Danio rerio

0 known processes

cul3a

cullin 3a

(Aliases: wu:fc37e01,cul3)

cul3a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.562
positive regulation of biological processGO:00485182530.267
Human
mitotic g2 dna damage checkpointGO:000709530.239
mitotic dna integrity checkpointGO:004477440.221
mitotic dna damage checkpointGO:004477340.210
nuclear divisionGO:0000280230.189
Human
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.183
Human Mouse
single organism reproductive processGO:0044702400.172
Worm
multicellular organism growthGO:003526440.170
meiotic nuclear divisionGO:000712640.170
locomotionGO:00400113130.150
Human
embryo development ending in birth or egg hatchingGO:00097922710.149
Mouse Worm
cellular macromolecule metabolic processGO:00442603910.148
Human Mouse Worm
cell cycleGO:0007049930.145
Human
negative regulation of cellular processGO:00485232830.144
Human
negative regulation of biological processGO:00485193040.142
Human
regulation of multicellular organism growthGO:004001440.134
mitotic g2 m transition checkpointGO:004481830.130
cell cycle processGO:0022402530.130
Human
lipid storageGO:001991510.130
single organism organelle organizationGO:19025891990.125
Human
ubiquitin dependent protein catabolic processGO:000651130.124
Human Mouse
modification dependent macromolecule catabolic processGO:004363230.122
Human Mouse
regulation of metabolic processGO:00192223590.110
Human
response to chemicalGO:00422213200.107
organelle organizationGO:00069962270.100
Human
agingGO:000756820.099
Worm
regulation of protein modification by small protein conjugation or removalGO:190332030.094
mitotic cell cycle processGO:1903047480.083
Human
chromosome organizationGO:0051276310.081
Human
regulation of nucleocytoplasmic transportGO:004682220.081
g2 dna damage checkpointGO:003157230.080
regulation of gene expressionGO:00104682650.074
organelle fissionGO:0048285230.074
Human
positive regulation of cell cycleGO:004578730.074
Human
nuclear transportGO:005116940.070
cognitionGO:005089010.064
establishment of localizationGO:00512342440.063
Human Worm
aromatic compound biosynthetic processGO:00194382170.062
maintenance of locationGO:005123540.061
gene expressionGO:00104672520.061
regulation of protein ubiquitinationGO:003139630.060
organic cyclic compound metabolic processGO:19013603010.060
cellular component morphogenesisGO:00329893360.060
Mouse
negative regulation of protein phosphorylationGO:000193340.059
establishment of protein localization to organelleGO:007259440.058
meiotic cell cycle processGO:190304630.057
regulation of cell shapeGO:000836010.057
multi organism processGO:00517041340.056
Worm
positive regulation of cellular processGO:00485222010.055
Human
regulation of cell cycle phase transitionGO:190198780.055
Human
regulation of multicellular organismal processGO:00512392770.053
nuclear importGO:005117030.052
regulation of developmental processGO:00507932470.051
organic substance biosynthetic processGO:19015762890.051
meiotic chromosome segregationGO:004513230.050
positive regulation of transportGO:005105020.050
macromolecular complex subunit organizationGO:0043933740.050
Human
regulation of biological qualityGO:00650082630.050
modification dependent protein catabolic processGO:001994130.050
Human Mouse
developmental process involved in reproductionGO:0003006270.049
negative regulation of gene expressionGO:0010629650.049
autophagyGO:000691440.049
developmental growthGO:00485891660.048
immune system processGO:00023762410.047
single organism nuclear importGO:190259330.047
dna integrity checkpointGO:003157060.046
proteolysis involved in cellular protein catabolic processGO:005160330.045
Human Mouse
protein localization to nucleusGO:003450430.045
cellular localizationGO:0051641970.044
Human Worm
phagocytosisGO:000690930.043
regulation of signal transductionGO:00099662250.043
Human
stem cell proliferationGO:007208940.043
gastrulationGO:00073692080.043
Mouse
mitotic cell cycle phase transitionGO:004477290.042
Human
growthGO:00400071740.042
synaptic growth at neuromuscular junctionGO:005112420.042
nucleobase containing compound metabolic processGO:00061392740.042
protein modification processGO:00362111000.042
Human
cytoskeleton organizationGO:0007010960.042
Human
response to stressGO:00069502630.041
transcription dna templatedGO:00063511810.041
protein importGO:001703830.041
signal transductionGO:00071654550.040
Human Mouse
regulation of primary metabolic processGO:00800903110.040
