Danio rerio

0 known processes

dlst

dihydrolipoamide S-succinyltransferase

(Aliases: cb60,wu:fc39d01)

dlst biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.802
Worm
embryo development ending in birth or egg hatchingGO:00097922710.623
Worm
pyruvate metabolic processGO:000609010.466
mitochondrial atp synthesis coupled electron transportGO:004277510.406
coenzyme biosynthetic processGO:000910820.356
atp synthesis coupled electron transportGO:004277310.353
organic acid catabolic processGO:001605430.317
agingGO:000756820.285
carboxylic acid catabolic processGO:004639530.268
electron transport chainGO:002290020.264
cellular respirationGO:004533330.237
thioester biosynthetic processGO:003538410.207
nucleobase containing compound metabolic processGO:00061392740.190
regionalizationGO:00030022740.173
oxidative phosphorylationGO:000611910.158
single organism metabolic processGO:00447102170.153
Yeast
developmental growthGO:00485891660.149
multicellular organism growthGO:003526440.148
mitochondrion organizationGO:000700540.145
Yeast
establishment of localizationGO:00512342440.144
Worm
immune system developmentGO:00025201910.133
stem cell proliferationGO:007208940.129
branched chain amino acid metabolic processGO:000908110.128
cellular macromolecule metabolic processGO:00442603910.128
maintenance of locationGO:005123540.127
small molecule catabolic processGO:004428230.125
regulation of multicellular organism growthGO:004001440.115
mitochondrion morphogenesisGO:007058420.111
gene expressionGO:00104672520.105
cellular component disassemblyGO:002241110.102
mitochondrial electron transport nadh to ubiquinoneGO:000612010.100
cellular biosynthetic processGO:00442492860.099
cellular component movementGO:00069283350.098
single organism localizationGO:19025782250.098
cellular amino acid metabolic processGO:000652070.094
ion transmembrane transportGO:0034220910.092
oxidation reduction processGO:0055114410.088
positive regulation of developmental processGO:0051094500.087
spermatid developmentGO:000728620.086
muscle structure developmentGO:00610611960.083
organic acid metabolic processGO:0006082310.082
Yeast
positive regulation of cellular processGO:00485222010.081
nitrogen compound metabolic processGO:00068073190.080
biosynthetic processGO:00090582940.079
heart developmentGO:00075073130.078
digestive tract morphogenesisGO:00485462310.073
growthGO:00400071740.070
response to external stimulusGO:00096052640.068
morphogenesis of an epitheliumGO:00020093330.068
spermatid differentiationGO:004851520.067
myotube differentiationGO:0014902450.065
heterocycle metabolic processGO:00464832900.065
phagocytosisGO:000690930.064
aromatic compound biosynthetic processGO:00194382170.063
organelle organizationGO:00069962270.062
Yeast
respiratory electron transport chainGO:002290420.062
regulation of biological qualityGO:00650082630.061
localization of cellGO:00516742440.060
oxoacid metabolic processGO:0043436310.060
Yeast
monocarboxylic acid catabolic processGO:007232930.060
hydrogen peroxide metabolic processGO:004274320.059
negative regulation of kinase activityGO:003367340.057
organic cyclic compound metabolic processGO:19013603010.056
positive regulation of biological processGO:00485182530.056
organonitrogen compound metabolic processGO:1901564740.056
response to stressGO:00069502630.055
brain developmentGO:00074202930.055
carboxylic acid metabolic processGO:0019752220.054
Yeast
blood vessel morphogenesisGO:00485142160.054
protein complex disassemblyGO:004324110.054
cell proliferationGO:0008283800.053
organic substance biosynthetic processGO:19015762890.052
organic cyclic compound biosynthetic processGO:19013622230.051
sulfur compound biosynthetic processGO:004427290.049
regenerationGO:0031099910.049
carbohydrate derivative metabolic processGO:1901135610.049
cellular nitrogen compound metabolic processGO:00346412900.048
chordate embryonic developmentGO:00430092710.048
regulation of developmental processGO:00507932470.047
phosphate containing compound metabolic processGO:00067961080.047
somatic muscle developmentGO:000752540.047
germ cell developmentGO:0007281220.046
lipid storageGO:001991510.045
