Danio rerio

0 known processes

rhoub

ras homolog gene family, member Ub

(Aliases: wu:fb18g01,zgc:110357)

rhoub biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
central nervous system developmentGO:00074173870.605
response to external stimulusGO:00096052640.527
chordate embryonic developmentGO:00430092710.336
chemotaxisGO:00069351040.334
tube morphogenesisGO:00352393490.301
Zebrafish
cellular ketone metabolic processGO:0042180110.290
morphogenesis of an epitheliumGO:00020093330.255
Zebrafish
lateral line developmentGO:0048882660.246
oxoacid metabolic processGO:0043436310.235
organic acid metabolic processGO:0006082310.229
brain developmentGO:00074202930.226
regulation of multicellular organismal developmentGO:20000262230.215
carboxylic acid metabolic processGO:0019752220.178
head developmentGO:00603223030.172
heart developmentGO:00075073130.171
Zebrafish
positive regulation of map kinase activityGO:004340630.170
skeletal system developmentGO:00015011810.169
cell morphogenesisGO:00009022890.167
larval developmentGO:000216420.157
cell projection morphogenesisGO:00488582440.157
small molecule metabolic processGO:0044281770.144
generation of neuronsGO:00486993850.142
lateral line system developmentGO:0048925760.136
cellular component assemblyGO:00226071700.135
regulation of phospholipase c activityGO:190027410.134
regulation of myelinationGO:003164110.130
activation of mapk activityGO:000018730.127
regulation of cellular ketone metabolic processGO:001056570.127
taxisGO:00423301090.126
positive regulation of muscle tissue developmentGO:190186310.125
regulation of cellular amine metabolic processGO:003323800.122
sensory organ developmentGO:00074233930.121
hepaticobiliary system developmentGO:0061008980.116
sensory system developmentGO:0048880760.113
embryo development ending in birth or egg hatchingGO:00097922710.112
cilium morphogenesisGO:0060271850.112
locomotionGO:00400113130.112
mesenchyme developmentGO:00604851270.110
stem cell developmentGO:0048864820.108
regulation of cellular amino acid metabolic processGO:000652100.107
stem cell differentiationGO:00488631170.106
cell part morphogenesisGO:00329902460.106
regulation of peptidyl tyrosine phosphorylationGO:005073010.103
positive regulation of stress activated mapk cascadeGO:003287430.103
protein localization to nucleusGO:003450430.103
skeletal muscle organ developmentGO:0060538780.102
regulation of phosphorus metabolic processGO:0051174430.101
sequestering of calcium ionGO:005120830.098
agingGO:000756820.097
cellular amino acid metabolic processGO:000652070.097
cellular component morphogenesisGO:00329893360.094
digestive tract developmentGO:00485652650.094
Zebrafish
skeletal system morphogenesisGO:00487051020.094
endodermal cell fate determinationGO:000749320.093
negative regulation of cellular processGO:00485232830.093
morphogenesis of a branching structureGO:0001763210.093
response to chemicalGO:00422213200.092
single organism metabolic processGO:00447102170.091
homeostatic processGO:00425921420.091
pancreas developmentGO:0031016840.089
cellular response to endogenous stimulusGO:0071495680.086
signal transductionGO:00071654550.086
response to stressGO:00069502630.083
midbrain developmentGO:0030901280.083
regulation of cellular macromolecule biosynthetic processGO:20001122220.083
neuron developmentGO:00486662620.081
positive regulation of signalingGO:0023056560.081
regulation of wound healingGO:006104120.081
regulation of metabolic processGO:00192223590.081
positive regulation of cell communicationGO:0010647560.080
positive regulation of cell cycleGO:004578730.080
neuronal action potentialGO:0019228180.079
peptide transportGO:001583310.078
positive regulation of cellular processGO:00485222010.077
morphogenesis of embryonic epitheliumGO:0016331300.076
neural tube developmentGO:0021915620.075
pigmentationGO:0043473850.074
cellular response to external stimulusGO:007149620.074
regulation of purine nucleotide catabolic processGO:003312120.073
cell projection organizationGO:00300302840.073
neuron projection developmentGO:00311751800.069
positive regulation of phospholipase c activityGO:001086310.069
