

5 known processes

ctsk

cathepsin K

(Aliases: wu:fb08b05,zgc:110367,wu:fa95f03)

ctsk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
collagen metabolic processGO:003296320.822
Human
multicellular organismal macromolecule metabolic processGO:004425920.634
Human
proteolysis involved in cellular protein catabolic processGO:005160330.534
Human
multicellular organismal metabolic processGO:004423620.534
Human
response to abiotic stimulusGO:00096281220.475
signal transductionGO:00071654550.378
protein targeting to nucleusGO:004474430.287
response to chemicalGO:00422213200.285
gene expressionGO:00104672520.284
cell proliferationGO:0008283800.273
response to amino acidGO:004320020.269
regulation of multicellular organismal developmentGO:20000262230.223
response to external stimulusGO:00096052640.189
neuron developmentGO:00486662620.185
response to organic substanceGO:00100331530.184
protein import into nucleusGO:000660630.179
regulation of rna metabolic processGO:00512522240.174
aromatic compound biosynthetic processGO:00194382170.171
tissue regenerationGO:0042246740.168
nuclear importGO:005117030.158
negative regulation of cellular processGO:00485232830.152
response to mechanical stimulusGO:0009612240.150
stem cell maintenanceGO:001982740.149
regulation of epithelial cell proliferationGO:005067830.146
angiogenesisGO:00015251580.144
regulation of anatomical structure morphogenesisGO:00226031300.143
regulation of cell proliferationGO:0042127370.137
negative regulation of biological processGO:00485193040.132
regenerationGO:0031099910.131
cell morphogenesisGO:00009022890.130
regulation of macromolecule metabolic processGO:00602553170.127
cell deathGO:00082191210.125
intestinal cholesterol absorptionGO:003029920.125
immune system processGO:00023762410.124
ameboidal type cell migrationGO:00016671430.119
regulation of rna biosynthetic processGO:20011412130.110
positive regulation of macromolecule metabolic processGO:0010604930.109
cellular component morphogenesisGO:00329893360.103
nuclear transportGO:005116940.100
localization of cellGO:00516742440.099
protein importGO:001703830.097
chordate embryonic developmentGO:00430092710.096
nucleocytoplasmic transportGO:000691340.095
regulation of protein targetingGO:190353320.090
muscle structure developmentGO:00610611960.089
regulation of cell differentiationGO:00455951420.087
positive regulation of biological processGO:00485182530.082
larval developmentGO:000216420.081
blood vessel morphogenesisGO:00485142160.080
morphogenesis of an epitheliumGO:00020093330.080
blood vessel developmentGO:00015682460.079
regulation of biological qualityGO:00650082630.079
Rat
single organism nuclear importGO:190259330.078
cellular response to chemical stimulusGO:00708871570.077
intestinal absorptionGO:005089220.076
cellular protein metabolic processGO:00442671290.076
Human
embryo development ending in birth or egg hatchingGO:00097922710.075
organic acid metabolic processGO:0006082310.074
hematopoietic or lymphoid organ developmentGO:00485341910.073
regulation of nucleic acid templated transcriptionGO:19035062130.073
positive regulation of signal transductionGO:0009967560.073
regulation of bindingGO:005109830.072
regulation of gene expressionGO:00104682650.071
regulation of cell motilityGO:2000145460.070
cellular macromolecule metabolic processGO:00442603910.070
Human
heterocycle biosynthetic processGO:00181302150.069
protein metabolic processGO:00195381830.069
Human
fin regenerationGO:0031101510.065
cellular component biogenesisGO:00440851780.065
cellular component assemblyGO:00226071700.062
regulation of protein localization to nucleusGO:190018020.061
regulation of protein import into nucleusGO:004230620.061
cellular component movementGO:00069283350.061
embryonic organ morphogenesisGO:00485622740.061
regulation of biosynthetic processGO:00098892500.057
regulation of cytoplasmic transportGO:190364940.056
cellular response to organic substanceGO:00713101050.056
generation of neuronsGO:00486993850.056
neuron differentiationGO:00301823530.056
sensory organ developmentGO:00074233930.055
response to antibioticGO:004667710.055
