Danio rerio

0 known processes

ogdh

oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

(Aliases: MGC73296,im:7045267,wu:fa06d01,zgc:73296,wu:fb98a04)

ogdh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.318
Worm
larval developmentGO:000216420.267
Worm
cellular respirationGO:004533330.144
vasculature developmentGO:00019442780.127
single organism localizationGO:19025782250.115
positive regulation of biological processGO:00485182530.113
oxoacid metabolic processGO:0043436310.109
multicellular organism growthGO:003526440.098
blood vessel developmentGO:00015682460.089
organic acid metabolic processGO:0006082310.086
specification of symmetryGO:00097992040.069
blood vessel morphogenesisGO:00485142160.068
regulation of multicellular organism growthGO:004001440.067
coenzyme biosynthetic processGO:000910820.067
determination of left right symmetryGO:00073681790.062
embryo development ending in birth or egg hatchingGO:00097922710.061
Worm
tube morphogenesisGO:00352393490.061
negative regulation of biological processGO:00485193040.059
carboxylic acid metabolic processGO:0019752220.059
small molecule metabolic processGO:0044281770.058
cellular amine metabolic processGO:004410620.058
rna metabolic processGO:00160702190.055
single organism metabolic processGO:00447102170.055
locomotionGO:00400113130.055
positive regulation of catabolic processGO:000989640.054
signal transductionGO:00071654550.053
pyruvate metabolic processGO:000609010.052
transmembrane transportGO:00550851200.051
regulation of gene expressionGO:00104682650.051
morphogenesis of an epitheliumGO:00020093330.050
cation transportGO:0006812810.049
mitochondrion organizationGO:000700540.048
cellular component movementGO:00069283350.048
growthGO:00400071740.048
carboxylic acid catabolic processGO:004639530.047
maintenance of locationGO:005123540.047
cellular macromolecule metabolic processGO:00442603910.044
positive regulation of transportGO:005105020.043
cell surface receptor signaling pathwayGO:00071663250.042
nucleobase containing compound metabolic processGO:00061392740.041
phagocytosisGO:000690930.041
regenerationGO:0031099910.040
response to external stimulusGO:00096052640.039
dicarboxylic acid metabolic processGO:004364810.039
organonitrogen compound metabolic processGO:1901564740.038
amine metabolic processGO:000930820.038
localization of cellGO:00516742440.038
establishment of localizationGO:00512342440.037
cell migrationGO:00164772370.037
oxidation reduction processGO:0055114410.036
regulation of macromolecule metabolic processGO:00602553170.036
stem cell proliferationGO:007208940.036
response to chemicalGO:00422213200.036
ion transportGO:00068111140.035
organic cyclic compound metabolic processGO:19013603010.035
organic cyclic compound biosynthetic processGO:19013622230.035
gene expressionGO:00104672520.035
thioester biosynthetic processGO:003538410.035
transportGO:00068102200.035
alpha amino acid metabolic processGO:190160530.034
macromolecule biosynthetic processGO:00090592270.034
regulation of nitrogen compound metabolic processGO:00511712510.034
regulation of metabolic processGO:00192223590.033
cellular nitrogen compound metabolic processGO:00346412900.033
regulation of cell shapeGO:000836010.033
organic substance biosynthetic processGO:19015762890.033
positive regulation of cellular amino acid metabolic processGO:004576400.032
cellular component assemblyGO:00226071700.032
nuclear transportGO:005116940.031
regulation of peptidyl tyrosine phosphorylationGO:005073010.031
positive regulation of cellular catabolic processGO:003133130.030
ion transmembrane transportGO:0034220910.030
spermatid developmentGO:000728620.029
regulation of primary metabolic processGO:00800903110.029
regulation of multicellular organismal processGO:00512392770.029
cation transmembrane transportGO:0098655650.028
negative regulation of heart contractionGO:004582220.028
inorganic cation transmembrane transportGO:0098662500.028
regulation of reproductive processGO:200024140.028
cellular aromatic compound metabolic processGO:00067252950.028
cellular amino acid metabolic processGO:000652070.027
regulation of cellular amino acid metabolic processGO:000652100.027
