Danio rerio

0 known processes

rtkn2

rhotekin 2

(Aliases: zgc:92568,MGC113826,wu:fl63a03,sb:cb777,plekhk1)

rtkn2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular macromolecule metabolic processGO:00442603910.335
cytokinesisGO:000091030.273
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.261
cellular aromatic compound metabolic processGO:00067252950.249
macromolecule biosynthetic processGO:00090592270.222
regulation of cellular macromolecule biosynthetic processGO:20001122220.182
regulation of metabolic processGO:00192223590.179
modification dependent protein catabolic processGO:001994130.174
larval developmentGO:000216420.174
cellular nitrogen compound metabolic processGO:00346412900.160
biosynthetic processGO:00090582940.152
single organism metabolic processGO:00447102170.148
organic substance biosynthetic processGO:19015762890.147
meiotic cell cycle processGO:190304630.144
embryo development ending in birth or egg hatchingGO:00097922710.140
cellular protein catabolic processGO:004425740.139
centrosome duplicationGO:005129810.139
heterocycle metabolic processGO:00464832900.137
female meiotic divisionGO:000714320.137
spindle assemblyGO:005122520.134
positive regulation of cell cycleGO:004578730.130
agingGO:000756820.129
proteasomal protein catabolic processGO:001049820.126
regulation of gene expressionGO:00104682650.122
heterocycle biosynthetic processGO:00181302150.118
meiotic nuclear divisionGO:000712640.115
nitrogen compound metabolic processGO:00068073190.111
spindle assembly involved in mitosisGO:009030710.108
cellular macromolecule biosynthetic processGO:00346452240.108
cellular biosynthetic processGO:00442492860.105
transcription dna templatedGO:00063511810.103
nucleobase containing compound metabolic processGO:00061392740.103
ubiquitin dependent protein catabolic processGO:000651130.099
nuclear migrationGO:000709730.099
regulation of nitrogen compound metabolic processGO:00511712510.099
mitotic cell cycleGO:0000278640.098
modification dependent macromolecule catabolic processGO:004363230.097
negative regulation of cellular processGO:00485232830.096
nucleic acid metabolic processGO:00903042440.095
regulation of primary metabolic processGO:00800903110.095
cytoskeleton dependent cytokinesisGO:006164030.092
negative regulation of biological processGO:00485193040.090
negative regulation of macromolecule metabolic processGO:0010605760.089
nucleobase containing compound biosynthetic processGO:00346542050.088
organic cyclic compound metabolic processGO:19013603010.088
regulation of chromosome segregationGO:005198310.086
single organism organelle organizationGO:19025891990.083
stem cell maintenanceGO:001982740.083
regulation of rna biosynthetic processGO:20011412130.082
negative regulation of cell cycleGO:0045786140.081
mitotic dna integrity checkpointGO:004477440.081
regulation of transcription dna templatedGO:00063552130.080
mitotic g2 dna damage checkpointGO:000709530.079
regulation of macromolecule metabolic processGO:00602553170.079
negative regulation of cellular metabolic processGO:0031324770.079
cell cycleGO:0007049930.078
proteolysis involved in cellular protein catabolic processGO:005160330.078
meiotic chromosome segregationGO:004513230.076
cellular nitrogen compound biosynthetic processGO:00442712180.074
negative regulation of nuclear divisionGO:005178430.074
cell cycle arrestGO:000705010.073
regulation of rna metabolic processGO:00512522240.072
gene expressionGO:00104672520.071
regulation of nucleobase containing compound metabolic processGO:00192192500.071
regulation of protein modification by small protein conjugation or removalGO:190332030.070
g2 m transition of mitotic cell cycleGO:000008640.070
regulation of cellular biosynthetic processGO:00313262450.070
positive regulation of transportGO:005105020.070
cytokinetic processGO:003250620.069
organelle organizationGO:00069962270.068
aromatic compound biosynthetic processGO:00194382170.068
cellular component morphogenesisGO:00329893360.067