septum transversum developmentGO:000334340.055
cartilage developmentGO:0051216960.054
central nervous system developmentGO:00074173870.054
muscle cell differentiationGO:00426921390.053
protein localization to nucleusGO:003450430.052
regulation of signal transductionGO:00099662250.052
establishment of protein localization to organelleGO:007259440.052
nucleic acid templated transcriptionGO:00976591810.052
cell migration involved in gastrulationGO:0042074790.051
response to stressGO:00069502630.051
protein modification processGO:00362111000.050
tube morphogenesisGO:00352393490.050
regulation of cellular ketone metabolic processGO:001056570.049
positive regulation of cellular processGO:00485222010.048
cell motilityGO:00488702440.048
cell surface receptor signaling pathwayGO:00071663250.048
nitrogen compound metabolic processGO:00068073190.048
myeloid cell differentiationGO:0030099860.048
regulation of chondrocyte differentiationGO:003233010.046
cellular nitrogen compound biosynthetic processGO:00442712180.046
response to woundingGO:00096111160.045
photoreceptor cell fate commitmentGO:004655210.044
regulation of endothelial cell proliferationGO:000193610.044
germ line stem cell maintenanceGO:003071820.043
cell migrationGO:00164772370.043
regulation of response to stimulusGO:00485832690.042
negative regulation of gene expressionGO:0010629650.042
regulation of multicellular organism growthGO:004001440.042
rna metabolic processGO:00160702190.042
regulation of primary metabolic processGO:00800903110.042
head developmentGO:00603223030.042
response to corticosteroidGO:003196010.041
cell projection morphogenesisGO:00488582440.041
transportGO:00068102200.041
response to oxygen containing compoundGO:1901700550.041
mesenchymal cell proliferationGO:001046310.040
regulation of intracellular protein transportGO:003315730.040
skeletal system developmentGO:00015011810.040
determination of heart left right asymmetryGO:00613711170.039
striated muscle cell differentiationGO:00511461290.039
blood circulationGO:0008015870.039
negative regulation of multicellular organismal processGO:0051241690.038
response to monosaccharideGO:003428430.038
regulation of protein complex assemblyGO:004325430.038
notochord developmentGO:0030903540.038
positive regulation of cell communicationGO:0010647560.038
regulation of cellular component movementGO:0051270550.037
immune system developmentGO:00025201910.037
regulation of nucleocytoplasmic transportGO:004682220.037
positive regulation of cell adhesionGO:004578510.036
hemopoiesisGO:00300971830.036
positive regulation of cell deathGO:0010942290.036
cell projection organizationGO:00300302840.036
negative regulation of metabolic processGO:0009892860.036
convergent extension involved in gastrulationGO:0060027710.035
programmed cell deathGO:00125011190.035
convergent extensionGO:00600261180.035
sensory organ morphogenesisGO:00905962000.034
biosynthetic processGO:00090582940.034
regulation of cell deathGO:00109411030.034
muscle cell developmentGO:00550011150.034
protein localizationGO:0008104400.034
glial cell migrationGO:000834730.034
response to hexoseGO:000974630.033
reactive oxygen species metabolic processGO:007259360.033
extrinsic apoptotic signaling pathwayGO:009719130.033
heart processGO:0003015710.032
positive regulation of cellular component biogenesisGO:004408930.032
positive regulation of mesenchymal cell proliferationGO:000205310.032
rna biosynthetic processGO:00327741810.032
membrane fusionGO:006102520.032
regulation of localizationGO:00328791040.032
cell part morphogenesisGO:00329902460.032
regulation of apoptotic processGO:0042981980.031
positive regulation of notch signaling pathwayGO:004574730.031
outflow tract morphogenesisGO:000315110.031
regulation of signalingGO:00230512350.031
positive regulation of signalingGO:0023056560.030
regulation of cell activationGO:005086510.030
apoptotic processGO:00069151160.030
stem cell proliferationGO:007208940.030
extracellular structure organizationGO:0043062270.030
cell morphogenesis involved in neuron differentiationGO:00486671630.029
tissue migrationGO:0090130370.029
response to nutrientGO:000758430.029