Human
neuron developmentGO:00486662620.040
rna localizationGO:000640340.040
cell motilityGO:00488702440.039
Human
response to external biotic stimulusGO:0043207970.039
regulation of establishment of protein localizationGO:007020140.038
single organism transportGO:00447652060.038
Human
cellular protein metabolic processGO:00442671290.038
Human Mouse Worm
extrinsic apoptotic signaling pathwayGO:009719130.038
transportGO:00068102200.038
Human
cellular protein modification processGO:00064641000.038
Human
regulation of cell cycleGO:0051726520.038
Human
nitrogen compound metabolic processGO:00068073190.038
negative regulation of macromolecule metabolic processGO:0010605760.037
nucleic acid metabolic processGO:00903042440.037
cellular component assemblyGO:00226071700.036
Human
protein import into nucleusGO:000660630.036
regulation of protein transportGO:005122330.036
nucleocytoplasmic transportGO:000691340.036
cell surface receptor signaling pathwayGO:00071663250.036
Mouse
heterocycle metabolic processGO:00464832900.036
digestive system developmentGO:00551232890.035
Mouse
macromolecule biosynthetic processGO:00090592270.035
cellular nitrogen compound biosynthetic processGO:00442712180.034
response to uvGO:000941130.034
protein targeting to nucleusGO:004474430.034
mitotic cell cycleGO:0000278640.034
Human
regulation of biosynthetic processGO:00098892500.034
cellular biosynthetic processGO:00442492860.034
regulation of intracellular protein transportGO:003315730.034
skeletal system morphogenesisGO:00487051020.033
negative regulation of metabolic processGO:0009892860.033
negative regulation of mitotic cell cycleGO:0045930110.033
cell cycle g1 s phase transitionGO:004484310.033
regulation of protein import into nucleusGO:004230620.032
reproductionGO:0000003400.032
Worm
regulation of nitrogen compound metabolic processGO:00511712510.032
regulation of cytoplasmic transportGO:190364940.031
somatic muscle developmentGO:000752540.031
cellular component movementGO:00069283350.031
Human
neuron differentiationGO:00301823530.030
regulation of chromosome segregationGO:005198310.030
Human
cellular carbohydrate metabolic processGO:004426240.029
regulation of cell sizeGO:0008361290.029
protein modification by small protein removalGO:007064610.029
cellular component disassemblyGO:002241110.028
rna biosynthetic processGO:00327741810.028
cellular nitrogen compound metabolic processGO:00346412900.028
embryonic organ developmentGO:00485683810.028
defense responseGO:0006952470.028
reproductive processGO:0022414400.027
Worm
sensory organ developmentGO:00074233930.027
negative regulation of cell cycle phase transitionGO:190198850.027
regulation of response to extracellular stimulusGO:003210410.027
regulation of dendrite developmentGO:005077330.027
regulation of protein catabolic processGO:004217610.027
Human
heterocycle biosynthetic processGO:00181302150.027
generation of neuronsGO:00486993850.027
regulation of cell communicationGO:00106462320.027
Human
skeletal system developmentGO:00015011810.026
cellular response to chemical stimulusGO:00708871570.026
muscle structure developmentGO:00610611960.026
g1 s transition of mitotic cell cycleGO:000008210.026
central nervous system developmentGO:00074173870.026
regulation of protein complex assemblyGO:004325430.026
response to biotic stimulusGO:0009607970.025
negative regulation of cell communicationGO:0010648960.025
Human
cytokinesisGO:000091030.025
Human
internal protein amino acid acetylationGO:000647520.025
organic cyclic compound biosynthetic processGO:19013622230.025
hematopoietic or lymphoid organ developmentGO:00485341910.025
regulation of extrinsic apoptotic signaling pathwayGO:200123630.025
regulation of apoptotic processGO:0042981980.025
protein acetylationGO:000647320.024
cellular component biogenesisGO:00440851780.024
Human
response to external stimulusGO:00096052640.024
regulation of macromolecule metabolic processGO:00602553170.024
Human
mitotic nuclear divisionGO:0007067180.024
Human
rna metabolic processGO:00160702190.024
amine metabolic processGO:000930820.024
nucleobase containing compound biosynthetic processGO:00346542050.024
positive regulation of metabolic processGO:00098931080.024
Human
cytoplasm organizationGO:000702840.024
cellular macromolecule biosynthetic processGO:00346452240.024
deathGO:00162651210.023
negative regulation of cell cycle processGO:001094890.023
negative regulation of signal transductionGO:0009968940.023
Human