regulation of hydrolase activityGO:0051336280.069
organic cyclic compound metabolic processGO:19013603010.068
appendage developmentGO:0048736800.068
epithelial tube formationGO:0072175190.068
regulation of multicellular organismal processGO:00512392770.067
positive regulation of metabolic processGO:00098931080.067
positive regulation of cellular amino acid metabolic processGO:004576400.067
epithelial cell differentiationGO:00308551160.067
cell morphogenesis involved in differentiationGO:00009041950.065
neuron differentiationGO:00301823530.064
cell morphogenesis involved in neuron differentiationGO:00486671630.064
cell proliferation in forebrainGO:002184630.063
cell fate specificationGO:0001708680.063
mesenchymal cell differentiationGO:0048762870.063
ear developmentGO:00435831270.062
intracellular signal transductionGO:0035556850.062
cell fate commitmentGO:0045165990.062
liver developmentGO:0001889960.061
response to organic substanceGO:00100331530.060
embryonic organ morphogenesisGO:00485622740.060
regulation of primary metabolic processGO:00800903110.060
regulation of localizationGO:00328791040.060
neuron projection guidanceGO:0097485860.060
anterior posterior pattern specificationGO:00099521520.059
positive regulation of transportGO:005105020.058
regulation of cell deathGO:00109411030.058
response to other organismGO:0051707970.057
regulation of signalingGO:00230512350.057
regulation of catalytic activityGO:0050790550.057
phagocytosisGO:000690930.056
positive regulation of macromolecule metabolic processGO:0010604930.056
cellular amine metabolic processGO:004410620.056
regionalizationGO:00030022740.055
organonitrogen compound metabolic processGO:1901564740.054
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.054
tube formationGO:0035148250.054
primary neural tube formationGO:001402010.054
post embryonic organ developmentGO:004856940.053
blood vessel morphogenesisGO:00485142160.053
regulation of sequestering of calcium ionGO:005128240.053
cellular response to chemical stimulusGO:00708871570.052
positive regulation of muscle organ developmentGO:004863610.052
cellular macromolecule metabolic processGO:00442603910.052
regulation of intracellular protein transportGO:003315730.051
embryonic epithelial tube formationGO:0001838170.051
system processGO:00030081850.051
macromolecule modificationGO:00434121110.050
embryonic limb morphogenesisGO:003032620.050
macromolecular complex assemblyGO:0065003350.050
regulation of neuron differentiationGO:0045664560.050
organic substance biosynthetic processGO:19015762890.050
neuron projection morphogenesisGO:00488121610.049
outflow tract morphogenesisGO:000315110.049
response to biotic stimulusGO:0009607970.049
transportGO:00068102200.049
regulation of biosynthetic processGO:00098892500.049
response to external biotic stimulusGO:0043207970.047
maintenance of locationGO:005123540.047
ameboidal type cell migrationGO:00016671430.046
lipid storageGO:001991510.046
regulation of biological qualityGO:00650082630.046
transmembrane transportGO:00550851200.046
positive regulation of cellular metabolic processGO:0031325940.046
regulation of cellular protein metabolic processGO:0032268520.046
transmission of nerve impulseGO:0019226190.045
protein targeting to nucleusGO:004474430.045
ras protein signal transductionGO:000726570.045
programmed cell deathGO:00125011190.044
regulation of nucleocytoplasmic transportGO:004682220.044
positive regulation of striated muscle tissue developmentGO:004584410.044
neuroblast proliferationGO:000740520.044
appendage morphogenesisGO:0035107560.043
cellular amino acid biosynthetic processGO:000865220.043
single organism localizationGO:19025782250.042
positive regulation of catabolic processGO:000989640.042
positive regulation of cellular amine metabolic processGO:003324000.042
regulation of stem cell differentiationGO:200073640.042
cellular aromatic compound metabolic processGO:00067252950.042
central nervous system myelinationGO:002201020.042
regulation of phosphate metabolic processGO:0019220430.041
regulation of nucleobase containing compound metabolic processGO:00192192500.041
stem cell maintenanceGO:001982740.041
cranial nerve developmentGO:0021545420.041
