Danio rerio

13 known processes

frem1a

Fras1 related extracellular matrix 1a

(Aliases: rfl)

frem1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
axonal defasciculationGO:000741420.938
appendage morphogenesisGO:0035107560.887
fin morphogenesisGO:0033334530.861
fin developmentGO:0033333770.858
nucleobase containing compound biosynthetic processGO:00346542050.833
skin developmentGO:0043588540.820
appendage developmentGO:0048736800.719
basement membrane organizationGO:007171150.660
Zebrafish
medial fin developmentGO:0033338160.628
signal transductionGO:00071654550.604
organic cyclic compound biosynthetic processGO:19013622230.593
regulation of cellular metabolic processGO:00313233200.581
cell surface receptor signaling pathwayGO:00071663250.549
medial fin morphogenesisGO:0035141140.546
sensory perception of smellGO:000760820.508
embryonic organ developmentGO:00485683810.507
Zebrafish
regulation of gene expressionGO:00104682650.488
negative regulation of cellular processGO:00485232830.416
nucleic acid templated transcriptionGO:00976591810.416
cellular nitrogen compound metabolic processGO:00346412900.398
regulation of transcription dna templatedGO:00063552130.390
transcription dna templatedGO:00063511810.377
embryonic organ morphogenesisGO:00485622740.376
Zebrafish
cell morphogenesisGO:00009022890.365
regulation of nucleic acid templated transcriptionGO:19035062130.352
cellular component morphogenesisGO:00329893360.341
embryonic medial fin morphogenesisGO:003512260.335
regulation of cellular biosynthetic processGO:00313262450.330
regulation of macromolecule metabolic processGO:00602553170.311
aromatic compound biosynthetic processGO:00194382170.285
regulation of signal transductionGO:00099662250.256
embryo development ending in birth or egg hatchingGO:00097922710.254
Zebrafish Worm
negative regulation of signal transductionGO:0009968940.252
regulation of signalingGO:00230512350.250
embryonic appendage morphogenesisGO:0035113300.246
transcription from rna polymerase ii promoterGO:0006366800.245
tube morphogenesisGO:00352393490.237
cell motilityGO:00488702440.236
regionalizationGO:00030022740.235
heterocycle biosynthetic processGO:00181302150.231
rna biosynthetic processGO:00327741810.212
determination of dorsal ventral asymmetryGO:0048262340.209
anterior posterior pattern specificationGO:00099521520.198
regulation of nucleobase containing compound metabolic processGO:00192192500.195
regulation of macromolecule biosynthetic processGO:00105562250.194
regulation of primary metabolic processGO:00800903110.194
mesoderm formationGO:0001707430.185
regulation of multicellular organismal developmentGO:20000262230.182
cellular component movementGO:00069283350.169
regulation of rna metabolic processGO:00512522240.166
rna metabolic processGO:00160702190.166
biosynthetic processGO:00090582940.162
heterocycle metabolic processGO:00464832900.162
regulation of rna biosynthetic processGO:20011412130.162
regulation of nitrogen compound metabolic processGO:00511712510.160
cellular aromatic compound metabolic processGO:00067252950.156
heart morphogenesisGO:00030071560.156
cell morphogenesis involved in neuron differentiationGO:00486671630.154
caudal fin developmentGO:003333690.152
muscle structure developmentGO:00610611960.152
ameboidal type cell migrationGO:00016671430.150
nucleic acid metabolic processGO:00903042440.149
embryonic limb morphogenesisGO:003032620.147
nitrogen compound metabolic processGO:00068073190.146
wound healingGO:0042060900.146
organic cyclic compound metabolic processGO:19013603010.144
positive regulation of cgmp biosynthetic processGO:003082860.141
negative regulation of biological processGO:00485193040.137
negative regulation of response to stimulusGO:00485851040.130
heart developmentGO:00075073130.125
regulation of biosynthetic processGO:00098892500.123
synaptic growth at neuromuscular junctionGO:005112420.115
regulation of response to stimulusGO:00485832690.111
stem cell developmentGO:0048864820.110
regulation of metabolic processGO:00192223590.108
larval developmentGO:000216420.107
