Danio rerio

45 known processes

kcnh2

potassium voltage-gated channel, subfamily H (eag-related), member 2

(Aliases: erg)

kcnh2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550851200.759
hematopoietic or lymphoid organ developmentGO:00485341910.664
cation transmembrane transportGO:0098655650.581
immune system processGO:00023762410.564
regulation of multicellular organismal processGO:00512392770.471
immune system developmentGO:00025201910.464
hemopoiesisGO:00300971830.428
inorganic ion transmembrane transportGO:0098660570.415
cellular component movementGO:00069283350.370
circulatory system processGO:0003013870.359
inorganic cation transmembrane transportGO:0098662500.352
ion transmembrane transportGO:0034220910.339
membrane repolarizationGO:008600920.325
embryonic hemopoiesisGO:0035162530.320
metal ion transportGO:0030001580.317
embryonic organ developmentGO:00485683810.256
homeostasis of number of cellsGO:0048872620.256
regulation of muscle contractionGO:000693730.251
Worm
skeletal system developmentGO:00015011810.236
single organism transportGO:00447652060.221
single organism localizationGO:19025782250.210
erythrocyte homeostasisGO:0034101550.202
ion homeostasisGO:0050801410.200
ion transportGO:00068111140.196
heart processGO:0003015710.191
cell projection organizationGO:00300302840.186
homeostatic processGO:00425921420.179
regulation of blood circulationGO:1903522320.178
skeletal muscle tissue developmentGO:0007519670.163
response to drugGO:004249330.159
blood circulationGO:0008015870.159
regulation of response to stimulusGO:00485832690.156
heart contractionGO:0060047710.154
regulation of transmembrane transportGO:0034762180.151
larval developmentGO:000216420.148
regulation of biological qualityGO:00650082630.134
regulation of organ growthGO:004662030.133
system processGO:00030081850.133
regulation of bindingGO:005109830.131
myeloid cell homeostasisGO:0002262560.130
myeloid cell differentiationGO:0030099860.125
axon developmentGO:00615641660.125
vasculature developmentGO:00019442780.120
regulation of system processGO:0044057400.117
calcium ion importGO:007050940.117
striated muscle contractionGO:0006941120.116
regulation of tube sizeGO:003515020.112
specification of symmetryGO:00097992040.111
cation transportGO:0006812810.109
establishment of localizationGO:00512342440.092
negative regulation of cellular processGO:00485232830.092
muscle cell differentiationGO:00426921390.091
regulation of ion transportGO:0043269220.089
regulation of heart growthGO:006042020.089
nitric oxide biosynthetic processGO:000680920.086
myofibril assemblyGO:0030239480.085
generation of neuronsGO:00486993850.084
regulation of protein bindingGO:004339330.083
protein localization to nucleusGO:003450430.082
post embryonic morphogenesisGO:000988640.081
chordate embryonic developmentGO:00430092710.081
leukocyte proliferationGO:007066110.080
muscle system processGO:0003012200.078
Worm
cell part morphogenesisGO:00329902460.076
cell morphogenesisGO:00009022890.076
neuromast developmentGO:0048884460.076
microtubule organizing center organizationGO:003102310.075
embryo development ending in birth or egg hatchingGO:00097922710.074
protein import into nucleusGO:000660630.072
nitric oxide metabolic processGO:004620920.071
neuron differentiationGO:00301823530.069
muscle organ developmentGO:00075171010.069
sensory system developmentGO:0048880760.065
photoreceptor cell fate specificationGO:004370410.065
calcium ion transmembrane transportGO:0070588130.065
regulation of transportGO:0051049450.064
cell surface receptor signaling pathwayGO:00071663250.064
response to stressGO:00069502630.064
mitochondrion organizationGO:000700540.063
positive regulation of cytokine productionGO:000181920.063
locomotionGO:00400113130.063
Worm
ear developmentGO:00435831270.063
lymphocyte homeostasisGO:000226010.062
regulation of multicellular organism growthGO:004001440.062
heart developmentGO:00075073130.061
response to glucocorticoidGO:005138410.060
primitive hemopoiesisGO:0060215270.060
cation homeostasisGO:0055080330.059
