Danio rerio

70 known processes

hif1ab

hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b

(Aliases: wu:fb63a10,MGC55405,zgc:55405,fb63a10,hif1a)

hif1ab biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cognitionGO:005089010.846
Mouse
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.693
Human Mouse Rat
multi organism processGO:00517041340.662
Rat Fly
positive regulation of cellular processGO:00485222010.658
Human Mouse Rat Fly
organic acid metabolic processGO:0006082310.590
Mouse
neuron differentiationGO:00301823530.572
Zebrafish Mouse
regulation of cell deathGO:00109411030.557
Human Zebrafish Mouse Rat Worm
regulation of macromolecule metabolic processGO:00602553170.544
regulation of cell communicationGO:00106462320.523
Human Mouse
generation of neuronsGO:00486993850.518
Zebrafish Mouse
response to hormoneGO:0009725480.505
Rat Fly
single organism metabolic processGO:00447102170.494
Mouse
neuron developmentGO:00486662620.433
Zebrafish
regulation of cellular component organizationGO:0051128860.424
Fly
multicellular organismal reproductive processGO:0048609350.424
Rat Fly
cellular response to hormone stimulusGO:0032870390.418
Rat Fly
regulation of immune system processGO:0002682340.418
Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.417
response to abiotic stimulusGO:00096281220.415
pyruvate metabolic processGO:000609010.413
Mouse
regulation of cellular metabolic processGO:00313233200.405
positive regulation of cellular catabolic processGO:003133130.399
Fly
regulation of gene expressionGO:00104682650.392
organelle organizationGO:00069962270.389
positive regulation of nucleobase containing compound metabolic processGO:0045935690.362
Human Mouse Rat Fly
regulation of anatomical structure sizeGO:0090066330.360
Rat
regulation of multicellular organismal processGO:00512392770.358
Human Mouse Rat
response to biotic stimulusGO:0009607970.355
Rat
negative regulation of cellular processGO:00485232830.349
Human Mouse Rat Worm Fly
signal transductionGO:00071654550.348
Human Mouse
response to chemicalGO:00422213200.344
negative regulation of programmed cell deathGO:0043069580.339
Human Mouse Rat Worm
regulation of metabolic processGO:00192223590.338
response to stressGO:00069502630.337
cell motilityGO:00488702440.332
Mouse Fly
response to oxygen containing compoundGO:1901700550.329
regulation of signal transductionGO:00099662250.324
Human Mouse
regulation of neural precursor cell proliferationGO:200017730.318
Mouse
macromolecule modificationGO:00434121110.316
negative regulation of biological processGO:00485193040.312
Human Mouse Rat Worm Fly
establishment of protein localization to organelleGO:007259440.310
cellular response to nutrient levelsGO:003166920.308
Worm
heterocycle biosynthetic processGO:00181302150.306
morphogenesis of an epitheliumGO:00020093330.306
Mouse
positive regulation of nitrogen compound metabolic processGO:0051173690.303
Human Mouse Rat Fly
organonitrogen compound metabolic processGO:1901564740.298
cellular response to extracellular stimulusGO:003166820.285
Worm
microtubule based processGO:0007017600.283
Human
developmental growthGO:00485891660.274
positive regulation of cellular metabolic processGO:0031325940.272
Human Mouse Rat Fly
regulation of biological qualityGO:00650082630.272
Human Mouse Rat
oxoacid metabolic processGO:0043436310.270
Mouse
phosphorus metabolic processGO:00067931090.260
locomotionGO:00400113130.247
Zebrafish Mouse Fly
embryo development ending in birth or egg hatchingGO:00097922710.243
Mouse
regulation of signalingGO:00230512350.239
Human Mouse
transportGO:00068102200.239
Human Mouse
protein importGO:001703830.234
neuron projection developmentGO:00311751800.232
Zebrafish
positive regulation of macromolecule metabolic processGO:0010604930.226
Human Mouse Rat Fly
regulation of cell differentiationGO:00455951420.224
Mouse
protein targeting to nucleusGO:004474430.222
