Danio rerio

38 known processes

spint1a

serine peptidase inhibitor, Kunitz type 1 a

(Aliases: cb376,sb:cb376,spint1l,zgc:64075)

spint1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of transcription dna templatedGO:00063552130.643
skeletal system developmentGO:00015011810.539
hemopoiesisGO:00300971830.538
sensory system developmentGO:0048880760.505
regulation of cellular biosynthetic processGO:00313262450.482
lateral line system developmentGO:0048925760.480
lateral line developmentGO:0048882660.471
cellular component movementGO:00069283350.464
immune system developmentGO:00025201910.414
biological adhesionGO:0022610400.413
posterior lateral line system developmentGO:0048915460.390
sensory organ developmentGO:00074233930.367
biosynthetic processGO:00090582940.329
stem cell divisionGO:001714510.323
skin developmentGO:0043588540.304
mechanosensory lateral line system developmentGO:0048881490.285
inner ear developmentGO:00488391260.282
generation of neuronsGO:00486993850.276
cellular component biogenesisGO:00440851780.256
transcription dna templatedGO:00063511810.243
renal system developmentGO:0072001940.234
rna biosynthetic processGO:00327741810.231
digestive tract developmentGO:00485652650.229
nucleic acid templated transcriptionGO:00976591810.221
fin morphogenesisGO:0033334530.209
nucleobase containing compound biosynthetic processGO:00346542050.207
morphogenesis of an epitheliumGO:00020093330.200
Mouse
ear developmentGO:00435831270.197
cilium morphogenesisGO:0060271850.195
macromolecular complex subunit organizationGO:0043933740.190
embryonic organ morphogenesisGO:00485622740.183
aromatic compound biosynthetic processGO:00194382170.169
medial fin developmentGO:0033338160.164
kidney developmentGO:0001822920.162
single organism cell adhesionGO:0098602290.160
negative regulation of cellular processGO:00485232830.159
epithelial cell developmentGO:0002064420.158
organic cyclic compound biosynthetic processGO:19013622230.154
digestive system developmentGO:00551232890.152
epithelial cell differentiationGO:00308551160.146
cell motilityGO:00488702440.145
regulation of macromolecule biosynthetic processGO:00105562250.145
nucleic acid metabolic processGO:00903042440.145
regulation of rna metabolic processGO:00512522240.142
single organism localizationGO:19025782250.142
regulation of macromolecule metabolic processGO:00602553170.136
establishment of endothelial barrierGO:006102830.135
establishment of protein localization to plasma membraneGO:009000210.135
negative regulation of response to stimulusGO:00485851040.134
appendage morphogenesisGO:0035107560.131
hematopoietic or lymphoid organ developmentGO:00485341910.130
rna metabolic processGO:00160702190.129
regulation of nucleic acid templated transcriptionGO:19035062130.128
cellular macromolecule metabolic processGO:00442603910.127
medial fin morphogenesisGO:0035141140.125
regulation of cellular macromolecule biosynthetic processGO:20001122220.124
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.121
alcohol biosynthetic processGO:004616520.116
single organismal cell cell adhesionGO:0016337290.115
heart developmentGO:00075073130.115
cell adhesionGO:0007155400.113
modification dependent protein catabolic processGO:001994130.112
cellular macromolecule biosynthetic processGO:00346452240.112
angiogenesisGO:00015251580.112
cell proliferationGO:0008283800.110
organic substance biosynthetic processGO:19015762890.109
regulation of nitrogen compound metabolic processGO:00511712510.109
digestive tract morphogenesisGO:00485462310.109
cell projection morphogenesisGO:00488582440.109
single organism organelle organizationGO:19025891990.108
epibolyGO:0090504410.107
regulation of rna biosynthetic processGO:20011412130.107
regulation of primary metabolic processGO:00800903110.105
cell cell adhesion involved in gastrulationGO:007058640.103
embryonic organ developmentGO:00485683810.102
Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.099
