Danio rerio

25 known processes

msh6

mutS homolog 6 (E. coli)

(Aliases: wu:fb36c12,cb326)

msh6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular aromatic compound metabolic processGO:00067252950.968
nitrogen compound metabolic processGO:00068073190.903
meiosis iGO:000712710.783
Fly
nucleobase containing compound metabolic processGO:00061392740.731
locomotionGO:00400113130.708
meiotic nuclear divisionGO:000712640.706
Fly
cellular nitrogen compound metabolic processGO:00346412900.696
regulation of macromolecule metabolic processGO:00602553170.684
Human Mouse
cellular macromolecule metabolic processGO:00442603910.654
organic substance biosynthetic processGO:19015762890.624
signal transductionGO:00071654550.620
Mouse
immune system developmentGO:00025201910.576
Mouse
regulation of biosynthetic processGO:00098892500.573
organic cyclic compound metabolic processGO:19013603010.549
organelle organizationGO:00069962270.541
regulation of metabolic processGO:00192223590.540
Human Mouse
heterocycle biosynthetic processGO:00181302150.531
larval developmentGO:000216420.520
response to stressGO:00069502630.453
Human Mouse Fly
establishment of localizationGO:00512342440.418
negative regulation of cellular processGO:00485232830.412
Human Mouse
purine nucleoside monophosphate catabolic processGO:000912840.400
Human
nucleic acid metabolic processGO:00903042440.371
cellular biosynthetic processGO:00442492860.359
single organism organelle organizationGO:19025891990.338
aromatic compound biosynthetic processGO:00194382170.337
heterocycle metabolic processGO:00464832900.319
rna metabolic processGO:00160702190.307
transportGO:00068102200.305
negative regulation of histone modificationGO:003105710.304
nuclear divisionGO:0000280230.303
Fly
meiotic cell cycle processGO:190304630.287
Fly
mitotic cell cycle processGO:1903047480.286
neuron differentiationGO:00301823530.263
biosynthetic processGO:00090582940.257
cellular nitrogen compound biosynthetic processGO:00442712180.242
localization of cellGO:00516742440.238
negative regulation of biological processGO:00485193040.232
Human Mouse
cellular macromolecule biosynthetic processGO:00346452240.230
negative regulation of cellular metabolic processGO:0031324770.216
Human Mouse
regulation of primary metabolic processGO:00800903110.204
Human Mouse
regulation of nitrogen compound metabolic processGO:00511712510.202
Human Mouse
single organism localizationGO:19025782250.197
immune system processGO:00023762410.193
Mouse
cell projection morphogenesisGO:00488582440.191
nucleobase containing compound biosynthetic processGO:00346542050.187
cellular component biogenesisGO:00440851780.182
muscle organ developmentGO:00075171010.176
regulation of gene expressionGO:00104682650.176
negative regulation of histone methylationGO:003106110.174
macromolecular complex assemblyGO:0065003350.173
regulation of cellular biosynthetic processGO:00313262450.172
single organism metabolic processGO:00447102170.170
regulation of cellular metabolic processGO:00313233200.168
Human Mouse
cell morphogenesisGO:00009022890.166
dna metabolic processGO:0006259270.164
negative regulation of metabolic processGO:0009892860.163
Human Mouse
regulation of macromolecule biosynthetic processGO:00105562250.161
deathGO:00162651210.156
Mouse
cell proliferationGO:0008283800.151
mitotic cell cycleGO:0000278640.142
nucleoside monophosphate catabolic processGO:000912540.142
Human
phosphorus metabolic processGO:00067931090.141
Human
positive regulation of cellular processGO:00485222010.130
cognitionGO:005089010.125
cellular component assemblyGO:00226071700.125
regulation of nucleobase containing compound metabolic processGO:00192192500.123
Human Mouse
somatic cell dna recombinationGO:001644410.122
Mouse
regulation of biological qualityGO:00650082630.121
cell projection organizationGO:00300302840.118
hematopoietic or lymphoid organ developmentGO:00485341910.114
cellular protein metabolic processGO:00442671290.114
microtubule based processGO:0007017600.112
protein complex assemblyGO:0006461300.110
meiotic chromosome segregationGO:004513230.109
chromosome organizationGO:0051276310.108
regulation of cell deathGO:00109411030.107
cell migrationGO:00164772370.107
cell cycle processGO:0022402530.105
Fly
purine ribonucleoside monophosphate catabolic processGO:000916940.105
Human
organelle fissionGO:0048285230.104
Fly
embryo development ending in birth or egg hatchingGO:00097922710.104
mitotic recombinationGO:000631220.102
mitotic dna integrity checkpointGO:004477440.101
immunoglobulin mediated immune responseGO:001606430.101
