Danio rerio

14 known processes

p2rx2

purinergic receptor P2X, ligand-gated ion channel, 2

(Aliases: p2xr2)

p2rx2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory perception of chemical stimulusGO:000760630.406
Mouse
cation transmembrane transportGO:0098655650.402
transmembrane transportGO:00550851200.332
protein heterooligomerizationGO:005129110.224
Zebrafish Rat
axon guidanceGO:0007411860.222
cell projection organizationGO:00300302840.187
regulation of biological qualityGO:00650082630.169
Mouse Rat
multicellular organismal response to stressGO:003355520.162
Mouse
developmental cell growthGO:0048588520.151
mechanosensory behaviorGO:000763820.142
regulation of calcium mediated signalingGO:005084810.142
response to external stimulusGO:00096052640.137
cell part morphogenesisGO:00329902460.135
response to chemicalGO:00422213200.128
Mouse
taxisGO:00423301090.119
sympathetic nervous system developmentGO:004848530.113
cell projection morphogenesisGO:00488582440.111
ion transportGO:00068111140.107
developmental growth involved in morphogenesisGO:0060560860.107
axon developmentGO:00615641660.106
regulation of circadian rhythmGO:004275240.101
cell morphogenesis involved in neuron differentiationGO:00486671630.101
ion transmembrane transportGO:0034220910.098
detection of chemical stimulusGO:000959340.097
Mouse
neuron differentiationGO:00301823530.096
axonogenesisGO:00074091520.095
cellular component movementGO:00069283350.094
detection of mechanical stimulus involved in sensory perceptionGO:0050974110.092
single organism transportGO:00447652060.086
embryonic organ developmentGO:00485683810.084
hair cell differentiationGO:0035315320.083
neuron developmentGO:00486662620.080
response to hydrogen peroxideGO:004254230.080
neuron projection guidanceGO:0097485860.077
cellular component morphogenesisGO:00329893360.076
cell morphogenesis involved in differentiationGO:00009041950.075
cell morphogenesisGO:00009022890.075
locus ceruleus developmentGO:002170330.073
positive regulation of biological processGO:00485182530.072
chemotaxisGO:00069351040.070
regulation of multicellular organismal processGO:00512392770.070
inner ear receptor cell differentiationGO:0060113290.069
establishment of localizationGO:00512342440.069
phototransductionGO:000760220.066
response to temperature stimulusGO:0009266150.066
regulation of cell developmentGO:00602841000.066
nucleobase containing compound biosynthetic processGO:00346542050.066
neuron projection morphogenesisGO:00488121610.065
regulation of signal transductionGO:00099662250.062
generation of neuronsGO:00486993850.061
sensory perception of painGO:001923310.059
regulation of synaptic plasticityGO:004816710.058
response to carbohydrateGO:000974330.058
Mouse
neuromuscular synaptic transmissionGO:000727420.058
Mouse
single organism localizationGO:19025782250.058
regulation of neuron differentiationGO:0045664560.057
regulation of cell morphogenesis involved in differentiationGO:0010769380.057
stem cell proliferationGO:007208940.057
localization of cellGO:00516742440.054
appendage morphogenesisGO:0035107560.054
response to coldGO:000940940.054
cell motilityGO:00488702440.053
cellular response to chemical stimulusGO:00708871570.052
Mouse
chemosensory behaviorGO:000763510.051
response to drugGO:004249330.051
detection of temperature stimulusGO:001604800.050
inorganic ion transmembrane transportGO:0098660570.049
regulation of axonogenesisGO:0050770320.049
regulation of cell communicationGO:00106462320.048
regulation of axon extensionGO:0030516240.048
response to inorganic substanceGO:0010035380.047
positive regulation of cellular processGO:00485222010.047
embryonic organ morphogenesisGO:00485622740.047
regulation of macromolecule metabolic processGO:00602553170.046
establishment of epithelial cell polarityGO:009016220.045
regulation of cell differentiationGO:00455951420.044
central nervous system developmentGO:00074173870.044
neuron projection extensionGO:1990138450.044
calcium mediated signalingGO:001972220.044