nucleobase containing compound metabolic processGO:00061392740.041
cellular protein metabolic processGO:00442671290.041
axon ensheathment in central nervous systemGO:003229120.040
regulation of cellular metabolic processGO:00313233200.040
ensheathment of neuronsGO:0007272180.040
regulation of nucleoside metabolic processGO:000911820.040
rostrocaudal neural tube patterningGO:0021903290.040
nerve developmentGO:0021675450.039
nucleic acid templated transcriptionGO:00976591810.039
cell motilityGO:00488702440.039
regulation of cell differentiationGO:00455951420.039
positive regulation of signal transductionGO:0009967560.039
small gtpase mediated signal transductionGO:000726480.039
transcription from rna polymerase iii promoterGO:000638310.038
regulation of extrinsic apoptotic signaling pathwayGO:200123630.038
nitrogen compound metabolic processGO:00068073190.038
positive regulation of cell activationGO:005086710.038
gene expressionGO:00104672520.037
striated muscle tissue developmentGO:00147061100.037
single organism nuclear importGO:190259330.037
epithelial tube morphogenesisGO:00605621480.037
establishment of localizationGO:00512342440.037
regulation of phospholipase activityGO:001051720.037
cartilage developmentGO:0051216960.037
regulation of mrna processingGO:005068430.036
cell cell signalingGO:0007267520.036
multicellular organism growthGO:003526440.036
cellular component movementGO:00069283350.036
cellular nitrogen compound metabolic processGO:00346412900.036
regulation of response to stimulusGO:00485832690.035
action potentialGO:0001508190.035
regulation of peptidase activityGO:0052547230.035
synaptic transmission cholinergicGO:000727140.035
regulation of cell morphogenesis involved in differentiationGO:0010769380.035
cellular response to organic substanceGO:00713101050.035
connective tissue developmentGO:0061448990.034
neural tube formationGO:0001841160.034
neuroblast differentiationGO:001401610.034
sequestering of metal ionGO:005123830.034
embryonic cranial skeleton morphogenesisGO:0048701900.034
sensory organ morphogenesisGO:00905962000.033
defense response to other organismGO:0098542330.033
positive regulation of rna metabolic processGO:0051254590.033
mechanosensory lateral line system developmentGO:0048881490.033
posterior lateral line developmentGO:0048916380.033
cellular biosynthetic processGO:00442492860.032
skeletal muscle tissue developmentGO:0007519670.032
positive regulation of immune effector processGO:000269930.032
epidermis developmentGO:0008544480.032
developmental programmed cell deathGO:001062340.032
extrinsic apoptotic signaling pathwayGO:009719130.032
eye developmentGO:00016542770.032
paraxial mesoderm developmentGO:004833980.031
regulation of nucleotide catabolic processGO:003081120.031
multi organism cellular processGO:004476420.031
protein metabolic processGO:00195381830.031
aromatic compound biosynthetic processGO:00194382170.031
midbrain hindbrain boundary developmentGO:0030917230.031
neuroblast fate commitmentGO:001401710.031
oxidation reduction processGO:0055114410.030
negative regulation of protein phosphorylationGO:000193340.030
embryonic skeletal system developmentGO:0048706970.030
mesenchymal cell developmentGO:0014031780.029
nucleocytoplasmic transportGO:000691340.029
regulation of nitrogen compound metabolic processGO:00511712510.029
growthGO:00400071740.029
translational initiationGO:000641330.029
calcium ion transport into cytosolGO:006040230.029
multicellular organismal signalingGO:0035637220.029
gland developmentGO:00487321430.029
regulation of system processGO:0044057400.029
positive regulation of response to stimulusGO:0048584800.028
regulation of cytoplasmic transportGO:190364940.028
axon ensheathmentGO:0008366180.028
negative regulation of macromolecule metabolic processGO:0010605760.028
macromolecule biosynthetic processGO:00090592270.028
positive regulation of jnk cascadeGO:004633030.028
cellular component biogenesisGO:00440851780.028
renal system developmentGO:0072001940.027
cell migrationGO:00164772370.027
axon developmentGO:00615641660.027
neural precursor cell proliferationGO:0061351200.027