locomotionGO:00400113130.045
Worm
macromolecular complex disassemblyGO:003298410.044
lipid catabolic processGO:001604240.044
determination of left right symmetryGO:00073681790.044
acetyl coa metabolic processGO:000608410.044
regulation of multicellular organismal processGO:00512392770.044
striated muscle cell differentiationGO:00511461290.043
neuroblast proliferationGO:000740520.043
gtp metabolic processGO:004603940.042
regulation of organ growthGO:004662030.042
dicarboxylic acid metabolic processGO:004364810.042
Yeast
regulation of nitrogen compound metabolic processGO:00511712510.042
digestive system developmentGO:00551232890.041
purine ribonucleoside triphosphate biosynthetic processGO:000920620.040
cellular nitrogen compound biosynthetic processGO:00442712180.039
digestive tract developmentGO:00485652650.039
regulation of endopeptidase activityGO:0052548230.039
septum transversum developmentGO:000334340.038
alpha amino acid metabolic processGO:190160530.037
protein polymerizationGO:005125840.036
regulation of cell communicationGO:00106462320.036
regulation of cellular amine metabolic processGO:003323800.036
membrane invaginationGO:001032410.035
phagocytosis engulfmentGO:000691110.035
regulation of neural precursor cell proliferationGO:200017730.035
muscle cell differentiationGO:00426921390.035
blood vessel developmentGO:00015682460.035
small molecule metabolic processGO:0044281770.035
Yeast
positive regulation of multicellular organismal processGO:0051240520.034
endocytosisGO:0006897160.034
Worm
response to chemicalGO:00422213200.033
single organism organelle organizationGO:19025891990.033
embryonic heart tube developmentGO:00350501330.032
regulation of dendrite developmentGO:005077330.032
cell migrationGO:00164772370.032
cellular amine metabolic processGO:004410620.032
purine nucleoside triphosphate biosynthetic processGO:000914520.032
embryonic organ developmentGO:00485683810.031
multi organism processGO:00517041340.031
cellular aromatic compound metabolic processGO:00067252950.031
heart loopingGO:0001947940.031
purine containing compound metabolic processGO:0072521290.031
protein modification processGO:00362111000.031
amine metabolic processGO:000930820.031
signal transductionGO:00071654550.031
regulation of nucleobase containing compound metabolic processGO:00192192500.030
adherens junction organizationGO:003433240.030
monovalent inorganic cation transportGO:0015672420.030
regulation of stem cell proliferationGO:007209120.029
somite developmentGO:0061053960.029
macromolecular complex subunit organizationGO:0043933740.029
transmembrane transportGO:00550851200.029
zymogen activationGO:003163830.029
regulation of nucleoside metabolic processGO:000911820.028
somitogenesisGO:0001756870.028
cellular protein metabolic processGO:00442671290.028
acyl coa biosynthetic processGO:007161610.027
regulation of membrane potentialGO:0042391230.027
inorganic cation transmembrane transportGO:0098662500.027
single organism transportGO:00447652060.027
tube morphogenesisGO:00352393490.026
regulation of cellular ketone metabolic processGO:001056570.026
cofactor biosynthetic processGO:0051188100.026
cellular component morphogenesisGO:00329893360.026
regulation of signal transductionGO:00099662250.026
positive regulation of metabolic processGO:00098931080.026
epithelial tube morphogenesisGO:00605621480.026
nucleic acid transportGO:005065720.025
regulation of cell shapeGO:000836010.025
mitochondrial transportGO:000683920.025
response to organic substanceGO:00100331530.025
cellular amino acid biosynthetic processGO:000865220.025
muscle cell developmentGO:00550011150.025
guanosine containing compound catabolic processGO:190106920.025
organonitrogen compound biosynthetic processGO:1901566470.025
striated muscle cell developmentGO:00550021080.024
meiotic nuclear divisionGO:000712640.024
gastrulationGO:00073692080.024
regulation of fatty acid beta oxidationGO:003199810.024
cell surface receptor signaling pathwayGO:00071663250.024
cellular catabolic processGO:0044248270.024
hematopoietic or lymphoid organ developmentGO:00485341910.023
gtp catabolic processGO:000618420.023
