Danio rerio

52 known processes

piwil1

piwi-like 1 (Drosophila)

(Aliases: ziwi)

piwil1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pole plasm assemblyGO:000731540.999
Fly
single organism reproductive processGO:0044702400.988
meiosis iiGO:000713510.976
female gamete generationGO:0007292140.971
Fly
gamete generationGO:0007276330.967
meiotic cell cycle processGO:190304630.965
meiotic nuclear divisionGO:000712640.963
Zebrafish
multicellular organismal reproductive processGO:0048609350.947
oocyte developmentGO:0048599140.935
Fly
reproductionGO:0000003400.913
oocyte differentiationGO:0009994140.908
Fly
negative regulation of dna recombinationGO:004591020.904
Fly
anterior posterior pattern specificationGO:00099521520.900
Fly
nucleic acid metabolic processGO:00903042440.898
sexual reproductionGO:0019953360.870
oocyte axis specificationGO:000730950.857
Fly
oogenesisGO:0048477140.835
Fly
response to chemicalGO:00422213200.832
Worm
multi organism reproductive processGO:0044703360.820
multi organism processGO:00517041340.789
generation of neuronsGO:00486993850.788
cellular process involved in reproduction in multicellular organismGO:0022412280.783
oocyte anterior posterior axis specificationGO:000731440.763
Fly
male meiosisGO:000714020.757
oocyte constructionGO:000730850.755
Fly
developmental process involved in reproductionGO:0003006270.745
meiotic chromosome segregationGO:004513230.742
embryonic axis specificationGO:0000578120.689
Fly
nucleobase containing compound metabolic processGO:00061392740.684
heterocycle metabolic processGO:00464832900.681
reproductive processGO:0022414400.673
negative regulation of gene expressionGO:0010629650.657
multicellular organism reproductionGO:0032504350.655
regionalizationGO:00030022740.620
Fly
organic cyclic compound metabolic processGO:19013603010.600
chromosome organization involved in meiosisGO:007019210.600
regulation of primary metabolic processGO:00800903110.595
Fly
cellular component assemblyGO:00226071700.575
Zebrafish Fly
germ cell developmentGO:0007281220.570
maternal determination of anterior posterior axis embryoGO:000835840.568
Fly
meiosis iGO:000712710.559
negative regulation of cellular metabolic processGO:0031324770.550
Fly
regulation of gene expressionGO:00104682650.548
gene expressionGO:00104672520.541
immune system processGO:00023762410.538
Fly
regulation of cellular metabolic processGO:00313233200.529
Fly
anterior posterior axis specification embryoGO:000859550.512
Fly
regulation of multicellular organismal processGO:00512392770.486
Fly
cell cycleGO:0007049930.461
Zebrafish Fly
axis specificationGO:0009798430.457
Fly
organelle fissionGO:0048285230.434
Zebrafish Fly
macromolecule biosynthetic processGO:00090592270.431
Fly
spermatogenesisGO:000728370.424
Mouse Fly
locomotionGO:00400113130.422
chromosome segregationGO:0007059120.403
Fly
cell cycle processGO:0022402530.386
Fly
regulation of meiotic cell cycleGO:005144510.385
positive regulation of cell cycleGO:004578730.383
negative regulation of feeding behaviorGO:200025220.379
regulation of multicellular organismal developmentGO:20000262230.379
Fly
nuclear divisionGO:0000280230.372
Zebrafish Fly
apoptotic processGO:00069151160.360
negative regulation of biological processGO:00485193040.356
response to organic substanceGO:00100331530.345
Worm
regulation of cell developmentGO:00602841000.322
Fly
segmentationGO:0035282970.298
Fly
regulation of macromolecule biosynthetic processGO:00105562250.296
Fly
cell projection organizationGO:00300302840.291
somitogenesisGO:0001756870.285
nitrogen compound metabolic processGO:00068073190.276
sister chromatid cohesionGO:000706220.276
programmed cell deathGO:00125011190.274
meiotic cell cycleGO:005132150.274
Zebrafish
regulation of biological qualityGO:00650082630.273
localization of cellGO:00516742440.271
