Danio rerio

29 known processes

hmx2

H6 family homeobox 2

hmx2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ear developmentGO:00435831270.964
sensory organ developmentGO:00074233930.702
inner ear developmentGO:00488391260.643
posterior lateral line system developmentGO:0048915460.569
sensory organ morphogenesisGO:00905962000.536
nephron tubule morphogenesisGO:007207810.524
sensory system developmentGO:0048880760.482
transmembrane transportGO:00550851200.436
neuromast developmentGO:0048884460.421
cellular pigmentationGO:0033059300.420
cellular component movementGO:00069283350.408
regulation of metal ion transportGO:001095940.404
lateral line developmentGO:0048882660.396
inner ear morphogenesisGO:0042472630.374
vasculature developmentGO:00019442780.366
localization of cellGO:00516742440.322
regulation of cell communicationGO:00106462320.321
regulation of cell shapeGO:000836010.320
stem cell proliferationGO:007208940.310
metal ion transportGO:0030001580.303
generation of neuronsGO:00486993850.300
regulation of extrinsic apoptotic signaling pathwayGO:200123630.290
cellular ketone metabolic processGO:0042180110.247
extrinsic apoptotic signaling pathwayGO:009719130.246
nephron morphogenesisGO:007202820.238
single organism localizationGO:19025782250.218
regulation of skeletal muscle tissue developmentGO:004864140.214
regulation of cellular amino acid metabolic processGO:000652100.210
establishment of localizationGO:00512342440.201
neuromast primordium migrationGO:0048883120.198
agingGO:000756820.193
digestive system developmentGO:00551232890.184
lateral line system developmentGO:0048925760.177
pigmentationGO:0043473850.176
regulation of neurogenesisGO:0050767870.173
female sex differentiationGO:004666040.171
positive regulation of cellular amino acid metabolic processGO:004576400.170
blood vessel developmentGO:00015682460.166
regulation of gastrulationGO:0010470240.161
protein localization to nucleusGO:003450430.154
regulation of multicellular organismal developmentGO:20000262230.154
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.152
digestive tract morphogenesisGO:00485462310.151
cellular response to external stimulusGO:007149620.146
regulation of cellular ketone metabolic processGO:001056570.146
otolith developmentGO:0048840320.136
stem cell divisionGO:001714510.128
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.126
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.123
regulation of metabolic processGO:00192223590.123
development of primary female sexual characteristicsGO:004654540.119
retinoic acid metabolic processGO:004257390.119
actin filament based movementGO:003004810.113
anterior posterior pattern specificationGO:00099521520.113
mechanoreceptor differentiationGO:0042490370.112
single organism metabolic processGO:00447102170.111
digestive tract developmentGO:00485652650.110
embryonic pectoral fin morphogenesisGO:0035118240.110
organic acid metabolic processGO:0006082310.109
single organism transportGO:00447652060.108
regulation of cellular amine metabolic processGO:003323800.107
larval developmentGO:000216420.106
pigment cell differentiationGO:0050931380.099
secondary metabolic processGO:001974830.098
regulation of cellular metabolic processGO:00313233200.097
positive regulation of erk1 and erk2 cascadeGO:007037420.097
diterpenoid biosynthetic processGO:001610270.096
carboxylic acid metabolic processGO:0019752220.093
cellular carbohydrate metabolic processGO:004426240.093
peptide transportGO:001583310.091
ear morphogenesisGO:0042471640.089
post golgi vesicle mediated transportGO:000689210.087
amine metabolic processGO:000930820.086
nephron epithelium morphogenesisGO:007208810.086
organonitrogen compound metabolic processGO:1901564740.085
cell morphogenesisGO:00009022890.084
regulation of calcium ion transportGO:005192420.084
single organism organelle organizationGO:19025891990.084
mechanosensory lateral line system developmentGO:0048881490.082
kupffer s vesicle developmentGO:0070121500.081
regulation of cell morphogenesisGO:0022604420.078
posterior lateral line neuromast primordium migrationGO:0048920120.078
