Danio rerio

106 known processes

mcl1a

myeloid cell leukemia sequence 1a

(Aliases: wu:fb70a08,zgc:109835,zfMLP1,wu:fb72f02,fb72f02,zfMcl-1a)

mcl1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of mitosisGO:004583930.719
positive regulation of cell deathGO:0010942290.691
Human Zebrafish Mouse
regulation of extrinsic apoptotic signaling pathwayGO:200123630.683
Human
response to transition metal nanoparticleGO:1990267280.637
Zebrafish
organelle fusionGO:004828430.624
Worm
response to cadmium ionGO:0046686140.610
Zebrafish
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.583
Zebrafish
chordate embryonic developmentGO:00430092710.576
single organism membrane fusionGO:004480120.576
Worm
gene expressionGO:00104672520.548
positive regulation of neuron apoptotic processGO:004352510.533
Human Mouse
positive regulation of biological processGO:00485182530.518
Human Zebrafish Mouse Worm
regulation of mitochondrion organizationGO:001082110.512
Worm
regulation of developmental processGO:00507932470.505
Worm
regulation of primary metabolic processGO:00800903110.431
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.426
Human Mouse
regulation of cell communicationGO:00106462320.406
Human Zebrafish Mouse
positive regulation of transportGO:005105020.398
response to organic substanceGO:00100331530.381
Human Zebrafish
mitochondrion organizationGO:000700540.370
Mouse Worm
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.363
Human
regulation of signalingGO:00230512350.357
Human Zebrafish Mouse
positive regulation of neuron deathGO:190121610.334
Human Mouse
regulation of apoptotic processGO:0042981980.330
negative regulation of intrinsic apoptotic signaling pathwayGO:200124380.330
Zebrafish
response to stressGO:00069502630.329
Human Mouse
positive regulation of apoptotic signaling pathwayGO:200123510.328
Human Mouse
apoptotic processGO:00069151160.326
organic cyclic compound metabolic processGO:19013603010.325
Worm
regulation of cell deathGO:00109411030.308
programmed cell deathGO:00125011190.306
negative regulation of biological processGO:00485193040.302
regulation of rna biosynthetic processGO:20011412130.301
response to chemicalGO:00422213200.298
Human Zebrafish Mouse
cellular macromolecule metabolic processGO:00442603910.294
negative regulation of cellular processGO:00485232830.286
negative regulation of gene expressionGO:0010629650.281
gland developmentGO:00487321430.279
Zebrafish
regulation of nitrogen compound metabolic processGO:00511712510.278
Worm
regulation of cellular response to oxidative stressGO:190040720.272
Human Mouse
signal transduction in absence of ligandGO:003803410.268
Human Mouse
regulation of gene expressionGO:00104682650.259
positive regulation of gtp catabolic processGO:003312610.257
Worm
response to metal ionGO:0010038340.253
Zebrafish
regulation of cell cycleGO:0051726520.250
heterocycle metabolic processGO:00464832900.247
Worm
cellular amide metabolic processGO:004360340.240
cellular aromatic compound metabolic processGO:00067252950.237
Worm
positive regulation of apoptotic processGO:0043065290.236
Human Zebrafish Mouse
signal transductionGO:00071654550.232
Human Zebrafish Mouse
regulation of protein import into nucleusGO:004230620.228
cell surface receptor signaling pathwayGO:00071663250.227
Human Mouse
extrinsic apoptotic signaling pathwayGO:009719130.221
Human Mouse
negative regulation of signalingGO:0023057960.219
Human Zebrafish
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.214
Human Mouse
negative regulation of nuclear divisionGO:005178430.207
embryo development ending in birth or egg hatchingGO:00097922710.206
deathGO:00162651210.206
regulation of metabolic processGO:00192223590.204
regulation of response to oxidative stressGO:190288220.203
Human Mouse
response to inorganic substanceGO:0010035380.200
Zebrafish
regulation of programmed cell deathGO:00430671010.200
establishment of localizationGO:00512342440.196
regulation of protein localization to nucleusGO:190018020.188
negative regulation of proteolysisGO:0045861100.187
homeostatic processGO:00425921420.183
cell deathGO:00082191210.182
regulation of protein targetingGO:190353320.175
modulation by virus of host morphology or physiologyGO:001904810.174
cellular nitrogen compound metabolic processGO:00346412900.169
Worm
positive regulation of cellular processGO:00485222010.164
Human Zebrafish Mouse Worm
negative regulation of signal transduction in absence of ligandGO:190109910.164
Human
regulation of biological qualityGO:00650082630.163
regulation of cellular metabolic processGO:00313233200.162
