Danio rerio

0 known processes

dnmt5

DNA (cytosine-5-)-methyltransferase 5

(Aliases: wu:fc08a10,zgc:136325,MGC136325,dnmt3-2)

dnmt5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna methylation on cytosineGO:003277630.498
Human Zebrafish Mouse
nitrogen compound metabolic processGO:00068073190.335
Human Zebrafish Mouse
regulation of cellular metabolic processGO:00313233200.324
Human Zebrafish Mouse
dna metabolic processGO:0006259270.322
Human Zebrafish Mouse
heterocycle metabolic processGO:00464832900.320
Human Zebrafish Mouse
mitotic dna integrity checkpointGO:004477440.320
cellular macromolecule metabolic processGO:00442603910.319
Human Zebrafish Mouse
cell cycleGO:0007049930.311
organic cyclic compound metabolic processGO:19013603010.289
Human Zebrafish Mouse
cellular macromolecule biosynthetic processGO:00346452240.284
Human Mouse
cellular nitrogen compound metabolic processGO:00346412900.276
Human Zebrafish Mouse
biosynthetic processGO:00090582940.267
Human Mouse
meiotic chromosome segregationGO:004513230.267
mitotic cell cycle processGO:1903047480.244
regulation of histone methylationGO:003106030.235
Human Zebrafish
macromolecule biosynthetic processGO:00090592270.213
Human Mouse
histone h3 k9 modificationGO:006164750.211
Human Zebrafish
nucleobase containing compound metabolic processGO:00061392740.209
Human Zebrafish Mouse
regulation of metabolic processGO:00192223590.208
Human Zebrafish Mouse
regulation of macromolecule metabolic processGO:00602553170.208
Human Zebrafish Mouse
regulation of histone h3 k9 methylationGO:005157020.207
Human Zebrafish
photoreceptor cell differentiationGO:0046530550.205
Zebrafish
regulation of biosynthetic processGO:00098892500.198
Human Mouse
regulation of primary metabolic processGO:00800903110.188
Human Zebrafish Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.179
Human Mouse
organelle organizationGO:00069962270.174
Human Zebrafish Mouse
regulation of response to stimulusGO:00485832690.164
cellular aromatic compound metabolic processGO:00067252950.164
Human Zebrafish Mouse
dna methylation or demethylationGO:004472880.151
Human Zebrafish Mouse
regulation of nitrogen compound metabolic processGO:00511712510.151
Human Mouse
negative regulation of cellular processGO:00485232830.149
Human Mouse
larval developmentGO:000216420.146
heterocycle biosynthetic processGO:00181302150.145
Human Mouse
regulation of transcription dna templatedGO:00063552130.139
Human Mouse
histone lysine methylationGO:0034968120.139
Human Zebrafish
nucleic acid metabolic processGO:00903042440.138
Human Zebrafish Mouse
digestive system developmentGO:00551232890.132
Zebrafish
mitotic nuclear divisionGO:0007067180.131
morphogenesis of an epitheliumGO:00020093330.131
protein alkylationGO:0008213130.122
Human Zebrafish
dna alkylationGO:000630580.117
Human Zebrafish Mouse
transcription dna templatedGO:00063511810.116
Human Mouse
meiotic cell cycle processGO:190304630.113
response to organic substanceGO:00100331530.112
Mouse
nucleic acid templated transcriptionGO:00976591810.110
Human Mouse
rna biosynthetic processGO:00327741810.110
Human Mouse
organelle fissionGO:0048285230.109
protein metabolic processGO:00195381830.104
Human Zebrafish
double strand break repairGO:000630230.103
double strand break repair via homologous recombinationGO:000072410.102
regulation of gene expressionGO:00104682650.102
Human Zebrafish Mouse
protein modification processGO:00362111000.101
Human Zebrafish
cellular response to chemical stimulusGO:00708871570.101
Mouse
regulation of dna replicationGO:000627530.100
histone h3 k9 methylationGO:005156750.099
Human Zebrafish
reciprocal dna recombinationGO:003582510.096
exocrine pancreas developmentGO:0031017280.094
Zebrafish
microtubule organizing center organizationGO:003102310.091
gene expressionGO:00104672520.091
Human Zebrafish Mouse
histone h3 k4 methylationGO:005156820.089
Human
aromatic compound biosynthetic processGO:00194382170.087