regulation of epithelial cell proliferationGO:005067830.027
regulation of cellular amine metabolic processGO:003323800.026
immune system processGO:00023762410.026
negative regulation of protein phosphorylationGO:000193340.026
positive regulation of cellular processGO:00485222010.026
embryonic organ developmentGO:00485683810.026
organelle organizationGO:00069962270.025
synaptic growth at neuromuscular junctionGO:005112420.025
cellular response to extracellular stimulusGO:003166820.025
negative regulation of protein kinase activityGO:000646940.025
atp synthesis coupled electron transportGO:004277310.025
heterocycle metabolic processGO:00464832900.024
cellular nitrogen compound biosynthetic processGO:00442712180.024
macromolecular complex assemblyGO:0065003350.024
cellular lipid catabolic processGO:004424230.024
regulation of establishment of protein localizationGO:007020140.024
response to stressGO:00069502630.023
deathGO:00162651210.023
phagocytosis engulfmentGO:000691110.023
regulation of rna metabolic processGO:00512522240.023
regulation of multicellular organismal developmentGO:20000262230.023
regulation of cellular ketone metabolic processGO:001056570.023
striated muscle cell developmentGO:00550021080.023
modification dependent protein catabolic processGO:001994130.023
angiogenesisGO:00015251580.023
protein import into nucleusGO:000660630.023
lipid storageGO:001991510.022
single organism nuclear importGO:190259330.022
nucleobase containing compound biosynthetic processGO:00346542050.022
positive regulation of cell adhesionGO:004578510.022
cell projection organizationGO:00300302840.022
digestive tract developmentGO:00485652650.022
regulation of neural precursor cell proliferationGO:200017730.022
muscle structure developmentGO:00610611960.022
cell motilityGO:00488702440.022
taxisGO:00423301090.021
regulation of metal ion transportGO:001095940.021
programmed cell deathGO:00125011190.021
cellular biosynthetic processGO:00442492860.021
negative regulation of kinase activityGO:003367340.021
establishment of protein localization to organelleGO:007259440.021
regulation of protein transportGO:005122330.021
positive regulation of muscle cell differentiationGO:005114910.021
amino acid transportGO:000686520.021
somatic muscle developmentGO:000752540.020
nucleic acid transportGO:005065720.020
oocyte maturationGO:000155640.020
biosynthetic processGO:00090582940.020
nitrogen compound metabolic processGO:00068073190.020
positive regulation of cellular component biogenesisGO:004408930.020
nucleocytoplasmic transportGO:000691340.020
cellular carbohydrate metabolic processGO:004426240.020
cellular response to nutrient levelsGO:003166920.019
regulation of nucleobase containing compound metabolic processGO:00192192500.019
multicellular organismal metabolic processGO:004423620.019
nucleic acid metabolic processGO:00903042440.019
purine ribonucleoside monophosphate catabolic processGO:000916940.019
positive regulation of cell activationGO:005086710.019
eye developmentGO:00016542770.019
regulation of protein targetingGO:190353320.019
positive regulation of translationGO:004572710.019
cellular protein metabolic processGO:00442671290.019
response to woundingGO:00096111160.019
regulation of stem cell differentiationGO:200073640.019
protein complex disassemblyGO:004324110.019
adult behaviorGO:003053420.019
neurotransmitter transportGO:000683620.019
spermatid differentiationGO:004851520.019
positive regulation of nitrogen compound metabolic processGO:0051173690.019
nucleoside monophosphate catabolic processGO:000912540.019
regulation of cellular macromolecule biosynthetic processGO:20001122220.019
cellular component morphogenesisGO:00329893360.019
determination of bilateral symmetryGO:00098552040.019
cell deathGO:00082191210.019
digestive tract morphogenesisGO:00485462310.018
protein polymerizationGO:005125840.018
single organism transportGO:00447652060.018
modification dependent macromolecule catabolic processGO:004363230.018
regulation of developmental processGO:00507932470.018
symbiosis encompassing mutualism through parasitismGO:004440340.018
regulation of nucleocytoplasmic transportGO:004682220.018
regulation of biosynthetic processGO:00098892500.018
