Danio rerio

13 known processes

frem2a

Fras1 related extracellular matrix protein 2a

(Aliases: bla)

frem2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
appendage developmentGO:0048736800.945
appendage morphogenesisGO:0035107560.907
chordate embryonic developmentGO:00430092710.888
fin developmentGO:0033333770.874
embryonic viscerocranium morphogenesisGO:0048703520.860
regulation of multicellular organismal processGO:00512392770.816
embryonic cranial skeleton morphogenesisGO:0048701900.785
fin morphogenesisGO:0033334530.722
cognitionGO:005089010.693
basement membrane organizationGO:007171150.681
embryonic organ developmentGO:00485683810.668
embryo development ending in birth or egg hatchingGO:00097922710.662
embryonic organ morphogenesisGO:00485622740.633
embryonic skeletal system developmentGO:0048706970.608
skeletal system developmentGO:00015011810.591
embryonic skeletal system morphogenesisGO:0048704930.571
endoderm developmentGO:0007492490.530
axonal defasciculationGO:000741420.506
meiotic chromosome segregationGO:004513230.465
skeletal system morphogenesisGO:00487051020.464
cell matrix adhesionGO:000716040.461
regulation of gene expressionGO:00104682650.420
medial fin developmentGO:0033338160.415
determination of dorsal ventral asymmetryGO:0048262340.366
cell motilityGO:00488702440.361
organic cyclic compound metabolic processGO:19013603010.334
organic cyclic compound biosynthetic processGO:19013622230.319
medial fin morphogenesisGO:0035141140.317
digestive tract developmentGO:00485652650.308
pectoral fin developmentGO:0033339500.302
angiogenesisGO:00015251580.292
regulation of signalingGO:00230512350.290
embryonic limb morphogenesisGO:003032620.285
otic placode formationGO:0043049230.282
tube morphogenesisGO:00352393490.266
macromolecule biosynthetic processGO:00090592270.265
larval developmentGO:000216420.259
nucleic acid templated transcriptionGO:00976591810.239
extracellular structure organizationGO:0043062270.222
biosynthetic processGO:00090582940.216
embryonic medial fin morphogenesisGO:003512260.207
rna biosynthetic processGO:00327741810.206
cell migrationGO:00164772370.200
embryonic appendage morphogenesisGO:0035113300.198
signal transductionGO:00071654550.192
odontogenesis of dentin containing toothGO:004247510.185
cellular macromolecule metabolic processGO:00442603910.169
skin developmentGO:0043588540.165
caudal fin developmentGO:003333690.164
rhombomere 5 developmentGO:002157140.164
vasculature developmentGO:00019442780.155
regulation of rna biosynthetic processGO:20011412130.153
extracellular matrix organizationGO:0030198270.149
regionalizationGO:00030022740.149
negative regulation of response to stimulusGO:00485851040.148
regulation of cellular biosynthetic processGO:00313262450.147
cellular response to growth factor stimulusGO:0071363390.146
regulation of calcium dependent cell cell adhesionGO:004658610.145
caudal fin morphogenesisGO:003514370.141
cell substrate adhesionGO:003158940.139
transcription dna templatedGO:00063511810.135
generation of neuronsGO:00486993850.131
skeletal muscle organ developmentGO:0060538780.130
response to woundingGO:00096111160.130
regulation of transcription dna templatedGO:00063552130.129
cellular aromatic compound metabolic processGO:00067252950.128
cellular component maintenanceGO:004395430.125
pectoral fin morphogenesisGO:0035138290.125
regulation of signal transductionGO:00099662250.123
response to stressGO:00069502630.120
synaptic growth at neuromuscular junctionGO:005112420.116
aromatic compound biosynthetic processGO:00194382170.115
heterocycle metabolic processGO:00464832900.114
cell proliferationGO:0008283800.110
regulation of macromolecule biosynthetic processGO:00105562250.108
negative regulation of cellular processGO:00485232830.108
wound healingGO:0042060900.107
dorsal ventral pattern formationGO:00099531250.105
response to external stimulusGO:00096052640.105
nephron tubule morphogenesisGO:007207810.105
transcription from rna polymerase ii promoterGO:0006366800.101
cellular biosynthetic processGO:00442492860.100
positive regulation of cgmp biosynthetic processGO:003082860.099
