Danio rerio

35 known processes

sae1

SUMO1 activating enzyme subunit 1

(Aliases: uble1a,sae2a,wu:fa28b04,zgc:86633)

sae1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.692
Worm
cellular aromatic compound metabolic processGO:00067252950.664
Fly
meiotic nuclear divisionGO:000712640.573
regulation of nucleobase containing compound metabolic processGO:00192192500.569
Fly
heterocycle metabolic processGO:00464832900.534
Fly
cell cycleGO:0007049930.497
Fly
nucleobase containing compound metabolic processGO:00061392740.495
Fly
nucleic acid metabolic processGO:00903042440.453
Fly
gene expressionGO:00104672520.449
Fly
cellular nitrogen compound metabolic processGO:00346412900.430
Fly
central nervous system developmentGO:00074173870.404
immune system processGO:00023762410.401
hemopoiesisGO:00300971830.377
nitrogen compound metabolic processGO:00068073190.350
Fly
single organism organelle organizationGO:19025891990.347
organelle organizationGO:00069962270.289
regulation of metabolic processGO:00192223590.283
Fly
single organism localizationGO:19025782250.261
rna metabolic processGO:00160702190.246
Fly
single organism metabolic processGO:00447102170.230
regulation of rna metabolic processGO:00512522240.215
Fly
hematopoietic or lymphoid organ developmentGO:00485341910.214
organic cyclic compound metabolic processGO:19013603010.202
Fly
rna biosynthetic processGO:00327741810.197
Fly
negative regulation of biological processGO:00485193040.181
nuclear transportGO:005116940.180
negative regulation of cellular processGO:00485232830.178
cellular nitrogen compound biosynthetic processGO:00442712180.174
Fly
nucleobase containing compound biosynthetic processGO:00346542050.167
Fly
regulation of cell cycleGO:0051726520.162
Fly
regionalizationGO:00030022740.153
positive regulation of cellular processGO:00485222010.146
regulation of mitotic cell cycleGO:0007346250.145
Fly
regulation of chromosome segregationGO:005198310.145
proteolysis involved in cellular protein catabolic processGO:005160330.144
positive regulation of biological processGO:00485182530.143
Fly
aromatic compound biosynthetic processGO:00194382170.134
Fly
mitotic dna damage checkpointGO:004477340.129
regulation of nitrogen compound metabolic processGO:00511712510.125
Fly
mitotic cell cycleGO:0000278640.116
Fly
digestive system developmentGO:00551232890.111
mitotic nuclear divisionGO:0007067180.110
nucleic acid templated transcriptionGO:00976591810.109
Fly
sensory organ developmentGO:00074233930.107
immune system developmentGO:00025201910.101
establishment of protein localization to organelleGO:007259440.098
cellular localizationGO:0051641970.098
regulation of developmental processGO:00507932470.098
regulation of nucleic acid templated transcriptionGO:19035062130.097
Fly
signal transductionGO:00071654550.097
establishment of localizationGO:00512342440.097
single organism cellular localizationGO:1902580460.097
negative regulation of cell cycle phase transitionGO:190198850.096
positive regulation of nitrogen compound metabolic processGO:0051173690.092
intracellular signal transductionGO:0035556850.092
positive regulation of macromolecule metabolic processGO:0010604930.091
organic cyclic compound biosynthetic processGO:19013622230.091
Fly
transportGO:00068102200.091
organelle fissionGO:0048285230.091
agingGO:000756820.091
response to temperature stimulusGO:0009266150.087
generation of neuronsGO:00486993850.085
cell projection organizationGO:00300302840.084
response to stressGO:00069502630.083
heart developmentGO:00075073130.083
regulation of establishment of protein localizationGO:007020140.083
determination of bilateral symmetryGO:00098552040.079
locomotionGO:00400113130.078
heterocycle biosynthetic processGO:00181302150.078
Fly
regulation of cell differentiationGO:00455951420.078
programmed cell deathGO:00125011190.076
regulation of cell proliferationGO:0042127370.074
positive regulation of nucleobase containing compound metabolic processGO:0045935690.073
regulation of cellular metabolic processGO:00313233200.069
Fly
regulation of cytoplasmic transportGO:190364940.068
positive regulation of gene expressionGO:0010628710.067