cellular component biogenesisGO:00440851780.018
protein methylationGO:0006479130.018
single organism biosynthetic processGO:0044711710.018
organic acid catabolic processGO:001605430.018
protein importGO:001703830.018
nuclear importGO:005117030.018
positive regulation of metabolic processGO:00098931080.017
purine nucleoside triphosphate biosynthetic processGO:000914520.017
i kappab kinase nf kappab signalingGO:000724940.017
alcohol biosynthetic processGO:004616520.017
regulation of intracellular protein transportGO:003315730.017
positive regulation of cellular amine metabolic processGO:003324000.017
electron transport chainGO:002290020.017
transcription dna templatedGO:00063511810.017
macromolecular complex subunit organizationGO:0043933740.017
cell substrate adhesionGO:003158940.017
tissue remodelingGO:004877140.017
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.016
cellular ketone metabolic processGO:0042180110.016
meiotic nuclear divisionGO:000712640.016
chordate embryonic developmentGO:00430092710.016
developmental growthGO:00485891660.016
branched chain amino acid metabolic processGO:000908110.016
protein acylationGO:004354330.016
sensory organ developmentGO:00074233930.016
negative regulation of catabolic processGO:000989530.016
regulation of signalingGO:00230512350.016
response to drugGO:004249330.016
embryonic hemopoiesisGO:0035162530.016
negative regulation of cellular processGO:00485232830.016
regulation of protein catabolic processGO:004217610.016
cofactor biosynthetic processGO:0051188100.016
oxidative phosphorylationGO:000611910.016
mononuclear cell proliferationGO:003294310.016
proteolysis involved in cellular protein catabolic processGO:005160330.016
cellular response to stressGO:0033554620.016
tissue regenerationGO:0042246740.016
apoptotic processGO:00069151160.016
cognitionGO:005089010.016
insulin like growth factor receptor signaling pathwayGO:004800940.016
macromolecular complex disassemblyGO:003298410.016
inorganic ion transmembrane transportGO:0098660570.015
fatty acid beta oxidationGO:000663510.015
regulation of dna templated transcription in response to stressGO:004362000.015
heart developmentGO:00075073130.015
metal ion transportGO:0030001580.015
skeletal system developmentGO:00015011810.015
regulation of fatty acid metabolic processGO:001921710.015
calcium mediated signalingGO:001972220.015
protein targeting to nucleusGO:004474430.015
lipid oxidationGO:003444010.015
meiotic cell cycle processGO:190304630.015
energy reserve metabolic processGO:000611220.015
determination of heart left right asymmetryGO:00613711170.015
heterocycle biosynthetic processGO:00181302150.015
cellular response to starvationGO:000926710.015
cellular response to external stimulusGO:007149620.015
regulation of intracellular phGO:005145310.015
regulation of rna biosynthetic processGO:20011412130.015
negative regulation of macromolecule metabolic processGO:0010605760.015
cellular response to unfolded proteinGO:003462020.015
positive regulation of epithelial cell migrationGO:001063420.015
organophosphate biosynthetic processGO:0090407230.015
response to external biotic stimulusGO:0043207970.015
ubiquitin dependent protein catabolic processGO:000651130.015
single organism organelle organizationGO:19025891990.014
regulation of cell deathGO:00109411030.014
cellular macromolecule biosynthetic processGO:00346452240.014
rna transportGO:005065820.014
aromatic compound biosynthetic processGO:00194382170.014
generation of neuronsGO:00486993850.014
positive regulation of cell cycleGO:004578730.014
neuron projection developmentGO:00311751800.014
system processGO:00030081850.014
embryonic heart tube developmentGO:00350501330.014
regulation of receptor activityGO:001046920.014
regulation of programmed cell deathGO:00430671010.014
regulation of anatomical structure morphogenesisGO:00226031300.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
chemosensory behaviorGO:000763510.014
homeostatic processGO:00425921420.014
regulation of cell activationGO:005086510.014
negative regulation of metabolic processGO:0009892860.014
multi organism cellular processGO:004476420.014
brain developmentGO:00074202930.014
leukocyte proliferationGO:007066110.014
