Danio rerio

0 known processes

pvrl1a

poliovirus receptor-related 1a

pvrl1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
eye developmentGO:00016542770.995
Mouse
sensory organ developmentGO:00074233930.914
Mouse
camera type eye developmentGO:00430102220.777
Mouse
cell motilityGO:00488702440.558
brain developmentGO:00074202930.410
cellular biosynthetic processGO:00442492860.358
neuroblast proliferationGO:000740520.358
cell migrationGO:00164772370.341
retina development in camera type eyeGO:00600411460.318
Mouse
head developmentGO:00603223030.296
phagocytosisGO:000690930.279
chordate embryonic developmentGO:00430092710.261
regulation of protein polymerizationGO:003227120.231
transportGO:00068102200.230
Mouse
regulation of primary metabolic processGO:00800903110.226
single organism transportGO:00447652060.222
Mouse
cellular component movementGO:00069283350.211
regionalizationGO:00030022740.206
regulation of axonogenesisGO:0050770320.200
retina morphogenesis in camera type eyeGO:0060042790.200
guanosine containing compound catabolic processGO:190106920.198
oligodendrocyte differentiationGO:0048709230.196
locomotionGO:00400113130.181
stem cell proliferationGO:007208940.180
regulation of localizationGO:00328791040.177
proteolysis involved in cellular protein catabolic processGO:005160330.175
detection of abiotic stimulusGO:0009582240.175
positive regulation of transportGO:005105020.173
negative regulation of kinase activityGO:003367340.171
cortical actin cytoskeleton organizationGO:003086610.168
cell morphogenesis involved in differentiationGO:00009041950.167
central nervous system developmentGO:00074173870.166
nucleobase containing compound metabolic processGO:00061392740.164
ameboidal type cell migrationGO:00016671430.158
maintenance of locationGO:005123540.151
neuron developmentGO:00486662620.150
protein polymerizationGO:005125840.141
regulation of developmental processGO:00507932470.140
larval developmentGO:000216420.139
gene expressionGO:00104672520.137
cellular protein metabolic processGO:00442671290.137
cell part morphogenesisGO:00329902460.134
positive regulation of biological processGO:00485182530.132
regulation of nitrogen compound metabolic processGO:00511712510.130
photoreceptor cell differentiationGO:0046530550.130
localization of cellGO:00516742440.128
regulation of neurotransmitter transportGO:005158810.125
gland developmentGO:00487321430.124
establishment of cell polarityGO:0030010180.123
nucleobase containing compound biosynthetic processGO:00346542050.120
generation of neuronsGO:00486993850.119
regulation of synapse assemblyGO:005196330.119
response to radiationGO:0009314510.118
guanosine containing compound metabolic processGO:190106840.118
regulation of biological qualityGO:00650082630.117
neuron projection morphogenesisGO:00488121610.114
neurotransmitter transportGO:000683620.113
camera type eye photoreceptor cell differentiationGO:0060219190.113
regulation of apoptotic processGO:0042981980.111
camera type eye morphogenesisGO:00485931080.098
Mouse
eye morphogenesisGO:00485921440.093
Mouse
actin polymerization or depolymerizationGO:000815420.093
positive regulation of cellular component biogenesisGO:004408930.091
pectoral fin developmentGO:0033339500.091
protein modification processGO:00362111000.090
response to light stimulusGO:0009416460.088
determination of heart left right asymmetryGO:00613711170.088
neuron migrationGO:0001764220.088
regulation of membrane potentialGO:0042391230.087
regulation of cellular macromolecule biosynthetic processGO:20001122220.087
regulation of cell deathGO:00109411030.084
chemotaxisGO:00069351040.083
embryonic organ developmentGO:00485683810.083
regulation of synapse organizationGO:005080730.082
neuron differentiationGO:00301823530.082
eye photoreceptor cell differentiationGO:0001754450.081
retinoic acid receptor signaling pathwayGO:0048384160.080
nucleic acid metabolic processGO:00903042440.078
regulation of neuron differentiationGO:0045664560.076
epithelial tube morphogenesisGO:00605621480.075
nitrogen compound metabolic processGO:00068073190.074
positive regulation of macromolecule metabolic processGO:0010604930.074
single organism localizationGO:19025782250.074