regulation of nucleocytoplasmic transportGO:004682220.067
nucleocytoplasmic transportGO:000691340.066
single organism transportGO:00447652060.066
cell proliferationGO:0008283800.065
specification of symmetryGO:00097992040.065
regulation of macromolecule biosynthetic processGO:00105562250.065
Fly
spliceosomal snrnp assemblyGO:000038720.064
cellular macromolecule metabolic processGO:00442603910.063
maintenance of locationGO:005123540.063
regulation of cellular macromolecule biosynthetic processGO:20001122220.063
Fly
protein import into nucleusGO:000660630.062
embryonic organ developmentGO:00485683810.062
neuron developmentGO:00486662620.062
negative regulation of multicellular organismal processGO:0051241690.062
mitotic dna integrity checkpointGO:004477440.061
eye developmentGO:00016542770.060
embryonic organ morphogenesisGO:00485622740.059
cell part morphogenesisGO:00329902460.059
positive regulation of cellular metabolic processGO:0031325940.058
organic substance biosynthetic processGO:19015762890.058
Fly
small molecule metabolic processGO:0044281770.057
mrna transportGO:005102820.057
apoptotic processGO:00069151160.057
cellular component assemblyGO:00226071700.056
regulation of multicellular organismal developmentGO:20000262230.056
regenerationGO:0031099910.056
cellular carbohydrate metabolic processGO:004426240.055
regulation of protein catabolic processGO:004217610.055
regulation of signalingGO:00230512350.055
cellular component biogenesisGO:00440851780.055
regulation of transcription dna templatedGO:00063552130.054
Fly
brain developmentGO:00074202930.054
positive regulation of rna metabolic processGO:0051254590.053
regulation of cellular component organizationGO:0051128860.052
liver developmentGO:0001889960.052
negative regulation of mitosisGO:004583930.052
digestive tract developmentGO:00485652650.051
tube morphogenesisGO:00352393490.051
regulation of macromolecule metabolic processGO:00602553170.050
Fly
heart morphogenesisGO:00030071560.050
neuron differentiationGO:00301823530.049
biosynthetic processGO:00090582940.049
Fly
vasculature developmentGO:00019442780.049
regulation of multicellular organismal processGO:00512392770.049
positive regulation of biosynthetic processGO:0009891680.048
regulation of programmed cell deathGO:00430671010.048
cell deathGO:00082191210.047
negative regulation of cell cycleGO:0045786140.047
cell morphogenesis involved in neuron differentiationGO:00486671630.047
response to chemicalGO:00422213200.047
muscle organ developmentGO:00075171010.046
embryonic digestive tract morphogenesisGO:004855730.045
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.045
cell morphogenesis involved in differentiationGO:00009041950.045
microtubule based processGO:0007017600.045
positive regulation of rna biosynthetic processGO:1902680570.045
regulation of signal transductionGO:00099662250.044
double strand break repairGO:000630230.044
eye morphogenesisGO:00485921440.044
cellular response to extracellular stimulusGO:003166820.043
organonitrogen compound metabolic processGO:1901564740.043
regulation of protein transportGO:005122330.043
protein localization to nucleusGO:003450430.042
symbiosis encompassing mutualism through parasitismGO:004440340.042
transcription from rna polymerase ii promoterGO:0006366800.042
negative regulation of cell deathGO:0060548600.041
recombinational repairGO:000072510.041
regulation of gene expressionGO:00104682650.041
Fly
cell cycle g1 s phase transitionGO:004484310.040
deathGO:00162651210.040
nucleoside monophosphate catabolic processGO:000912540.039
meiotic cell cycle processGO:190304630.039
regulation of nuclear divisionGO:005178390.038
protein importGO:001703830.037
amine metabolic processGO:000930820.037
regulation of gene expression epigeneticGO:0040029110.036
response to organic substanceGO:00100331530.036
intracellular transportGO:0046907320.036
organic acid metabolic processGO:0006082310.036
oxoacid metabolic processGO:0043436310.035
blood vessel developmentGO:00015682460.035
regulation of cell deathGO:00109411030.035
purine ribonucleoside monophosphate catabolic processGO:000916940.035
