Danio rerio

46 known processes

scn12aa

sodium channel, voltage gated, type XII, alpha a

scn12aa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sodium ion transmembrane transportGO:0035725210.552
heart developmentGO:00075073130.476
sodium ion transportGO:0006814240.472
muscle cell developmentGO:00550011150.417
embryonic heart tube morphogenesisGO:00031431080.390
striated muscle tissue developmentGO:00147061100.381
transmembrane transportGO:00550851200.361
cardiac cell developmentGO:0055006210.331
heart morphogenesisGO:00030071560.310
muscle tissue developmentGO:00605371100.294
monovalent inorganic cation transportGO:0015672420.290
embryonic organ developmentGO:00485683810.272
cation transmembrane transportGO:0098655650.245
system processGO:00030081850.238
embryonic organ morphogenesisGO:00485622740.235
heart loopingGO:0001947940.220
heart contractionGO:0060047710.214
regulation of blood circulationGO:1903522320.211
determination of bilateral symmetryGO:00098552040.207
regulation of muscle contractionGO:000693730.199
heart processGO:0003015710.194
striated muscle cell developmentGO:00550021080.193
specification of symmetryGO:00097992040.185
determination of left right symmetryGO:00073681790.183
morphogenesis of an epitheliumGO:00020093330.179
inorganic ion transmembrane transportGO:0098660570.172
cardiac muscle tissue developmentGO:0048738480.156
neuron developmentGO:00486662620.156
muscle cell differentiationGO:00426921390.151
ion transmembrane transportGO:0034220910.144
determination of heart left right asymmetryGO:00613711170.141
regulation of heart contractionGO:0008016320.140
central nervous system developmentGO:00074173870.140
inorganic cation transmembrane transportGO:0098662500.138
regulation of ion transmembrane transportGO:0034765180.136
circulatory system processGO:0003013870.133
metal ion transportGO:0030001580.127
cardiac conductionGO:006133730.125
regulation of transmembrane transportGO:0034762180.124
embryonic heart tube developmentGO:00350501330.123
regulation of system processGO:0044057400.118
cation transportGO:0006812810.116
ion transportGO:00068111140.103
muscle structure developmentGO:00610611960.101
epithelial tube morphogenesisGO:00605621480.091
transportGO:00068102200.089
head developmentGO:00603223030.087
muscle contractionGO:0006936180.085
regulation of response to stimulusGO:00485832690.081
cell morphogenesisGO:00009022890.079
regulation of metal ion transportGO:001095940.074
striated muscle cell differentiationGO:00511461290.073
sleepGO:003043110.072
single organism localizationGO:19025782250.071
cellular component morphogenesisGO:00329893360.070
actomyosin structure organizationGO:0031032530.067
adult behaviorGO:003053420.064
tube morphogenesisGO:00352393490.064
positive regulation of transportGO:005105020.062
neuron differentiationGO:00301823530.062
single organism transportGO:00447652060.060
positive regulation of blood circulationGO:190352420.059
organelle organizationGO:00069962270.058
establishment of localizationGO:00512342440.057
regulation of biological qualityGO:00650082630.056
heterocycle metabolic processGO:00464832900.056
actin filament based movementGO:003004810.054
immune system processGO:00023762410.052
neurotransmitter transportGO:000683620.051
brain developmentGO:00074202930.051
regulation of ion transportGO:0043269220.051
cellular aromatic compound metabolic processGO:00067252950.051
positive regulation of heart contractionGO:004582320.050
regulation of ventricular cardiac muscle cell membrane repolarizationGO:006030710.049
nucleobase containing compound metabolic processGO:00061392740.049
aromatic compound biosynthetic processGO:00194382170.049
membrane repolarizationGO:008600920.048
regulation of multicellular organismal processGO:00512392770.048
multicellular organismal signalingGO:0035637220.048
cardiocyte differentiationGO:0035051440.048
regulation of transcription dna templatedGO:00063552130.048
skeletal muscle organ developmentGO:0060538780.047
atrial cardiac muscle cell developmentGO:005501440.047
ventricular cardiac muscle tissue developmentGO:000322930.045
larval developmentGO:000216420.045
ion homeostasisGO:0050801410.043
cell surface receptor signaling pathwayGO:00071663250.043
regulation of metabolic processGO:00192223590.043
calcium ion transport into cytosolGO:006040230.042
cell projection organizationGO:00300302840.042
regulation of membrane potentialGO:0042391230.041