regulation of cellular macromolecule biosynthetic processGO:20001122220.105
mesenchymal cell differentiationGO:0048762870.105
single organism nuclear importGO:190259330.103
negative regulation of signalingGO:0023057960.102
cell substrate adhesionGO:003158940.100
Mouse
segmentationGO:0035282970.099
pectoral fin developmentGO:0033339500.099
embryonic viscerocranium morphogenesisGO:0048703520.098
Zebrafish
meiotic chromosome segregationGO:004513230.098
cellular nitrogen compound biosynthetic processGO:00442712180.095
nephron tubule morphogenesisGO:007207810.092
digestive system developmentGO:00551232890.091
ion transmembrane transportGO:0034220910.090
gene expressionGO:00104672520.085
somatic cell dna recombinationGO:001644410.084
negative regulation of small gtpase mediated signal transductionGO:005105810.083
regulation of protein catabolic processGO:004217610.080
positive regulation of biological processGO:00485182530.078
protein metabolic processGO:00195381830.077
endothelial cell migrationGO:0043542190.077
homeostasis of number of cells within a tissueGO:004887340.077
specification of symmetryGO:00097992040.076
cell part morphogenesisGO:00329902460.075
embryonic skeletal system morphogenesisGO:0048704930.074
Zebrafish
cell migration involved in gastrulationGO:0042074790.073
response to stressGO:00069502630.072
positive regulation of catabolic processGO:000989640.072
caudal fin morphogenesisGO:003514370.071
cellular biosynthetic processGO:00442492860.070
gastrulationGO:00073692080.068
digestive tract developmentGO:00485652650.068
positive regulation of cell adhesionGO:004578510.066
regulation of bindingGO:005109830.066
locomotionGO:00400113130.065
regulation of transcription from rna polymerase ii promoterGO:00063571140.062
enzyme linked receptor protein signaling pathwayGO:00071671060.062
regulation of protein bindingGO:004339330.061
brain developmentGO:00074202930.061
cell migrationGO:00164772370.060
localization of cellGO:00516742440.059
angiogenesisGO:00015251580.059
negative regulation of cell communicationGO:0010648960.058
extracellular matrix organizationGO:0030198270.057
Zebrafish
axis specificationGO:0009798430.057
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.057
cognitionGO:005089010.056
extracellular structure organizationGO:0043062270.056
Zebrafish
regulation of bmp signaling pathwayGO:0030510390.056
vasculature developmentGO:00019442780.055
neuron developmentGO:00486662620.055
inner ear developmentGO:00488391260.054
central nervous system developmentGO:00074173870.053
cellular macromolecule biosynthetic processGO:00346452240.052
eye developmentGO:00016542770.050
intracellular signal transductionGO:0035556850.050
hatchingGO:003518840.050
organic substance biosynthetic processGO:19015762890.050
regulation of rho protein signal transductionGO:003502320.049
regulation of synapse assemblyGO:005196330.049
modification dependent protein catabolic processGO:001994130.048
endosomal transportGO:001619720.047
establishment of localizationGO:00512342440.047
regulation of multicellular organismal processGO:00512392770.047
response to external stimulusGO:00096052640.046
negative regulation of multicellular organismal processGO:0051241690.046
single organism localizationGO:19025782250.046
sensory system developmentGO:0048880760.046
cell proliferationGO:0008283800.045
regulation of biological qualityGO:00650082630.045
dorsal ventral pattern formationGO:00099531250.044
notochord morphogenesisGO:0048570170.044
regulation of protein complex assemblyGO:004325430.044
regulation of establishment of protein localizationGO:007020140.044
bmp signaling pathwayGO:0030509520.043
negative regulation of catabolic processGO:000989530.043
coagulationGO:0050817130.043
regulation of synaptic growth at neuromuscular junctionGO:000858210.043
cellular macromolecule metabolic processGO:00442603910.042
organism emergence from protective structureGO:007168440.042
cell morphogenesis involved in differentiationGO:00009041950.042
pectoral fin morphogenesisGO:0035138290.039
sensory organ morphogenesisGO:00905962000.039
