Danio rerio

75 known processes

scn8aa

sodium channel, voltage-gated, type VIII, alpha a

(Aliases: scn8a,Nav1.6)

scn8aa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cognitionGO:005089010.940
neuron projection morphogenesisGO:00488121610.935
larval developmentGO:000216420.916
cellular component morphogenesisGO:00329893360.908
axon developmentGO:00615641660.892
cation transmembrane transportGO:0098655650.883
generation of neuronsGO:00486993850.857
neuron differentiationGO:00301823530.836
cell morphogenesis involved in differentiationGO:00009041950.792
neuron projection guidanceGO:0097485860.789
transmembrane transportGO:00550851200.787
single organism behaviorGO:0044708240.753
response to axon injuryGO:0048678140.745
regulation of gene expressionGO:00104682650.699
neuron projection regenerationGO:0031102160.659
neuron developmentGO:00486662620.642
sensory organ developmentGO:00074233930.628
regulation of developmental processGO:00507932470.626
cell morphogenesis involved in neuron differentiationGO:00486671630.615
regulation of macromolecule metabolic processGO:00602553170.602
cell projection organizationGO:00300302840.597
taxisGO:00423301090.595
synaptic transmissionGO:0007268350.593
axonogenesisGO:00074091520.585
ion transmembrane transportGO:0034220910.571
system processGO:00030081850.520
Zebrafish Mouse
response to abiotic stimulusGO:00096281220.520
head developmentGO:00603223030.515
neurological system processGO:0050877620.493
Zebrafish Mouse
response to external stimulusGO:00096052640.489
central nervous system neuron differentiationGO:0021953740.485
cellular biosynthetic processGO:00442492860.480
cellular nitrogen compound metabolic processGO:00346412900.471
neural retina developmentGO:0003407490.467
cellular component assemblyGO:00226071700.464
sensory organ morphogenesisGO:00905962000.447
vasculature developmentGO:00019442780.436
central nervous system developmentGO:00074173870.434
mechanosensory behaviorGO:000763820.428
neuron neuron synaptic transmissionGO:000727010.424
response to mechanical stimulusGO:0009612240.415
synaptic growth at neuromuscular junctionGO:005112420.414
behaviorGO:0007610740.410
locomotionGO:00400113130.401
regulation of synaptic plasticityGO:004816710.392
eye developmentGO:00016542770.390
establishment of localizationGO:00512342440.387
single organism transportGO:00447652060.364
transmission of nerve impulseGO:0019226190.354
Zebrafish
eye morphogenesisGO:00485921440.348
cell morphogenesisGO:00009022890.345
regulation of multicellular organismal processGO:00512392770.343
single organism localizationGO:19025782250.335
response to drugGO:004249330.334
establishment of blood brain barrierGO:006085620.333
negative regulation of multicellular organismal processGO:0051241690.324
regulation of cellular macromolecule biosynthetic processGO:20001122220.322
positive regulation of cellular processGO:00485222010.320
regulation of biological qualityGO:00650082630.318
Zebrafish
nucleobase containing compound metabolic processGO:00061392740.316
transportGO:00068102200.312
cellular aromatic compound metabolic processGO:00067252950.308
muscle structure developmentGO:00610611960.306
Mouse
anterior lateral line system developmentGO:004889890.305
regulation of cellular metabolic processGO:00313233200.301
heterocycle metabolic processGO:00464832900.291
nitrogen compound metabolic processGO:00068073190.276
synaptic vesicle transportGO:004848910.269
embryonic organ developmentGO:00485683810.267
homeostatic processGO:00425921420.260
polarized epithelial cell differentiationGO:003085940.258
gene expressionGO:00104672520.257
hair cell differentiationGO:0035315320.255
nucleic acid metabolic processGO:00903042440.254
cellular component biogenesisGO:00440851780.253
organonitrogen compound metabolic processGO:1901564740.242
neuron projection developmentGO:00311751800.239
nitrogen compound transportGO:0071705230.238
cell growthGO:0016049570.238
blood vessel morphogenesisGO:00485142160.235
camera type eye developmentGO:00430102220.234
neuromuscular synaptic transmissionGO:000727420.234
embryonic organ morphogenesisGO:00485622740.231
