Danio rerio

55 known processes

hdr

hematopoietic death receptor

(Aliases: zgc:103531,ZH-DR,MGC103531)

hdr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
myeloid cell differentiationGO:0030099860.741
erythrocyte homeostasisGO:0034101550.684
hemopoiesisGO:00300971830.652
erythrocyte maturationGO:004324980.622
hematopoietic or lymphoid organ developmentGO:00485341910.520
immune system developmentGO:00025201910.509
primitive hemopoiesisGO:0060215270.491
erythrocyte differentiationGO:0030218540.478
primitive erythrocyte differentiationGO:006031950.441
embryonic organ developmentGO:00485683810.380
immune system processGO:00023762410.373
Zebrafish
embryonic hemopoiesisGO:0035162530.343
signal transductionGO:00071654550.322
Human
erythrocyte developmentGO:0048821240.218
tube morphogenesisGO:00352393490.195
homeostasis of number of cellsGO:0048872620.185
homeostatic processGO:00425921420.166
myeloid cell developmentGO:0061515320.158
cell surface receptor signaling pathwayGO:00071663250.132
response to biotic stimulusGO:0009607970.126
Zebrafish
response to external stimulusGO:00096052640.124
Human Zebrafish
response to drugGO:004249330.120
regulation of metabolic processGO:00192223590.119
cellular macromolecule biosynthetic processGO:00346452240.119
organic cyclic compound biosynthetic processGO:19013622230.117
central nervous system developmentGO:00074173870.116
larval developmentGO:000216420.116
brain developmentGO:00074202930.116
toll like receptor signaling pathwayGO:000222440.114
cellular response to lipopolysaccharideGO:007122230.113
antimicrobial humoral responseGO:001973020.111
regulation of transcription dna templatedGO:00063552130.110
regulation of nucleobase containing compound metabolic processGO:00192192500.103
regulation of signalingGO:00230512350.102
Human
blood vessel developmentGO:00015682460.102
negative regulation of developmental processGO:0051093650.100
positive regulation of i kappab kinase nf kappab signalingGO:004312330.099
Human
myeloid cell homeostasisGO:0002262560.098
aromatic compound biosynthetic processGO:00194382170.097
regulation of nucleic acid templated transcriptionGO:19035062130.096
hepaticobiliary system developmentGO:0061008980.095
regulation of macromolecule metabolic processGO:00602553170.093
regulation of biological qualityGO:00650082630.091
pancreas developmentGO:0031016840.090
regulation of intracellular protein transportGO:003315730.089
cellular amide metabolic processGO:004360340.088
phagocytosisGO:000690930.087
response to stressGO:00069502630.087
Human Zebrafish
morphogenesis of an epitheliumGO:00020093330.086
cellular macromolecule metabolic processGO:00442603910.085
cell motilityGO:00488702440.082
regulation of protein targetingGO:190353320.080
regulation of nitrogen compound metabolic processGO:00511712510.078
regulation of biosynthetic processGO:00098892500.077
positive regulation of biological processGO:00485182530.076
immune responseGO:0006955280.076
Zebrafish
liver developmentGO:0001889960.074
heterocycle biosynthetic processGO:00181302150.074
cellular component movementGO:00069283350.073
maintenance of locationGO:005123540.072
agingGO:000756820.071
negative regulation of cellular processGO:00485232830.067
adherens junction organizationGO:003433240.065
rna biosynthetic processGO:00327741810.063
protein metabolic processGO:00195381830.063
regulation of multicellular organismal processGO:00512392770.063
negative regulation of biological processGO:00485193040.059
positive regulation of transcription dna templatedGO:0045893570.059
negative regulation of multicellular organismal processGO:0051241690.059
regulation of multicellular organismal developmentGO:20000262230.058
biosynthetic processGO:00090582940.058
organic substance biosynthetic processGO:19015762890.058
regulation of cellular metabolic processGO:00313233200.058
regulation of cell deathGO:00109411030.057
digestive system developmentGO:00551232890.057
regulation of gene expressionGO:00104682650.056
positive regulation of macromolecule biosynthetic processGO:0010557590.055