cellular response to external stimulusGO:007149620.023
protein metabolic processGO:00195381830.023
Human Mouse Worm
cellular aromatic compound metabolic processGO:00067252950.023
single organism metabolic processGO:00447102170.023
Human Worm
macromolecule modificationGO:00434121110.022
Human
regulation of cellular amine metabolic processGO:003323800.022
cellular process involved in reproduction in multicellular organismGO:0022412280.022
regulation of rna biosynthetic processGO:20011412130.022
mesenchymal cell developmentGO:0014031780.021
neuron projection developmentGO:00311751800.021
carboxylic acid metabolic processGO:0019752220.021
spindle assemblyGO:005122520.021
spliceosomal snrnp assemblyGO:000038720.021
ribonucleoside monophosphate catabolic processGO:000915840.021
regulation of dna replicationGO:000627530.021
cell projection morphogenesisGO:00488582440.021
cellular response to hormone stimulusGO:0032870390.021
action potentialGO:0001508190.020
regulation of protein targetingGO:190353320.020
cellular response to nutrient levelsGO:003166920.020
positive regulation of striated muscle tissue developmentGO:004584410.020
regulation of neurological system processGO:003164420.020
tube morphogenesisGO:00352393490.020
Mouse
positive regulation of catabolic processGO:000989640.020
Human
mesenchymal cell differentiationGO:0048762870.020
protein complex disassemblyGO:004324110.020
regulation of response to stimulusGO:00485832690.020
Human
alternative mrna splicing via spliceosomeGO:000038010.020
regulation of programmed cell deathGO:00430671010.020
regulation of cell activationGO:005086510.020
cell morphogenesisGO:00009022890.019
Mouse
response to other organismGO:0051707970.019
cell deathGO:00082191210.019
regulation of meiotic cell cycleGO:005144510.019
muscle tissue developmentGO:00605371100.019
blood vessel developmentGO:00015682460.019
chromosome organization involved in meiosisGO:007019210.019
cellular response to endogenous stimulusGO:0071495680.019
response to drugGO:004249330.019
sexual reproductionGO:0019953360.019
Worm
regulation of alternative mrna splicing via spliceosomeGO:000038110.018
positive regulation of cell activationGO:005086710.018
regulation of autophagyGO:001050630.018
neural crest cell differentiationGO:0014033720.018
biosynthetic processGO:00090582940.018
chordate embryonic developmentGO:00430092710.018
Mouse
peptidyl lysine acetylationGO:001839420.018
regulation of developmental growthGO:0048638380.018
regulation of mitotic cell cycleGO:0007346250.017
Human
response to glucoseGO:000974930.017
negative regulation of kinase activityGO:003367340.017
cellular amine metabolic processGO:004410620.017
regulation of cellular component sizeGO:0032535300.017
regulation of organ growthGO:004662030.017
negative regulation of protein kinase activityGO:000646940.017
cellular response to starvationGO:000926710.017
cellular response to organic substanceGO:00713101050.017
localization of cellGO:00516742440.017
Human
response to corticosteroidGO:003196010.017
myeloid cell differentiationGO:0030099860.017
protein dephosphorylationGO:000647030.017
neurotransmitter secretionGO:000726920.017
positive regulation of cellular catabolic processGO:003133130.017
Human
response to endogenous stimulusGO:0009719830.017
blood vessel morphogenesisGO:00485142160.017
response to oxygen containing compoundGO:1901700550.017
homeostatic processGO:00425921420.017
sister chromatid cohesionGO:000706220.017
meiosis iGO:000712710.017
negative regulation of dna metabolic processGO:005105340.017
single organism localizationGO:19025782250.017
Human
cell proliferationGO:0008283800.016
regulation of cellular ketone metabolic processGO:001056570.016
negative regulation of cytoplasmic transportGO:190365020.016
chemosensory behaviorGO:000763510.016
positive regulation of protein complex assemblyGO:003133420.016
negative regulation of cellular metabolic processGO:0031324770.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.016
regulation of multicellular organismal developmentGO:20000262230.016
negative regulation of dna replicationGO:000815620.016
positive regulation of cellular component biogenesisGO:004408930.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
histone h3 k4 methylationGO:005156820.016
regulation of macromolecule biosynthetic processGO:00105562250.016
protein acylationGO:004354330.016
regulation of epithelial cell proliferationGO:005067830.016
regulation of cellular metabolic processGO:00313233200.016
