Danio rerio

19 known processes

sppl3

signal peptide peptidase 3

(Aliases: zgc:114093,wu:fb94d08,fb94d08)

sppl3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to external stimulusGO:00096052640.054
larval developmentGO:000216420.047
morphogenesis of an epitheliumGO:00020093330.043
regulation of protein transportGO:005122330.038
cell morphogenesis involved in differentiationGO:00009041950.038
positive regulation of transportGO:005105020.037
meiotic nuclear divisionGO:000712640.036
mitochondrion organizationGO:000700540.035
cognitionGO:005089010.035
synaptic growth at neuromuscular junctionGO:005112420.035
cell morphogenesisGO:00009022890.034
positive regulation of cytoskeleton organizationGO:005149530.034
cellular response to external stimulusGO:007149620.034
proteolysis involved in cellular protein catabolic processGO:005160330.033
lateral inhibitionGO:004633110.033
positive regulation of cellular component biogenesisGO:004408930.032
inositol lipid mediated signalingGO:004801720.031
regulation of synapse organizationGO:005080730.031
single fertilizationGO:000733830.031
regulation of reproductive processGO:200024140.031
convergent extension involved in gastrulationGO:0060027710.029
establishment of protein localization to organelleGO:007259440.029
regulation of nucleic acid templated transcriptionGO:19035062130.028
regulation of signalingGO:00230512350.028
regulation of synaptic growth at neuromuscular junctionGO:000858210.028
modification dependent protein catabolic processGO:001994130.027
exocytosisGO:000688710.027
regulation of multicellular organismal processGO:00512392770.027
protein secretionGO:000930610.027
phagocytosisGO:000690930.027
regulation of protein complex assemblyGO:004325430.027
regulation of synapse assemblyGO:005196330.027
cellular component movementGO:00069283350.027
convergent extensionGO:00600261180.026
regulation of establishment of protein localizationGO:007020140.026
tube morphogenesisGO:00352393490.026
agingGO:000756820.026
neurotransmitter transportGO:000683620.025
cell surface receptor signaling pathwayGO:00071663250.025
signal transductionGO:00071654550.025
protein localization to nucleusGO:003450430.025
regulation of cell activationGO:005086510.024
modification dependent macromolecule catabolic processGO:004363230.024
digestive tract morphogenesisGO:00485462310.024
rna metabolic processGO:00160702190.024
nucleocytoplasmic transportGO:000691340.024
amine metabolic processGO:000930820.024
positive regulation of cellular catabolic processGO:003133130.024
fertilizationGO:000956630.024
organelle organizationGO:00069962270.023
regulation of nucleobase containing compound metabolic processGO:00192192500.023
regulation of cellular amine metabolic processGO:003323800.023
regulation of nitrogen compound metabolic processGO:00511712510.023
synaptic vesicle transportGO:004848910.023
nuclear importGO:005117030.023
regulation of cytokine productionGO:000181730.023
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.023
actin polymerization or depolymerizationGO:000815420.023
positive regulation of gtpase activityGO:004354710.023
regulation of metabolic processGO:00192223590.022
digestive tract developmentGO:00485652650.022
negative regulation of secretionGO:005104820.022
negative regulation of biological processGO:00485193040.022
cell projection morphogenesisGO:00488582440.022
regulation of cytoplasmic transportGO:190364940.022
meiotic cell cycle processGO:190304630.022
regulation of nucleotide catabolic processGO:003081120.022
positive regulation of catabolic processGO:000989640.022
single organism organelle organizationGO:19025891990.022
cell part morphogenesisGO:00329902460.022
positive regulation of cytosolic calcium ion concentrationGO:000720440.021
cellular component morphogenesisGO:00329893360.021
regulation of gtp catabolic processGO:003312420.021
positive regulation of immune effector processGO:000269930.021
positive regulation of cytokine productionGO:000181920.021
nuclear transportGO:005116940.021
positive regulation of cell cycleGO:004578730.021
hemopoiesisGO:00300971830.021
single organism nuclear importGO:190259330.021
protein complex disassemblyGO:004324110.021
specification of symmetryGO:00097992040.021
gastrulationGO:00073692080.021
proteasomal protein catabolic processGO:001049820.021
cellular amine metabolic processGO:004410620.021
protein metabolic processGO:00195381830.021
Fly
cellular macromolecule metabolic processGO:00442603910.020
Fly
maintenance of locationGO:005123540.020
cellular response to nutrient levelsGO:003166920.020
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.020
positive regulation of secretionGO:005104710.020
regulation of stem cell differentiationGO:200073640.020
phosphatidylinositol mediated signalingGO:004801520.020
positive regulation of cell activationGO:005086710.020
negative regulation of kinase activityGO:003367340.020