somitogenesisGO:0001756870.098
negative regulation of multicellular organismal processGO:0051241690.098
enzyme linked receptor protein signaling pathwayGO:00071671060.095
cell morphogenesis involved in neuron differentiationGO:00486671630.095
neuron developmentGO:00486662620.094
spinal cord developmentGO:0021510460.094
nucleobase containing compound biosynthetic processGO:00346542050.093
neural tube patterningGO:0021532330.089
immune system developmentGO:00025201910.089
regenerationGO:0031099910.089
hematopoietic or lymphoid organ developmentGO:00485341910.087
cellular component biogenesisGO:00440851780.087
muscle attachmentGO:001620390.085
nucleic acid metabolic processGO:00903042440.085
rna metabolic processGO:00160702190.079
regulation of nucleic acid templated transcriptionGO:19035062130.079
regulation of protein catabolic processGO:004217610.078
regulation of response to stimulusGO:00485832690.078
apoptotic processGO:00069151160.076
taxisGO:00423301090.075
regulation of locomotionGO:0040012550.075
vestibular receptor cell differentiationGO:006011430.075
regulation of biosynthetic processGO:00098892500.075
negative regulation of cytoplasmic transportGO:190365020.075
negative regulation of calcium dependent cell cell adhesionGO:004658810.075
response to chemicalGO:00422213200.074
positive regulation of catabolic processGO:000989640.073
kupffer s vesicle developmentGO:0070121500.072
embryonic pectoral fin morphogenesisGO:0035118240.072
female meiotic divisionGO:000714320.072
cellular response to organic substanceGO:00713101050.072
somite developmentGO:0061053960.071
urogenital system developmentGO:0001655970.071
inner ear developmentGO:00488391260.071
central nervous system formationGO:002155610.070
muscle organ developmentGO:00075171010.069
septum transversum developmentGO:000334340.067
mesodermal cell differentiationGO:0048333210.065
immune system processGO:00023762410.063
regulation of cellular macromolecule biosynthetic processGO:20001122220.062
skin morphogenesisGO:004358970.062
intracellular signal transductionGO:0035556850.061
response to topologically incorrect proteinGO:003596620.060
cellular response to external stimulusGO:007149620.059
cellular response to nutrient levelsGO:003166920.059
anterior posterior pattern specificationGO:00099521520.059
response to growth factorGO:0070848390.058
myeloid cell differentiationGO:0030099860.057
cellular nitrogen compound metabolic processGO:00346412900.056
cellular component movementGO:00069283350.056
meiotic cell cycle processGO:190304630.056
positive regulation of cell adhesionGO:004578510.055
eye developmentGO:00016542770.054
digestive system developmentGO:00551232890.054
heart loopingGO:0001947940.052
positive regulation of cellular component biogenesisGO:004408930.051
stem cell proliferationGO:007208940.051
axis specificationGO:0009798430.050
negative regulation of striated muscle tissue developmentGO:004584320.050
rostrocaudal neural tube patterningGO:0021903290.050
cell surface receptor signaling pathwayGO:00071663250.050
organism emergence from protective structureGO:007168440.050
cellular component morphogenesisGO:00329893360.049
single organism metabolic processGO:00447102170.049
tissue regenerationGO:0042246740.048
specification of symmetryGO:00097992040.048
cytosolic calcium ion transportGO:006040130.047
negative regulation of biological processGO:00485193040.047
hemopoiesisGO:00300971830.046
lens fiber cell morphogenesisGO:007030930.046
segmentationGO:0035282970.046
embryonic heart tube developmentGO:00350501330.046
brain morphogenesisGO:0048854180.046
heart developmentGO:00075073130.046
nucleobase containing compound metabolic processGO:00061392740.045
gastrulationGO:00073692080.045
notochord developmentGO:0030903540.045
renal system developmentGO:0072001940.045
gland developmentGO:00487321430.044
neuron projection morphogenesisGO:00488121610.044
heterocycle biosynthetic processGO:00181302150.043
camera type eye developmentGO:00430102220.043
locomotionGO:00400113130.043
positive regulation of biological processGO:00485182530.042