Mouse
rna metabolic processGO:00160702190.071
response to vitaminGO:003327330.071
small molecule metabolic processGO:0044281770.070
positive regulation of cell cycleGO:004578730.069
inner ear developmentGO:00488391260.068
cellular component assemblyGO:00226071700.068
negative regulation of biological processGO:00485193040.068
multicellular organismal response to stressGO:003355520.067
single organism metabolic processGO:00447102170.067
morphogenesis of an epitheliumGO:00020093330.066
embryo development ending in birth or egg hatchingGO:00097922710.066
response to nutrientGO:000758430.066
cellular amine metabolic processGO:004410620.065
phosphate containing compound metabolic processGO:00067961080.065
deathGO:00162651210.065
cell proliferationGO:0008283800.064
retina layer formationGO:0010842240.064
regulation of macromolecule metabolic processGO:00602553170.064
cell projection organizationGO:00300302840.064
response to ketoneGO:190165410.063
regulation of cell shapeGO:000836010.062
organic cyclic compound metabolic processGO:19013603010.062
establishment of localizationGO:00512342440.061
Mouse
heterocycle metabolic processGO:00464832900.060
regulation of cellular ketone metabolic processGO:001056570.059
behaviorGO:0007610740.058
mesenchymal cell differentiationGO:0048762870.058
heart developmentGO:00075073130.057
regulation of gene expressionGO:00104682650.057
actin filament polymerizationGO:003004120.057
regulation of catalytic activityGO:0050790550.057
amine metabolic processGO:000930820.056
ion transmembrane transportGO:0034220910.056
lens development in camera type eyeGO:0002088220.056
Mouse
positive regulation of nucleobase containing compound metabolic processGO:0045935690.055
embryonic eye morphogenesisGO:0048048300.055
regulation of biosynthetic processGO:00098892500.055
regulation of extrinsic apoptotic signaling pathwayGO:200123630.054
programmed cell deathGO:00125011190.054
response to chemicalGO:00422213200.053
cortical cytoskeleton organizationGO:003086510.053
developmental growthGO:00485891660.053
chemosensory behaviorGO:000763510.052
cellular nitrogen compound metabolic processGO:00346412900.052
morphogenesis of embryonic epitheliumGO:0016331300.051
positive regulation of secretion by cellGO:190353210.050
response to stressGO:00069502630.050
cell morphogenesis involved in neuron differentiationGO:00486671630.049
stem cell divisionGO:001714510.048
lipid storageGO:001991510.048
actin filament based processGO:0030029640.048
heterocycle biosynthetic processGO:00181302150.048
anterior posterior pattern specificationGO:00099521520.048
photoreceptor cell developmentGO:0042461400.048
adult behaviorGO:003053420.048
regulation of anatomical structure morphogenesisGO:00226031300.047
segmentationGO:0035282970.047
monoamine transportGO:001584410.047
growthGO:00400071740.047
multicellular organismal signalingGO:0035637220.046
apoptotic processGO:00069151160.046
protein metabolic processGO:00195381830.046
regulation of nucleotide catabolic processGO:003081120.046
regulation of cellular metabolic processGO:00313233200.046
establishment or maintenance of cell polarityGO:0007163290.046
regulation of protein complex assemblyGO:004325430.046
glial cell developmentGO:0021782200.046
positive regulation of transcription dna templatedGO:0045893570.046
negative regulation of protein phosphorylationGO:000193340.045
regulation of multicellular organismal developmentGO:20000262230.045
response to drugGO:004249330.045
regulation of signalingGO:00230512350.045
neural retina developmentGO:0003407490.045
regulation of macromolecule biosynthetic processGO:00105562250.044
regulation of neurotransmitter secretionGO:004692810.044
embryonic organ morphogenesisGO:00485622740.044
cell fate commitmentGO:0045165990.044
ubiquitin dependent protein catabolic processGO:000651130.044
regulation of synaptic growth at neuromuscular junctionGO:000858210.043
glial cell differentiationGO:0010001420.043
single organism membrane fusionGO:004480120.043
regulation of cell sizeGO:0008361290.043
regulation of cellular component sizeGO:0032535300.042
regulation of neuron projection developmentGO:0010975400.042