heterocycle metabolic processGO:00464832900.059
cellular component morphogenesisGO:00329893360.059
cellular amide metabolic processGO:004360340.058
reactive nitrogen species metabolic processGO:200105700.058
multicellular organism growthGO:003526440.058
macroautophagyGO:001623610.057
response to other organismGO:0051707970.057
protein importGO:001703830.056
protein targeting to nucleusGO:004474430.056
regulation of reactive oxygen species metabolic processGO:200037720.056
nucleobase containing compound metabolic processGO:00061392740.056
erythrocyte differentiationGO:0030218540.055
response to organic substanceGO:00100331530.055
proteolysis involved in cellular protein catabolic processGO:005160330.055
growth plate cartilage morphogenesisGO:000342210.055
determination of left right symmetryGO:00073681790.055
blood vessel developmentGO:00015682460.055
skeletal system morphogenesisGO:00487051020.054
agingGO:000756820.052
ventricular cardiac muscle tissue morphogenesisGO:005501020.052
post embryonic organ developmentGO:004856940.052
protein heterooligomerizationGO:005129110.051
positive regulation of transportGO:005105020.051
nucleocytoplasmic transportGO:000691340.050
organic cyclic compound metabolic processGO:19013603010.050
muscle tissue developmentGO:00605371100.049
activation of immune responseGO:000225390.049
nuclear importGO:005117030.049
appendage morphogenesisGO:0035107560.049
heart morphogenesisGO:00030071560.049
positive regulation of striated muscle tissue developmentGO:004584410.048
metal ion homeostasisGO:0055065260.048
heart loopingGO:0001947940.048
centrosome organizationGO:005129710.048
response to biotic stimulusGO:0009607970.048
regulation of production of molecular mediator of immune responseGO:000270010.047
mononuclear cell proliferationGO:003294310.047
appendage developmentGO:0048736800.047
organelle assemblyGO:00709251100.047
signal transductionGO:00071654550.046
digestive tract developmentGO:00485652650.046
regulation of anatomical structure morphogenesisGO:00226031300.046
sensory organ developmentGO:00074233930.046
extracellular matrix organizationGO:0030198270.046
positive regulation of cellular component biogenesisGO:004408930.046
response to chemicalGO:00422213200.045
negative regulation of cellular catabolic processGO:003133030.045
response to fluid shear stressGO:003440520.045
neurological system processGO:0050877620.045
Fly
cell morphogenesis involved in neuron differentiationGO:00486671630.045
positive regulation of cell cycleGO:004578730.044
single organism nuclear importGO:190259330.044
cell migrationGO:00164772370.044
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.044
hematopoietic stem cell differentiationGO:0060218200.043
regulation of signal transductionGO:00099662250.043
renal system developmentGO:0072001940.043
regulation of cytokine productionGO:000181730.043
stem cell divisionGO:001714510.043
growthGO:00400071740.042
chemical homeostasisGO:0048878490.042
response to corticosteroidGO:003196010.042
embryonic skeletal system morphogenesisGO:0048704930.042
nucleoside monophosphate catabolic processGO:000912540.042
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.042
regulation of blood vessel sizeGO:005088020.041
regulation of reproductive processGO:200024140.040
pericardium developmentGO:006003910.040
regulation of primary metabolic processGO:00800903110.040
determination of bilateral symmetryGO:00098552040.040
nitrogen compound metabolic processGO:00068073190.040
multi organism reproductive processGO:0044703360.040
Worm
regulation of molecular functionGO:0065009700.040
positive regulation of biological processGO:00485182530.040
cellular response to chemical stimulusGO:00708871570.040
extracellular structure organizationGO:0043062270.039
regulation of photoreceptor cell differentiationGO:004653220.039
striated muscle tissue developmentGO:00147061100.039
maintenance of locationGO:005123540.039
fin morphogenesisGO:0033334530.039
response to abiotic stimulusGO:00096281220.039
positive regulation of muscle tissue developmentGO:190186310.039