cell surface receptor signaling pathwayGO:00071663250.043
locomotionGO:00400113130.043
regulation of signalingGO:00230512350.043
regulation of response to stimulusGO:00485832690.043
detection of mechanical stimulusGO:0050982110.042
cranial nerve developmentGO:0021545420.042
response to abiotic stimulusGO:00096281220.041
Mouse
synaptic vesicle transportGO:004848910.041
autonomic nervous system developmentGO:0048483190.041
organic cyclic compound biosynthetic processGO:19013622230.040
polarized epithelial cell differentiationGO:003085940.040
brain developmentGO:00074202930.039
gene expressionGO:00104672520.039
sensory perception of mechanical stimulusGO:0050954160.039
Human Mouse
medulla oblongata developmentGO:002155040.038
transmission of nerve impulseGO:0019226190.038
Rat
response to mechanical stimulusGO:0009612240.038
regulation of cellular component organizationGO:0051128860.037
transportGO:00068102200.037
response to heatGO:000940860.037
sensory organ developmentGO:00074233930.037
neuron projection developmentGO:00311751800.037
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.037
morphogenesis of an epitheliumGO:00020093330.036
developmental programmed cell deathGO:001062340.036
regulation of neuron projection developmentGO:0010975400.036
nitrogen compound metabolic processGO:00068073190.036
regulation of cell morphogenesisGO:0022604420.036
connective tissue developmentGO:0061448990.035
sympathetic ganglion developmentGO:006154920.035
signal transductionGO:00071654550.035
semicircular canal developmentGO:0060872240.035
response to radiationGO:0009314510.034
striated muscle tissue developmentGO:00147061100.034
Mouse
inner ear developmentGO:00488391260.034
neuroblast proliferationGO:000740520.034
cartilage developmentGO:0051216960.033
stem cell maintenanceGO:001982740.033
system processGO:00030081850.033
Human Mouse Rat
adherens junction maintenanceGO:003433420.033
neuron migrationGO:0001764220.032
camera type eye morphogenesisGO:00485931080.032
axon extensionGO:0048675450.032
response to organic substanceGO:00100331530.032
Mouse
regulation of developmental processGO:00507932470.032
cellular biosynthetic processGO:00442492860.032
inner ear morphogenesisGO:0042472630.032
inorganic cation transmembrane transportGO:0098662500.032
camera type eye developmentGO:00430102220.031
phagocytosisGO:000690930.031
regulation of neurogenesisGO:0050767870.031
renal system developmentGO:0072001940.030
establishment of synaptic vesicle localizationGO:009748010.030
midbrain developmentGO:0030901280.030
positive regulation of transportGO:005105020.030
regionalizationGO:00030022740.030
anterior posterior pattern specificationGO:00099521520.030
epidermis developmentGO:0008544480.030
regulation of cellular biosynthetic processGO:00313262450.030
regulation of metabolic processGO:00192223590.030
sensory organ morphogenesisGO:00905962000.030
digestive system developmentGO:00551232890.030
agingGO:000756820.029
cell migrationGO:00164772370.029
hindbrain developmentGO:0030902910.029
monovalent inorganic cation transportGO:0015672420.029
stem cell divisionGO:001714510.029
female sex differentiationGO:004666040.028
ear developmentGO:00435831270.028
regulation of multicellular organismal developmentGO:20000262230.028
larval developmentGO:000216420.028
stem cell differentiationGO:00488631170.028
neurological system processGO:0050877620.028
Human Mouse Rat
rhombomere 5 developmentGO:002157140.028
skin developmentGO:0043588540.027
pectoral fin morphogenesisGO:0035138290.027
regulation of nitrogen compound metabolic processGO:00511712510.027
mesenchyme developmentGO:00604851270.027
sodium ion transportGO:0006814240.027
multicellular organismal signalingGO:0035637220.026
Rat
eye morphogenesisGO:00485921440.026
cellular component biogenesisGO:00440851780.026
Human Zebrafish Rat
regulation of multicellular organism growthGO:004001440.026
regulation of macromolecule biosynthetic processGO:00105562250.026
regulation of photoreceptor cell differentiationGO:004653220.026
synaptic vesicle localizationGO:009747910.026