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.067
regulation of cellular metabolic processGO:00313233200.067
cell cycle processGO:0022402530.065
signal transductionGO:00071654550.063
organic cyclic compound biosynthetic processGO:19013622230.062
cellular protein metabolic processGO:00442671290.062
regulation of biosynthetic processGO:00098892500.062
regulation of meiotic cell cycleGO:005144510.062
establishment of localizationGO:00512342440.061
regulation of protein ubiquitinationGO:003139630.061
pronuclear migrationGO:003504610.061
negative regulation of mitosisGO:004583930.060
rna biosynthetic processGO:00327741810.059
rna metabolic processGO:00160702190.059
negative regulation of metabolic processGO:0009892860.058
deathGO:00162651210.058
negative regulation of cellular catabolic processGO:003133030.057
regulation of cell cycleGO:0051726520.056
g2 dna damage checkpointGO:003157230.055
mitotic cytokinesisGO:000028130.055
mitotic g2 m transition checkpointGO:004481830.053
microtubule cytoskeleton organization involved in mitosisGO:190285010.052
cellular component assemblyGO:00226071700.051
cell cycle g1 s phase transitionGO:004484310.050
protein metabolic processGO:00195381830.049
centrosome organizationGO:005129710.049
locomotionGO:00400113130.047
regulation of nucleic acid templated transcriptionGO:19035062130.047
mitotic cell cycle embryonicGO:004544820.047
cellular component movementGO:00069283350.046
regulation of response to stimulusGO:00485832690.045
organelle assemblyGO:00709251100.045
mitotic nuclear divisionGO:0007067180.044
nucleocytoplasmic transportGO:000691340.044
positive regulation of cellular processGO:00485222010.044
single organism nuclear importGO:190259330.044
microtubule organizing center organizationGO:003102310.043
phagocytosisGO:000690930.043
regulation of protein transportGO:005122330.043
protein localization to nucleusGO:003450430.042
digestive system developmentGO:00551232890.042
nucleic acid templated transcriptionGO:00976591810.042
cellular catabolic processGO:0044248270.042
establishment of protein localization to organelleGO:007259440.041
negative regulation of cell cycle phase transitionGO:190198850.041
dna metabolic processGO:0006259270.041
regulation of mitotic cell cycleGO:0007346250.041
negative regulation of macromolecule biosynthetic processGO:0010558480.041
nuclear divisionGO:0000280230.041
establishment of organelle localizationGO:0051656450.041
cytoskeleton organizationGO:0007010960.041
regulation of dna replicationGO:000627530.041
generation of neuronsGO:00486993850.040
negative regulation of cellular biosynthetic processGO:0031327550.040
negative regulation of chromosome organizationGO:200125110.039
response to external stimulusGO:00096052640.039
positive regulation of catabolic processGO:000989640.039
mitotic cell cycle processGO:1903047480.039
regulation of cell cycle processGO:0010564200.039
stem cell divisionGO:001714510.038
regulation of cell communicationGO:00106462320.037
cell divisionGO:0051301200.037
regulation of synapse organizationGO:005080730.037
stem cell fate commitmentGO:004886510.037
nuclear importGO:005117030.036
immune system processGO:00023762410.035
negative regulation of rna biosynthetic processGO:1902679450.035
oocyte maturationGO:000155640.035
response to stressGO:00069502630.034
male meiosisGO:000714020.034
phosphate containing compound metabolic processGO:00067961080.034
sensory organ developmentGO:00074233930.034
meiotic spindle organizationGO:000021210.034
neuroblast differentiationGO:001401610.034
negative regulation of biosynthetic processGO:0009890550.033
cellular component disassemblyGO:002241110.033
somatic stem cell maintenanceGO:003501910.033
cell part morphogenesisGO:00329902460.033
negative regulation of transcription dna templatedGO:0045892450.033
negative regulation of nucleobase containing compound metabolic processGO:0045934590.032
macromolecular complex assemblyGO:0065003350.032
regulation of cytoplasmic transportGO:190364940.032