response to external stimulusGO:00096052640.077
midbrain hindbrain boundary developmentGO:0030917230.076
erk1 and erk2 cascadeGO:007037140.075
regulation of retinoic acid biosynthetic processGO:190005260.075
sensory perceptionGO:0007600390.075
organelle organizationGO:00069962270.073
regulation of vitamin metabolic processGO:003065660.072
endocrine pancreas developmentGO:0031018270.072
regulation of bone remodelingGO:004685020.071
muscle cell migrationGO:001481240.071
regulation of cell differentiationGO:00455951420.071
golgi vesicle transportGO:004819330.070
positive regulation of cellular amine metabolic processGO:003324000.068
cell projection morphogenesisGO:00488582440.068
head developmentGO:00603223030.067
cellular amine metabolic processGO:004410620.067
signal transduction in absence of ligandGO:003803410.066
regulation of biosynthetic processGO:00098892500.065
positive regulation of muscle organ developmentGO:004863610.065
signal transductionGO:00071654550.064
cellular amino acid metabolic processGO:000652070.064
skeletal muscle tissue developmentGO:0007519670.063
autophagyGO:000691440.061
cellular localizationGO:0051641970.061
cerebellar granular layer morphogenesisGO:002168330.061
retinoic acid biosynthetic processGO:000213860.061
neuron projection extensionGO:1990138450.059
adult behaviorGO:003053420.059
regulation of signal transductionGO:00099662250.059
system processGO:00030081850.059
organelle localizationGO:0051640490.058
regulation of signalingGO:00230512350.058
regulation of stem cell proliferationGO:007209120.058
organic cyclic compound metabolic processGO:19013603010.057
posterior lateral line neuromast developmentGO:0048919200.056
positive regulation of cell cycleGO:004578730.056
nitrogen compound metabolic processGO:00068073190.056
cerebellar granule cell differentiationGO:002170730.055
regulation of glucose importGO:004632410.055
central nervous system developmentGO:00074173870.055
tube morphogenesisGO:00352393490.054
ion transportGO:00068111140.054
cellular nitrogen compound metabolic processGO:00346412900.054
negative regulation of signal transduction in absence of ligandGO:190109910.053
regulation of wnt signaling pathwayGO:0030111530.053
divalent inorganic cation transportGO:0072511210.053
intracellular signal transductionGO:0035556850.053
neural tube patterningGO:0021532330.052
locomotionGO:00400113130.052
cellular aromatic compound metabolic processGO:00067252950.052
adherens junction organizationGO:003433240.051
embryonic organ developmentGO:00485683810.051
cerebellar granular layer formationGO:002168430.051
negative regulation of cellular processGO:00485232830.050
amino acid transportGO:000686520.049
neuromuscular process controlling balanceGO:005088530.049
regulation of cellular carbohydrate metabolic processGO:001067540.048
cell part morphogenesisGO:00329902460.048
regulation of tissue remodelingGO:003410320.047
cell fate commitment involved in formation of primary germ layerGO:0060795260.047
detection of mechanical stimulusGO:0050982110.047
negative regulation of intracellular transportGO:003238730.047
establishment or maintenance of cell polarityGO:0007163290.047
neuron differentiationGO:00301823530.047
neurological system processGO:0050877620.046
striated muscle cell differentiationGO:00511461290.046
spindle localizationGO:0051653120.046
eye developmentGO:00016542770.046
female gonad developmentGO:000858540.046
neuroblast proliferationGO:000740520.045
purine ribonucleotide metabolic processGO:0009150270.045
otic vesicle morphogenesisGO:0071600340.045
cation transmembrane transportGO:0098655650.044
urogenital system developmentGO:0001655970.044
protein importGO:001703830.044
regulation of ion transportGO:0043269220.044
angiogenesisGO:00015251580.043
carboxylic acid biosynthetic processGO:0046394120.043
negative regulation of multicellular organismal processGO:0051241690.043
posterior lateral line developmentGO:0048916380.043
nitrogen compound transportGO:0071705230.043
melanin metabolic processGO:000658220.042
ribose phosphate metabolic processGO:0019693270.042
locus ceruleus developmentGO:002170330.042
response to nutrientGO:000758430.041