nucleobase containing compound metabolic processGO:00061392740.039
regulation of locomotionGO:0040012550.038
stem cell differentiationGO:00488631170.038
cellular response to organic substanceGO:00713101050.038
nuclear transportGO:005116940.038
lens fiber cell morphogenesisGO:007030930.037
regulation of tube sizeGO:003515020.036
regulation of synapse organizationGO:005080730.036
protein polymerizationGO:005125840.036
somite developmentGO:0061053960.036
cellular potassium ion transportGO:0071804100.036
positive regulation of canonical wnt signaling pathwayGO:009026340.035
eye morphogenesisGO:00485921440.035
stem cell divisionGO:001714510.035
macromolecule biosynthetic processGO:00090592270.035
positive regulation of synapse assemblyGO:005196510.034
negative regulation of gene expressionGO:0010629650.034
tube closureGO:006060610.034
epithelial cell developmentGO:0002064420.033
skin morphogenesisGO:004358970.033
camera type eye developmentGO:00430102220.033
neuron projection developmentGO:00311751800.033
establishment of protein localization to plasma membraneGO:009000210.032
positive regulation of cellular processGO:00485222010.032
embryonic pectoral fin morphogenesisGO:0035118240.032
sequestering of calcium ionGO:005120830.032
mesenchyme developmentGO:00604851270.032
ear morphogenesisGO:0042471640.032
gland developmentGO:00487321430.032
positive regulation of fibroblast growth factor receptor signaling pathwayGO:004574390.032
protein activation cascadeGO:007237660.032
protein importGO:001703830.031
maintenance of locationGO:005123540.031
embryonic heart tube morphogenesisGO:00031431080.031
negative regulation of developmental processGO:0051093650.031
regulation of establishment of protein localization to plasma membraneGO:009000310.031
mesoderm developmentGO:0007498880.030
locomotor rhythmGO:004547530.030
septum transversum developmentGO:000334340.030
cellular protein catabolic processGO:004425740.030
protein localization to plasma membraneGO:007265910.030
proteolysis involved in cellular protein catabolic processGO:005160330.029
neuron projection morphogenesisGO:00488121610.029
taxisGO:00423301090.029
regulation of cellular protein catabolic processGO:190336210.029
embryonic heart tube developmentGO:00350501330.028
muscle attachmentGO:001620390.028
embryonic caudal fin morphogenesisGO:003512430.028
forebrain developmentGO:0030900960.028
regulation of system processGO:0044057400.027
cell projection morphogenesisGO:00488582440.027
central nervous system neuron differentiationGO:0021953740.027
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.027
positive regulation of cellular metabolic processGO:0031325940.026
regulation of transportGO:0051049450.026
sensory perception of chemical stimulusGO:000760630.026
intracellular transportGO:0046907320.026
tissue regenerationGO:0042246740.026
inner ear morphogenesisGO:0042472630.026
otic vesicle formationGO:0030916270.026
morphogenesis of an epitheliumGO:00020093330.026
regulation of nucleocytoplasmic transportGO:004682220.025
negative regulation of axon guidanceGO:190266810.025
lytic vacuole organizationGO:008017110.025
positive regulation of transportGO:005105020.025
regenerationGO:0031099910.025
negative regulation of cellular catabolic processGO:003133030.025
blood vessel developmentGO:00015682460.025
negative regulation of apoptotic processGO:0043066550.025
oocyte axis specificationGO:000730950.025
ras protein signal transductionGO:000726570.024
internal protein amino acid acetylationGO:000647520.024
generation of neuronsGO:00486993850.024
endosome organizationGO:000703220.024
formation of primary germ layerGO:0001704620.023
blood coagulation fibrin clot formationGO:007237830.023
developmental programmed cell deathGO:001062340.023
convergent extensionGO:00600261180.023
actin filament organizationGO:0007015150.023
ventral spinal cord developmentGO:0021517350.023
skeletal system developmentGO:00015011810.023
Zebrafish
proepicardium developmentGO:000334240.023
cell proliferation in dorsal spinal cordGO:001045620.023
viral processGO:001603210.023
single organism transportGO:00447652060.023