transcription dna templatedGO:00063511810.029
multicellular organism growthGO:003526440.029
cellular ketone metabolic processGO:0042180110.029
regulation of vasculature developmentGO:1901342330.029
cellular nitrogen compound metabolic processGO:00346412900.029
regulation of establishment of protein localizationGO:007020140.029
cellular response to external stimulusGO:007149620.029
cell adhesionGO:0007155400.029
response to carbohydrateGO:000974330.028
ubiquitin dependent protein catabolic processGO:000651130.028
establishment of localization in cellGO:0051649770.028
liver developmentGO:0001889960.028
positive regulation of epithelial cell proliferationGO:005067910.028
regulation of cellular component organizationGO:0051128860.027
system processGO:00030081850.027
regulation of embryonic developmentGO:0045995470.027
regulation of neuron differentiationGO:0045664560.027
negative regulation of epithelial cell proliferationGO:005068010.027
response to hormoneGO:0009725480.027
regulation of cell migrationGO:0030334400.027
agingGO:000756820.027
cellular biosynthetic processGO:00442492860.027
nucleobase containing compound metabolic processGO:00061392740.026
negative regulation of cellular metabolic processGO:0031324770.026
cellular component disassemblyGO:002241110.026
response to estrogenGO:0043627270.026
organic substance biosynthetic processGO:19015762890.026
cell cycle arrestGO:000705010.026
regulation of protein transportGO:005122330.025
regulation of stem cell proliferationGO:007209120.025
phagocytosisGO:000690930.025
regulation of macromolecule biosynthetic processGO:00105562250.025
carboxylic acid metabolic processGO:0019752220.024
wound healingGO:0042060900.024
single organism organelle organizationGO:19025891990.024
negative regulation of macromolecule metabolic processGO:0010605760.024
cellular component assembly involved in morphogenesisGO:00109271070.024
establishment of protein localization to plasma membraneGO:009000210.024
segmentationGO:0035282970.023
response to glucoseGO:000974930.023
positive regulation of developmental processGO:0051094500.023
positive regulation of cell substrate adhesionGO:001081110.023
regulation of cytokine productionGO:000181730.022
regulation of nucleobase containing compound metabolic processGO:00192192500.022
cellular response to retinoic acidGO:007130010.022
proteolysisGO:0006508380.022
Human
regulation of locomotionGO:0040012550.022
positive regulation of endothelial cell proliferationGO:000193810.022
circulatory system processGO:0003013870.022
cellular response to extracellular stimulusGO:003166820.022
regulation of cellular macromolecule biosynthetic processGO:20001122220.022
cardiac atrium morphogenesisGO:000320920.022
regulation of i kappab kinase nf kappab signalingGO:004312240.022
regulation of metabolic processGO:00192223590.022
peptide transportGO:001583310.022
negative regulation of protein phosphorylationGO:000193340.022
plasma membrane repairGO:000177820.022
positive regulation of leukocyte differentiationGO:190210710.021
cell morphogenesis involved in differentiationGO:00009041950.021
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.021
i kappab kinase nf kappab signalingGO:000724940.021
cellular protein localizationGO:0034613200.021
positive regulation of cytosolic calcium ion concentrationGO:000720440.021
multi organism processGO:00517041340.021
negative regulation of cell deathGO:0060548600.021
neural retina developmentGO:0003407490.021
collagen fibril organizationGO:003019910.021
muscle tissue developmentGO:00605371100.021
modification dependent protein catabolic processGO:001994130.021
regulation of transcription dna templatedGO:00063552130.021
protein complex biogenesisGO:0070271300.020
neuron projection developmentGO:00311751800.020
cellular protein catabolic processGO:004425740.020
Human
locomotionGO:00400113130.020
positive regulation of response to stimulusGO:0048584800.020
positive regulation of immune effector processGO:000269930.020
striated muscle tissue developmentGO:00147061100.020
epithelium migrationGO:0090132250.019
macromolecule biosynthetic processGO:00090592270.019