adult behaviorGO:003053420.034
nuclear divisionGO:0000280230.034
negative regulation of developmental processGO:0051093650.034
cellular macromolecule biosynthetic processGO:00346452240.033
Fly
developmental growthGO:00485891660.033
protein alkylationGO:0008213130.033
chromosome organizationGO:0051276310.032
proteasomal protein catabolic processGO:001049820.032
regulation of response to stimulusGO:00485832690.032
regulation of intracellular protein transportGO:003315730.032
neuron projection morphogenesisGO:00488121610.031
cellular component morphogenesisGO:00329893360.031
nucleic acid transportGO:005065720.031
response to abiotic stimulusGO:00096281220.031
protein targeting to nucleusGO:004474430.031
regulation of cell communicationGO:00106462320.030
hatchingGO:003518840.030
regulation of meiotic cell cycleGO:005144510.030
single organism nuclear importGO:190259330.030
positive regulation of nucleic acid templated transcriptionGO:1903508570.030
multi organism reproductive processGO:0044703360.030
Worm
meiosis iGO:000712710.030
system processGO:00030081850.030
organism emergence from protective structureGO:007168440.029
sensory organ morphogenesisGO:00905962000.029
negative regulation of nucleocytoplasmic transportGO:004682320.029
i kappab kinase nf kappab signalingGO:000724940.029
regulation of apoptotic processGO:0042981980.029
positive regulation of i kappab kinase nf kappab signalingGO:004312330.029
cellular response to external stimulusGO:007149620.029
regulation of cell cycle processGO:0010564200.028
cognitionGO:005089010.028
positive regulation of response to stimulusGO:0048584800.028
positive regulation of cell cycleGO:004578730.028
establishment of localization in cellGO:0051649770.028
positive regulation of macromolecule biosynthetic processGO:0010557590.028
phosphorus metabolic processGO:00067931090.028
cell cycle processGO:0022402530.027
negative regulation of cell differentiationGO:0045596460.027
phosphate containing compound metabolic processGO:00067961080.027
g1 s transition of mitotic cell cycleGO:000008210.026
regulation of intracellular signal transductionGO:1902531570.026
regulation of bindingGO:005109830.026
regulation of cellular biosynthetic processGO:00313262450.026
Fly
regulation of rna biosynthetic processGO:20011412130.026
Fly
digestive tract morphogenesisGO:00485462310.026
positive regulation of chromatin modificationGO:190331010.026
circulatory system processGO:0003013870.026
single organism intracellular transportGO:1902582250.026
angiogenesisGO:00015251580.026
carboxylic acid metabolic processGO:0019752220.025
response to heatGO:000940860.025
regulation of biosynthetic processGO:00098892500.024
Fly
protein complex subunit organizationGO:0071822460.024
cellular response to stressGO:0033554620.024
pore complex assemblyGO:004693120.024
negative regulation of intracellular transportGO:003238730.024
cytoskeleton dependent cytokinesisGO:006164030.024
regulation of cell divisionGO:0051302120.024
cellular response to chemical stimulusGO:00708871570.024
embryonic heart tube morphogenesisGO:00031431080.024
embryonic digestive tract developmentGO:004856640.024
multi organism cellular processGO:004476420.024
positive regulation of signalingGO:0023056560.023
cellular catabolic processGO:0044248270.023
non recombinational repairGO:000072620.023
mitotic cell cycle processGO:1903047480.023
regulation of multicellular organism growthGO:004001440.023
cellular amine metabolic processGO:004410620.023
regulation of transcription from rna polymerase ii promoterGO:00063571140.023
negative regulation of apoptotic processGO:0043066550.023
cellular protein localizationGO:0034613200.022
definitive hemopoiesisGO:0060216180.022
neuron projection developmentGO:00311751800.022
negative regulation of signal transductionGO:0009968940.022
transcription dna templatedGO:00063511810.022
Fly
rna export from nucleusGO:000640510.022
regulation of response to stressGO:0080134360.022
macromolecule modificationGO:00434121110.022
positive regulation of transcription dna templatedGO:0045893570.021
cell divisionGO:0051301200.021
mitotic cell cycle phase transitionGO:004477290.021
