Danio rerio

47 known processes

gmnn

geminin, DNA replication inhibitor

(Aliases: sb:cb254,zgc:66217)

gmnn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of macromolecule biosynthetic processGO:00105562250.549
Human Mouse Fly
cellular biosynthetic processGO:00442492860.529
Human Mouse Fly
regulation of cellular biosynthetic processGO:00313262450.398
Human Mouse Fly
cellular component morphogenesisGO:00329893360.369
larval developmentGO:000216420.338
cellular protein catabolic processGO:004425740.329
regulation of nitrogen compound metabolic processGO:00511712510.326
Human Mouse Fly
modification dependent protein catabolic processGO:001994130.318
regulation of gene expressionGO:00104682650.299
Human Mouse
mitotic dna integrity checkpointGO:004477440.268
centrosome cycleGO:000709810.260
cellular nitrogen compound metabolic processGO:00346412900.252
Human Mouse Fly
biosynthetic processGO:00090582940.231
Human Mouse Fly
regulation of macromolecule metabolic processGO:00602553170.206
Human Mouse Fly
spindle assembly involved in meiosisGO:009030610.202
regulation of signal transductionGO:00099662250.198
Fly
negative regulation of mitosisGO:004583930.198
macromolecule biosynthetic processGO:00090592270.195
Human Mouse Fly
organic substance biosynthetic processGO:19015762890.190
Human Mouse Fly
regulation of cellular macromolecule biosynthetic processGO:20001122220.184
Human Mouse Fly
hemopoiesisGO:00300971830.183
signal transductionGO:00071654550.181
Fly
response to stressGO:00069502630.176
programmed cell deathGO:00125011190.175
protein metabolic processGO:00195381830.168
regulation of cellular protein metabolic processGO:0032268520.162
proteasomal protein catabolic processGO:001049820.160
centrosome duplicationGO:005129810.158
regulation of nucleobase containing compound metabolic processGO:00192192500.155
Human Mouse Fly
negative regulation of nuclear divisionGO:005178430.153
positive regulation of cell cycleGO:004578730.144
single organism organelle organizationGO:19025891990.142
hematopoietic or lymphoid organ developmentGO:00485341910.137
regulation of primary metabolic processGO:00800903110.133
Human Mouse Fly
cell cycle g1 s phase transitionGO:004484310.132
regulation of metabolic processGO:00192223590.130
Human Mouse Fly
regulation of protein ubiquitinationGO:003139630.128
locomotionGO:00400113130.122
cellular aromatic compound metabolic processGO:00067252950.117
Human Mouse Fly
regulation of nucleocytoplasmic transportGO:004682220.115
regulation of apoptotic processGO:0042981980.115
regulation of protein transportGO:005122330.115
regulation of cell communicationGO:00106462320.105
Fly
cell morphogenesis involved in differentiationGO:00009041950.105
nitrogen compound metabolic processGO:00068073190.103
Human Mouse Fly
proteolysis involved in cellular protein catabolic processGO:005160330.102
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.102
specification of symmetryGO:00097992040.100
negative regulation of mitotic cell cycleGO:0045930110.099
regulation of establishment of protein localizationGO:007020140.098
determination of left right symmetryGO:00073681790.097
transcription dna templatedGO:00063511810.097
Human Mouse
dna metabolic processGO:0006259270.097
Human Mouse Fly
cell cycleGO:0007049930.097
Human Mouse Fly
regulation of cell cycleGO:0051726520.096
Human Mouse Fly
regulation of programmed cell deathGO:00430671010.096
organelle organizationGO:00069962270.096
regulation of cellular metabolic processGO:00313233200.095
Human Mouse Fly
determination of bilateral symmetryGO:00098552040.095
modification dependent macromolecule catabolic processGO:004363230.091
gland developmentGO:00487321430.090
mitotic cell cycle processGO:1903047480.090
nucleobase containing compound biosynthetic processGO:00346542050.088
Human Mouse
regulation of cell deathGO:00109411030.085
negative regulation of developmental processGO:0051093650.085
regulation of protein metabolic processGO:0051246560.084
microtubule organizing center organizationGO:003102310.083
single organism metabolic processGO:00447102170.083
digestive system developmentGO:00551232890.083
developmental growthGO:00485891660.083
regulation of rna biosynthetic processGO:20011412130.081
Human Mouse
regulation of multicellular organismal processGO:00512392770.081
Fly
regulation of intracellular protein transportGO:003315730.081
embryonic organ developmentGO:00485683810.080