muscle organ developmentGO:00075171010.019
positive regulation of wound healingGO:009030310.019
organelle assemblyGO:00709251100.019
single organism metabolic processGO:00447102170.019
Human
response to organic cyclic compoundGO:0014070510.019
response to vitaminGO:003327330.019
lateral inhibitionGO:004633110.019
organelle fusionGO:004828430.019
vasculature developmentGO:00019442780.019
superoxide metabolic processGO:000680120.019
regulation of cellular protein catabolic processGO:190336210.018
regulation of cellular biosynthetic processGO:00313262450.018
response to lipidGO:0033993600.018
intracellular signal transductionGO:0035556850.018
heart formationGO:0060914130.018
bleb assemblyGO:003206010.018
cellular response to endogenous stimulusGO:0071495680.018
regulation of developmental processGO:00507932470.018
positive regulation of transportGO:005105020.018
purine ribonucleoside biosynthetic processGO:004612920.018
regulation of multicellular organismal processGO:00512392770.018
cellular amine metabolic processGO:004410620.018
deathGO:00162651210.018
negative regulation of response to stimulusGO:00485851040.018
brain developmentGO:00074202930.018
urogenital system developmentGO:0001655970.018
digestive system developmentGO:00551232890.018
heterocycle metabolic processGO:00464832900.018
organic cyclic compound biosynthetic processGO:19013622230.017
single organism membrane organizationGO:0044802200.017
taxisGO:00423301090.017
regulation of cell shapeGO:000836010.017
response to ketoneGO:190165410.017
positive regulation of nervous system developmentGO:0051962250.017
response to acid chemicalGO:0001101170.017
regulation of nitrogen compound metabolic processGO:00511712510.017
negative chemotaxisGO:005091910.017
response to drugGO:004249330.017
connective tissue developmentGO:0061448990.017
macromolecule modificationGO:00434121110.017
regulation of programmed cell deathGO:00430671010.017
positive regulation of cellular protein metabolic processGO:0032270220.017
cytosolic calcium ion transportGO:006040130.017
peptidyl serine modificationGO:001820920.017
heart joggingGO:0003146400.017
positive regulation of myeloid cell differentiationGO:004563920.017
regulation of protein metabolic processGO:0051246560.017
release of sequestered calcium ion into cytosolGO:005120930.016
caudal fin morphogenesisGO:003514370.016
nucleobase containing compound biosynthetic processGO:00346542050.016
biological adhesionGO:0022610400.016
cellular response to stressGO:0033554620.016
positive regulation of metabolic processGO:00098931080.016
carbohydrate homeostasisGO:003350010.016
hepaticobiliary system developmentGO:0061008980.016
regulation of blood vessel sizeGO:005088020.016
regulation of mesenchymal cell proliferationGO:001046410.016
pharyngeal system developmentGO:0060037180.016
sequestering of metal ionGO:005123830.016
proteasomal protein catabolic processGO:001049820.015
epithelial tube morphogenesisGO:00605621480.015
organic substance catabolic processGO:1901575280.015
Human
phosphate containing compound metabolic processGO:00067961080.015
regulation of neuron projection developmentGO:0010975400.015
negative regulation of blood circulationGO:190352320.015
nitric oxide metabolic processGO:004620920.015
erk1 and erk2 cascadeGO:007037140.015
regulation of reproductive processGO:200024140.015
negative regulation of intracellular protein transportGO:009031730.015
endodermal cell differentiationGO:0035987190.015
regulation of erk1 and erk2 cascadeGO:007037240.015
cellular protein modification processGO:00064641000.015
glucose homeostasisGO:004259310.015
nephron epithelium morphogenesisGO:007208810.015
response to endogenous stimulusGO:0009719830.015
single organism cellular localizationGO:1902580460.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.014
signal transduction in absence of ligandGO:003803410.014
cartilage morphogenesisGO:0060536130.014
cellular response to nutrient levelsGO:003166920.014
protein heterooligomerizationGO:005129110.014
amine metabolic processGO:000930820.014
regulation of cellular protein metabolic processGO:0032268520.014
locus ceruleus developmentGO:002170330.014