positive regulation of signal transductionGO:0009967560.221
Mouse
reproductive processGO:0022414400.220
Mouse Rat Fly
regulation of intracellular signal transductionGO:1902531570.218
Human Mouse
response to external stimulusGO:00096052640.213
Zebrafish Rat Worm
single organism organelle organizationGO:19025891990.212
anatomical structure homeostasisGO:0060249360.205
Mouse
response to organic substanceGO:00100331530.200
response to virusGO:0009615210.198
cellular macromolecule metabolic processGO:00442603910.198
intracellular signal transductionGO:0035556850.196
Human Mouse
cellular response to organic substanceGO:00713101050.196
Human Mouse Rat Fly
positive regulation of metabolic processGO:00098931080.195
Human Mouse Rat Fly
negative regulation of growthGO:0045926100.195
Mouse Fly
positive regulation of biological processGO:00485182530.191
Human Mouse Rat Fly
regulation of primary metabolic processGO:00800903110.189
protein secretionGO:000930610.187
positive regulation of cellular component biogenesisGO:004408930.186
regulation of molecular functionGO:0065009700.186
Mouse
axonogenesisGO:00074091520.174
Zebrafish
ras protein signal transductionGO:000726570.173
positive regulation of catabolic processGO:000989640.172
Fly
negative regulation of cell communicationGO:0010648960.172
Human Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.172
enzyme linked receptor protein signaling pathwayGO:00071671060.168
Mouse
growthGO:00400071740.167
Mouse Fly
cell surface receptor signaling pathwayGO:00071663250.167
Mouse
single organism localizationGO:19025782250.161
Human Mouse
aromatic compound biosynthetic processGO:00194382170.159
carboxylic acid metabolic processGO:0019752220.158
Mouse
small molecule metabolic processGO:0044281770.157
Mouse
nucleic acid metabolic processGO:00903042440.156
response to organic cyclic compoundGO:0014070510.149
Rat
cellular protein metabolic processGO:00442671290.149
regulation of rna biosynthetic processGO:20011412130.148
regulation of epithelial cell proliferationGO:005067830.145
regulation of multicellular organismal developmentGO:20000262230.145
Mouse
neuron apoptotic processGO:0051402200.143
stem cell proliferationGO:007208940.141
Mouse
cellular ketone metabolic processGO:0042180110.140
cellular nitrogen compound metabolic processGO:00346412900.140
erk1 and erk2 cascadeGO:007037140.136
negative regulation of response to stimulusGO:00485851040.135
Human Mouse
epithelial tube morphogenesisGO:00605621480.134
Mouse
regulation of stem cell proliferationGO:007209120.133
Mouse
nitrogen compound metabolic processGO:00068073190.133
rna metabolic processGO:00160702190.132
cell part morphogenesisGO:00329902460.132
Zebrafish
positive regulation of rna biosynthetic processGO:1902680570.130
Human Mouse Rat Fly
regulation of protein localization to nucleusGO:190018020.130
organic substance transportGO:0071702580.129
Mouse
positive regulation of gene expressionGO:0010628710.127
Human Mouse Rat Fly
nucleobase containing compound metabolic processGO:00061392740.126
extrinsic apoptotic signaling pathwayGO:009719130.125
regulation of cytoplasmic transportGO:190364940.122
response to nitrogen compoundGO:1901698190.122
Rat Fly
regulation of response to stimulusGO:00485832690.121
Human Mouse Rat
hepaticobiliary system developmentGO:0061008980.120
cellular macromolecule biosynthetic processGO:00346452240.119
carbohydrate metabolic processGO:0005975120.118
Mouse
regulation of developmental processGO:00507932470.117
Mouse
neurological system processGO:0050877620.117
Mouse
regulation of neuron apoptotic processGO:0043523170.116
Human Zebrafish Mouse
regulation of erk1 and erk2 cascadeGO:007037240.114
glial cell proliferationGO:001400940.113
cell projection morphogenesisGO:00488582440.112
Zebrafish
cellular response to peptide hormone stimulusGO:007137550.111
Rat Fly
single organism nuclear importGO:190259330.109
regulation of nucleic acid templated transcriptionGO:19035062130.109