organelle organizationGO:00069962270.099
regulation of eye photoreceptor cell developmentGO:004247820.099
regulation of gene expressionGO:00104682650.098
extracellular structure organizationGO:0043062270.096
Mouse
cell surface receptor signaling pathwayGO:00071663250.096
vasculature developmentGO:00019442780.095
Mouse
cellular component morphogenesisGO:00329893360.095
extracellular matrix organizationGO:0030198270.095
Mouse
cellular nitrogen compound metabolic processGO:00346412900.094
muscle tissue developmentGO:00605371100.092
regulation of biological qualityGO:00650082630.092
desmosome assemblyGO:000215920.091
urogenital system developmentGO:0001655970.091
regulation of response to stressGO:0080134360.090
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.086
nucleobase containing compound metabolic processGO:00061392740.085
gastrulationGO:00073692080.085
gastrulation with mouth forming secondGO:0001702440.084
head developmentGO:00603223030.084
single organism metabolic processGO:00447102170.084
meiotic nuclear divisionGO:000712640.083
localization of cellGO:00516742440.082
notch signaling pathwayGO:0007219350.081
regulation of cellular metabolic processGO:00313233200.079
eye morphogenesisGO:00485921440.078
cell cell adhesion involved in mesendodermal cell migrationGO:000337010.078
neuron differentiationGO:00301823530.077
negative regulation of wnt signaling pathway involved in heart developmentGO:000330820.075
protein localization to plasma membraneGO:007265910.075
blood vessel morphogenesisGO:00485142160.075
organic cyclic compound metabolic processGO:19013603010.075
eye developmentGO:00016542770.074
fin developmentGO:0033333770.074
endothelial cell developmentGO:0001885120.074
negative regulation of signal transductionGO:0009968940.074
cell migrationGO:00164772370.073
convergent extensionGO:00600261180.071
neuroblast differentiationGO:001401610.071
negative regulation of biological processGO:00485193040.069
positive regulation of biological processGO:00485182530.068
nuclear transportGO:005116940.068
stem cell proliferationGO:007208940.067
appendage developmentGO:0048736800.067
heterocycle metabolic processGO:00464832900.065
establishment of cell polarity involved in ameboidal cell migrationGO:000336520.064
positive regulation of transcription dna templatedGO:0045893570.064
gland developmentGO:00487321430.063
regulation of nucleocytoplasmic transportGO:004682220.063
negative regulation of epithelial cell proliferationGO:005068010.063
protein metabolic processGO:00195381830.060
intestinal epithelial cell differentiationGO:006057530.060
establishment of protein localization to organelleGO:007259440.059
brain developmentGO:00074202930.059
proximal distal pattern formationGO:000995410.058
stem cell maintenanceGO:001982740.058
neuromast developmentGO:0048884460.057
gene expressionGO:00104672520.057
response to abiotic stimulusGO:00096281220.057
growthGO:00400071740.056
regulation of stem cell differentiationGO:200073640.056
regulation of epithelial cell proliferationGO:005067830.056
heart field specificationGO:000312810.055
regulation of biosynthetic processGO:00098892500.055
heterocycle biosynthetic processGO:00181302150.055
positive regulation of nucleic acid templated transcriptionGO:1903508570.054
nucleocytoplasmic transportGO:000691340.053
protein complex subunit organizationGO:0071822460.053
morphogenesis of an epithelial sheetGO:0002011490.053
cytoskeleton organizationGO:0007010960.053
blood vessel developmentGO:00015682460.052
Mouse
cell part morphogenesisGO:00329902460.051
embryonic viscerocranium morphogenesisGO:0048703520.051
regulation of metabolic processGO:00192223590.051
regulation of multicellular organismal processGO:00512392770.050
heart processGO:0003015710.049
specification of axis polarityGO:006500140.049
regulation of stem cell proliferationGO:007209120.048
determination of dorsal ventral asymmetryGO:0048262340.048