positive regulation of gtp catabolic processGO:003312610.023
cellular component assemblyGO:00226071700.023
cognitionGO:005089010.023
synaptic growth at neuromuscular junctionGO:005112420.023
macromolecule biosynthetic processGO:00090592270.023
regulation of macromolecule metabolic processGO:00602553170.023
hemopoiesisGO:00300971830.023
transportGO:00068102200.023
Worm
regulation of primary metabolic processGO:00800903110.023
apoptotic processGO:00069151160.022
positive regulation of cellular catabolic processGO:003133130.022
epithelial cell morphogenesisGO:000338220.022
cellular lipid catabolic processGO:004424230.022
single organism biosynthetic processGO:0044711710.022
wound healingGO:0042060900.022
cellular localizationGO:0051641970.022
macromolecule modificationGO:00434121110.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
regulation of metabolic processGO:00192223590.022
head developmentGO:00603223030.022
vesicle mediated transportGO:0016192220.022
Worm
energy derivation by oxidation of organic compoundsGO:001598050.021
cation transportGO:0006812810.021
embryonic hemopoiesisGO:0035162530.021
embryonic heart tube morphogenesisGO:00031431080.021
phosphorylationGO:0016310690.021
ion transportGO:00068111140.021
negative regulation of cellular processGO:00485232830.021
negative regulation of dna recombinationGO:004591020.020
regulation of stem cell differentiationGO:200073640.020
establishment of protein localization to organelleGO:007259440.020
angiogenesisGO:00015251580.020
regulation of fatty acid metabolic processGO:001921710.020
regulation of lipid catabolic processGO:005099420.020
reactive oxygen species metabolic processGO:007259360.019
gene silencing by rnaGO:003104740.019
protein metabolic processGO:00195381830.019
rna export from nucleusGO:000640510.019
positive regulation of glucose importGO:004632610.019
peptidyl serine modificationGO:001820920.019
positive regulation of catabolic processGO:000989640.019
circadian sleep wake cycle sleepGO:005080210.019
actin filament based movementGO:003004810.019
regulation of epithelial cell proliferationGO:005067830.019
cell deathGO:00082191210.019
multicellular organismal metabolic processGO:004423620.018
establishment of localization in cellGO:0051649770.018
nucleic acid metabolic processGO:00903042440.018
vasculature developmentGO:00019442780.018
regulation of peptidase activityGO:0052547230.018
positive regulation of transportGO:005105020.018
response to woundingGO:00096111160.018
cellular process involved in reproduction in multicellular organismGO:0022412280.018
regulation of mrna processingGO:005068430.018
regulation of synaptic plasticityGO:004816710.018
regulation of gtpase activityGO:004308720.018
protein depolymerizationGO:005126110.018
determination of bilateral symmetryGO:00098552040.018
regulation of neurogenesisGO:0050767870.018
reactive nitrogen species metabolic processGO:200105700.018
segmentationGO:0035282970.018
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315470.018
cell motilityGO:00488702440.017
fatty acid oxidationGO:001939510.017
reproductionGO:0000003400.017
Worm
regulation of myotube differentiationGO:001083020.017
protein localization to plasma membraneGO:007265910.017
positive regulation of stem cell proliferationGO:200064810.017
cellular response to organic substanceGO:00713101050.017
cellular protein complex disassemblyGO:004362410.017
circadian sleep wake cycle processGO:002241020.017
positive regulation of nucleoside metabolic processGO:004597910.017
negative regulation of neural precursor cell proliferationGO:200017810.017
generation of neuronsGO:00486993850.017
positive regulation of cellular amine metabolic processGO:003324000.017
negative regulation of cell communicationGO:0010648960.017
regulation of cellular amino acid metabolic processGO:000652100.017
regulation of cardiac muscle tissue developmentGO:005502410.017
regulation of dna templated transcription in response to stressGO:004362000.016
syncytium formationGO:0006949120.016
regulation of response to stimulusGO:00485832690.016
cellular component biogenesisGO:00440851780.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