cellular nitrogen compound biosynthetic processGO:00442712180.041
organic substance biosynthetic processGO:19015762890.040
regulation of multicellular organismal developmentGO:20000262230.040
signal transductionGO:00071654550.040
cardiac muscle cell developmentGO:0055013200.039
purine ribonucleoside monophosphate catabolic processGO:000916940.039
agingGO:000756820.038
peripheral nervous system developmentGO:0007422550.038
regulation of sequestering of calcium ionGO:005128240.037
cell projection morphogenesisGO:00488582440.037
regulation of protein bindingGO:004339330.037
regulation of developmental processGO:00507932470.036
response to stressGO:00069502630.036
blood circulationGO:0008015870.036
action potentialGO:0001508190.036
regulation of cellular macromolecule biosynthetic processGO:20001122220.036
positive regulation of cytosolic calcium ion concentrationGO:000720440.036
response to abiotic stimulusGO:00096281220.035
nucleic acid templated transcriptionGO:00976591810.035
regulation of transmembrane transporter activityGO:002289820.035
response to alkaloidGO:004327920.034
stem cell maintenanceGO:001982740.034
regulation of membrane repolarizationGO:006030610.034
cardiac muscle cell differentiationGO:0055007300.034
regulation of ion transmembrane transporter activityGO:003241220.034
nuclear transportGO:005116940.034
negative regulation of cellular processGO:00485232830.033
single organism metabolic processGO:00447102170.033
ventricular cardiac muscle tissue morphogenesisGO:005501020.033
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.033
amino acid transportGO:000686520.032
cellular nitrogen compound metabolic processGO:00346412900.032
organic acid metabolic processGO:0006082310.032
amine metabolic processGO:000930820.031
circadian sleep wake cycleGO:004274520.031
cellular biosynthetic processGO:00442492860.031
compound eye developmentGO:004874920.031
macromolecule biosynthetic processGO:00090592270.031
neuron projection developmentGO:00311751800.031
response to external stimulusGO:00096052640.031
organelle assemblyGO:00709251100.030
lipid catabolic processGO:001604240.030
positive regulation of biological processGO:00485182530.030
positive regulation of cellular catabolic processGO:003133130.030
nucleic acid metabolic processGO:00903042440.030
sequestering of calcium ionGO:005120830.030
cardiac muscle cell contractionGO:008600310.029
neurotransmitter secretionGO:000726920.029
rna localizationGO:000640340.029
transmission of nerve impulseGO:0019226190.029
cell part morphogenesisGO:00329902460.028
cytokinesisGO:000091030.028
calcium ion importGO:007050940.028
regulation of cell migration involved in sprouting angiogenesisGO:009004930.028
muscle organ developmentGO:00075171010.028
cellular macromolecule biosynthetic processGO:00346452240.027
rna metabolic processGO:00160702190.027
heterocycle biosynthetic processGO:00181302150.027
actin filament based processGO:0030029640.027
positive regulation of cell cycleGO:004578730.027
regulation of sodium ion transportGO:000202820.026
fatty acid catabolic processGO:000906210.026
cellular response to stressGO:0033554620.026
cellular response to chemical stimulusGO:00708871570.026
stem cell proliferationGO:007208940.026
divalent inorganic cation homeostasisGO:0072507220.026
regulation of sodium ion transmembrane transportGO:190230510.026
regulation of cell communicationGO:00106462320.026
regulation of nitrogen compound metabolic processGO:00511712510.026
cellular component assembly involved in morphogenesisGO:00109271070.025
neuron projection regenerationGO:0031102160.025
gene expressionGO:00104672520.025
neuron neuron synaptic transmissionGO:000727010.025
negative regulation of kinase activityGO:003367340.025
regulation of transportGO:0051049450.025
regulation of synaptic growth at neuromuscular junctionGO:000858210.025
regulation of localizationGO:00328791040.025
regulation of cell developmentGO:00602841000.024
negative regulation of sequestering of calcium ionGO:005128340.024
regulation of circadian rhythmGO:004275240.024
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.024
axonogenesisGO:00074091520.024
regulation of stem cell proliferationGO:007209120.024
regulation of jak stat cascadeGO:004642530.024
regulation of neurotransmitter transportGO:005158810.024
regulation of transporter activityGO:003240920.024
regulation of bindingGO:005109830.024
cellular component assemblyGO:00226071700.024
notch signaling pathwayGO:0007219350.024