multicellular organism growthGO:003526440.021
microtubule cytoskeleton organizationGO:0000226330.021
meiotic chromosome segregationGO:004513230.021
positive regulation of metabolic processGO:00098931080.021
myeloid cell differentiationGO:0030099860.021
homeostatic processGO:00425921420.021
positive regulation of cellular biosynthetic processGO:0031328680.021
positive regulation of mrna splicing via spliceosomeGO:004802610.021
rna transportGO:005065820.021
dna metabolic processGO:0006259270.021
negative regulation of mitotic cell cycleGO:0045930110.020
establishment of rna localizationGO:005123630.020
single organism reproductive processGO:0044702400.020
Worm
ribonucleoside monophosphate catabolic processGO:000915840.020
cellular biosynthetic processGO:00442492860.020
Fly
chemosensory behaviorGO:000763510.020
cellular response to organic substanceGO:00713101050.020
regulation of glial cell differentiationGO:004568540.020
protein complex biogenesisGO:0070271300.020
cytoskeleton organizationGO:0007010960.020
regulation of dna recombinationGO:000001820.020
organic substance transportGO:0071702580.020
cellular amino acid metabolic processGO:000652070.019
macromolecule localizationGO:0033036540.019
cell projection morphogenesisGO:00488582440.019
atp catabolic processGO:000620040.019
negative regulation of response to stimulusGO:00485851040.019
macromolecular complex subunit organizationGO:0043933740.019
gland developmentGO:00487321430.019
mitotic g2 dna damage checkpointGO:000709530.019
regulation of cellular amine metabolic processGO:003323800.019
cellular protein catabolic processGO:004425740.019
cell cycle checkpointGO:000007570.018
muscle structure developmentGO:00610611960.018
protein polyubiquitinationGO:000020940.018
negative regulation of protein transportGO:005122430.018
purine nucleoside monophosphate catabolic processGO:000912840.018
positive regulation of dna metabolic processGO:005105410.018
enzyme linked receptor protein signaling pathwayGO:00071671060.018
dorsal ventral pattern formationGO:00099531250.018
cell morphogenesisGO:00009022890.018
double strand break repair via nonhomologous end joiningGO:000630310.018
cell growthGO:0016049570.018
peptidyl lysine acetylationGO:001839420.018
nuclear importGO:005117030.018
hepaticobiliary system developmentGO:0061008980.017
negative regulation of cytoplasmic transportGO:190365020.017
multicellular organismal reproductive processGO:0048609350.017
Worm
negative regulation of macromolecule metabolic processGO:0010605760.017
positive regulation of mrna processingGO:005068510.017
developmental process involved in reproductionGO:0003006270.017
Worm
positive regulation of signal transductionGO:0009967560.017
regulation of primary metabolic processGO:00800903110.017
Fly
embryonic heart tube developmentGO:00350501330.017
regulation of embryonic developmentGO:0045995470.017
negative regulation of nuclear divisionGO:005178430.017
camera type eye developmentGO:00430102220.016
lipid storageGO:001991510.016
negative regulation of ras protein signal transductionGO:004658010.016
dna integrity checkpointGO:003157060.016
microtubule organizing center organizationGO:003102310.016
regulation of biological qualityGO:00650082630.016
positive regulation of cellular catabolic processGO:003133130.016
macromolecular complex assemblyGO:0065003350.016
regulation of cellular ketone metabolic processGO:001056570.016
regulation of nervous system developmentGO:0051960900.016
regulation of protein complex assemblyGO:004325430.015
cellular ketone metabolic processGO:0042180110.015
regulation of anatomical structure morphogenesisGO:00226031300.015
modification dependent macromolecule catabolic processGO:004363230.015
single organism biosynthetic processGO:0044711710.015
ras protein signal transductionGO:000726570.015
regulation of organelle organizationGO:0033043290.015
blood vessel morphogenesisGO:00485142160.015
cell agingGO:000756920.014
positive regulation of catabolic processGO:000989640.014
heart loopingGO:0001947940.014
mitotic g2 m transition checkpointGO:004481830.014
positive regulation of glial cell differentiationGO:004568710.014