Human Mouse
response to other organismGO:0051707970.086
meiotic nuclear divisionGO:000712640.085
chromosome organizationGO:0051276310.079
Human Zebrafish Mouse
mitotic dna damage checkpointGO:004477340.078
cell cycle processGO:0022402530.077
regulation of protein import into nucleusGO:004230620.074
organic substance biosynthetic processGO:19015762890.073
Human Mouse
positive regulation of catalytic activityGO:0043085250.073
nucleobase containing compound biosynthetic processGO:00346542050.072
Human Mouse
recombinational repairGO:000072510.070
g2 m transition of mitotic cell cycleGO:000008640.070
regulation of establishment of protein localizationGO:007020140.070
regulation of programmed cell deathGO:00430671010.069
protein complex localizationGO:003150310.069
Mouse
single organism metabolic processGO:00447102170.068
Human Zebrafish
regulation of mitotic cell cycleGO:0007346250.067
regulation of multicellular organism growthGO:004001440.067
cell morphogenesisGO:00009022890.067
embryo development ending in birth or egg hatchingGO:00097922710.066
Zebrafish
regulation of apoptotic processGO:0042981980.064
cell cycle g2 m phase transitionGO:004483940.063
signal transductionGO:00071654550.061
methylationGO:0032259220.061
Human Zebrafish Mouse
response to biotic stimulusGO:0009607970.061
regulation of nucleic acid templated transcriptionGO:19035062130.060
Human Mouse
retina layer formationGO:0010842240.059
Zebrafish
positive regulation of cell cycleGO:004578730.059
single organism organelle organizationGO:19025891990.059
Human Zebrafish Mouse
sensory organ morphogenesisGO:00905962000.059
Zebrafish
multicellular organism growthGO:003526440.058
mitotic cell cycleGO:0000278640.058
regulation of developmental processGO:00507932470.057
regulation of cellular macromolecule biosynthetic processGO:20001122220.056
Human Mouse
negative regulation of biological processGO:00485193040.056
Human Mouse
cellular response to endogenous stimulusGO:0071495680.054
Mouse
cellular respirationGO:004533330.054
cellular component assemblyGO:00226071700.053
neuron differentiationGO:00301823530.053
Zebrafish
specification of axis polarityGO:006500140.053
rna metabolic processGO:00160702190.053
Human Mouse
cellular response to dna damage stimulusGO:0006974240.053
positive regulation of gene expressionGO:0010628710.052
Human
nuclear divisionGO:0000280230.052
pancreas developmentGO:0031016840.052
Zebrafish
regulation of macromolecule biosynthetic processGO:00105562250.052
Human Mouse
chromosome segregationGO:0007059120.051
neuron developmentGO:00486662620.050
Zebrafish
rna localizationGO:000640340.050
establishment of protein localization to organelleGO:007259440.050
positive regulation of biological processGO:00485182530.049
Human
pharyngeal system developmentGO:0060037180.048
Zebrafish
cellular component biogenesisGO:00440851780.048
macromolecular complex subunit organizationGO:0043933740.047
Human Zebrafish Mouse
regulation of protein catabolic processGO:004217610.047
negative regulation of nucleic acid templated transcriptionGO:1903507450.047
Human Mouse
dna modificationGO:000630480.047
Human Zebrafish Mouse
response to amino acidGO:004320020.046
Mouse
eye photoreceptor cell differentiationGO:0001754450.046
Zebrafish
regulation of rna metabolic processGO:00512522240.046
Human Mouse
cellular response to biotic stimulusGO:007121630.046
mitotic sister chromatid segregationGO:000007060.045
regulation of cell deathGO:00109411030.045
cellular biosynthetic processGO:00442492860.045
Human Mouse
generation of neuronsGO:00486993850.045
Zebrafish
regulation of dna metabolic processGO:0051052110.044
signal transduction by p53 class mediatorGO:0072331130.044
sister chromatid segregationGO:000081960.044
retina morphogenesis in camera type eyeGO:0060042790.044
Zebrafish
cellular response to oxygen levelsGO:007145310.043
histone methylationGO:0016571130.043
Human Zebrafish
heart developmentGO:00075073130.043