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.055
gland developmentGO:00487321430.054
response to other organismGO:0051707970.053
Zebrafish
digestive tract morphogenesisGO:00485462310.053
mesoderm formationGO:0001707430.052
transcription dna templatedGO:00063511810.052
regulation of extrinsic apoptotic signaling pathwayGO:200123630.051
regulation of translational initiationGO:000644610.049
cellular response to chemical stimulusGO:00708871570.049
innate immune responseGO:0045087130.049
Zebrafish
positive regulation of rna biosynthetic processGO:1902680570.049
cellular nitrogen compound metabolic processGO:00346412900.048
regulation of protein complex assemblyGO:004325430.047
regulation of nucleocytoplasmic transportGO:004682220.047
heterocycle metabolic processGO:00464832900.047
response to bacteriumGO:0009617580.046
Zebrafish
cell projection organizationGO:00300302840.046
cellular nitrogen compound biosynthetic processGO:00442712180.046
regulation of bindingGO:005109830.045
regulation of response to stimulusGO:00485832690.045
Human
regulation of signal transductionGO:00099662250.045
Human
regulation of rna biosynthetic processGO:20011412130.044
nucleic acid metabolic processGO:00903042440.044
heart developmentGO:00075073130.044
regulation of anatomical structure morphogenesisGO:00226031300.044
nitrogen compound metabolic processGO:00068073190.044
tetrapyrrole biosynthetic processGO:003301480.044
cellular component morphogenesisGO:00329893360.043
digestive tract developmentGO:00485652650.043
regulation of developmental processGO:00507932470.043
protein import into nucleusGO:000660630.043
negative regulation of cell differentiationGO:0045596460.043
regulation of establishment of protein localizationGO:007020140.042
ion homeostasisGO:0050801410.042
cell cycle g1 s phase transitionGO:004484310.042
regulation of cell differentiationGO:00455951420.041
g1 s transition of mitotic cell cycleGO:000008210.041
exocytosisGO:000688710.041
cellular response to biotic stimulusGO:007121630.040
single organism transportGO:00447652060.040
positive regulation of nitrogen compound metabolic processGO:0051173690.040
peptide transportGO:001583310.040
sensory organ developmentGO:00074233930.040
translational initiationGO:000641330.040
regulation of cellular biosynthetic processGO:00313262450.040
response to abiotic stimulusGO:00096281220.040
Human
nucleobase containing compound biosynthetic processGO:00346542050.040
positive regulation of rna metabolic processGO:0051254590.040
extrinsic apoptotic signaling pathwayGO:009719130.039
regulation of rna metabolic processGO:00512522240.038
specification of symmetryGO:00097992040.038
cellular aromatic compound metabolic processGO:00067252950.037
regulation of macromolecule biosynthetic processGO:00105562250.037
negative regulation of protein complex assemblyGO:003133310.037
multicellular organism growthGO:003526440.037
pattern recognition receptor signaling pathwayGO:000222150.037
response to chemicalGO:00422213200.037
head developmentGO:00603223030.037
oxoacid metabolic processGO:0043436310.036
establishment of protein localization to organelleGO:007259440.036
intracellular signal transductionGO:0035556850.036
Human
positive regulation of protein complex assemblyGO:003133420.035
cell fate commitmentGO:0045165990.035
positive regulation of metabolic processGO:00098931080.035
regulation of protein bindingGO:004339330.035
negative regulation of signal transductionGO:0009968940.034
generation of neuronsGO:00486993850.034
localization of cellGO:00516742440.034
single organism localizationGO:19025782250.034
cell morphogenesisGO:00009022890.034
mitotic cell cycleGO:0000278640.034
actin polymerization or depolymerizationGO:000815420.033
defense responseGO:0006952470.033
Zebrafish
regulation of cellular macromolecule biosynthetic processGO:20001122220.033
ion transportGO:00068111140.033
locomotionGO:00400113130.032
nucleobase containing compound metabolic processGO:00061392740.032
single organism metabolic processGO:00447102170.032