cell part morphogenesisGO:00329902460.230
rna biosynthetic processGO:00327741810.225
cellular macromolecule biosynthetic processGO:00346452240.222
cellular macromolecule metabolic processGO:00442603910.221
establishment of synaptic vesicle localizationGO:009748010.215
response to woundingGO:00096111160.215
synapse assemblyGO:000741690.211
regulation of cellular biosynthetic processGO:00313262450.210
heart developmentGO:00075073130.209
protein metabolic processGO:00195381830.203
regulation of membrane potentialGO:0042391230.200
Zebrafish
response to stressGO:00069502630.199
muscle cell differentiationGO:00426921390.193
peripheral nervous system developmentGO:0007422550.192
positive regulation of nervous system developmentGO:0051962250.191
regulation of multicellular organismal developmentGO:20000262230.190
neuronal ion channel clusteringGO:004516140.188
immune system developmentGO:00025201910.185
blood vessel developmentGO:00015682460.183
anterior lateral line nerve glial cell differentiationGO:004891330.182
regulation of cell differentiationGO:00455951420.177
developmental growthGO:00485891660.177
rna metabolic processGO:00160702190.175
regulation of neuron differentiationGO:0045664560.175
regulation of neuron projection developmentGO:0010975400.174
macromolecule biosynthetic processGO:00090592270.174
nerve developmentGO:0021675450.174
axon regenerationGO:0031103140.173
regulation of rna metabolic processGO:00512522240.169
regulation of axonogenesisGO:0050770320.168
anterior lateral line nerve glial cell morphogenesis involved in differentiationGO:004894030.162
inorganic cation transmembrane transportGO:0098662500.161
epithelial cell differentiationGO:00308551160.160
anterior lateral line nerve glial cell developmentGO:004893930.158
organic substance biosynthetic processGO:19015762890.156
growthGO:00400071740.155
myelination of lateral line nerve axonsGO:004889750.154
establishment of vesicle localizationGO:0051650240.151
biosynthetic processGO:00090582940.151
regulation of signalingGO:00230512350.150
germ line stem cell maintenanceGO:003071820.150
regulation of synapse assemblyGO:005196330.148
camera type eye morphogenesisGO:00485931080.147
sensory perception of mechanical stimulusGO:0050954160.147
Mouse
positive regulation of transportGO:005105020.146
myelination of anterior lateral line nerve axonsGO:004891430.144
regulation of nucleobase containing compound metabolic processGO:00192192500.141
motor neuron axon guidanceGO:0008045230.141
axon extensionGO:0048675450.138
establishment of localization in cellGO:0051649770.135
regulation of primary metabolic processGO:00800903110.131
posterior lateral line nerve developmentGO:004891880.129
cellular protein metabolic processGO:00442671290.127
l amino acid transportGO:001580710.124
chemotaxisGO:00069351040.124
inorganic ion transmembrane transportGO:0098660570.122
negative regulation of cell differentiationGO:0045596460.122
regulation of transcription dna templatedGO:00063552130.121
hemopoiesisGO:00300971830.121
reflexGO:006000420.120
regulation of dendrite developmentGO:005077330.120
positive regulation of biological processGO:00485182530.119
negative regulation of developmental processGO:0051093650.118
determination of bilateral symmetryGO:00098552040.118
embryonic skeletal system morphogenesisGO:0048704930.118
small molecule metabolic processGO:0044281770.118
chordate embryonic developmentGO:00430092710.117
synaptic transmission cholinergicGO:000727140.115
microtubule based processGO:0007017600.115
forebrain developmentGO:0030900960.114
posterior lateral line nerve glial cell developmentGO:004894150.114
organic acid metabolic processGO:0006082310.109
regulation of nervous system developmentGO:0051960900.108
vesicle localizationGO:0051648270.108
regenerationGO:0031099910.107
regulation of hormone secretionGO:004688320.106
adult behaviorGO:003053420.105
Mouse
cellular component movementGO:00069283350.103
response to chemicalGO:00422213200.102
retina development in camera type eyeGO:00600411460.102
regulation of synaptic growth at neuromuscular junctionGO:000858210.101
exocytosisGO:000688710.100