oocyte growthGO:000155510.249
regulation of developmental processGO:00507932470.245
Zebrafish Fly
female meiotic divisionGO:000714320.238
protein metabolic processGO:00195381830.231
establishment of localizationGO:00512342440.229
cellular macromolecule metabolic processGO:00442603910.224
embryo development ending in birth or egg hatchingGO:00097922710.222
Worm
negative regulation of cell deathGO:0060548600.217
androgen metabolic processGO:000820920.217
rna biosynthetic processGO:00327741810.213
Fly
cell motilityGO:00488702440.212
development of primary female sexual characteristicsGO:004654540.212
response to external stimulusGO:00096052640.210
Fly
female sex differentiationGO:004666040.205
cellular nitrogen compound metabolic processGO:00346412900.203
regulation of cell deathGO:00109411030.201
male gamete generationGO:004823270.197
Mouse Fly
female meiosis chromosome segregationGO:001632110.190
regulation of cell maturationGO:190342910.187
Fly
single organism metabolic processGO:00447102170.181
Worm Fly
rna stabilizationGO:004348940.180
stem cell divisionGO:001714510.179
Fly
response to amino acidGO:004320020.176
single organism transportGO:00447652060.175
cellular biosynthetic processGO:00442492860.175
Fly
negative regulation of macromolecule metabolic processGO:0010605760.175
biosynthetic processGO:00090582940.172
Fly
neuron developmentGO:00486662620.171
stem cell maintenanceGO:001982740.168
Zebrafish Fly
oocyte maturationGO:000155640.165
Fly
regulation of cellular protein metabolic processGO:0032268520.165
positive regulation of protein metabolic processGO:0051247230.160
regulation of metabolic processGO:00192223590.156
regulation of mrna processingGO:005068430.154
Fly
response to stressGO:00069502630.151
Worm Fly
smad protein complex assemblyGO:000718310.151
Zebrafish
positive regulation of cellular processGO:00485222010.148
Fly
positive regulation of translationGO:004572710.147
developmental growthGO:00485891660.144
regulation of protein complex assemblyGO:004325430.144
Zebrafish
cellular response to organic substanceGO:00713101050.140
Worm
cellular component movementGO:00069283350.136
embryonic organ morphogenesisGO:00485622740.132
cellular macromolecule biosynthetic processGO:00346452240.126
Fly
regulation of mrna catabolic processGO:006101330.118
Fly
regulation of response to stimulusGO:00485832690.116
Zebrafish Fly
regulation of cellular component movementGO:0051270550.116
aromatic compound biosynthetic processGO:00194382170.115
Fly
deathGO:00162651210.113
regulation of cellular biosynthetic processGO:00313262450.112
Fly
regulation of localizationGO:00328791040.112
Fly
positive regulation of macromolecule biosynthetic processGO:0010557590.110
cellular hormone metabolic processGO:0034754190.107
stem cell developmentGO:0048864820.107
Zebrafish Fly
cellular response to chemical stimulusGO:00708871570.099
Worm
neuron differentiationGO:00301823530.098
cell migrationGO:00164772370.097
response to organic cyclic compoundGO:0014070510.095
Worm
mitotic cell cycleGO:0000278640.091
Fly
negative regulation of programmed cell deathGO:0043069580.090
regulation of immune system processGO:0002682340.090
Fly
response to glucocorticoidGO:005138410.089
negative regulation of cellular processGO:00485232830.087
Zebrafish Fly
cytoplasm organizationGO:000702840.086
Fly
germ cell migrationGO:000835480.085
regulation of smad protein complex assemblyGO:001099010.085
Zebrafish
single organism localizationGO:19025782250.084
Fly
nuclear transcribed mrna catabolic processGO:000095640.081
Fly
organelle organizationGO:00069962270.080
Zebrafish Fly
regulation of stem cell proliferationGO:007209120.079
regulation of apoptotic processGO:0042981980.079
positive regulation of stem cell proliferationGO:200064810.077
regulation of nitrogen compound metabolic processGO:00511712510.076