neurotransmitter secretionGO:000726920.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
purine nucleoside monophosphate catabolic processGO:000912840.014
protein dephosphorylationGO:000647030.013
negative regulation of multicellular organismal processGO:0051241690.013
response to unfolded proteinGO:000698620.013
peptidyl threonine phosphorylationGO:001810710.013
monovalent inorganic cation transportGO:0015672420.013
cofactor metabolic processGO:0051186150.013
posttranscriptional gene silencing by rnaGO:003519430.013
regulation of oocyte developmentGO:006028130.013
regulation of macromolecule biosynthetic processGO:00105562250.013
multi organism processGO:00517041340.013
cellular component maintenanceGO:004395430.013
regulation of protein localization to nucleusGO:190018020.013
branching morphogenesis of a nerveGO:004875540.013
nucleic acid templated transcriptionGO:00976591810.013
actin polymerization or depolymerizationGO:000815420.013
negative regulation of cytokine productionGO:000181810.013
fatty acid oxidationGO:001939510.013
carbohydrate biosynthetic processGO:001605110.013
epithelial cell morphogenesisGO:000338220.013
negative regulation of cytoplasmic transportGO:190365020.013
positive regulation of macromolecule metabolic processGO:0010604930.013
lymphocyte proliferationGO:004665110.013
regulation of muscle contractionGO:000693730.013
regulation of signal transductionGO:00099662250.013
monocarboxylic acid catabolic processGO:007232930.013
central nervous system developmentGO:00074173870.013
regulation of cell migrationGO:0030334400.013
heart morphogenesisGO:00030071560.013
positive regulation of protein polymerizationGO:003227320.013
regulation of erk1 and erk2 cascadeGO:007037240.013
regulation of mrna catabolic processGO:006101330.013
heart loopingGO:0001947940.013
nuclear exportGO:005116810.013
specification of organ axis polarityGO:001008420.013
regulation of dna replicationGO:000627530.013
wound healingGO:0042060900.013
regulation of protein polymerizationGO:003227120.012
positive regulation of cellular metabolic processGO:0031325940.012
phosphorus metabolic processGO:00067931090.012
rna biosynthetic processGO:00327741810.012
sprouting angiogenesisGO:0002040530.012
receptor internalizationGO:003162320.012
gtp metabolic processGO:004603940.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
organelle assemblyGO:00709251100.012
protein acetylationGO:000647320.012
establishment of rna localizationGO:005123630.012
embryonic organ morphogenesisGO:00485622740.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.012
thioester metabolic processGO:003538310.012
lipid catabolic processGO:001604240.012
regulation of cell substrate adhesionGO:001081010.012
regulation of cell maturationGO:190342910.012
regulation of mrna processingGO:005068430.012
carbohydrate homeostasisGO:003350010.012
regulation of cytoplasmic transportGO:190364940.012
cell morphogenesisGO:00009022890.012
regulation of cardiac muscle contractionGO:005511720.012
regulation of neuron projection developmentGO:0010975400.012
regulation of transmembrane transporter activityGO:002289820.012
respiratory electron transport chainGO:002290420.012
positive regulation of dna metabolic processGO:005105410.012
chemotaxisGO:00069351040.012
peptidyl serine phosphorylationGO:001810510.012
negative regulation of blood circulationGO:190352320.012
stem cell maintenanceGO:001982740.012
tube closureGO:006060610.012
extracellular matrix organizationGO:0030198270.012
purine ribonucleoside triphosphate biosynthetic processGO:000920620.012
positive regulation of cytoskeleton organizationGO:005149530.012
skeletal system morphogenesisGO:00487051020.012
regulation of synaptic plasticityGO:004816710.012
negative regulation of epithelial cell proliferationGO:005068010.012
intracellular signal transductionGO:0035556850.011
regulation of cellular component organizationGO:0051128860.011
response to vitaminGO:003327330.011
negative regulation of immune responseGO:005077720.011
digestive system developmentGO:00551232890.011
double strand break repairGO:000630230.011
nucleoside biosynthetic processGO:000916320.011
regulation of locomotionGO:0040012550.011