amino acid transportGO:000686520.099
single organism membrane fusionGO:004480120.098
multi organism processGO:00517041340.097
neurotransmitter transportGO:000683620.095
regulation of anatomical structure morphogenesisGO:00226031300.095
positive regulation of developmental processGO:0051094500.093
oxoacid metabolic processGO:0043436310.091
regulation of axon extensionGO:0030516240.090
larval behaviorGO:003053750.089
axon guidanceGO:0007411860.089
organelle organizationGO:00069962270.088
specification of symmetryGO:00097992040.087
cellular localizationGO:0051641970.087
regulation of metabolic processGO:00192223590.086
digestive tract developmentGO:00485652650.085
neuromast developmentGO:0048884460.084
striated muscle cell differentiationGO:00511461290.083
neuromuscular process controlling balanceGO:005088530.082
regulation of cellular component organizationGO:0051128860.081
regulation of synapse structure and activityGO:005080350.081
heart morphogenesisGO:00030071560.081
anterior lateral line nerve developmentGO:004890940.080
cell cell signalingGO:0007267520.080
central nervous system neuron axonogenesisGO:0021955180.079
regulation of response to stimulusGO:00485832690.078
brain developmentGO:00074202930.078
cell surface receptor signaling pathwayGO:00071663250.078
embryonic cranial skeleton morphogenesisGO:0048701900.077
cation transportGO:0006812810.077
hormone transportGO:000991420.076
retinal cell programmed cell deathGO:004666620.076
regulation of neurogenesisGO:0050767870.076
regulation of rna biosynthetic processGO:20011412130.076
embryonic heart tube morphogenesisGO:00031431080.075
cellular amino acid metabolic processGO:000652070.075
inner ear developmentGO:00488391260.075
synapse organizationGO:0050808210.074
cellular nitrogen compound biosynthetic processGO:00442712180.073
organic cyclic compound biosynthetic processGO:19013622230.073
neuronal action potentialGO:0019228180.072
Zebrafish
innervationGO:006038430.072
single organism metabolic processGO:00447102170.072
muscle organ developmentGO:00075171010.071
Mouse
retina morphogenesis in camera type eyeGO:0060042790.071
ear developmentGO:00435831270.070
taurine metabolic processGO:001953010.069
tube morphogenesisGO:00352393490.069
regulation of signal transductionGO:00099662250.068
action potentialGO:0001508190.068
Zebrafish
synaptic vesicle localizationGO:009747910.068
pigmentationGO:0043473850.067
membrane repolarizationGO:008600920.066
circulatory system processGO:0003013870.064
heterocycle biosynthetic processGO:00181302150.064
receptor recyclingGO:000188140.063
appendage developmentGO:0048736800.063
signal transductionGO:00071654550.062
positive regulation of neuron differentiationGO:0045666120.062
neuromuscular junction developmentGO:000752890.062
transcription from rna polymerase ii promoterGO:0006366800.062
response to alkaloidGO:004327920.061
angiogenesisGO:00015251580.061
developmental growth involved in morphogenesisGO:0060560860.059
organic cyclic compound metabolic processGO:19013603010.057
cell projection morphogenesisGO:00488582440.056
endocardium developmentGO:000315790.055
negative regulation of gene expressionGO:0010629650.055
negative regulation of neurogenesisGO:0050768200.054
mechanoreceptor differentiationGO:0042490370.053
lateral line nerve glial cell developmentGO:004893760.053
regulation of synapse organizationGO:005080730.052
protein complex assemblyGO:0006461300.052
neuron projection extensionGO:1990138450.052
hematopoietic or lymphoid organ developmentGO:00485341910.051
single organism membrane organizationGO:0044802200.051
regulation of multicellular organism growthGO:004001440.049
regulation of nucleic acid templated transcriptionGO:19035062130.049
regulation of cellular component sizeGO:0032535300.049
negative regulation of cellular processGO:00485232830.048
peripheral nervous system neuron differentiationGO:0048934280.048
regulation of growthGO:0040008420.048
enzyme linked receptor protein signaling pathwayGO:00071671060.048
ear morphogenesisGO:0042471640.047
neuron fate commitmentGO:0048663260.047
macromolecular complex disassemblyGO:003298410.047