muscle fiber developmentGO:0048747520.023
regulation of cardiac muscle cell contractionGO:008600410.023
regulation of reproductive processGO:200024140.023
regulation of signalingGO:00230512350.023
regulation of macromolecule biosynthetic processGO:00105562250.023
cardiac chamber formationGO:000320740.023
proteasomal protein catabolic processGO:001049820.023
cellular response to oxygen levelsGO:007145310.023
small molecule metabolic processGO:0044281770.023
circadian sleep wake cycle sleepGO:005080210.023
nitrogen compound metabolic processGO:00068073190.022
neuron projection morphogenesisGO:00488121610.022
regulation of signal transductionGO:00099662250.022
proteolysis involved in cellular protein catabolic processGO:005160330.022
exocytosisGO:000688710.022
startle responseGO:000196440.022
eye developmentGO:00016542770.022
sensory perception of painGO:001923310.022
negative regulation of protein kinase activityGO:000646940.022
regulation of meiotic cell cycleGO:005144510.022
stem cell fate commitmentGO:004886510.022
tissue remodelingGO:004877140.022
positive regulation of catabolic processGO:000989640.022
regulation of cellular amino acid metabolic processGO:000652100.021
cardiac conduction system developmentGO:000316110.021
actin cytoskeleton organizationGO:0030036630.021
single organism organelle organizationGO:19025891990.021
transcription dna templatedGO:00063511810.021
synaptic growth at neuromuscular junctionGO:005112420.021
notochord developmentGO:0030903540.021
organic cyclic compound metabolic processGO:19013603010.021
organic cyclic compound biosynthetic processGO:19013622230.020
cellular protein catabolic processGO:004425740.020
cell deathGO:00082191210.020
myofibril assemblyGO:0030239480.020
circadian sleep wake cycle processGO:002241020.020
vasculature developmentGO:00019442780.020
locomotionGO:00400113130.020
regenerationGO:0031099910.020
protein importGO:001703830.020
oxoacid metabolic processGO:0043436310.020
blood vessel developmentGO:00015682460.020
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.020
regulation of cellular amine metabolic processGO:003323800.020
negative regulation of secretion by cellGO:190353120.020
ventricular cardiac myofibril assemblyGO:005500540.019
regulation of tube sizeGO:003515020.019
regulation of synapse assemblyGO:005196330.019
regulation of cardiac muscle contractionGO:005511720.019
regulation of cellular biosynthetic processGO:00313262450.019
regulation of synaptic plasticityGO:004816710.019
metal ion homeostasisGO:0055065260.019
cranial nerve developmentGO:0021545420.019
positive regulation of nucleotide catabolic processGO:003081310.019
sensory organ morphogenesisGO:00905962000.018
regulation of exocytosisGO:001715710.018
organic acid catabolic processGO:001605430.018
rna biosynthetic processGO:00327741810.018
atrial cardiac myofibril assemblyGO:005500420.018
cytoskeleton organizationGO:0007010960.018
regulation of calcium ion transportGO:005192420.018
regulation of dendrite developmentGO:005077330.018
establishment of protein localization to organelleGO:007259440.018
regulation of dendrite morphogenesisGO:004881430.018
smooth muscle contractionGO:000693920.018
eye morphogenesisGO:00485921440.018
regulation of cytoplasmic transportGO:190364940.018
gtp catabolic processGO:000618420.018
regulation of apoptotic processGO:0042981980.018
small molecule catabolic processGO:004428230.017
guanosine containing compound metabolic processGO:190106840.017
regulation of neuron differentiationGO:0045664560.017
glomerulus vasculature developmentGO:007201220.017
negative regulation of cell deathGO:0060548600.017
regulation of protein complex assemblyGO:004325430.017
transcription from rna polymerase ii promoterGO:0006366800.017
regulation of neuron projection developmentGO:0010975400.017
negative regulation of protein phosphorylationGO:000193340.017
cell morphogenesis involved in differentiationGO:00009041950.017
negative regulation of reproductive processGO:200024230.017
positive regulation of cellular component biogenesisGO:004408930.017
apoptotic processGO:00069151160.017
cellular ketone metabolic processGO:0042180110.017
response to carbohydrateGO:000974330.016
sequestering of metal ionGO:005123830.016
photoreceptor cell developmentGO:0042461400.016
protein localization to nucleusGO:003450430.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
regulation of protein transportGO:005122330.016
regulation of heart rateGO:000202750.016