Fly
regulation of rna biosynthetic processGO:20011412130.075
Fly
cell deathGO:00082191210.075
mitotic cell cycle processGO:1903047480.074
Fly
regulation of alternative mrna splicing via spliceosomeGO:000038110.074
somite developmentGO:0061053960.072
positive regulation of cellular metabolic processGO:0031325940.071
Fly
regulation of reproductive processGO:200024140.071
Fly
synapsisGO:000712910.071
cellular aromatic compound metabolic processGO:00067252950.070
axon guidanceGO:0007411860.070
neuron projection morphogenesisGO:00488121610.068
organic substance biosynthetic processGO:19015762890.068
Fly
regulation of locomotionGO:0040012550.067
developmental maturationGO:0021700340.067
Fly
regulation of hormone levelsGO:0010817210.066
cellular protein modification processGO:00064641000.065
cell part morphogenesisGO:00329902460.063
immune responseGO:0006955280.063
Fly
spermatid developmentGO:000728620.063
Mouse
estrogen metabolic processGO:000821020.063
positive regulation of neural precursor cell proliferationGO:200017910.062
positive regulation of cell divisionGO:005178120.061
regulation of innate immune responseGO:0045088110.060
Fly
transportGO:00068102200.060
female gonad developmentGO:000858540.060
negative regulation of reproductive processGO:200024230.059
positive regulation of map kinase activityGO:004340630.059
reciprocal dna recombinationGO:003582510.058
sister chromatid segregationGO:000081960.058
Fly
agingGO:000756820.058
regulation of oocyte developmentGO:006028130.057
Fly
response to nitrogen compoundGO:1901698190.057
Worm
regulation of protein metabolic processGO:0051246560.057
notochord developmentGO:0030903540.056
regenerationGO:0031099910.056
negative regulation of apoptotic processGO:0043066550.055
skeletal system developmentGO:00015011810.054
positive regulation of response to stimulusGO:0048584800.054
Fly
stem cell proliferationGO:007208940.053
female germ line stem cell maintenanceGO:003609910.052
cell morphogenesis involved in differentiationGO:00009041950.052
dicarboxylic acid metabolic processGO:004364810.052
cell morphogenesis involved in neuron differentiationGO:00486671630.052
tripartite regional subdivisionGO:000735150.051
Fly
phosphorus metabolic processGO:00067931090.051
regulation of cell cycleGO:0051726520.050
response to oxygen containing compoundGO:1901700550.050
blood vessel developmentGO:00015682460.050
system processGO:00030081850.050
methylationGO:0032259220.049
dna templated transcription initiationGO:000635210.048
regulation of cell communicationGO:00106462320.048
Zebrafish
regulation of hormone secretionGO:004688320.048
alternative mrna splicing via spliceosomeGO:000038010.048
cellular protein metabolic processGO:00442671290.048
camera type eye developmentGO:00430102220.048
ovulation cycle processGO:002260220.047
negative regulation of metabolic processGO:0009892860.044
hormone metabolic processGO:0042445190.044
tissue remodelingGO:004877140.044
positive regulation of transportGO:005105020.043
regulation of rna metabolic processGO:00512522240.043
Fly
defense responseGO:0006952470.043
Worm Fly
germ line stem cell divisionGO:004207810.043
Fly
regulation of cellular macromolecule biosynthetic processGO:20001122220.042
Fly
larval developmentGO:000216420.042
anterior posterior axis specificationGO:0009948200.042
Fly
positive regulation of developmental processGO:0051094500.041
regulation of neurogenesisGO:0050767870.041
rna metabolic processGO:00160702190.040
protein complex subunit organizationGO:0071822460.040
Zebrafish
regulation of biosynthetic processGO:00098892500.039
Fly
epithelial cell differentiationGO:00308551160.039
Fly
protein phosphorylationGO:0006468470.039
specification of symmetryGO:00097992040.038
macromolecule modificationGO:00434121110.038
positive regulation of cellular protein metabolic processGO:0032270220.037
