Danio rerio

34 known processes

mif

macrophage migration inhibitory factor

mif biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of macromolecule metabolic processGO:00602553170.508
Mouse
neuron differentiationGO:00301823530.455
nucleobase containing compound biosynthetic processGO:00346542050.420
cellular biosynthetic processGO:00442492860.395
central nervous system developmentGO:00074173870.294
signal transductionGO:00071654550.289
Mouse
regulation of cellular biosynthetic processGO:00313262450.280
regulation of primary metabolic processGO:00800903110.269
Mouse
multicellular organism growthGO:003526440.236
regulation of cellular macromolecule biosynthetic processGO:20001122220.187
biosynthetic processGO:00090582940.185
aromatic compound biosynthetic processGO:00194382170.176
response to drugGO:004249330.174
regulation of gene expressionGO:00104682650.170
cellular nitrogen compound biosynthetic processGO:00442712180.161
brain developmentGO:00074202930.150
response to chemicalGO:00422213200.143
Mouse
cellular response to oxygen radicalGO:007145020.140
cellular macromolecule metabolic processGO:00442603910.138
Mouse
regulation of metabolic processGO:00192223590.138
Mouse
macromolecule biosynthetic processGO:00090592270.137
cellular aromatic compound metabolic processGO:00067252950.130
regulation of rna metabolic processGO:00512522240.128
hydrogen peroxide metabolic processGO:004274320.123
nucleic acid metabolic processGO:00903042440.117
organonitrogen compound metabolic processGO:1901564740.109
regulation of cellular metabolic processGO:00313233200.105
Mouse
regulation of biosynthetic processGO:00098892500.104
regulation of receptor activityGO:001046920.103
heterocycle biosynthetic processGO:00181302150.102
peptidyl serine phosphorylationGO:001810510.102
Mouse
agingGO:000756820.100
Mouse
heterocycle metabolic processGO:00464832900.100
organic cyclic compound biosynthetic processGO:19013622230.097
organic cyclic compound metabolic processGO:19013603010.097
erythrocyte differentiationGO:0030218540.096
regulation of biological qualityGO:00650082630.092
Mouse
regulation of macromolecule biosynthetic processGO:00105562250.091
peptidyl serine modificationGO:001820920.091
Mouse
head developmentGO:00603223030.089
cell death in response to oxidative stressGO:003647320.088
nitrogen compound metabolic processGO:00068073190.088
regulation of transcription dna templatedGO:00063552130.085
neuron developmentGO:00486662620.085
response to oxygen radicalGO:000030520.085
oxoacid metabolic processGO:0043436310.084
regulation of cellular amine metabolic processGO:003323800.084
amine metabolic processGO:000930820.083
regulation of multicellular organism growthGO:004001440.082
embryonic organ developmentGO:00485683810.080
regulation of nucleobase containing compound metabolic processGO:00192192500.080
regulation of cell communicationGO:00106462320.074
Mouse
regulation of cellular response to oxidative stressGO:190040720.073
regulation of transmembrane transporter activityGO:002289820.072
cell projection organizationGO:00300302840.071
regulation of nucleic acid templated transcriptionGO:19035062130.071
adult behaviorGO:003053420.071
cellular amino acid metabolic processGO:000652070.070
gene expressionGO:00104672520.070
cellular amine metabolic processGO:004410620.069
transcription dna templatedGO:00063511810.068
nucleoside monophosphate catabolic processGO:000912540.067
homeostasis of number of cellsGO:0048872620.064
Mouse
sensory organ morphogenesisGO:00905962000.062
hematopoietic or lymphoid organ developmentGO:00485341910.062
generation of neuronsGO:00486993850.060
response to stressGO:00069502630.060
Mouse
regulation of protein modification by small protein conjugation or removalGO:190332030.059
membrane hyperpolarizationGO:006008110.059
cellular catabolic processGO:0044248270.059
extrinsic apoptotic signaling pathwayGO:009719130.058
small molecule metabolic processGO:0044281770.058
cell deathGO:00082191210.057
positive regulation of biological processGO:00485182530.057
Mouse
organic substance biosynthetic processGO:19015762890.055
blood circulationGO:0008015870.054
response to superoxideGO:000030320.054
cellular nitrogen compound metabolic processGO:00346412900.053
cellular response to superoxideGO:007145120.053