cellular ketone metabolic processGO:0042180110.041
nucleobase containing small molecule metabolic processGO:0055086320.041
cell cycle g1 s phase transitionGO:004484310.041
organic cyclic compound biosynthetic processGO:19013622230.040
gliogenesisGO:0042063450.040
aromatic compound biosynthetic processGO:00194382170.040
dorsal motor nucleus of vagus nerve developmentGO:002174440.040
morphogenesis of an epithelial foldGO:006057110.039
carboxylic acid metabolic processGO:0019752220.039
single organism membrane organizationGO:0044802200.039
establishment or maintenance of apical basal cell polarityGO:0035088120.039
blood circulationGO:0008015870.039
neurotransmitter secretionGO:000726920.039
intracellular signal transductionGO:0035556850.038
regulation of multicellular organismal processGO:00512392770.038
sensory perception of light stimulusGO:0050953190.038
actin cytoskeleton organizationGO:0030036630.037
digestive tract developmentGO:00485652650.037
detection of external stimulusGO:0009581240.037
biosynthetic processGO:00090582940.037
heart morphogenesisGO:00030071560.037
regulation of response to stimulusGO:00485832690.037
vasculature developmentGO:00019442780.036
cellular aromatic compound metabolic processGO:00067252950.035
response to amino acidGO:004320020.035
regulation of growthGO:0040008420.035
establishment or maintenance of bipolar cell polarityGO:0061245120.035
regulation of cellular amine metabolic processGO:003323800.035
cell projection assemblyGO:0030031640.035
regulation of dendrite developmentGO:005077330.034
negative regulation of gene expressionGO:0010629650.034
regulation of molecular functionGO:0065009700.034
embryonic epithelial tube formationGO:0001838170.034
organ formationGO:0048645170.034
regulation of programmed cell deathGO:00430671010.034
cognitionGO:005089010.033
proteasomal protein catabolic processGO:001049820.033
autophagyGO:000691440.033
positive regulation of cell adhesionGO:004578510.032
transcription dna templatedGO:00063511810.032
spermatid developmentGO:000728620.032
cell deathGO:00082191210.032
organonitrogen compound metabolic processGO:1901564740.032
brain morphogenesisGO:0048854180.032
inner ear morphogenesisGO:0042472630.032
gtp metabolic processGO:004603940.031
cellular component biogenesisGO:00440851780.031
regulation of wound healingGO:006104120.031
digestive tract morphogenesisGO:00485462310.031
negative regulation of protein kinase activityGO:000646940.031
circulatory system processGO:0003013870.031
intracellular receptor signaling pathwayGO:0030522300.030
desmosome organizationGO:000293430.030
Mouse
lateral line system developmentGO:0048925760.030
small gtpase mediated signal transductionGO:000726480.030
positive regulation of apoptotic processGO:0043065290.029
neural crest cell developmentGO:0014032620.029
synaptic growth at neuromuscular junctionGO:005112420.029
protein localizationGO:0008104400.029
macromolecule modificationGO:00434121110.029
cellular component morphogenesisGO:00329893360.029
epithelial tube formationGO:0072175190.028
cellular response to organic substanceGO:00713101050.028
hindbrain developmentGO:0030902910.028
regulation of cell morphogenesis involved in differentiationGO:0010769380.028
neural precursor cell proliferationGO:0061351200.028
digestive system developmentGO:00551232890.028
cellular amino acid metabolic processGO:000652070.028
cellular macromolecule metabolic processGO:00442603910.027
neuron deathGO:0070997210.027
cellular response to acid chemicalGO:007122980.027
positive regulation of cellular biosynthetic processGO:0031328680.027
neuron neuron synaptic transmissionGO:000727010.027
primary neural tube formationGO:001402010.027
tube closureGO:006060610.027
regulation of cellular amino acid metabolic processGO:000652100.026
gtp catabolic processGO:000618420.026
detection of stimulusGO:0051606290.026
regulation of metabolic processGO:00192223590.026
cellular component maintenanceGO:004395430.026
regulation of neurogenesisGO:0050767870.026
negative regulation of chromosome organizationGO:200125110.026
action potentialGO:0001508190.026
embryonic cranial skeleton morphogenesisGO:0048701900.026
positive regulation of nucleoside metabolic processGO:004597910.026