endodermal cell differentiationGO:0035987190.041
neurotransmitter secretionGO:000726920.041
regulation of macromolecule metabolic processGO:00602553170.041
muscle structure developmentGO:00610611960.041
otolith developmentGO:0048840320.040
regulation of rho protein signal transductionGO:003502320.040
mononuclear cell proliferationGO:003294310.040
muscle tissue developmentGO:00605371100.039
cilium morphogenesisGO:0060271850.039
localization of cellGO:00516742440.039
modification dependent protein catabolic processGO:001994130.038
regulation of oocyte developmentGO:006028130.038
regulation of cell communicationGO:00106462320.038
immune responseGO:0006955280.037
regulation of protein polymerizationGO:003227120.037
regulation of nitrogen compound metabolic processGO:00511712510.037
regulation of cell differentiationGO:00455951420.037
negative regulation of oocyte developmentGO:006028320.036
small molecule metabolic processGO:0044281770.036
formation of primary germ layerGO:0001704620.035
neuron projection developmentGO:00311751800.035
water homeostasisGO:003010440.035
regulation of tube sizeGO:003515020.034
internal protein amino acid acetylationGO:000647520.034
actin filament polymerizationGO:003004120.033
regulation of multicellular organismal developmentGO:20000262230.033
negative regulation of muscle tissue developmentGO:190186220.033
cell morphogenesis involved in differentiationGO:00009041950.033
protein stabilizationGO:005082120.033
sensory organ developmentGO:00074233930.033
locomotor rhythmGO:004547530.033
central nervous system developmentGO:00074173870.032
regulation of biological qualityGO:00650082630.032
skeletal muscle tissue developmentGO:0007519670.032
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.032
regulation of endodermal cell fate specificationGO:0042663150.032
striated muscle tissue developmentGO:00147061100.032
hard palate developmentGO:006002240.032
regulation of nucleobase containing compound metabolic processGO:00192192500.032
regulation of transcription from rna polymerase ii promoterGO:00063571140.031
sensory organ morphogenesisGO:00905962000.031
camera type eye morphogenesisGO:00485931080.031
blood coagulationGO:0007596120.030
organophosphate biosynthetic processGO:0090407230.030
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.030
regulation of rna metabolic processGO:00512522240.029
regulation of cellular component movementGO:0051270550.029
protein polymerizationGO:005125840.029
multi organism cellular processGO:004476420.029
gene expressionGO:00104672520.029
regulation of protein complex assemblyGO:004325430.029
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.029
sensory perception of smellGO:000760820.029
mesoderm developmentGO:0007498880.029
regulation of neurological system processGO:003164420.028
actin polymerization or depolymerizationGO:000815420.028
regulation of primary metabolic processGO:00800903110.028
kidney developmentGO:0001822920.028
purine ribonucleotide biosynthetic processGO:0009152200.027
macromolecular complex subunit organizationGO:0043933740.027
superoxide metabolic processGO:000680120.027
connective tissue developmentGO:0061448990.027
protein importGO:001703830.027
dorsal ventral axis specificationGO:0009950140.027
regulation of protein bindingGO:004339330.027
cell deathGO:00082191210.026
forebrain developmentGO:0030900960.026
epithelial cell developmentGO:0002064420.026
regulation of developmental processGO:00507932470.026
midbrain developmentGO:0030901280.026
endothelial cell migrationGO:0043542190.026
blood vessel morphogenesisGO:00485142160.026
somatic muscle developmentGO:000752540.026
circadian behaviorGO:004851250.026
regulation of bone remodelingGO:004685020.026
post anal tail morphogenesisGO:0036342190.026
inositol lipid mediated signalingGO:004801720.026
organic substance biosynthetic processGO:19015762890.025
cellular macromolecule biosynthetic processGO:00346452240.025
establishment of localizationGO:00512342440.025
digestive tract morphogenesisGO:00485462310.025
establishment of protein localization to plasma membraneGO:009000210.025