guanosine containing compound catabolic processGO:190106920.027
regulation of macromolecule metabolic processGO:00602553170.027
transcription dna templatedGO:00063511810.027
regulation of transcription from rna polymerase iii promoterGO:000635910.026
positive regulation of cytokine productionGO:000181920.026
interspecies interaction between organismsGO:004441940.026
negative regulation of sequestering of calcium ionGO:005128340.026
ion transmembrane transportGO:0034220910.026
regulation of neurogenesisGO:0050767870.026
regulation of stem cell proliferationGO:007209120.026
mesoderm developmentGO:0007498880.026
neurological system processGO:0050877620.025
neuron fate determinationGO:004866420.025
axonogenesisGO:00074091520.025
heterocycle metabolic processGO:00464832900.025
response to endogenous stimulusGO:0009719830.025
nuclear transportGO:005116940.025
regulation of cellular component organizationGO:0051128860.025
lipid homeostasisGO:005508830.025
embryonic appendage morphogenesisGO:0035113300.025
phosphate containing compound metabolic processGO:00067961080.024
chemical homeostasisGO:0048878490.024
embryonic skeletal system morphogenesisGO:0048704930.024
regulation of cell communicationGO:00106462320.024
positive regulation of biosynthetic processGO:0009891680.024
localization of cellGO:00516742440.024
mucopolysaccharide metabolic processGO:190351020.024
somite developmentGO:0061053960.024
developmental maturationGO:0021700340.024
negative regulation of cellular protein metabolic processGO:0032269160.024
regulation of cardiac muscle tissue developmentGO:005502410.024
defense response to gram negative bacteriumGO:005082980.023
regulation of protein localization to nucleusGO:190018020.023
muscle organ developmentGO:00075171010.023
cellular response to biotic stimulusGO:007121630.023
morphogenesis of an epithelial sheetGO:0002011490.023
Zebrafish
phosphorus metabolic processGO:00067931090.023
regulation of transcription from rna polymerase ii promoterGO:00063571140.023
pectoral fin developmentGO:0033339500.023
negative regulation of cytokine productionGO:000181810.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.022
vasculature developmentGO:00019442780.022
hard palate developmentGO:006002240.022
cellular component assembly involved in morphogenesisGO:00109271070.022
regulation of macromolecule biosynthetic processGO:00105562250.022
nucleic acid metabolic processGO:00903042440.022
striated muscle cell differentiationGO:00511461290.022
regulation of fatty acid metabolic processGO:001921710.022
rhombomere 5 developmentGO:002157140.022
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.022
branching morphogenesis of a nerveGO:004875540.022
negative regulation of biological processGO:00485193040.022
retina development in camera type eyeGO:00600411460.022
nucleobase containing compound biosynthetic processGO:00346542050.022
myelin assemblyGO:003228810.021
stem cell divisionGO:001714510.021
regulation of cell shapeGO:000836010.021
establishment of localization in cellGO:0051649770.021
regulation of gtp catabolic processGO:003312420.021
kidney developmentGO:0001822920.021
regulation of protein catabolic processGO:004217610.021
macromolecular complex subunit organizationGO:0043933740.021
positive regulation of cellular catabolic processGO:003133130.021
hindbrain developmentGO:0030902910.021
nuclear importGO:005117030.021
hindbrain morphogenesisGO:0021575220.021
regulation of lipase activityGO:006019120.021
signal transduction in absence of ligandGO:003803410.021
regulation of growth rateGO:004000910.021
ion transportGO:00068111140.021
negative regulation of cell deathGO:0060548600.021
rna biosynthetic processGO:00327741810.020
angiogenesisGO:00015251580.020
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.020
regulation of anatomical structure morphogenesisGO:00226031300.020
response to woundingGO:00096111160.020
cellular response to retinoic acidGO:007130010.020
tissue regenerationGO:0042246740.020
fin developmentGO:0033333770.020
regulation of microtubule cytoskeleton organizationGO:007050730.020
regulation of neurological system processGO:003164420.020
regulation of protein kinase activityGO:0045859150.020