histone modificationGO:0016570200.014
positive regulation of gliogenesisGO:001401520.014
wound healingGO:0042060900.014
positive regulation of rna splicingGO:003312010.014
positive regulation of mrna metabolic processGO:190331320.014
mrna metabolic processGO:0016071200.014
negative regulation of programmed cell deathGO:0043069580.014
nucleobase containing compound transportGO:001593120.014
cell cycle g2 m phase transitionGO:004483940.014
axonogenesisGO:00074091520.014
response to lipidGO:0033993600.014
negative regulation of gene expressionGO:0010629650.014
regulation of protein targetingGO:190353320.013
multi organism processGO:00517041340.013
Worm
sexual reproductionGO:0019953360.013
Worm
regulation of mitotic cell cycle phase transitionGO:190199080.013
nuclear exportGO:005116810.013
centrosome organizationGO:005129710.013
transcription elongation from rna polymerase ii promoterGO:000636830.013
negative regulation of intracellular signal transductionGO:1902532220.013
protein localizationGO:0008104400.013
protein complex localizationGO:003150310.013
histone methylationGO:0016571130.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.013
spliceosomal tri snrnp complex assemblyGO:000024410.013
small gtpase mediated signal transductionGO:000726480.013
spermatid developmentGO:000728620.013
negative regulation of biosynthetic processGO:0009890550.013
protein acetylationGO:000647320.013
behaviorGO:0007610740.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
negative regulation of response to dna damage stimulusGO:200102130.012
mitotic cytokinesisGO:000028130.012
negative regulation of rna metabolic processGO:0051253480.012
negative regulation of cell cycle processGO:001094890.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.012
reproductionGO:0000003400.012
Worm
regulation of cellular amino acid metabolic processGO:000652100.012
camera type eye morphogenesisGO:00485931080.012
microtubule cytoskeleton organization involved in mitosisGO:190285010.012
regulation of cell developmentGO:00602841000.012
cytokinesisGO:000091030.012
catabolic processGO:0009056320.012
phagocytosisGO:000690930.012
positive regulation of cytokine productionGO:000181920.012
negative regulation of protein phosphorylationGO:000193340.012
oxidation reduction processGO:0055114410.012
neuron neuron synaptic transmissionGO:000727010.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
response to hormoneGO:0009725480.012
regulation of histone methylationGO:003106030.012
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.012
protein complex assemblyGO:0006461300.012
epithelial tube morphogenesisGO:00605621480.012
positive regulation of transportGO:005105020.012
modification of morphology or physiology of other organismGO:003582140.012
spindle assemblyGO:005122520.012
regulation of cell cycle phase transitionGO:190198780.012
glucose homeostasisGO:004259310.011
response to monosaccharideGO:003428430.011
modification dependent protein catabolic processGO:001994130.011
negative regulation of chromosome organizationGO:200125110.011
positive regulation of ras protein signal transductionGO:004657910.011
negative regulation of nucleic acid templated transcriptionGO:1903507450.011
negative regulation of nucleobase containing compound metabolic processGO:0045934590.011
negative regulation of rna biosynthetic processGO:1902679450.011
negative regulation of intracellular protein transportGO:009031730.011
meiotic cell cycleGO:005132150.011
internal peptidyl lysine acetylationGO:001839320.011
central nervous system neuron differentiationGO:0021953740.010
mitotic cell cycle checkpointGO:000709350.010
response to glucoseGO:000974930.010
growthGO:00400071740.010
chemotaxisGO:00069351040.010
double strand break repair via homologous recombinationGO:000072410.010
cellular component disassemblyGO:002241110.010
cell surface receptor signaling pathwayGO:00071663250.010
dna damage checkpointGO:000007760.010
mrna export from nucleusGO:000640610.010

sae1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.024
disease of cellular proliferationDOID:1456600.024
organ system cancerDOID:005068600.018