Danio rerio

0 known processes

grn1

granulin 1

(Aliases: MGC136318,zgc:136318)

grn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to other organismGO:0051707970.200
immunoglobulin mediated immune responseGO:001606430.168
tyrosine phosphorylation of stat proteinGO:000726010.157
cellular ketone metabolic processGO:0042180110.146
small molecule metabolic processGO:0044281770.107
response to external biotic stimulusGO:0043207970.103
regulation of production of molecular mediator of immune responseGO:000270010.098
single organism metabolic processGO:00447102170.096
regulation of cyclic nucleotide biosynthetic processGO:0030802150.094
complement activationGO:000695630.093
larval developmentGO:000216420.088
response to external stimulusGO:00096052640.088
nitrogen compound metabolic processGO:00068073190.084
organonitrogen compound metabolic processGO:1901564740.083
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.081
regulation of stem cell proliferationGO:007209120.081
humoral immune response mediated by circulating immunoglobulinGO:000245530.079
regulation of cellular amino acid metabolic processGO:000652100.079
regulation of signalingGO:00230512350.078
organic substance biosynthetic processGO:19015762890.078
stem cell proliferationGO:007208940.078
regulation of cellular amine metabolic processGO:003323800.077
b cell mediated immunityGO:001972430.077
activation of immune responseGO:000225390.077
oxoacid metabolic processGO:0043436310.074
regulation of peptidyl tyrosine phosphorylationGO:005073010.074
regulation of establishment of protein localizationGO:007020140.071
hematopoietic or lymphoid organ developmentGO:00485341910.069
response to biotic stimulusGO:0009607970.066
maintenance of locationGO:005123540.066
amine metabolic processGO:000930820.065
immune system processGO:00023762410.062
organic cyclic compound biosynthetic processGO:19013622230.061
cellular nitrogen compound metabolic processGO:00346412900.060
response to drugGO:004249330.057
protein activation cascadeGO:007237660.056
digestive system developmentGO:00551232890.054
cellular amine metabolic processGO:004410620.053
regulation of developmental processGO:00507932470.053
cellular biosynthetic processGO:00442492860.052
symbiosis encompassing mutualism through parasitismGO:004440340.052
positive regulation of stress activated mapk cascadeGO:003287430.052
cell projection morphogenesisGO:00488582440.051
regulation of cell activationGO:005086510.050
alcohol biosynthetic processGO:004616520.049
regulation of synapse organizationGO:005080730.049
regulation of response to stimulusGO:00485832690.048
multicellular organism growthGO:003526440.048
single organism biosynthetic processGO:0044711710.046
regulation of jak stat cascadeGO:004642530.046
positive regulation of immune effector processGO:000269930.045
organic cyclic compound metabolic processGO:19013603010.045
positive regulation of cell activationGO:005086710.045
biosynthetic processGO:00090582940.043
carboxylic acid metabolic processGO:0019752220.043
regulation of extrinsic apoptotic signaling pathwayGO:200123630.042
complement activation classical pathwayGO:000695830.041
production of molecular mediator of immune responseGO:000244020.041
blood vessel morphogenesisGO:00485142160.041
synaptic growth at neuromuscular junctionGO:005112420.040
regulation of tyrosine phosphorylation of stat proteinGO:004250910.040
lymphocyte mediated immunityGO:000244950.040
regulation of signal transductionGO:00099662250.039
positive regulation of striated muscle cell differentiationGO:005115510.039
cellular amino acid metabolic processGO:000652070.038
regulation of multicellular organismal processGO:00512392770.037
positive regulation of jnk cascadeGO:004633030.037
organic acid metabolic processGO:0006082310.037
locomotionGO:00400113130.037
regulation of cell communicationGO:00106462320.036
angiogenesisGO:00015251580.036
response to stressGO:00069502630.036
positive regulation of secretion by cellGO:190353210.035
response to virusGO:0009615210.034
regulation of inflammatory responseGO:005072720.034
morphogenesis of an epitheliumGO:00020093330.034
agingGO:000756820.034
ribosome assemblyGO:004225510.033
zymogen activationGO:003163830.033
leukocyte differentiationGO:0002521250.033
cellular component movementGO:00069283350.033
regulation of cellular ketone metabolic processGO:001056570.032
regulation of protein import into nucleusGO:004230620.032
gene expressionGO:00104672520.032
long chain fatty acid metabolic processGO:000167610.031
regulation of synaptic growth at neuromuscular junctionGO:000858210.031
i kappab kinase nf kappab signalingGO:000724940.031
positive regulation of cytokine productionGO:000181920.030
regulation of blood pressureGO:000821710.030
regulation of cytokine productionGO:000181730.030
immune responseGO:0006955280.029