Mouse
proteolysis involved in cellular protein catabolic processGO:005160330.100
gene expressionGO:00104672520.100
regulation of multicellular organismal processGO:00512392770.099
macromolecule biosynthetic processGO:00090592270.094
positive regulation of biological processGO:00485182530.094
Human
mitotic dna damage checkpointGO:004477340.092
intracellular signal transductionGO:0035556850.092
Mouse
regulation of developmental processGO:00507932470.091
chromosome segregationGO:0007059120.090
regulation of cellular macromolecule biosynthetic processGO:20001122220.088
lymphocyte mediated immunityGO:000244950.086
Mouse
response to chemicalGO:00422213200.085
regulation of meiotic cell cycleGO:005144510.085
regulation of protein transportGO:005122330.083
cellular component movementGO:00069283350.082
camera type eye developmentGO:00430102220.082
zymogen activationGO:003163830.081
positive regulation of programmed cell deathGO:0043068290.081
cell cycleGO:0007049930.080
Fly
negative regulation of cell cycle phase transitionGO:190198850.080
cell part morphogenesisGO:00329902460.079
cellular component assembly involved in morphogenesisGO:00109271070.078
heart developmentGO:00075073130.076
modification dependent macromolecule catabolic processGO:004363230.074
neuron projection developmentGO:00311751800.073
regulation of nucleic acid templated transcriptionGO:19035062130.072
cell deathGO:00082191210.070
Mouse
multicellular organism growthGO:003526440.068
immunoglobulin productionGO:000237710.064
Mouse
neuron developmentGO:00486662620.064
single organism biosynthetic processGO:0044711710.063
phosphate containing compound metabolic processGO:00067961080.062
Human
regulation of cysteine type endopeptidase activityGO:2000116210.062
chromosome organization involved in meiosisGO:007019210.062
cell morphogenesis involved in differentiationGO:00009041950.059
sister chromatid cohesionGO:000706220.059
cytoskeleton organizationGO:0007010960.059
regulation of peptidase activityGO:0052547230.057
protein complex subunit organizationGO:0071822460.056
tube morphogenesisGO:00352393490.056
multi organism processGO:00517041340.056
single organism transportGO:00447652060.056
negative regulation of cell deathGO:0060548600.056
regulation of rna metabolic processGO:00512522240.055
regulation of histone h3 k9 methylationGO:005157020.054
regulation of response to stimulusGO:00485832690.054
protein complex biogenesisGO:0070271300.054
dna methylation on cytosineGO:003277630.053
cellular protein catabolic processGO:004425740.053
regulation of molecular functionGO:0065009700.053
Human
transcription dna templatedGO:00063511810.053
regionalizationGO:00030022740.052
regulation of striated muscle contractionGO:000694220.052
macromolecule localizationGO:0033036540.052
muscle structure developmentGO:00610611960.052
negative regulation of macromolecule metabolic processGO:0010605760.052
Human Mouse
cell surface receptor signaling pathwayGO:00071663250.052
organic substance catabolic processGO:1901575280.051
Human
nucleic acid templated transcriptionGO:00976591810.051
purine ribonucleotide metabolic processGO:0009150270.048
Human
growthGO:00400071740.048
lipid storageGO:001991510.047
regulation of programmed cell deathGO:00430671010.047
protein metabolic processGO:00195381830.047
sex determinationGO:000753010.047
negative regulation of nitrogen compound metabolic processGO:0051172590.046
Human Mouse
maintenance of locationGO:005123540.046
regulation of protein metabolic processGO:0051246560.045
spindle assemblyGO:005122520.045
positive regulation of cell cycleGO:004578730.043
cellular component morphogenesisGO:00329893360.043
cell motilityGO:00488702440.042
regulation of catalytic activityGO:0050790550.042
Human
response to organic substanceGO:00100331530.042
modification dependent protein catabolic processGO:001994130.042
macromolecular complex subunit organizationGO:0043933740.042
regulation of cell cycle phase transitionGO:190198780.041
regulation of intracellular signal transductionGO:1902531570.041
regulation of rna biosynthetic processGO:20011412130.040
apoptotic processGO:00069151160.040
Mouse
chordate embryonic developmentGO:00430092710.040
negative regulation of transcription dna templatedGO:0045892450.040
regulation of multicellular organism growthGO:004001440.040
muscle cell developmentGO:00550011150.040
ubiquitin dependent protein catabolic processGO:000651130.039
cellular response to chemical stimulusGO:00708871570.039
cellular response to organic substanceGO:00713101050.039