cell growthGO:0016049570.108
Fly
tissue homeostasisGO:0001894250.108
regulation of extrinsic apoptotic signaling pathwayGO:200123630.107
positive regulation of cell deathGO:0010942290.106
Rat
regulation of phosphate metabolic processGO:0019220430.105
cell proliferationGO:0008283800.104
Mouse Rat
regulation of phosphorus metabolic processGO:0051174430.103
mapk cascadeGO:0000165180.103
carbohydrate derivative metabolic processGO:1901135610.101
Mouse
response to endogenous stimulusGO:0009719830.098
Rat Fly
negative regulation of cell growthGO:003030870.098
Fly
adherens junction organizationGO:003433240.095
regulation of cell projection organizationGO:0031344440.095
response to oxidative stressGO:0006979110.093
Human Mouse Rat
agingGO:000756820.091
Worm
hypothalamus cell differentiationGO:002197940.091
Zebrafish
locomotor rhythmGO:004547530.091
negative regulation of nucleobase containing compound metabolic processGO:0045934590.090
Rat
retina development in camera type eyeGO:00600411460.089
Mouse
protein kinase b signalingGO:004349190.088
canonical wnt signaling pathwayGO:0060070480.086
axon developmentGO:00615641660.086
Zebrafish
signal transduction by phosphorylationGO:0023014180.085
regulation of mapk cascadeGO:0043408140.085
nucleic acid templated transcriptionGO:00976591810.084
regulation of phosphorylationGO:0042325260.083
cellular protein modification processGO:00064641000.083
mitotic cell cycleGO:0000278640.082
protein import into nucleusGO:000660630.082
establishment of localizationGO:00512342440.082
Human Mouse
gland developmentGO:00487321430.082
Mouse
neuron deathGO:0070997210.081
embryonic organ morphogenesisGO:00485622740.080
Mouse
negative regulation of neural precursor cell proliferationGO:200017810.079
positive regulation of cell matrix adhesionGO:000195410.079
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.078
Human Mouse Rat Fly
regulation of cell growthGO:0001558290.078
Fly
cellular component biogenesisGO:00440851780.078
response to external biotic stimulusGO:0043207970.077
Rat
regulation of cellular amino acid metabolic processGO:000652100.077
regulation of dna templated transcription in response to stressGO:004362000.076
Human Mouse Rat
negative regulation of signal transductionGO:0009968940.076
Human Mouse
regulation of neuron projection developmentGO:0010975400.076
cellular amino acid metabolic processGO:000652070.075
regulation of purine nucleotide catabolic processGO:003312120.075
behaviorGO:0007610740.075
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.074
Mouse
tube morphogenesisGO:00352393490.074
Mouse
cellular response to endogenous stimulusGO:0071495680.073
Rat Fly
biosynthetic processGO:00090582940.073
regulation of apoptotic processGO:0042981980.071
Human Zebrafish Mouse Rat Worm
urogenital system developmentGO:0001655970.071
cell morphogenesisGO:00009022890.070
Zebrafish Mouse
nuclear importGO:005117030.070
gene expressionGO:00104672520.070
regulation of protein targetingGO:190353320.070
positive regulation of protein kinase b signalingGO:005189710.070
taxisGO:00423301090.069
Zebrafish
cellular amine metabolic processGO:004410620.069
multicellular organism reproductionGO:0032504350.069
Rat Fly
response to temperature stimulusGO:0009266150.068
Worm
guanosine containing compound catabolic processGO:190106920.068
response to corticosteroidGO:003196010.068
Rat
positive regulation of cellular amino acid metabolic processGO:004576400.068
cell morphogenesis involved in differentiationGO:00009041950.068
Zebrafish Mouse
regulation of oligodendrocyte differentiationGO:004871310.067
kidney developmentGO:0001822920.067
cellular component assemblyGO:00226071700.066
regulation of intracellular protein transportGO:003315730.066
cell substrate adhesionGO:003158940.064
negative regulation of multicellular organismal processGO:0051241690.064
Mouse Rat
response to oxygen levelsGO:0070482250.064