positive regulation of neural precursor cell proliferationGO:200017910.047
organic anion transportGO:0015711150.046
inner ear morphogenesisGO:0042472630.046
myelination of posterior lateral line nerve axonsGO:004893250.045
neural tube developmentGO:0021915620.045
regulation of neuronal synaptic plasticityGO:004816810.045
monocarboxylic acid biosynthetic processGO:0072330120.044
regulation of transmembrane transportGO:0034762180.044
cranial nerve developmentGO:0021545420.044
sensory perception of chemical stimulusGO:000760630.044
neurotransmitter secretionGO:000726920.043
morphogenesis of an epitheliumGO:00020093330.042
metal ion transportGO:0030001580.041
aromatic compound biosynthetic processGO:00194382170.040
cell proliferationGO:0008283800.040
alpha amino acid metabolic processGO:190160530.040
positive regulation of synapse assemblyGO:005196510.040
neural crest cell developmentGO:0014032620.040
positive regulation of cell communicationGO:0010647560.040
regulation of protein metabolic processGO:0051246560.040
chemosensory behaviorGO:000763510.039
carboxylic acid metabolic processGO:0019752220.038
stem cell differentiationGO:00488631170.038
cellular amine metabolic processGO:004410620.038
positive regulation of signalingGO:0023056560.037
skeletal system morphogenesisGO:00487051020.037
sensory system developmentGO:0048880760.037
axon cargo transportGO:000808820.037
neuron projection extension involved in neuron projection guidanceGO:1902284100.037
cellular component disassemblyGO:002241110.037
multicellular organismal signalingGO:0035637220.037
Zebrafish
anterior lateral line developmentGO:004889950.035
organelle localizationGO:0051640490.035
cellular response to stressGO:0033554620.035
cell deathGO:00082191210.035
nucleobase containing compound biosynthetic processGO:00346542050.034
positive regulation of neurogenesisGO:0050769240.034
negative regulation of response to stimulusGO:00485851040.034
regulation of cell projection organizationGO:0031344440.033
synaptic vesicle recyclingGO:003646510.033
regulation of cell morphogenesisGO:0022604420.033
axonal fasciculationGO:0007413110.033
pigment granule localizationGO:0051875250.033
regulation of cell developmentGO:00602841000.033
membrane organizationGO:0061024210.033
determination of left right symmetryGO:00073681790.032
neuromast hair cell differentiationGO:0048886120.032
posterior lateral line nerve glial cell morphogenesis involved in differentiationGO:004894250.032
ion transportGO:00068111140.032
positive regulation of cell cycleGO:004578730.032
multicellular organismal reproductive processGO:0048609350.032
positive regulation of neuron projection developmentGO:001097690.032
response to organic substanceGO:00100331530.031
response to light stimulusGO:0009416460.031
spinal cord motor neuron differentiationGO:0021522260.031
regulation of cell morphogenesis involved in differentiationGO:0010769380.030
posterior lateral line system developmentGO:0048915460.030
central nervous system neuron developmentGO:0021954290.030
gland developmentGO:00487321430.030
skeletal system developmentGO:00015011810.030
gtp metabolic processGO:004603940.030
posterior lateral line nerve glial cell differentiationGO:004893150.029
regulation of transcription from rna polymerase ii promoterGO:00063571140.029
hormone secretionGO:004687920.028
heart contractionGO:0060047710.028
multi organism reproductive processGO:0044703360.028
regulation of neural precursor cell proliferationGO:200017730.028
neuroblast proliferationGO:000740520.028
biological adhesionGO:0022610400.028
phagocytosisGO:000690930.028
axis specificationGO:0009798430.027
chemical homeostasisGO:0048878490.027
positive regulation of cell differentiationGO:0045597300.027
amine metabolic processGO:000930820.027
developmental pigmentationGO:0048066480.027
negative regulation of biological processGO:00485193040.026
positive regulation of neuron deathGO:190121610.026
positive regulation of catabolic processGO:000989640.026
regulation of cell communicationGO:00106462320.026
divalent inorganic cation homeostasisGO:0072507220.026
regulation of dendrite morphogenesisGO:004881430.026