regulation of cellular amino acid metabolic processGO:000652100.020
symbiosis encompassing mutualism through parasitismGO:004440340.020
positive regulation of cellular processGO:00485222010.020
regulation of mrna processingGO:005068430.020
protein importGO:001703830.019
ubiquitin dependent protein catabolic processGO:000651130.019
transcription dna templatedGO:00063511810.019
cellular ketone metabolic processGO:0042180110.019
protein import into nucleusGO:000660630.019
system processGO:00030081850.019
regulation of cellular ketone metabolic processGO:001056570.019
positive regulation of purine nucleotide catabolic processGO:003312310.019
chordate embryonic developmentGO:00430092710.019
gene expressionGO:00104672520.019
Fly
response to chemicalGO:00422213200.019
digestive system developmentGO:00551232890.019
small molecule catabolic processGO:004428230.019
guanosine containing compound metabolic processGO:190106840.019
cell motilityGO:00488702440.019
adult behaviorGO:003053420.019
gtp metabolic processGO:004603940.018
cellular component disassemblyGO:002241110.018
regulation of purine nucleotide catabolic processGO:003312120.018
guanosine containing compound catabolic processGO:190106920.018
positive regulation of gtp catabolic processGO:003312610.018
positive regulation of secretion by cellGO:190353210.018
negative regulation of protein phosphorylationGO:000193340.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
macromolecule modificationGO:00434121110.018
regulation of nucleoside metabolic processGO:000911820.018
positive regulation of small gtpase mediated signal transductionGO:005105710.018
regulation of gene expressionGO:00104682650.018
nucleobase containing compound metabolic processGO:00061392740.018
phosphatidylinositol 3 kinase signalingGO:001406520.018
rna modificationGO:000945120.017
gtp catabolic processGO:000618420.017
heterocycle biosynthetic processGO:00181302150.017
synaptic vesicle localizationGO:009747910.017
positive regulation of nucleoside metabolic processGO:004597910.017
production of molecular mediator of immune responseGO:000244020.017
regulation of macromolecule metabolic processGO:00602553170.017
organic cyclic compound metabolic processGO:19013603010.017
blood vessel developmentGO:00015682460.017
primary neural tube formationGO:001402010.017
regulation of primary metabolic processGO:00800903110.017
establishment of localizationGO:00512342440.017
cell migrationGO:00164772370.017
locomotionGO:00400113130.017
nucleic acid metabolic processGO:00903042440.017
regulation of nucleocytoplasmic transportGO:004682220.017
cell projection organizationGO:00300302840.017
organic acid catabolic processGO:001605430.017
hematopoietic or lymphoid organ developmentGO:00485341910.017
nitrogen compound metabolic processGO:00068073190.016
Fly
chemosensory behaviorGO:000763510.016
macromolecule biosynthetic processGO:00090592270.016
nucleic acid templated transcriptionGO:00976591810.016
regulation of response to biotic stimulusGO:000283120.016
sequestering of metal ionGO:005123830.016
small gtpase mediated signal transductionGO:000726480.016
single organism localizationGO:19025782250.016
regulation of developmental processGO:00507932470.016
axonogenesisGO:00074091520.016
protein acylationGO:004354330.016
multicellular organism growthGO:003526440.016
cellular response to starvationGO:000926710.016
immune system developmentGO:00025201910.016
ras protein signal transductionGO:000726570.016
internal peptidyl lysine acetylationGO:001839320.016
cellular protein catabolic processGO:004425740.016
regulation of synaptic plasticityGO:004816710.016
regulation of cell shapeGO:000836010.016
peptidyl threonine phosphorylationGO:001810710.015
protein targeting to nucleusGO:004474430.015
cytosolic calcium ion transportGO:006040130.015
neuron projection morphogenesisGO:00488121610.015
embryo development ending in birth or egg hatchingGO:00097922710.015
stem cell maintenanceGO:001982740.015
erk1 and erk2 cascadeGO:007037140.015
biosynthetic processGO:00090582940.015
negative regulation of stem cell differentiationGO:200073720.015
negative regulation of catabolic processGO:000989530.015
determination of bilateral symmetryGO:00098552040.015
regulation of cell projection assemblyGO:006049140.015
macromolecular complex disassemblyGO:003298410.015
organic cyclic compound biosynthetic processGO:19013622230.015
cellular protein metabolic processGO:00442671290.015
Fly
enzyme linked receptor protein signaling pathwayGO:00071671060.015
regulation of mrna splicing via spliceosomeGO:004802430.015
cellular macromolecule biosynthetic processGO:00346452240.015
regulation of inflammatory responseGO:005072720.015
immune system processGO:00023762410.015
protein acetylationGO:000647320.015
leukocyte mediated cytotoxicityGO:000190910.015
peptidyl lysine acetylationGO:001839420.015
regulation of cellular metabolic processGO:00313233200.015
golgi vesicle transportGO:004819330.015