negative regulation of nucleobase containing compound metabolic processGO:0045934590.052
carboxylic acid metabolic processGO:0019752220.052
response to oxygen containing compoundGO:1901700550.051
Mouse
intracellular signal transductionGO:0035556850.051
Mouse
regulation of phosphorylationGO:0042325260.051
Mouse
response to bacteriumGO:0009617580.051
Mouse
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.050
rna biosynthetic processGO:00327741810.049
cellular response to chemical stimulusGO:00708871570.049
Mouse
negative regulation of biological processGO:00485193040.049
nucleic acid templated transcriptionGO:00976591810.049
negative regulation of cellular metabolic processGO:0031324770.048
Mouse
hemopoiesisGO:00300971830.046
programmed cell deathGO:00125011190.046
monovalent inorganic cation transportGO:0015672420.046
organelle organizationGO:00069962270.046
apoptotic processGO:00069151160.046
negative regulation of signalingGO:0023057960.045
Mouse
myeloid cell homeostasisGO:0002262560.045
positive regulation of map kinase activityGO:004340630.044
Mouse
cell morphogenesisGO:00009022890.044
single organism localizationGO:19025782250.044
Mouse
transmembrane transportGO:00550851200.044
removal of superoxide radicalsGO:001943020.043
negative regulation of response to stimulusGO:00485851040.043
Mouse
cation transportGO:0006812810.043
cellular modified amino acid metabolic processGO:000657530.042
ribonucleoside monophosphate catabolic processGO:000915840.042
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.042
purine nucleoside monophosphate catabolic processGO:000912840.041
cell migrationGO:00164772370.040
regulation of multicellular organismal processGO:00512392770.040
Mouse
positive regulation of signal transductionGO:0009967560.040
Mouse
cellular amide metabolic processGO:004360340.039
positive regulation of programmed cell deathGO:0043068290.039
cellular response to reactive oxygen speciesGO:003461420.038
cell fate commitmentGO:0045165990.038
positive regulation of cell cycleGO:004578730.038
nucleobase containing compound metabolic processGO:00061392740.037
regulation of cytokine productionGO:000181730.037
Mouse
positive regulation of biosynthetic processGO:0009891680.037
single organism metabolic processGO:00447102170.036
Mouse
positive regulation of cytokine productionGO:000181920.036
Mouse
negative regulation of cellular biosynthetic processGO:0031327550.036
nuclear transportGO:005116940.036
positive regulation of cell deathGO:0010942290.036
photoreceptor cell differentiationGO:0046530550.036
deathGO:00162651210.035
purine ribonucleoside monophosphate catabolic processGO:000916940.035
rna metabolic processGO:00160702190.035
homeostatic processGO:00425921420.034
Mouse
regulation of ventricular cardiac muscle cell membrane repolarizationGO:006030710.034
regulation of oxidative stress induced cell deathGO:190320120.034
developmental growthGO:00485891660.034
negative regulation of intracellular protein transportGO:009031730.034
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.034
atp catabolic processGO:000620040.033
ribonucleotide metabolic processGO:0009259270.033
regulation of signal transductionGO:00099662250.033
Mouse
larval developmentGO:000216420.033
inorganic cation transmembrane transportGO:0098662500.032
cellular response to drugGO:003569010.032
stem cell developmentGO:0048864820.032
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.031
retina development in camera type eyeGO:00600411460.031
regulation of response to extracellular stimulusGO:003210410.031
regulation of transporter activityGO:003240920.030
action potentialGO:0001508190.030
regulation of rna biosynthetic processGO:20011412130.030
protein importGO:001703830.030
positive regulation of cellular amine metabolic processGO:003324000.030
modification dependent macromolecule catabolic processGO:004363230.030
response to organic substanceGO:00100331530.029
Mouse
regulation of cellular ketone metabolic processGO:001056570.029
developmental process involved in reproductionGO:0003006270.029
cellular response to lipopolysaccharideGO:007122230.029
Mouse
cellular component morphogenesisGO:00329893360.029
regulation of nuclease activityGO:003206910.029
cellular response to oxygen containing compoundGO:1901701200.029