positive regulation of dna metabolic processGO:005105410.029
defense response to bacteriumGO:0042742220.029
secondary metabolic processGO:001974830.029
positive regulation of lymphocyte mediated immunityGO:000270810.029
response to bacteriumGO:0009617580.028
nuclear transportGO:005116940.028
interspecies interaction between organismsGO:004441940.028
regulation of multicellular organism growthGO:004001440.028
response to nutrientGO:000758430.028
phosphorus metabolic processGO:00067931090.027
regulation of multicellular organismal developmentGO:20000262230.027
regulation of protein transportGO:005122330.027
regulation of metabolic processGO:00192223590.027
immune system developmentGO:00025201910.027
sensory perception of chemical stimulusGO:000760630.027
cell migrationGO:00164772370.026
regulation of cytoplasmic transportGO:190364940.026
leukocyte proliferationGO:007066110.026
striated muscle tissue developmentGO:00147061100.026
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.026
regulation of biological qualityGO:00650082630.026
membrane fusionGO:006102520.026
cellular amide metabolic processGO:004360340.025
camera type eye developmentGO:00430102220.025
nucleocytoplasmic transportGO:000691340.025
cell motilityGO:00488702440.025
digestive tract developmentGO:00485652650.024
b cell activationGO:004211320.024
cellular nitrogen compound biosynthetic processGO:00442712180.024
hydrogen peroxide metabolic processGO:004274320.023
brain developmentGO:00074202930.023
immune effector processGO:0002252230.023
regulation of tube sizeGO:003515020.023
regulation of metal ion transportGO:001095940.023
positive regulation of transportGO:005105020.023
nuclear importGO:005117030.023
regulation of epithelial cell proliferationGO:005067830.022
positive regulation of biological processGO:00485182530.022
multi organism processGO:00517041340.022
regulation of i kappab kinase nf kappab signalingGO:004312240.022
heterocycle metabolic processGO:00464832900.022
positive regulation of multicellular organismal processGO:0051240520.022
extrinsic apoptotic signaling pathwayGO:009719130.022
viral processGO:001603210.022
immunoglobulin productionGO:000237710.022
cellular response to chemical stimulusGO:00708871570.022
positive regulation of multi organism processGO:004390230.022
regulation of phospholipase activityGO:001051720.021
positive regulation of metabolic processGO:00098931080.021
response to corticosteroidGO:003196010.021
organelle fusionGO:004828430.021
localization of cellGO:00516742440.021
energy homeostasisGO:009700930.021
regulation of response to cytokine stimulusGO:006075930.021
hemopoiesisGO:00300971830.021
gastrulationGO:00073692080.021
signal transductionGO:00071654550.021
endosomal transportGO:001619720.020
apoptotic process involved in developmentGO:190274220.020
collagen metabolic processGO:003296320.020
nucleobase containing compound metabolic processGO:00061392740.020
lipid storageGO:001991510.020
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.020
gland developmentGO:00487321430.020
positive regulation of leukocyte differentiationGO:190210710.020
regulation of cellular metabolic processGO:00313233200.020
regulation of immune system processGO:0002682340.020
type i interferon productionGO:003260620.020
regulation of macromolecule metabolic processGO:00602553170.020
very long chain fatty acid biosynthetic processGO:004276140.019
regulation of nucleoside metabolic processGO:000911820.019
positive regulation of jak stat cascadeGO:004642720.019
steroid biosynthetic processGO:000669450.019
guanosine containing compound metabolic processGO:190106840.019
protein targeting to nucleusGO:004474430.019
response to woundingGO:00096111160.019
programmed cell deathGO:00125011190.019
positive regulation of stem cell proliferationGO:200064810.019
regulation of tyrosine phosphorylation of stat3 proteinGO:004251610.019
immune response activating signal transductionGO:000275750.019
somatic cell dna recombinationGO:001644410.019
adaptive immune responseGO:000225050.019
regulation of protein complex assemblyGO:004325430.018
single organism membrane fusionGO:004480120.018
intracellular signal transductionGO:0035556850.018
aromatic compound biosynthetic processGO:00194382170.018
glucocorticoid metabolic processGO:000821120.018
negative regulation of chemotaxisGO:005092240.018
lymphocyte proliferationGO:004665110.018
regulation of programmed cell deathGO:00430671010.018
b cell differentiationGO:003018310.018
mononuclear cell proliferationGO:003294310.017
positive regulation of cytosolic calcium ion concentrationGO:000720440.017
regulation of cysteine type endopeptidase activityGO:2000116210.017
regulation of reproductive processGO:200024140.017
cellular modified amino acid metabolic processGO:000657530.017
cellular transition metal ion homeostasisGO:004691630.016
negative regulation of nucleocytoplasmic transportGO:004682320.016
