Danio rerio

22 known processes

pold1

polymerase (DNA directed), delta 1, catalytic subunit

(Aliases: MGC152688,fla,zgc:152688,im:7139126)

pold1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:00097922710.852
Worm
meiotic cell cycle processGO:190304630.775
meiotic chromosome segregationGO:004513230.580
meiosis iGO:000712710.512
biosynthetic processGO:00090582940.506
locomotionGO:00400113130.487
skeletal system developmentGO:00015011810.445
cell cycle processGO:0022402530.435
single organism biosynthetic processGO:0044711710.382
cell cycleGO:0007049930.377
cellular biosynthetic processGO:00442492860.355
chordate embryonic developmentGO:00430092710.339
camera type eye developmentGO:00430102220.338
single organism organelle organizationGO:19025891990.317
larval developmentGO:000216420.314
Worm
retina development in camera type eyeGO:00600411460.313
mitotic dna integrity checkpointGO:004477440.295
nucleic acid metabolic processGO:00903042440.281
double strand break repairGO:000630230.267
meiotic nuclear divisionGO:000712640.262
heterocycle metabolic processGO:00464832900.257
chromosome organizationGO:0051276310.253
cellular protein catabolic processGO:004425740.246
cellular aromatic compound metabolic processGO:00067252950.241
organic substance biosynthetic processGO:19015762890.237
neuron differentiationGO:00301823530.233
mitotic cell cycleGO:0000278640.225
cell projection organizationGO:00300302840.217
dna metabolic processGO:0006259270.215
regulation of dna replicationGO:000627530.195
double strand break repair via homologous recombinationGO:000072410.185
connective tissue developmentGO:0061448990.183
cellular macromolecule metabolic processGO:00442603910.179
nitrogen compound metabolic processGO:00068073190.177
macromolecule biosynthetic processGO:00090592270.168
sensory organ developmentGO:00074233930.166
nucleobase containing compound metabolic processGO:00061392740.163
negative regulation of chromosome organizationGO:200125110.152
embryonic organ morphogenesisGO:00485622740.151
neuron developmentGO:00486662620.147
organonitrogen compound metabolic processGO:1901564740.146
retina layer formationGO:0010842240.144
aromatic compound biosynthetic processGO:00194382170.141
Human Yeast
negative regulation of histone methylationGO:003106110.141
regulation of protein catabolic processGO:004217610.139
eye developmentGO:00016542770.139
organic cyclic compound biosynthetic processGO:19013622230.139
Human Yeast
negative regulation of cell cycle processGO:001094890.134
negative regulation of cellular processGO:00485232830.133
cellular nitrogen compound metabolic processGO:00346412900.126
recombinational repairGO:000072510.119
male meiosisGO:000714020.116
sister chromatid cohesionGO:000706220.116
maintenance of locationGO:005123540.109
rna biosynthetic processGO:00327741810.106
regulation of transcription dna templatedGO:00063552130.106
response to stressGO:00069502630.105
Human Mouse
apoptotic processGO:00069151160.105
regulation of histone h3 k9 methylationGO:005157020.104
generation of neuronsGO:00486993850.104
microtubule cytoskeleton organization involved in mitosisGO:190285010.102
cell projection morphogenesisGO:00488582440.101
nucleobase containing compound biosynthetic processGO:00346542050.093
Human Yeast
cellular response to endogenous stimulusGO:0071495680.092
dna methylation on cytosineGO:003277630.092
regulation of meiotic cell cycleGO:005144510.091
embryonic cranial skeleton morphogenesisGO:0048701900.090
gene expressionGO:00104672520.090
pyrimidine containing compound metabolic processGO:007252730.089
cellular macromolecule biosynthetic processGO:00346452240.089
camera type eye morphogenesisGO:00485931080.086
positive regulation of catabolic processGO:000989640.085
response to organic substanceGO:00100331530.085
neural retina developmentGO:0003407490.084
organic acid metabolic processGO:0006082310.081
small molecule metabolic processGO:0044281770.080
digestive tract developmentGO:00485652650.080
regulation of cellular biosynthetic processGO:00313262450.079
negative regulation of nitrogen compound metabolic processGO:0051172590.079
cellular component movementGO:00069283350.079
negative regulation of nuclear divisionGO:005178430.077
ubiquitin dependent protein catabolic processGO:000651130.073