g1 s transition of mitotic cell cycleGO:000008210.080
regulation of mitotic cell cycleGO:0007346250.079
Fly
protein modification processGO:00362111000.078
cell divisionGO:0051301200.075
regulation of cell activationGO:005086510.074
positive regulation of signal transductionGO:0009967560.074
regulation of molecular functionGO:0065009700.072
regulation of protein modification by small protein conjugation or removalGO:190332030.072
negative regulation of response to stimulusGO:00485851040.071
Fly
camera type eye developmentGO:00430102220.071
regulation of phosphorus metabolic processGO:0051174430.071
immune system developmentGO:00025201910.071
regulation of multicellular organismal developmentGO:20000262230.071
Fly
establishment of protein localization to organelleGO:007259440.070
wnt signaling pathwayGO:0016055800.070
nucleocytoplasmic transportGO:000691340.070
intra s dna damage checkpointGO:003157310.070
intracellular estrogen receptor signaling pathwayGO:003052030.069
cellular macromolecule biosynthetic processGO:00346452240.068
Human Mouse Fly
cellular protein metabolic processGO:00442671290.067
regulation of meiotic cell cycleGO:005144510.067
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.067
positive regulation of cellular catabolic processGO:003133130.066
regulation of dna replicationGO:000627530.066
Human Mouse Fly
chordate embryonic developmentGO:00430092710.066
negative regulation of cellular metabolic processGO:0031324770.065
Human Mouse Fly
mitotic cell cycleGO:0000278640.064
Fly
pancreas developmentGO:0031016840.063
nuclear transportGO:005116940.063
vasculature developmentGO:00019442780.062
ubiquitin dependent protein catabolic processGO:000651130.061
regulation of protein import into nucleusGO:004230620.061
b cell activationGO:004211320.061
organic cyclic compound metabolic processGO:19013603010.060
Human Mouse Fly
single organism nuclear importGO:190259330.060
response to external stimulusGO:00096052640.059
heterocycle biosynthetic processGO:00181302150.058
Human Mouse
rna biosynthetic processGO:00327741810.057
Human Mouse
regulation of protein localization to nucleusGO:190018020.057
cell projection morphogenesisGO:00488582440.057
embryo development ending in birth or egg hatchingGO:00097922710.056
negative regulation of biological processGO:00485193040.056
Human Mouse Fly
negative regulation of cell deathGO:0060548600.056
negative regulation of cellular processGO:00485232830.055
Human Mouse Fly
regulation of protein modification processGO:0031399290.054
maintenance of locationGO:005123540.054
microtubule polymerizationGO:004678520.053
spindle assembly involved in female meiosisGO:000705610.053
regulation of transcription dna templatedGO:00063552130.053
Human Mouse
response to organic substanceGO:00100331530.052
negative regulation of signalingGO:0023057960.052
Fly
mitotic dna damage checkpointGO:004477340.052
deathGO:00162651210.051
cell growthGO:0016049570.051
regulation of catalytic activityGO:0050790550.051
cellular response to chemical stimulusGO:00708871570.051
regenerationGO:0031099910.051
regulation of cytoplasmic transportGO:190364940.050
regulation of rna metabolic processGO:00512522240.050
Human Mouse
protein localization to nucleusGO:003450430.049
protein importGO:001703830.049
regulation of biosynthetic processGO:00098892500.048
Human Mouse Fly
generation of neuronsGO:00486993850.048
single organism biosynthetic processGO:0044711710.048
agingGO:000756820.047
regulation of phosphate metabolic processGO:0019220430.047
protein import into nucleusGO:000660630.046
positive regulation of catabolic processGO:000989640.045
negative regulation of chromosome organizationGO:200125110.044
regulation of bindingGO:005109830.044
positive regulation of cellular processGO:00485222010.044
positive regulation of biological processGO:00485182530.044
centrosome organizationGO:005129710.042
positive regulation of metabolic processGO:00098931080.042
stem cell developmentGO:0048864820.041
heart developmentGO:00075073130.040
cell cycle g2 m phase transitionGO:004483940.040
response to external biotic stimulusGO:0043207970.040
kupffer s vesicle developmentGO:0070121500.040
response to endogenous stimulusGO:0009719830.040
apoptotic processGO:00069151160.039
rna metabolic processGO:00160702190.039
Human Mouse
regulation of cell differentiationGO:00455951420.039
axonogenesisGO:00074091520.038
response to chemicalGO:00422213200.038