regulation of dendrite developmentGO:005077330.025
positive regulation of epithelial cell migrationGO:001063420.025
vestibular receptor cell developmentGO:006011830.025
neuron differentiationGO:00301823530.025
regulation of neurogenesisGO:0050767870.025
negative regulation of small gtpase mediated signal transductionGO:005105810.025
regulation of cytokine productionGO:000181730.025
regulation of synaptic growth at neuromuscular junctionGO:000858210.024
organ formationGO:0048645170.024
positive regulation of protein complex assemblyGO:003133420.024
ras protein signal transductionGO:000726570.024
positive regulation of protein polymerizationGO:003227320.024
phosphatidylinositol mediated signalingGO:004801520.024
embryonic caudal fin morphogenesisGO:003512430.024
regulation of synapse assemblyGO:005196330.024
spinal cord oligodendrocyte cell fate specificationGO:002153020.024
regulation of cell fate specificationGO:0042659200.024
biological adhesionGO:0022610400.024
positive regulation of fibroblast growth factor receptor signaling pathwayGO:004574390.024
adrenal gland developmentGO:0030325100.023
proepicardium developmentGO:000334240.023
sprouting angiogenesisGO:0002040530.023
convergent extension involved in gastrulationGO:0060027710.023
determination of dorsal identityGO:0048263130.023
b cell activationGO:004211320.023
single organism cell adhesionGO:0098602290.023
transmembrane transportGO:00550851200.023
cell projection morphogenesisGO:00488582440.023
cellular response to extracellular stimulusGO:003166820.023
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.023
regulation of cell migrationGO:0030334400.023
peptidyl threonine phosphorylationGO:001810710.023
negative regulation of wound healingGO:006104510.023
protein localization to plasma membraneGO:007265910.022
phosphate containing compound metabolic processGO:00067961080.022
pharyngeal muscle developmentGO:004328240.022
regulation of cell activationGO:005086510.022
positive regulation of cellular processGO:00485222010.022
cellular response to chemical stimulusGO:00708871570.022
protein acetylationGO:000647320.022
positive regulation of muscle organ developmentGO:004863610.022
regulation of autophagyGO:001050630.022
regulation of establishment of protein localization to plasma membraneGO:009000310.022
oocyte maturationGO:000155640.022
cranial suture morphogenesisGO:006036310.022
regulation of bindingGO:005109830.021
regulation of ion transmembrane transportGO:0034765180.021
blood vessel developmentGO:00015682460.021
positive regulation of synapse assemblyGO:005196510.021
regulation of p38mapk cascadeGO:190074410.021
regulation of establishment of protein localizationGO:007020140.021
porphyrin containing compound metabolic processGO:0006778100.021
dna templated transcription elongationGO:000635430.021
oocyte differentiationGO:0009994140.021
apoptotic process involved in developmentGO:190274220.021
nitrogen compound metabolic processGO:00068073190.021
stem cell maintenanceGO:001982740.021
female meiosis chromosome segregationGO:001632110.021
forebrain regionalizationGO:002187140.021
cellular protein catabolic processGO:004425740.020
cellular component assemblyGO:00226071700.020
pathway restricted smad protein phosphorylationGO:006038910.020
dorsal convergenceGO:0060030140.020
internal peptidyl lysine acetylationGO:001839320.020
regulation of programmed cell deathGO:00430671010.020
b cell differentiationGO:003018310.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.020
trabecula morphogenesisGO:006138320.020
endosomal transportGO:001619720.020
neuroblast proliferationGO:000740520.020
positive regulation of canonical wnt signaling pathwayGO:009026340.020
negative regulation of chromosome organizationGO:200125110.020
phagocytosis engulfmentGO:000691110.020
stem cell differentiationGO:00488631170.020
specification of organ positionGO:001015930.019
hatchingGO:003518840.019
nephron epithelium morphogenesisGO:007208810.019
regulation of reproductive processGO:200024140.019
regulation of cell proliferation involved in tissue homeostasisGO:006078420.019