regulation of cell sizeGO:0008361290.063
Rat
regulation of cellular biosynthetic processGO:00313262450.063
protein metabolic processGO:00195381830.062
Mouse
notch signaling pathwayGO:0007219350.062
cellular response to external stimulusGO:007149620.061
Rat Worm
regulation of hydrolase activityGO:0051336280.061
blood vessel morphogenesisGO:00485142160.060
Mouse
regulation of protein complex assemblyGO:004325430.060
cellular response to chemical stimulusGO:00708871570.060
Human Mouse Rat Fly
positive regulation of cell communicationGO:0010647560.060
Mouse
reproductionGO:0000003400.060
Rat Fly
negative regulation of signalingGO:0023057960.059
Human Mouse
negative regulation of cell differentiationGO:0045596460.059
neuron projection morphogenesisGO:00488121610.059
Zebrafish
transition metal ion homeostasisGO:005507650.057
Mouse
establishment or maintenance of cell polarityGO:0007163290.057
macrophage chemotaxisGO:004824630.057
regulation of multicellular organism growthGO:004001440.057
cardiac cell fate commitmentGO:006091110.057
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.057
multi organism reproductive processGO:0044703360.057
Rat Fly
macromolecule biosynthetic processGO:00090592270.056
cell cycle processGO:0022402530.056
cell cycleGO:0007049930.056
Fly
negative regulation of secretionGO:005104820.056
protein modification processGO:00362111000.056
phosphate containing compound metabolic processGO:00067961080.055
wnt signaling pathwayGO:0016055800.055
heterocycle metabolic processGO:00464832900.055
regulation of protein kinase b signalingGO:005189680.054
positive regulation of protein complex assemblyGO:003133420.054
single organism transportGO:00447652060.054
Human Mouse
larval developmentGO:000216420.054
amine metabolic processGO:000930820.054
regulation of cell developmentGO:00602841000.053
Mouse
positive regulation of rna metabolic processGO:0051254590.052
Human Mouse Rat Fly
apoptotic processGO:00069151160.052
organic substance biosynthetic processGO:19015762890.052
convergent extensionGO:00600261180.052
mesenchyme developmentGO:00604851270.051
Mouse
renal system developmentGO:0072001940.051
vesicle mediated transportGO:0016192220.051
maintenance of locationGO:005123540.051
regulation of rac protein signal transductionGO:003502010.050
protein localizationGO:0008104400.050
spindle assembly involved in meiosisGO:009030610.050
cellular aromatic compound metabolic processGO:00067252950.050
cellular response to organonitrogen compoundGO:007141750.050
Rat Fly
regulation of neuron differentiationGO:0045664560.049
axon guidanceGO:0007411860.049
Zebrafish
cell migrationGO:00164772370.049
Mouse Fly
regulation of nucleocytoplasmic transportGO:004682220.049
protein localization to nucleusGO:003450430.049
positive regulation of signalingGO:0023056560.048
Mouse
regulation of cellular protein metabolic processGO:0032268520.048
response to steroid hormoneGO:0048545350.048
Rat
cellular response to nitrogen compoundGO:190169960.048
Rat Fly
liver developmentGO:0001889960.047
peptidyl serine modificationGO:001820920.047
regulation of cellular amine metabolic processGO:003323800.047
symbiosis encompassing mutualism through parasitismGO:004440340.047
regulation of protein transportGO:005122330.046
metal ion homeostasisGO:0055065260.046
Mouse
system processGO:00030081850.046
Mouse Rat
negative regulation of protein kinase activityGO:000646940.046
microtubule organizing center organizationGO:003102310.046
positive regulation of epithelial cell proliferationGO:005067910.045
regulation of purine nucleotide metabolic processGO:1900542170.045
response to inorganic substanceGO:0010035380.045
Rat
odontogenesis of dentin containing toothGO:004247510.045
chemical homeostasisGO:0048878490.045
Human Mouse Rat
negative regulation of macromolecule metabolic processGO:0010605760.044
Rat
segmentationGO:0035282970.044
regulation of cellular ketone metabolic processGO:001056570.044
