Danio rerio

20 known processes

pah

phenylalanine hydroxylase

(Aliases: MGC65981,wu:fb02f10,zgc:65981,cb877)

pah biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:0019752220.478
Worm
alpha amino acid metabolic processGO:190160530.449
Worm
organic acid metabolic processGO:0006082310.357
Worm
organic substance biosynthetic processGO:19015762890.329
Zebrafish Worm
cellular amino acid metabolic processGO:000652070.309
Worm
small molecule metabolic processGO:0044281770.294
Worm
response to chemicalGO:00422213200.279
nitrogen compound metabolic processGO:00068073190.274
Zebrafish Worm
maintenance of locationGO:005123540.261
response to organic substanceGO:00100331530.238
single organism localizationGO:19025782250.229
oxoacid metabolic processGO:0043436310.210
Worm
single organism metabolic processGO:00447102170.207
Zebrafish Mouse Worm
agingGO:000756820.197
Worm
muscle cell developmentGO:00550011150.164
muscle structure developmentGO:00610611960.162
single organism transportGO:00447652060.161
developmental growthGO:00485891660.156
striated muscle cell differentiationGO:00511461290.151
lipid storageGO:001991510.150
multicellular organism growthGO:003526440.143
cellular macromolecule biosynthetic processGO:00346452240.143
regulation of developmental processGO:00507932470.138
regulation of macromolecule metabolic processGO:00602553170.133
regulation of cell differentiationGO:00455951420.132
cellular component assemblyGO:00226071700.130
heterocycle biosynthetic processGO:00181302150.128
Zebrafish
transportGO:00068102200.127
regulation of multicellular organism growthGO:004001440.125
cellular biosynthetic processGO:00442492860.123
Zebrafish Worm
pyruvate metabolic processGO:000609010.119
regulation of cell communicationGO:00106462320.114
regulation of multicellular organismal processGO:00512392770.113
deathGO:00162651210.112
response to endogenous stimulusGO:0009719830.109
cellular component biogenesisGO:00440851780.104
negative regulation of biological processGO:00485193040.102
single organism organelle organizationGO:19025891990.100
carboxylic acid catabolic processGO:004639530.098
Worm
insulin like growth factor receptor signaling pathwayGO:004800940.097
nucleic acid templated transcriptionGO:00976591810.095
regulation of apoptotic processGO:0042981980.095
biosynthetic processGO:00090582940.093
Zebrafish Worm
cytoskeleton organizationGO:0007010960.091
cellular modified amino acid metabolic processGO:000657530.091
regulation of metabolic processGO:00192223590.088
single organism biosynthetic processGO:0044711710.086
Worm
heart developmentGO:00075073130.085
cation transportGO:0006812810.085
striated muscle cell developmentGO:00550021080.084
cellular component assembly involved in morphogenesisGO:00109271070.083
regulation of primary metabolic processGO:00800903110.079
muscle cell differentiationGO:00426921390.076
cellular localizationGO:0051641970.075
larval developmentGO:000216420.075
heterocycle metabolic processGO:00464832900.074
Zebrafish Worm
fat soluble vitamin metabolic processGO:000677540.074
regulation of transcription from rna polymerase ii promoterGO:00063571140.073
cellular amine metabolic processGO:004410620.071
Worm
positive regulation of biological processGO:00485182530.070
locomotionGO:00400113130.070
cellular aromatic compound metabolic processGO:00067252950.069
Zebrafish Worm
organelle assemblyGO:00709251100.068
regulation of nucleic acid templated transcriptionGO:19035062130.066
cellular component morphogenesisGO:00329893360.066
nucleobase containing compound metabolic processGO:00061392740.066
regulation of cellular biosynthetic processGO:00313262450.065
macromolecule biosynthetic processGO:00090592270.065
cellular response to organic substanceGO:00713101050.065
nucleic acid metabolic processGO:00903042440.065
chordate embryonic developmentGO:00430092710.065
protein metabolic processGO:00195381830.064
organic acid catabolic processGO:001605430.064
Worm
proton transportGO:001599270.063
neuron differentiationGO:00301823530.063
Zebrafish
regulation of cellular macromolecule biosynthetic processGO:20001122220.062
alcohol biosynthetic processGO:004616520.061
regulation of response to stimulusGO:00485832690.061
regulation of signalingGO:00230512350.060
signal transductionGO:00071654550.060
embryo development ending in birth or egg hatchingGO:00097922710.060