cell deathGO:00082191210.038
cell morphogenesisGO:00009022890.038
nucleobase containing compound metabolic processGO:00061392740.037
Human Mouse Fly
regulation of cellular response to growth factor stimulusGO:0090287350.037
protein targeting to nucleusGO:004474430.037
meiotic spindle organizationGO:000021210.037
regulation of cardiac muscle tissue developmentGO:005502410.036
cell surface receptor signaling pathwayGO:00071663250.036
Fly
immune system processGO:00023762410.036
establishment of localizationGO:00512342440.036
cellular protein modification processGO:00064641000.035
regulation of response to stimulusGO:00485832690.035
Fly
urogenital system developmentGO:0001655970.035
cell proliferationGO:0008283800.035
g2 m transition of mitotic cell cycleGO:000008640.034
nuclear importGO:005117030.034
spindle assemblyGO:005122520.034
cell cycle processGO:0022402530.034
Fly
regulation of cellular protein catabolic processGO:190336210.033
regulation of nucleic acid templated transcriptionGO:19035062130.033
Human Mouse
cilium morphogenesisGO:0060271850.033
regulation of stem cell differentiationGO:200073640.033
aromatic compound biosynthetic processGO:00194382170.033
Human Mouse
cartilage developmentGO:0051216960.032
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.032
Fly
developmental cell growthGO:0048588520.032
negative regulation of protein phosphorylationGO:000193340.032
phosphorus metabolic processGO:00067931090.032
negative regulation of metabolic processGO:0009892860.031
Human Mouse Fly
meiosis iGO:000712710.031
kidney developmentGO:0001822920.031
regulation of protein catabolic processGO:004217610.031
neuron differentiationGO:00301823530.031
phosphate containing compound metabolic processGO:00067961080.031
cytokinesisGO:000091030.031
head developmentGO:00603223030.031
cellular response to dna damage stimulusGO:0006974240.031
mitotic nuclear divisionGO:0007067180.030
embryonic organ morphogenesisGO:00485622740.030
positive regulation of nucleobase containing compound metabolic processGO:0045935690.030
organelle localizationGO:0051640490.030
response to uvGO:000941130.030
positive regulation of cell communicationGO:0010647560.029
connective tissue developmentGO:0061448990.029
regulation of protein bindingGO:004339330.029
peptidyl threonine phosphorylationGO:001810710.029
chromosome organizationGO:0051276310.029
negative regulation of programmed cell deathGO:0043069580.029
negative regulation of organelle organizationGO:001063940.029
tissue regenerationGO:0042246740.029
cellular localizationGO:0051641970.028
negative regulation of apoptotic processGO:0043066550.028
negative regulation of protein transportGO:005122430.027
gliogenesisGO:0042063450.027
response to abiotic stimulusGO:00096281220.027
transcription from rna polymerase ii promoterGO:0006366800.027
histone phosphorylationGO:001657220.027
dna biosynthetic processGO:007189730.027
negative regulation of signal transductionGO:0009968940.027
Fly
small molecule metabolic processGO:0044281770.027
regulation of protein targetingGO:190353320.027
regulation of cell proliferationGO:0042127370.027
oxoacid metabolic processGO:0043436310.026
negative regulation of multicellular organismal processGO:0051241690.026
positive regulation of cell divisionGO:005178120.026
response to biotic stimulusGO:0009607970.026
renal system developmentGO:0072001940.026
heterocycle metabolic processGO:00464832900.026
Human Mouse Fly
negative regulation of cellular catabolic processGO:003133030.026
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.026
response to other organismGO:0051707970.026
intracellular signal transductionGO:0035556850.025
b cell differentiationGO:003018310.025
glial cell differentiationGO:0010001420.025
establishment of organelle localizationGO:0051656450.025
ion transportGO:00068111140.025
positive regulation of signalingGO:0023056560.025
cellular response to radiationGO:007147840.024
negative regulation of catabolic processGO:000989530.024
hepaticobiliary system developmentGO:0061008980.024
dna replication checkpointGO:000007610.024
tube morphogenesisGO:00352393490.024
positive regulation of transportGO:005105020.024
cellular macromolecule metabolic processGO:00442603910.023
Human Mouse Fly
peptidyl serine modificationGO:001820920.023
positive regulation of gtp catabolic processGO:003312610.023
positive regulation of canonical wnt signaling pathwayGO:009026340.023