transcription from rna polymerase ii promoterGO:0006366800.031
chromosome segregationGO:0007059120.031
protein import into nucleusGO:000660630.031
regulation of protein import into nucleusGO:004230620.031
g1 s transition of mitotic cell cycleGO:000008210.031
cell cycle checkpointGO:000007570.030
apoptotic processGO:00069151160.030
protein modification processGO:00362111000.030
guanosine containing compound catabolic processGO:190106920.030
negative regulation of signalingGO:0023057960.030
nuclear transportGO:005116940.030
cellular component biogenesisGO:00440851780.030
organelle localizationGO:0051640490.030
regulation of transcription from rna polymerase ii promoterGO:00063571140.030
protein complex assemblyGO:0006461300.029
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.029
cellular ketone metabolic processGO:0042180110.029
cellular amino acid metabolic processGO:000652070.029
regulation of intracellular protein transportGO:003315730.029
regulation of macromolecule biosynthetic processGO:00105562250.029
regulation of carbohydrate metabolic processGO:000610940.029
cellular response to stressGO:0033554620.029
gtp catabolic processGO:000618420.029
small molecule metabolic processGO:0044281770.028
regulation of protein catabolic processGO:004217610.028
mitotic dna damage checkpointGO:004477340.028
regulation of establishment of protein localizationGO:007020140.028
angiogenesisGO:00015251580.028
maintenance of locationGO:005123540.028
negative regulation of nucleic acid templated transcriptionGO:1903507450.028
negative regulation of protein localization to nucleusGO:190018120.028
dna biosynthetic processGO:007189730.028
negative regulation of gene expressionGO:0010629650.027
negative regulation of nucleocytoplasmic transportGO:004682320.027
protein importGO:001703830.027
regulation of nucleocytoplasmic transportGO:004682220.027
macromolecule modificationGO:00434121110.027
cell surface receptor signaling pathwayGO:00071663250.027
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.027
cell cycle g2 m phase transitionGO:004483940.027
carboxylic acid metabolic processGO:0019752220.027
regulation of cellular amine metabolic processGO:003323800.027
cellular carbohydrate metabolic processGO:004426240.027
cell proliferationGO:0008283800.026
protein polymerizationGO:005125840.026
regulation of protein targetingGO:190353320.026
response to drugGO:004249330.026
organic acid metabolic processGO:0006082310.026
neuron differentiationGO:00301823530.026
compound eye developmentGO:004874920.025
oxoacid metabolic processGO:0043436310.025
amine metabolic processGO:000930820.025
regulation of protein complex assemblyGO:004325430.025
regenerationGO:0031099910.025
centrosome cycleGO:000709810.025
protein polyubiquitinationGO:000020940.024
protein targeting to nucleusGO:004474430.024
cellular protein complex assemblyGO:0043623190.024
negative regulation of nitrogen compound metabolic processGO:0051172590.024
brain developmentGO:00074202930.024
positive regulation of cytoskeleton organizationGO:005149530.024
cell deathGO:00082191210.024
cell fate commitmentGO:0045165990.024
regulation of cell activationGO:005086510.024
embryonic organ developmentGO:00485683810.024
mitotic sister chromatid segregationGO:000007060.024
transportGO:00068102200.023
negative regulation of cell cycle processGO:001094890.023
positive regulation of nitrogen compound metabolic processGO:0051173690.023
regulation of cell differentiationGO:00455951420.023
regulation of cellular protein catabolic processGO:190336210.023
regulation of cell cycle phase transitionGO:190198780.023
regulation of cellular amino acid metabolic processGO:000652100.023
microtubule based processGO:0007017600.023
positive regulation of cellular catabolic processGO:003133130.023
negative regulation of mitotic cell cycleGO:0045930110.023
positive regulation of cellular component biogenesisGO:004408930.023
cell migrationGO:00164772370.022
cell cycle phase transitionGO:004477090.022