regulation of gtp catabolic processGO:003312420.161
Worm
immune system developmentGO:00025201910.161
positive regulation of cell killingGO:003134320.161
negative regulation of cell communicationGO:0010648960.156
Human Zebrafish
thyroid gland developmentGO:0030878120.156
Zebrafish
protein metabolic processGO:00195381830.155
regulation of nucleotide catabolic processGO:003081120.154
Worm
establishment of protein localization to organelleGO:007259440.154
nitrogen compound metabolic processGO:00068073190.152
Worm
regulation of nucleoside metabolic processGO:000911820.150
Worm
positive regulation of cellular metabolic processGO:0031325940.150
Zebrafish Worm
negative regulation of cysteine type endopeptidase activityGO:200011780.150
regulation of cysteine type endopeptidase activityGO:2000116210.148
nuclear importGO:005117030.148
protein targeting to nucleusGO:004474430.146
nucleocytoplasmic transportGO:000691340.146
regulation of macromolecule metabolic processGO:00602553170.143
negative regulation of response to stimulusGO:00485851040.143
Human Zebrafish
negative regulation of metabolic processGO:0009892860.142
regulation of establishment of protein localizationGO:007020140.140
hematopoietic or lymphoid organ developmentGO:00485341910.139
gtp catabolic processGO:000618420.138
Worm
positive regulation of metabolic processGO:00098931080.137
Zebrafish Worm
positive regulation of cellular catabolic processGO:003133130.135
Worm
positive regulation of cysteine type endopeptidase activityGO:2001056100.133
Zebrafish
single organism nuclear importGO:190259330.128
guanosine containing compound catabolic processGO:190106920.125
Worm
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.122
embryonic organ developmentGO:00485683810.121
positive regulation of macromolecule metabolic processGO:0010604930.120
Zebrafish
cell death in response to oxidative stressGO:003647320.118
Human Mouse
nucleobase containing compound biosynthetic processGO:00346542050.117
positive regulation of purine nucleotide catabolic processGO:003312310.115
Worm
regulation of response to stimulusGO:00485832690.115
Human Zebrafish Mouse
cellular protein metabolic processGO:00442671290.114
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.113
Human
regulation of cytokine productionGO:000181730.109
gtp metabolic processGO:004603940.109
Worm
negative regulation of protein processingGO:0010955100.108
interaction with hostGO:005170140.108
negative regulation of protein phosphorylationGO:000193340.108
positive regulation of programmed cell deathGO:0043068290.107
Human Zebrafish Mouse
mitotic nuclear divisionGO:0007067180.105
regulation of protein metabolic processGO:0051246560.105
cellular response to stressGO:0033554620.103
Human Mouse
regulation of signal transductionGO:00099662250.102
Human Zebrafish Mouse
regulation of protein transportGO:005122330.101
cellular response to external stimulusGO:007149620.100
amide transportGO:0042886120.100
regulation of nucleocytoplasmic transportGO:004682220.099
organonitrogen compound metabolic processGO:1901564740.098
Worm
aromatic compound biosynthetic processGO:00194382170.096
killing of cells in other organism involved in symbiotic interactionGO:005188310.094
positive regulation of developmental processGO:0051094500.092
Worm
protein complex localizationGO:003150310.091
regulation of endopeptidase activityGO:0052548230.090
regulation of cytoplasmic transportGO:190364940.090
single organism transportGO:00447652060.090
response to biotic stimulusGO:0009607970.090
membrane fusionGO:006102520.089
Worm
cellular response to chemical stimulusGO:00708871570.088
Human Mouse
renal system developmentGO:0072001940.083
kidney developmentGO:0001822920.082
apoptotic process involved in developmentGO:190274220.081
positive regulation of gtpase activityGO:004354710.079
Worm
cellular response to dna damage stimulusGO:0006974240.078
Human Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.078
Worm
single organism metabolic processGO:00447102170.076
Worm
mitotic cell cycle processGO:1903047480.076
regulation of metal ion transportGO:001095940.076
response to drugGO:004249330.076
regulation of cellular biosynthetic processGO:00313262450.076
protein importGO:001703830.075
mitochondrion morphogenesisGO:007058420.074
response to virusGO:0009615210.074
positive regulation of protein metabolic processGO:0051247230.074
Zebrafish
mitotic cell cycleGO:0000278640.073
protein localization to nucleusGO:003450430.072
axon regenerationGO:0031103140.071
nucleic acid templated transcriptionGO:00976591810.071
negative regulation of protein transportGO:005122430.071