regulation of protein transportGO:005122330.032
hatching gland developmentGO:004878530.032
programmed cell deathGO:00125011190.031
response to external biotic stimulusGO:0043207970.031
Zebrafish
activation of innate immune responseGO:000221860.031
cellular biosynthetic processGO:00442492860.031
osteoclast differentiationGO:003031610.031
convergent extensionGO:00600261180.030
regulation of ectodermal cell fate specificationGO:004266520.030
heart loopingGO:0001947940.030
negative regulation of cell communicationGO:0010648960.030
nucleic acid templated transcriptionGO:00976591810.030
organic cyclic compound metabolic processGO:19013603010.029
positive regulation of cellular catabolic processGO:003133130.029
regulation of protein import into nucleusGO:004230620.029
phosphorus metabolic processGO:00067931090.029
positive regulation of transportGO:005105020.029
embryo development ending in birth or egg hatchingGO:00097922710.029
macromolecule biosynthetic processGO:00090592270.029
cellular response to molecule of bacterial originGO:007121930.029
defense response to other organismGO:0098542330.029
Zebrafish
endosomal transportGO:001619720.029
positive regulation of gene expressionGO:0010628710.028
organonitrogen compound metabolic processGO:1901564740.028
iron ion homeostasisGO:005507240.028
transcription from rna polymerase ii promoterGO:0006366800.027
phosphate containing compound metabolic processGO:00067961080.027
cellular protein metabolic processGO:00442671290.027
nerve developmentGO:0021675450.027
protein polymerizationGO:005125840.027
stem cell maintenanceGO:001982740.027
response to organic substanceGO:00100331530.026
small molecule metabolic processGO:0044281770.026
phosphorylationGO:0016310690.026
positive regulation of cellular processGO:00485222010.026
protein secretionGO:000930610.026
positive regulation of catabolic processGO:000989640.026
cell proliferationGO:0008283800.026
cell projection assemblyGO:0030031640.026
response to carbohydrateGO:000974330.026
gene expressionGO:00104672520.026
regulation of cell shapeGO:000836010.026
cell cycleGO:0007049930.026
protein importGO:001703830.025
multi organism processGO:00517041340.025
Zebrafish
positive regulation of translationGO:004572710.025
anterior posterior pattern specificationGO:00099521520.025
regulation of multicellular organism growthGO:004001440.025
response to monosaccharideGO:003428430.025
cellular response to external stimulusGO:007149620.024
Human
compound eye developmentGO:004874920.024
ventricular cardiac muscle tissue developmentGO:000322930.024
protein localization to nucleusGO:003450430.024
cellular protein modification processGO:00064641000.024
heme metabolic processGO:004216890.024
determination of left right symmetryGO:00073681790.024
regulation of cytoplasmic transportGO:190364940.024
regulation of cytokine productionGO:000181730.024
positive regulation of nucleobase containing compound metabolic processGO:0045935690.024
regulation of carbohydrate metabolic processGO:000610940.024
positive regulation of cell cycleGO:004578730.023
zymogen activationGO:003163830.023
regionalizationGO:00030022740.023
cellular response to nutrient levelsGO:003166920.023
positive regulation of multicellular organismal processGO:0051240520.023
enzyme linked receptor protein signaling pathwayGO:00071671060.023
establishment of localizationGO:00512342440.023
neuron projection morphogenesisGO:00488121610.022
regulation of i kappab kinase nf kappab signalingGO:004312240.022
Human
proteasomal protein catabolic processGO:001049820.022
cellular component assemblyGO:00226071700.022
gtp metabolic processGO:004603940.022
cell projection morphogenesisGO:00488582440.022
cellular transition metal ion homeostasisGO:004691630.022
response to glucocorticoidGO:005138410.022
negative regulation of signalingGO:0023057960.022
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.022
cellular response to extracellular stimulusGO:003166820.022
regulation of nucleoside metabolic processGO:000911820.022
formation of primary germ layerGO:0001704620.022