negative regulation of cell deathGO:0060548600.044
Human Mouse Rat Worm
regulation of gtpase activityGO:004308720.044
oxidation reduction processGO:0055114410.043
neurotransmitter secretionGO:000726920.042
membrane organizationGO:0061024210.042
iron ion homeostasisGO:005507240.042
Mouse
regulation of catalytic activityGO:0050790550.042
Mouse
regulation of nucleoside metabolic processGO:000911820.042
actin filament based processGO:0030029640.041
modification dependent protein catabolic processGO:001994130.041
amino acid transportGO:000686520.041
positive regulation of nucleic acid templated transcriptionGO:1903508570.041
Human Mouse Rat Fly
regulation of protein import into nucleusGO:004230620.041
homeostatic processGO:00425921420.041
Human Mouse Rat
cellular biosynthetic processGO:00442492860.041
osteoclast differentiationGO:003031610.041
small gtpase mediated signal transductionGO:000726480.041
mesenchymal cell developmentGO:0014031780.040
Mouse
sexual reproductionGO:0019953360.040
Fly
negative regulation of apoptotic signaling pathwayGO:2001234100.040
Human
cytoskeleton organizationGO:0007010960.040
oocyte developmentGO:0048599140.039
detection of temperature stimulusGO:001604800.039
nucleocytoplasmic transportGO:000691340.039
brain developmentGO:00074202930.039
Zebrafish Mouse
regulation of cellular component sizeGO:0032535300.038
Rat
morphogenesis of a branching structureGO:0001763210.038
phagocytosisGO:000690930.038
peptidyl serine phosphorylationGO:001810510.038
regulation of photoreceptor cell differentiationGO:004653220.037
response to extracellular stimulusGO:0009991100.037
Worm
vasculogenesisGO:0001570410.037
cellular localizationGO:0051641970.037
Human Mouse
positive regulation of molecular functionGO:0044093330.037
autophagyGO:000691440.036
Fly
tissue remodelingGO:004877140.036
Mouse
regulation of synaptic plasticityGO:004816710.036
regulation of autophagyGO:001050630.036
Fly
regulation of rna metabolic processGO:00512522240.036
muscle structure developmentGO:00610611960.035
regulation of gtp catabolic processGO:003312420.035
regulation of dendrite developmentGO:005077330.035
single organism reproductive processGO:0044702400.034
Mouse Rat Fly
positive regulation of stress activated mapk cascadeGO:003287430.034
regulation of peptidyl tyrosine phosphorylationGO:005073010.034
cell morphogenesis involved in neuron differentiationGO:00486671630.034
Zebrafish
regulation of nucleotide catabolic processGO:003081120.034
ubiquitin dependent protein catabolic processGO:000651130.034
neuron neuron synaptic transmissionGO:000727010.034
cellular catabolic processGO:0044248270.034
Mouse Fly
establishment of synaptic vesicle localizationGO:009748010.034
hormone metabolic processGO:0042445190.033
Human
interspecies interaction between organismsGO:004441940.033
monocarboxylic acid metabolic processGO:0032787170.033
Mouse
skeletal muscle organ developmentGO:0060538780.033
establishment of localization in cellGO:0051649770.033
Human Mouse
phosphorylationGO:0016310690.033
negative regulation of cellular metabolic processGO:0031324770.033
Rat
response to nutrientGO:000758430.033
vasculature developmentGO:00019442780.032
Mouse
embryonic organ developmentGO:00485683810.032
Mouse
nephron tubule morphogenesisGO:007207810.032
regulation of growthGO:0040008420.032
Mouse Fly
regulation of nervous system developmentGO:0051960900.032
Mouse
multicellular organismal homeostasisGO:0048871290.032
regulation of neurogenesisGO:0050767870.032
Mouse
cell cell signalingGO:0007267520.031
Mouse
response to decreased oxygen levelsGO:0036293250.031
chordate embryonic developmentGO:00430092710.031
Mouse
blood vessel developmentGO:00015682460.031
Mouse
positive regulation of multicellular organismal processGO:0051240520.031
Human Mouse
positive regulation of erk1 and erk2 cascadeGO:007037420.031
negative regulation of kinase activityGO:003367340.030