metencephalon developmentGO:0022037270.023
organonitrogen compound metabolic processGO:1901564740.022
microtubule polymerization or depolymerizationGO:003110930.022
cellular nitrogen compound biosynthetic processGO:00442712180.022
Human Mouse
leukocyte activationGO:0045321120.022
positive regulation of cellular protein metabolic processGO:0032270220.022
negative regulation of macromolecule metabolic processGO:0010605760.022
Human Mouse Fly
brain developmentGO:00074202930.022
regulation of cell cycle processGO:0010564200.022
immunoglobulin mediated immune responseGO:001606430.021
negative regulation of cell cycleGO:0045786140.021
Human Mouse
response to woundingGO:00096111160.021
growthGO:00400071740.021
positive regulation of nitrogen compound metabolic processGO:0051173690.020
positive regulation of muscle organ developmentGO:004863610.020
regulation of cell cycle phase transitionGO:190198780.020
heart morphogenesisGO:00030071560.020
cell cycle arrestGO:000705010.020
regulation of cellular component organizationGO:0051128860.020
reciprocal dna recombinationGO:003582510.020
negative regulation of molecular functionGO:0044092230.019
negative regulation of protein metabolic processGO:0051248160.019
sequestering of metal ionGO:005123830.019
positive regulation of map kinase activityGO:004340630.019
macromolecule modificationGO:00434121110.019
cell part morphogenesisGO:00329902460.019
regulation of protein phosphorylationGO:0001932180.019
regulation of transportGO:0051049450.019
protein modification by small protein conjugation or removalGO:0070647140.019
response to radiationGO:0009314510.019
proteolysisGO:0006508380.019
macromolecular complex subunit organizationGO:0043933740.019
Mouse
regulation of proteolysisGO:0030162240.019
leukocyte proliferationGO:007066110.018
stem cell maintenanceGO:001982740.018
negative regulation of cell communicationGO:0010648960.018
Fly
cell activationGO:0001775160.018
mitotic cell cycle embryonicGO:004544820.018
Fly
negative regulation of gene expressionGO:0010629650.018
Human Mouse
cellular amine metabolic processGO:004410620.018
digestive tract developmentGO:00485652650.018
positive regulation of cellular biosynthetic processGO:0031328680.018
protein phosphorylationGO:0006468470.017
transportGO:00068102200.017
cellular ketone metabolic processGO:0042180110.017
protein modification by small protein conjugationGO:0032446130.017
morphogenesis of an epitheliumGO:00020093330.017
female meiosis iiGO:000714710.017
cellular response to organic substanceGO:00713101050.017
cell cycle checkpointGO:000007570.017
organelle fissionGO:0048285230.017
negative regulation of leukocyte differentiationGO:190210610.017
positive regulation of response to stimulusGO:0048584800.016
response to oxygen levelsGO:0070482250.016
protein polyubiquitinationGO:000020940.016
multi organism processGO:00517041340.016
positive regulation of nucleic acid templated transcriptionGO:1903508570.016
mononuclear cell proliferationGO:003294310.016
nucleic acid metabolic processGO:00903042440.016
Human Mouse Fly
regulation of mitosisGO:000708890.016
regulation of wnt signaling pathwayGO:0030111530.016
nucleic acid templated transcriptionGO:00976591810.016
Human Mouse
regulation of cell divisionGO:0051302120.016
positive regulation of macromolecule metabolic processGO:0010604930.016
oocyte maturationGO:000155640.016
response to decreased oxygen levelsGO:0036293250.015
dna alkylationGO:000630580.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
protein ubiquitinationGO:0016567110.015
regulation of cellular amine metabolic processGO:003323800.015
fibroblast growth factor receptor signaling pathwayGO:0008543220.015
negative regulation of cell cycle processGO:001094890.015
carboxylic acid metabolic processGO:0019752220.015
determination of heart left right asymmetryGO:00613711170.015
response to light stimulusGO:0009416460.015
regulation of cellular amino acid metabolic processGO:000652100.014
positive regulation of biosynthetic processGO:0009891680.014
negative regulation of cell developmentGO:0010721260.014
wound healingGO:0042060900.014
nuclear divisionGO:0000280230.014
macromolecule localizationGO:0033036540.014
embryonic heart tube morphogenesisGO:00031431080.014
response to drugGO:004249330.014
positive regulation of striated muscle tissue developmentGO:004584410.014
regulation of cellular ketone metabolic processGO:001056570.014
amine metabolic processGO:000930820.014