immune effector processGO:0002252230.038
Mouse
organelle assemblyGO:00709251100.038
positive regulation of catabolic processGO:000989640.038
regulation of dendrite developmentGO:005077330.038
sensory organ developmentGO:00074233930.038
regulation of apoptotic processGO:0042981980.037
negative regulation of dna metabolic processGO:005105340.037
Human Mouse
hemopoiesisGO:00300971830.037
system processGO:00030081850.036
developmental growthGO:00485891660.036
response to amino acidGO:004320020.035
negative regulation of biosynthetic processGO:0009890550.035
regulation of cell cycleGO:0051726520.035
purine containing compound metabolic processGO:0072521290.035
Human
positive regulation of cellular metabolic processGO:0031325940.034
positive regulation of cytokine productionGO:000181920.034
rna biosynthetic processGO:00327741810.034
stem cell maintenanceGO:001982740.033
positive regulation of cell deathGO:0010942290.033
specification of symmetryGO:00097992040.033
positive regulation of nitrogen compound metabolic processGO:0051173690.032
small molecule metabolic processGO:0044281770.032
Human
double strand break repairGO:000630230.031
single organism reproductive processGO:0044702400.031
positive regulation of chromatin modificationGO:190331010.031
mitotic cell cycle phase transitionGO:004477290.030
organonitrogen compound metabolic processGO:1901564740.030
Human
cellular localizationGO:0051641970.030
atp catabolic processGO:000620040.030
Human
intracellular receptor signaling pathwayGO:0030522300.030
cell cell recognitionGO:000998810.030
synaptic growth at neuromuscular junctionGO:005112420.030
positive regulation of hydrolase activityGO:0051345130.029
Human
g1 s transition of mitotic cell cycleGO:000008210.029
protein localizationGO:0008104400.029
generation of neuronsGO:00486993850.029
regulation of signal transductionGO:00099662250.029
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.029
reproductionGO:0000003400.029
Fly
response to uvGO:000941130.029
Mouse
response to external stimulusGO:00096052640.029
skeletal muscle organ developmentGO:0060538780.029
carbohydrate derivative metabolic processGO:1901135610.028
Human
programmed cell deathGO:00125011190.028
Mouse
protein importGO:001703830.028
determination of bilateral symmetryGO:00098552040.027
organic cyclic compound biosynthetic processGO:19013622230.027
rna localizationGO:000640340.027
ribonucleoside monophosphate catabolic processGO:000915840.027
Human
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233290.027
regulation of establishment of protein localizationGO:007020140.026
establishment of protein localization to organelleGO:007259440.026
positive regulation of gene expressionGO:0010628710.026
negative regulation of nucleobase containing compound metabolic processGO:0045934590.025
Human Mouse
negative regulation of signal transductionGO:0009968940.025
cell migration involved in gastrulationGO:0042074790.025
regulation of localizationGO:00328791040.025
thymus developmentGO:0048538100.025
positive regulation of transportGO:005105020.025
establishment of localization in cellGO:0051649770.025
regulation of protein localization to nucleusGO:190018020.025
b cell differentiationGO:003018310.025
nucleoside phosphate metabolic processGO:0006753280.024
Human
actin mediated cell contractionGO:007025210.024
positive regulation of mrna metabolic processGO:190331320.024
homeostasis of number of cellsGO:0048872620.024
fertilizationGO:000956630.024
homeostatic processGO:00425921420.024
negative regulation of programmed cell deathGO:0043069580.024
organophosphate metabolic processGO:0019637370.024
Human
positive regulation of muscle organ developmentGO:004863610.024
striated muscle tissue developmentGO:00147061100.023
gtp metabolic processGO:004603940.023
morphogenesis of an epitheliumGO:00020093330.023
positive regulation of macromolecule metabolic processGO:0010604930.023
cellular response to dna damage stimulusGO:0006974240.023
Human Mouse Fly
cellular response to stressGO:0033554620.023
Human Mouse Fly
cell morphogenesis involved in neuron differentiationGO:00486671630.023
negative regulation of chromosome organizationGO:200125110.023
male meiosisGO:000714020.022
regulation of purine nucleotide catabolic processGO:003312120.022
regulation of translational initiationGO:000644610.022
cell substrate adhesionGO:003158940.022
reproductive processGO:0022414400.022
multi organism reproductive processGO:0044703360.022
cell fate commitmentGO:0045165990.021
cellular catabolic processGO:0044248270.021
Human