peptide transportGO:001583310.015
phagocytosis engulfmentGO:000691110.015
regulation of cell communicationGO:00106462320.015
regulation of macromolecule biosynthetic processGO:00105562250.015
positive regulation of cellular amine metabolic processGO:003324000.015
response to external biotic stimulusGO:0043207970.015
regulation of stem cell proliferationGO:007209120.015
regulation of rho protein signal transductionGO:003502320.015
cellular localizationGO:0051641970.015
cellular nitrogen compound metabolic processGO:00346412900.015
Fly
positive regulation of nitrogen compound metabolic processGO:0051173690.015
regulation of response to stimulusGO:00485832690.015
negative regulation of protein kinase activityGO:000646940.014
coagulationGO:0050817130.014
cellular component assemblyGO:00226071700.014
transcription from rna polymerase ii promoterGO:0006366800.014
negative regulation of cellular catabolic processGO:003133030.014
extrinsic apoptotic signaling pathwayGO:009719130.014
regulation of signal transductionGO:00099662250.014
interspecies interaction between organismsGO:004441940.014
carboxylic acid catabolic processGO:004639530.014
response to stressGO:00069502630.014
cellular response to extracellular stimulusGO:003166820.014
microtubule organizing center organizationGO:003102310.014
phosphorus metabolic processGO:00067931090.014
cellular component biogenesisGO:00440851780.014
regulation of protein ubiquitinationGO:003139630.014
establishment of synaptic vesicle localizationGO:009748010.014
response to other organismGO:0051707970.014
regulation of protein localization to nucleusGO:190018020.014
negative regulation of sequestering of calcium ionGO:005128340.014
g1 s transition of mitotic cell cycleGO:000008210.014
sensory organ developmentGO:00074233930.014
regulation of bindingGO:005109830.014
positive regulation of protein complex assemblyGO:003133420.014
heterocycle metabolic processGO:00464832900.014
organonitrogen compound metabolic processGO:1901564740.014
Fly
regulation of reactive oxygen species metabolic processGO:200037720.014
regulation of erk1 and erk2 cascadeGO:007037240.014
leukocyte proliferationGO:007066110.014
regulation of gtpase activityGO:004308720.014
internal protein amino acid acetylationGO:000647520.014
regulation of calcium ion transportGO:005192420.014
regulation of blood pressureGO:000821710.014
compound eye developmentGO:004874920.013
embryonic organ developmentGO:00485683810.013
rna biosynthetic processGO:00327741810.013
tube closureGO:006060610.013
regulation of multicellular organism growthGO:004001440.013
negative regulation of mapk cascadeGO:004340940.013
neuron differentiationGO:00301823530.013
mitochondrial transportGO:000683920.013
negative regulation of defense responseGO:003134820.013
axon developmentGO:00615641660.013
regulation of protein targetingGO:190353320.013
i kappab kinase nf kappab signalingGO:000724940.013
primitive hemopoiesisGO:0060215270.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
protein dephosphorylationGO:000647030.013
vasculature developmentGO:00019442780.013
cellular amino acid metabolic processGO:000652070.013
cytoskeleton dependent cytokinesisGO:006164030.013
regulation of meiotic cell cycleGO:005144510.013
response to carbohydrateGO:000974330.013
spermatid developmentGO:000728620.013
single organism metabolic processGO:00447102170.013
multi organism processGO:00517041340.013
neurotransmitter secretionGO:000726920.013
mechanosensory behaviorGO:000763820.013
regulation of microtubule cytoskeleton organizationGO:007050730.013
cellular aromatic compound metabolic processGO:00067252950.013
oxoacid metabolic processGO:0043436310.013
phosphate containing compound metabolic processGO:00067961080.013
regulation of protein complex disassemblyGO:004324410.013
growthGO:00400071740.013
peptidyl threonine modificationGO:001821010.013
regulation of intracellular protein transportGO:003315730.012
establishment of endothelial barrierGO:006102830.012
neuron neuron synaptic transmissionGO:000727010.012
regulation of leukocyte mediated cytotoxicityGO:000191010.012
heart developmentGO:00075073130.012
regulation of protein polymerizationGO:003227120.012
germ line stem cell maintenanceGO:003071820.012
centrosome organizationGO:005129710.012
carboxylic acid metabolic processGO:0019752220.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
somatic stem cell maintenanceGO:003501910.012
regulation of multicellular organismal developmentGO:20000262230.012
regulation of dna replicationGO:000627530.012
meiosis iGO:000712710.012
regulation of dendrite developmentGO:005077330.012
positive regulation of stress activated mapk cascadeGO:003287430.012
cellular biosynthetic processGO:00442492860.012
regionalizationGO:00030022740.012
neuroblast proliferationGO:000740520.012
membrane invaginationGO:001032410.012
female sex differentiationGO:004666040.012
cell cycle g1 s phase transitionGO:004484310.012