regulation of cell substrate adhesionGO:001081010.022
response to chemicalGO:00422213200.022
negative regulation of synapse assemblyGO:005196420.022
small gtpase mediated signal transductionGO:000726480.022
stem cell proliferationGO:007208940.022
multicellular organism growthGO:003526440.022
axon extension involved in axon guidanceGO:0048846100.021
positive regulation of transcription dna templatedGO:0045893570.021
cell fate commitmentGO:0045165990.021
release of sequestered calcium ion into cytosolGO:005120930.021
epithelial cell differentiationGO:00308551160.021
sprouting angiogenesisGO:0002040530.021
superoxide metabolic processGO:000680120.021
canonical wnt signaling pathwayGO:0060070480.021
regulation of wnt signaling pathwayGO:0030111530.021
multi organism cellular processGO:004476420.021
regulation of vitamin metabolic processGO:003065660.021
cell fate commitment involved in formation of primary germ layerGO:0060795260.020
cilium morphogenesisGO:0060271850.020
protein localization to nucleusGO:003450430.020
negative regulation of proteolysisGO:0045861100.020
positive regulation of signal transductionGO:0009967560.020
axonogenesisGO:00074091520.020
negative regulation of calcium dependent cell cell adhesionGO:004658810.020
single organism behaviorGO:0044708240.020
lens development in camera type eyeGO:0002088220.020
apoptotic process involved in developmentGO:190274220.019
ubiquitin dependent protein catabolic processGO:000651130.019
modification dependent macromolecule catabolic processGO:004363230.019
head developmentGO:00603223030.019
renal system developmentGO:0072001940.019
regulation of nervous system developmentGO:0051960900.019
protein import into nucleusGO:000660630.019
melanin metabolic processGO:000658220.019
hematopoietic or lymphoid organ developmentGO:00485341910.019
regulation of catalytic activityGO:0050790550.019
blood circulationGO:0008015870.019
establishment of localization in cellGO:0051649770.019
system processGO:00030081850.019
primary neural tube formationGO:001402010.019
regulation of cellular component movementGO:0051270550.019
cellular localizationGO:0051641970.019
determination of bilateral symmetryGO:00098552040.019
epithelial tube morphogenesisGO:00605621480.019
cell cycle g1 s phase transitionGO:004484310.019
agingGO:000756820.018
post anal tail morphogenesisGO:0036342190.018
negative regulation of cytoplasmic transportGO:190365020.018
branching morphogenesis of an epithelial tubeGO:0048754150.018
ectodermal placode developmentGO:0071696370.018
determination of ventral identityGO:0048264210.018
negative regulation of sequestering of calcium ionGO:005128340.018
mesenchymal cell developmentGO:0014031780.018
heart processGO:0003015710.018
positive regulation of protein polymerizationGO:003227320.018
guanosine containing compound metabolic processGO:190106840.018
nephron epithelium morphogenesisGO:007208810.018
negative regulation of chemotaxisGO:005092240.018
regulation of ion transmembrane transportGO:0034765180.018
nuclear importGO:005117030.018
determination of heart left right asymmetryGO:00613711170.017
chemotaxisGO:00069351040.017
striated muscle tissue developmentGO:00147061100.017
regulation of cellular response to growth factor stimulusGO:0090287350.017
hindbrain developmentGO:0030902910.017
macromolecule catabolic processGO:0009057150.017
trabecula formationGO:006034320.017
negative regulation of ras protein signal transductionGO:004658010.017
regulation of sequestering of calcium ionGO:005128240.017
maternal determination of anterior posterior axis embryoGO:000835840.017
rho protein signal transductionGO:000726650.017
cellular response to growth factor stimulusGO:0071363390.017
meiotic cell cycle processGO:190304630.017
negative regulation of striated muscle tissue developmentGO:004584320.016
regulation of oocyte developmentGO:006028130.016
cartilage developmentGO:0051216960.016
atrial cardiac muscle cell differentiationGO:005501150.016
cranial suture morphogenesisGO:006036310.016
regulation of neurogenesisGO:0050767870.016
hemostasisGO:0007599130.016
dorsal convergenceGO:0060030140.016