regulation of cell growthGO:0001558290.026
smooth muscle contractionGO:000693920.026
Mouse
adult behaviorGO:003053420.026
developmental growthGO:00485891660.026
cellular macromolecule metabolic processGO:00442603910.026
anatomical structure arrangementGO:004853220.025
kidney developmentGO:0001822920.025
female gonad developmentGO:000858540.025
heterocycle metabolic processGO:00464832900.025
cell growthGO:0016049570.025
inner ear receptor cell developmentGO:0060119200.025
epithelial cell differentiationGO:00308551160.024
cellular response to organic substanceGO:00713101050.024
cellular component assemblyGO:00226071700.024
Human Zebrafish Rat
cellular amine metabolic processGO:004410620.024
cellular response to methanolGO:007140540.024
regulation of nervous system developmentGO:0051960900.024
macromolecule biosynthetic processGO:00090592270.024
sensory perceptionGO:0007600390.024
Human Mouse
cellular component disassemblyGO:002241110.023
nerve developmentGO:0021675450.023
sprouting angiogenesisGO:0002040530.023
response to monosaccharideGO:003428430.023
pronephros developmentGO:0048793690.023
organic substance biosynthetic processGO:19015762890.023
regulation of extent of cell growthGO:0061387290.023
mechanoreceptor differentiationGO:0042490370.022
neuronal action potentialGO:0019228180.022
Rat
cellular component maintenanceGO:004395430.022
retina development in camera type eyeGO:00600411460.022
peripheral nervous system developmentGO:0007422550.022
cell substrate adhesionGO:003158940.022
negative regulation of biological processGO:00485193040.022
cell matrix adhesionGO:000716040.022
regulation of peptidyl tyrosine phosphorylationGO:005073010.022
mesenchymal cell differentiationGO:0048762870.022
angiogenesisGO:00015251580.021
protein metabolic processGO:00195381830.021
gtp metabolic processGO:004603940.021
cartilage condensationGO:000150230.021
pons developmentGO:0021548110.021
behaviorGO:0007610740.021
Mouse
positive regulation of cell adhesionGO:004578510.021
response to stressGO:00069502630.021
Mouse
detection of chemical stimulus involved in sensory perceptionGO:005090730.021
olfactory lobe developmentGO:002198840.021
detection of external stimulusGO:0009581240.021
cation transportGO:0006812810.020
collateral sprouting in absence of injuryGO:004866940.020
amine metabolic processGO:000930820.020
action potentialGO:0001508190.020
Rat
positive regulation of protein complex assemblyGO:003133420.020
cell cycle arrestGO:000705010.020
regulation of stem cell differentiationGO:200073640.020
detection of stimulusGO:0051606290.020
Mouse
branching morphogenesis of a nerveGO:004875540.020
detection of temperature stimulus involved in sensory perceptionGO:005096100.020
fin developmentGO:0033333770.020
neural tube developmentGO:0021915620.020
cellular aromatic compound metabolic processGO:00067252950.020
adherens junction organizationGO:003433240.019
rhombomere 6 developmentGO:002157240.019
regulation of cell projection organizationGO:0031344440.019
developmental pigmentationGO:0048066480.019
forebrain cell migrationGO:002188510.019
glucose homeostasisGO:004259310.019
digestive tract morphogenesisGO:00485462310.019
regulation of tube sizeGO:003515020.019
regulation of mrna processingGO:005068430.019
response to reactive oxygen speciesGO:000030250.019
carbohydrate biosynthetic processGO:001605110.019
segmentationGO:0035282970.019
tube morphogenesisGO:00352393490.019
regulation of jak stat cascadeGO:004642530.019
metencephalon developmentGO:0022037270.019
epidermal cell differentiationGO:0009913360.019
neurotransmitter transportGO:000683620.019
neurotransmitter secretionGO:000726920.018
urogenital system developmentGO:0001655970.018
regulation of cellular macromolecule biosynthetic processGO:20001122220.018
type b pancreatic cell developmentGO:000332340.018
metal ion transportGO:0030001580.018
muscle organ developmentGO:00075171010.018
Mouse
homeostatic processGO:00425921420.018
regulation of cellular component movementGO:0051270550.018