organic substance biosynthetic processGO:19015762890.070
organelle organizationGO:00069962270.070
organic substance transportGO:0071702580.070
regulation of cell differentiationGO:00455951420.069
response to methylmercuryGO:0051597110.069
Zebrafish
regulation of protein maturationGO:1903317100.069
regulation of cellular component organizationGO:0051128860.068
female sex differentiationGO:004666040.068
maintenance of locationGO:005123540.068
positive regulation of catabolic processGO:000989640.067
Worm
regulation of peptidase activityGO:0052547230.067
negative regulation of hydrolase activityGO:0051346100.067
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.067
Human
regulation of multicellular organismal processGO:00512392770.066
positive regulation of nucleobase containing compound metabolic processGO:0045935690.065
Worm
regulation of transcription from rna polymerase ii promoterGO:00063571140.065
regulation of cellular macromolecule biosynthetic processGO:20001122220.064
negative regulation of cytoplasmic transportGO:190365020.064
tube morphogenesisGO:00352393490.064
nuclear transportGO:005116940.063
negative regulation of protein localization to nucleusGO:190018120.063
transcription dna templatedGO:00063511810.063
phosphate containing compound metabolic processGO:00067961080.063
Worm
cellular nitrogen compound biosynthetic processGO:00442712180.063
negative regulation of response to cytokine stimulusGO:006076120.062
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.062
developmental programmed cell deathGO:001062340.061
purine nucleotide metabolic processGO:0006163270.060
Worm
response to external stimulusGO:00096052640.059
modification by symbiont of host morphology or physiologyGO:004400340.059
negative regulation of cell divisionGO:005178240.058
positive regulation of nitrogen compound metabolic processGO:0051173690.058
Worm
defense responseGO:0006952470.058
negative regulation of protein maturationGO:1903318100.058
multicellular organism growthGO:003526440.058
regulation of macromolecule biosynthetic processGO:00105562250.057
protein import into nucleusGO:000660630.056
transportGO:00068102200.056
regulation of gtpase activityGO:004308720.056
Worm
negative regulation of i kappab kinase nf kappab signalingGO:004312410.056
positive regulation of jnk cascadeGO:004633030.055
agingGO:000756820.055
peptide transportGO:001583310.055
cellular biosynthetic processGO:00442492860.055
heterocycle biosynthetic processGO:00181302150.055
brain developmentGO:00074202930.055
peptide metabolic processGO:000651810.055
regulation of synaptic plasticityGO:004816710.054
macromolecule biosynthetic processGO:00090592270.054
response to nutrientGO:000758430.053
neuron deathGO:0070997210.053
Human Mouse
nik nf kappab signalingGO:003806110.053
response to external biotic stimulusGO:0043207970.052
cellular response to radiationGO:007147840.052
regulation of intracellular protein transportGO:003315730.052
single organism membrane organizationGO:0044802200.051
Worm
regulation of response to interferon gammaGO:006033010.051
regulation of multicellular organism growthGO:004001440.050
regulation of organ growthGO:004662030.050
regulation of rna metabolic processGO:00512522240.050
apoptotic process involved in morphogenesisGO:006056120.050
positive regulation of molecular functionGO:0044093330.050
Zebrafish Worm
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315470.050
positive regulation of endopeptidase activityGO:0010950100.049
Zebrafish
negative regulation of protein import into nucleusGO:004230820.049
cell type specific apoptotic processGO:0097285220.049
Human Mouse
positive regulation of nucleoside metabolic processGO:004597910.048
Worm
negative regulation of intracellular signal transductionGO:1902532220.048
Zebrafish
developmental growthGO:00485891660.047
response to glucocorticoidGO:005138410.047
multicellular organismal homeostasisGO:0048871290.046
regulation of response to cytokine stimulusGO:006075930.046
positive regulation of cell communicationGO:0010647560.046
Human Mouse
hemopoiesisGO:00300971830.045
negative regulation of mitotic cell cycleGO:0045930110.045
negative regulation of cytokine mediated signaling pathwayGO:000196020.045
calcium ion transportGO:0006816180.044
negative regulation of cellular metabolic processGO:0031324770.044
cellular response to lipopolysaccharideGO:007122230.044
modification of morphology or physiology of other organismGO:003582140.044
regulation of biosynthetic processGO:00098892500.043
regulation of catalytic activityGO:0050790550.043