lipid storageGO:001991510.030
muscle tissue developmentGO:00605371100.030
pigmentationGO:0043473850.030
compound eye developmentGO:004874920.030
eye developmentGO:00016542770.030
Mouse
positive regulation of notch signaling pathwayGO:004574730.030
rna biosynthetic processGO:00327741810.030
regulation of cellular component biogenesisGO:0044087120.029
protein acetylationGO:000647320.029
positive regulation of phosphate metabolic processGO:0045937210.029
cellular response to oxygen levelsGO:007145310.029
Human Mouse Rat Fly
regulation of cell motilityGO:2000145460.029
Mouse Fly
cell type specific apoptotic processGO:0097285220.029
regulation of nitrogen compound metabolic processGO:00511712510.028
myotube differentiationGO:0014902450.028
cellular response to stressGO:0033554620.028
Human Mouse Rat Worm Fly
regulation of reproductive processGO:200024140.028
response to acid chemicalGO:0001101170.028
Rat
cell matrix adhesionGO:000716040.028
regulation of rho protein signal transductionGO:003502320.028
protein phosphorylationGO:0006468470.028
mitochondrion organizationGO:000700540.028
modulation by virus of host morphology or physiologyGO:001904810.028
dicarboxylic acid transportGO:000683510.028
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.027
regulation of protein catabolic processGO:004217610.027
macromolecular complex assemblyGO:0065003350.027
positive regulation of nucleoside metabolic processGO:004597910.027
dna catabolic processGO:000630810.027
neuron migrationGO:0001764220.027
lateral line system developmentGO:0048925760.027
protein complex localizationGO:003150310.027
exocrine system developmentGO:0035272280.027
muscle cell differentiationGO:00426921390.027
multicellular organism growthGO:003526440.027
localization of cellGO:00516742440.027
Mouse Fly
regulation of protein metabolic processGO:0051246560.027
organic cyclic compound biosynthetic processGO:19013622230.027
neural crest cell developmentGO:0014032620.027
Mouse
organic cyclic compound metabolic processGO:19013603010.026
mitotic cell cycle processGO:1903047480.026
apoptotic signaling pathwayGO:0097190230.026
Human
negative regulation of apoptotic processGO:0043066550.026
Human Mouse Rat Worm
response to light stimulusGO:0009416460.026
Mouse Rat
developmental process involved in reproductionGO:0003006270.026
Mouse Fly
cellular response to organic cyclic compoundGO:0071407380.026
Rat
head developmentGO:00603223030.026
Zebrafish Mouse
peripheral nervous system developmentGO:0007422550.025
regulation of cell migrationGO:0030334400.025
Mouse Fly
lymph vessel developmentGO:0001945270.025
regulation of glial cell proliferationGO:006025140.025
muscle organ developmentGO:00075171010.025
regulation of tube sizeGO:003515020.025
Rat
synaptic target recognitionGO:000803910.025
regulation of hormone levelsGO:0010817210.025
Human Mouse
protein complex biogenesisGO:0070271300.024
epithelial cell differentiationGO:00308551160.024
Mouse
positive regulation of programmed cell deathGO:0043068290.024
Rat
posterior lateral line neuromast developmentGO:0048919200.024
lipid metabolic processGO:0006629520.023
regulation of cell proliferationGO:0042127370.023
Mouse Rat
hematopoietic or lymphoid organ developmentGO:00485341910.023
Mouse
negative regulation of response to cytokine stimulusGO:006076120.023
membrane invaginationGO:001032410.023
skeletal muscle tissue developmentGO:0007519670.023
regulation of protein phosphorylationGO:0001932180.023
cell agingGO:000756920.023
positive regulation of cellular amine metabolic processGO:003324000.022
macromolecule localizationGO:0033036540.022
striated muscle tissue developmentGO:00147061100.022
phagocytosis engulfmentGO:000691110.022
regulation of protein modification processGO:0031399290.022
energy reserve metabolic processGO:000611220.022
somitogenesisGO:0001756870.022
negative regulation of protein transportGO:005122430.022