peptidyl threonine modificationGO:001821010.040
central nervous system myelinationGO:002201020.040
potassium ion transportGO:0006813100.040
negative regulation of cytoplasmic transportGO:190365020.040
camera type eye developmentGO:00430102220.039
retina development in camera type eyeGO:00600411460.039
peptidyl serine phosphorylationGO:001810510.039
blood vessel morphogenesisGO:00485142160.039
negative regulation of cell differentiationGO:0045596460.039
negative regulation of developmental processGO:0051093650.039
phagocytosisGO:000690930.039
response to organic cyclic compoundGO:0014070510.039
rhombomere 6 developmentGO:002157240.038
negative regulation of cell fate specificationGO:0009996110.038
negative regulation of protein serine threonine kinase activityGO:007190120.038
regulation of carbohydrate metabolic processGO:000610940.038
response to drugGO:004249330.037
establishment of localization in cellGO:0051649770.037
stem cell maintenanceGO:001982740.037
neuron projection developmentGO:00311751800.037
regulation of anatomical structure morphogenesisGO:00226031300.036
neuron projection morphogenesisGO:00488121610.036
positive regulation of cellular component biogenesisGO:004408930.036
negative regulation of protein phosphorylationGO:000193340.036
regulation of melanocyte differentiationGO:004563420.036
embryonic skeletal system morphogenesisGO:0048704930.036
neural tube developmentGO:0021915620.036
establishment of mitotic spindle orientationGO:0000132100.036
response to glucocorticoidGO:005138410.036
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.035
single organism cellular localizationGO:1902580460.035
establishment of cell polarityGO:0030010180.035
single organism intracellular transportGO:1902582250.035
positive regulation of transportGO:005105020.035
regulation of erk1 and erk2 cascadeGO:007037240.035
cell cycle processGO:0022402530.035
organic substance biosynthetic processGO:19015762890.034
retinoid metabolic processGO:0001523150.034
detection of mechanical stimulus involved in sensory perceptionGO:0050974110.034
organic cyclic compound biosynthetic processGO:19013622230.034
symbiosis encompassing mutualism through parasitismGO:004440340.034
regulation of organ morphogenesisGO:2000027350.033
small molecule metabolic processGO:0044281770.033
leukocyte proliferationGO:007066110.033
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.033
developmental programmed cell deathGO:001062340.033
regulation of reproductive processGO:200024140.032
cell surface receptor signaling pathwayGO:00071663250.032
regulation of isoprenoid metabolic processGO:001974760.032
sequestering of metal ionGO:005123830.032
brain developmentGO:00074202930.032
hindbrain developmentGO:0030902910.032
regulation of peptidyl tyrosine phosphorylationGO:005073010.031
production of molecular mediator of immune responseGO:000244020.031
single organism behaviorGO:0044708240.031
wnt signaling pathwayGO:0016055800.031
cartilage developmentGO:0051216960.031
positive regulation of map kinase activityGO:004340630.031
detection of external stimulusGO:0009581240.030
response to organic substanceGO:00100331530.030
mesenchymal cell proliferationGO:001046310.030
amide transportGO:0042886120.030
neuron developmentGO:00486662620.030
developmental pigmentationGO:0048066480.030
behaviorGO:0007610740.030
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.030
stem cell differentiationGO:00488631170.030
semicircular canal developmentGO:0060872240.029
positive regulation of secretion by cellGO:190353210.029
regulation of cellular biosynthetic processGO:00313262450.029
cellular response to extracellular stimulusGO:003166820.029
cellular macromolecule metabolic processGO:00442603910.029
cation transportGO:0006812810.029
response to biotic stimulusGO:0009607970.029
regulation of hormone metabolic processGO:003235060.028
homeostasis of number of cells within a tissueGO:004887340.028
ossificationGO:0001503230.028
melanocyte differentiationGO:0030318260.028
regulation of nitrogen compound metabolic processGO:00511712510.028
gastrulation with mouth forming secondGO:0001702440.028