symbiosis encompassing mutualism through parasitismGO:004440340.048
nitrogen compound metabolic processGO:00068073190.048
regulation of protein targetingGO:190353320.047
transcription from rna polymerase ii promoterGO:0006366800.047
regulation of cell adhesionGO:0030155150.047
sensory organ morphogenesisGO:00905962000.047
negative regulation of signalingGO:0023057960.047
regulation of signal transductionGO:00099662250.047
protein localization to nucleusGO:003450430.047
negative regulation of cell communicationGO:0010648960.047
odontogenesis of dentin containing toothGO:004247510.046
protein import into nucleusGO:000660630.045
regulation of response to stimulusGO:00485832690.045
posterior lateral line developmentGO:0048916380.045
stem cell differentiationGO:00488631170.045
epiboly involved in gastrulation with mouth forming secondGO:0055113350.044
stem cell developmentGO:0048864820.044
positive regulation of macromolecule metabolic processGO:0010604930.044
muscle cell differentiationGO:00426921390.043
dorsal ventral pattern formationGO:00099531250.042
hepaticobiliary system developmentGO:0061008980.042
cell projection organizationGO:00300302840.042
cell substrate adhesionGO:003158940.042
microtubule based processGO:0007017600.041
pectoral fin developmentGO:0033339500.041
protein importGO:001703830.041
single organism nuclear importGO:190259330.041
cellular response to external stimulusGO:007149620.040
regulation of multicellular organismal developmentGO:20000262230.040
signal transductionGO:00071654550.039
positive regulation of dna templated transcription elongationGO:003278610.039
apoptotic processGO:00069151160.038
morphogenesis of a branching epitheliumGO:0061138160.038
Mouse
synaptic growth at neuromuscular junctionGO:005112420.038
regulation of protein localization to nucleusGO:190018020.038
agingGO:000756820.037
response to stressGO:00069502630.037
regulation of signalingGO:00230512350.037
specification of organ identityGO:001009220.036
positive regulation of cellular metabolic processGO:0031325940.036
negative regulation of cell developmentGO:0010721260.036
embryonic pectoral fin morphogenesisGO:0035118240.035
negative regulation of stem cell differentiationGO:200073720.035
cellular response to stressGO:0033554620.035
macromolecule biosynthetic processGO:00090592270.035
regulation of programmed cell deathGO:00430671010.035
dna templated transcription elongationGO:000635430.035
regionalizationGO:00030022740.035
muscle structure developmentGO:00610611960.035
system processGO:00030081850.035
protein targeting to nucleusGO:004474430.035
regulation of protein import into nucleusGO:004230620.034
cellular protein catabolic processGO:004425740.034
regulation of developmental processGO:00507932470.034
positive regulation of cellular biosynthetic processGO:0031328680.034
response to organic substanceGO:00100331530.033
nuclear importGO:005117030.032
camera type eye developmentGO:00430102220.032
regulation of nucleobase containing compound metabolic processGO:00192192500.032
cellular localizationGO:0051641970.032
positive regulation of nitrogen compound metabolic processGO:0051173690.032
cellular aromatic compound metabolic processGO:00067252950.032
endoderm developmentGO:0007492490.032
axonal defasciculationGO:000741420.031
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.030
multicellular organism reproductionGO:0032504350.030
cellular amino acid metabolic processGO:000652070.030
regulation of cell differentiationGO:00455951420.030
multicellular organism growthGO:003526440.030
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.030
immune system processGO:00023762410.029
protein localization to membraneGO:007265790.029
cellular process involved in reproduction in multicellular organismGO:0022412280.029
multi organism cellular processGO:004476420.029
negative regulation of multicellular organismal processGO:0051241690.029
cell morphogenesisGO:00009022890.028