neuromuscular process controlling balanceGO:005088530.018
protein complex biogenesisGO:0070271300.018
Human Zebrafish Rat
development of primary female sexual characteristicsGO:004654540.018
epithelial tube morphogenesisGO:00605621480.018
response to oxygen containing compoundGO:1901700550.018
Mouse
cellular nitrogen compound metabolic processGO:00346412900.018
regulation of reproductive processGO:200024140.018
skeletal system developmentGO:00015011810.018
regulation of gene expressionGO:00104682650.018
autophagyGO:000691440.018
skeletal system morphogenesisGO:00487051020.018
chordate embryonic developmentGO:00430092710.018
cell aggregationGO:009874330.018
eye developmentGO:00016542770.018
positive regulation of cellular component biogenesisGO:004408930.018
vasculature developmentGO:00019442780.018
peptidyl threonine modificationGO:001821010.017
regulation of cellular carbohydrate metabolic processGO:001067540.017
pancreatic d cell differentiationGO:000331120.017
tissue remodelingGO:004877140.017
response to oxidative stressGO:0006979110.017
synaptic vesicle recyclingGO:003646510.017
regulation of meiotic cell cycleGO:005144510.017
multi organism processGO:00517041340.017
negative regulation of mapk cascadeGO:004340940.017
carboxylic acid metabolic processGO:0019752220.017
spermatid developmentGO:000728620.017
regulation of purine nucleotide catabolic processGO:003312120.017
carbohydrate homeostasisGO:003350010.017
multicellular organism growthGO:003526440.017
regulation of cellular ketone metabolic processGO:001056570.017
somatic muscle developmentGO:000752540.017
regulation of cell sizeGO:0008361290.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
regulation of nucleotide catabolic processGO:003081120.017
swimming behaviorGO:003626980.017
oxoacid metabolic processGO:0043436310.016
regulation of cellular component sizeGO:0032535300.016
extrinsic apoptotic signaling pathwayGO:009719130.016
semicircular canal morphogenesisGO:0048752180.016
post embryonic organ developmentGO:004856940.016
thermosensory behaviorGO:004004010.016
regulation of cytokine productionGO:000181730.016
organonitrogen compound metabolic processGO:1901564740.016
compound eye developmentGO:004874920.016
aromatic compound biosynthetic processGO:00194382170.016
neural crest cell differentiationGO:0014033720.016
cell junction maintenanceGO:003433120.016
hormone transportGO:000991420.016
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.016
regulation of nucleobase containing compound metabolic processGO:00192192500.016
regulation of bindingGO:005109830.016
positive regulation of cell cycleGO:004578730.016
regulation of phGO:000688530.016
regulation of extrinsic apoptotic signaling pathwayGO:200123630.016
positive regulation of nervous system developmentGO:0051962250.016
atp catabolic processGO:000620040.016
macromolecular complex disassemblyGO:003298410.016
regulation of biosynthetic processGO:00098892500.016
protein homooligomerizationGO:005126030.016
Human Rat
cellular macromolecule biosynthetic processGO:00346452240.016
regulation of stem cell proliferationGO:007209120.016
regulation of developmental growthGO:0048638380.016
ribonucleoside monophosphate catabolic processGO:000915840.016
positive regulation of cellular catabolic processGO:003133130.016
muscle structure developmentGO:00610611960.016
Mouse
regulation of protein catabolic processGO:004217610.016
lateral inhibitionGO:004633110.016
muscle tissue developmentGO:00605371100.016
Mouse
organic cyclic compound metabolic processGO:19013603010.015
blood circulationGO:0008015870.015
Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.015
spermatid differentiationGO:004851520.015
pectoral fin developmentGO:0033339500.015
neural crest cell migrationGO:0001755420.015
epithelial cell developmentGO:0002064420.015
ameboidal type cell migrationGO:00016671430.015
regulation of protein complex assemblyGO:004325430.015
regulation of nucleoside metabolic processGO:000911820.015
apoptotic process involved in developmentGO:190274220.015