purine nucleotide metabolic processGO:0006163270.016
cellular macromolecule biosynthetic processGO:00346452240.016
organic substance catabolic processGO:1901575280.016
mitotic dna damage checkpointGO:004477340.016
cellular carbohydrate metabolic processGO:004426240.016
cellular response to chemical stimulusGO:00708871570.016
negative regulation of protein kinase activityGO:000646940.016
anterior posterior pattern specificationGO:00099521520.016
specification of symmetryGO:00097992040.016
cell morphogenesisGO:00009022890.016
sexual reproductionGO:0019953360.016
guanosine containing compound metabolic processGO:190106840.016
nucleoside phosphate metabolic processGO:0006753280.016
p38mapk cascadeGO:003806610.016
neurotransmitter transportGO:000683620.016
nucleobase containing small molecule metabolic processGO:0055086320.015
ribose phosphate metabolic processGO:0019693270.015
multicellular organismal reproductive processGO:0048609350.015
cellular protein modification processGO:00064641000.015
convergent extension involved in gastrulationGO:0060027710.015
regulation of cellular component organizationGO:0051128860.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.015
digestive tract mesoderm developmentGO:000750210.015
fatty acid transportGO:001590810.015
nucleotide metabolic processGO:0009117280.015
peptidyl threonine phosphorylationGO:001810710.015
cell substrate adhesionGO:003158940.015
regulation of cellular protein metabolic processGO:0032268520.015
proteolysis involved in cellular protein catabolic processGO:005160330.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.015
nuclear transportGO:005116940.015
inorganic ion transmembrane transportGO:0098660570.015
regulation of purine nucleotide catabolic processGO:003312120.014
ribonucleoside metabolic processGO:0009119110.014
plasma membrane repairGO:000177820.014
phosphorus metabolic processGO:00067931090.014
rna metabolic processGO:00160702190.014
protein localization to nucleusGO:003450430.014
transcription dna templatedGO:00063511810.014
organophosphate biosynthetic processGO:0090407230.014
regulation of signalingGO:00230512350.014
protein importGO:001703830.014
liver developmentGO:0001889960.014
glial cell migrationGO:000834730.014
eye developmentGO:00016542770.014
carbohydrate derivative biosynthetic processGO:1901137430.014
regulation of synapse assemblyGO:005196330.014
organelle assemblyGO:00709251100.014
dorsal ventral pattern formationGO:00099531250.014
negative regulation of multicellular organismal processGO:0051241690.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
regulation of cell developmentGO:00602841000.014
determination of heart left right asymmetryGO:00613711170.014
nucleoside triphosphate biosynthetic processGO:000914220.014
positive regulation of neural precursor cell proliferationGO:200017910.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
purine ribonucleoside metabolic processGO:0046128100.013
thioester metabolic processGO:003538310.013
cellular ketone metabolic processGO:0042180110.013
peptidyl serine phosphorylationGO:001810510.013
positive regulation of cysteine type endopeptidase activityGO:2001056100.013
lipid oxidationGO:003444010.013
regulation of mrna catabolic processGO:006101330.013
negative regulation of biological processGO:00485193040.013
cellular component assembly involved in morphogenesisGO:00109271070.013
skeletal system developmentGO:00015011810.013
regulation of gtp catabolic processGO:003312420.013
immune system processGO:00023762410.013
generation of precursor metabolites and energyGO:000609150.013
positive regulation of ras gtpase activityGO:003232010.013
fin developmentGO:0033333770.013
regulation of establishment of protein localizationGO:007020140.013
oogenesisGO:0048477140.013
regulation of mrna 3 end processingGO:003144010.013
nucleoside biosynthetic processGO:000916320.013
sleepGO:003043110.013
carbohydrate biosynthetic processGO:001605110.013
neuron differentiationGO:00301823530.013
regulation of developmental growthGO:0048638380.013
regulation of protein depolymerizationGO:190187910.012
appendage developmentGO:0048736800.012