cellular biosynthetic processGO:00442492860.028
central nervous system developmentGO:00074173870.028
positive regulation of nucleobase containing compound metabolic processGO:0045935690.027
striated muscle tissue developmentGO:00147061100.027
protein complex assemblyGO:0006461300.027
epidermis morphogenesisGO:004873040.027
chordate embryonic developmentGO:00430092710.027
Mouse
neuron projection developmentGO:00311751800.027
response to chemicalGO:00422213200.026
cellular response to nutrient levelsGO:003166920.026
actin cytoskeleton organizationGO:0030036630.026
somatic stem cell maintenanceGO:003501910.026
regulation of anatomical structure morphogenesisGO:00226031300.025
establishment of epithelial cell polarityGO:009016220.025
regulation of notch signaling pathwayGO:0008593160.025
embryo development ending in birth or egg hatchingGO:00097922710.025
Mouse
response to radiationGO:0009314510.024
methylationGO:0032259220.024
tube morphogenesisGO:00352393490.024
desmosome organizationGO:000293430.024
transcription elongation from rna polymerase ii promoterGO:000636830.024
transportGO:00068102200.024
regulation of neurogenesisGO:0050767870.024
intracellular signal transductionGO:0035556850.024
regulation of establishment of protein localizationGO:007020140.023
positive regulation of metabolic processGO:00098931080.023
cellular respirationGO:004533330.023
protein polymerizationGO:005125840.023
programmed cell deathGO:00125011190.023
meiotic chromosome segregationGO:004513230.023
heart contractionGO:0060047710.023
positive regulation of cell adhesionGO:004578510.023
cell cycle processGO:0022402530.022
regulation of system processGO:0044057400.022
neutrophil migrationGO:1990266100.022
positive regulation of transportGO:005105020.022
insulin like growth factor receptor signaling pathwayGO:004800940.022
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.022
negative regulation of immune responseGO:005077720.022
regulation of transcription from rna polymerase ii promoterGO:00063571140.022
regulation of cell deathGO:00109411030.021
epidermis developmentGO:0008544480.021
cellular response to extracellular stimulusGO:003166820.021
protein localizationGO:0008104400.021
microtubule organizing center organizationGO:003102310.021
larval developmentGO:000216420.021
mesenchymal cell differentiationGO:0048762870.021
regulation of cell communicationGO:00106462320.021
renal tubule morphogenesisGO:006133310.020
wound healingGO:0042060900.020
neuron developmentGO:00486662620.020
detection of stimulusGO:0051606290.020
cardiac conductionGO:006133730.020
positive regulation of cellular processGO:00485222010.020
negative regulation of cell migrationGO:0030336170.020
cellular response to starvationGO:000926710.020
dorsal fin developmentGO:003333710.020
tissue regenerationGO:0042246740.020
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.020
circulatory system processGO:0003013870.019
striated muscle cell differentiationGO:00511461290.019
regulation of dna templated transcription elongationGO:003278430.019
heart morphogenesisGO:00030071560.019
morphogenesis of follicular epitheliumGO:001633310.019
protein modification processGO:00362111000.019
single organism membrane fusionGO:004480120.019
myofibril assemblyGO:0030239480.019
liver developmentGO:0001889960.019
retina development in camera type eyeGO:00600411460.019
developmental maturationGO:0021700340.019
positive regulation of cell communicationGO:0010647560.019
embryonic appendage morphogenesisGO:0035113300.019
neuroblast fate commitmentGO:001401710.019
negative regulation of apoptotic processGO:0043066550.019
regulation of sodium ion transportGO:000202820.019
organonitrogen compound metabolic processGO:1901564740.019
cellular component disassemblyGO:002241110.018
oxoacid metabolic processGO:0043436310.018
positive regulation of gene expressionGO:0010628710.018
post anal tail morphogenesisGO:0036342190.018
axon developmentGO:00615641660.018