diterpenoid metabolic processGO:0016101150.028
positive regulation of epithelial cell migrationGO:001063420.028
neuron neuron synaptic transmissionGO:000727010.028
connective tissue developmentGO:0061448990.028
response to amino acidGO:004320020.027
regulation of cell fate specificationGO:0042659200.027
transportGO:00068102200.027
monocarboxylic acid biosynthetic processGO:0072330120.027
forebrain developmentGO:0030900960.027
response to virusGO:0009615210.026
homeostatic processGO:00425921420.026
chondrocyte developmentGO:000206340.026
response to hormoneGO:0009725480.026
regulation of transmembrane transporter activityGO:002289820.026
retinal rod cell developmentGO:004654840.026
oxoacid metabolic processGO:0043436310.026
cellular biosynthetic processGO:00442492860.026
axis specificationGO:0009798430.026
cellular nitrogen compound biosynthetic processGO:00442712180.026
photoreceptor cell fate specificationGO:004370410.026
multi organism processGO:00517041340.025
skeletal system developmentGO:00015011810.025
cell junction organizationGO:0034330110.025
single organism nuclear importGO:190259330.025
rna metabolic processGO:00160702190.025
isoprenoid biosynthetic processGO:000829970.025
negative regulation of map kinase activityGO:004340720.025
cell motilityGO:00488702440.025
synaptic growth at neuromuscular junctionGO:005112420.025
hormone transportGO:000991420.025
cellular component morphogenesisGO:00329893360.025
cell growthGO:0016049570.024
embryonic appendage morphogenesisGO:0035113300.024
negative regulation of myeloid cell differentiationGO:004563810.024
cellular monovalent inorganic cation homeostasisGO:003000420.024
cell projection organizationGO:00300302840.024
peptidyl serine modificationGO:001820920.024
skeletal muscle organ developmentGO:0060538780.024
semicircular canal morphogenesisGO:0048752180.024
mesenchyme developmentGO:00604851270.024
pectoral fin developmentGO:0033339500.024
regulation of cell fate commitmentGO:0010453220.024
pancreas developmentGO:0031016840.024
regulation of gtp catabolic processGO:003312420.024
establishment of organelle localizationGO:0051656450.024
positive regulation of apoptotic signaling pathwayGO:200123510.024
gastrulationGO:00073692080.023
actin filament based processGO:0030029640.023
negative regulation of kinase activityGO:003367340.023
response to vitaminGO:003327330.023
apical junction assemblyGO:004329710.023
regulation of hormone levelsGO:0010817210.023
response to chemicalGO:00422213200.023
regulation of i kappab kinase nf kappab signalingGO:004312240.023
regulation of transporter activityGO:003240920.023
heterocycle metabolic processGO:00464832900.023
response to inorganic substanceGO:0010035380.023
protein localization to plasma membraneGO:007265910.023
tube formationGO:0035148250.023
regulation of myotube differentiationGO:001083020.023
nuclear importGO:005117030.023
dephosphorylationGO:0016311110.023
endomembrane system organizationGO:0010256130.023
regulation of developmental processGO:00507932470.023
photoreceptor cell differentiationGO:0046530550.022
cell morphogenesis involved in neuron differentiationGO:00486671630.022
intracellular transportGO:0046907320.022
cellular response to hormone stimulusGO:0032870390.022
compound eye developmentGO:004874920.022
regulation of protein phosphorylationGO:0001932180.022
organic substance transportGO:0071702580.022
heart contractionGO:0060047710.022
macromolecule biosynthetic processGO:00090592270.022
nucleic acid templated transcriptionGO:00976591810.022
nucleic acid metabolic processGO:00903042440.022
regulation of blood pressureGO:000821710.022
chemosensory behaviorGO:000763510.022
protein phosphorylationGO:0006468470.021
regulation of biological qualityGO:00650082630.021
response to ketoneGO:190165410.021
regulation of gene expressionGO:00104682650.021
neural plate anterior posterior regionalizationGO:002199980.021
negative regulation of nuclear divisionGO:005178430.021
regulation of mesodermal cell fate specificationGO:004266190.021
cellular ion homeostasisGO:0006873170.021
biosynthetic processGO:00090582940.021
myotube differentiationGO:0014902450.021