Worm
response to hormoneGO:0009725480.060
cellular nitrogen compound biosynthetic processGO:00442712180.060
Zebrafish
regulation of cellular metabolic processGO:00313233200.059
positive regulation of cellular processGO:00485222010.059
regulation of rna biosynthetic processGO:20011412130.059
cell deathGO:00082191210.058
immune system processGO:00023762410.058
regulation of nitrogen compound metabolic processGO:00511712510.057
gene expressionGO:00104672520.056
actin filament based processGO:0030029640.056
embryonic organ developmentGO:00485683810.053
cellular ketone metabolic processGO:0042180110.052
muscle tissue developmentGO:00605371100.052
response to stressGO:00069502630.050
Worm
neurotransmitter transportGO:000683620.050
macromolecular complex subunit organizationGO:0043933740.050
regulation of biosynthetic processGO:00098892500.050
carbohydrate biosynthetic processGO:001605110.050
actomyosin structure organizationGO:0031032530.049
cellular carbohydrate metabolic processGO:004426240.048
macromolecular complex assemblyGO:0065003350.048
establishment of localizationGO:00512342440.048
regulation of growthGO:0040008420.047
growthGO:00400071740.044
cell cell signalingGO:0007267520.044
myofibril assemblyGO:0030239480.044
regulation of biological qualityGO:00650082630.042
embryonic organ morphogenesisGO:00485622740.042
negative regulation of macromolecule metabolic processGO:0010605760.041
actin cytoskeleton organizationGO:0030036630.041
striated muscle tissue developmentGO:00147061100.040
programmed cell deathGO:00125011190.039
amine metabolic processGO:000930820.039
Worm
cellular macromolecule metabolic processGO:00442603910.038
regulation of macromolecule biosynthetic processGO:00105562250.038
branched chain amino acid metabolic processGO:000908110.038
axonogenesisGO:00074091520.038
cellular amide metabolic processGO:004360340.037
negative regulation of nitrogen compound metabolic processGO:0051172590.037
negative regulation of cellular processGO:00485232830.037
neuron projection morphogenesisGO:00488121610.036
cellular nitrogen compound metabolic processGO:00346412900.036
Zebrafish Worm
positive regulation of transportGO:005105020.036
regulation of cell deathGO:00109411030.035
regulation of extrinsic apoptotic signaling pathwayGO:200123630.035
organic cyclic compound metabolic processGO:19013603010.035
Zebrafish Worm
cell projection morphogenesisGO:00488582440.035
regulation of rna metabolic processGO:00512522240.034
polyol metabolic processGO:001975110.033
axon developmentGO:00615641660.033
ion transmembrane transportGO:0034220910.033
protein localization to plasma membraneGO:007265910.032
response to glucoseGO:000974930.032
chemosensory behaviorGO:000763510.031
organonitrogen compound metabolic processGO:1901564740.031
Zebrafish Worm
regulation of axonogenesisGO:0050770320.031
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.031
regulation of anatomical structure morphogenesisGO:00226031300.030
regulation of developmental growthGO:0048638380.030
neuron developmentGO:00486662620.030
ion transportGO:00068111140.029
cellular response to chemical stimulusGO:00708871570.029
response to hexoseGO:000974630.029
regulation of programmed cell deathGO:00430671010.029
central nervous system developmentGO:00074173870.029
Zebrafish
organic cyclic compound biosynthetic processGO:19013622230.029
Zebrafish Worm
transcription from rna polymerase ii promoterGO:0006366800.029
organelle organizationGO:00069962270.028
positive regulation of catabolic processGO:000989640.028
regulation of cell developmentGO:00602841000.028
regulation of synaptic plasticityGO:004816710.028
autophagyGO:000691440.027
monocarboxylic acid metabolic processGO:0032787170.027
cellular response to organic cyclic compoundGO:0071407380.026
aromatic compound biosynthetic processGO:00194382170.026
Zebrafish Worm
cellular lipid metabolic processGO:0044255360.026
protein homooligomerizationGO:005126030.026
regulation of localizationGO:00328791040.025
response to alkaloidGO:004327920.025
regulation of multicellular organismal developmentGO:20000262230.025
regulation of insulin like growth factor receptor signaling pathwayGO:004356710.025
brain developmentGO:00074202930.025
negative regulation of nucleobase containing compound metabolic processGO:0045934590.025
response to carbohydrateGO:000974330.024