regulation of circadian rhythmGO:004275240.022
cellular protein modification processGO:00064641000.022
negative regulation of protein processingGO:0010955100.022
protein acetylationGO:000647320.022
positive regulation of canonical wnt signaling pathwayGO:009026340.022
negative regulation of catabolic processGO:000989530.022
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.021
programmed cell deathGO:00125011190.021
cellular amine metabolic processGO:004410620.021
catabolic processGO:0009056320.021
regulation of bindingGO:005109830.021
positive regulation of nucleoside metabolic processGO:004597910.021
neuroblast fate commitmentGO:001401710.021
organelle fissionGO:0048285230.021
eye developmentGO:00016542770.021
positive regulation of purine nucleotide catabolic processGO:003312310.021
energy reserve metabolic processGO:000611220.021
tube morphogenesisGO:00352393490.020
positive regulation of muscle organ developmentGO:004863610.020
regulation of cellular carbohydrate metabolic processGO:001067540.020
positive regulation of muscle cell differentiationGO:005114910.020
fatty acid biosynthetic processGO:000663340.020
positive regulation of cellular metabolic processGO:0031325940.020
protein dephosphorylationGO:000647030.020
regulation of signalingGO:00230512350.019
positive regulation of chromosome segregationGO:005198410.019
chromosome organization involved in meiosisGO:007019210.019
phosphorus metabolic processGO:00067931090.019
protein homooligomerizationGO:005126030.019
regulation of mitosisGO:000708890.019
vasculature developmentGO:00019442780.019
spermatid differentiationGO:004851520.019
protein complex biogenesisGO:0070271300.019
blood vessel developmentGO:00015682460.019
gtp metabolic processGO:004603940.019
female meiosis chromosome segregationGO:001632110.019
wnt signaling pathwayGO:0016055800.019
negative regulation of proteolysisGO:0045861100.019
regulation of cellular ketone metabolic processGO:001056570.018
regulation of cell projection assemblyGO:006049140.018
cellular response to chemical stimulusGO:00708871570.018
cellular response to decreased oxygen levelsGO:003629410.018
regulation of multicellular organismal developmentGO:20000262230.018
multicellular organism growthGO:003526440.018
organic substance catabolic processGO:1901575280.018
positive regulation of biological processGO:00485182530.018
regulation of protein bindingGO:004339330.018
heart developmentGO:00075073130.018
mitochondrion organizationGO:000700540.018
macromolecular complex disassemblyGO:003298410.018
intracellular signal transductionGO:0035556850.018
cellular component assembly involved in morphogenesisGO:00109271070.018
spindle assembly involved in meiosisGO:009030610.018
negative regulation of rna metabolic processGO:0051253480.018
cell projection organizationGO:00300302840.018
positive regulation of muscle tissue developmentGO:190186310.017
response to abiotic stimulusGO:00096281220.017
fertilizationGO:000956630.017
regulation of intracellular signal transductionGO:1902531570.017
microtubule cytoskeleton organizationGO:0000226330.017
regulation of catalytic activityGO:0050790550.017
macromolecular complex subunit organizationGO:0043933740.017
cilium assemblyGO:0042384580.017
cellular localizationGO:0051641970.017
antimicrobial humoral responseGO:001973020.017
regulation of cell deathGO:00109411030.017
single organism reproductive processGO:0044702400.017
chromosome organizationGO:0051276310.017
regulation of multicellular organism growthGO:004001440.017
positive regulation of dna metabolic processGO:005105410.017
internal peptidyl lysine acetylationGO:001839320.017
response to corticosteroidGO:003196010.017
negative regulation of cytoplasmic transportGO:190365020.017
liver developmentGO:0001889960.017
regulation of protein maturationGO:1903317100.016
multi organism processGO:00517041340.016
nucleic acid transportGO:005065720.016
autophagyGO:000691440.016
stem cell proliferationGO:007208940.016