cellular response to chemical stimulusGO:00708871570.072
cell morphogenesisGO:00009022890.072
regulation of nucleic acid templated transcriptionGO:19035062130.071
cellular component morphogenesisGO:00329893360.070
organelle organizationGO:00069962270.070
microtubule based processGO:0007017600.069
mesenchymal cell differentiationGO:0048762870.068
regulation of nitrogen compound metabolic processGO:00511712510.067
reproductive processGO:0022414400.067
regulation of macromolecule metabolic processGO:00602553170.065
pharyngeal system developmentGO:0060037180.065
cell part morphogenesisGO:00329902460.065
positive regulation of histone modificationGO:003105810.064
chromosome organization involved in meiosisGO:007019210.064
macromolecular complex subunit organizationGO:0043933740.063
reciprocal meiotic recombinationGO:000713110.062
sex determinationGO:000753010.059
zymogen activationGO:003163830.058
negative regulation of cellular biosynthetic processGO:0031327550.058
retina morphogenesis in camera type eyeGO:0060042790.058
regulation of cell cycleGO:0051726520.058
negative regulation of metabolic processGO:0009892860.057
multicellular organism reproductionGO:0032504350.057
gland developmentGO:00487321430.056
positive regulation of chromatin modificationGO:190331010.056
pancreas developmentGO:0031016840.056
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.056
mitotic nuclear divisionGO:0007067180.056
cellular component biogenesisGO:00440851780.056
negative regulation of macromolecule metabolic processGO:0010605760.056
negative regulation of biosynthetic processGO:0009890550.054
negative regulation of mitotic cell cycleGO:0045930110.054
proteolysis involved in cellular protein catabolic processGO:005160330.054
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.051
negative regulation of cellular metabolic processGO:0031324770.051
embryonic skeletal system morphogenesisGO:0048704930.050
regulation of cellular metabolic processGO:00313233200.048
neuron projection morphogenesisGO:00488121610.048
multicellular organismal reproductive processGO:0048609350.046
cellular response to stressGO:0033554620.046
Human Mouse
modification dependent protein catabolic processGO:001994130.046
embryonic skeletal system developmentGO:0048706970.046
homeostatic processGO:00425921420.045
Human
carbohydrate derivative metabolic processGO:1901135610.044
cell motilityGO:00488702440.044
immune system processGO:00023762410.044
modification dependent macromolecule catabolic processGO:004363230.044
embryonic viscerocranium morphogenesisGO:0048703520.043
regulation of chromosome segregationGO:005198310.042
peptidyl serine modificationGO:001820920.042
protein complex subunit organizationGO:0071822460.042
negative regulation of mitotic cell cycle phase transitionGO:190199150.040
mitotic cell cycle processGO:1903047480.040
cellular component assemblyGO:00226071700.040
carboxylic acid metabolic processGO:0019752220.040
dna biosynthetic processGO:007189730.040
Human Yeast
negative regulation of biological processGO:00485193040.040
regulation of stem cell proliferationGO:007209120.039
negative regulation of cell divisionGO:005178240.039
tube morphogenesisGO:00352393490.038
cell migrationGO:00164772370.038
single organism metabolic processGO:00447102170.037
Human Mouse
transcription from rna polymerase ii promoterGO:0006366800.037
negative regulation of macromolecule biosynthetic processGO:0010558480.037
regulation of endopeptidase activityGO:0052548230.036
cell fate commitmentGO:0045165990.036
protein metabolic processGO:00195381830.035
ribonucleoside monophosphate catabolic processGO:000915840.035
nucleic acid phosphodiester bond hydrolysisGO:009030560.035
Yeast Mouse
covalent chromatin modificationGO:0016569200.034
cellular catabolic processGO:0044248270.034
Yeast
transcription dna templatedGO:00063511810.034
negative regulation of cell cycle phase transitionGO:190198850.034
photoreceptor cell differentiationGO:0046530550.034
dna damage checkpointGO:000007760.033
regulation of proteolysisGO:0030162240.033
regulation of gene expressionGO:00104682650.033
response to chemicalGO:00422213200.033
programmed cell deathGO:00125011190.033
meiosis iiGO:000713510.032
phosphate containing compound metabolic processGO:00067961080.032