cellular response to starvationGO:000926710.039
wnt signaling pathwayGO:0016055800.039
fin developmentGO:0033333770.038
response to bacteriumGO:0009617580.038
regulation of receptor activityGO:001046920.038
ventricular cardiac muscle tissue developmentGO:000322930.038
regulation of multicellular organismal developmentGO:20000262230.038
multi organism processGO:00517041340.038
Worm
cell substrate adhesionGO:003158940.037
transcription from rna polymerase ii promoterGO:0006366800.037
cell morphogenesis involved in differentiationGO:00009041950.037
embryonic heart tube morphogenesisGO:00031431080.037
negative regulation of autophagyGO:001050710.037
cellular protein catabolic processGO:004425740.037
developmental growthGO:00485891660.037
central nervous system developmentGO:00074173870.037
regulation of metal ion transportGO:001095940.037
neuron projection morphogenesisGO:00488121610.036
response to alkaloidGO:004327920.036
regulation of epithelial cell proliferationGO:005067830.036
regulation of protein transportGO:005122330.036
amine metabolic processGO:000930820.035
blood vessel morphogenesisGO:00485142160.035
regulation of cell communicationGO:00106462320.035
antimicrobial humoral responseGO:001973020.035
response to external stimulusGO:00096052640.035
muscle cell developmentGO:00550011150.035
regulation of transcription from rna polymerase ii promoterGO:00063571140.035
regulation of cell shapeGO:000836010.035
neuromuscular process controlling balanceGO:005088530.035
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.035
organelle organizationGO:00069962270.035
cellular nitrogen compound metabolic processGO:00346412900.034
striated muscle cell developmentGO:00550021080.034
striated muscle cell differentiationGO:00511461290.034
reactive oxygen species metabolic processGO:007259360.034
pronephros developmentGO:0048793690.034
regulation of ion transmembrane transportGO:0034765180.034
leukocyte homeostasisGO:000177620.034
somatic muscle developmentGO:000752540.034
regulation of circadian sleep wake cycle sleepGO:004518710.034
regulation of hormone secretionGO:004688320.033
androgen metabolic processGO:000820920.033
positive regulation of map kinase activityGO:004340630.033
enzyme linked receptor protein signaling pathwayGO:00071671060.033
regulation of autophagyGO:001050630.032
regulation of cellular amine metabolic processGO:003323800.032
regulation of jak stat cascadeGO:004642530.032
fertilizationGO:000956630.032
circadian sleep wake cycle sleepGO:005080210.032
nuclear transportGO:005116940.032
tube morphogenesisGO:00352393490.031
regulation of peptidyl tyrosine phosphorylationGO:005073010.031
cellular response to external stimulusGO:007149620.031
cell motilityGO:00488702440.031
columnar cuboidal epithelial cell differentiationGO:0002065380.031
embryonic skeletal system developmentGO:0048706970.031
muscle structure developmentGO:00610611960.031
regulation of protein catabolic processGO:004217610.031
muscle fiber developmentGO:0048747520.031
regulation of circadian sleep wake cycleGO:004274910.031
regulation of circadian rhythmGO:004275240.030
reactive oxygen species biosynthetic processGO:190340910.030
b cell activationGO:004211320.030
regulation of vascular endothelial growth factor receptor signaling pathwayGO:003094780.030
atrioventricular valve formationGO:000319030.030
cell projection morphogenesisGO:00488582440.030
determination of heart left right asymmetryGO:00613711170.030
heart valve formationGO:000318840.029
regulation of protein ubiquitinationGO:003139630.029
tissue remodelingGO:004877140.029
muscle contractionGO:0006936180.029
Worm
nuclear exportGO:005116810.029
lateral line system developmentGO:0048925760.029
establishment of protein localization to organelleGO:007259440.029
regulation of developmental processGO:00507932470.029
regulation of cellular amino acid metabolic processGO:000652100.029
eye developmentGO:00016542770.029
positive regulation of muscle organ developmentGO:004863610.029
convergent extensionGO:00600261180.028
actomyosin structure organizationGO:0031032530.028