cell projection organizationGO:00300302840.019
embryonic neurocranium morphogenesisGO:0048702150.019
regulation of blood vessel sizeGO:005088020.019
oogenesisGO:0048477140.019
central nervous system neuron differentiationGO:0021953740.019
protein metabolic processGO:00195381830.019
axonogenesisGO:00074091520.019
small gtpase mediated signal transductionGO:000726480.019
bone remodelingGO:004684920.019
negative regulation of cellular catabolic processGO:003133030.019
ear morphogenesisGO:0042471640.019
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.019
small molecule catabolic processGO:004428230.019
negative regulation of cell communicationGO:0010648960.019
organophosphate metabolic processGO:0019637370.018
mitotic g2 m transition checkpointGO:004481830.018
morphogenesis of an epithelial foldGO:006057110.018
defense response to bacteriumGO:0042742220.018
negative regulation of catabolic processGO:000989530.018
neuromast developmentGO:0048884460.018
determination of heart left right asymmetryGO:00613711170.018
protein complex biogenesisGO:0070271300.018
regulation of embryonic developmentGO:0045995470.018
glial cell differentiationGO:0010001420.018
mesenchyme developmentGO:00604851270.018
positive regulation of transcription dna templatedGO:0045893570.018
single organism reproductive processGO:0044702400.018
release of sequestered calcium ion into cytosolGO:005120930.018
regulation of endothelial cell proliferationGO:000193610.018
proximal distal pattern formationGO:000995410.018
agingGO:000756820.018
positive regulation of mesenchymal cell proliferationGO:000205310.018
multicellular organismal homeostasisGO:0048871290.018
regulation of intracellular protein transportGO:003315730.018
regulation of sterol transportGO:003237130.018
protein localization to nucleusGO:003450430.018
cellular response to endogenous stimulusGO:0071495680.018
ectodermal placode developmentGO:0071696370.018
cartilage developmentGO:0051216960.017
protein import into nucleusGO:000660630.017
eye morphogenesisGO:00485921440.017
regulation of gastrulationGO:0010470240.017
renal tubule morphogenesisGO:006133310.017
notochord morphogenesisGO:0048570170.017
ectodermal placode morphogenesisGO:0071697320.017
positive regulation of transportGO:005105020.017
establishment of localization in cellGO:0051649770.017
growthGO:00400071740.017
regulation of cell fate commitmentGO:0010453220.017
cell morphogenesisGO:00009022890.017
regulation of cellular metabolic processGO:00313233200.017
programmed cell deathGO:00125011190.017
hydrogen peroxide metabolic processGO:004274320.017
determination of bilateral symmetryGO:00098552040.017
positive regulation of lymphocyte mediated immunityGO:000270810.017
behaviorGO:0007610740.017
autophagyGO:000691440.017
peptidyl lysine acetylationGO:001839420.016
mesenchymal cell proliferationGO:001046310.016
single organism localizationGO:19025782250.016
response to endogenous stimulusGO:0009719830.016
positive regulation of dna metabolic processGO:005105410.016
sequestering of calcium ionGO:005120830.016
regulation of mesenchymal cell proliferationGO:001046410.016
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.016
cgmp biosynthetic processGO:000618270.016
lymphocyte proliferationGO:004665110.016
embryonic skeletal joint morphogenesisGO:006027230.016
maintenance of locationGO:005123540.016
multicellular organism growthGO:003526440.016
regulation of extrinsic apoptotic signaling pathwayGO:200123630.016
single organism cellular localizationGO:1902580460.016
regulation of cell motilityGO:2000145460.016
determination of ventral identityGO:0048264210.016
positive regulation of neuron deathGO:190121610.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
meiosis iGO:000712710.016
single organism biosynthetic processGO:0044711710.016
positive regulation of cellular catabolic processGO:003133130.016
regulation of coagulationGO:005081820.015
embryonic heart tube morphogenesisGO:00031431080.015
axon extension involved in axon guidanceGO:0048846100.015
organic substance catabolic processGO:1901575280.015
homeostatic processGO:00425921420.015