protein import into nucleusGO:000660630.020
protein importGO:001703830.019
inner ear developmentGO:00488391260.019
amine metabolic processGO:000930820.019
heterocycle biosynthetic processGO:00181302150.019
embryonic viscerocranium morphogenesisGO:0048703520.019
tube closureGO:006060610.019
neural crest cell developmentGO:0014032620.019
regulation of gtpase activityGO:004308720.019
positive regulation of protein complex assemblyGO:003133420.019
otolith developmentGO:0048840320.019
negative regulation of cellular metabolic processGO:0031324770.019
gtp metabolic processGO:004603940.019
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.019
regulation of nucleic acid templated transcriptionGO:19035062130.019
cellular macromolecular complex assemblyGO:0034622240.019
regulation of gene expressionGO:00104682650.018
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.018
germ line stem cell maintenanceGO:003071820.018
embryonic organ developmentGO:00485683810.018
water homeostasisGO:003010440.018
cytoskeleton organizationGO:0007010960.018
positive regulation of purine nucleotide catabolic processGO:003312310.018
microtubule based processGO:0007017600.018
somatic muscle developmentGO:000752540.018
positive regulation of cellular component biogenesisGO:004408930.017
positive regulation of cytosolic calcium ion concentrationGO:000720440.017
positive regulation of wound healingGO:009030310.017
immune system processGO:00023762410.017
neural tube patterningGO:0021532330.017
i kappab kinase nf kappab signalingGO:000724940.017
positive regulation of translationGO:004572710.017
sensory perception of painGO:001923310.017
regulation of protein import into nucleusGO:004230620.017
negative regulation of multicellular organismal processGO:0051241690.017
establishment of protein localization to organelleGO:007259440.017
single organism transportGO:00447652060.017
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.017
neural retina developmentGO:0003407490.017
apoptotic processGO:00069151160.017
regulation of mesoderm developmentGO:2000380110.017
regulation of transportGO:0051049450.016
regulation of cell fate commitmentGO:0010453220.016
hormone biosynthetic processGO:004244630.016
fin regenerationGO:0031101510.016
regulation of nervous system developmentGO:0051960900.016
erk1 and erk2 cascadeGO:007037140.016
synaptic target recognitionGO:000803910.016
regulation of rho protein signal transductionGO:003502320.016
regulation of heart growthGO:006042020.016
muscle tissue developmentGO:00605371100.016
regulation of canonical wnt signaling pathwayGO:0060828340.016
rna metabolic processGO:00160702190.016
dendrite guidanceGO:007098300.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
photoreceptor cell differentiationGO:0046530550.016
morphogenesis of a branching epitheliumGO:0061138160.016
wnt signaling pathway planar cell polarity pathwayGO:006007140.016
macromolecular complex disassemblyGO:003298410.016
regulation of intracellular signal transductionGO:1902531570.016
regulation of apoptotic processGO:0042981980.016
sensory perception of chemical stimulusGO:000760630.016
glucose homeostasisGO:004259310.016
cellular response to oxygen levelsGO:007145310.016
biosynthetic processGO:00090582940.016
regulation of molecular functionGO:0065009700.016
negative regulation of stem cell differentiationGO:200073720.015
embryonic pectoral fin morphogenesisGO:0035118240.015
fin morphogenesisGO:0033334530.015
positive regulation of nucleotide catabolic processGO:003081310.015
symbiosis encompassing mutualism through parasitismGO:004440340.015
axon midline choice point recognitionGO:001619940.015
carboxylic acid catabolic processGO:004639530.015
regulation of blood coagulationGO:003019310.015
endoderm formationGO:0001706290.015
regulation of protein serine threonine kinase activityGO:007190070.015
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.015
protein phosphorylationGO:0006468470.015
regulation of gastrulationGO:0010470240.015
cell chemotaxisGO:0060326170.015
negative regulation of cell differentiationGO:0045596460.015
pigment cell differentiationGO:0050931380.015