regulation of dna recombinationGO:000001820.021
Human Mouse
negative regulation of apoptotic processGO:0043066550.021
mrna metabolic processGO:0016071200.021
microtubule polymerizationGO:004678520.021
regulation of developmental growthGO:0048638380.021
muscle cell differentiationGO:00426921390.021
positive regulation of cellular catabolic processGO:003133130.021
camera type eye photoreceptor cell differentiationGO:0060219190.021
response to abiotic stimulusGO:00096281220.020
Mouse
intra s dna damage checkpointGO:003157310.020
neuron projection morphogenesisGO:00488121610.020
dna biosynthetic processGO:007189730.020
reciprocal dna recombinationGO:003582510.020
negative regulation of gene expressionGO:0010629650.020
heart contractionGO:0060047710.020
reciprocal meiotic recombinationGO:000713110.020
guanosine containing compound metabolic processGO:190106840.020
regulation of histone methylationGO:003106030.020
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.019
taxisGO:00423301090.019
retina development in camera type eyeGO:00600411460.019
transmembrane transportGO:00550851200.019
pyrimidine containing compound biosynthetic processGO:007252820.019
regulation of neuron projection developmentGO:0010975400.019
eye developmentGO:00016542770.019
proteasomal protein catabolic processGO:001049820.019
sensory organ morphogenesisGO:00905962000.019
regulation of transcription dna templatedGO:00063552130.019
positive regulation of metabolic processGO:00098931080.019
Human
microtubule organizing center organizationGO:003102310.019
agingGO:000756820.019
Mouse
pyrimidine containing compound metabolic processGO:007252730.019
microtubule cytoskeleton organization involved in mitosisGO:190285010.019
embryonic heart tube morphogenesisGO:00031431080.018
regulation of mitotic cell cycle phase transitionGO:190199080.018
female meiotic divisionGO:000714320.018
regulation of cell developmentGO:00602841000.018
rna transportGO:005065820.018
regulation of cell communicationGO:00106462320.018
establishment of rna localizationGO:005123630.018
regulation of cellular component organizationGO:0051128860.018
positive regulation of apoptotic processGO:0043065290.018
protein stabilizationGO:005082120.018
protein heterooligomerizationGO:005129110.018
cellular protein localizationGO:0034613200.018
phagocytosisGO:000690930.018
specification of axis polarityGO:006500140.017
b cell mediated immunityGO:001972430.017
Mouse
response to woundingGO:00096111160.017
negative regulation of cellular biosynthetic processGO:0031327550.017
negative regulation of dna recombinationGO:004591020.017
Human Mouse
mitotic nuclear divisionGO:0007067180.017
definitive hemopoiesisGO:0060216180.017
erythrocyte differentiationGO:0030218540.017
macromolecule catabolic processGO:0009057150.017
regulation of cell differentiationGO:00455951420.017
cell cycle g1 s phase transitionGO:004484310.017
response to radiationGO:0009314510.017
Mouse
guanosine containing compound catabolic processGO:190106920.016
protein maturationGO:0051604120.016
spindle assembly involved in meiosisGO:009030610.016
dendrite developmentGO:001635890.016
epithelial cell morphogenesisGO:000338220.016
retina morphogenesis in camera type eyeGO:0060042790.016
embryonic skeletal joint developmentGO:007249830.016
dna catabolic processGO:000630810.016
cell chemotaxisGO:0060326170.016
nuclear transportGO:005116940.016
g2 m transition of mitotic cell cycleGO:000008640.016
ribonucleotide metabolic processGO:0009259270.016
Human
circulatory system processGO:0003013870.015
ribose phosphate metabolic processGO:0019693270.015
Human
protein processingGO:0016485120.015
multicellular organism reproductionGO:0032504350.015
oocyte maturationGO:000155640.015
negative regulation of catabolic processGO:000989530.015
positive regulation of signal transductionGO:0009967560.015
positive regulation of cell communicationGO:0010647560.015
regulation of endopeptidase activityGO:0052548230.015
meiotic cell cycleGO:005132150.015
Fly
gtp catabolic processGO:000618420.015
cellular macromolecule catabolic processGO:0044265120.015
actin filament based processGO:0030029640.015
germ cell developmentGO:0007281220.015
mrna stabilizationGO:004825540.015
double strand break repair via nonhomologous end joiningGO:000630310.014
microtubule cytoskeleton organizationGO:0000226330.014
oxoacid metabolic processGO:0043436310.014
adult behaviorGO:003053420.014
regulation of dna replicationGO:000627530.014
sex differentiationGO:000754850.014
digestive tract developmentGO:00485652650.014