hemostasisGO:0007599130.015
epithelial cell migrationGO:0010631250.015
chondrocyte developmentGO:000206340.015
negative regulation of signal transductionGO:0009968940.015
limb developmentGO:006017380.015
ubiquitin dependent protein catabolic processGO:000651130.015
regulation of cellular ketone metabolic processGO:001056570.015
sensory perception of chemical stimulusGO:000760630.015
response to biotic stimulusGO:0009607970.015
axon developmentGO:00615641660.015
trabecula formationGO:006034320.015
retinoic acid metabolic processGO:004257390.015
positive regulation of myeloid cell differentiationGO:004563920.015
cellular response to stressGO:0033554620.015
somite rostral caudal axis specificationGO:003252550.015
phosphatidylinositol 3 kinase signalingGO:001406520.015
protein homooligomerizationGO:005126030.015
single organism nuclear importGO:190259330.015
cellular response to starvationGO:000926710.015
nuclear transportGO:005116940.015
otic vesicle morphogenesisGO:0071600340.014
regulation of angiogenesisGO:0045765260.014
multi organism processGO:00517041340.014
response to fluid shear stressGO:003440520.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
regulation of cell developmentGO:00602841000.014
insulin like growth factor receptor signaling pathwayGO:004800940.014
positive regulation of stem cell proliferationGO:200064810.014
reciprocal meiotic recombinationGO:000713110.014
cell part morphogenesisGO:00329902460.014
osteoclast developmentGO:003603510.014
spemann organizer formation at the embryonic shieldGO:006006320.014
positive regulation of multi organism processGO:004390230.014
regulation of nucleocytoplasmic transportGO:004682220.014
patterning of blood vesselsGO:0001569150.014
regulation of intracellular signal transductionGO:1902531570.014
midbrain hindbrain boundary developmentGO:0030917230.014
craniofacial suture morphogenesisGO:009709420.014
smooth muscle contractionGO:000693920.014
peptidyl threonine modificationGO:001821010.014
kidney morphogenesisGO:0060993150.014
protein acylationGO:004354330.014
regulation of wnt signaling pathway involved in heart developmentGO:000330720.014
modification dependent macromolecule catabolic processGO:004363230.014
g2 dna damage checkpointGO:003157230.014
exocrine system developmentGO:0035272280.014
lens fiber cell developmentGO:007030730.014
blood circulationGO:0008015870.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
catecholamine metabolic processGO:000658420.014
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.014
germ cell developmentGO:0007281220.014
homeostasis of number of cells within a tissueGO:004887340.013
negative regulation of embryonic developmentGO:0045992110.013
single organism transportGO:00447652060.013
response to transition metal nanoparticleGO:1990267280.013
endothelial cell proliferationGO:0001935110.013
catechol containing compound metabolic processGO:000971220.013
phosphorus metabolic processGO:00067931090.013
response to vitaminGO:003327330.013
defense responseGO:0006952470.013
adherens junction organizationGO:003433240.013
transportGO:00068102200.013
regulation of growth rateGO:004000910.013
macromolecule modificationGO:00434121110.013
viral processGO:001603210.013
microtubule cytoskeleton organization involved in mitosisGO:190285010.013
carbohydrate biosynthetic processGO:001605110.013
regulation of wound healingGO:006104120.013
regulation of cgmp biosynthetic processGO:003082660.013
peptidyl serine phosphorylationGO:001810510.013
embryonic axis specificationGO:0000578120.013

frem2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.046
disease of anatomical entityDOID:700.046
musculoskeletal system diseaseDOID:1700.031
bone diseaseDOID:008000100.031
bone development diseaseDOID:008000600.031
connective tissue diseaseDOID:6500.031
nervous system diseaseDOID:86300.024
disease of cellular proliferationDOID:1456600.020
cancerDOID:16200.020
disease of metabolismDOID:001466700.018
inherited metabolic disorderDOID:65500.018
lysosomal storage diseaseDOID:321100.018
organ system cancerDOID:005068600.015
sensory system diseaseDOID:005015500.013