xenobiotic metabolic processGO:000680540.037
mitotic nuclear divisionGO:0007067180.036
Fly
maintenance of locationGO:005123540.036
organic cyclic compound biosynthetic processGO:19013622230.036
Fly
blood vessel morphogenesisGO:00485142160.036
cellular component morphogenesisGO:00329893360.035
Fly
regulation of macromolecule metabolic processGO:00602553170.035
mesoderm developmentGO:0007498880.035
androgen biosynthetic processGO:000670210.035
endodermal cell fate determinationGO:000749320.033
establishment of localization in cellGO:0051649770.033
positive regulation of cellular biosynthetic processGO:0031328680.033
reproductive structure developmentGO:004860850.033
regulation of cell motilityGO:2000145460.033
female meiosis iiGO:000714710.032
dna recombinationGO:000631050.032
Fly
spermatid differentiationGO:004851520.030
Mouse
cellular lipid metabolic processGO:0044255360.030
regulation of catalytic activityGO:0050790550.030
response to biotic stimulusGO:0009607970.030
Fly
tissue regenerationGO:0042246740.029
positive regulation of mrna metabolic processGO:190331320.029
Fly
positive regulation of rna metabolic processGO:0051254590.029
Fly
mrna metabolic processGO:0016071200.028
Fly
negative regulation of nucleic acid templated transcriptionGO:1903507450.028
Fly
eye developmentGO:00016542770.028
cell morphogenesisGO:00009022890.028
rhythmic processGO:0048511210.028
bone remodelingGO:004684920.028
stem cell differentiationGO:00488631170.028
Zebrafish Fly
cell maturationGO:0048469230.028
Fly
chromosome organizationGO:0051276310.028
Fly
cell fate commitmentGO:0045165990.027
neuron projection guidanceGO:0097485860.027
cell projection morphogenesisGO:00488582440.027
rna localizationGO:000640340.027
Fly
regulation of signalingGO:00230512350.027
Zebrafish
negative regulation of transcription dna templatedGO:0045892450.027
Fly
response to nutrientGO:000758430.027
positive regulation of canonical wnt signaling pathwayGO:009026340.026
cellular response to lipidGO:0071396390.026
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.026
Zebrafish
defense response to other organismGO:0098542330.026
Fly
purine nucleoside monophosphate catabolic processGO:000912840.025
regulation of signal transductionGO:00099662250.025
Zebrafish
response to external biotic stimulusGO:0043207970.024
Fly
determination of left right symmetryGO:00073681790.024
cell fate commitment involved in formation of primary germ layerGO:0060795260.024
dna biosynthetic processGO:007189730.024
regulation of cytokine productionGO:000181730.024
reciprocal meiotic recombinationGO:000713110.024
proepicardium developmentGO:000334240.023
response to alkaloidGO:004327920.023
nucleic acid templated transcriptionGO:00976591810.023
Fly
negative regulation of rna metabolic processGO:0051253480.023
Fly
epithelial cell developmentGO:0002064420.023
Fly
dorsal ventral pattern formationGO:00099531250.022
neuron projection developmentGO:00311751800.022
angiogenesisGO:00015251580.022
meiotic spindle organizationGO:000021210.022
response to monosaccharideGO:003428430.022
phosphorylationGO:0016310690.022
negative regulation of response to stimulusGO:00485851040.021
Zebrafish
axonogenesisGO:00074091520.021
regulation of programmed cell deathGO:00430671010.021
spemann organizer formationGO:0060061100.021
mrna stabilizationGO:004825540.021
growthGO:00400071740.021
regulation of molecular functionGO:0065009700.021
regulation of endodermal cell fate specificationGO:0042663150.021
dna metabolic processGO:0006259270.021
Fly
cell proliferationGO:0008283800.021
cellular amine metabolic processGO:004410620.020
response to corticosteroidGO:003196010.020
wound healingGO:0042060900.020
regulation of phosphorus metabolic processGO:0051174430.020
cellular response to antibioticGO:007123610.020