cell morphogenesisGO:00009022890.016
blood circulationGO:0008015870.016
regulation of bindingGO:005109830.016
cellular aromatic compound metabolic processGO:00067252950.016
single organism nuclear importGO:190259330.016
nucleobase containing compound biosynthetic processGO:00346542050.016
embryo development ending in birth or egg hatchingGO:00097922710.016
liver developmentGO:0001889960.016
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.016
positive regulation of muscle cell differentiationGO:005114910.016
negative regulation of defense responseGO:003134820.016
protein localization to nucleusGO:003450430.015
digestive tract morphogenesisGO:00485462310.015
spermatid developmentGO:000728620.015
antimicrobial humoral responseGO:001973020.015
regulation of protein localization to nucleusGO:190018020.015
gtp metabolic processGO:004603940.015
negative regulation of cytokine mediated signaling pathwayGO:000196020.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.015
cell agingGO:000756920.015
positive regulation of oligodendrocyte differentiationGO:004871410.015
cell surface receptor signaling pathwayGO:00071663250.015
response to vitaminGO:003327330.015
lymphangiogenesisGO:0001946250.015
lipid metabolic processGO:0006629520.015
regulation of protein metabolic processGO:0051246560.015
developmental programmed cell deathGO:001062340.015
lateral inhibitionGO:004633110.015
response to unfolded proteinGO:000698620.015
centrosome organizationGO:005129710.015
multicellular organismal metabolic processGO:004423620.014
type i interferon biosynthetic processGO:004535110.014
cellular response to prostaglandin stimulusGO:007137930.014
response to oxygen radicalGO:000030520.014
regulation of synapse assemblyGO:005196330.014
regulation of response to extracellular stimulusGO:003210410.014
multi organism cellular processGO:004476420.014
positive regulation of developmental processGO:0051094500.014
gtp catabolic processGO:000618420.014
negative regulation of response to cytokine stimulusGO:006076120.014
positive regulation of cellular amine metabolic processGO:003324000.014
protein import into nucleusGO:000660630.014
positive regulation of myeloid cell differentiationGO:004563920.014
developmental growthGO:00485891660.014
regulation of cellular biosynthetic processGO:00313262450.014
neuroblast proliferationGO:000740520.014
response to ketoneGO:190165410.014
humoral immune responseGO:000695950.014
regulation of cytokine mediated signaling pathwayGO:000195930.014
positive regulation of production of molecular mediator of immune responseGO:000270210.014
fatty acid biosynthetic processGO:000663340.014
regulation of neural precursor cell proliferationGO:200017730.014
response to chemicalGO:00422213200.014
negative regulation of protein import into nucleusGO:004230820.014
cytoskeleton dependent cytokinesisGO:006164030.014
positive regulation of camp biosynthetic processGO:003081920.014
energy reserve metabolic processGO:000611220.014
cell projection organizationGO:00300302840.013
negative regulation of response to stimulusGO:00485851040.013
long chain fatty acid transportGO:001590910.013
embryonic skeletal system morphogenesisGO:0048704930.013
fatty acid elongationGO:003049710.013
cellular protein catabolic processGO:004425740.013
defense response to other organismGO:0098542330.013
regulation of neuronal synaptic plasticityGO:004816810.013
cellular component morphogenesisGO:00329893360.013
cellular response to unfolded proteinGO:003462020.013
leukocyte mediated cytotoxicityGO:000190910.013
photoreceptor cell fate specificationGO:004370410.013
response to organic substanceGO:00100331530.013
organ regenerationGO:003110010.013
response to alkaloidGO:004327920.013
positive regulation of protein polymerizationGO:003227320.013
establishment of protein localization to organelleGO:007259440.013
cerebellar granular layer developmentGO:002168130.013
negative regulation of protein phosphorylationGO:000193340.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
regulation of gene expressionGO:00104682650.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
rna stabilizationGO:004348940.013
regulation of stem cell differentiationGO:200073640.013
regulation of gtpase activityGO:004308720.013
growthGO:00400071740.013
neuron developmentGO:00486662620.013
positive regulation of apoptotic signaling pathwayGO:200123510.012
astrocyte differentiationGO:004870810.012
actin filament polymerizationGO:003004120.012
muscle structure developmentGO:00610611960.012
lymph vessel developmentGO:0001945270.012
regulation of protein catabolic processGO:004217610.012
cognitionGO:005089010.012
response to topologically incorrect proteinGO:003596620.012
modification dependent macromolecule catabolic processGO:004363230.012
regulation of response to biotic stimulusGO:000283120.012