regulation of molecular functionGO:0065009700.043
immune system processGO:00023762410.043
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.042
regulation of reactive oxygen species metabolic processGO:200037720.042
cellular response to endogenous stimulusGO:0071495680.042
urogenital system developmentGO:0001655970.042
cellular component disassemblyGO:002241110.042
regulation of oxidative stress induced cell deathGO:190320120.042
Human Mouse
cellular response to decreased oxygen levelsGO:003629410.042
cellular macromolecule biosynthetic processGO:00346452240.042
cellular component morphogenesisGO:00329893360.041
killing of cells of other organismGO:003164010.041
regulation of multicellular organismal developmentGO:20000262230.041
b cell activationGO:004211320.041
reactive oxygen species metabolic processGO:007259360.041
negative regulation of neuron projection regenerationGO:007057140.040
growthGO:00400071740.040
rna biosynthetic processGO:00327741810.039
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.039
cell cycle processGO:0022402530.039
positive regulation of cell cycleGO:004578730.038
carboxylic acid metabolic processGO:0019752220.038
positive regulation of multi organism processGO:004390230.038
cellular localizationGO:0051641970.038
larval developmentGO:000216420.038
negative regulation of macromolecule metabolic processGO:0010605760.037
embryonic skeletal system morphogenesisGO:0048704930.037
cell cycleGO:0007049930.036
cell killingGO:000190620.036
transcription from rna polymerase ii promoterGO:0006366800.036
positive regulation of hydrolase activityGO:0051345130.036
Zebrafish Worm
generation of neuronsGO:00486993850.036
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.036
reciprocal meiotic recombinationGO:000713110.036
positive regulation of peptidase activityGO:0010952100.036
Zebrafish
female gonad developmentGO:000858540.036
embryonic skeletal system developmentGO:0048706970.035
rna metabolic processGO:00160702190.035
negative regulation of cell cycleGO:0045786140.035
disruption of cells of other organismGO:004436410.035
negative regulation of apoptotic processGO:0043066550.035
cellular response to organic substanceGO:00713101050.035
negative regulation of catalytic activityGO:0043086210.034
response to radiationGO:0009314510.034
regulation of inflammatory responseGO:005072720.034
negative regulation of rna metabolic processGO:0051253480.034
camera type eye developmentGO:00430102220.034
carbohydrate derivative metabolic processGO:1901135610.034
Worm
amine metabolic processGO:000930820.033
regulation of purine nucleotide catabolic processGO:003312120.033
Worm
response to light stimulusGO:0009416460.033
response to other organismGO:0051707970.033
positive regulation of nucleotide catabolic processGO:003081310.033
Worm
regulation of mitotic cell cycleGO:0007346250.033
positive regulation of cellular protein metabolic processGO:0032270220.033
Zebrafish
guanosine containing compound metabolic processGO:190106840.033
Worm
cellular response to hormone stimulusGO:0032870390.033
cellular response to hypoxiaGO:007145610.033
system processGO:00030081850.032
phosphorus metabolic processGO:00067931090.032
Worm
ion transportGO:00068111140.032
regulation of interferon gamma mediated signaling pathwayGO:006033410.032
regulation of neuron apoptotic processGO:0043523170.032
Human Mouse
developmental growth involved in morphogenesisGO:0060560860.031
neuron apoptotic processGO:0051402200.031
Human Mouse
positive regulation of immune effector processGO:000269930.031
nucleobase containing compound metabolic processGO:00061392740.031
Worm
negative regulation of intracellular protein transportGO:009031730.031
regulation of nucleic acid templated transcriptionGO:19035062130.031
regulation of production of molecular mediator of immune responseGO:000270010.031
nitric oxide biosynthetic processGO:000680920.031
negative regulation of nitrogen compound metabolic processGO:0051172590.031
response to oxygen containing compoundGO:1901700550.030
negative regulation of molecular functionGO:0044092230.030
nucleic acid metabolic processGO:00903042440.030
leukocyte differentiationGO:0002521250.030
regulation of bindingGO:005109830.030
cellular component assemblyGO:00226071700.030
cellular response to oxygen levelsGO:007145310.030
cellular response to light stimulusGO:007148240.029
regulation of transcription dna templatedGO:00063552130.029
anatomical structure homeostasisGO:0060249360.029
cell cycle g2 m phase transitionGO:004483940.029
regulation of mitosisGO:000708890.029
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.029