negative regulation of nucleobase containing compound metabolic processGO:0045934590.026
establishment of epithelial cell polarityGO:009016220.026
neural tube developmentGO:0021915620.026
organic substance biosynthetic processGO:19015762890.025
cellular protein modification processGO:00064641000.025
leukocyte migrationGO:0050900150.025
outflow tract morphogenesisGO:000315110.025
negative regulation of epithelial cell proliferationGO:005068010.025
calcium ion importGO:007050940.025
positive regulation of purine nucleotide catabolic processGO:003312310.025
single organism organelle organizationGO:19025891990.025
cell morphogenesisGO:00009022890.024
digestive tract mesoderm developmentGO:000750210.024
neurological system processGO:0050877620.024
ribonucleotide metabolic processGO:0009259270.024
regulation of cell communicationGO:00106462320.024
nucleic acid templated transcriptionGO:00976591810.024
positive regulation of gene expressionGO:0010628710.023
oxoacid metabolic processGO:0043436310.023
retinal cone cell developmentGO:004654980.023
gastrulationGO:00073692080.023
specification of symmetryGO:00097992040.023
regulation of transcription dna templatedGO:00063552130.023
calcium mediated signalingGO:001972220.023
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.023
response to external stimulusGO:00096052640.022
regulation of transcription from rna polymerase ii promoterGO:00063571140.022
ras protein signal transductionGO:000726570.022
cellular response to endogenous stimulusGO:0071495680.022
positive regulation of map kinase activityGO:004340630.022
regulation of nucleic acid templated transcriptionGO:19035062130.022
sensory organ morphogenesisGO:00905962000.022
Mouse
inositol lipid mediated signalingGO:004801720.022
regulation of inflammatory responseGO:005072720.022
macromolecular complex subunit organizationGO:0043933740.022
locomotor rhythmGO:004547530.022
regulation of reproductive processGO:200024140.022
positive regulation of synapse assemblyGO:005196510.022
embryonic skeletal system morphogenesisGO:0048704930.022
response to hormoneGO:0009725480.022
forebrain cell migrationGO:002188510.021
regulation of response to nutrient levelsGO:003210710.021
regulation of intracellular protein transportGO:003315730.021
cell projection morphogenesisGO:00488582440.021
detection of light stimulusGO:0009583120.021
startle responseGO:000196440.020
tissue migrationGO:0090130370.020
eye photoreceptor cell developmentGO:0042462300.020
skeletal system morphogenesisGO:00487051020.020
visual perceptionGO:0007601170.020
rho protein signal transductionGO:000726650.020
positive regulation of cell developmentGO:0010720250.020
stem cell maintenanceGO:001982740.020
positive regulation of nitrogen compound metabolic processGO:0051173690.020
positive regulation of rna biosynthetic processGO:1902680570.020
fin developmentGO:0033333770.020
response to woundingGO:00096111160.020
protein phosphorylationGO:0006468470.020
negative regulation of macromolecule metabolic processGO:0010605760.020
hormone metabolic processGO:0042445190.020
negative regulation of nuclear divisionGO:005178430.019
cation transmembrane transportGO:0098655650.019
tube morphogenesisGO:00352393490.019
regulation of mrna processingGO:005068430.019
phosphorylationGO:0016310690.019
pigmentationGO:0043473850.019
regulation of autophagyGO:001050630.019
organelle fusionGO:004828430.019
regulation of cell migrationGO:0030334400.019
negative regulation of catalytic activityGO:0043086210.019
cellular response to hormone stimulusGO:0032870390.019
neutrophil migrationGO:1990266100.019
cellular nitrogen compound biosynthetic processGO:00442712180.019
axonogenesisGO:00074091520.019
cell surface receptor signaling pathwayGO:00071663250.019
urogenital system developmentGO:0001655970.019
spermatid differentiationGO:004851520.019
positive regulation of dna metabolic processGO:005105410.019
enzyme linked receptor protein signaling pathwayGO:00071671060.019
phosphatidylinositol mediated signalingGO:004801520.019
blood vessel morphogenesisGO:00485142160.019
regulation of cellular protein metabolic processGO:0032268520.019
regulation of cell developmentGO:00602841000.018