protein targeting to nucleusGO:004474430.042
negative regulation of histone methylationGO:003106110.041
Human
positive regulation of nucleotide catabolic processGO:003081310.040
regulation of cellular biosynthetic processGO:00313262450.040
Human Mouse
negative regulation of mitosisGO:004583930.040
single organism nuclear importGO:190259330.040
exocrine system developmentGO:0035272280.040
Zebrafish
reciprocal meiotic recombinationGO:000713110.040
regulation of bindingGO:005109830.039
negative regulation of dna replicationGO:000815620.039
negative regulation of apoptotic processGO:0043066550.039
regulation of rna biosynthetic processGO:20011412130.037
Human Mouse
macromolecular complex assemblyGO:0065003350.037
microtubule based processGO:0007017600.037
stem cell maintenanceGO:001982740.037
transcription from rna polymerase ii promoterGO:0006366800.037
Human Mouse
female gonad developmentGO:000858540.036
cellular response to stressGO:0033554620.036
response to abiotic stimulusGO:00096281220.036
regulation of catalytic activityGO:0050790550.036
intracellular mrna localizationGO:000829810.036
positive regulation of cellular processGO:00485222010.035
Human
cellular nitrogen compound biosynthetic processGO:00442712180.035
Human Mouse
negative regulation of metabolic processGO:0009892860.035
Human Mouse
cell projection morphogenesisGO:00488582440.035
regulation of meiotic cell cycleGO:005144510.034
carboxylic acid metabolic processGO:0019752220.034
response to uvGO:000941130.034
response to stressGO:00069502630.034
cell part morphogenesisGO:00329902460.034
response to radiationGO:0009314510.034
regulation of biological qualityGO:00650082630.033
eye morphogenesisGO:00485921440.033
Zebrafish
protein methylationGO:0006479130.033
Human Zebrafish
cellular response to organic substanceGO:00713101050.033
Mouse
organic cyclic compound biosynthetic processGO:19013622230.032
Human Mouse
protein localization to nucleusGO:003450430.031
response to alkaloidGO:004327920.031
atp catabolic processGO:000620040.031
multicellular organismal reproductive processGO:0048609350.031
regulation of cellular ketone metabolic processGO:001056570.031
response to chemicalGO:00422213200.031
Mouse
negative regulation of cellular metabolic processGO:0031324770.031
Human Mouse
intrinsic apoptotic signaling pathwayGO:0097193200.030
programmed cell deathGO:00125011190.030
apoptotic processGO:00069151160.030
phosphorylationGO:0016310690.030
regulation of protein complex assemblyGO:004325430.029
regulation of protein targetingGO:190353320.029
spindle assemblyGO:005122520.029
heart morphogenesisGO:00030071560.029
positive regulation of cellular catabolic processGO:003133130.029
g1 s transition of mitotic cell cycleGO:000008210.029
response to external biotic stimulusGO:0043207970.029
camera type eye morphogenesisGO:00485931080.029
Zebrafish
single organism reproductive processGO:0044702400.029
regulation of transcription from rna polymerase ii promoterGO:00063571140.028
Human Mouse
cell projection organizationGO:00300302840.028
microtubule cytoskeleton organization involved in mitosisGO:190285010.028
regulation of molecular functionGO:0065009700.028
cellular protein modification processGO:00064641000.028
Human Zebrafish
ribonucleoside monophosphate catabolic processGO:000915840.028
nuclear importGO:005117030.027
positive regulation of chromatin modificationGO:190331010.027
Human
positive regulation of catabolic processGO:000989640.027
negative regulation of nitrogen compound metabolic processGO:0051172590.027
Human Mouse
negative regulation of nucleobase containing compound metabolic processGO:0045934590.027
Human Mouse
oocyte maturationGO:000155640.026
protein importGO:001703830.026
macromolecule modificationGO:00434121110.026
Human Zebrafish Mouse
cellular component morphogenesisGO:00329893360.026
positive regulation of immune effector processGO:000269930.026
organic acid metabolic processGO:0006082310.025