negative regulation of axon extension involved in axon guidanceGO:004884310.016
regulation of blood vessel sizeGO:005088020.016
heart loopingGO:0001947940.016
immune system processGO:00023762410.016
regulation of protein localization to nucleusGO:190018020.016
kupffer s vesicle developmentGO:0070121500.016
small molecule catabolic processGO:004428230.016
patterning of blood vesselsGO:0001569150.016
diterpenoid biosynthetic processGO:001610270.016
direct ossificationGO:003607230.016
neuromast developmentGO:0048884460.016
dorsal ventral axis specificationGO:0009950140.016
centrosome organizationGO:005129710.015
positive regulation of reproductive processGO:200024320.015
single organismal cell cell adhesionGO:0016337290.015
negative regulation of endopeptidase activityGO:0010951100.015
regulation of heart contractionGO:0008016320.015
ectodermal placode formationGO:0060788260.015
hard palate developmentGO:006002240.015
axon developmentGO:00615641660.015
sensory organ developmentGO:00074233930.015
negative regulation of metabolic processGO:0009892860.015
behaviorGO:0007610740.015
response to woundingGO:00096111160.015
cellular protein metabolic processGO:00442671290.015
somitogenesisGO:0001756870.015
neural crest cell developmentGO:0014032620.015
cell projection organizationGO:00300302840.015
homeostatic processGO:00425921420.015
regulation of programmed cell deathGO:00430671010.015
establishment of protein localization to organelleGO:007259440.015
small molecule metabolic processGO:0044281770.015
protein targeting to nucleusGO:004474430.014
phosphorylationGO:0016310690.014
monovalent inorganic cation transportGO:0015672420.014
transportGO:00068102200.014
neuron projection guidanceGO:0097485860.014
regulation of cytoplasmic transportGO:190364940.014
positive regulation of nucleobase containing compound metabolic processGO:0045935690.014
otolith developmentGO:0048840320.014
embryonic neurocranium morphogenesisGO:0048702150.014
semicircular canal formationGO:006087640.014
response to fluid shear stressGO:003440520.014
regulation of proteolysisGO:0030162240.014
outflow tract morphogenesisGO:000315110.014
lateral inhibitionGO:004633110.014
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.014
regulation of bone mineralizationGO:003050020.014
signal transduction in absence of ligandGO:003803410.014
regulation of cell shapeGO:000836010.014
otic vesicle developmentGO:0071599420.014
positive regulation of neuron deathGO:190121610.014
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.014
neuroblast proliferationGO:000740520.014
insulin like growth factor receptor signaling pathwayGO:004800940.014
lipoprotein metabolic processGO:004215740.014
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.013
regulation of developmental processGO:00507932470.013
inorganic ion transmembrane transportGO:0098660570.013
extracellular matrix assemblyGO:008502910.013
carbohydrate biosynthetic processGO:001605110.013
circulatory system processGO:0003013870.013
anterior posterior axon guidanceGO:003356450.013
negative regulation of protein complex assemblyGO:003133310.013
blood coagulationGO:0007596120.013
nucleocytoplasmic transportGO:000691340.013
cation transmembrane transportGO:0098655650.013
circadian behaviorGO:004851250.013
extrinsic apoptotic signaling pathwayGO:009719130.013
negative regulation of chromatin modificationGO:190330910.013
protein complex biogenesisGO:0070271300.013
positive regulation of cellular catabolic processGO:003133130.013
vestibular receptor cell developmentGO:006011830.013
response to abiotic stimulusGO:00096281220.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
internal peptidyl lysine acetylationGO:001839320.013
water homeostasisGO:003010440.013
trabecula morphogenesisGO:006138320.013
negative regulation of defense responseGO:003134820.013
single organism metabolic processGO:00447102170.013
blood vessel morphogenesisGO:00485142160.012
alcohol biosynthetic processGO:004616520.012
positive regulation of response to stimulusGO:0048584800.012
regulation of cell differentiationGO:00455951420.012