purine nucleoside monophosphate catabolic processGO:000912840.016
carboxylic acid metabolic processGO:0019752220.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
modification dependent macromolecule catabolic processGO:004363230.016
cellular amine metabolic processGO:004410620.016
convergent extensionGO:00600261180.016
neuroblast differentiationGO:001401610.016
regulation of gene expressionGO:00104682650.016
organonitrogen compound metabolic processGO:1901564740.015
regulation of cell deathGO:00109411030.015
regulation of protein catabolic processGO:004217610.015
outflow tract morphogenesisGO:000315110.015
regulation of macromolecule metabolic processGO:00602553170.015
kidney vasculature developmentGO:006144020.015
regulation of programmed cell deathGO:00430671010.015
immune responseGO:0006955280.015
gtp metabolic processGO:004603940.015
negative regulation of multicellular organismal processGO:0051241690.015
retina development in camera type eyeGO:00600411460.015
multicellular organism growthGO:003526440.015
positive regulation of metabolic processGO:00098931080.015
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.015
regulation of cellular metabolic processGO:00313233200.015
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.015
negative regulation of mapk cascadeGO:004340940.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
response to hexoseGO:000974630.014
regulation of primary metabolic processGO:00800903110.014
ubiquitin dependent protein catabolic processGO:000651130.014
regulation of cell differentiationGO:00455951420.014
negative regulation of stem cell differentiationGO:200073720.014
calcium ion dependent exocytosisGO:001715610.014
regulation of striated muscle contractionGO:000694220.014
cytosolic calcium ion transportGO:006040130.014
regulation of synapse organizationGO:005080730.014
positive regulation of cellular processGO:00485222010.014
erythrocyte differentiationGO:0030218540.014
endocardial cushion formationGO:000327220.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
biosynthetic processGO:00090582940.014
muscle system processGO:0003012200.014
fatty acid beta oxidationGO:000663510.014
positive regulation of nucleobase containing compound metabolic processGO:0045935690.014
multi organism processGO:00517041340.014
axon developmentGO:00615641660.014
cellular component biogenesisGO:00440851780.014
negative regulation of map kinase activityGO:004340720.014
intracellular signal transductionGO:0035556850.014
cellular ion homeostasisGO:0006873170.014
meiotic cell cycle processGO:190304630.014
actin mediated cell contractionGO:007025210.013
regulation of response to oxidative stressGO:190288220.013
cardiac myofibril assemblyGO:005500390.013
dna templated transcription initiationGO:000635210.013
cellular chemical homeostasisGO:0055082170.013
maintenance of locationGO:005123540.013
regulation of blood pressureGO:000821710.013
protein heterooligomerizationGO:005129110.013
photoreceptor cell differentiationGO:0046530550.013
regulation of cell shapeGO:000836010.013
nucleoside monophosphate catabolic processGO:000912540.013
catechol containing compound metabolic processGO:000971220.013
camera type eye morphogenesisGO:00485931080.013
regulation of neurogenesisGO:0050767870.013
membrane hyperpolarizationGO:006008110.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
response to organic substanceGO:00100331530.013
lipid storageGO:001991510.013
positive regulation of i kappab kinase nf kappab signalingGO:004312330.013
response to glucoseGO:000974930.013
endocardium morphogenesisGO:000316040.013
neuronal stem cell maintenanceGO:009715020.013
negative regulation of response to stimulusGO:00485851040.013
water homeostasisGO:003010440.013
pericardium morphogenesisGO:000334410.013
phosphate containing compound metabolic processGO:00067961080.013
cellular response to hypoxiaGO:007145610.013
developmental maturationGO:0021700340.013
negative regulation of catabolic processGO:000989530.013
cellular amino acid metabolic processGO:000652070.013
hormone secretionGO:004687920.012
mesenchyme developmentGO:00604851270.012
chemical homeostasisGO:0048878490.012
maternal determination of anterior posterior axis embryoGO:000835840.012
cardiac muscle contractionGO:006004860.012
positive regulation of gliogenesisGO:001401520.012
cortical actin cytoskeleton organizationGO:003086610.012
wnt signaling pathwayGO:0016055800.012
detection of abiotic stimulusGO:0009582240.012