cellular macromolecular complex assemblyGO:0034622240.024
gtp metabolic processGO:004603940.024
positive regulation of secretionGO:005104710.024
response to external stimulusGO:00096052640.024
cell morphogenesisGO:00009022890.024
regulation of gene expressionGO:00104682650.024
rna metabolic processGO:00160702190.023
regulation of cellular carbohydrate metabolic processGO:001067540.023
positive regulation of cellular carbohydrate metabolic processGO:001067610.023
cell morphogenesis involved in differentiationGO:00009041950.023
response to abiotic stimulusGO:00096281220.023
cell surface receptor signaling pathwayGO:00071663250.022
establishment of blood brain barrierGO:006085620.022
cellular response to endogenous stimulusGO:0071495680.022
positive regulation of cellular catabolic processGO:003133130.022
negative regulation of gene expressionGO:0010629650.022
lipid metabolic processGO:0006629520.022
cell part morphogenesisGO:00329902460.021
lipid oxidationGO:003444010.021
lipid catabolic processGO:001604240.021
organic substance transportGO:0071702580.021
synaptic growth at neuromuscular junctionGO:005112420.021
rna biosynthetic processGO:00327741810.021
immune system developmentGO:00025201910.020
ear developmentGO:00435831270.020
response to drugGO:004249330.020
regulation of signal transductionGO:00099662250.020
blood coagulationGO:0007596120.020
synaptic transmission cholinergicGO:000727140.020
sensory organ developmentGO:00074233930.020
regulation of cellular amine metabolic processGO:003323800.019
localization of cellGO:00516742440.019
protein complex biogenesisGO:0070271300.019
response to organic cyclic compoundGO:0014070510.019
positive regulation of developmental processGO:0051094500.019
cellular protein metabolic processGO:00442671290.018
small molecule catabolic processGO:004428230.018
Worm
cardiocyte differentiationGO:0035051440.018
pancreas developmentGO:0031016840.018
intracellular transportGO:0046907320.018
regulation of gtpase activityGO:004308720.018
protein complex assemblyGO:0006461300.018
regulation of nucleotide catabolic processGO:003081120.018
gland developmentGO:00487321430.018
vesicle mediated transportGO:0016192220.018
regulation of cell shapeGO:000836010.017
taxisGO:00423301090.017
blood vessel developmentGO:00015682460.017
regulation of carbohydrate metabolic processGO:000610940.017
myosin filament assemblyGO:003103460.017
tissue regenerationGO:0042246740.017
regulation of transcription dna templatedGO:00063552130.017
response to corticosteroidGO:003196010.016
positive regulation of cellular metabolic processGO:0031325940.016
female sex differentiationGO:004666040.016
oxidation reduction processGO:0055114410.016
Zebrafish Mouse Worm
trabecula formationGO:006034320.016
establishment of protein localization to organelleGO:007259440.016
regulation of protein transportGO:005122330.016
cellular amino acid biosynthetic processGO:000865220.016
Worm
vitamin a metabolic processGO:000677610.016
guanosine containing compound metabolic processGO:190106840.016
renal absorptionGO:007029310.016
mononuclear cell proliferationGO:003294310.016
regulation of carbohydrate biosynthetic processGO:004325510.016
tube morphogenesisGO:00352393490.016
response to transition metal nanoparticleGO:1990267280.015
camera type eye developmentGO:00430102220.015
positive regulation of carbohydrate metabolic processGO:004591310.015
nucleocytoplasmic transportGO:000691340.015
nuclear importGO:005117030.015
protein complex subunit organizationGO:0071822460.015
catechol containing compound metabolic processGO:000971220.015
Zebrafish
gtp catabolic processGO:000618420.015
cellular component movementGO:00069283350.015
nucleobase containing compound biosynthetic processGO:00346542050.015
small molecule biosynthetic processGO:0044283160.015
Worm
intracellular signal transductionGO:0035556850.015
macromolecule localizationGO:0033036540.015
leukocyte proliferationGO:007066110.014
regulation of reproductive processGO:200024140.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
response to monosaccharideGO:003428430.014
regulation of cell activationGO:005086510.014
positive regulation of secretion by cellGO:190353210.014
regulation of neural precursor cell proliferationGO:200017730.014
digestive tract morphogenesisGO:00485462310.014
pigmentationGO:0043473850.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