Human
negative regulation of cell cycleGO:0045786140.016
mitochondrion organizationGO:000700540.016
response to nutrientGO:000758430.016
small molecule metabolic processGO:0044281770.016
regulation of production of molecular mediator of immune responseGO:000270010.016
positive regulation of gene expressionGO:0010628710.016
regulation of signalingGO:00230512350.015
Human
programmed cell deathGO:00125011190.015
oocyte anterior posterior axis specificationGO:000731440.015
positive regulation of apoptotic signaling pathwayGO:200123510.015
heart developmentGO:00075073130.015
hatchingGO:003518840.015
regulation of rna metabolic processGO:00512522240.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
enzyme linked receptor protein signaling pathwayGO:00071671060.015
organism emergence from protective structureGO:007168440.015
regulation of reproductive processGO:200024140.015
cellular response to extracellular stimulusGO:003166820.015
mitotic sister chromatid segregationGO:000007060.015
Human
transmission of nerve impulseGO:0019226190.015
regulation of cell proliferationGO:0042127370.015
regulation of cellular biosynthetic processGO:00313262450.015
meiotic spindle organizationGO:000021210.015
cell migrationGO:00164772370.015
Human
mitotic cell cycle checkpointGO:000709350.015
cellular ketone metabolic processGO:0042180110.015
internal peptidyl lysine acetylationGO:001839320.014
cell part morphogenesisGO:00329902460.014
cell morphogenesis involved in differentiationGO:00009041950.014
Mouse
negative regulation of signalingGO:0023057960.014
Human
positive regulation of chromosome organizationGO:200125210.014
Human
cell cycle phase transitionGO:004477090.014
Human
cell substrate adhesionGO:003158940.014
dna templated transcription initiationGO:000635210.014
cell death in response to oxidative stressGO:003647320.014
multicellular organismal reproductive processGO:0048609350.014
atp catabolic processGO:000620040.014
regulation of cellular amino acid metabolic processGO:000652100.014
regulation of response to nutrient levelsGO:003210710.014
regulation of protein localization to nucleusGO:190018020.014
morphogenesis of an epitheliumGO:00020093330.014
regulation of locomotionGO:0040012550.014
viral processGO:001603210.014
multicellular organismal signalingGO:0035637220.014
organic acid metabolic processGO:0006082310.014
cellular amino acid metabolic processGO:000652070.014
chemotaxisGO:00069351040.014
embryonic cranial skeleton morphogenesisGO:0048701900.014
negative regulation of epithelial cell proliferationGO:005068010.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
positive regulation of secretion by cellGO:190353210.013
primary neural tube formationGO:001402010.013
mrna metabolic processGO:0016071200.013
regulation of glial cell differentiationGO:004568540.013
negative regulation of apoptotic processGO:0043066550.013
embryonic organ morphogenesisGO:00485622740.013
leukocyte proliferationGO:007066110.013
phosphate containing compound metabolic processGO:00067961080.013
positive regulation of cellular metabolic processGO:0031325940.013
Human
neuronal action potentialGO:0019228180.013
regulation of dendrite morphogenesisGO:004881430.013
regulation of synapse organizationGO:005080730.013
adherens junction organizationGO:003433240.013
positive regulation of multicellular organismal processGO:0051240520.013
regulation of mrna processingGO:005068430.013
phosphorylationGO:0016310690.013
organonitrogen compound metabolic processGO:1901564740.013
hemopoiesisGO:00300971830.013
stem cell differentiationGO:00488631170.013
behaviorGO:0007610740.013
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.013
response to organic substanceGO:00100331530.013
ameboidal type cell migrationGO:00016671430.013
stem cell developmentGO:0048864820.013
macromolecule localizationGO:0033036540.013
response to hexoseGO:000974630.013
actin polymerization or depolymerizationGO:000815420.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
lymphocyte proliferationGO:004665110.013
positive regulation of map kinase activityGO:004340630.012
regulation of cell deathGO:00109411030.012
macromolecular complex disassemblyGO:003298410.012
gtp catabolic processGO:000618420.012
cell projection organizationGO:00300302840.012
regulation of transcription dna templatedGO:00063552130.012
mononuclear cell proliferationGO:003294310.012
catabolic processGO:0009056320.012
Human Mouse Worm
proteasomal protein catabolic processGO:001049820.012