methylationGO:0032259220.011
fatty acid transportGO:001590810.011
muscle cell developmentGO:00550011150.011
regulation of sodium ion transportGO:000202820.011
regulation of neurotransmitter transportGO:005158810.011
peptidyl serine modificationGO:001820920.011
regulation of cellular component movementGO:0051270550.011
small molecule catabolic processGO:004428230.011
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.011
cellular monovalent inorganic cation homeostasisGO:003000420.011
protein localization to nucleusGO:003450430.011
interspecies interaction between organismsGO:004441940.011
positive regulation of blood circulationGO:190352420.011
positive regulation of nucleotide catabolic processGO:003081310.011
negative regulation of cellular catabolic processGO:003133030.011
regulation of myotube differentiationGO:001083020.011
regulation of i kappab kinase nf kappab signalingGO:004312240.011
positive regulation of nucleoside metabolic processGO:004597910.011
catabolic processGO:0009056320.011
sulfur compound biosynthetic processGO:004427290.011
neuron developmentGO:00486662620.011
regulation of protein ubiquitinationGO:003139630.011
centrosome organizationGO:005129710.011
cellular component assembly involved in morphogenesisGO:00109271070.011
response to alkaloidGO:004327920.011
regulation of cellular biosynthetic processGO:00313262450.011
cellular response to chemical stimulusGO:00708871570.011
skeletal muscle tissue developmentGO:0007519670.011
er nucleus signaling pathwayGO:000698420.011
negative regulation of dna metabolic processGO:005105340.011
sleepGO:003043110.011
fatty acid catabolic processGO:000906210.011
ribonucleoside monophosphate catabolic processGO:000915840.011
microtubule organizing center organizationGO:003102310.011
regulation of transporter activityGO:003240920.011
regulation of nucleoside metabolic processGO:000911820.011
positive regulation of cell substrate adhesionGO:001081110.011
positive regulation of stem cell proliferationGO:200064810.011
anion transportGO:0006820380.011
response to abiotic stimulusGO:00096281220.010
positive regulation of striated muscle cell differentiationGO:005115510.010
positive regulation of dna templated transcription elongationGO:003278610.010
actin filament polymerizationGO:003004120.010
epithelial tube morphogenesisGO:00605621480.010
primary neural tube formationGO:001402010.010
erythrocyte homeostasisGO:0034101550.010
response to nutrientGO:000758430.010
germ cell developmentGO:0007281220.010
adherens junction organizationGO:003433240.010
purine ribonucleoside biosynthetic processGO:004612920.010
gene silencingGO:001645840.010
regulation of cellular carbohydrate metabolic processGO:001067540.010
cellular response to organic substanceGO:00713101050.010
guanosine containing compound metabolic processGO:190106840.010
cell proliferationGO:0008283800.010
g2 m transition of mitotic cell cycleGO:000008640.010
cellular response to decreased oxygen levelsGO:003629410.010
axon developmentGO:00615641660.010
negative regulation of apoptotic processGO:0043066550.010
cellular protein catabolic processGO:004425740.010
positive regulation of striated muscle tissue developmentGO:004584410.010
guanosine containing compound catabolic processGO:190106920.010
dna templated transcription elongationGO:000635430.010
cellular amide metabolic processGO:004360340.010
dorsal ventral pattern formationGO:00099531250.010
negative regulation of multi organism processGO:004390130.010

ogdh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.079
inherited metabolic disorderDOID:65500.079
disease of anatomical entityDOID:700.041
nervous system diseaseDOID:86300.034
musculoskeletal system diseaseDOID:1700.022
connective tissue diseaseDOID:6500.019
bone diseaseDOID:008000100.014
organ system cancerDOID:005068600.013
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
cardiovascular system diseaseDOID:128700.011
myopathyDOID:42300.011
muscle tissue diseaseDOID:6600.011
muscular diseaseDOID:008000000.011
intrinsic cardiomyopathyDOID:006003600.010
heart diseaseDOID:11400.010
cardiomyopathyDOID:005070000.010
neurodegenerative diseaseDOID:128900.010
central nervous system diseaseDOID:33100.010