positive regulation of response to stimulusGO:0048584800.026
regulation of localizationGO:00328791040.025
negative regulation of nitrogen compound metabolic processGO:0051172590.025
lateral line nerve developmentGO:004889290.025
erythrocyte differentiationGO:0030218540.025
regulation of system processGO:0044057400.025
endothelial cell migrationGO:0043542190.025
positive regulation of secretion by cellGO:190353210.025
urogenital system developmentGO:0001655970.025
posterior lateral line neuromast hair cell differentiationGO:004892380.025
ensheathment of neuronsGO:0007272180.025
columnar cuboidal epithelial cell differentiationGO:0002065380.024
regulation of peptidyl tyrosine phosphorylationGO:005073010.024
blood circulationGO:0008015870.024
venous endothelial cell migration involved in lymph vessel developmentGO:006085540.024
muscle system processGO:0003012200.024
mesenchyme developmentGO:00604851270.023
locomotory behaviorGO:0007626340.023
positive regulation of secretionGO:005104710.023
lateral line nerve glial cell morphogenesis involved in differentiationGO:004893850.023
regulation of neuron migrationGO:200122220.023
regulation of neurological system processGO:003164420.023
transcription dna templatedGO:00063511810.023
endocytosisGO:0006897160.023
locomotor rhythmGO:004547530.023
heart processGO:0003015710.023
monovalent inorganic cation transportGO:0015672420.022
determination of heart left right asymmetryGO:00613711170.022
rna localizationGO:000640340.022
negative regulation of nucleobase containing compound metabolic processGO:0045934590.022
cell adhesionGO:0007155400.022
otolith developmentGO:0048840320.022
sensory perceptionGO:0007600390.022
Mouse
negative regulation of cell deathGO:0060548600.022
regulation of response to external stimulusGO:0032101310.022
telencephalon developmentGO:0021537140.022
establishment of organelle localizationGO:0051656450.022
regulation of inhibitory postsynaptic membrane potentialGO:006008010.022
inositol lipid mediated signalingGO:004801720.021
regulation of nitrogen compound metabolic processGO:00511712510.021
mechanosensory lateral line system developmentGO:0048881490.021
macromolecular complex assemblyGO:0065003350.021
regulation of cellular amine metabolic processGO:003323800.021
regulation of developmental growthGO:0048638380.021
cellular homeostasisGO:0019725260.021
microtubule based movementGO:0007018330.021
regulation of cell growthGO:0001558290.020
cell adhesion mediated by integrinGO:003362710.020
posterior lateral line neuromast developmentGO:0048919200.020
regulation of mrna splicing via spliceosomeGO:004802430.020
segmentationGO:0035282970.020
regulation of axon extension involved in axon guidanceGO:004884160.020
protein oligomerizationGO:005125970.020
protein complex disassemblyGO:004324110.020
regulation of postsynaptic membrane potentialGO:006007810.020
renal system developmentGO:0072001940.020
regionalizationGO:00030022740.020
regulation of cellular ketone metabolic processGO:001056570.020
muscle tissue developmentGO:00605371100.019
response to radiationGO:0009314510.019
multicellular organism growthGO:003526440.019
multicellular organism reproductionGO:0032504350.019
melanosome transportGO:0032402190.019
actin cytoskeleton organizationGO:0030036630.019
semicircular canal morphogenesisGO:0048752180.019
regulation of protein complex disassemblyGO:004324410.019
lateral line developmentGO:0048882660.019
intracellular signal transductionGO:0035556850.019
calcium mediated signalingGO:001972220.019
detection of stimulusGO:0051606290.019
negative regulation of cell adhesionGO:000716260.019
regulation of macromolecule biosynthetic processGO:00105562250.018
regulation of cellular amino acid metabolic processGO:000652100.018
catechol containing compound biosynthetic processGO:000971320.018
membrane fusionGO:006102520.018
compound eye developmentGO:004874920.018
spinal cord developmentGO:0021510460.018
regulation of cell cycleGO:0051726520.018
myeloid cell developmentGO:0061515320.018
lateral line system developmentGO:0048925760.018
organelle assemblyGO:00709251100.018