peptidyl serine phosphorylationGO:001810510.032
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.032
b cell activationGO:004211320.032
nucleoside monophosphate catabolic processGO:000912540.032
deathGO:00162651210.031
neuron projection developmentGO:00311751800.031
proteasomal protein catabolic processGO:001049820.031
regulation of histone methylationGO:003106030.031
cartilage developmentGO:0051216960.031
multicellular organism growthGO:003526440.030
regulation of macromolecule biosynthetic processGO:00105562250.030
response to endogenous stimulusGO:0009719830.030
digestive system developmentGO:00551232890.030
regulation of cellular protein catabolic processGO:190336210.030
protein importGO:001703830.030
mitotic spindle organizationGO:000705250.030
organic cyclic compound metabolic processGO:19013603010.029
oxoacid metabolic processGO:0043436310.029
agingGO:000756820.029
rna metabolic processGO:00160702190.029
Yeast
peptidyl threonine phosphorylationGO:001810710.029
regulation of purine nucleotide catabolic processGO:003312120.028
dna catabolic processGO:000630810.028
Yeast
phosphorus metabolic processGO:00067931090.027
negative regulation of nucleic acid templated transcriptionGO:1903507450.027
chromatin organizationGO:0006325220.027
germ cell developmentGO:0007281220.027
regulation of nucleobase containing compound metabolic processGO:00192192500.027
regulation of nucleotide catabolic processGO:003081120.026
positive regulation of chromosome organizationGO:200125210.026
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.026
dna recombinationGO:000631050.026
hematopoietic or lymphoid organ developmentGO:00485341910.026
liver developmentGO:0001889960.026
exocrine pancreas developmentGO:0031017280.026
regulation of cellular ketone metabolic processGO:001056570.026
mesenchyme developmentGO:00604851270.026
macromolecule methylationGO:0043414190.026
eye photoreceptor cell differentiationGO:0001754450.026
negative regulation of transcription dna templatedGO:0045892450.026
cell cycle g2 m phase transitionGO:004483940.025
signal transductionGO:00071654550.025
reproductionGO:0000003400.025
camera type eye photoreceptor cell differentiationGO:0060219190.025
regulation of synapse organizationGO:005080730.025
guanosine containing compound metabolic processGO:190106840.025
cell morphogenesis involved in neuron differentiationGO:00486671630.025
thymus developmentGO:0048538100.025
regulation of biological qualityGO:00650082630.025
Human
negative regulation of catabolic processGO:000989530.025
negative regulation of dna metabolic processGO:005105340.024
purine nucleoside monophosphate catabolic processGO:000912840.024
developmental process involved in reproductionGO:0003006270.024
regulation of catalytic activityGO:0050790550.024
regionalizationGO:00030022740.024
cellular nitrogen compound biosynthetic processGO:00442712180.024
Human Yeast
positive regulation of metabolic processGO:00098931080.024
oocyte maturationGO:000155640.024
growthGO:00400071740.024
g1 s transition of mitotic cell cycleGO:000008210.024
regulation of biosynthetic processGO:00098892500.023
hatchingGO:003518840.023
Worm
muscle structure developmentGO:00610611960.023
cellular modified amino acid metabolic processGO:000657530.023
hepaticobiliary system developmentGO:0061008980.023
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.023
sexual reproductionGO:0019953360.023
heterocycle biosynthetic processGO:00181302150.023
Human Yeast
positive regulation of cellular catabolic processGO:003133130.022
mitotic metaphase plate congressionGO:000708010.022
regulation of peptidase activityGO:0052547230.022
negative regulation of cell cycleGO:0045786140.022
mitotic recombinationGO:000631220.022
methylationGO:0032259220.022
cell deathGO:00082191210.022
proteolysisGO:0006508380.022
chromosome segregationGO:0007059120.022
carbohydrate derivative biosynthetic processGO:1901137430.021
atp catabolic processGO:000620040.021
purine ribonucleoside monophosphate catabolic processGO:000916940.021
negative regulation of gene expressionGO:0010629650.021
nucleic acid templated transcriptionGO:00976591810.021
spindle assemblyGO:005122520.021
nuclear importGO:005117030.021
female meiotic divisionGO:000714320.020
cell morphogenesis involved in differentiationGO:00009041950.020