monovalent inorganic cation transportGO:0015672420.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
establishment of protein localization to plasma membraneGO:009000210.013
erk1 and erk2 cascadeGO:007037140.013
positive regulation of erk1 and erk2 cascadeGO:007037420.013
regulation of nervous system developmentGO:0051960900.013
skeletal system morphogenesisGO:00487051020.013
negative regulation of cell deathGO:0060548600.013
regulation of cellular ketone metabolic processGO:001056570.013
hormone biosynthetic processGO:004244630.013
regulation of synapse assemblyGO:005196330.013
epithelial cell migrationGO:0010631250.013
phagocytosisGO:000690930.013
positive regulation of gtp catabolic processGO:003312610.013
epithelial cell differentiationGO:00308551160.013
regulation of cellular amino acid metabolic processGO:000652100.013
negative regulation of signal transductionGO:0009968940.013
positive regulation of cell activationGO:005086710.013
striated muscle myosin thick filament assemblyGO:007168860.013
energy reserve metabolic processGO:000611220.013
generation of neuronsGO:00486993850.013
Zebrafish
organic hydroxy compound transportGO:0015850140.013
cell proliferationGO:0008283800.012
glucose homeostasisGO:004259310.012
regulation of establishment of protein localizationGO:007020140.012
glycerolipid biosynthetic processGO:004501710.012
transmembrane transportGO:00550851200.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
phosphorus metabolic processGO:00067931090.012
lymphocyte proliferationGO:004665110.012
membrane invaginationGO:001032410.012
positive regulation of multicellular organismal processGO:0051240520.012
intracellular receptor signaling pathwayGO:0030522300.012
cellular response to hormone stimulusGO:0032870390.012
endosomal transportGO:001619720.012
carbohydrate homeostasisGO:003350010.012
protein import into nucleusGO:000660630.012
system processGO:00030081850.012
digestive tract mesoderm developmentGO:000750210.012
neuroblast proliferationGO:000740520.012
vestibular receptor cell differentiationGO:006011430.012
digestive system developmentGO:00551232890.012
embryonic hemopoiesisGO:0035162530.012
multicellular organismal signalingGO:0035637220.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.011
negative regulation of developmental processGO:0051093650.011
protein importGO:001703830.011
neuron projection developmentGO:00311751800.011
regulation of autophagyGO:001050630.011
macromolecule modificationGO:00434121110.011
regulation of purine nucleotide catabolic processGO:003312120.011
cell migrationGO:00164772370.011
fatty acid transportGO:001590810.011
negative regulation of signalingGO:0023057960.011
cellular response to oxygen containing compoundGO:1901701200.011
negative regulation of synapse assemblyGO:005196420.011
cellular protein complex assemblyGO:0043623190.011
vitamin a biosynthetic processGO:003523810.011
negative regulation of cellular metabolic processGO:0031324770.011
cellular aldehyde metabolic processGO:000608140.011
sulfur compound metabolic processGO:0006790130.011
negative regulation of protein phosphorylationGO:000193340.011
neurotransmitter secretionGO:000726920.011
negative regulation of dna metabolic processGO:005105340.011
guanosine containing compound catabolic processGO:190106920.011
mrna 3 end processingGO:003112420.011
protein localization to nucleusGO:003450430.011
regulation of hormone levelsGO:0010817210.011
response to oxygen containing compoundGO:1901700550.011
chemotaxisGO:00069351040.011
taurine metabolic processGO:001953010.011
trabecula morphogenesisGO:006138320.010
regulation of synaptic growth at neuromuscular junctionGO:000858210.010
s adenosylmethionine metabolic processGO:004650010.010
regulation of neurogenesisGO:0050767870.010
response to glucocorticoidGO:005138410.010
cell matrix adhesionGO:000716040.010
negative chemotaxisGO:005091910.010
cardiac muscle tissue developmentGO:0048738480.010
single organism nuclear importGO:190259330.010
negative regulation of cell communicationGO:0010648960.010

pah disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.018
inherited metabolic disorderDOID:65500.018
amino acid metabolic disorderDOID:925200.018
musculoskeletal system diseaseDOID:1700.013
bone diseaseDOID:008000100.013
connective tissue diseaseDOID:6500.013
disease of anatomical entityDOID:700.013