mesenchymal cell proliferationGO:001046310.012
meiotic cell cycle processGO:190304630.012
response to drugGO:004249330.012
regulation of nervous system developmentGO:0051960900.012
response to nutrientGO:000758430.012
proteolysisGO:0006508380.012
fatty acid beta oxidationGO:000663510.012
regulation of cell substrate adhesionGO:001081010.012
regulation of striated muscle contractionGO:000694220.012
positive regulation of gtpase activityGO:004354710.012
regulation of phosphorus metabolic processGO:0051174430.012
proepicardium developmentGO:000334240.012
cellular component maintenanceGO:004395430.012
regulation of neurological system processGO:003164420.012
retina development in camera type eyeGO:00600411460.012
establishment of rna localizationGO:005123630.012
cytoskeleton organizationGO:0007010960.012
ribonucleoside triphosphate biosynthetic processGO:000920120.012
cation transmembrane transportGO:0098655650.012
regulation of intracellular protein transportGO:003315730.012
regulation of circadian rhythmGO:004275240.012
actin cytoskeleton organizationGO:0030036630.012
system processGO:00030081850.012
catabolic processGO:0009056320.012
positive regulation of hydrolase activityGO:0051345130.012
nucleobase containing compound biosynthetic processGO:00346542050.012
regulation of gene expressionGO:00104682650.012
purine nucleoside monophosphate catabolic processGO:000912840.012
peptidyl threonine modificationGO:001821010.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
adult behaviorGO:003053420.011
regulation of rho protein signal transductionGO:003502320.011
multicellular organism reproductionGO:0032504350.011
embryonic cranial skeleton morphogenesisGO:0048701900.011
ribonucleoside monophosphate catabolic processGO:000915840.011
negative regulation of epithelial cell proliferationGO:005068010.011
regulation of synapse organizationGO:005080730.011
macromolecular complex assemblyGO:0065003350.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
negative regulation of cytokine productionGO:000181810.011
positive regulation of protein kinase b signalingGO:005189710.011
purine ribonucleotide metabolic processGO:0009150270.011
tissue regenerationGO:0042246740.011
intracellular signal transductionGO:0035556850.011
regulation of fatty acid oxidationGO:004632010.011
neurotransmitter secretionGO:000726920.011
regulation of molecular functionGO:0065009700.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
meiosis iGO:000712710.011
atp metabolic processGO:004603450.011
positive regulation of cell adhesionGO:004578510.011
polyol metabolic processGO:001975110.011
protein acetylationGO:000647320.011
regulation of sodium ion transportGO:000202820.011
retina morphogenesis in camera type eyeGO:0060042790.010
response to vitaminGO:003327330.010
heterocycle catabolic processGO:0046700150.010
regulation of multicellular organismal developmentGO:20000262230.010
hydrogen ion transmembrane transportGO:190260060.010
regulation of behaviorGO:0050795240.010
nitric oxide metabolic processGO:004620920.010
notochord developmentGO:0030903540.010
organophosphate metabolic processGO:0019637370.010
embryonic organ morphogenesisGO:00485622740.010
cellular response to oxygen levelsGO:007145310.010
negative regulation of synapse assemblyGO:005196420.010
long chain fatty acid transportGO:001590910.010
cell cycleGO:0007049930.010
central nervous system developmentGO:00074173870.010
regulation of protein targetingGO:190353320.010
developmental process involved in reproductionGO:0003006270.010

dlst disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.133
disease of metabolismDOID:001466700.085
nervous system diseaseDOID:86300.068
inherited metabolic disorderDOID:65500.065
mitochondrial metabolism diseaseDOID:70000.065
cardiovascular system diseaseDOID:128700.027
amino acid metabolic disorderDOID:925200.026
organ system cancerDOID:005068600.026
disease of cellular proliferationDOID:1456600.026
cancerDOID:16200.026
charcot marie tooth diseaseDOID:1059500.021
neuromuscular diseaseDOID:44000.021
neuropathyDOID:87000.021
musculoskeletal system diseaseDOID:1700.016
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011