nucleocytoplasmic transportGO:000691340.022
negative regulation of signal transduction in absence of ligandGO:190109910.022
cell migrationGO:00164772370.022
regulation of intracellular signal transductionGO:1902531570.021
Human
vasculature developmentGO:00019442780.021
nuclear transportGO:005116940.021
hydrogen peroxide metabolic processGO:004274320.021
epithelial tube morphogenesisGO:00605621480.021
cell morphogenesis involved in differentiationGO:00009041950.021
negative regulation of response to stimulusGO:00485851040.021
positive regulation of cell adhesionGO:004578510.021
innate immune response activating signal transductionGO:000275850.021
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.021
organelle fusionGO:004828430.021
reactive oxygen species biosynthetic processGO:190340910.021
cranial nerve morphogenesisGO:0021602150.021
regulation of cell communicationGO:00106462320.020
Human
negative regulation of gene expressionGO:0010629650.020
production of molecular mediator of immune responseGO:000244020.020
protein modification processGO:00362111000.020
positive regulation of map kinase activityGO:004340630.020
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.020
response to uvGO:000941130.020
protein targeting to nucleusGO:004474430.020
gastrulationGO:00073692080.020
gtp catabolic processGO:000618420.020
hindbrain developmentGO:0030902910.020
regulation of production of molecular mediator of immune responseGO:000270010.020
regulation of primary metabolic processGO:00800903110.019
heart morphogenesisGO:00030071560.019
axon developmentGO:00615641660.019
determination of bilateral symmetryGO:00098552040.019
blood vessel morphogenesisGO:00485142160.019
i kappab kinase nf kappab signalingGO:000724940.019
Human
positive regulation of innate immune responseGO:004508980.019
positive regulation of cell deathGO:0010942290.019
cell morphogenesis involved in neuron differentiationGO:00486671630.019
developmental growthGO:00485891660.019
regulation of blood pressureGO:000821710.019
activation of jun kinase activityGO:000725720.019
pectoral fin developmentGO:0033339500.019
rna metabolic processGO:00160702190.019
chemical homeostasisGO:0048878490.018
growthGO:00400071740.018
regulation of protein localization to nucleusGO:190018020.018
cellular modified amino acid metabolic processGO:000657530.018
iron ion transportGO:000682640.018
mesoderm developmentGO:0007498880.018
response to hexoseGO:000974630.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
regulation of programmed cell deathGO:00430671010.018
toxin transportGO:190199820.017
deathGO:00162651210.017
regulation of molecular functionGO:0065009700.017
b cell mediated immunityGO:001972430.017
defense response to gram positive bacteriumGO:005083060.017
negative regulation of apoptotic processGO:0043066550.017
embryonic organ morphogenesisGO:00485622740.017
cofactor biosynthetic processGO:0051188100.017
lymphocyte proliferationGO:004665110.017
regulation of cell activationGO:005086510.017
muscle structure developmentGO:00610611960.017
regulation of transcription from rna polymerase ii promoterGO:00063571140.017
b cell activationGO:004211320.017
response to hydrogen peroxideGO:004254230.017
cellular response to organic substanceGO:00713101050.016
lipid storageGO:001991510.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
nuclear importGO:005117030.016
protein complex subunit organizationGO:0071822460.016
organelle organizationGO:00069962270.016
positive regulation of wound healingGO:009030310.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.016
macromolecular complex disassemblyGO:003298410.016
organic substance catabolic processGO:1901575280.016
cell fate specificationGO:0001708680.016
cellular response to reactive oxygen speciesGO:003461420.016
cellular response to stressGO:0033554620.016
Human
positive regulation of cell activationGO:005086710.016
positive regulation of cellular component biogenesisGO:004408930.016
regulation of protein polymerizationGO:003227120.015
regulation of glucose importGO:004632410.015