Human Mouse
neurotransmitter transportGO:000683620.012
negative regulation of synapse assemblyGO:005196420.012
response to abiotic stimulusGO:00096281220.012
neuron remodelingGO:001632210.012
apoptotic processGO:00069151160.012
positive regulation of neural precursor cell proliferationGO:200017910.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
dna templated transcription elongationGO:000635430.012
regulation of metal ion transportGO:001095940.012
striated muscle tissue developmentGO:00147061100.012
microtubule based processGO:0007017600.012
protein stabilizationGO:005082120.012
protein phosphorylationGO:0006468470.012
lateral inhibitionGO:004633110.012
muscle cell migrationGO:001481240.012
secondary metabolic processGO:001974830.012
regulation of cell cycle processGO:0010564200.012
Human
small molecule catabolic processGO:004428230.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
female sex differentiationGO:004666040.012
adult behaviorGO:003053420.011
regulation of bindingGO:005109830.011
phosphorus metabolic processGO:00067931090.011
gtp metabolic processGO:004603940.011
ovulation cycleGO:004269820.011
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.011
innate immune responseGO:0045087130.011
locomotor rhythmGO:004547530.011
regulation of synaptic plasticityGO:004816710.011
regulation of oocyte developmentGO:006028130.011
positive regulation of lymphocyte mediated immunityGO:000270810.011
cellular catabolic processGO:0044248270.011
Human Mouse Worm
negative regulation of protein serine threonine kinase activityGO:007190120.011
regulation of protein metabolic processGO:0051246560.011
Human
oligodendrocyte differentiationGO:0048709230.011
protein polymerizationGO:005125840.011
sleepGO:003043110.011
regulation of cytokine productionGO:000181730.011
cellular response to stressGO:0033554620.011
nucleobase containing compound transportGO:001593120.011
neuron neuron synaptic transmissionGO:000727010.011
negative regulation of cytokine productionGO:000181810.011
regulation of stem cell proliferationGO:007209120.011
cell matrix adhesionGO:000716040.011
rna export from nucleusGO:000640510.011
spermatid differentiationGO:004851520.011
regulation of behaviorGO:0050795240.011
connective tissue developmentGO:0061448990.011
epithelial cell differentiationGO:00308551160.011
cellular protein catabolic processGO:004425740.011
Human Mouse Worm
positive regulation of programmed cell deathGO:0043068290.011
positive regulation of ras protein signal transductionGO:004657910.011
regulation of growthGO:0040008420.011
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.011
axon ensheathment in central nervous systemGO:003229120.011
stem cell divisionGO:001714510.010
Mouse
neuroblast proliferationGO:000740520.010
regulation of cellular component organizationGO:0051128860.010
Human
ovulation cycle processGO:002260220.010
production of molecular mediator of immune responseGO:000244020.010
multi organism reproductive processGO:0044703360.010
Worm
transcription from rna polymerase ii promoterGO:0006366800.010
negative regulation of map kinase activityGO:004340720.010
endosomal transportGO:001619720.010
proteolysisGO:0006508380.010
Human Mouse
negative regulation of mitotic cell cycle phase transitionGO:190199150.010
stem cell maintenanceGO:001982740.010
carbohydrate biosynthetic processGO:001605110.010
positive regulation of chromosome segregationGO:005198410.010
Human
taxisGO:00423301090.010
positive regulation of stem cell proliferationGO:200064810.010
germ cell developmentGO:0007281220.010
positive regulation of cytoskeleton organizationGO:005149530.010
positive regulation of developmental processGO:0051094500.010
rna transportGO:005065820.010
signal transduction in absence of ligandGO:003803410.010
cell substrate junction assemblyGO:000704420.010
negative regulation of defense responseGO:003134820.010
developmental maturationGO:0021700340.010
positive regulation of translationGO:004572710.010
neuromuscular synaptic transmissionGO:000727420.010
negative regulation of mitosisGO:004583930.010
negative regulation of leukocyte differentiationGO:190210610.010

cul3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.092
nervous system diseaseDOID:86300.022
cancerDOID:16200.019
disease of cellular proliferationDOID:1456600.019
organ system cancerDOID:005068600.016
musculoskeletal system diseaseDOID:1700.011
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011