rna processingGO:0006396250.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.018
endocardium formationGO:006021410.018
fertilizationGO:000956630.018
pronephric nephron developmentGO:0039019140.017
regulation of transportGO:0051049450.017
regulation of tyrosine phosphorylation of stat proteinGO:004250910.017
positive regulation of multicellular organismal processGO:0051240520.017
regulation of synaptic transmissionGO:005080440.017
regulation of cell adhesionGO:0030155150.017
establishment of cell polarityGO:0030010180.017
cellular protein modification processGO:00064641000.017
metencephalon developmentGO:0022037270.017
regulation of neural retina developmentGO:006107420.017
nucleic acid templated transcriptionGO:00976591810.017
diencephalon developmentGO:0021536580.017
cell motilityGO:00488702440.017
signal transduction in absence of ligandGO:003803410.016
phosphorylationGO:0016310690.016
regulation of extent of cell growthGO:0061387290.016
negative regulation of cellular metabolic processGO:0031324770.016
specification of axis polarityGO:006500140.016
isoprenoid catabolic processGO:000830020.016
phosphorus metabolic processGO:00067931090.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.016
negative regulation of rna metabolic processGO:0051253480.016
catecholamine biosynthetic processGO:004242320.016
positive regulation of cell divisionGO:005178120.016
synaptic transmission glycinergicGO:006001210.015
regulation of ion transportGO:0043269220.015
locus ceruleus developmentGO:002170330.015
cell cycleGO:0007049930.015
cardiogenic plate morphogenesisGO:000314210.015
positive regulation of cell developmentGO:0010720250.015
maintenance of locationGO:005123540.015
regulation of intracellular signal transductionGO:1902531570.015
negative regulation of nervous system developmentGO:0051961220.015
neuroblast fate commitmentGO:001401710.015
negative regulation of metabolic processGO:0009892860.015
cell divisionGO:0051301200.015
response to monosaccharideGO:003428430.015
regulation of programmed cell deathGO:00430671010.015
muscle cell developmentGO:00550011150.015
proteolysis involved in cellular protein catabolic processGO:005160330.015
long chain fatty acid biosynthetic processGO:004275910.015
reproductive processGO:0022414400.015
cellular response to oxygen containing compoundGO:1901701200.015
cytoskeleton organizationGO:0007010960.015
membrane hyperpolarizationGO:006008110.014
regulation of cell sizeGO:0008361290.014
peptide transportGO:001583310.014
developmental cell growthGO:0048588520.014
positive regulation of cellular catabolic processGO:003133130.014
peripheral nervous system neuron developmentGO:0048935220.014
central nervous system projection neuron axonogenesisGO:0021952150.014
regulation of calcium mediated signalingGO:005084810.014
regulation of biosynthetic processGO:00098892500.014
eye photoreceptor cell developmentGO:0042462300.014
meiotic nuclear divisionGO:000712640.014
inner ear receptor cell developmentGO:0060119200.014
cellular ketone metabolic processGO:0042180110.014
detection of abiotic stimulusGO:0009582240.014
apoptotic processGO:00069151160.014
semicircular canal developmentGO:0060872240.013
response to oxygen containing compoundGO:1901700550.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.013
response to hexoseGO:000974630.013
regulation of ion transmembrane transporter activityGO:003241220.013
cell recognitionGO:0008037190.013
regulation of cell shapeGO:000836010.013
carbohydrate homeostasisGO:003350010.013
small molecule catabolic processGO:004428230.013
gabaergic neuron differentiationGO:009715420.013
organic substance transportGO:0071702580.013
determination of intestine left right asymmetryGO:007190820.013
organism emergence from protective structureGO:007168440.013
atp catabolic processGO:000620040.013
primitive hemopoiesisGO:0060215270.013
agingGO:000756820.013

scn8aa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.092
nervous system diseaseDOID:86300.022
organ system cancerDOID:005068600.015
cancerDOID:16200.015
endocrine gland cancerDOID:17000.015
disease of cellular proliferationDOID:1456600.015