regulation of immunoglobulin productionGO:000263710.012
negative regulation of immune responseGO:005077720.012
regulation of wound healingGO:006104120.012
stem cell differentiationGO:00488631170.012
phagocytosisGO:000690930.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
protein importGO:001703830.012
regulation of transcription dna templatedGO:00063552130.012
peptide transportGO:001583310.012
sensory perception of smellGO:000760820.012
chemosensory behaviorGO:000763510.012
xenobiotic metabolic processGO:000680540.012
peptide metabolic processGO:000651810.012
proteasomal protein catabolic processGO:001049820.012
endoplasmic reticulum unfolded protein responseGO:003096820.012
rna metabolic processGO:00160702190.012
transcription from rna polymerase ii promoterGO:0006366800.012
positive regulation of cell killingGO:003134320.012
atp catabolic processGO:000620040.012
purine ribonucleoside monophosphate catabolic processGO:000916940.012
internal peptidyl lysine acetylationGO:001839320.012
purine nucleoside monophosphate catabolic processGO:000912840.012
modification of morphology or physiology of other organismGO:003582140.012
steroid metabolic processGO:000820270.012
positive regulation of immune responseGO:0050778110.011
cytokinesisGO:000091030.011
cellular response to lipopolysaccharideGO:007122230.011
cellular protein metabolic processGO:00442671290.011
sensory system developmentGO:0048880760.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
cell part morphogenesisGO:00329902460.011
alpha amino acid metabolic processGO:190160530.011
nephron tubule morphogenesisGO:007207810.011
nik nf kappab signalingGO:003806110.011
mrna stabilizationGO:004825540.011
regulation of primary metabolic processGO:00800903110.011
ameboidal type cell migrationGO:00016671430.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
positive regulation of cellular component biogenesisGO:004408930.011
oxidation reduction processGO:0055114410.011
response to coldGO:000940940.011
negative regulation of biological processGO:00485193040.011
cellular response to xenobiotic stimulusGO:0071466350.011
response to abiotic stimulusGO:00096281220.011
regulation of nucleocytoplasmic transportGO:004682220.011
regulation of developmental growthGO:0048638380.011
nucleic acid metabolic processGO:00903042440.011
neuron projection developmentGO:00311751800.011
regulation of autophagyGO:001050630.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.011
cell killingGO:000190620.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
lymph vessel morphogenesisGO:0036303250.011
gastrulation with mouth forming secondGO:0001702440.011
dna biosynthetic processGO:007189730.011
cellular response to external stimulusGO:007149620.011
regulation of organ growthGO:004662030.011
sprouting angiogenesisGO:0002040530.011
negative regulation of cytoplasmic transportGO:190365020.011
tube morphogenesisGO:00352393490.011
protein secretionGO:000930610.011
central nervous system developmentGO:00074173870.011
regulation of heart growthGO:006042020.011
negative regulation of multi organism processGO:004390130.011
neuron differentiationGO:00301823530.011
regulation of phosphate metabolic processGO:0019220430.011
sleepGO:003043110.011
positive regulation of wound healingGO:009030310.011
positive regulation of signal transductionGO:0009967560.010
regulation of purine nucleotide catabolic processGO:003312120.010
negative regulation of cellular processGO:00485232830.010
endothelial cell differentiationGO:0045446200.010
endocrine processGO:005088620.010
inositol lipid mediated signalingGO:004801720.010
positive regulation of immune system processGO:0002684170.010
positive regulation of reproductive processGO:200024320.010
mitochondrion organizationGO:000700540.010
organism emergence from protective structureGO:007168440.010
defense response to fungusGO:005083220.010
regulation of intracellular protein transportGO:003315730.010
regulation of blood vessel sizeGO:005088020.010
er nucleus signaling pathwayGO:000698420.010
axon developmentGO:00615641660.010
regulation of cellular protein metabolic processGO:0032268520.010
macroautophagyGO:001623610.010
positive regulation of protein complex assemblyGO:003133420.010
neuron neuron synaptic transmissionGO:000727010.010
regulation of rna biosynthetic processGO:20011412130.010
rna biosynthetic processGO:00327741810.010
protein acetylationGO:000647320.010
system processGO:00030081850.010
negative regulation of leukocyte chemotaxisGO:000268930.010

grn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.026
disease of metabolismDOID:001466700.021
inherited metabolic disorderDOID:65500.016
lysosomal storage diseaseDOID:321100.014
lipid storage diseaseDOID:945500.014
eye diseaseDOID:561400.012
eye and adnexa diseaseDOID:149200.012
retinal diseaseDOID:567900.012
sensory system diseaseDOID:005015500.012