positive regulation of cell divisionGO:005178120.015
neuron differentiationGO:00301823530.015
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.015
cellular ketone metabolic processGO:0042180110.015
regulation of glucose transportGO:001082710.015
modification dependent protein catabolic processGO:001994130.015
regulation of dna replicationGO:000627530.015
mononuclear cell proliferationGO:003294310.015
cellular localizationGO:0051641970.015
regulation of reproductive processGO:200024140.015
glucose importGO:004632320.015
regulation of organ morphogenesisGO:2000027350.015
mitochondrion organizationGO:000700540.015
guanosine containing compound metabolic processGO:190106840.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.015
positive regulation of cellular protein metabolic processGO:0032270220.015
developmental maturationGO:0021700340.015
cell fate commitment involved in formation of primary germ layerGO:0060795260.015
carboxylic acid metabolic processGO:0019752220.015
cell part morphogenesisGO:00329902460.015
peptide metabolic processGO:000651810.015
regulation of myotube differentiationGO:001083020.015
ventricular cardiac muscle tissue morphogenesisGO:005501020.015
regulation of innate immune responseGO:0045088110.015
cellular response to endogenous stimulusGO:0071495680.014
cytokinesisGO:000091030.014
negative regulation of molecular functionGO:0044092230.014
positive regulation of nucleic acid templated transcriptionGO:1903508570.014
epithelial cell differentiationGO:00308551160.014
neuron projection developmentGO:00311751800.014
proteolysis involved in cellular protein catabolic processGO:005160330.014
muscle cell developmentGO:00550011150.014
negative regulation of macromolecule metabolic processGO:0010605760.014
protein stabilizationGO:005082120.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
exocrine pancreas developmentGO:0031017280.014
regulation of ectoderm developmentGO:200038320.014
cellular carbohydrate metabolic processGO:004426240.014
determination of heart left right asymmetryGO:00613711170.014
hemoglobin biosynthetic processGO:004254180.014
response to inorganic substanceGO:0010035380.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
porphyrin containing compound metabolic processGO:0006778100.014
anion transportGO:0006820380.014
regulation of inflammatory responseGO:005072720.014
response to decreased oxygen levelsGO:0036293250.013
leukocyte proliferationGO:007066110.013
regulation of apoptotic processGO:0042981980.013
regulation of reactive oxygen species metabolic processGO:200037720.013
actin filament polymerizationGO:003004120.013
muscle fiber developmentGO:0048747520.013
cardiac chamber formationGO:000320740.013
internal peptidyl lysine acetylationGO:001839320.013
negative regulation of cell fate specificationGO:0009996110.013
response to lipidGO:0033993600.013
regulation of blood vessel sizeGO:005088020.013
positive regulation of cytokine productionGO:000181920.013
cofactor metabolic processGO:0051186150.013
negative regulation of transcription dna templatedGO:0045892450.013
regulation of protein ubiquitinationGO:003139630.013
ectodermal cell fate specificationGO:000171520.013
neuromuscular synaptic transmissionGO:000727420.013
superoxide metabolic processGO:000680120.013
positive regulation of defense responseGO:003134990.013
regulation of synapse organizationGO:005080730.013
response to oxygen radicalGO:000030520.013
negative regulation of embryonic developmentGO:0045992110.013
hemoglobin metabolic processGO:0020027120.012
neuron developmentGO:00486662620.012
ph reductionGO:004585110.012
protein phosphorylationGO:0006468470.012
establishment of endothelial barrierGO:006102830.012
heart valve formationGO:000318840.012
positive regulation of macromolecule metabolic processGO:0010604930.012
eye developmentGO:00016542770.012
positive regulation of cellular metabolic processGO:0031325940.012
regulation of endopeptidase activityGO:0052548230.012
guanosine containing compound catabolic processGO:190106920.012