regulation of heart growthGO:006042020.014
multicellular organismal response to stressGO:003355520.014
regulation of reproductive processGO:200024140.014
negative regulation of catalytic activityGO:0043086210.013
negative regulation of intracellular transportGO:003238730.013
positive regulation of chromosome segregationGO:005198410.013
cellular component biogenesisGO:00440851780.013
female meiotic divisionGO:000714320.013
regulation of nucleoside metabolic processGO:000911820.013
embryonic heart tube developmentGO:00350501330.013
response to hexoseGO:000974630.013
positive regulation of muscle tissue developmentGO:190186310.013
multicellular organism growthGO:003526440.013
negative regulation of cellular component organizationGO:0051129160.013
reciprocal meiotic recombinationGO:000713110.013
positive regulation of nucleotide catabolic processGO:003081310.013
organic acid metabolic processGO:0006082310.013
cell cycle phase transitionGO:004477090.013
regulation of wnt signaling pathway involved in dorsal ventral axis specificationGO:200005350.013
eye morphogenesisGO:00485921440.013
posttranscriptional regulation of gene expressionGO:0010608140.013
positive regulation of catalytic activityGO:0043085250.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
cellular response to oxygen levelsGO:007145310.013
gene silencingGO:001645840.012
neuron projection developmentGO:00311751800.012
cellular aldehyde metabolic processGO:000608140.012
positive regulation of nucleoside metabolic processGO:004597910.012
regulation of glial cell differentiationGO:004568540.012
dna integrity checkpointGO:003157060.012
positive regulation of cell activationGO:005086710.012
somatic stem cell maintenanceGO:003501910.012
antimicrobial humoral responseGO:001973020.012
liver developmentGO:0001889960.012
digestive tract morphogenesisGO:00485462310.012
fertilizationGO:000956630.012
regulation of growthGO:0040008420.012
regulation of nucleotide catabolic processGO:003081120.012
anterior posterior pattern specificationGO:00099521520.012
negative regulation of cell differentiationGO:0045596460.012
negative regulation of mitotic cell cycle phase transitionGO:190199150.012
establishment of rna localizationGO:005123630.012
response to growth factorGO:0070848390.012
regulation of lipid catabolic processGO:005099420.012
lymphocyte activationGO:0046649100.012
convergent extension involved in gastrulationGO:0060027710.012
cell migrationGO:00164772370.012
regulation of protein processingGO:0070613100.011
neural tube patterningGO:0021532330.011
intracellular transportGO:0046907320.011
positive regulation of rna biosynthetic processGO:1902680570.011
g2 dna damage checkpointGO:003157230.011
homeostatic processGO:00425921420.011
positive regulation of cellular amine metabolic processGO:003324000.011
epithelial cell morphogenesisGO:000338220.011
protein dephosphorylationGO:000647030.011
organic cyclic compound biosynthetic processGO:19013622230.011
Human Mouse
axis elongationGO:0003401310.011
regulation of gtp catabolic processGO:003312420.011
production of molecular mediator of immune responseGO:000244020.011
regulation of dna metabolic processGO:0051052110.011
Human Mouse Fly
pronuclear migrationGO:003504610.011
protein acylationGO:004354330.011
regulation of signalingGO:00230512350.011
Fly
male meiosisGO:000714020.011
otolith formationGO:003247520.011
sensory organ morphogenesisGO:00905962000.011
regulation of cell shapeGO:000836010.011
response to fibroblast growth factorGO:0071774220.011
developmental maturationGO:0021700340.011
regulation of cell growthGO:0001558290.010
regulation of neuron projection developmentGO:0010975400.010
exocrine pancreas developmentGO:0031017280.010
skeletal system developmentGO:00015011810.010
protein maturationGO:0051604120.010
mitochondrion organizationGO:000700540.010
regulation of mitotic cell cycle phase transitionGO:190199080.010
glucose homeostasisGO:004259310.010
guanosine containing compound metabolic processGO:190106840.010
regionalizationGO:00030022740.010
calcium ion transport into cytosolGO:006040230.010
regulation of cell developmentGO:00602841000.010
cellular amino acid metabolic processGO:000652070.010
positive regulation of protein metabolic processGO:0051247230.010
regulation of stem cell proliferationGO:007209120.010

gmnn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
nervous system diseaseDOID:86300.028