Mouse
maintenance of locationGO:005123540.029
negative regulation of nitrogen compound metabolic processGO:0051172590.028
meiotic cell cycle processGO:190304630.028
phosphorylationGO:0016310690.028
Mouse
guanosine containing compound metabolic processGO:190106840.028
negative regulation of protein phosphorylationGO:000193340.027
negative regulation of kinase activityGO:003367340.027
negative regulation of macromolecule metabolic processGO:0010605760.026
Mouse
cellular protein metabolic processGO:00442671290.026
Mouse
phosphorus metabolic processGO:00067931090.026
Mouse
nucleoside phosphate metabolic processGO:0006753280.026
heart contractionGO:0060047710.026
regulation of protein ubiquitinationGO:003139630.026
signal transduction by p53 class mediatorGO:0072331130.026
Mouse
regulation of cell deathGO:00109411030.026
regulation of translational initiationGO:000644610.025
sensory organ developmentGO:00074233930.025
growthGO:00400071740.025
positive regulation of transportGO:005105020.025
Mouse
organic acid metabolic processGO:0006082310.025
purine containing compound metabolic processGO:0072521290.024
leukocyte proliferationGO:007066110.024
stem cell differentiationGO:00488631170.024
synaptic transmission cholinergicGO:000727140.024
cellular macromolecule biosynthetic processGO:00346452240.024
transcription from rna polymerase ii promoterGO:0006366800.023
positive regulation of cellular processGO:00485222010.023
Mouse
regulation of cellular amino acid metabolic processGO:000652100.023
nucleobase containing small molecule metabolic processGO:0055086320.023
heterocycle catabolic processGO:0046700150.023
mesenchyme developmentGO:00604851270.023
nuclear envelope organizationGO:000699820.023
regulation of protein bindingGO:004339330.023
positive regulation of response to stimulusGO:0048584800.023
Mouse
positive regulation of apoptotic signaling pathwayGO:200123510.023
negative regulation of cell communicationGO:0010648960.022
Mouse
regulation of programmed cell deathGO:00430671010.022
regulation of signalingGO:00230512350.022
Mouse
regulation of protein metabolic processGO:0051246560.022
Mouse
protein sumoylationGO:001692520.022
cellular localizationGO:0051641970.022
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.022
regulation of phosphate metabolic processGO:0019220430.022
Mouse
phosphate containing compound metabolic processGO:00067961080.022
Mouse
single organism nuclear importGO:190259330.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
superoxide metabolic processGO:000680120.022
cellular ketone metabolic processGO:0042180110.022
protein secretionGO:000930610.022
neurotransmitter transportGO:000683620.022
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233290.022
blood vessel developmentGO:00015682460.022
regulation of dna replicationGO:000627530.021
positive regulation of metabolic processGO:00098931080.021
Mouse
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.021
negative regulation of protein transportGO:005122430.021
cellular response to organic substanceGO:00713101050.021
Mouse
regulation of heart growthGO:006042020.021
carbohydrate derivative metabolic processGO:1901135610.021
regulation of organelle assemblyGO:190211540.021
purine nucleotide metabolic processGO:0006163270.021
positive regulation of multicellular organismal processGO:0051240520.021
Mouse
positive regulation of muscle organ developmentGO:004863610.021
circulatory system processGO:0003013870.021
regulation of response to oxidative stressGO:190288220.021
negative regulation of catabolic processGO:000989530.021
regulation of response to stimulusGO:00485832690.021
Mouse
nucleotide metabolic processGO:0009117280.021
regulation of intracellular signal transductionGO:1902531570.020
Mouse
cellular nitrogen compound catabolic processGO:0044270150.020
neuron neuron synaptic transmissionGO:000727010.020
peripheral nervous system developmentGO:0007422550.020
single organism biosynthetic processGO:0044711710.020
positive regulation of intracellular signal transductionGO:1902533150.020
Mouse
stem cell proliferationGO:007208940.020
negative regulation of programmed cell deathGO:0043069580.020
tube morphogenesisGO:00352393490.020
cell morphogenesis involved in differentiationGO:00009041950.020