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.015
cell divisionGO:0051301200.015
cellular response to lipidGO:0071396390.015
response to acid chemicalGO:0001101170.015
cytosolic calcium ion transportGO:006040130.015
positive regulation of nitrogen compound metabolic processGO:0051173690.014
detection of chemical stimulusGO:000959340.014
negative regulation of protein metabolic processGO:0051248160.014
regulation of cytokine productionGO:000181730.014
phosphorylationGO:0016310690.014
epidermal cell fate specificationGO:000995740.014
regulation of production of molecular mediator of immune responseGO:000270010.014
positive regulation of leukocyte mediated immunityGO:000270510.014
autophagyGO:000691440.014
guanosine containing compound metabolic processGO:190106840.014
sensory perceptionGO:0007600390.014
specification of organ identityGO:001009220.014
segmentationGO:0035282970.014
regulation of cell activationGO:005086510.014
regulation of cell growthGO:0001558290.014
camera type eye photoreceptor cell differentiationGO:0060219190.014
inositol lipid mediated signalingGO:004801720.014
positive regulation of gtpase activityGO:004354710.014
positive regulation of secretion by cellGO:190353210.014
compound eye developmentGO:004874920.014
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.014
positive regulation of protein metabolic processGO:0051247230.014
regulation of phosphorylationGO:0042325260.014
negative regulation of embryonic developmentGO:0045992110.014
single organism organelle organizationGO:19025891990.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
response to glucoseGO:000974930.014
myoblast fusionGO:0007520100.013
regulation of cellular response to stressGO:0080135200.013
positive regulation of cellular biosynthetic processGO:0031328680.013
regulation of cellular biosynthetic processGO:00313262450.013
gtp catabolic processGO:000618420.013
regulation of response to external stimulusGO:0032101310.013
regulation of cell motilityGO:2000145460.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
regulation of behaviorGO:0050795240.013
actin mediated cell contractionGO:007025210.013
cognitionGO:005089010.013
regulation of hemostasisGO:190004610.013
organelle organizationGO:00069962270.013
photoreceptor cell fate specificationGO:004370410.013
response to bacteriumGO:0009617580.013
cellular response to molecule of bacterial originGO:007121930.013
regulation of cell fate specificationGO:0042659200.013
neurotransmitter transportGO:000683620.013
regulation of cysteine type endopeptidase activityGO:2000116210.013
rho protein signal transductionGO:000726650.013
membrane invaginationGO:001032410.013
regulation of mesodermal cell fate specificationGO:004266190.013
regulation of protein ubiquitinationGO:003139630.013
regulation of endopeptidase activityGO:0052548230.013
regenerationGO:0031099910.013
cellular macromolecule biosynthetic processGO:00346452240.013
lymphatic endothelial cell differentiationGO:006083610.013
phagocytosis engulfmentGO:000691110.013
regulation of dendrite morphogenesisGO:004881430.013
regulation of cell morphogenesisGO:0022604420.013
positive regulation of tyrosine phosphorylation of stat proteinGO:004253110.013
viral processGO:001603210.013
regulation of rna biosynthetic processGO:20011412130.013
regulation of inflammatory responseGO:005072720.012
cellular nitrogen compound biosynthetic processGO:00442712180.012
response to nutrientGO:000758430.012
cellular protein catabolic processGO:004425740.012
skin developmentGO:0043588540.012
modification dependent protein catabolic processGO:001994130.012

rhoub disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.193
endocrine system diseaseDOID:2800.173
musculoskeletal system diseaseDOID:1700.050
connective tissue diseaseDOID:6500.050
reproductive system diseaseDOID:1500.046
nervous system diseaseDOID:86300.041
disease of cellular proliferationDOID:1456600.028
cancerDOID:16200.028
bone diseaseDOID:008000100.025
organ system cancerDOID:005068600.023
sensory system diseaseDOID:005015500.022
bone development diseaseDOID:008000600.019
dysostosisDOID:193400.014
eye and adnexa diseaseDOID:149200.013
synostosisDOID:1197100.013