gtp metabolic processGO:004603940.020
sister chromatid segregationGO:000081960.020
dna alkylationGO:000630580.020
negative regulation of rna metabolic processGO:0051253480.020
blood vessel morphogenesisGO:00485142160.020
cellular amino acid metabolic processGO:000652070.019
positive regulation of nucleobase containing compound metabolic processGO:0045935690.019
axis specificationGO:0009798430.019
intracellular signal transductionGO:0035556850.019
phagocytosisGO:000690930.019
multi organism processGO:00517041340.019
angiogenesisGO:00015251580.019
lymphocyte proliferationGO:004665110.019
lateral inhibitionGO:004633110.019
negative regulation of nucleobase containing compound metabolic processGO:0045934590.019
protein localization to nucleusGO:003450430.019
cellular component assembly involved in morphogenesisGO:00109271070.019
nucleobase containing small molecule metabolic processGO:0055086320.019
extracellular structure organizationGO:0043062270.019
microtubule polymerizationGO:004678520.019
negative regulation of histone modificationGO:003105710.019
response to abiotic stimulusGO:00096281220.019
immunoglobulin productionGO:000237710.018
guanosine containing compound catabolic processGO:190106920.018
neuroblast fate determinationGO:000740010.018
regulation of metabolic processGO:00192223590.018
regulation of cell cycle phase transitionGO:190198780.018
b cell mediated immunityGO:001972430.017
cell proliferationGO:0008283800.017
catabolic processGO:0009056320.017
Yeast
reciprocal dna recombinationGO:003582510.017
positive regulation of molecular functionGO:0044093330.017
meiotic spindle organizationGO:000021210.017
gene silencingGO:001645840.017
spindle assembly involved in mitosisGO:009030710.017
cytoskeleton organizationGO:0007010960.017
positive regulation of nitrogen compound metabolic processGO:0051173690.017
negative regulation of cytoplasmic transportGO:190365020.017
immunoglobulin mediated immune responseGO:001606430.016
regulation of rna biosynthetic processGO:20011412130.016
negative regulation of organelle organizationGO:001063940.016
ribonucleotide metabolic processGO:0009259270.016
developmental growth involved in morphogenesisGO:0060560860.016
vesicle mediated transportGO:0016192220.016
Worm
regulation of response to stimulusGO:00485832690.016
cellular response to organic substanceGO:00713101050.016
protein complex assemblyGO:0006461300.016
g2 m transition of mitotic cell cycleGO:000008640.016
establishment of protein localization to organelleGO:007259440.016
response to oxygen containing compoundGO:1901700550.016
female meiosis chromosome segregationGO:001632110.016
nerve developmentGO:0021675450.016
regulation of establishment of protein localizationGO:007020140.016
cellular amine metabolic processGO:004410620.016
regulation of chromatin organizationGO:190227550.016
single organism nuclear importGO:190259330.016
organic substance catabolic processGO:1901575280.016
Yeast
protein polymerizationGO:005125840.016
positive regulation of apoptotic processGO:0043065290.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
dna replicationGO:000626060.015
common bile duct developmentGO:0061009130.015
macromolecular complex assemblyGO:0065003350.015
cell migration involved in gastrulationGO:0042074790.015
purine nucleotide metabolic processGO:0006163270.015
lens development in camera type eyeGO:0002088220.015
cytokinesisGO:000091030.015
meiotic cell cycleGO:005132150.015
heterocycle catabolic processGO:0046700150.015
Yeast
regulation of apoptotic processGO:0042981980.015
regulation of anatomical structure morphogenesisGO:00226031300.015
mitotic cell cycle phase transitionGO:004477290.015
response to antibioticGO:004667710.015
organonitrogen compound biosynthetic processGO:1901566470.015
regulation of mitotic cell cycleGO:0007346250.015
regulation of nucleocytoplasmic transportGO:004682220.015
stem cell differentiationGO:00488631170.014
dna methylation or demethylationGO:004472880.014
negative regulation of rna biosynthetic processGO:1902679450.014
regulation of dendrite developmentGO:005077330.014
regulation of transcription from rna polymerase ii promoterGO:00063571140.014
regulation of cellular protein metabolic processGO:0032268520.014
response to uvGO:000941130.014