regulation of cellular amine metabolic processGO:003323800.012
regulation of sequence specific dna binding transcription factor activityGO:005109090.012
interspecies interaction between organismsGO:004441940.012
monovalent inorganic cation transportGO:0015672420.012
negative regulation of myeloid cell differentiationGO:004563810.012
protein complex disassemblyGO:004324110.012
microtubule based processGO:0007017600.012
biological adhesionGO:0022610400.012
cardiac atrium morphogenesisGO:000320920.012
cellular monovalent inorganic cation homeostasisGO:003000420.012
cytoskeleton organizationGO:0007010960.012
cellular homeostasisGO:0019725260.012
leukocyte mediated cytotoxicityGO:000190910.011
negative regulation of gastrulationGO:2000542110.011
macromolecular complex subunit organizationGO:0043933740.011
neurological system processGO:0050877620.011
b cell differentiationGO:003018310.011
g2 m transition of mitotic cell cycleGO:000008640.011
positive regulation of gtp catabolic processGO:003312610.011
leukocyte differentiationGO:0002521250.011
positive regulation of cell communicationGO:0010647560.011
Human
regulation of phosphorus metabolic processGO:0051174430.011
signal transduction in absence of ligandGO:003803410.011
cartilage developmentGO:0051216960.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
cell adhesionGO:0007155400.011
cell cycle arrestGO:000705010.011
oligopeptide transportGO:000685710.011
transportGO:00068102200.011
regulation of protein metabolic processGO:0051246560.011
defense response to bacteriumGO:0042742220.011
Zebrafish
ubiquitin dependent protein catabolic processGO:000651130.011
humoral immune responseGO:000695950.011
aorta developmentGO:003590440.011
cellular component disassemblyGO:002241110.011
negative regulation of multi organism processGO:004390130.011
negative regulation of programmed cell deathGO:0043069580.011
stem cell proliferationGO:007208940.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
protein localization to plasma membraneGO:007265910.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
negative regulation of cell fate commitmentGO:0010454130.011
cardiac atrium developmentGO:000323040.011
centrosome cycleGO:000709810.011
nitric oxide metabolic processGO:004620920.011
positive regulation of immune effector processGO:000269930.011
autophagyGO:000691440.011
positive regulation of jnk cascadeGO:004633030.011
sodium ion transportGO:0006814240.011
regulation of response to stressGO:0080134360.011
regulation of wnt signaling pathwayGO:0030111530.011
bicarbonate transportGO:001570140.011
positive regulation of jun kinase activityGO:004350720.010
chloride transmembrane transportGO:190247640.010
regulation of purine nucleotide catabolic processGO:003312120.010
negative regulation of apoptotic signaling pathwayGO:2001234100.010
protein acylationGO:004354330.010
internal protein amino acid acetylationGO:000647520.010
regulation of wound healingGO:006104120.010
organonitrogen compound biosynthetic processGO:1901566470.010
single fertilizationGO:000733830.010
regulation of gtpase activityGO:004308720.010
granulocyte differentiationGO:003085180.010
response to nutrientGO:000758430.010
peptidyl lysine acetylationGO:001839420.010
regulation of nucleotide catabolic processGO:003081120.010
cation homeostasisGO:0055080330.010
negative regulation of protein phosphorylationGO:000193340.010
microtubule cytoskeleton organizationGO:0000226330.010
macromolecule modificationGO:00434121110.010
somatic muscle developmentGO:000752540.010
negative regulation of dna metabolic processGO:005105340.010
regulation of erythrocyte differentiationGO:004564620.010
fin developmentGO:0033333770.010
mesodermal cell differentiationGO:0048333210.010

hdr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.048
immune system diseaseDOID:291400.048
hematopoietic system diseaseDOID:7400.048
inherited metabolic disorderDOID:65500.024
disease of metabolismDOID:001466700.024
disease of cellular proliferationDOID:1456600.016
Human
cancerDOID:16200.016
Human
organ system cancerDOID:005068600.016
Human