regulation of protein targetingGO:190353320.021
neuron fate specificationGO:0048665200.021
gtp catabolic processGO:000618420.020
cellular response to organic substanceGO:00713101050.020
positive regulation of secretionGO:005104710.020
negative regulation of protein kinase activityGO:000646940.020
regulation of ion transmembrane transporter activityGO:003241220.020
cell morphogenesis involved in differentiationGO:00009041950.020
positive regulation of muscle tissue developmentGO:190186310.020
regulation of sodium ion transportGO:000202820.020
response to copper ionGO:0046688130.020
response to lipidGO:0033993600.020
positive regulation of catabolic processGO:000989640.020
cellular response to nutrient levelsGO:003166920.020
liver developmentGO:0001889960.020
regulation of protein import into nucleusGO:004230620.020
somatic stem cell maintenanceGO:003501910.020
g protein coupled receptor signaling pathwayGO:0007186740.020
cytosolic calcium ion transportGO:006040130.020
positive regulation of i kappab kinase nf kappab signalingGO:004312330.020
regulation of axonogenesisGO:0050770320.020
hormone biosynthetic processGO:004244630.020
positive regulation of striated muscle cell differentiationGO:005115510.020
nucleobase containing compound metabolic processGO:00061392740.019
skeletal system morphogenesisGO:00487051020.019
regulation of protein bindingGO:004339330.019
protein import into nucleusGO:000660630.019
macromolecular complex disassemblyGO:003298410.019
cellular response to lipidGO:0071396390.019
cellular hormone metabolic processGO:0034754190.019
canonical wnt signaling pathway involved in neural crest cell differentiationGO:004433520.019
nucleocytoplasmic transportGO:000691340.019
pectoral fin morphogenesisGO:0035138290.019
response to corticosteroidGO:003196010.019
establishment of spindle localizationGO:0051293120.019
vitamin metabolic processGO:0006766110.019
ribonucleoside monophosphate catabolic processGO:000915840.019
regulation of multicellular organismal processGO:00512392770.019
membrane organizationGO:0061024210.019
positive regulation of muscle cell differentiationGO:005114910.019
response to alkaloidGO:004327920.019
pigment metabolic processGO:0042440120.019
embryonic organ morphogenesisGO:00485622740.019
sensory neuron axon guidanceGO:009737430.018
tissue homeostasisGO:0001894250.018
protein targeting to nucleusGO:004474430.018
cerebellar granular layer developmentGO:002168130.018
negative regulation of biological processGO:00485193040.018
regulation of cell projection organizationGO:0031344440.018
defense response to other organismGO:0098542330.018
muscle tissue developmentGO:00605371100.018
chemotaxisGO:00069351040.018
cytokine mediated signaling pathwayGO:001922170.018
anatomical structure homeostasisGO:0060249360.018
sensory perception of mechanical stimulusGO:0050954160.018
response to nitrogen compoundGO:1901698190.018
ion transmembrane transportGO:0034220910.018
positive regulation of exocytosisGO:004592110.018
single organism biosynthetic processGO:0044711710.018
aromatic compound biosynthetic processGO:00194382170.017
sensory perception of soundGO:000760590.017
divalent metal ion transportGO:0070838200.017
cellular component biogenesisGO:00440851780.017
small molecule biosynthetic processGO:0044283160.017
mitochondrial transportGO:000683920.017
regulation of cell developmentGO:00602841000.017
axon extension involved in axon guidanceGO:0048846100.017
cellular response to organic cyclic compoundGO:0071407380.017
pharyngeal system developmentGO:0060037180.017
regulation of rna metabolic processGO:00512522240.017
response to endogenous stimulusGO:0009719830.017
regulation of phosphorus metabolic processGO:0051174430.017
notch signaling pathwayGO:0007219350.017
regulation of cytoplasmic transportGO:190364940.017
gene expressionGO:00104672520.017
peptidyl tyrosine dephosphorylationGO:003533510.017
epidermis developmentGO:0008544480.017
protein metabolic processGO:00195381830.017
detection of mechanical stimulus involved in sensory perception of soundGO:005091030.017
regionalizationGO:00030022740.017
cell death in response to oxidative stressGO:003647320.017