autonomic nervous system developmentGO:0048483190.014
regulation of neural precursor cell proliferationGO:200017730.014
response to woundingGO:00096111160.014
somatic cell dna recombinationGO:001644410.014
regulation of primary metabolic processGO:00800903110.014
regulation of multicellular organismal processGO:00512392770.014
peptidyl threonine modificationGO:001821010.014
single organism reproductive processGO:0044702400.013
brain developmentGO:00074202930.013
negative regulation of mitosisGO:004583930.013
oocyte developmentGO:0048599140.013
regulation of dna metabolic processGO:0051052110.013
heart developmentGO:00075073130.013
positive regulation of nucleotide catabolic processGO:003081310.013
negative regulation of chromatin modificationGO:190330910.013
regulation of rna metabolic processGO:00512522240.013
regulation of organelle assemblyGO:190211540.013
regulation of protein bindingGO:004339330.013
multi organism reproductive processGO:0044703360.013
mitotic sister chromatid segregationGO:000007060.013
response to amino acidGO:004320020.013
nucleocytoplasmic transportGO:000691340.013
positive regulation of hydrolase activityGO:0051345130.013
astral microtubule organizationGO:003095310.012
cellular response to dna damage stimulusGO:0006974240.012
Human Mouse
endocytosisGO:0006897160.012
Worm
positive regulation of rna biosynthetic processGO:1902680570.012
regulation of cysteine type endopeptidase activityGO:2000116210.012
ribose phosphate metabolic processGO:0019693270.012
eye photoreceptor cell developmentGO:0042462300.012
regulation of mitotic cell cycle phase transitionGO:190199080.012
stem cell developmentGO:0048864820.012
macromolecule modificationGO:00434121110.012
cellular response to biotic stimulusGO:007121630.012
positive regulation of cell cycleGO:004578730.012
tissue regenerationGO:0042246740.012
mononuclear cell proliferationGO:003294310.012
photoreceptor cell developmentGO:0042461400.012
localization of cellGO:00516742440.012
nucleoside phosphate metabolic processGO:0006753280.012
regulation of bindingGO:005109830.012
chromatin modificationGO:0016568210.011
telomere maintenanceGO:000072310.011
positive regulation of cellular amine metabolic processGO:003324000.011
gtp catabolic processGO:000618420.011
regulation of programmed cell deathGO:00430671010.011
immune system developmentGO:00025201910.011
mucopolysaccharide metabolic processGO:190351020.011
cell cycle g1 s phase transitionGO:004484310.011
regulation of cellular component organizationGO:0051128860.011
protein targeting to nucleusGO:004474430.011
glycosaminoglycan metabolic processGO:003020390.011
positive regulation of programmed cell deathGO:0043068290.011
protein import into nucleusGO:000660630.011
cell divisionGO:0051301200.011
Worm
posttranscriptional gene silencing by rnaGO:003519430.011
regulation of protein import into nucleusGO:004230620.011
regulation of chromatin modificationGO:190330850.011
regulation of multicellular organism growthGO:004001440.011
g2 dna damage checkpointGO:003157230.011
polarized epithelial cell differentiationGO:003085940.011
developmental growthGO:00485891660.011
response to external stimulusGO:00096052640.011
regulation of protein localization to nucleusGO:190018020.011
stem cell maintenanceGO:001982740.011
dna methylationGO:000630680.011
pronuclear migrationGO:003504610.011
establishment of localization in cellGO:0051649770.011
positive regulation of nucleic acid templated transcriptionGO:1903508570.010
b cell differentiationGO:003018310.010
regulation of cellular amine metabolic processGO:003323800.010
gastrulationGO:00073692080.010
microtubule organizing center organizationGO:003102310.010
organelle fissionGO:0048285230.010
response to growth factorGO:0070848390.010
negative regulation of cell deathGO:0060548600.010
negative regulation of cellular catabolic processGO:003133030.010
cilium morphogenesisGO:0060271850.010

pold1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.042
Human
organ system cancerDOID:005068600.042
Human
disease of cellular proliferationDOID:1456600.042
Human
disease of anatomical entityDOID:700.025
thoracic cancerDOID:509300.023
nervous system diseaseDOID:86300.018
disease of mental healthDOID:15000.012
developmental disorder of mental healthDOID:006003700.012