positive regulation of cellular component biogenesisGO:004408930.018
positive regulation of macromolecule biosynthetic processGO:0010557590.018
oogenesisGO:0048477140.018
cell agingGO:000756920.018
positive regulation of rna biosynthetic processGO:1902680570.018
regulation of cell cell adhesionGO:0022407130.018
regulation of cellular component sizeGO:0032535300.018
carbohydrate derivative metabolic processGO:1901135610.017
protein complex disassemblyGO:004324110.017
germ cell developmentGO:0007281220.017
regulation of intracellular protein transportGO:003315730.017
regulation of innate immune responseGO:0045088110.017
zymogen activationGO:003163830.016
connective tissue developmentGO:0061448990.016
negative regulation of cell differentiationGO:0045596460.016
multicellular organismal signalingGO:0035637220.016
macromolecule modificationGO:00434121110.016
regulation of proteolysisGO:0030162240.016
neuroblast proliferationGO:000740520.016
epidermal cell differentiationGO:0009913360.016
cellular response to chemical stimulusGO:00708871570.016
actin filament based movementGO:003004810.016
single organism reproductive processGO:0044702400.016
Mouse
inner ear receptor cell developmentGO:0060119200.016
positive regulation of gliogenesisGO:001401520.016
apical junction assemblyGO:004329710.015
cell cycleGO:0007049930.015
regulation of cell morphogenesisGO:0022604420.015
action potentialGO:0001508190.015
epithelial tube morphogenesisGO:00605621480.015
cellular carbohydrate metabolic processGO:004426240.015
regulation of vasculature developmentGO:1901342330.015
developmental growthGO:00485891660.015
morphogenesis of a branching structureGO:0001763210.015
Mouse
regulation of blood circulationGO:1903522320.015
sexual reproductionGO:0019953360.015
negative regulation of cytokine productionGO:000181810.015
endothelial cell differentiationGO:0045446200.015
calcium independent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633810.015
regulation of multicellular organism growthGO:004001440.015
cellular response to organic substanceGO:00713101050.015
mechanoreceptor differentiationGO:0042490370.015
actin polymerization or depolymerizationGO:000815420.015
axis elongationGO:0003401310.015
embryonic pattern specificationGO:0009880440.015
phenol containing compound biosynthetic processGO:004618940.015
cellular component assemblyGO:00226071700.015
negative regulation of macromolecule biosynthetic processGO:0010558480.015
s adenosylmethionine metabolic processGO:004650010.015
regulation of cellular protein catabolic processGO:190336210.015
epithelial cell morphogenesisGO:000338220.015
small molecule metabolic processGO:0044281770.014
phosphate containing compound metabolic processGO:00067961080.014
endodermal cell fate determinationGO:000749320.014
regulation of cytoplasmic transportGO:190364940.014
regulation of protein complex disassemblyGO:004324410.014
regulation of localizationGO:00328791040.014
cellular response to oxygen levelsGO:007145310.014
endothelium developmentGO:0003158250.014
proteasomal protein catabolic processGO:001049820.014
single fertilizationGO:000733830.014
regulation of epidermis developmentGO:004568220.014
regulation of cell activationGO:005086510.014
hair cell differentiationGO:0035315320.014
membrane organizationGO:0061024210.014
developmental programmed cell deathGO:001062340.014
regulation of membrane potentialGO:0042391230.014
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.013
cell junction assemblyGO:003432970.013
regulation of cytokine productionGO:000181730.013
regenerationGO:0031099910.013
defense response to other organismGO:0098542330.013
deathGO:00162651210.013
positive regulation of biosynthetic processGO:0009891680.013
cell deathGO:00082191210.013
regulation of cellular ketone metabolic processGO:001056570.013
wnt signaling pathwayGO:0016055800.013
cellular protein modification processGO:00064641000.013
meiosis iGO:000712710.013