immune responseGO:0006955280.028
erythrocyte maturationGO:004324980.028
anterior posterior pattern specificationGO:00099521520.028
positive regulation of cellular amino acid metabolic processGO:004576400.028
regulation of protein localization to nucleusGO:190018020.028
peptide metabolic processGO:000651810.028
regulation of dna templated transcription elongationGO:003278430.028
regulation of protein modification by small protein conjugation or removalGO:190332030.027
morphogenesis of an epitheliumGO:00020093330.027
protein secretionGO:000930610.027
lymphocyte proliferationGO:004665110.027
centrosome cycleGO:000709810.027
macromolecule catabolic processGO:0009057150.027
Worm
deathGO:00162651210.027
regulation of response to nutrient levelsGO:003210710.027
positive regulation of neuron apoptotic processGO:004352510.027
stem cell proliferationGO:007208940.027
atp catabolic processGO:000620040.026
positive regulation of secretionGO:005104710.026
apoptotic process involved in developmentGO:190274220.026
positive regulation of secretion by cellGO:190353210.026
positive regulation of cellular processGO:00485222010.026
lateral line developmentGO:0048882660.026
cellular component assemblyGO:00226071700.026
cellular component biogenesisGO:00440851780.026
neuroepithelial cell differentiationGO:0060563260.026
positive regulation of cytosolic calcium ion concentrationGO:000720440.026
regulation of blood pressureGO:000821710.026
regulation of cardiac muscle contractionGO:005511720.026
regulation of immune responseGO:0050776140.026
cellular response to molecule of bacterial originGO:007121930.026
autophagyGO:000691440.026
regulation of anatomical structure sizeGO:0090066330.026
regulation of protein complex assemblyGO:004325430.026
negative regulation of developmental processGO:0051093650.026
embryonic heart tube developmentGO:00350501330.025
axon guidanceGO:0007411860.025
connective tissue developmentGO:0061448990.025
outflow tract morphogenesisGO:000315110.025
transportGO:00068102200.025
positive regulation of striated muscle cell differentiationGO:005115510.025
cellular amine metabolic processGO:004410620.025
regulation of cellular ketone metabolic processGO:001056570.025
embryonic organ morphogenesisGO:00485622740.025
symbiosis encompassing mutualism through parasitismGO:004440340.025
regulation of immune system processGO:0002682340.025
female sex differentiationGO:004666040.025
regulation of synaptic plasticityGO:004816710.025
inner ear developmentGO:00488391260.025
regulation of cellular metabolic processGO:00313233200.024
positive regulation of immune system processGO:0002684170.024
hematopoietic progenitor cell differentiationGO:0002244230.024
regulation of protein import into nucleusGO:004230620.024
alpha amino acid metabolic processGO:190160530.024
angiogenesisGO:00015251580.024
modification of morphology or physiology of other organismGO:003582140.024
proepicardium developmentGO:000334240.024
positive regulation of immune responseGO:0050778110.024
production of molecular mediator of immune responseGO:000244020.024
single organism organelle organizationGO:19025891990.024
pigmentationGO:0043473850.024
negative regulation of biological processGO:00485193040.024
interaction with hostGO:005170140.023
pancreas developmentGO:0031016840.023
positive regulation of immune effector processGO:000269930.023
synaptic transmission cholinergicGO:000727140.023
carbohydrate homeostasisGO:003350010.023
cellular biosynthetic processGO:00442492860.023
developmental programmed cell deathGO:001062340.023
cell cycle arrestGO:000705010.023
response to woundingGO:00096111160.023
response to external biotic stimulusGO:0043207970.023
insulin like growth factor receptor signaling pathwayGO:004800940.023
regulation of behaviorGO:0050795240.022
regulation of neuron differentiationGO:0045664560.022
cellular response to nutrient levelsGO:003166920.022
regulation of locomotionGO:0040012550.022
endochondral bone morphogenesisGO:006035080.022
cartilage condensationGO:000150230.022