regulation of mitotic cell cycle phase transitionGO:190199080.016
mitotic cell cycle phase transitionGO:004477290.016
positive regulation of cell divisionGO:005178120.016
meiosis iiGO:000713510.016
muscle structure developmentGO:00610611960.016
protein complex disassemblyGO:004324110.016
positive regulation of striated muscle tissue developmentGO:004584410.016
regulation of protein localization to nucleusGO:190018020.016
negative regulation of protein kinase activityGO:000646940.015
cellular response to hypoxiaGO:007145610.015
meiotic cell cycleGO:005132150.015
negative regulation of protein maturationGO:1903318100.015
response to glucoseGO:000974930.015
cilium morphogenesisGO:0060271850.015
somatic muscle developmentGO:000752540.015
single organism transportGO:00447652060.015
negative regulation of cell communicationGO:0010648960.015
embryonic cleavageGO:004001630.015
negative regulation of response to stimulusGO:00485851040.015
nucleus localizationGO:005164780.015
mitotic metaphase plate congressionGO:000708010.015
positive regulation of nucleobase containing compound metabolic processGO:0045935690.015
histone h4 k20 methylationGO:003477020.015
regulation of purine nucleotide catabolic processGO:003312120.015
smoothened signaling pathwayGO:0007224300.015
stem cell developmentGO:0048864820.015
muscle cell differentiationGO:00426921390.015
regulation of gtp catabolic processGO:003312420.015
cellular response to oxygen levelsGO:007145310.015
response to chemicalGO:00422213200.015
regulation of blood pressureGO:000821710.015
cleavage furrow formationGO:003608920.015
positive regulation of chromosome organizationGO:200125210.015
single organism localizationGO:19025782250.015
positive regulation of metabolic processGO:00098931080.014
tissue regenerationGO:0042246740.014
chordate embryonic developmentGO:00430092710.014
positive regulation of rna metabolic processGO:0051254590.014
regulation of organelle organizationGO:0033043290.014
central nervous system developmentGO:00074173870.014
negative regulation of intracellular signal transductionGO:1902532220.014
neuronal stem cell maintenanceGO:009715020.014
cellular macromolecular complex assemblyGO:0034622240.014
cellular response to external stimulusGO:007149620.014
histone phosphorylationGO:001657220.014
proteolysisGO:0006508380.014
negative regulation of protein phosphorylationGO:000193340.014
regulation of cell divisionGO:0051302120.014
regulation of cellular protein metabolic processGO:0032268520.014
oxidation reduction processGO:0055114410.014
membrane invaginationGO:001032410.014
regulation of skeletal muscle tissue developmentGO:004864140.014
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.014
positive regulation of macromolecule metabolic processGO:0010604930.014
positive regulation of nucleotide catabolic processGO:003081310.014
regulation of apoptotic processGO:0042981980.013
immune system developmentGO:00025201910.013
tube closureGO:006060610.013
regulation of embryonic developmentGO:0045995470.013
cellular response to extracellular stimulusGO:003166820.013
response to woundingGO:00096111160.013
b cell activationGO:004211320.013
positive regulation of rna biosynthetic processGO:1902680570.013
regulation of nucleotide catabolic processGO:003081120.013
regulation of multicellular organismal processGO:00512392770.013
cellular protein localizationGO:0034613200.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
response to monosaccharideGO:003428430.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
dna integrity checkpointGO:003157060.013
regulation of heart growthGO:006042020.013
meiosis iGO:000712710.013
response to uvGO:000941130.013
establishment of nucleus localizationGO:004002370.013
single organism biosynthetic processGO:0044711710.013
actin filament based processGO:0030029640.013
neuron developmentGO:00486662620.013
actin filament polymerizationGO:003004120.013
wound healingGO:0042060900.012
transcription elongation from rna polymerase ii promoterGO:000636830.012