regulation of cell motilityGO:2000145460.015
cilium morphogenesisGO:0060271850.015
regulation of glucose transportGO:001082710.015
synaptic vesicle endocytosisGO:004848810.015
cellular ketone metabolic processGO:0042180110.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
negative regulation of chemotaxisGO:005092240.015
cognitionGO:005089010.015
regulation of neural precursor cell proliferationGO:200017730.015
regulation of neuron migrationGO:200122220.015
embryonic pectoral fin morphogenesisGO:0035118240.015
protein localization to plasma membraneGO:007265910.015
regulation of cytoplasmic transportGO:190364940.015
trigeminal nerve developmentGO:002155930.015
appendage developmentGO:0048736800.015
enteric nervous system developmentGO:0048484120.014
transcription from rna polymerase ii promoterGO:0006366800.014
locomotor rhythmGO:004547530.014
guanosine containing compound catabolic processGO:190106920.014
sequestering of metal ionGO:005123830.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
heterocycle biosynthetic processGO:00181302150.014
regulation of transcription dna templatedGO:00063552130.014
auditory receptor cell differentiationGO:0042491150.014
proteasomal protein catabolic processGO:001049820.014
protein polymerizationGO:005125840.014
regulation of primary metabolic processGO:00800903110.014
collateral sproutingGO:004866890.014
cellular carbohydrate metabolic processGO:004426240.014
sodium ion transmembrane transportGO:0035725210.014
actin polymerization or depolymerizationGO:000815420.014
protein oligomerizationGO:005125970.014
Human Zebrafish Rat
lipid storageGO:001991510.014
rna localizationGO:000640340.014
regulation of carbohydrate metabolic processGO:000610940.014
stem cell developmentGO:0048864820.014
embryo development ending in birth or egg hatchingGO:00097922710.014
regulation of protein depolymerizationGO:190187910.014
response to uvGO:000941130.014
mesenchymal cell developmentGO:0014031780.014
auditory receptor cell developmentGO:006011780.014
otolith developmentGO:0048840320.014
meiotic cell cycle processGO:190304630.014
regulation of systemic arterial blood pressureGO:000307310.014
Mouse
response to copper ionGO:0046688130.014
regulation of cell activationGO:005086510.014
germ line stem cell maintenanceGO:003071820.014
golgi vesicle transportGO:004819330.014
phasic smooth muscle contractionGO:001482110.014
Mouse
positive regulation of epithelial cell differentiationGO:003085820.014
heart contractionGO:0060047710.013
cellular response to reactive oxygen speciesGO:003461420.013
nucleic acid metabolic processGO:00903042440.013
regulation of blood vessel sizeGO:005088020.013
regulation of gtp catabolic processGO:003312420.013
negative chemotaxisGO:005091910.013
cellular response to extracellular stimulusGO:003166820.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
establishment of protein localization to plasma membraneGO:009000210.013
mesendoderm developmentGO:0048382100.013
response to topologically incorrect proteinGO:003596620.013
spinal cord developmentGO:0021510460.013
morphogenesis of an epithelial sheetGO:0002011490.013
entrainment of circadian clockGO:000964920.013
protein complex disassemblyGO:004324110.013
intracellular signal transductionGO:0035556850.013
muscle system processGO:0003012200.013
Mouse
regulation of dendrite developmentGO:005077330.013
embryonic eye morphogenesisGO:0048048300.013
embryonic skeletal joint morphogenesisGO:006027230.013
positive regulation of secretionGO:005104710.013
embryonic skeletal joint developmentGO:007249830.013
regulation of protein transportGO:005122330.013
regulation of metal ion transportGO:001095940.013
guanosine containing compound metabolic processGO:190106840.013
regulation of dendrite morphogenesisGO:004881430.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
epibolyGO:0090504410.013
regulation of cell migrationGO:0030334400.012
regulation of anatomical structure morphogenesisGO:00226031300.012
regulation of glucose importGO:004632410.012
tube closureGO:006060610.012