rna processingGO:0006396250.020
Worm Fly
regulation of translational initiationGO:000644610.020
brain developmentGO:00074202930.020
response to vitaminGO:003327330.020
determination of bilateral symmetryGO:00098552040.020
cellular response to stressGO:0033554620.020
positive regulation of lipid metabolic processGO:004583410.020
sensory organ developmentGO:00074233930.020
negative regulation of cellular biosynthetic processGO:0031327550.019
Fly
multicellular organism growthGO:003526440.019
negative regulation of signal transductionGO:0009968940.019
Zebrafish
liver developmentGO:0001889960.019
ovarian follicle developmentGO:000154120.019
cation transmembrane transportGO:0098655650.019
positive regulation of molecular functionGO:0044093330.019
posttranscriptional regulation of gene expressionGO:0010608140.019
Worm Fly
skeletal muscle organ developmentGO:0060538780.019
organic cyclic compound catabolic processGO:1901361150.019
Fly
protein maturationGO:0051604120.019
positive regulation of cellular component biogenesisGO:004408930.018
development of primary sexual characteristicsGO:004513750.018
enzyme linked receptor protein signaling pathwayGO:00071671060.018
Zebrafish
cell cycle g1 s phase transitionGO:004484310.018
regulation of gene silencing by rnaGO:006096610.018
positive regulation of biological processGO:00485182530.018
Zebrafish Fly
regulation of erk1 and erk2 cascadeGO:007037240.018
microtubule cytoskeleton organizationGO:0000226330.018
blastoderm segmentationGO:000735060.018
Fly
regulation of translationGO:000641730.018
regulation of immune responseGO:0050776140.018
Fly
aromatic compound catabolic processGO:0019439150.017
Fly
photoreceptor cell differentiationGO:0046530550.017
striated muscle tissue developmentGO:00147061100.017
positive regulation of cell proliferationGO:0008284150.017
positive regulation of signalingGO:0023056560.017
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.017
Fly
macromolecule localizationGO:0033036540.017
Fly
ncrna metabolic processGO:0034660120.017
septum transversum developmentGO:000334340.017
rna catabolic processGO:000640170.017
Fly
muscle tissue developmentGO:00605371100.017
digestive system developmentGO:00551232890.017
phagocytosisGO:000690930.017
cellular nitrogen compound biosynthetic processGO:00442712180.016
Fly
response to xenobiotic stimulusGO:0009410450.016
negative regulation of cell differentiationGO:0045596460.016
Zebrafish Fly
cognitionGO:005089010.016
organ growthGO:0035265120.016
serotonin metabolic processGO:004242810.016
transcription dna templatedGO:00063511810.016
Fly
cell cycle phase transitionGO:004477090.016
axon developmentGO:00615641660.016
ovulation cycleGO:004269820.016
establishment of chromosome localizationGO:005130320.016
digestive tract developmentGO:00485652650.016
protein modification processGO:00362111000.016
ion transmembrane transportGO:0034220910.015
regulation of phosphorylationGO:0042325260.015
regulation of cardiac muscle tissue developmentGO:005502410.015
spindle assemblyGO:005122520.015
embryonic pattern specificationGO:0009880440.015
Fly
regulation of transferase activityGO:0051338160.015
heart loopingGO:0001947940.015
connective tissue developmentGO:0061448990.015
skeletal muscle tissue developmentGO:0007519670.015
negative regulation of signalingGO:0023057960.015
Zebrafish
central nervous system developmentGO:00074173870.015
chromosome localizationGO:005000020.015
male meiosis iGO:000714110.015
cellular response to hypoxiaGO:007145610.015
cell growthGO:0016049570.015
camera type eye morphogenesisGO:00485931080.015
response to lipidGO:0033993600.014
odontogenesis of dentin containing toothGO:004247510.014
membrane lipid biosynthetic processGO:004646720.014
fin developmentGO:0033333770.014
single organism biosynthetic processGO:0044711710.014