germ line stem cell maintenanceGO:003071820.012
regulation of nucleoside metabolic processGO:000911820.012
reproductionGO:0000003400.012
single fertilizationGO:000733830.012
growthGO:00400071740.012
regulation of programmed cell deathGO:00430671010.012
cortical cytoskeleton organizationGO:003086510.012
ameboidal type cell migrationGO:00016671430.012
response to glucocorticoidGO:005138410.012
regulation of reactive oxygen species metabolic processGO:200037720.012
protein secretionGO:000930610.012
glial cell migrationGO:000834730.012
double strand break repairGO:000630230.012
peptidyl lysine acetylationGO:001839420.012
blood vessel morphogenesisGO:00485142160.012
cell projection morphogenesisGO:00488582440.012
negative regulation of cell divisionGO:005178240.012
regulation of reproductive processGO:200024140.012
response to organic substanceGO:00100331530.012
protein acylationGO:004354330.012
positive regulation of biosynthetic processGO:0009891680.012
germ line stem cell divisionGO:004207810.012
cell morphogenesisGO:00009022890.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
hemopoiesisGO:00300971830.012
organonitrogen compound metabolic processGO:1901564740.012
internal protein amino acid acetylationGO:000647520.012
guanosine containing compound metabolic processGO:190106840.012
proximal distal pattern formationGO:000995410.012
negative regulation of cell deathGO:0060548600.012
embryonic digestive tract developmentGO:004856640.011
digestive tract developmentGO:00485652650.011
peptidyl serine modificationGO:001820920.011
negative regulation of protein import into nucleusGO:004230820.011
morphogenesis of an epitheliumGO:00020093330.011
sister chromatid segregationGO:000081960.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
single organism cellular localizationGO:1902580460.011
regulation of cell shapeGO:000836010.011
multicellular organismal reproductive processGO:0048609350.011
negative regulation of kinase activityGO:003367340.011
positive regulation of protein complex assemblyGO:003133420.011
atp catabolic processGO:000620040.011
reproductive processGO:0022414400.011
negative regulation of apoptotic processGO:0043066550.011
regulation of cellular component organizationGO:0051128860.011
negative regulation of intracellular transportGO:003238730.011
response to hydrogen peroxideGO:004254230.011
lateral inhibitionGO:004633110.011
cell motilityGO:00488702440.011
leukocyte proliferationGO:007066110.011
regulation of proteolysisGO:0030162240.011
chromosome localizationGO:005000020.011
positive regulation of cell activationGO:005086710.011
cellular response to dna damage stimulusGO:0006974240.011
response to oxygen levelsGO:0070482250.011
phagocytosis engulfmentGO:000691110.011
determination of bilateral symmetryGO:00098552040.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
regulation of developmental processGO:00507932470.011
cellular response to reactive oxygen speciesGO:003461420.011
negative regulation of protein transportGO:005122430.011
cilium organizationGO:0044782710.011
lipid storageGO:001991510.011
protein complex subunit organizationGO:0071822460.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
nuclear envelope organizationGO:000699820.011
regulation of localizationGO:00328791040.010
regulation of molecular functionGO:0065009700.010
positive regulation of gene expressionGO:0010628710.010
negative regulation of signal transductionGO:0009968940.010
mitotic cell cycle checkpointGO:000709350.010
regulation of synaptic plasticityGO:004816710.010
regulation of epithelial to mesenchymal transitionGO:001071730.010
positive regulation of histone modificationGO:003105810.010
positive regulation of cellular carbohydrate metabolic processGO:001067610.010
cell fate specificationGO:0001708680.010
camera type eye developmentGO:00430102220.010
response to nutrientGO:000758430.010

rtkn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017
disease of anatomical entityDOID:700.013
organ system cancerDOID:005068600.011