regulation of cell substrate adhesionGO:001081010.022
single organism biosynthetic processGO:0044711710.022
immune system developmentGO:00025201910.022
Mouse
microtubule cytoskeleton organization involved in mitosisGO:190285010.022
positive regulation of cell substrate adhesionGO:001081110.021
regulation of ras gtpase activityGO:003231820.021
synaptic vesicle transportGO:004848910.021
organic substance catabolic processGO:1901575280.021
Mouse
negative regulation of protein phosphorylationGO:000193340.021
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.021
positive regulation of biosynthetic processGO:0009891680.021
Human Mouse Rat Fly
regionalizationGO:00030022740.021
regulation of localizationGO:00328791040.021
Mouse Fly
deathGO:00162651210.020
developmental cell growthGO:0048588520.020
transcription dna templatedGO:00063511810.020
response to growth factorGO:0070848390.020
Mouse
negative regulation of secretion by cellGO:190353120.020
cell recognitionGO:0008037190.020
skeletal system morphogenesisGO:00487051020.020
neuron recognitionGO:0008038180.020
neural crest cell migrationGO:0001755420.020
Mouse
negative regulation of neurogenesisGO:0050768200.020
single organism behaviorGO:0044708240.020
Mouse
central nervous system developmentGO:00074173870.020
Zebrafish Mouse
negative regulation of gene expressionGO:0010629650.020
Rat
tor signalingGO:003192970.019
Mouse
developmental growth involved in morphogenesisGO:0060560860.019
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.019
regulation of cellular macromolecule biosynthetic processGO:20001122220.019
ovarian follicle developmentGO:000154120.019
cell projection organizationGO:00300302840.019
Zebrafish
response to other organismGO:0051707970.019
Rat
regulation of establishment of protein localizationGO:007020140.019
negative regulation of nitrogen compound metabolic processGO:0051172590.019
Rat
negative regulation of protein import into nucleusGO:004230820.018
cytokinesisGO:000091030.018
cellular hormone metabolic processGO:0034754190.018
response to drugGO:004249330.018
Rat
response to bacteriumGO:0009617580.018
Rat
regulation of protein bindingGO:004339330.018
synaptic vesicle localizationGO:009747910.018
positive regulation of developmental processGO:0051094500.018
Mouse
single organism carbohydrate metabolic processGO:0044723120.018
Mouse
signal transduction in absence of ligandGO:003803410.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
lateral line developmentGO:0048882660.017
response to lipidGO:0033993600.017
Rat
peptidyl amino acid modificationGO:0018193160.017
macromolecular complex subunit organizationGO:0043933740.017
positive regulation of histone modificationGO:003105810.017
positive regulation of cellular protein metabolic processGO:0032270220.017
regulation of organelle organizationGO:0033043290.017
cellular response to dna damage stimulusGO:0006974240.017
Fly
organelle localizationGO:0051640490.017
negative regulation of developmental processGO:0051093650.017
Mouse
stem cell fate commitmentGO:004886510.017
regulation of establishment or maintenance of cell polarityGO:003287820.017
negative regulation of protein complex assemblyGO:003133310.017
positive regulation of nervous system developmentGO:0051962250.017
Mouse
cell fate commitmentGO:0045165990.017
positive regulation of glial cell proliferationGO:006025210.017
positive regulation of purine nucleotide catabolic processGO:003312310.017

hif1ab disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.085
disease of cellular proliferationDOID:1456600.085
organ system cancerDOID:005068600.085
neurodegenerative diseaseDOID:128900.072
nervous system diseaseDOID:86300.072
disease of anatomical entityDOID:700.072
central nervous system diseaseDOID:33100.072
tauopathyDOID:68000.072
cardiovascular system diseaseDOID:128700.019
disease of mental healthDOID:15000.018
dementiaDOID:130700.018
cognitive disorderDOID:156100.018