positive regulation of nucleobase containing compound metabolic processGO:0045935690.025
positive regulation of purine nucleotide catabolic processGO:003312310.025
g2 dna damage checkpointGO:003157230.025
purine nucleoside monophosphate catabolic processGO:000912840.025
determination of heart left right asymmetryGO:00613711170.025
regulation of dna recombinationGO:000001820.025
male meiosisGO:000714020.024
dna methylationGO:000630680.024
Human Zebrafish Mouse
cilium morphogenesisGO:0060271850.024
retina development in camera type eyeGO:00600411460.024
Zebrafish
intracellular signal transductionGO:0035556850.024
macromolecule methylationGO:0043414190.024
Human Zebrafish Mouse
negative regulation of signal transductionGO:0009968940.024
digestive tract developmentGO:00485652650.024
positive regulation of hydrolase activityGO:0051345130.024
regulation of chromatin modificationGO:190330850.023
Human Zebrafish
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.023
immunoglobulin mediated immune responseGO:001606430.023
positive regulation of cell deathGO:0010942290.023
centrosome organizationGO:005129710.023
response to drugGO:004249330.023
homeostatic processGO:00425921420.023
multi organism processGO:00517041340.023
protein import into nucleusGO:000660630.023
somatic cell dna recombinationGO:001644410.023
production of molecular mediator of immune responseGO:000244020.022
negative regulation of biosynthetic processGO:0009890550.022
Human Mouse
maintenance of locationGO:005123540.022
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.022
eye developmentGO:00016542770.022
Zebrafish
regulation of cell cycleGO:0051726520.022
response to oxygen containing compoundGO:1901700550.022
Mouse
amine metabolic processGO:000930820.022
hatchingGO:003518840.021
purine ribonucleoside monophosphate catabolic processGO:000916940.021
neural retina developmentGO:0003407490.021
Zebrafish
eye photoreceptor cell developmentGO:0042462300.021
Zebrafish
regulation of protein bindingGO:004339330.021
regulation of production of molecular mediator of immune responseGO:000270010.021
regulation of cysteine type endopeptidase activityGO:2000116210.021
regulation of protein localization to nucleusGO:190018020.020
mitotic cell cycle phase transitionGO:004477290.020
cellular response to hypoxiaGO:007145610.020
response to endogenous stimulusGO:0009719830.020
Mouse
dna recombinationGO:000631050.020
positive regulation of cellular component biogenesisGO:004408930.020
deathGO:00162651210.019
regulation of nucleoside metabolic processGO:000911820.019
establishment of localizationGO:00512342440.019
mitotic g2 dna damage checkpointGO:000709530.019
regulation of cellular amino acid metabolic processGO:000652100.019
anterior posterior pattern specificationGO:00099521520.019
macromolecule localizationGO:0033036540.019
Mouse
negative regulation of rna metabolic processGO:0051253480.019
Human Mouse
nucleocytoplasmic transportGO:000691340.019
positive regulation of histone modificationGO:003105810.019
Human
negative regulation of dna metabolic processGO:005105340.019
regulation of cell cycle processGO:0010564200.019
regulation of peptidase activityGO:0052547230.019
cellular component assembly involved in morphogenesisGO:00109271070.018
regulation of multicellular organismal processGO:00512392770.018
regulation of multicellular organismal developmentGO:20000262230.018
positive regulation of molecular functionGO:0044093330.018
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.018
Human Mouse
negative regulation of macromolecule metabolic processGO:0010605760.018
Human Mouse
cellular protein metabolic processGO:00442671290.018
Human Zebrafish
response to ionizing radiationGO:001021260.018
regulation of nucleocytoplasmic transportGO:004682220.018
developmental programmed cell deathGO:001062340.018
cellular response to decreased oxygen levelsGO:003629410.018
nuclear transportGO:005116940.018
dna biosynthetic processGO:007189730.018