cell cycle g1 s phase transitionGO:004484310.022
positive regulation of multicellular organismal processGO:0051240520.022
caudal fin morphogenesisGO:003514370.022
membrane lipid biosynthetic processGO:004646720.022
single organism metabolic processGO:00447102170.021
localization of cellGO:00516742440.021
negative regulation of protein transportGO:005122430.021
positive regulation of blood circulationGO:190352420.021
regulation of heart contractionGO:0008016320.021
olfactory bulb developmentGO:002177240.021
regulation of signalingGO:00230512350.021
cardiac atrium morphogenesisGO:000320920.021
neuron developmentGO:00486662620.021
modulation by virus of host morphology or physiologyGO:001904810.021
stem cell maintenanceGO:001982740.021
carboxylic acid metabolic processGO:0019752220.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.021
multi organism cellular processGO:004476420.021
regulation of striated muscle contractionGO:000694220.021
reciprocal dna recombinationGO:003582510.021
proteasomal protein catabolic processGO:001049820.021
notochord developmentGO:0030903540.021
nephron tubule morphogenesisGO:007207810.021
response to organic cyclic compoundGO:0014070510.020
regulation of establishment of protein localizationGO:007020140.020
regulation of biomineral tissue developmentGO:007016720.020
response to glucoseGO:000974930.020
glucose homeostasisGO:004259310.020
regulation of skeletal muscle fiber developmentGO:004874220.020
lipid storageGO:001991510.020
somitogenesisGO:0001756870.020
stem cell differentiationGO:00488631170.020
immune response activating signal transductionGO:000275750.020
cellular nitrogen compound biosynthetic processGO:00442712180.020
post embryonic organ morphogenesisGO:004856310.020
positive regulation of neuron deathGO:190121610.020
ribonucleoside monophosphate catabolic processGO:000915840.020
sleepGO:003043110.020
phosphate containing compound metabolic processGO:00067961080.020
fatty acid biosynthetic processGO:000663340.020
cellular response to hypoxiaGO:007145610.020
cardiac ventricle morphogenesisGO:000320870.020
organic cyclic compound biosynthetic processGO:19013622230.020
heart valve morphogenesisGO:000317980.020
negative regulation of response to stimulusGO:00485851040.019
endothelial cell differentiationGO:0045446200.019
regulation of growthGO:0040008420.019
muscle hypertrophyGO:001489620.019
b cell differentiationGO:003018310.019
cellular response to extracellular stimulusGO:003166820.019
cellular response to growth factor stimulusGO:0071363390.019
purine ribonucleoside monophosphate catabolic processGO:000916940.019
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.019
regulation of erythrocyte differentiationGO:004564620.019
regulation of skeletal muscle tissue developmentGO:004864140.019
cellular response to organic substanceGO:00713101050.019
head developmentGO:00603223030.019
septum transversum developmentGO:000334340.019
positive regulation of heart contractionGO:004582320.019
protein complex assemblyGO:0006461300.019
odontogenesis of dentin containing toothGO:004247510.019
cellular response to endogenous stimulusGO:0071495680.019
cell deathGO:00082191210.019
positive regulation of cell activationGO:005086710.019
kidney developmentGO:0001822920.019
cellular localizationGO:0051641970.019
myeloid leukocyte differentiationGO:0002573150.019
regulation of response to extracellular stimulusGO:003210410.019
bone morphogenesisGO:0060349110.018
reproductionGO:0000003400.018
Worm
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.018
regulation of metabolic processGO:00192223590.018
protein acetylationGO:000647320.018
pharyngeal muscle developmentGO:004328240.018
digestive tract morphogenesisGO:00485462310.018
cellular response to oxygen levelsGO:007145310.018
hormone biosynthetic processGO:004244630.018
positive regulation of cellular amine metabolic processGO:003324000.018
cardiac muscle tissue morphogenesisGO:005500870.018
leukocyte differentiationGO:0002521250.018
ossificationGO:0001503230.018
negative regulation of signal transductionGO:0009968940.018