membrane hyperpolarizationGO:006008110.017
regulation of apoptotic processGO:0042981980.017
negative regulation of apoptotic signaling pathwayGO:2001234100.017
tube closureGO:006060610.016
sprouting angiogenesisGO:0002040530.016
peptidyl threonine phosphorylationGO:001810710.016
cellular response to stressGO:0033554620.016
cardiac ventricle morphogenesisGO:000320870.016
exocytosisGO:000688710.016
response to steroid hormoneGO:0048545350.016
regulation of protein ubiquitinationGO:003139630.016
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.016
mitotic cell cycleGO:0000278640.016
regulation of cell growthGO:0001558290.016
negative regulation of cellular metabolic processGO:0031324770.016
regulation of nucleobase containing compound metabolic processGO:00192192500.016
odontogenesis of dentin containing toothGO:004247510.016
nuclear migrationGO:000709730.016
fin developmentGO:0033333770.016
cellular protein metabolic processGO:00442671290.016
neural crest cell migrationGO:0001755420.016
hormone secretionGO:004687920.016
dorsal ventral pattern formationGO:00099531250.016
regulation of nucleoside metabolic processGO:000911820.016
specification of axis polarityGO:006500140.016
bone remodelingGO:004684920.016
regulation of protein metabolic processGO:0051246560.016
organic acid biosynthetic processGO:0016053120.016
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.016
positive regulation of skeletal muscle tissue developmentGO:004864310.015
viral processGO:001603210.015
protein modification processGO:00362111000.015
axon developmentGO:00615641660.015
negative regulation of cellular catabolic processGO:003133030.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
guanosine containing compound catabolic processGO:190106920.015
negative regulation of blood circulationGO:190352320.015
sequestering of calcium ionGO:005120830.015
cellular response to chemical stimulusGO:00708871570.015
fin morphogenesisGO:0033334530.015
calcium ion transport into cytosolGO:006040230.015
renal system developmentGO:0072001940.015
striated muscle tissue developmentGO:00147061100.015
wnt signaling pathway planar cell polarity pathwayGO:006007140.015
response to uvGO:000941130.015
regulation of endodermal cell differentiationGO:1903224150.015
neurotransmitter transportGO:000683620.015
kidney developmentGO:0001822920.015
transmission of nerve impulseGO:0019226190.015
phosphate containing compound metabolic processGO:00067961080.015
carbohydrate derivative biosynthetic processGO:1901137430.015
positive regulation of striated muscle tissue developmentGO:004584410.014
regulation of protein transportGO:005122330.014
chordate embryonic developmentGO:00430092710.014
developmental growth involved in morphogenesisGO:0060560860.014
regulation of establishment of planar polarityGO:009017540.014
otic vesicle developmentGO:0071599420.014
guanosine containing compound metabolic processGO:190106840.014
type b pancreatic cell proliferationGO:004434210.014
regulation of intracellular protein transportGO:003315730.014
regulation of epithelial cell proliferationGO:005067830.014
canonical wnt signaling pathwayGO:0060070480.014
periodic partitioningGO:000736510.014
cellular response to fibroblast growth factor stimulusGO:0044344220.014
cellular protein modification processGO:00064641000.014
rostrocaudal neural tube patterningGO:0021903290.014
regulation of collateral sprouting in absence of injuryGO:004869640.014
monoamine transportGO:001584410.014
programmed cell deathGO:00125011190.014
adenohypophysis developmentGO:0021984150.014
negative regulation of neutrophil chemotaxisGO:009002430.014
cerebellum morphogenesisGO:0021587100.014

hmx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.224
disease of anatomical entityDOID:700.224
auditory system diseaseDOID:274200.224
sensory system diseaseDOID:005015500.224
autosomal dominant nonsyndromic deafnessDOID:005056400.224
nonsyndromic deafnessDOID:005056300.224
organ system cancerDOID:005068600.027
disease of cellular proliferationDOID:1456600.027
cancerDOID:16200.027
musculoskeletal system diseaseDOID:1700.026
muscular diseaseDOID:008000000.026