purine nucleotide metabolic processGO:0006163270.018
g1 s transition of mitotic cell cycleGO:000008210.018
epithelial cell migrationGO:0010631250.018
regulation of dna replicationGO:000627530.018
negative regulation of catabolic processGO:000989530.018
glycerophospholipid biosynthetic processGO:004647410.017
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.017
positive regulation of wound healingGO:009030310.017
developmental pigmentationGO:0048066480.017
modification dependent macromolecule catabolic processGO:004363230.017
olfactory lobe developmentGO:002198840.017
convergent extensionGO:00600261180.017
muscle tissue developmentGO:00605371100.017
positive regulation of multicellular organismal processGO:0051240520.017
retinal cone cell differentiationGO:0042670120.017
regulation of neuron migrationGO:200122220.017
regulation of cell projection organizationGO:0031344440.017
positive regulation of cell deathGO:0010942290.017
regulation of signal transductionGO:00099662250.017
endomembrane system organizationGO:0010256130.017
phagocytosis engulfmentGO:000691110.017
adherens junction organizationGO:003433240.017
endosomal transportGO:001619720.017
positive regulation of chromosome organizationGO:200125210.017
positive regulation of cellular amine metabolic processGO:003324000.017
response to corticosteroidGO:003196010.017
regulation of sodium ion transmembrane transporter activityGO:200064910.016
cellular macromolecule biosynthetic processGO:00346452240.016
regulation of filopodium assemblyGO:005148920.016
kupffer s vesicle developmentGO:0070121500.016
central nervous system neuron developmentGO:0021954290.016
cellular nitrogen compound catabolic processGO:0044270150.016
axon developmentGO:00615641660.016
exocytosisGO:000688710.016
lipid metabolic processGO:0006629520.016
cellular response to chemical stimulusGO:00708871570.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.016
regulation of response to extracellular stimulusGO:003210410.016
negative regulation of cell communicationGO:0010648960.016
positive regulation of inflammatory responseGO:005072910.016
neuron projection guidanceGO:0097485860.016
regulation of rna biosynthetic processGO:20011412130.016
axon guidanceGO:0007411860.015
positive regulation of rna metabolic processGO:0051254590.015
negative regulation of apoptotic processGO:0043066550.015
negative regulation of cellular metabolic processGO:0031324770.015
cardiac conductionGO:006133730.015
keratinocyte differentiationGO:003021600.015
cellular response to prostaglandin stimulusGO:007137930.015
regulation of purine nucleotide catabolic processGO:003312120.015
regulation of gtp catabolic processGO:003312420.015
photoreceptor cell fate commitmentGO:004655210.015
regulation of cellular biosynthetic processGO:00313262450.015
regulation of response to external stimulusGO:0032101310.015
positive regulation of epithelial cell migrationGO:001063420.015
astrocyte differentiationGO:004870810.015
multicellular organism growthGO:003526440.015
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.015
developmental cell growthGO:0048588520.015
positive regulation of cell divisionGO:005178120.015
cardiac chamber morphogenesisGO:0003206120.015
regulation of cell cycle phase transitionGO:190198780.015
specification of organ identityGO:001009220.015
regulation of rho protein signal transductionGO:003502320.015
positive regulation of neuron deathGO:190121610.015
tissue remodelingGO:004877140.015
detection of stimulus involved in sensory perceptionGO:0050906210.015
nucleocytoplasmic transportGO:000691340.014
melanosome transportGO:0032402190.014
cell junction maintenanceGO:003433120.014
carbon dioxide transportGO:001567030.014
motor neuron axon guidanceGO:0008045230.014
negative regulation of mitosisGO:004583930.014
central nervous system neuron axonogenesisGO:0021955180.014
negative regulation of signalingGO:0023057960.014
taxisGO:00423301090.014
postsynaptic membrane organizationGO:000194130.014
positive regulation of programmed cell deathGO:0043068290.014
regulation of axon guidanceGO:190266780.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
regulation of intracellular signal transductionGO:1902531570.014