positive regulation of nitrogen compound metabolic processGO:0051173690.018
translational initiationGO:000641330.017
axis specificationGO:0009798430.017
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.017
b cell activationGO:004211320.017
positive regulation of macromolecule metabolic processGO:0010604930.017
Human
regulation of cell communicationGO:00106462320.017
locomotionGO:00400113130.017
negative regulation of chromatin modificationGO:190330910.017
Human
embryonic organ developmentGO:00485683810.017
b cell mediated immunityGO:001972430.017
regulation of signalingGO:00230512350.017
cell cycle arrestGO:000705010.017
cellular protein catabolic processGO:004425740.017
chordate embryonic developmentGO:00430092710.016
Zebrafish
blood vessel morphogenesisGO:00485142160.016
negative regulation of cytoplasmic transportGO:190365020.016
determination of left right symmetryGO:00073681790.016
dna catabolic processGO:000630810.016
skeletal system developmentGO:00015011810.016
vasculogenesisGO:0001570410.016
negative regulation of transcription dna templatedGO:0045892450.016
Human Mouse
growthGO:00400071740.016
cell cycle g1 s phase transitionGO:004484310.016
meiosis iiGO:000713510.016
apoptotic signaling pathwayGO:0097190230.016
chromosome organization involved in meiosisGO:007019210.016
centrosome cycleGO:000709810.016
positive regulation of cellular metabolic processGO:0031325940.016
Human
regulation of intracellular protein transportGO:003315730.016
single organism localizationGO:19025782250.016
nucleoside monophosphate catabolic processGO:000912540.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
oxoacid metabolic processGO:0043436310.016
positive regulation of dna metabolic processGO:005105410.016
response to cadmium ionGO:0046686140.016
regulation of skeletal muscle tissue developmentGO:004864140.016
angiogenesisGO:00015251580.016
central nervous system developmentGO:00074173870.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
regulation of mitotic cell cycle phase transitionGO:190199080.015
negative regulation of protein phosphorylationGO:000193340.015
positive regulation of metabolic processGO:00098931080.015
Human
negative regulation of nuclear divisionGO:005178430.015
cellular response to radiationGO:007147840.015
regulation of cellular protein metabolic processGO:0032268520.015
Human Zebrafish
sister chromatid cohesionGO:000706220.015
cell proliferationGO:0008283800.015
proteasomal protein catabolic processGO:001049820.015
cellular amine metabolic processGO:004410620.015
cellular response to external stimulusGO:007149620.015
regulation of transporter activityGO:003240920.014
photoreceptor cell developmentGO:0042461400.014
Zebrafish
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.014
positive regulation of cell activationGO:005086710.014
cilium organizationGO:0044782710.014
protein localization to microtubule cytoskeletonGO:007269810.014
cellular macromolecular complex assemblyGO:0034622240.014
regulation of purine nucleotide catabolic processGO:003312120.014
regulation of proteolysisGO:0030162240.014
mitotic cell cycle checkpointGO:000709350.014
negative regulation of cell cycleGO:0045786140.014
spindle assembly involved in mitosisGO:009030710.014
positive regulation of apoptotic processGO:0043065290.014
response to transition metal nanoparticleGO:1990267280.014
negative regulation of programmed cell deathGO:0043069580.014
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233290.014
cellular ketone metabolic processGO:0042180110.014
digestive tract morphogenesisGO:00485462310.014
dorsal ventral pattern formationGO:00099531250.013
positive regulation of programmed cell deathGO:0043068290.013
chromatin modificationGO:0016568210.013
Human Zebrafish Mouse
regulation of cytoplasmic transportGO:190364940.013
tube morphogenesisGO:00352393490.013
germ cell developmentGO:0007281220.013
negative regulation of chromosome organizationGO:200125110.013