regulation of cell proliferationGO:0042127370.029
regulation of i kappab kinase nf kappab signalingGO:004312240.028
regulation of response to biotic stimulusGO:000283120.028
dorsal ventral pattern formationGO:00099531250.028
tissue homeostasisGO:0001894250.028
cell proliferationGO:0008283800.028
cytokine mediated signaling pathwayGO:001922170.028
regulation of apoptotic signaling pathwayGO:2001233120.028
Human Zebrafish Mouse
multi organism processGO:00517041340.028
skeletal system developmentGO:00015011810.027
response to vitaminGO:003327330.027
positive regulation of signalingGO:0023056560.027
Human Mouse
intracellular signal transductionGO:0035556850.027
Human Zebrafish Mouse
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.027
Human Mouse
locomotor rhythmGO:004547530.027
regulation of cellular amino acid metabolic processGO:000652100.027
positive regulation of stress activated mapk cascadeGO:003287430.027
posterior lateral line neuromast hair cell developmentGO:003567730.027
i kappab kinase nf kappab signalingGO:000724940.027
negative regulation of cell deathGO:0060548600.027
production of molecular mediator of immune responseGO:000244020.026
tyrosine phosphorylation of stat proteinGO:000726010.026
odontogenesis of dentin containing toothGO:004247510.026
establishment of localization in cellGO:0051649770.026
regionalizationGO:00030022740.026
segmentationGO:0035282970.026
embryonic hemopoiesisGO:0035162530.026
nitric oxide metabolic processGO:004620920.026
fertilizationGO:000956630.026
phagocytosisGO:000690930.026
regulation of cell killingGO:003134120.026
cell morphogenesisGO:00009022890.025
amide biosynthetic processGO:004360410.025
negative regulation of kinase activityGO:003367340.025
negative regulation of protein kinase activityGO:000646940.025
single organism organelle organizationGO:19025891990.025
negative regulation of nucleobase containing compound metabolic processGO:0045934590.025
positive regulation of myeloid cell differentiationGO:004563920.025
cellular response to molecule of bacterial originGO:007121930.025
neurological system processGO:0050877620.025
defense response to fungusGO:005083220.025
membrane organizationGO:0061024210.025
Worm
multi organism cellular processGO:004476420.025
regenerationGO:0031099910.024
response to fatty acidGO:007054250.024
regulation of sterol transportGO:003237130.024
g1 s transition of mitotic cell cycleGO:000008210.024
response to lipidGO:0033993600.024
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.024
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.024
lipid storageGO:001991510.024
intrinsic apoptotic signaling pathwayGO:0097193200.024
Human Zebrafish Mouse
cellular response to starvationGO:000926710.024
blood vessel morphogenesisGO:00485142160.024
negative regulation of innate immune responseGO:004582420.023
positive regulation of biosynthetic processGO:0009891680.023
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.023
interferon gamma mediated signaling pathwayGO:006033310.023
response to corticosteroidGO:003196010.023
response to oxidative stressGO:0006979110.023
Human Mouse
macromolecule modificationGO:00434121110.023
cellular response to biotic stimulusGO:007121630.023
cell part morphogenesisGO:00329902460.023
response to amino acidGO:004320020.023
nuclear divisionGO:0000280230.023
regulation of dna templated transcription in response to stressGO:004362000.023
regulation of protein processingGO:0070613100.023
regulation of intracellular signal transductionGO:1902531570.023
Human Zebrafish Mouse
regulation of protein localization to plasma membraneGO:190307610.023
double strand break repairGO:000630230.023
regulation of reproductive processGO:200024140.023
embryonic cranial skeleton morphogenesisGO:0048701900.023
negative regulation of biosynthetic processGO:0009890550.023
regulation of calcium ion transportGO:005192420.023
meiotic cell cycle processGO:190304630.023
response to lipopolysaccharideGO:0032496130.022
negative regulation of map kinase activityGO:004340720.022
negative regulation of myeloid cell differentiationGO:004563810.022
response to cytokineGO:003409770.022
Human
cognitionGO:005089010.022
skeletal system morphogenesisGO:00487051020.022
regulation of cellular protein metabolic processGO:0032268520.022
negative regulation of protein metabolic processGO:0051248160.022
small molecule metabolic processGO:0044281770.022
Worm
nucleoside metabolic processGO:0009116110.022
Worm
positive regulation of signal transductionGO:0009967560.022
Human Mouse
viral processGO:001603210.022