regulation of meiotic cell cycleGO:005144510.019
protein complex localizationGO:003150310.019
dna catabolic processGO:000630810.019
regulation of epithelial cell proliferationGO:005067830.019
regulation of insulin like growth factor receptor signaling pathwayGO:004356710.019
mesenchymal cell differentiationGO:0048762870.019
erythrocyte homeostasisGO:0034101550.019
positive regulation of apoptotic processGO:0043065290.019
regulation of nitrogen compound metabolic processGO:00511712510.018
lipid metabolic processGO:0006629520.018
positive regulation of striated muscle cell differentiationGO:005115510.018
negative regulation of macromolecule biosynthetic processGO:0010558480.018
nucleocytoplasmic transportGO:000691340.018
eye developmentGO:00016542770.018
signal transduction by phosphorylationGO:0023014180.018
Mouse
regulation of dna catabolic processGO:190362410.018
negative regulation of metabolic processGO:0009892860.018
Mouse
insulin like growth factor receptor signaling pathwayGO:004800940.018
positive regulation of wound healingGO:009030310.018
protein import into nucleusGO:000660630.018
camera type eye developmentGO:00430102220.017
adherens junction organizationGO:003433240.017
aromatic compound catabolic processGO:0019439150.017
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.017
negative regulation of biosynthetic processGO:0009890550.017
intracellular transportGO:0046907320.017
lipid storageGO:001991510.017
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.017
response to lipidGO:0033993600.017
Mouse
positive regulation of striated muscle tissue developmentGO:004584410.017
cellular protein modification processGO:00064641000.017
Mouse
ion transmembrane transportGO:0034220910.017
oocyte maturationGO:000155640.017
retina morphogenesis in camera type eyeGO:0060042790.017
exocrine pancreas developmentGO:0031017280.017
stem cell maintenanceGO:001982740.016
ribosomal small subunit biogenesisGO:004227420.016
positive regulation of signalingGO:0023056560.016
Mouse
negative regulation of signal transductionGO:0009968940.016
Mouse
positive regulation of muscle tissue developmentGO:190186310.016
cellular response to stressGO:0033554620.016
Mouse
pancreas developmentGO:0031016840.016
negative regulation of protein kinase activityGO:000646940.016
regulation of establishment of protein localizationGO:007020140.016
specification of symmetryGO:00097992040.016
negative regulation of rna metabolic processGO:0051253480.016
cell agingGO:000756920.016
Mouse
cell projection morphogenesisGO:00488582440.015
regulation of metal ion transportGO:001095940.015
reproductionGO:0000003400.015
cellular macromolecular complex assemblyGO:0034622240.015
nucleobase containing compound catabolic processGO:0034655150.015
heart morphogenesisGO:00030071560.015
cell morphogenesis involved in neuron differentiationGO:00486671630.015
cell substrate junction assemblyGO:000704420.015
reactive oxygen species metabolic processGO:007259360.015
positive regulation of epithelial cell differentiationGO:003085820.015
negative regulation of dna metabolic processGO:005105340.015
regulation of wound healingGO:006104120.015
cellular component movementGO:00069283350.015
cell proliferation in forebrainGO:002184630.015
sensory system developmentGO:0048880760.015
protein targeting to nucleusGO:004474430.015
regulation of cardiac muscle tissue developmentGO:005502410.015
response to other organismGO:0051707970.015
Mouse
negative regulation of cellular catabolic processGO:003133030.015
cell part morphogenesisGO:00329902460.015
urogenital system developmentGO:0001655970.014
regulation of erythrocyte differentiationGO:004564620.014
negative regulation of cell deathGO:0060548600.014
regulation of ion transmembrane transporter activityGO:003241220.014
regulation of kinase activityGO:0043549150.014
Mouse
neurotransmitter secretionGO:000726920.014
autophagyGO:000691440.014
positive regulation of myeloid cell differentiationGO:004563920.014
inner ear developmentGO:00488391260.014
positive regulation of nuclease activityGO:003207510.014
neuron fate determinationGO:004866420.014
negative regulation of cytoplasmic transportGO:190365020.014
negative regulation of leukocyte differentiationGO:190210610.014
regulation of cellular protein metabolic processGO:0032268520.014