regulation of exocytosisGO:001715710.012
establishment of localization in cellGO:0051649770.012
stem cell differentiationGO:00488631170.012
spindle assemblyGO:005122520.012
regulation of tube sizeGO:003515020.012
centrosome duplicationGO:005129810.012
cytokinesisGO:000091030.012
regulation of alternative mrna splicing via spliceosomeGO:000038110.012
regulation of rna metabolic processGO:00512522240.012
adherens junction organizationGO:003433240.012
ribonucleoside monophosphate catabolic processGO:000915840.012
toll like receptor signaling pathwayGO:000222440.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
negative regulation of cellular processGO:00485232830.012
organic acid metabolic processGO:0006082310.012
regulation of blood coagulationGO:003019310.011
sensory perception of painGO:001923310.011
post golgi vesicle mediated transportGO:000689210.011
developmental growthGO:00485891660.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
response to monosaccharideGO:003428430.011
response to biotic stimulusGO:0009607970.011
establishment of protein localization to plasma membraneGO:009000210.011
fibroblast growth factor receptor signaling pathwayGO:0008543220.011
generation of neuronsGO:00486993850.011
regulation of biosynthetic processGO:00098892500.011
negative regulation of cytokine productionGO:000181810.011
stem cell proliferationGO:007208940.011
rna localizationGO:000640340.011
regulation of neural precursor cell proliferationGO:200017730.011
regulation of epithelial cell proliferationGO:005067830.011
antimicrobial humoral responseGO:001973020.011
divalent inorganic cation homeostasisGO:0072507220.011
cell killingGO:000190620.011
regulation of protein depolymerizationGO:190187910.011
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.011
protein localization to plasma membraneGO:007265910.011
calcium ion dependent exocytosisGO:001715610.011
nuclear migrationGO:000709730.011
localization of cellGO:00516742440.011
cellular response to radiationGO:007147840.011
cellular response to oxygen levelsGO:007145310.011
cellular response to decreased oxygen levelsGO:003629410.011
retina development in camera type eyeGO:00600411460.011
positive regulation of ras protein signal transductionGO:004657910.011
purine nucleoside monophosphate catabolic processGO:000912840.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
cellular response to biotic stimulusGO:007121630.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
neuron projection developmentGO:00311751800.011
negative regulation of map kinase activityGO:004340720.011
regulation of leukocyte mediated immunityGO:000270310.011
nucleoside monophosphate catabolic processGO:000912540.011
nucleobase containing compound biosynthetic processGO:00346542050.011
meiotic chromosome segregationGO:004513230.011
protein polymerizationGO:005125840.011
positive regulation of stem cell proliferationGO:200064810.011
cellular response to hypoxiaGO:007145610.011
transportGO:00068102200.011
mesenchyme developmentGO:00604851270.011
developmental growth involved in morphogenesisGO:0060560860.011
taxisGO:00423301090.011
eye developmentGO:00016542770.011
regulation of ras gtpase activityGO:003231820.011
regulation of wound healingGO:006104120.010
regulation of metal ion transportGO:001095940.010
positive regulation of ras gtpase activityGO:003232010.010
response to drugGO:004249330.010
positive regulation of erk1 and erk2 cascadeGO:007037420.010
negative regulation of multi organism processGO:004390130.010
protein polyubiquitinationGO:000020940.010
regulation of cellular response to growth factor stimulusGO:0090287350.010
regulation of rna biosynthetic processGO:20011412130.010
protein modification processGO:00362111000.010
angiogenesisGO:00015251580.010
negative regulation of tor signalingGO:003200720.010
purine ribonucleoside monophosphate catabolic processGO:000916940.010
cellular protein modification processGO:00064641000.010
cellular nitrogen compound biosynthetic processGO:00442712180.010
regulation of protein catabolic processGO:004217610.010
b cell activationGO:004211320.010
regulation of jak stat cascadeGO:004642530.010
regulation of cell differentiationGO:00455951420.010
regulation of production of molecular mediator of immune responseGO:000270010.010
regulation of i kappab kinase nf kappab signalingGO:004312240.010
regulation of autophagyGO:001050630.010
positive regulation of dna metabolic processGO:005105410.010
tissue remodelingGO:004877140.010
cytoskeleton organizationGO:0007010960.010
release of sequestered calcium ion into cytosolGO:005120930.010
regulation of filopodium assemblyGO:005148920.010
response to woundingGO:00096111160.010
positive regulation of nucleotide catabolic processGO:003081310.010

sppl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.029
nervous system diseaseDOID:86300.019
disease of metabolismDOID:001466700.014
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.010