regulation of establishment of protein localization to plasma membraneGO:009000310.022
toll like receptor signaling pathwayGO:000222440.021
negative regulation of nucleocytoplasmic transportGO:004682320.021
positive regulation of purine nucleotide metabolic processGO:190054490.021
Worm
response to oxygen radicalGO:000030520.021
regulation of cellular response to stressGO:0080135200.021
Human Mouse
organic cyclic compound biosynthetic processGO:19013622230.021
p38mapk cascadeGO:003806610.021
negative regulation of cellular component organizationGO:0051129160.021
response to nitrogen compoundGO:1901698190.021
regulation of proteolysisGO:0030162240.021
cellular response to nutrient levelsGO:003166920.021
response to uvGO:000941130.021
organelle assemblyGO:00709251100.021
antimicrobial humoral responseGO:001973020.021
response to ketoneGO:190165410.021
biosynthetic processGO:00090582940.021
digestive system developmentGO:00551232890.020
negative regulation of secretion by cellGO:190353120.020
nucleobase containing small molecule metabolic processGO:0055086320.020
Worm
protein localizationGO:0008104400.020
cellular component biogenesisGO:00440851780.020
regulation of nucleotide metabolic processGO:0006140170.020
Worm
regulation of protein complex assemblyGO:004325430.020
regulation of phosphate metabolic processGO:0019220430.019
Worm
organic acid metabolic processGO:0006082310.019
regulation of stem cell differentiationGO:200073640.019
nitrogen compound transportGO:0071705230.019
negative regulation of transcription dna templatedGO:0045892450.019
neuron projection regenerationGO:0031102160.019
response to axon injuryGO:0048678140.019
myeloid cell differentiationGO:0030099860.019
regulation of heart growthGO:006042020.019
negative regulation of intracellular transportGO:003238730.019
regulation of cellular ketone metabolic processGO:001056570.019
symbiosis encompassing mutualism through parasitismGO:004440340.019
innate immune responseGO:0045087130.019
response to hypoxiaGO:0001666250.019
cellular amine metabolic processGO:004410620.019
negative regulation of mapk cascadeGO:004340940.019
protein secretionGO:000930610.019
regulation of protein bindingGO:004339330.018
regulation of jak stat cascadeGO:004642530.018
meiotic nuclear divisionGO:000712640.018
cellular response to abiotic stimulusGO:007121440.018
negative regulation of cellular biosynthetic processGO:0031327550.018
cellular response to topologically incorrect proteinGO:003596720.018
sensory organ developmentGO:00074233930.018
regulation of localizationGO:00328791040.018
positive regulation of macromolecule biosynthetic processGO:0010557590.018
negative regulation of nucleic acid templated transcriptionGO:1903507450.018
establishment of protein localization to plasma membraneGO:009000210.018
somite developmentGO:0061053960.018
positive regulation of rna metabolic processGO:0051254590.018
oxoacid metabolic processGO:0043436310.018
negative regulation of axon regenerationGO:004868140.018
regulation of p38mapk cascadeGO:190074410.018
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.018
osteoclast differentiationGO:003031610.018
immune responseGO:0006955280.018
regulation of embryonic developmentGO:0045995470.017
response to hormoneGO:0009725480.017
muscle structure developmentGO:00610611960.017
cellular response to extracellular stimulusGO:003166820.017
positive regulation of dna metabolic processGO:005105410.017
cytoplasmic pattern recognition receptor signaling pathwayGO:000275310.017
regulation of lipid transportGO:003236840.017
positive regulation of catalytic activityGO:0043085250.017
Zebrafish Worm
positive regulation of multicellular organismal processGO:0051240520.017
stem cell proliferationGO:007208940.017
regulation of neuron deathGO:1901214180.017
Human Mouse
muscle cell developmentGO:00550011150.017
camera type eye morphogenesisGO:00485931080.017
b cell differentiationGO:003018310.017
mitotic cell cycle phase transitionGO:004477290.017
negative regulation of hormone secretionGO:004688820.016
organelle fissionGO:0048285230.016
peptidyl serine modificationGO:001820920.016
protein modification processGO:00362111000.016

mcl1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
musculoskeletal system diseaseDOID:1700.023
intestinal cancerDOID:1015500.023
cancerDOID:16200.023
colon carcinomaDOID:152000.023
colon cancerDOID:21900.023
gastrointestinal system cancerDOID:311900.023
large intestine cancerDOID:567200.023
disease of cellular proliferationDOID:1456600.023
colorectal cancerDOID:925600.023
organ system cancerDOID:005068600.023