gland developmentGO:00487321430.014
regulation of response to stressGO:0080134360.014
regulation of collagen metabolic processGO:001071220.014
positive regulation of cell activationGO:005086710.014
regulation of dna replicationGO:000627530.014
viral processGO:001603210.013
fat soluble vitamin biosynthetic processGO:004236220.013
negative regulation of signalingGO:0023057960.013
oxidation reduction processGO:0055114410.013
positive regulation of cell differentiationGO:0045597300.013
macromolecule localizationGO:0033036540.013
protein localization to plasma membraneGO:007265910.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.013
epithelial cell migrationGO:0010631250.013
nucleic acid metabolic processGO:00903042440.013
craniofacial suture morphogenesisGO:009709420.013
neuron projection morphogenesisGO:00488121610.013
positive regulation of multicellular organismal processGO:0051240520.013
negative regulation of response to dna damage stimulusGO:200102130.013
regulation of stem cell differentiationGO:200073640.013
sequestering of calcium ionGO:005120830.013
cardiac atrium developmentGO:000323040.012
regulation of muscle contractionGO:000693730.012
multi organism cellular processGO:004476420.012
stem cell differentiationGO:00488631170.012
negative regulation of biosynthetic processGO:0009890550.012
regulation of cell communicationGO:00106462320.012
cellular response to acid chemicalGO:007122980.012
growthGO:00400071740.012
gastrulationGO:00073692080.012
negative regulation of leukocyte differentiationGO:190210610.012
positive regulation of phosphate metabolic processGO:0045937210.012
collagen biosynthetic processGO:003296420.012
extracellular matrix organizationGO:0030198270.012
digestive tract morphogenesisGO:00485462310.012
oxoacid metabolic processGO:0043436310.012
regulation of protein catabolic processGO:004217610.012
cellular macromolecule localizationGO:0070727210.012
organelle organizationGO:00069962270.012
actin polymerization or depolymerizationGO:000815420.012
radial glial cell differentiationGO:006001920.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
reproductive processGO:0022414400.012
g1 s transition of mitotic cell cycleGO:000008210.011
macrophage chemotaxisGO:004824630.011
response to inorganic substanceGO:0010035380.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.011
positive regulation of cellular metabolic processGO:0031325940.011
cellular localizationGO:0051641970.011
single organism biosynthetic processGO:0044711710.011
response to alcoholGO:0097305140.011
negative regulation of dna metabolic processGO:005105340.011
spermatid differentiationGO:004851520.011
nuclear exportGO:005116810.011
regulation of production of molecular mediator of immune responseGO:000270010.011
regulation of synapse assemblyGO:005196330.011
negative regulation of rna biosynthetic processGO:1902679450.011
positive regulation of stem cell proliferationGO:200064810.011
mesenchyme developmentGO:00604851270.011
hindbrain developmentGO:0030902910.011
morphogenesis of a branching epitheliumGO:0061138160.011
morphogenesis of a branching structureGO:0001763210.011
regulation of blood pressureGO:000821710.011
negative regulation of synapse assemblyGO:005196420.011
regulation of tube sizeGO:003515020.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
negative regulation of cell proliferationGO:000828580.010
response to hydrogen peroxideGO:004254230.010
medial fin developmentGO:0033338160.010
phagosome maturationGO:009038210.010
cellular response to oxygen containing compoundGO:1901701200.010
cell activationGO:0001775160.010
regulation of carbohydrate metabolic processGO:000610940.010
macromolecular complex assemblyGO:0065003350.010
cellular response to oxygen levelsGO:007145310.010
leukocyte homeostasisGO:000177620.010
cellular amino acid metabolic processGO:000652070.010

ctsk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
developmental disorder of mental healthDOID:006003700.037
disease of mental healthDOID:15000.037
disease of anatomical entityDOID:700.034
nervous system diseaseDOID:86300.021
immune system diseaseDOID:291400.010