developmental programmed cell deathGO:001062340.014
actin filament based movementGO:003004810.014
response to light stimulusGO:0009416460.014
Mouse
b cell activationGO:004211320.014
Mouse
negative regulation of dna replicationGO:000815620.014
regulation of synapse organizationGO:005080730.014
rna export from nucleusGO:000640510.014
regulation of proteolysisGO:0030162240.014
negative regulation of chromatin modificationGO:190330910.014
endocytosisGO:0006897160.014
regulation of ras gtpase activityGO:003231820.013
axon developmentGO:00615641660.013
regulation of protein targetingGO:190353320.013
regulation of nucleoside metabolic processGO:000911820.013
neuron projection extensionGO:1990138450.013
signal transduction by p53 class mediatorGO:0072331130.013
central nervous system developmentGO:00074173870.013
neurological system processGO:0050877620.013
gland developmentGO:00487321430.013
germ line stem cell divisionGO:004207810.013
regulation of nucleotide catabolic processGO:003081120.013
regulation of protein catabolic processGO:004217610.013
regulation of cytokine productionGO:000181730.013
polarized epithelial cell differentiationGO:003085940.013
nucleobase containing small molecule metabolic processGO:0055086320.013
Human
peptidyl serine phosphorylationGO:001810510.013
organonitrogen compound biosynthetic processGO:1901566470.013
positive regulation of response to stimulusGO:0048584800.013
synaptic transmission cholinergicGO:000727140.013
negative regulation of proteolysisGO:0045861100.013
regulation of gtp catabolic processGO:003312420.013
regulation of gtpase activityGO:004308720.012
mitotic cell cycle checkpointGO:000709350.012
protein polymerizationGO:005125840.012
regulation of muscle contractionGO:000693730.012
nuclear importGO:005117030.012
apoptotic signaling pathwayGO:0097190230.012
Mouse
cellular carbohydrate metabolic processGO:004426240.012
cellular response to reactive oxygen speciesGO:003461420.012
positive regulation of cell proliferationGO:0008284150.012
nucleobase containing compound transportGO:001593120.012
negative regulation of defense responseGO:003134820.012
mitotic g2 dna damage checkpointGO:000709530.012
axonogenesisGO:00074091520.012
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.012
regulation of cellular ketone metabolic processGO:001056570.012
somitogenesisGO:0001756870.012
sexual reproductionGO:0019953360.012
ion transportGO:00068111140.012
positive regulation of cellular biosynthetic processGO:0031328680.012
meiotic spindle organizationGO:000021210.012
regulation of cardiac muscle contractionGO:005511720.012
regulation of protein complex assemblyGO:004325430.012
g2 dna damage checkpointGO:003157230.012
regulation of signalingGO:00230512350.012
cardiac atrium developmentGO:000323040.012
embryonic skeletal joint morphogenesisGO:006027230.011
histone h3 k9 modificationGO:006164750.011
stem cell proliferationGO:007208940.011
proteolysisGO:0006508380.011
stem cell differentiationGO:00488631170.011
regulation of membrane potentialGO:0042391230.011
negative regulation of kinase activityGO:003367340.011
negative regulation of mitotic cell cycle phase transitionGO:190199150.011
immune responseGO:0006955280.011
Mouse
behaviorGO:0007610740.011
negative regulation of translationGO:001714810.011
nucleotide metabolic processGO:0009117280.011
Human
organic acid metabolic processGO:0006082310.011
establishment of organelle localizationGO:0051656450.011
negative regulation of multi organism processGO:004390130.011
regulation of cellular protein metabolic processGO:0032268520.011
photoreceptor cell developmentGO:0042461400.011
determination of heart left right asymmetryGO:00613711170.011
cellular macromolecular complex assemblyGO:0034622240.011
macromolecule modificationGO:00434121110.011
positive regulation of gtp catabolic processGO:003312610.010
cilium organizationGO:0044782710.010
myeloid cell homeostasisGO:0002262560.010
posttranscriptional regulation of gene expressionGO:0010608140.010
intrinsic apoptotic signaling pathwayGO:0097193200.010
Mouse
digestive tract morphogenesisGO:00485462310.010
translational initiationGO:000641330.010
cellular protein modification processGO:00064641000.010
cellular response to oxygen levelsGO:007145310.010
spermatid differentiationGO:004851520.010
response to temperature stimulusGO:0009266150.010
regulation of mrna processingGO:005068430.010

msh6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.031
organ system cancerDOID:005068600.012
Human
disease of cellular proliferationDOID:1456600.012
Human
cancerDOID:16200.012
Human