somite developmentGO:0061053960.012
regulation of neuronal synaptic plasticityGO:004816810.012
transcription dna templatedGO:00063511810.012
larval behaviorGO:003053750.012
positive regulation of secretion by cellGO:190353210.012
regulation of cellular phGO:003064110.012
heart developmentGO:00075073130.012
larval heart developmentGO:000750820.012
nucleobase containing compound metabolic processGO:00061392740.012
proteolysis involved in cellular protein catabolic processGO:005160330.012
hepaticobiliary system developmentGO:0061008980.012
regulation of establishment of protein localizationGO:007020140.012
dorsal ventral pattern formationGO:00099531250.012
rna biosynthetic processGO:00327741810.012
regulation of synapse organizationGO:005080730.012
peristalsisGO:003043210.012
Mouse
establishment of vesicle localizationGO:0051650240.012
outflow tract morphogenesisGO:000315110.012
positive regulation of macromolecule metabolic processGO:0010604930.012
positive regulation of catabolic processGO:000989640.012
regulation of protein complex disassemblyGO:004324410.012
regulation of molecular functionGO:0065009700.012
regulation of cellular amine metabolic processGO:003323800.012
regulation of synaptic vesicle transportGO:190280310.012
fin morphogenesisGO:0033334530.012
calcium ion transportGO:0006816180.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
cellular amide metabolic processGO:004360340.012
regulation of muscle contractionGO:000693730.012
embryonic retina morphogenesis in camera type eyeGO:0060059220.012
regulation of protein bindingGO:004339330.012
negative regulation of cellular processGO:00485232830.012
regulation of cell shapeGO:000836010.012
response to hexoseGO:000974630.012
internal peptidyl lysine acetylationGO:001839320.012
skeletal muscle tissue developmentGO:0007519670.012
Mouse
endocardium formationGO:006021410.012
positive regulation of glucose importGO:004632610.012
response to methanolGO:003398640.012
modification dependent macromolecule catabolic processGO:004363230.012
b cell activationGO:004211320.012
pigment cell developmentGO:007028530.012
type b pancreatic cell differentiationGO:000330980.012
ganglion developmentGO:006154850.012
cellular response to lipopolysaccharideGO:007122230.012
regulation of rna biosynthetic processGO:20011412130.012
synaptic transmission cholinergicGO:000727140.012
pigment cell differentiationGO:0050931380.012
membrane fusionGO:006102520.012
specification of symmetryGO:00097992040.012
b cell differentiationGO:003018310.012
positive regulation of neurogenesisGO:0050769240.012
motor neuron axon guidanceGO:0008045230.011
cellular amino acid metabolic processGO:000652070.011
establishment of epithelial cell apical basal polarityGO:004519820.011
purine nucleoside monophosphate catabolic processGO:000912840.011
pigmentationGO:0043473850.011
macromolecular complex subunit organizationGO:0043933740.011
Human Zebrafish Rat
regulation of ion transmembrane transporter activityGO:003241220.011
regulation of rna metabolic processGO:00512522240.011
dorsal spinal cord developmentGO:002151610.011
inner ear receptor cell fate commitmentGO:006012040.011
response to glucoseGO:000974930.011
meiotic nuclear divisionGO:000712640.011
positive regulation of signalingGO:0023056560.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
positive regulation of signal transductionGO:0009967560.011
retina morphogenesis in camera type eyeGO:0060042790.011
determination of bilateral symmetryGO:00098552040.011
protein targeting to membraneGO:000661210.011
regulation of gtpase activityGO:004308720.011
negative regulation of dna metabolic processGO:005105340.011

p2rx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.061
disease of metabolismDOID:001466700.016
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.015
nervous system diseaseDOID:86300.014
immune system diseaseDOID:291400.012
myopathyDOID:42300.012
musculoskeletal system diseaseDOID:1700.012
muscle tissue diseaseDOID:6600.012
muscular diseaseDOID:008000000.012