positive regulation of endothelial cell migrationGO:001059520.012
lens fiber cell developmentGO:007030730.012
positive regulation of developmental processGO:0051094500.012
actin filament polymerizationGO:003004120.012
nephron morphogenesisGO:007202820.012
programmed cell deathGO:00125011190.012
regulation of membrane repolarizationGO:006030610.012
negative regulation of macromolecule metabolic processGO:0010605760.012
positive regulation of multi organism processGO:004390230.012
cytoplasmic transportGO:0016482110.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
regulation of metal ion transportGO:001095940.012
motor neuron axon guidanceGO:0008045230.012
determination of left right asymmetry in diencephalonGO:003546240.012
cellular response to nutrient levelsGO:003166920.012
kidney morphogenesisGO:0060993150.012
renal tubule morphogenesisGO:006133310.012
odontogenesis of dentin containing toothGO:004247510.012
single organism cellular localizationGO:1902580460.012
blood vessel endothelial cell migrationGO:0043534180.012
cellular component maintenanceGO:004395430.012
retinal ganglion cell axon guidanceGO:0031290350.012
skeletal muscle organ developmentGO:0060538780.012
limb developmentGO:006017380.011
regulation of stem cell differentiationGO:200073640.011
regulation of intracellular protein transportGO:003315730.011
convergent extension involved in gastrulationGO:0060027710.011
regulation of cellular ketone metabolic processGO:001056570.011
embryonic hemopoiesisGO:0035162530.011
developmental growthGO:00485891660.011
organ formationGO:0048645170.011
regulation of localizationGO:00328791040.011
negative regulation of programmed cell deathGO:0043069580.011
peptidyl lysine acetylationGO:001839420.011
morphogenesis of a branching structureGO:0001763210.011
regulation of canonical wnt signaling pathwayGO:0060828340.011
lymphocyte proliferationGO:004665110.011
fin regenerationGO:0031101510.011
negative regulation of signal transduction in absence of ligandGO:190109910.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
protein complex assemblyGO:0006461300.011
regulation of cell communicationGO:00106462320.011
optokinetic behaviorGO:000763490.011
regulation of synapse structure and activityGO:005080350.011
neuron differentiationGO:00301823530.011
cellular response to extracellular stimulusGO:003166820.011
multi organism processGO:00517041340.011
interspecies interaction between organismsGO:004441940.011
regulation of protein targetingGO:190353320.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.011
rhombomere 5 developmentGO:002157140.011
transmembrane transportGO:00550851200.011
mononuclear cell proliferationGO:003294310.011
lipid storageGO:001991510.011
negative regulation of heart contractionGO:004582220.010
wnt signaling pathwayGO:0016055800.010
regulation of protein import into nucleusGO:004230620.010
regulation of cell activationGO:005086510.010
response to endogenous stimulusGO:0009719830.010
gtp metabolic processGO:004603940.010
protein catabolic processGO:003016370.010
regulation of transporter activityGO:003240920.010
mesodermal cell migrationGO:0008078120.010
regulation of epithelial to mesenchymal transitionGO:001071730.010
negative regulation of transcription dna templatedGO:0045892450.010
actin polymerization or depolymerizationGO:000815420.010
mucopolysaccharide metabolic processGO:190351020.010
protein homooligomerizationGO:005126030.010

frem1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:005015500.425
retinal diseaseDOID:567900.425
retinal degenerationDOID:846600.425
eye diseaseDOID:561400.425
nervous system diseaseDOID:86300.425
disease of anatomical entityDOID:700.425
eye and adnexa diseaseDOID:149200.425
musculoskeletal system diseaseDOID:1700.017
connective tissue diseaseDOID:6500.015
bone diseaseDOID:008000100.015
bone development diseaseDOID:008000600.013
osteochondrodysplasiaDOID:225600.013
dysostosisDOID:193400.012
disease of metabolismDOID:001466700.012
synostosisDOID:1197100.012
inherited metabolic disorderDOID:65500.011
cardiovascular system diseaseDOID:128700.011