caudal fin morphogenesisGO:003514370.013
meiotic cell cycle processGO:190304630.013
caudal fin developmentGO:003333690.013
homeostatic processGO:00425921420.012
tissue migrationGO:0090130370.012
establishment of localizationGO:00512342440.012
carboxylic acid metabolic processGO:0019752220.012
negative regulation of programmed cell deathGO:0043069580.012
cellular response to xenobiotic stimulusGO:0071466350.012
intramembranous ossificationGO:000195730.012
lymphocyte proliferationGO:004665110.012
regulation of protein transportGO:005122330.012
adult behaviorGO:003053420.012
cellular macromolecule localizationGO:0070727210.012
proteolysisGO:0006508380.012
regulation of water loss via skinGO:003356110.012
nephron tubule morphogenesisGO:007207810.012
renal system vasculature morphogenesisGO:006143810.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
regulation of heart contractionGO:0008016320.012
carbohydrate biosynthetic processGO:001605110.012
skeletal system morphogenesisGO:00487051020.012
cellular response to growth factor stimulusGO:0071363390.012
branching morphogenesis of an epithelial tubeGO:0048754150.012
myeloid leukocyte migrationGO:0097529120.012
establishment of epithelial cell apical basal polarityGO:004519820.012
regulation of molecular functionGO:0065009700.011
cognitionGO:005089010.011
mesenchyme developmentGO:00604851270.011
regulation of cell proliferationGO:0042127370.011
regulation of metal ion transportGO:001095940.011
pigment cell developmentGO:007028530.011
detection of abiotic stimulusGO:0009582240.011
cell substrate junction assemblyGO:000704420.011
melanin biosynthetic processGO:004243810.011
canonical wnt signaling pathwayGO:0060070480.011
developmental growth involved in morphogenesisGO:0060560860.011
cell divisionGO:0051301200.011
organic acid metabolic processGO:0006082310.011
neural crest cell differentiationGO:0014033720.011
muscle system processGO:0003012200.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
signal transduction by p53 class mediatorGO:0072331130.011
secondary metabolic processGO:001974830.011
asymmetric protein localizationGO:000810560.011
pectoral fin morphogenesisGO:0035138290.011
mononuclear cell proliferationGO:003294310.011
actin filament based processGO:0030029640.011
blood circulationGO:0008015870.011
negative regulation of cellular metabolic processGO:0031324770.011
multi organism processGO:00517041340.011
single organism cellular localizationGO:1902580460.011
cytokinesisGO:000091030.011
axon ensheathmentGO:0008366180.011
regulation of cell migrationGO:0030334400.011
axonogenesisGO:00074091520.010
negative regulation of developmental processGO:0051093650.010
negative regulation of signal transduction in absence of ligandGO:190109910.010
axis specificationGO:0009798430.010
regulation of cellular component organizationGO:0051128860.010
peptidyl serine modificationGO:001820920.010
regulation of carbohydrate metabolic processGO:000610940.010
cellular component maintenanceGO:004395430.010
cartilage developmentGO:0051216960.010
regulation of cellular protein metabolic processGO:0032268520.010
sensory perceptionGO:0007600390.010
negative regulation of neural precursor cell proliferationGO:200017810.010
pigmentationGO:0043473850.010
cellular protein complex assemblyGO:0043623190.010

spint1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.060
myopathyDOID:42300.026
heart diseaseDOID:11400.026
cardiomyopathyDOID:005070000.026
musculoskeletal system diseaseDOID:1700.026
muscle tissue diseaseDOID:6600.026
muscular diseaseDOID:008000000.026
cardiovascular system diseaseDOID:128700.026
disease of cellular proliferationDOID:1456600.024
disease of metabolismDOID:001466700.024
cancerDOID:16200.019
organ system cancerDOID:005068600.019
acquired metabolic diseaseDOID:006015800.019
thoracic cancerDOID:509300.015
breast cancerDOID:161200.015
reproductive organ cancerDOID:19300.011
amyloidosisDOID:912000.010