granulocyte migrationGO:0097530110.014
stem cell developmentGO:0048864820.014
ribose phosphate metabolic processGO:0019693270.014
regulation of extent of cell growthGO:0061387290.014
negative regulation of nitrogen compound metabolic processGO:0051172590.013
regulation of hormone secretionGO:004688320.013
regulation of protein catabolic processGO:004217610.013
regulation of stem cell differentiationGO:200073640.013
regulation of growth rateGO:004000910.013
regulation of postsynaptic membrane potentialGO:006007810.013
cytoskeleton organizationGO:0007010960.013
regulation of epithelial to mesenchymal transitionGO:001071730.013
positive regulation of glucose transportGO:001082810.013
hormone transportGO:000991420.013
membrane hyperpolarizationGO:006008110.013
positive regulation of cell projection organizationGO:003134690.013
regulation of cellular protein catabolic processGO:190336210.013
signal transduction in absence of ligandGO:003803410.013
desmosome assemblyGO:000215920.013
nuclear migrationGO:000709730.013
ear developmentGO:00435831270.013
regulation of circadian rhythmGO:004275240.013
positive regulation of neuron projection developmentGO:001097690.013
response to hexoseGO:000974630.013
morphogenesis of follicular epitheliumGO:001633310.013
positive regulation of cell differentiationGO:0045597300.013
regulation of neutrophil migrationGO:190262260.013
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.013
Mouse
positive regulation of lipid metabolic processGO:004583410.013
negative regulation of cell deathGO:0060548600.013
system processGO:00030081850.013
lamellipodium assemblyGO:003003210.013
water homeostasisGO:003010440.013
rna biosynthetic processGO:00327741810.013
exocrine pancreas developmentGO:0031017280.012
positive regulation of epithelial cell proliferationGO:005067910.012
catabolic processGO:0009056320.012
establishment of endothelial barrierGO:006102830.012
stem cell differentiationGO:00488631170.012
phosphorus metabolic processGO:00067931090.012
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.012
negative regulation of cellular processGO:00485232830.012
positive regulation of cellular metabolic processGO:0031325940.012
fertilizationGO:000956630.012
negative regulation of cellular biosynthetic processGO:0031327550.012
optokinetic behaviorGO:000763490.012
response to carbohydrateGO:000974330.012
regulation of transferase activityGO:0051338160.012
fatty acid transportGO:001590810.012
neuroblast fate commitmentGO:001401710.012
negative regulation of programmed cell deathGO:0043069580.012
histone h3 k9 modificationGO:006164750.012
regulation of protein modification processGO:0031399290.012
positive regulation of cellular catabolic processGO:003133130.012
lytic vacuole organizationGO:008017110.012
homeostatic processGO:00425921420.012
negative regulation of transcription dna templatedGO:0045892450.012
endothelial cell fate commitmentGO:006083930.012
regulation of organ morphogenesisGO:2000027350.012
regulation of cellular component movementGO:0051270550.012
cell migration involved in heart developmentGO:0060973220.011
modification dependent protein catabolic processGO:001994130.011
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.011
positive regulation of secretionGO:005104710.011
peripheral nervous system developmentGO:0007422550.011
regulation of cell differentiationGO:00455951420.011
membrane fusionGO:006102520.011
negative regulation of secretionGO:005104820.011
tissue regenerationGO:0042246740.011
regulation of locomotionGO:0040012550.011
membrane invaginationGO:001032410.011
cell adhesionGO:0007155400.011
Mouse
positive regulation of axonogenesisGO:005077260.011
cellular macromolecular complex assemblyGO:0034622240.011
positive regulation of cellular processGO:00485222010.011
negative regulation of cellular catabolic processGO:003133030.011
morphogenesis of a branching structureGO:0001763210.011
regulation of bindingGO:005109830.011

pvrl1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.161
musculoskeletal system diseaseDOID:1700.023
disease of metabolismDOID:001466700.016
nervous system diseaseDOID:86300.016
cardiovascular system diseaseDOID:128700.013