positive regulation of signal transductionGO:0009967560.018
regulation of intracellular protein transportGO:003315730.018
calcium ion transportGO:0006816180.018
actin filament based movementGO:003004810.018
g1 s transition of mitotic cell cycleGO:000008210.018
regulation of cellular protein catabolic processGO:190336210.017
melanocyte differentiationGO:0030318260.017
negative regulation of cell communicationGO:0010648960.017
response to uvGO:000941130.017
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.017
regulation of cell proliferation involved in heart morphogenesisGO:200013620.017
heterocycle biosynthetic processGO:00181302150.017
somite developmentGO:0061053960.017
organonitrogen compound metabolic processGO:1901564740.017
positive regulation of catabolic processGO:000989640.017
urogenital system developmentGO:0001655970.017
ameboidal type cell migrationGO:00016671430.017
positive regulation of carbohydrate metabolic processGO:004591310.017
regenerationGO:0031099910.017
endochondral bone growthGO:000341620.017
negative regulation of bmp signaling pathwayGO:0030514130.017
regulation of cytoplasmic transportGO:190364940.017
phagocytosisGO:000690930.017
cellular response to lipopolysaccharideGO:007122230.017
embryonic viscerocranium morphogenesisGO:0048703520.017
hormone transportGO:000991420.017
viral processGO:001603210.017
cellular macromolecule metabolic processGO:00442603910.017
modification by symbiont of host morphology or physiologyGO:004400340.017
purine nucleoside monophosphate catabolic processGO:000912840.016
regulation of dna templated transcription in response to stressGO:004362000.016
monocyte differentiationGO:003022420.016
positive regulation of epithelial cell migrationGO:001063420.016
mechanosensory lateral line system developmentGO:0048881490.016
biological adhesionGO:0022610400.016
photoreceptor cell fate commitmentGO:004655210.016
glucose importGO:004632320.016
positive regulation of biosynthetic processGO:0009891680.016
cellular response to biotic stimulusGO:007121630.016
embryonic cranial skeleton morphogenesisGO:0048701900.016
erythrocyte developmentGO:0048821240.016
oxoacid metabolic processGO:0043436310.016
response to antibioticGO:004667710.016
gastrulationGO:00073692080.016
heart valve developmentGO:0003170140.016
regulation of nitrogen compound metabolic processGO:00511712510.016
neuron fate determinationGO:004866420.016
cardiac muscle tissue developmentGO:0048738480.016
regulation of cellular component organizationGO:0051128860.016
negative regulation of epithelial cell proliferationGO:005068010.016
meiosis iGO:000712710.016
regulation of transporter activityGO:003240920.016
negative regulation of cytokine productionGO:000181810.016
actin cytoskeleton organizationGO:0030036630.016
inositol lipid mediated signalingGO:004801720.016
regulation of neurogenesisGO:0050767870.016
response to monosaccharideGO:003428430.016
negative regulation of protein phosphorylationGO:000193340.016
response to hexoseGO:000974630.016
response to ketoneGO:190165410.016
positive regulation of protein complex assemblyGO:003133420.015
cellular ketone metabolic processGO:0042180110.015
smooth muscle contractionGO:000693920.015
oocyte maturationGO:000155640.015
camera type eye developmentGO:00430102220.015
cell proliferationGO:0008283800.015
small molecule metabolic processGO:0044281770.015
biosynthetic processGO:00090582940.015
cognitionGO:005089010.015
nephron morphogenesisGO:007202820.015
signal transduction in absence of ligandGO:003803410.015
regulation of cell activationGO:005086510.015

kcnh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.099
disease of metabolismDOID:001466700.057
musculoskeletal system diseaseDOID:1700.036
muscular diseaseDOID:008000000.032
muscle tissue diseaseDOID:6600.032
cardiovascular system diseaseDOID:128700.025
inherited metabolic disorderDOID:65500.025
nervous system diseaseDOID:86300.019
central nervous system diseaseDOID:33100.018
neurodegenerative diseaseDOID:128900.018
disease of cellular proliferationDOID:1456600.017