Human
immunoglobulin productionGO:000237710.013
regulation of cellular amine metabolic processGO:003323800.013
peptidyl serine phosphorylationGO:001810510.013
cellular process involved in reproduction in multicellular organismGO:0022412280.013
regulation of neural precursor cell proliferationGO:200017730.013
histone h3 k36 methylationGO:001045220.013
single organism biosynthetic processGO:0044711710.013
negative regulation of macromolecule biosynthetic processGO:0010558480.013
Human Mouse
cell deathGO:00082191210.013
cardiac atrium developmentGO:000323040.013
phagocytosisGO:000690930.013
cell cycle phase transitionGO:004477090.013
hepaticobiliary system developmentGO:0061008980.013
cell substrate adhesionGO:003158940.013
organonitrogen compound metabolic processGO:1901564740.013
response to estrogenGO:0043627270.013
female meiotic divisionGO:000714320.013
negative regulation of mitotic cell cycleGO:0045930110.012
stem cell differentiationGO:00488631170.012
protein localizationGO:0008104400.012
Mouse
regulation of protein metabolic processGO:0051246560.012
Human Zebrafish
embryonic organ morphogenesisGO:00485622740.012
neuron projection morphogenesisGO:00488121610.012
response to nitrogen compoundGO:1901698190.012
Mouse
regionalizationGO:00030022740.012
lateral inhibitionGO:004633110.012
mitotic g2 m transition checkpointGO:004481830.012
negative regulation of rna biosynthetic processGO:1902679450.012
Human Mouse
modification dependent macromolecule catabolic processGO:004363230.012
organism emergence from protective structureGO:007168440.012
positive regulation of purine nucleotide metabolic processGO:190054490.012
regulation of protein ubiquitinationGO:003139630.012
negative regulation of cell divisionGO:005178240.012
negative regulation of protein transportGO:005122430.012
positive regulation of nucleoside metabolic processGO:004597910.012
cytokinesisGO:000091030.012
regulation of cellular component organizationGO:0051128860.012
Human Zebrafish
anterior posterior axis specificationGO:0009948200.012
epithelial tube morphogenesisGO:00605621480.011
developmental growthGO:00485891660.011
heart loopingGO:0001947940.011
neuromuscular synaptic transmissionGO:000727420.011
regulation of chromatin organizationGO:190227550.011
Human Zebrafish
negative regulation of gene expressionGO:0010629650.011
Human Mouse
covalent chromatin modificationGO:0016569200.011
Human Zebrafish Mouse
positive regulation of leukocyte mediated immunityGO:000270510.011
response to metal ionGO:0010038340.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
regulation of histone modificationGO:003105650.011
Human Zebrafish
positive regulation of biosynthetic processGO:0009891680.011
gamete generationGO:0007276330.011
neuron projection developmentGO:00311751800.011
peptidyl serine modificationGO:001820920.011
positive regulation of signal transductionGO:0009967560.011
response to amphetamineGO:000197510.011
reproductive processGO:0022414400.010
protein complex assemblyGO:0006461300.010
regulation of organelle assemblyGO:190211540.010
regulation of phosphorus metabolic processGO:0051174430.010
small molecule metabolic processGO:0044281770.010
protein localization to centrosomeGO:007153910.010
sexual reproductionGO:0019953360.010
ovarian follicle developmentGO:000154120.010
regulation of signal transductionGO:00099662250.010
cellular response to molecule of bacterial originGO:007121930.010
positive regulation of rna biosynthetic processGO:1902680570.010
system processGO:00030081850.010

dnmt5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.050
cancerDOID:16200.043
organ system cancerDOID:005068600.043
disease of anatomical entityDOID:700.031
thoracic cancerDOID:509300.022
nervous system diseaseDOID:86300.021
gastrointestinal system cancerDOID:311900.013
large intestine cancerDOID:567200.013
intestinal cancerDOID:1015500.013
breast cancerDOID:161200.012
reproductive organ cancerDOID:19300.010