locomotor rhythmGO:004547530.012
neurological system processGO:0050877620.012
negative regulation of biological processGO:00485193040.012
response to monosaccharideGO:003428430.012
cardiac atrium morphogenesisGO:000320920.012
nuclear importGO:005117030.012
regulation of nucleoside metabolic processGO:000911820.012
skeletal muscle tissue developmentGO:0007519670.012
sensory organ developmentGO:00074233930.012
eye photoreceptor cell developmentGO:0042462300.012
gamma aminobutyric acid signaling pathwayGO:000721410.012
negative regulation of apoptotic processGO:0043066550.012
regulation of blood vessel sizeGO:005088020.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
regulation of notch signaling pathwayGO:0008593160.012
somatic muscle developmentGO:000752540.012
photoreceptor cell fate commitmentGO:004655210.012
i kappab kinase nf kappab signalingGO:000724940.011
regulation of receptor activityGO:001046920.011
specification of organ positionGO:001015930.011
regulation of rna biosynthetic processGO:20011412130.011
negative regulation of metabolic processGO:0009892860.011
negative regulation of secretionGO:005104820.011
endocardial cushion morphogenesisGO:000320330.011
invagination involved in gastrulation with mouth forming secondGO:005510910.011
sex determinationGO:000753010.011
positive regulation of cellular amine metabolic processGO:003324000.011
behaviorGO:0007610740.011
carbohydrate homeostasisGO:003350010.011
protein import into nucleusGO:000660630.011
regulation of circadian sleep wake cycleGO:004274910.011
regulation of autophagyGO:001050630.011
keratinocyte differentiationGO:003021600.011
mitochondrion organizationGO:000700540.011
phosphorus metabolic processGO:00067931090.011
light absorptionGO:001603720.011
mitotic cytokinesisGO:000028130.011
negative regulation of developmental processGO:0051093650.011
regulation of protein ubiquitinationGO:003139630.011
regulation of cellular protein catabolic processGO:190336210.011
oocyte anterior posterior axis specificationGO:000731440.011
calcium ion homeostasisGO:0055074190.011
regulation of anatomical structure morphogenesisGO:00226031300.011
regulation of nucleic acid templated transcriptionGO:19035062130.011
sensory perceptionGO:0007600390.011
neuroblast proliferationGO:000740520.011
protein metabolic processGO:00195381830.011
carbohydrate biosynthetic processGO:001605110.011
negative regulation of macromolecule metabolic processGO:0010605760.011
germ line stem cell maintenanceGO:003071820.010
regulation of neurotransmitter secretionGO:004692810.010
autophagyGO:000691440.010
cytoplasm organizationGO:000702840.010
adherens junction maintenanceGO:003433420.010
photoreceptor cell fate specificationGO:004370410.010
nephron tubule morphogenesisGO:007207810.010
renal absorptionGO:007029310.010
guanosine containing compound catabolic processGO:190106920.010
regulation of epidermis developmentGO:004568220.010
eye photoreceptor cell differentiationGO:0001754450.010
neuromuscular synaptic transmissionGO:000727420.010
positive regulation of epithelial cell differentiationGO:003085820.010
appendage developmentGO:0048736800.010
positive regulation of nucleoside metabolic processGO:004597910.010
positive regulation of neural precursor cell proliferationGO:200017910.010
aorta developmentGO:003590440.010
regulation of purine nucleotide catabolic processGO:003312120.010
regulation of cellular response to oxidative stressGO:190040720.010
regulation of cytokine productionGO:000181730.010
cytoskeleton dependent cytokinesisGO:006164030.010
ribonucleoside monophosphate catabolic processGO:000915840.010
stem cell divisionGO:001714510.010
glial cell proliferationGO:001400940.010
regulation of neural precursor cell proliferationGO:200017730.010
cellular cation homeostasisGO:0030003170.010
mesenchymal cell proliferationGO:001046310.010
glial cell migrationGO:000834730.010
regulation of oxidative stress induced cell deathGO:190320120.010
nephric duct developmentGO:0072176130.010
response to light stimulusGO:0009416460.010

scn12aa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.068
cardiovascular system diseaseDOID:128700.057
heart diseaseDOID:11400.033
cardiomyopathyDOID:005070000.033
muscular diseaseDOID:008000000.033
musculoskeletal system diseaseDOID:1700.033
myopathyDOID:42300.033
muscle tissue diseaseDOID:6600.033
nervous system diseaseDOID:86300.023
disease of metabolismDOID:001466700.012
immune system diseaseDOID:291400.010