Mouse
immune system processGO:00023762410.013
Mouse
regulation of reactive oxygen species metabolic processGO:200037720.013
negative regulation of intracellular transportGO:003238730.013
glucose homeostasisGO:004259310.013
regulation of protein modification processGO:0031399290.013
Mouse
response to uvGO:000941130.013
protein phosphorylationGO:0006468470.013
Mouse
establishment of protein localization to organelleGO:007259440.013
guanosine containing compound catabolic processGO:190106920.013
negative regulation of transcription dna templatedGO:0045892450.013
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.013
regulation of developmental processGO:00507932470.013
morphogenesis of an epitheliumGO:00020093330.013
cation transmembrane transportGO:0098655650.013
liver developmentGO:0001889960.013
mitochondrion organizationGO:000700540.013
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.013
sodium ion transmembrane transportGO:0035725210.013
metal ion transportGO:0030001580.012
phagocytosisGO:000690930.012
cellular response to molecule of bacterial originGO:007121930.012
Mouse
protein modification processGO:00362111000.012
Mouse
mesenchymal cell developmentGO:0014031780.012
g1 s transition of mitotic cell cycleGO:000008210.012
entrainment of circadian clockGO:000964920.012
negative regulation of apoptotic processGO:0043066550.012
macromolecule modificationGO:00434121110.012
Mouse
cellular amino acid biosynthetic processGO:000865220.012
hormone transportGO:000991420.012
cell proliferationGO:0008283800.012
protein stabilizationGO:005082120.012
embryonic limb morphogenesisGO:003032620.012
regulation of carbohydrate metabolic processGO:000610940.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
regulation of reproductive processGO:200024140.012
organic substance transportGO:0071702580.012
Mouse
regulation of autophagyGO:001050630.012
monoamine transportGO:001584410.012
inorganic ion transmembrane transportGO:0098660570.012
regulation of nucleocytoplasmic transportGO:004682220.012
protein acylationGO:004354330.011
ribose phosphate metabolic processGO:0019693270.011
digestive tract developmentGO:00485652650.011
determination of bilateral symmetryGO:00098552040.011
ovarian follicle developmentGO:000154120.011
regulation of postsynaptic membrane potentialGO:006007810.011
eye morphogenesisGO:00485921440.011
small molecule catabolic processGO:004428230.011
negative regulation of epithelial cell proliferationGO:005068010.011
regulation of transmembrane transportGO:0034762180.011
purine ribonucleotide metabolic processGO:0009150270.011
negative regulation of cellular processGO:00485232830.011
response to hydrogen peroxideGO:004254230.011
gtp metabolic processGO:004603940.011
endocardium formationGO:006021410.011
regulation of cytoplasmic transportGO:190364940.011
angiogenesisGO:00015251580.011
negative regulation of oxidative stress induced cell deathGO:190320220.011
regulation of cell activationGO:005086510.011
single organism transportGO:00447652060.011
Mouse
regulation of bindingGO:005109830.011
hydrogen transportGO:000681870.011
mononuclear cell proliferationGO:003294310.011
otolith developmentGO:0048840320.011
membrane repolarizationGO:008600920.011
regulation of photoreceptor cell differentiationGO:004653220.011
nucleoside biosynthetic processGO:000916320.011
organophosphate metabolic processGO:0019637370.011
regulation of neurotransmitter transportGO:005158810.010
heart developmentGO:00075073130.010
embryonic organ morphogenesisGO:00485622740.010
chromosome organization involved in meiosisGO:007019210.010
intrinsic apoptotic signaling pathwayGO:0097193200.010
heart processGO:0003015710.010
organic cyclic compound catabolic processGO:1901361150.010
endocardium morphogenesisGO:000316040.010
lipid homeostasisGO:005508830.010
regulation of alcohol biosynthetic processGO:190293010.010
regulation of protein phosphorylationGO:0001932180.010
Mouse
camera type eye morphogenesisGO:00485931080.010
microtubule based movementGO:0007018330.010
carbon dioxide transportGO:001567030.010

mif disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.022
disease of metabolismDOID:001466700.016
inherited metabolic disorderDOID:65500.016
lysosomal storage diseaseDOID:321100.011