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.014
response to ketoneGO:190165410.014
nephric duct developmentGO:0072176130.014
sphingolipid biosynthetic processGO:003014820.014
neuromast developmentGO:0048884460.014
dorsal ventral axis specificationGO:0009950140.014
negative regulation of rna biosynthetic processGO:1902679450.013
Fly
positive regulation of cytoskeleton organizationGO:005149530.013
amine metabolic processGO:000930820.013
heterocycle biosynthetic processGO:00181302150.013
Fly
positive regulation of phosphorus metabolic processGO:0010562210.013
signal transductionGO:00071654550.013
Zebrafish
cellular response to extracellular stimulusGO:003166820.013
metal ion transportGO:0030001580.013
microtubule based processGO:0007017600.013
telencephalon developmentGO:0021537140.013
regulation of receptor internalizationGO:000209020.013
phosphate containing compound metabolic processGO:00067961080.012
sex determinationGO:000753010.012
cellular response to fibroblast growth factor stimulusGO:0044344220.012
lipid metabolic processGO:0006629520.012
cellular component biogenesisGO:00440851780.012
Zebrafish Fly
cellular response to oxygen levelsGO:007145310.012
phagocytosis engulfmentGO:000691110.012
mesenchyme developmentGO:00604851270.012
response to carbohydrateGO:000974330.012
negative regulation of gene silencingGO:006096910.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
Fly
urogenital system developmentGO:0001655970.012
fin regenerationGO:0031101510.012
negative regulation of behaviorGO:004852160.012
positive regulation of catabolic processGO:000989640.012
Fly
chromatin modificationGO:0016568210.012
phosphatidylinositol mediated signalingGO:004801520.012
regulation of kinase activityGO:0043549150.012
mitotic sister chromatid segregationGO:000007060.012
Fly
translationGO:000641250.012
catabolic processGO:0009056320.012
Fly
response to antibioticGO:004667710.012
cation homeostasisGO:0055080330.011
gene silencingGO:001645840.011
muscle fiber developmentGO:0048747520.011
appendage developmentGO:0048736800.011
ribonucleoside monophosphate catabolic processGO:000915840.011
organelle localizationGO:0051640490.011
endothelial cell differentiationGO:0045446200.011
membrane invaginationGO:001032410.011
cellular response to decreased oxygen levelsGO:003629410.011
cellular response to dna damage stimulusGO:0006974240.011
negative regulation of nucleobase containing compound metabolic processGO:0045934590.011
Fly
regulation of posttranscriptional gene silencingGO:006014710.011
appendage morphogenesisGO:0035107560.011
regulation of peptidase activityGO:0052547230.010
regulation of transcription from rna polymerase ii promoterGO:00063571140.010
response to hypoxiaGO:0001666250.010
regulation of vasculature developmentGO:1901342330.010
inositol lipid mediated signalingGO:004801720.010
regulation of cellular amine metabolic processGO:003323800.010
macromolecule methylationGO:0043414190.010
negative regulation of multicellular organismal processGO:0051241690.010
regulation of protein catabolic processGO:004217610.010
negative regulation of hormone secretionGO:004688820.010

piwil1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
endocrine system diseaseDOID:2800.113
disease of anatomical entityDOID:700.113
immune system diseaseDOID:291400.062
hematopoietic system diseaseDOID:7400.039
bone marrow diseaseDOID:496100.039
fanconi s anemiaDOID:1363600.029
congenital hypoplastic anemiaDOID:134200.029
anemiaDOID:235500.029
aplastic anemiaDOID:1244900.029
bone development diseaseDOID:008000600.021
musculoskeletal system diseaseDOID:1700.021
connective tissue diseaseDOID:6500.021
bone diseaseDOID:008000100.021
disease of metabolismDOID:001466700.015
lipid metabolism disorderDOID:314600.015
inherited metabolic disorderDOID:65500.015
reproductive system diseaseDOID:1500.014